Shibata Mikihiro 柴田幹大

Researcher Number	80631027
Other IDs	https://orcid.org/0000-0001-5041-3979
Affiliation (Current)	2024: 金沢大学, ナノ生命科学研究所, 教授
Affiliation (based on the past Project Information) *help	2020 – 2024: 金沢大学, ナノ生命科学研究所, 教授 2018 – 2019: 金沢大学, ナノ生命科学研究所, 准教授 2016 – 2017: 金沢大学, 新学術創成研究機構, 准教授
Review Section/Research Field	Principal Investigator Biological Sciences / Basic Section 28040:Nanobioscience-related / Medium-sized Section 43:Biology at molecular to cellular levels, and related fields / Medium-sized Section 28:Nano/micro science and related fields / Biophysics Except Principal Investigator Structural biochemistry
Keywords	Principal Investigator バイオイメージング / 一分子計測・操作 / １分子計測・操作 / １分子イメージング・ナノ計測 / 1分子イメージング・ナノ計測 / 原子間力顕微鏡 / タンパク質 / 超分子複合体 / クロマチン動態 / タンパク質・酵素化学 … More / ゲノム工学 / 天然変性タンパク質 / ヌクレオソーム / 脳機能 / 記憶・学習 / 画像解析 / ナノバイオ / 走査プローブ顕微鏡 / 生物物理 / ナノサイエンス / 神経科学 / 高速原子間力顕微鏡 / 走査型プローブ顕微鏡 / プロテインキナーゼ / 記憶 … More Except Principal Investigator CRISPR-Cas9 / Ribonuclease / Crystal structure / Maelstrom / 結晶構造 / RNA / ゲノム編集 / piRNA / Argonaute / Cas9 / CRISPR / 非コードRNA Less

Real-space and real-time visualization of histone tails by single-molecule imagingPrincipal Investigator
- Principal Investigator
  
  柴田幹大
- Project Period (FY)
  2024 – 2025
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Review Section
  
  Medium-sized Section 43:Biology at molecular to cellular levels, and related fields
- Research Institution
  Kanazawa University
Real-time and real-space imaging of chromatin remodelingPrincipal Investigator
- Principal Investigator
  
  柴田幹大
- Project Period (FY)
  2021 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Review Section
  
  Biological Sciences
- Research Institution
  Kanazawa University
Investigation of molecular insight into genome editing tools by single-molecule imagingPrincipal Investigator
- Principal Investigator
  
  柴田幹大
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 28040:Nanobioscience-related
- Research Institution
  Kanazawa University
Challenge to elucidate the molecular mechanism of memory by single molecule imagingPrincipal Investigator
- Principal Investigator
  
  Shibata Mikihiro
- Project Period (FY)
  2020 – 2021
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Review Section
  
  Medium-sized Section 28:Nano/micro science and related fields
- Research Institution
  Kanazawa University
Real-time and real-space imaging of chromatin dynamicsPrincipal Investigator
- Principal Investigator
  
  柴田幹大
- Project Period (FY)
  2019 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Review Section
  
  Biological Sciences
- Research Institution
  Kanazawa University
Challenge to near atomic resolution AFM image by fusion of high-speed AFM and advanced image analysisPrincipal Investigator
- Principal Investigator
  
  Mikihiro Shibata
- Project Period (FY)
  2018 – 2019
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Review Section
  
  Medium-sized Section 43:Biology at molecular to cellular levels, and related fields
- Research Institution
  Kanazawa University
Comprehensive studies of working mechanism of Cas proteins using HS-AFMPrincipal Investigator
- Principal Investigator
  
  Shibata Mikihiro
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 28040:Nanobioscience-related
- Research Institution
  Kanazawa University
HS-AFM studies of molecular mechanisms of learning and memory in CaMKII oligomerPrincipal Investigator
- Principal Investigator
  
  Shibata Mikihiro
- Project Period (FY)
  2016 – 2017
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Biophysics
- Research Institution
  Kanazawa University
Elucidation of molecular mechanisms of RNA silencing
- Principal Investigator
  
  Nishimasu Hiroshi
- Project Period (FY)
  2014 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Structural biochemistry
- Research Institution
  The University of Tokyo

All 2023 2022 2021 2020 2019 2018 2017 2016

All Journal Article Presentation Patent

[Journal Article] High-Speed Atomic Force Microscopy Reveals Spontaneous Nucleosome Sliding of H2A.Z at the Subsecond Time Scale2023
- Author(s)
  Morioka Shin、Sato Shoko、Horikoshi Naoki、Kujirai Tomoya、Tomita Takuya、Baba Yudai、Kakuta Takahiro、Ogoshi Tomoki、Puppulin Leonardo、Sumino Ayumi、Umeda Kenichi、Kodera Noriyuki、Kurumizaka Hitoshi、Shibata Mikihiro
- Journal Title
  
  Nano Letters
  
  Volume: 23 Issue: 5 Pages: 1696-1704
- DOI
  10.1021/acs.nanolett.2c04346
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K04849, KAKENHI-PROJECT-22K19290, KAKENHI-PROJECT-20H00327, KAKENHI-PROJECT-21H01771, KAKENHI-PLANNED-18H05534, KAKENHI-PUBLICLY-21H00247, KAKENHI-PROJECT-23K23187
[Journal Article] Dynamics of Target DNA Binding and Cleavage by Staphylococcus aureus Cas9 as Revealed by High-Speed Atomic Force Microscopy2023
- Author(s)
  Puppulin Leonardo、Ishikawa Junichiro、Sumino Ayumi、Marchesi Arin、Flechsig Holger、Umeda Kenichi、Kodera Noriyuki、Nishimasu Hiroshi、Shibata Mikihiro
- Journal Title
  
  ACS Nano
  
  Volume: 17 Issue: 5 Pages: 4629-4641
- DOI
  10.1021/acsnano.2c10709
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K04849, KAKENHI-PROJECT-22K19290, KAKENHI-PROJECT-20H00327, KAKENHI-PROJECT-21H01771, KAKENHI-PUBLICLY-21H00247, KAKENHI-PROJECT-23K23187
[Journal Article] Designing receptor agonists with enhanced pharmacokinetics by grafting macrocyclic peptides into fragment crystallizable regions2022
- Author(s)
  Sakai Katsuya、Sugano-Nakamura Nozomi、Mihara Emiko、Rojas-Chaverra Nichole Marcela、Watanabe Sayako、Sato Hiroki、Imamura Ryu、Voon Dominic Chih-Cheng、Sakai Itsuki、Yamasaki Chihiro、Tateno Chise、Shibata Mikihiro、Suga Hiroaki、Takagi Junichi、Matsumoto Kunio
- Journal Title
  
  Nature Biomedical Engineering
  
  Volume: 7 Issue: 2 Pages: 164-176
- DOI
  10.1038/s41551-022-00955-6
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K18250, KAKENHI-PROJECT-21K15482, KAKENHI-PROJECT-20H05618, KAKENHI-PROJECT-20H00455, KAKENHI-PROJECT-21H01771, KAKENHI-PROJECT-20K06553, KAKENHI-PUBLICLY-21H00247
[Journal Article] Histone variant H2A.B-H2B dimers are spontaneously exchanged with canonical H2A-H2B in the nucleosome2021
- Author(s)
  Rina Hirano, Yasuhiro Arimura, Tomoya Kujirai, Mikihiro Shibata, Aya Okuda, Ken Morishima, Rintaro Inoue, Masaaki Sugiyama, Hitoshi Kurumizaka
- Journal Title
  
