Ishifune Chieko 石舟智恵子

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ISHIFUNE Chieko 石舟智恵子

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Researcher Number	80632645
Other IDs
Affiliation (Current)	2025: 徳島大学, 大学院医歯薬学研究部(医学域), 助教
Affiliation (based on the past Project Information) *help	2018 – 2023: 徳島大学, 大学院医歯薬学研究部(医学域), 助教 2016 – 2017: 徳島大学, 大学院医歯薬学研究部(医学系), 助教 2015: 徳島大学, 大学院医歯薬学研究部, 助教 2012: 徳島大学, ヘルスバイオサイエンス研究部, 助教 2012: 徳島大学, 大学院・ヘルスバイオサイエンス研究部, 助教
Review Section/Research Field	Principal Investigator Basic Section 49070:Immunology-related / Immunology
Keywords	Principal Investigator Notchシグナル / 腸管上皮間リンパ球 / シングルセル解析 / 多様性 / TCRレパトア / Nochシグナル / 成熟 / フリッパーゼ / マクロファージ / フリッパーセ … More / 上皮間リンパ球 / 粘膜免疫応答 / 粘膜固有層 / 小腸 / 分化 / 粘膜免疫 / 抗原提示細胞 Less

Elucidation of the mechanism of Notch-mediated acquisition of interepithelial lymphocyte diversity in the small intestine using single-cell analysis technologyPrincipal Investigator
- Principal Investigator
  
  石舟智恵子
- Project Period (FY)
  2023 – 2027
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 49070:Immunology-related
- Research Institution
  The University of Tokushima
Elucidation of the regulation mechanisms of maturation and TCR repertoire of small intestinal interepithelial lymphocytes by Notch signalingPrincipal Investigator
- Principal Investigator
  
  ISHIFUNE Chieko
- Project Period (FY)
  2018 – 2022
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 49070:Immunology-related
- Research Institution
  The University of Tokushima
Elucidation of maintenance mechanism of intestinal homeostasis through control of small intestinal epithelial lymphocytes by Notch signalPrincipal Investigator
- Principal Investigator
  
  ISHIFUNE Chieko
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Immunology
- Research Institution
  The University of Tokushima
Regulation of differentiation of the small intestinal lamina proprial CX3CR1-positive cells by the Notch signal.Principal Investigator
- Principal Investigator
  
  ISHIFUNE Chieko
- Project Period (FY)
  2012
- Research Category
  
  Grant-in-Aid for Research Activity Start-up
- Research Field
  
  Immunology
- Research Institution
  The University of Tokushima

All 2023 2022 2019 2018 2017 2016 2015 2012 Other

All Journal Article Presentation Book

[Book] Notch signaling Immunity and Cancer-Notch and Myeloid Cells-2017
- Author(s)
  Chieko Ishifune and Koji Yasutomo
- Total Pages
  104
- Publisher
  Springer
- ISBN
  9789811049705
- Data Source
  KAKENHI-PROJECT-15K19131
[Book] 別冊　医学のあゆみレドックスUPDATE ストレス制御の臨床医学・健康科学2015
- Author(s)
  石舟智恵子　安友康二
- Total Pages
  6
- Publisher
  医歯薬出版株式会社
- Data Source
  KAKENHI-PROJECT-15K19131
[Book] 臨床免疫・アレルギー科2012
- Author(s)
  石舟智恵子　他
- Publisher
  科学評論社
- Data Source
  KAKENHI-PROJECT-24890146
[Book] 細胞工学2012
- Author(s)
  石舟智恵子　他
- Publisher
  秀潤社
- Data Source
  KAKENHI-PROJECT-24890146
[Book] 細胞工学2012
- Author(s)
  石舟智恵子、安友康二
- Publisher
  秀潤社
- Data Source
  KAKENHI-PROJECT-24890146
[Book] 臨床免疫・アレルギー科2012
- Author(s)
  石舟智恵子、安友康二
- Publisher
  科学評論社
- Data Source
  KAKENHI-PROJECT-24890146
[Journal Article] Stimulation of the farnesoid X receptor promotes M2 macrophage polarization2023
- Author(s)
  Jaroonwitchawan Thiranut、Arimochi Hideki、Sasaki Yuki、Ishifune Chieko、Kondo Hiroyuki、Otsuka Kunihiro、Tsukumo Shin-ichi、Yasutomo Koji
- Journal Title
  