  Communications Biology
  
  Volume: 4 Issue: 1 Pages: 1-11
- DOI
  10.1038/s42003-021-01707-z
- NAID
  120006960298
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K21122, KAKENHI-PLANNED-18H05534, KAKENHI-PUBLICLY-19H05257, KAKENHI-PROJECT-18H05229, KAKENHI-PROJECT-20H00449, KAKENHI-PROJECT-18H01836, KAKENHI-PROJECT-21K15051
[Journal Article] Macrocyclic Peptide-Conjugated Tip for Fast and Selective Molecular Recognition Imaging by High-Speed Atomic Force Microscopy2021
- Author(s)
  L. Pupplin, D. Kanayama, N. Terasaka, K. Sakai, N. Kodera, K. Umeda, A. Sumino, M. Arin, W. Wei, H. Tanaka, T. Fukuma, H. Suga, K. Matsumoto, M. Shibata
- Journal Title
  
  ACS Applied Materials & Interfaces
  
  Volume: 13(46) Issue: 46 Pages: 54817-54829
- DOI
  10.1021/acsami.1c17708
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K19422, KAKENHI-PROJECT-20K21122, KAKENHI-PUBLICLY-21H00247, KAKENHI-PLANNED-21H05251, KAKENHI-PROJECT-20H00327, KAKENHI-PROJECT-19H03499, KAKENHI-PROJECT-21H01771, KAKENHI-PROJECT-17H05058, KAKENHI-PROJECT-20K06553, KAKENHI-PROJECT-21K04849, KAKENHI-PROJECT-21K18250, KAKENHI-PROJECT-21H04127
[Journal Article] Applicability of Styrene-Maleic Acid Copolymer for Two Microbial Rhodopsins, RxR and HsSRI.2020
- Author(s)
  Tetsuya Ueta, Keiichi Kojima, Tomoya Hino, Mikihiro Shibata, Shingo Nagano, Yuki Sudo*
- Journal Title
  
  Biophysical journal
  
  Volume: 119 Issue: 9 Pages: 1760-1770
- DOI
  10.1016/j.bpj.2020.09.026
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20K21122, KAKENHI-PROJECT-20K21482, KAKENHI-PUBLICLY-19H04727, KAKENHI-PUBLICLY-19H05257, KAKENHI-PUBLICLY-19H05396, KAKENHI-PUBLICLY-20H05445, KAKENHI-PROJECT-18H01836, KAKENHI-PROJECT-18H02411, KAKENHI-PROJECT-18K06156, KAKENHI-PROJECT-19K16090
[Journal Article] Macrocyclic peptide-based inhibition and imaging of hepatocyte growth factor.2019
- Author(s)
  Katsuya Sakai, Toby Passioura, Hiroki Sato, Kenichiro Ito, Hiroki Furuhashi, Masataka Umitsu, Junichi Takagi, Yukinari Kato, Hidefumi Mukai, Shota Warashina, Maki Zouda, Yasuyoshi Watanabe, Seiji Yano, Mikihiro Shibata, Hiroaki Suga, and Kunio Matsumoto
- Journal Title
  
  Nat. Chem. Biol.
  
  Volume: 印刷中
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18H01836
[Journal Article] Crystal structure of heliorhodopsin2019
- Author(s)
  W. Shihoya, K. Inoue, M. Singh, M. Konno, S. Hososhima, K. Yamashita, K. Ikeda, A. Higuchi, T. Izume, Okazaki S, Hashimoto M, Mizutori R, Tomida S, Yamauchi Y, Abe-Yoshizumi R, K. Katayama, SP. Tsunoda, M. Shibata, Y. Furutani, A. Pushkarev, O. Béjà, T. Uchihashi, H. Kandori, O. Nureki
- Journal Title
  
  Nature
  
  Volume: 574 Issue: 7776 Pages: 132-136
- DOI
  10.1038/s41586-019-1604-6
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K06109, KAKENHI-PUBLICLY-18H04512, KAKENHI-PUBLICLY-19H04959, KAKENHI-PUBLICLY-19H05257, KAKENHI-PUBLICLY-19H05389, KAKENHI-PROJECT-18H03986, KAKENHI-PROJECT-17H03007, KAKENHI-PROJECT-18H01836, KAKENHI-PROJECT-18H01837, KAKENHI-PROJECT-17J30010, KAKENHI-PROJECT-19J22788, KAKENHI-PROJECT-17K19230, KAKENHI-PROJECT-18K19287, KAKENHI-PROJECT-16H06294
[Journal Article] Macrocyclic peptide-based inhibition and imaging of hepatocyte growth factor.2019
- Author(s)
  Sakai K, Passioura T, Sato H, Ito K, Furuhashi H, Umitsu M, Takagi J, Kato Y, Mukai H, Warashina S, Zouda M, Watanabe Y, Yano S, Shibata M, Suga H, Matsumoto K
- Journal Title
  
  Nature Chemical Biology
  
  Volume: 15 Issue: 6 Pages: 598-606
- DOI
  10.1038/s41589-019-0285-7
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K15306, KAKENHI-PUBLICLY-19H05257, KAKENHI-PROJECT-17H01420, KAKENHI-PROJECT-18H01836, KAKENHI-PROJECT-19H03499, KAKENHI-PROJECT-18K19287, KAKENHI-PROJECT-18K19298
[Journal Article] Macrocyclic peptide-based inhibition and imaging of hepatocyte growth factor.2019
- Author(s)
  Katsuya Sakai, Toby Passioura, Hiroki Sato, Kenichiro Ito, Hiroki Furuhashi, Masataka Umitsu, Junichi Takagi, Yukinari Kato, Hidefumi Mukai, Shota Warashina, Maki Zouda, Yasuyoshi Watanabe, Seiji Yano, Mikihiro Shibata, Hiroaki Suga, and Kunio Matsumoto
- Journal Title
  
  Nat. Chem. Biol.
  
  Volume: 印刷中
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K19287
[Journal Article] High thermal stability of oligomeric assemblies of Thermophilic rhodopsin in a lipid environment.2018
- Author(s)
  Tomomi Shionoya, Misao Mizuno, Takashi Tsukamoto, Kento Ikeda, Hayato Seki, Keiichi Kojima, Mikihiro Shibata, Izuru Kawamura, Yuki Sudo, and Yasuhisa Mizutani
- Journal Title
  
  J. Phys. Chem. B
  
  Volume: 122 Issue: 27 Pages: 6945-6953
- DOI
  10.1021/acs.jpcb.8b04894
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K19287, KAKENHI-PROJECT-18K14658, KAKENHI-PROJECT-18H01836, KAKENHI-PROJECT-18H02387, KAKENHI-PROJECT-16K13933, KAKENHI-PROJECT-17H01184
[Journal Article] Oligomeric states of microbial rhodopsins determined by high-speed atomic force microscopy and circular dichroic spectroscopy2018
- Author(s)
  Shibata Mikihiro、Inoue Keiichi、Ikeda Kento、Konno Masae、Singh Manish、Kataoka Chihiro、Abe-Yoshizumi Rei、Kandori Hideki、Uchihashi Takayuki
- Journal Title
  
  Scientific Reports
  
  Volume: 8 Issue: 1 Pages: 8262-8262
- DOI
  10.1038/s41598-018-26606-y
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K19230, KAKENHI-PROJECT-18K19287, KAKENHI-PROJECT-18H03986, KAKENHI-PROJECT-18H01836
[Journal Article] Real-space and real-time dynamics of CRISPR-Cas9 visualized by high-speed atomic force microscopy2017
- Author(s)
  Shibata Mikihiro、Nishimasu Hiroshi、Kodera Noriyuki、Hirano Seiichi、Ando Toshio、Uchihashi Takayuki、Nureki Osamu
- Journal Title
  