  Frontiers in Immunology
  
  Volume: 14 Pages: 1065790-1065800
- DOI
  10.3389/fimmu.2023.1065790
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K15495, KAKENHI-PROJECT-18K15191, KAKENHI-PROJECT-20K18479, KAKENHI-PROJECT-23K06585
[Journal Article] AFF3, a susceptibility factor for autoimmune diseases, is a molecular facilitator of immunoglobulin class switch recombination2022
- Author(s)
  Tsukumo Shin-ichi、Subramani Poorani Ganesh、Seija Noe、Tabata Mizuho、Maekawa Yoichi、Mori Yuya、Ishifune Chieko、Itoh Yasushi、Ota Mineto、Fujio Keishi、Di Noia Javier M.、Yasutomo Koji
- Journal Title
  
  Science Advances
  
  Volume: 8 Issue: 34 Pages: 1-15
- DOI
  10.1126/sciadv.abq0008
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21H02960, KAKENHI-PROJECT-18K15191, KAKENHI-PROJECT-20H03478
[Journal Article] Regulation of membrane phospholipid asymmetry by Notch-mediated flippase expression controls the number of intraepithelial TCRαβ+CD8αα+ T cells.2019
- Author(s)
  Ishifune C, Tsukumo S, Maekawa Y, Hozumi K, Chung D, Motozono C, Yamasaki S, Nakano H, Yasutomo K.
- Journal Title
  
  PLoS Biology
  
  Volume: - Issue: 5 Pages: e3000262-e3000262
- DOI
  10.1371/journal.pbio.3000262
- NAID
  120006812006
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-26110003, KAKENHI-PROJECT-17H04069, KAKENHI-PROJECT-17K19533, KAKENHI-PROJECT-19K07623, KAKENHI-PROJECT-18K15191, KAKENHI-PROJECT-17H04087
[Journal Article] MicroRNA-449a deficiency promotes colon carcinogenesis2017
- Author(s)
  Niki Masanori、Nakajima Kohei、Ishikawa Daichi、Nishida Jun、Ishifune Chieko、Tsukumo Shin-ichi、Shimada Mitsuo、Nagahiro Shinji、Mitamura Yoshinori、Yasutomo Koji
- Journal Title
  
  Scientific Reports
  
  Volume: 7（1） Issue: 1 Pages: 10696-10696
- DOI
  10.1038/s41598-017-10500-0
- NAID
  120006535013
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16H07015, KAKENHI-PROJECT-15K08307, KAKENHI-PROJECT-15K19131
[Journal Article] Notch Balances Th17 and Induced Regulatory T Cell Functions in Dendritic Cells by RegulatingAldh1a2Expression2017
- Author(s)
  Zaman Taskia Sultana、Arimochi Hideki、Maruyama Satoshi、Ishifune Chieko、Tsukumo Shin-ichi、Kitamura Akiko、Yasutomo Koji
- Journal Title
  
  The Journal of Immunology
  
  Volume: 199 Issue: 6 Pages: 1989-1997
- DOI
  10.4049/jimmunol.1700645
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-26110008, KAKENHI-PROJECT-15K19131
[Journal Article] Transmission of survival signals through Delta-like 1 on activated CD4+ T cells2016
- Author(s)
  Furukawa T, Ishifune C, Tsukumo S, Hozumi K, Maekawa Y, Matsui N, Kaji R, Yasutomo K
- Journal Title
  
  Scientific Reports
  
  Volume: 6 Issue: 1 Pages: 33692-33692
- DOI
  10.1038/srep33692
- NAID
  120006534968
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H04724, KAKENHI-PROJECT-26450401, KAKENHI-PROJECT-15K19131, KAKENHI-PROJECT-16K15524
[Journal Article] Regulation of monocyte cell fate by blood vessels mediated by Notch signalling.2016
- Author(s)
  Gamrekelashvili J, Giagnorio R, Jussofie J, Soehnlein O, Duchene J, Briseno CG, Ramasamy SK, Krishnasamy K, Limbourg A, Kapanadze T, Ishifune C, Hinkel R, Radtke F, Strobl LJ, Zimber-Strobl U, Napp LC, Bauersachs J, Haller H, Yasutomo K, Kupatt C, Murphy KM, Adams RH, Weber C, Limbourg FP
- Journal Title
  