  Nature Communications
  
  Volume: 8 Issue: 1 Pages: 1430-1430
- DOI
  10.1038/s41467-017-01466-8
- NAID
  120006374160
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K19345, KAKENHI-PUBLICLY-16H00758, KAKENHI-PUBLICLY-16H00830, KAKENHI-PUBLICLY-17H05592, KAKENHI-PROJECT-17H06121, KAKENHI-PROJECT-15H03540, KAKENHI-PROJECT-15H04360, KAKENHI-PROJECT-16K18523
[Journal Article] High-speed atomic force microscopy imaging of live mammalian cells2017
- Author(s)
  Mikihiro Shibata, Hiroki Watanabe, Takayuki Uchihashi, Toshio Ando, and Ryohei Yasuda
- Journal Title
  
  Biophysics and Physicobiology
  
  Volume: 14 Issue: 0 Pages: 127-135
- DOI
  10.2142/biophysico.14.0_127
- NAID
  130005997921
- ISSN
  2189-4779
- Language
  English
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-16H00758, KAKENHI-PUBLICLY-16H00830, KAKENHI-PROJECT-17H06121, KAKENHI-PROJECT-15H03540, KAKENHI-PROJECT-16K18523
[Journal Article] Fast Adsorption of Soft Hydrogel Microspheres on Solid Surfaces in Aqueous Solution2017
- Author(s)
  Matsui Shusuke、Kureha Takuma、Hiroshige Seina、Shibata Mikihiro、Uchihashi Takayuki、Suzuki Daisuke
- Journal Title
  
  Angewandte Chemie International Edition (Communication)
  
  Volume: 56 Issue: 40 Pages: 12146-12149
- DOI
  10.1002/anie.201705808
- NAID
  120006377474
- Peer Reviewed
- Data Source
  KAKENHI-PUBLICLY-16H00758, KAKENHI-PUBLICLY-16H00760, KAKENHI-PUBLICLY-16H00830, KAKENHI-PROJECT-15H03540, KAKENHI-PROJECT-15J11533, KAKENHI-PROJECT-17J05706, KAKENHI-PROJECT-16K18523
[Journal Article] A natural light-driven inward proton pump2016
- Author(s)
  Keiichi Inoue, Shota Ito, Yoshitaka Kato, Yurika Nomura, Mikihiro Shibata, Takayuki Uchihashi, Satoshi P. Tsunoda and Hideki Kandori
- Journal Title
  
  Nature Communications
  
  Volume: 7 Issue: 1 Pages: 13415-13415
- DOI
  10.1038/ncomms13415
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PUBLICLY-16H00758, KAKENHI-PUBLICLY-16H00830, KAKENHI-PLANNED-25104009, KAKENHI-PROJECT-15H02391, KAKENHI-PROJECT-15H03540, KAKENHI-PROJECT-15J06609, KAKENHI-PROJECT-15J06631, KAKENHI-PROJECT-26708001, KAKENHI-PROJECT-26620005, KAKENHI-PROJECT-16K18523
[Patent] 走査型プローブ顕微鏡2016
- Inventor(s)
  内橋貴之、柴田幹大、古寺哲幸
- Industrial Property Rights Holder
  内橋貴之、柴田幹大、古寺哲幸
- Industrial Property Rights Type
  特許
- Industrial Property Number
  2016-234584
- Filing Date
  2016-12-01
- Data Source
  KAKENHI-PROJECT-16K18523
[Presentation] 高速原子間力顕微鏡を用いた１分子ナノ生命科学2022
- Author(s)
  柴田幹大
- Organizer
  第39回分子病理学研究会
- Invited
- Data Source
  KAKENHI-PROJECT-21H01771
[Presentation] Application of high-speed atomic force microscopy to Nano life science2022
- Author(s)
  Mikihiro Shibata
- Organizer
  ナノ精密医学・理工学卓越大学院プログラムプレプログラム,
- Invited
- Data Source
  KAKENHI-PROJECT-21H01771
[Presentation] Direct imaging of spontaneous sliding along DNA of H2A.Z.1 nucleosome by high-speed atomic force microscopy.2022
- Author(s)
  森岡　新, 佐藤祥子, 堀越直樹, 鯨井智也, 胡桃坂仁志, 柴田幹大
- Organizer
  第60回日本生物物理学会年会
- Data Source
  KAKENHI-PROJECT-21H01771
[Presentation] Target DNA binding dynamics of Staphylococcus aureus Cas9 as revealed by high-speed atomic force microscopy.2022
- Author(s)
  Leonardo Puppulin, Junichiro Ishikawa, Hiroshi Nishimasu, Mikihiro Shibata
- Organizer
  第60回日本生物物理学会年会
- Data Source
  KAKENHI-PUBLICLY-21H00247
[Presentation] 高速原子間力顕微鏡を用いたCaMKIIβの動態解析2022
- Author(s)
  松島啓介, 村越秀治, 柴田幹大
- Organizer
  R4年度生物物理学会中部支部講演会
- Data Source
  KAKENHI-PUBLICLY-21H00247
[Presentation] クロマチンリモデリングの実時空間イメージング2022
- Author(s)
  柴田幹大
- Organizer
  新学術領域研究「クロマチン潜在能」第5回領域会議
- Invited
- Data Source
  KAKENHI-PUBLICLY-21H00247
[Presentation] 高速原子間力顕微鏡を用いたCaMKIIβの動態解析2022
- Author(s)
  松島啓介, 村越秀治, 柴田幹大
- Organizer
  R4年度生物物理学会中部支部講演会
- Data Source
  KAKENHI-PROJECT-21H01771
[Presentation] 高速原子間力顕微鏡によるFnCas9の機能動態解析2022
- Author(s)
  塚田秀明, 柴田幹大
- Organizer
  R4年度生物物理学会中部支部講演会
- Data Source
  KAKENHI-PROJECT-21H01771
[Presentation] High-speed atomic force microscopy (HS-AFM) for cancer research2022
- Author(s)
  Mikihiro Shibata
- Organizer
  第81回日本癌学会学術総会
- Invited
- Data Source
  KAKENHI-PROJECT-21H01771
[Presentation] 高速原子間力顕微鏡によるFnCas9の機能動態解析2022
- Author(s)
  塚田秀明, 柴田幹大
- Organizer
  R4年度生物物理学会中部支部講演会
- Data Source
  KAKENHI-PUBLICLY-21H00247
[Presentation] 高速原子間力顕微鏡によるヒストンバリアントのナノ動態観察2022
- Author(s)
  柴田幹大
- Organizer
  第15回日本エピジェネティクス研究会年会
- Invited
- Data Source
  KAKENHI-PUBLICLY-21H00247
[Presentation] 高速原子間力顕微鏡によるヌクレオソームの1 分子ナノ動態撮影2022
- Author(s)
  柴田幹大
- Organizer
  日本顕微鏡学会第78回学術講演会
- Invited
- Data Source
  KAKENHI-PROJECT-21H01771
[Presentation] Target DNA binding dynamics of Staphylococcus aureus Cas9 as revealed by high-speed atomic force microscopy.2022
- Author(s)
  Leonardo Puppulin, Junichiro Ishikawa, Hiroshi Nishimasu, Mikihiro Shibata
- Organizer
  第60回日本生物物理学会年会
- Data Source
  KAKENHI-PROJECT-21H01771
[Presentation] クロマチンリモデリングの実時空間イメージング2022
- Author(s)
  柴田幹大
- Organizer
  新学術領域研究「クロマチン潜在能」第5回領域会議
- Invited
- Data Source
  KAKENHI-PROJECT-21H01771
[Presentation] 原子間力顕微鏡が切り拓くナノ生命科学2022
- Author(s)
  柴田幹大
- Organizer
  がん研究早期体験プログラムがん研EEP 授業編『生命科学・医学研究の最先端と未来』
- Invited
- Data Source
  KAKENHI-PROJECT-21H01771
[Presentation] タンパク質の構造変化をリアルタイムかつナノスケールで可視化する2022
- Author(s)
  柴田幹大
- Organizer
  物性研短期研究会「理論タンパク質物性科学の最前線：理論と実験との密な協働」
- Invited
- Data Source
  KAKENHI-PUBLICLY-21H00247
[Presentation] Oligomeric states of microbial rhodopsins in lipid bilayer determined by high-speed atomic force microscopy2022
- Author(s)
  Mikihiro Shibata and Takayuki Uchihashi
- Organizer
  19th International Conference on Retinal Proteins
- Invited
- Data Source
  KAKENHI-PROJECT-21H01771
[Presentation] 高速AFMによるタンパク質複合体のナノ動態・機能相関の解明2022
- Author(s)
  柴田幹大
- Organizer
  名工大セミナー
- Invited
- Data Source
  KAKENHI-PUBLICLY-21H00247
[Presentation] 高速原子間力顕微鏡を用いた１分子ナノ生命科学2022
- Author(s)
  柴田幹大
- Organizer
  第39回分子病理学研究会
- Invited
- Data Source
  KAKENHI-PUBLICLY-21H00247
[Presentation] Oligomeric states of microbial rhodopsins in lipid bilayer determined by high-speed atomic force microscopy2022
- Author(s)
  Mikihiro Shibata and Takayuki Uchihashi
- Organizer
  19th International Conference on Retinal Proteins
- Invited
- Data Source
  KAKENHI-PUBLICLY-21H00247
[Presentation] 原子間力顕微鏡が切り拓くナノ生命科学2022
- Author(s)
  柴田幹大
- Organizer
  がん研究早期体験プログラムがん研EEP 授業編『生命科学・医学研究の最先端と未来』
- Invited
- Data Source
  KAKENHI-PUBLICLY-21H00247
[Presentation] タンパク質の構造変化をリアルタイムかつナノスケールで可視化する2022
- Author(s)
  柴田幹大
- Organizer
  物性研短期研究会「理論タンパク質物性科学の最前線：理論と実験との密な協働」
- Invited
- Data Source
  KAKENHI-PROJECT-21H01771
[Presentation] 高速原子間力顕微鏡によるヌクレオソームの1 分子ナノ動態撮影2022
- Author(s)
  柴田幹大
- Organizer
  日本顕微鏡学会第78回学術講演会
- Invited
- Data Source
  KAKENHI-PUBLICLY-21H00247
[Presentation] High-speed atomic force microscopy (HS-AFM) for cancer research2022
- Author(s)
  Mikihiro Shibata
- Organizer
  第81回日本癌学会学術総会
- Invited
- Data Source
  KAKENHI-PUBLICLY-21H00247
[Presentation] Correlation between function and mobility of protein complex revealed by HS-AFM2022
- Author(s)
  Mikihiro Shibata
- Organizer
  NanoLSI第6回国際シンポジウム
- Invited
- Data Source
  KAKENHI-PUBLICLY-21H00247
[Presentation] Application of high-speed atomic force microscopy to Nano life science2022
- Author(s)
  Mikihiro Shibata
- Organizer
  ナノ精密医学・理工学卓越大学院プログラムプレプログラム,
- Invited
- Data Source
  KAKENHI-PUBLICLY-21H00247
[Presentation] 高速原子間力顕微鏡によるヒストンバリアントのナノ動態観察2022
- Author(s)
  柴田幹大
- Organizer
  第15回日本エピジェネティクス研究会年会
- Invited
- Data Source
  KAKENHI-PROJECT-21H01771
[Presentation] 高速AFMによるタンパク質複合体のナノ動態・機能相関の解明2022
- Author(s)
  柴田幹大
- Organizer
  名工大セミナー
- Invited
- Data Source
  KAKENHI-PROJECT-21H01771
[Presentation] Direct imaging of spontaneous sliding along DNA of H2A.Z.1 nucleosome by high-speed atomic force microscopy.2022
- Author(s)
  森岡　新, 佐藤祥子, 堀越直樹, 鯨井智也, 胡桃坂仁志, 柴田幹大
- Organizer
  第60回日本生物物理学会年会
- Data Source
  KAKENHI-PUBLICLY-21H00247
[Presentation] Correlation between function and mobility of protein complex revealed by HS-AFM2022
- Author(s)
  Mikihiro Shibata
- Organizer
  NanoLSI第6回国際シンポジウム
- Invited
- Data Source
  KAKENHI-PROJECT-21H01771
[Presentation] 高速AFMによる記憶分子CaMKIIの構造ダイナミクス観察2021
- Author(s)
  柴田幹大
- Organizer
  ブルカージャパン表面計測事業部主催【第２回】高速AFMオンラインシンポジウム
- Invited
- Data Source
  KAKENHI-PUBLICLY-21H00247
[Presentation] ヒストンバリアントH2A.Bによるヌクレオソーム構造変化が転写に与える影響の解明2021
- Author(s)
  赤津綜隆, 平野里奈, 柴田幹大, 鯨井智也, 滝沢由政, 江原晴彦, 関根俊一, 胡桃坂仁志
- Organizer
  第39回染色体ワークショップ・第20回核ダイナミクス研究会
- Data Source
  KAKENHI-PROJECT-21H01771
[Presentation] 高速AFMによる記憶分子CaMKIIの構造ダイナミクス観察2021
- Author(s)
  柴田幹大
- Organizer
  ブルカージャパン表面計測事業部主催【第２回】高速AFMオンラインシンポジウム
- Invited
- Data Source
  KAKENHI-PROJECT-20K21122