  Nature Communications
  
  Volume: 7 Issue: 1
- DOI
  10.1038/ncomms12597
- NAID
  120006535058
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K19131
[Journal Article] Notch controls the persistence of autoimmune memory CD4+ T cells by maintaining glucose uptake.2015
- Author(s)
  Maekawa Y, Ishifune C, Tsukumo S, Hozumi K, Yagita H, Yasutomo K.
- Journal Title
  
  Nature Medicine
  
  Volume: 21 Issue: 1 Pages: 55-61
- DOI
  10.1038/nm.3758
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24590585, KAKENHI-PROJECT-26290059, KAKENHI-PROJECT-15K19131, KAKENHI-PLANNED-26110008, KAKENHI-PROJECT-26253063
[Journal Article] CD98 heavy chain Is a potent positive regulator of CD4+ T cell proliferation and interferon-γ production in vivo.2015
- Author(s)
  Kurihara T, Arimochi H, Bhuyan ZA, Ishifune C, Tsumura H, Ito M, Ito Y, Kitamura A, Maekawa Y, YasutomoK.
- Journal Title
  
  PLoS One
  
  Volume: 10 Issue: 10 Pages: e0139692-e0139692
- DOI
  10.1371/journal.pone.0139692
- NAID
  120006871194
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15K19131, KAKENHI-PROJECT-15H04724
[Journal Article] Notch 1 and Notch 2 synergistically regulate the differentiation and function of invariant NKT cells.2015
- Author(s)
  Oh SJ, Ahn S, Jin YH, Ishifune C, Kim JH, Yasutomo K, and Chung DH.
- Journal Title
  
  Journal of Leukocyte Biology
  
  Volume: 98 Issue: 5 Pages: 781-789
- DOI
  10.1189/jlb.1a0914-459rr
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K19131
[Journal Article] Notch2 regulates the development of marginal zone B cells through Fos2012
- Author(s)
  Iwahashi S, Maekawa Y, Nishida J, Ishifune C, Kitamura A, Arimochi H, Kataoko K, Chiba S, Shimada M, Yasutomo K
- Journal Title
  