[Presentation] Structural dynamics of the cytoplasmic domain of transient receptor potential vanilloid1(TRPV1) in lipid bilayer observed by high speed atomic force microscopy (HS-AFM).2021
- Author(s)
  向大地, Yimeng Zhao, 柴田幹大, 服部素之, 角野歩
- Organizer
  第44回日本分子生物学会年会
- Data Source
  KAKENHI-PUBLICLY-21H00247
[Presentation] 高速原子間力顕微鏡による膜中TRPV1 チャネルの動態観察2021
- Author(s)
  向大地, Yimeng Zhao, 柴田幹大, 服部素之, 角野歩
- Organizer
  第59回日本生物物理学会年会
- Data Source
  KAKENHI-PROJECT-21H01771
[Presentation] Structural dynamics of the cytoplasmic domain of transient receptor potential vanilloid1(TRPV1) in lipid bilayer observed by high speed atomic force microscopy (HS-AFM).2021
- Author(s)
  向大地, Yimeng Zhao, 柴田幹大, 服部素之, 角野歩
- Organizer
  第44回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-20K21122
[Presentation] ヒストンバリアントH2A.Bによるヌクレオソーム構造変化が転写に与える影響の解明2021
- Author(s)
  赤津綜隆, 平野里奈, 柴田幹大, 鯨井智也, 滝沢由政, 江原晴彦, 関根俊一, 胡桃坂仁志
- Organizer
  第39回染色体ワークショップ・第20回核ダイナミクス研究会
- Data Source
  KAKENHI-PUBLICLY-21H00247
[Presentation] クロマチンリモデリングの実時空間イメージング2021
- Author(s)
  柴田幹大
- Organizer
  新学術領域研究「クロマチン潜在能」第4回領域会議
- Invited
- Data Source
  KAKENHI-PROJECT-20K21122
[Presentation] クロマチンリモデリングの実時空間イメージング2021
- Author(s)
  柴田幹大
- Organizer
  新学術領域研究「クロマチン潜在能」第4回領域会議
- Invited
- Data Source
  KAKENHI-PUBLICLY-21H00247
[Presentation] Visualizing single-molecule dynamics of protein complexes by high-speed AFM.2021
- Author(s)
  Mikihiro Shibata
- Organizer
  「全原子・粗視化分子動力学による細胞内分子動態の解明」ウェブセミナー
- Invited
- Data Source
  KAKENHI-PUBLICLY-21H00247
[Presentation] Structural dynamics of the cytoplasmic domain of transient receptor potential vanilloid1(TRPV1) in lipid bilayer observed by high speed atomic force microscopy (HS-AFM).2021
- Author(s)
  向大地, Yimeng Zhao, 柴田幹大, 服部素之, 角野歩
- Organizer
  第44回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-21H01771
[Presentation] Visualizing single-molecule dynamics of protein complexes by high-speed AFM.2021
- Author(s)
  Mikihiro Shibata
- Organizer
  「全原子・粗視化分子動力学による細胞内分子動態の解明」ウェブセミナー
- Invited
- Data Source
  KAKENHI-PROJECT-20K21122
[Presentation] クロマチンリモデリングの実時空間イメージング2021
- Author(s)
  柴田幹大
- Organizer
  新学術領域研究「クロマチン潜在能」第4回領域会議
- Invited
- Data Source
  KAKENHI-PROJECT-21H01771
[Presentation] 高速原子間力顕微鏡による膜中TRPV1 チャネルの動態観察2021
- Author(s)
  向大地, Yimeng Zhao, 柴田幹大, 服部素之, 角野歩
- Organizer
  第59回日本生物物理学会年会
- Data Source
  KAKENHI-PUBLICLY-21H00247
[Presentation] 高速原子間力顕微鏡による膜中TRPV1 チャネルの動態観察2021
- Author(s)
  向大地, Yimeng Zhao, 柴田幹大, 服部素之, 角野歩
- Organizer
  第59回日本生物物理学会年会
- Data Source
  KAKENHI-PROJECT-20K21122
[Presentation] ヒストンバリアントH2A.Bによるヌクレオソーム構造変化が転写に与える影響の解明2021
- Author(s)
  赤津綜隆, 平野里奈, 柴田幹大, 鯨井智也, 滝沢由政, 江原晴彦, 関根俊一, 胡桃坂仁志
- Organizer
  第39回染色体ワークショップ・第20回核ダイナミクス研究会
- Data Source
  KAKENHI-PROJECT-20K21122
[Presentation] 高速AFMによる記憶分子CaMKIIの構造ダイナミクス観察2021
- Author(s)
  柴田幹大
- Organizer
  ブルカージャパン表面計測事業部主催【第２回】高速AFMオンラインシンポジウム
- Invited
- Data Source
  KAKENHI-PROJECT-21H01771
[Presentation] Visualizing single-molecule dynamics of protein complexes by high-speed AFM.2021
- Author(s)
  Mikihiro Shibata
- Organizer
  「全原子・粗視化分子動力学による細胞内分子動態の解明」ウェブセミナー
- Invited
- Data Source
  KAKENHI-PROJECT-21H01771
[Presentation] 高速 AFM によるハブ毒液由来脂質分解酵素 PLA2の膜認識機構の解明2020
- Author(s)
  神谷孫斗, 柴田幹大, 上田直子, 角野歩
- Organizer
  第58回日本生物物理学会年会
- Data Source
  KAKENHI-PUBLICLY-19H05257
[Presentation] 高速AFMを用いたCaMKII多量体のCa2+信号積算メカニズムの解明2020
- Author(s)
  柴田幹大, 村越秀治
- Organizer
  日本生体エネルギー研究会第46回討論会
- Data Source
  KAKENHI-PROJECT-18H01836
[Presentation] 高速 AFM によるハブ毒液由来脂質分解酵素 PLA2の膜認識機構の解明2020
- Author(s)
  神谷孫斗, 柴田幹大, 上田直子, 角野歩
- Organizer
  第58回日本生物物理学会年会
- Data Source
  KAKENHI-PROJECT-20K21122
[Presentation] 高速AFMを用いたCaMKII多量体のCa2+信号積算メカニズムの解明2020
- Author(s)
  柴田幹大, 村越秀治
- Organizer
  日本生体エネルギー研究会第46回討論会
- Data Source
  KAKENHI-PUBLICLY-19H05257
[Presentation] Signal integration mechanism of Ca2+/calmodulin-dependent protein kinase II revealed by High-speed AFM.2020
- Author(s)
  Mikihiro Shibata and Hideji Murakoshi
- Organizer
  BPS2020 64th Annual Meeting
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K19287
[Presentation] 高速原子間力顕微鏡による柔軟なタンパク質動態のナノスケール撮影2020
- Author(s)
  柴田幹大
- Organizer
  第43回日本分子生物学会年会
- Invited
- Data Source
  KAKENHI-PROJECT-18H01836
[Presentation] 高速AFMを用いたCaMKII多量体のCa2+信号積算メカニズムの解明2020
- Author(s)
  柴田幹大, 村越秀治
- Organizer
  日本生体エネルギー研究会第46回討論会
- Data Source
  KAKENHI-PROJECT-20K21122
[Presentation] 高速原子間力顕微鏡による柔軟なタンパク質動態のナノスケール撮影2020
- Author(s)
  柴田幹大
- Organizer
  第43回日本分子生物学会年会
- Invited
- Data Source
  KAKENHI-PUBLICLY-19H05257
[Presentation] Signal integration mechanism of Ca2+/calmodulin-dependent protein kinase II revealed by High-speed AFM.2020
- Author(s)
  Mikihiro Shibata and Hideji Murakoshi
- Organizer
  BPS2020 64th Annual Meeting
- Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-19H05257
[Presentation] 高速原子間力顕微鏡による柔軟なタンパク質動態のナノスケール撮影2020
- Author(s)
  柴田幹大
- Organizer
  第43回日本分子生物学会年会
- Invited
- Data Source
  KAKENHI-PROJECT-20K21122
[Presentation] Signal integration mechanism of Ca2+/calmodulin-dependent protein kinase II revealed by High-speed AFM.2020
- Author(s)
  Mikihiro Shibata and Hideji Murakoshi
- Organizer
  BPS2020 64th Annual Meeting
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18H01836
[Presentation] 高速 AFM によるハブ毒液由来脂質分解酵素 PLA2の膜認識機構の解明2020
- Author(s)
  神谷孫斗, 柴田幹大, 上田直子, 角野歩
- Organizer
  第58回日本生物物理学会年会
- Data Source
  KAKENHI-PROJECT-18H01836
[Presentation] High-speed atomic force microscopy shows conformational dynamics of Ca2+/calmodulin-dependent protein kinase II2019
- Author(s)
  Mikihiro Shibata and Hideji Murakoshi
- Organizer
  BPS19 63th Annual Meeting
- Data Source
  KAKENHI-PROJECT-18K19287
[Presentation] Mapping of mechanical property on live cell surface by scanning ion conductance microscope.2019
- Author(s)
  Satoko Kitazawa, Linhao Sun, Ayako Housaka, Takahiro Watanabe-Nakayama, Hiroki Konno, Mikihiro Shibata, and Shinji Watanabe
- Organizer
  57th日本生物物理学会年会
- Data Source
  KAKENHI-PUBLICLY-19H05257
[Presentation] Application of drift elimination method for high-speed AFM images.2019
- Author(s)
  Shotaro Tsujioka, Hideji Murakoshi, and Mikihiro Shibata
- Organizer
  57th日本生物物理学会年会
- Data Source
  KAKENHI-PROJECT-18K19287
[Presentation] Physicochemical properties of the microbial rhodopsin RxR in the membrane-mimicking molecule styrene maleic acid (SMA) copolymer.2019
- Author(s)
  Tetsuya Ueta, Keiichi Kojima, Tomoya Hino, Mikihiro Shibata, Shingo Nagano & Yuki Sudo
- Organizer
  第11回日本生物物理学会中国四国支部大会
- Data Source
  KAKENHI-PROJECT-18H01836
[Presentation] 計測系から見た分子集合体の機能計測-高速AFM計測2019
- Author(s)
  柴田幹大
- Organizer
  日本化学会第99秋季年会
- Invited
- Data Source
  KAKENHI-PROJECT-18H01836
[Presentation] 高速原子間力顕微鏡によるクロマチン動態のナノスケール観察2019
- Author(s)
  柴田幹大
- Organizer
  第２回クロマチン潜在能領域会議
- Invited
- Data Source
  KAKENHI-PUBLICLY-19H05257
[Presentation] Structure and biophysical characterization of the heliorhodopsin.2019
- Author(s)
  W. Shihoya, K. Inoue, M. Singh, M. Konno, S. Hososhima, K. Yamashita, K. Ikeda, A. Higuchi, S. Okazaki, T. Izume, M. Hashimoto, R. Mizutori, S. Tomida, Y. Yamauchi, R. Abe-Yoshizumi, K. Katayama, S. P.Tsunoda, M. Shibata, Y. Furutani, A. Pushkarev, O. Beja, T. Uchihashi, H. Kandori and O. Nureki
- Organizer
  57th日本生物物理学会年会
- Data Source
  KAKENHI-PROJECT-18K19287
[Presentation] High-speed atomic force microscopy visualization of protein flexibility in action.2019
- Author(s)
  Mikihiro Shibata
- Organizer
  Joint UBI-NanoLSI workshop TRENDS IN MOLECULAR BIOPHYSICS OF LIVING CELLS
- Invited
- Data Source
  KAKENHI-PROJECT-18K19287
[Presentation] Visualizing flexibility in protein structures by high-speed atomic force microscopy.2019
- Author(s)
  Mikihiro Shibata
- Organizer
  57th日本生物物理学会年会
- Invited
- Data Source
  KAKENHI-PROJECT-18K19287
[Presentation] Application of drift elimination method for high-speed AFM images.2019
- Author(s)
  Shotaro Tsujioka, Hideji Murakoshi, and Mikihiro Shibata
- Organizer
  57th日本生物物理学会年会
- Data Source
  KAKENHI-PUBLICLY-19H05257
[Presentation] Nano-scale imaging of biological samples using High-speed Atomic Force Microscopy.2019
- Author(s)
  Mikihiro Shibata
- Organizer
  LIIF2019
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18H01836
[Presentation] Structure and biophysical characterization of the heliorhodopsin.2019
- Author(s)
  W. Shihoya, K. Inoue, M. Singh, M. Konno, S. Hososhima, K. Yamashita, K. Ikeda, A. Higuchi, S. Okazaki, T. Izume, M. Hashimoto, R. Mizutori, S. Tomida, Y. Yamauchi, R. Abe-Yoshizumi, K. Katayama, S. P.Tsunoda, M. Shibata, Y. Furutani, A. Pushkarev, O. Beja, T. Uchihashi, H. Kandori and O. Nureki
- Organizer
  57th日本生物物理学会年会
- Data Source
  KAKENHI-PUBLICLY-19H05257
[Presentation] High-speed atomic force microscopy visualization of protein flexibility in action.2019
- Author(s)
  Mikihiro Shibata
- Organizer
  Joint UBI-NanoLSI workshop TRENDS IN MOLECULAR BIOPHYSICS OF LIVING CELLS
- Invited
- Data Source
  KAKENHI-PROJECT-18H01836
[Presentation] Nano-scale imaging of biological samples using High-speed Atomic Force Microscopy.2019
- Author(s)
  Mikihiro Shibata
- Organizer
  LIIF2019
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-19H05257
[Presentation] 高速原子間力顕微鏡によるクロマチン動態のナノスケール観察2019
- Author(s)
  柴田幹大
- Organizer
  第２回クロマチン潜在能領域会議
- Invited
- Data Source
  KAKENHI-PROJECT-18K19287
[Presentation] Physicochemical properties of the microbial rhodopsin RxR in the membrane-mimicking molecule styrene maleic acid (SMA) copolymer.2019
- Author(s)
  Tetsuya Ueta, Keiichi Kojima, Tomoya Hino, Mikihiro Shibata, Shingo Nagano & Yuki Sudo
- Organizer
  第11回日本生物物理学会中国四国支部大会
- Data Source
  KAKENHI-PROJECT-18K19287
[Presentation] Physicochemical properties of the microbial rhodopsin RxR in the membrane-mimicking molecule styrene maleic acid (SMA) copolymer.2019
- Author(s)
  Tetsuya Ueta, Keiichi Kojima, Tomoya Hino, Mikihiro Shibata, Shingo Nagano & Yuki Sudo
- Organizer
  第11回日本生物物理学会中国四国支部大会
- Data Source
  KAKENHI-PUBLICLY-19H05257
[Presentation] Nano-scale imaging of biological samples using High-speed Atomic Force Microscopy.2019
- Author(s)
  Mikihiro Shibata
- Organizer
  LIIF2019
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K19287
[Presentation] High-speed atomic force microscopy shows conformational dynamics of Ca2+/calmodulin-dependent protein kinase II2019
- Author(s)
  Mikihiro Shibata and Hideji Murakoshi
- Organizer
  BPS19 63th Annual Meeting
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18H01836
[Presentation] High-speed atomic force microscopy visualization of protein flexibility in action.2019
- Author(s)
  Mikihiro Shibata
- Organizer
  Joint UBI-NanoLSI workshop TRENDS IN MOLECULAR BIOPHYSICS OF LIVING CELLS
- Invited
- Data Source
  KAKENHI-PUBLICLY-19H05257
[Presentation] Visualizing flexibility in protein structures by high-speed atomic force microscopy.2019
- Author(s)
  Mikihiro Shibata
- Organizer
  57th日本生物物理学会年会
- Invited
- Data Source
  KAKENHI-PROJECT-18H01836
[Presentation] Mapping of mechanical property on live cell surface by scanning ion conductance microscope.2019
- Author(s)
  Satoko Kitazawa, Linhao Sun, Ayako Housaka, Takahiro Watanabe-Nakayama, Hiroki Konno, Mikihiro Shibata, and Shinji Watanabe
- Organizer
  57th日本生物物理学会年会
- Data Source
  KAKENHI-PROJECT-18H01836
[Presentation] Mapping of mechanical property on live cell surface by scanning ion conductance microscope.2019
- Author(s)
  Satoko Kitazawa, Linhao Sun, Ayako Housaka, Takahiro Watanabe-Nakayama, Hiroki Konno, Mikihiro Shibata, and Shinji Watanabe
- Organizer
  57th日本生物物理学会年会
- Data Source
  KAKENHI-PROJECT-18K19287
[Presentation] 高速原子間力顕微鏡によるクロマチン動態のナノスケール観察2019
- Author(s)
  柴田幹大
- Organizer
  第２回クロマチン潜在能領域会議
- Invited
- Data Source
  KAKENHI-PROJECT-18H01836
[Presentation] Application of drift elimination method for high-speed AFM images.2019
- Author(s)
  Shotaro Tsujioka, Hideji Murakoshi, and Mikihiro Shibata
- Organizer
  57th日本生物物理学会年会
- Data Source
  KAKENHI-PROJECT-18H01836
[Presentation] Structure and biophysical characterization of the heliorhodopsin.2019
- Author(s)
  W. Shihoya, K. Inoue, M. Singh, M. Konno, S. Hososhima, K. Yamashita, K. Ikeda, A. Higuchi, S. Okazaki, T. Izume, M. Hashimoto, R. Mizutori, S. Tomida, Y. Yamauchi, R. Abe-Yoshizumi, K. Katayama, S. P.Tsunoda, M. Shibata, Y. Furutani, A. Pushkarev, O. Beja, T. Uchihashi, H. Kandori and O. Nureki
- Organizer
  57th日本生物物理学会年会
- Data Source
  KAKENHI-PROJECT-18H01836
[Presentation] Visualizing flexibility in protein structures by high-speed atomic force microscopy.2019
- Author(s)
  Mikihiro Shibata
- Organizer
  57th日本生物物理学会年会
- Invited
- Data Source
  KAKENHI-PUBLICLY-19H05257
[Presentation] Visualization of asymmetric structure of Ca2+/calmodulin-dependent protein kinase II oligomers by high-speed atomic force microscopy.2018
- Author(s)
  Mikihiro Shibata, Hideji Murakoshi
- Organizer
  BPS18 62th Annual Meeting
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K18523
[Presentation] Direct imaging of DNA cleavage reaction of CRISPR-Cas9 using high-speed atomic force microscopy.2018
- Author(s)
  Mikihiro Shibata, Hiroshi Nishimasu, Noriyuki Kodera, Seiichi Hirano, Toshio Ando, Takayuki Uchihashi, and Osamu Nureki
- Organizer
  The 1st NanoLSI International Symposium -Towards Establishment of New Research Field: Nanoprobe Life Science-
- Data Source
  KAKENHI-PROJECT-16K18523
[Presentation] 高速原子間力顕微鏡による揺らいだタンパク質構造のナノスケール撮影2018
- Author(s)
  柴田幹大
- Organizer
  非共有結合系の分子科学：計測技術から探る生体分子科学の新展開
- Invited
- Data Source
  KAKENHI-PROJECT-18H01836
[Presentation] Nanoscale visualization of biomolecules using high-speed atomic force microscopy.2018
- Author(s)
  Mikihiro Shibata
- Organizer
  6th AIST International Imaging Workshop
- Invited
- Data Source
  KAKENHI-PROJECT-18H01836
[Presentation] 高速AFMを用いた微生物型ロドプシンの多量体構造の包括的解析2018
- Author(s)
  池田健人, 井上圭一, 今野雅恵, Manish Singh, 片岡千尋, 吉住玲, 神取秀樹, 内橋貴之, 柴田幹大
- Organizer
  平成29年度生物物理学会中部支部講演会
- Data Source
  KAKENHI-PROJECT-16K18523
[Presentation] 高速AFMによるカルモジュリン結合に伴うカルシウム/カルモジュリン依存性プロテインキナーゼIIの動態観察2018
- Author(s)
  辻岡尚太朗, 村越秀治, 柴田幹大
- Organizer
  平成29年度生物物理学会中部支部講演会
- Data Source
  KAKENHI-PROJECT-16K18523
[Presentation] 高速原子間力顕微鏡による生体分子のナノスケールイメージング2018
- Author(s)
  柴田幹大
- Organizer
  2018日本表面真空学会学術講演会
- Invited
- Data Source
  KAKENHI-PROJECT-18K19287
[Presentation] 計測系から見た分子集合体の機能計測-高速AFM計測2018
- Author(s)
  柴田幹大
- Organizer
  日本化学会第99秋季年会複雑系のための分子科学―集まって立ち現れる分子機能の理解と設計
- Invited
- Data Source
  KAKENHI-PROJECT-18K19287
[Presentation] Filming single proteins at work using high-speed atomic force microscopy.2018
- Author(s)
  Mikihiro Shibata
- Organizer
  Irago Conference 2018
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18H01836
[Presentation] High-speed atomic force microscopy for nano-scale imaging of biological samples.2018
- Author(s)
  Mikihiro Shibata
- Organizer
  The 2nd NanoLSI Symposium in London -Towards Establishment of New Research Field: Nanoprobe Life Science-
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18H01836
[Presentation] Watching single proteins in action using high-speed AFM.2018
- Author(s)
  Mikihiro Shibata
- Organizer
  56th生物物理学会年会
- Invited
- Data Source
  KAKENHI-PROJECT-18H01836
[Presentation] 高速原子間力顕微鏡による揺らいだタンパク質構造のナノスケール撮影2018
- Author(s)
  柴田幹大
- Organizer
  非共有結合系の分子科学：計測技術から探る生体分子科学の新展開
- Invited
- Data Source
  KAKENHI-PROJECT-18K19287
[Presentation] 高速原子間力顕微鏡による生体分子のナノスケールイメージング2018
- Author(s)
  柴田幹大
- Organizer
  2018日本表面真空学会学術講演会
- Invited
- Data Source
  KAKENHI-PROJECT-18H01836
[Presentation] Nanoscale imaging of biomolecules by high-speed atomic force microscopy.2018
- Author(s)
  Mikihiro Shibata
- Organizer
  International Symposium on Tumor Biology in Kanazawa Joint Symposium
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18H01836
[Presentation] 高速原子間力顕微鏡によるナノバイオイメージング2017
- Author(s)
  柴田幹大
- Organizer
  第2回新学術創成研究機構シンポジウム
- Place of Presentation
  金沢大学
- Year and Date
  2017-01-26
- Invited
- Data Source
  KAKENHI-PROJECT-16K18523
[Presentation] High-speed AFM visualized DNA cleavage reaction of CRISPR-Cas9.2017
- Author(s)
  Mikihiro Shibata, Hiroshi Nishimasu, Noriyuki Kodera, Seiichi Hirano, Toshio Ando, Takayuki Uchihashi and Osamu Nureki
- Organizer
  International Symposium on Atomic Force Microscopy at Solid-Liquid Interfaces
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K18523
[Presentation] Oligomeric states of microbial rhodopsins studied by high-speed atomic force microscopy.2017
- Author(s)
  Kento Ikeda, Keiichi Inoue, Masae Konno, Rei Abe-Yoshizumi, Chihiro Kataoka, Hideki Kandori, Takayuki Uchihashi, and Mikihiro Shibata
- Organizer
  International Symposium on Atomic Force Microscopy at Solid-Liquid Interfaces
- Data Source
  KAKENHI-PROJECT-16K18523
[Presentation] 高速AFMによる生体分子のナノスケールイメージング2017
- Author(s)
  柴田幹大
- Organizer
  革新的統合バイオ研究コアワークショップ「多様な生命現象の数理モデル研究」
- Invited
- Data Source
  KAKENHI-PROJECT-16K18523
[Presentation] 高速AFMによる生きた細胞のナノスケール観察2017
- Author(s)
  柴田幹大
- Organizer
  第1回生体界面研究会若手の会
- Place of Presentation
  金沢大学
- Year and Date
  2017-02-09
- Invited
- Data Source
  KAKENHI-PROJECT-16K18523
[Presentation] High-speed atomic force microscopy imaging of oligomeric states of microbial rhodopsins.2017
- Author(s)
  Mikihiro Shibata, Takayuki Uchihashi
- Organizer
  International Symposium on Biophysics of Rhodopsin
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K18523
[Presentation] Nanoscale Visualization of Membrane Proteins by High-Speed Atomic Force Microscopy2017
- Author(s)
  Mikihiro Shibata and Takayuki Uchihashi
- Organizer
  日本化学会第97回春季年会
- Place of Presentation
  慶應義塾大学　日吉キャンパス
- Year and Date
  2017-03-16
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K18523
[Presentation] 高速バイオAFMによる生体分子のナノイメージング2017
- Author(s)
  柴田幹大
- Organizer
  金沢大学新学術創成研究機構異分野融合研究会「がん研究と高速バイオAFM」
- Invited
- Data Source
  KAKENHI-PROJECT-16K18523
[Presentation] High-speed AFM imaging of membrane proteins in lipid nanodiscs.2017
- Author(s)
  Mikihiro Shibata
- Organizer
  55th生物物理学会年会
- Invited
- Data Source
  KAKENHI-PROJECT-16K18523
[Presentation] 高速AFMを用いたナノバイオイメージング2017
- Author(s)
  柴田幹大
- Organizer
  理学談話会
- Place of Presentation
  金沢大学
- Year and Date
  2017-02-23
- Invited
- Data Source
  KAKENHI-PROJECT-16K18523
[Presentation] 高速原子間力顕微鏡を用いたカルシウム・カルモジュリン依存性プロテインキナーゼIIのダイナミクス観察2017
- Author(s)
  柴田幹大、村越秀治、内橋貴之
- Organizer
  平成28年度生物物理学会中部支部講演会
- Place of Presentation
  名古屋大学
- Year and Date
  2017-03-06
- Data Source
  KAKENHI-PROJECT-16K18523
[Presentation] 生体分子の動きを観る高速原子間力顕微鏡2017
- Author(s)
  柴田幹大
- Organizer
  自然科学研究機構新分野創成センターシンポジウム「分野横断・分野融合研究による生命創成を探求する新しい科学の創成」
- Invited
- Data Source
  KAKENHI-PROJECT-16K18523
[Presentation] High-speed atomic force microscopy for nano-scale imaging in live cells.2016
- Author(s)
  Mikihiro Shibata
- Organizer
  OptoBioTechnology Symposium on “Membrane Protein Dynamics”
- Place of Presentation
  名古屋工業大学
- Year and Date
  2016-07-12
- Invited
- Data Source
  KAKENHI-PROJECT-16K18523
[Presentation] 高速原子間力顕微鏡によるCRISPR-Cas9のDNA切断作動メカニズムの解明2016
- Author(s)
  柴田幹大, 西増弘志, 古寺哲幸, 平野清一, 濡木理, 内橋貴之
- Organizer
  新学術領域「柔らかな分子系」第4回公開シンポジウム
- Place of Presentation
  名古屋工業大学
- Year and Date
  2016-10-27
- Data Source
  KAKENHI-PROJECT-16K18523
[Presentation] Nanoscale visualization of morphological dynamics of living neurons by high-speed atomic force microscopy.2016
- Author(s)
  Mikihiro Shibata, Takayuki Uchihashi and Toshio Ando
- Organizer
  第８９回日本生化学会大会
- Place of Presentation
  東北大学
- Year and Date
  2016-09-25
- Invited
- Data Source
  KAKENHI-PROJECT-16K18523
[Presentation] Visualization of protein molecules in action by high-speed atomic force microscopy.2016
- Author(s)
  Mikihiro Shibata, Noriyuki Kodera, Takayuki Uchihashi and Toshio Ando
- Organizer
  第５４回日本生物物理学会年会
- Place of Presentation
  つくば国際会議場
- Year and Date
  2016-11-25
- Invited
- Data Source
  KAKENHI-PROJECT-16K18523
[Presentation] カルシウム/カルモジュリン依存性プロテインキナーゼIIの高速原子間力顕微鏡観察2016
- Author(s)
  柴田幹大、村越秀治、内橋貴之
- Organizer
  新学術領域「柔らかな分子系」第５回全体合宿会議
- Place of Presentation
  あてま高原リゾートホテルベルナティオ（新潟県, 十日町）
- Year and Date
  2016-05-30
- Data Source
  KAKENHI-PROJECT-16K18523
[Presentation] 高速AFMを用いたCRISPR/Cas9のDNA切断作動機構の解明2016
- Author(s)
  柴田幹大, 西増弘志, 古寺哲幸, 平野清一, 濡木理, 内橋貴之
- Organizer
  日本生体エネルギー研究会第42回討論会
- Place of Presentation
  名古屋工業大学
- Year and Date
  2016-12-19
- Data Source
  KAKENHI-PROJECT-16K18523
[Presentation] Nanoscale imaging of living cells by high-speed AFM.2016
- Author(s)
  Mikihiro Shibata
- Organizer
  OIIB Retreat 2016
- Place of Presentation
  三河湾リゾートリンクス
- Year and Date
  2016-11-21
- Invited
- Data Source
  KAKENHI-PROJECT-16K18523

1. Nishimasu Hiroshi (00467044)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
2. NUREKI Osamu (10272460)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
3. SIOMI Mikiko (20322745)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
4. SIOMI Haruhiko (60202107)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
5. KODERA Noriyuki (30584635)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
6. Zhang Feng

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. 角田聡

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
8. 梅田健一

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
9. 佐藤拓輝

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
10. 内橋貴之

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
11. 松本邦夫

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
12. 角野歩

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
13. 井上雅恵

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Shibata Mikihiro 柴田 幹大

Research Projects

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Co-Researchers

Real-space and real-time visualization of histone tails by single-molecule imagingPrincipal Investigator

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Real-time and real-space imaging of chromatin remodelingPrincipal Investigator

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Investigation of molecular insight into genome editing tools by single-molecule imagingPrincipal Investigator

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Challenge to elucidate the molecular mechanism of memory by single molecule imagingPrincipal Investigator

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Real-time and real-space imaging of chromatin dynamicsPrincipal Investigator

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Challenge to near atomic resolution AFM image by fusion of high-speed AFM and advanced image analysisPrincipal Investigator

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Comprehensive studies of working mechanism of Cas proteins using HS-AFMPrincipal Investigator

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HS-AFM studies of molecular mechanisms of learning and memory in CaMKII oligomerPrincipal Investigator

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Elucidation of molecular mechanisms of RNA silencing

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[Journal Article] High-Speed Atomic Force Microscopy Reveals Spontaneous Nucleosome Sliding of H2A.Z at the Subsecond Time Scale2023

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[Journal Article] Dynamics of Target DNA Binding and Cleavage by Staphylococcus aureus Cas9 as Revealed by High-Speed Atomic Force Microscopy2023

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[Journal Article] Designing receptor agonists with enhanced pharmacokinetics by grafting macrocyclic peptides into fragment crystallizable regions2022

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[Journal Article] Histone variant H2A.B-H2B dimers are spontaneously exchanged with canonical H2A-H2B in the nucleosome2021

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NAID

Data Source

[Journal Article] Macrocyclic Peptide-Conjugated Tip for Fast and Selective Molecular Recognition Imaging by High-Speed Atomic Force Microscopy2021

Shibata Mikihiro 柴田幹大