  iochem Biophys Res Commun
  
  Volume: 418 Issue: 4 Pages: 701-707
- DOI
  10.1016/j.bbrc.2012.01.082
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20679005, KAKENHI-PROJECT-23390324, KAKENHI-PROJECT-23500958, KAKENHI-PROJECT-23791179, KAKENHI-PROJECT-24890146
[Presentation] Notch signal controls final differentiation of TCRγδ+CD8αα+ intraepithelial lymphocytes in the small intestine2022
- Author(s)
  石舟智恵子　安友康二
- Organizer
  第51回日本免疫学会学術集会
- Data Source
  KAKENHI-PROJECT-18K15191
[Presentation] Notch-mediated final differantiation of TCRgd+CD8aa+ intraepithelial lymphocyte in the small intestine2018
- Author(s)
  Chieko Ishifune and Koji Yasutomo
- Organizer
  The 47th Annual Meeting of The Japanease Society for Immunology
- Data Source
  KAKENHI-PROJECT-18K15191
[Presentation] Notch signal controls the number of TCRab+CD8aa+ intraepithelial lymphocytes via phospholipid asymmetry by maintaining flippase ATP8a22017
- Author(s)
  Chieko Ishifune, Yoichi Maekawa, Shin-ichi Tsukumo and Koji Yasutomo
- Organizer
  第46回日本免疫学会学術集会
- Data Source
  KAKENHI-PROJECT-15K19131
[Presentation] Notchシグナルによる細胞膜リン脂質の極性制御を介した腸管上皮間リンパ球の制御2017
- Author(s)
  石舟智恵子, 安友康二
- Organizer
  第32回自己免疫研究会
- Data Source
  KAKENHI-PROJECT-15K19131
[Presentation] Notch-Rbpj controls TCR alpha beta+ CD8 alpha alpha+ intraepithelial lymphocytes by maintaining fllipase ATP8a22016
- Author(s)
  Chieko Ishifune, Yoichi Maekawa, Shin-ichi Tsukumo and Koji Yasutomo
- Organizer
  第45回日本免疫学会学術集会
- Place of Presentation
  沖縄コンベンションセンター（沖縄県宜野湾市）
- Year and Date
  2016-12-05
- Data Source
  KAKENHI-PROJECT-15K19131
[Presentation] Notch-STAT5b is central for the development of TCR alpha beta+ CD8 alpha alpha+ small intestinal intraepithelial lymphocytes2016
- Author(s)
  Chieko Ishifune, Yoichi Maekawa, Katsuto Hozumi and Koji Yasutomo
- Organizer
  16th International Congress of Immunology (ICI)
- Place of Presentation
  メルボルン（オーストラリア）
- Year and Date
  2016-08-24
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K19131
[Presentation] Notch-STAT5b is central for the differentiation of TCR alpha beta+ CD8 alpha alpha+ intraepithelial lymphocytes.2015
- Author(s)
  Chieko Ishifune, Yoichi Maekowa, Katsuto Hozumi and Koji Yasutomo
- Organizer
  第44回日本免疫学会総会・学術集会
- Place of Presentation
  札幌コンベンションセンター（北海道札幌市）
- Year and Date
  2015-11-20
- Data Source
  KAKENHI-PROJECT-15K19131
[Presentation] Notch-STAT5b Signaling Regulates the TCR alpha beta+ CD8 alpha alpha+ Intraepithelial Lymphocytes in the Small Intestine,2015
- Author(s)
  Chieko Ishifune and Koji Yasutomo
- Organizer
  17th International Congress of Mucosal Immunology
- Place of Presentation
  Maritim Hotel Berlin　(ベルリン、ドイツ）
- Year and Date
  2015-07-16
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K19131
[Presentation] Notch signaling is essential for the differentiation ofCX3CR1-positive cell in lamina propria of the small intestine.2012
- Author(s)
  石舟智恵子、前川洋一、安友康二
- Organizer
  国際樹状細胞学会
- Place of Presentation
  EXCO (Daegu Exhibition & Convention Center)(韓国、テグ)
- Year and Date
  2012-10-07
- Data Source
  KAKENHI-PROJECT-24890146
[Presentation] NotchシグナルはCX3CR1陽性小腸粘膜固有層細胞の分化に必須である、2012
- Author(s)
  石舟智恵子、前川洋一、安友康二
- Organizer
  日本免疫学会総会学術集会
- Place of Presentation
  神戸国際会議場(神戸市)
- Year and Date
  2012-12-05
- Data Source
  KAKENHI-PROJECT-24890146
[Presentation] Notch signaling is essential for the differentiation of CX3CR1-positive cell in lamina propria of the small intestine.
- Author(s)
  石舟智恵子
- Organizer
  国際樹状細胞学会
- Place of Presentation
  EXCO (Daegu Exhibition & Convention Center)、テグ、韓国
- Data Source
  KAKENHI-PROJECT-24890146
[Presentation] NotchシグナルはCX3CR1陽性小腸粘膜固有層細胞の分化に必須である
- Author(s)
  石舟智恵子
- Organizer
  日本免疫学会総会学術集会
- Place of Presentation
  神戸国際会議場、兵庫県
- Data Source
  KAKENHI-PROJECT-24890146

1. YASUTOMO Koji (30333511)

# of Collaborated Projects: 1 results

# of Collaborated Products: 13 results
2. FUJIO Keishi

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
3. 前川洋一

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
4. 石川大地

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
5. 近藤博之

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
6. 中野裕康

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Ishifune Chieko 石舟 智恵子

ISHIFUNE Chieko 石舟 智恵子

Research Projects

Research Products

Co-Researchers

Elucidation of the mechanism of Notch-mediated acquisition of interepithelial lymphocyte diversity in the small intestine using single-cell analysis technologyPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Elucidation of the regulation mechanisms of maturation and TCR repertoire of small intestinal interepithelial lymphocytes by Notch signalingPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Elucidation of maintenance mechanism of intestinal homeostasis through control of small intestinal epithelial lymphocytes by Notch signalPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Regulation of differentiation of the small intestinal lamina proprial CX3CR1-positive cells by the Notch signal.Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Book] Notch signaling Immunity and Cancer-Notch and Myeloid Cells-2017

Author(s)

Total Pages

Publisher

ISBN

Data Source

[Book] 別冊 医学のあゆみ レドックスUPDATE ストレス制御の臨床医学・健康科学2015

Author(s)

Total Pages

Publisher

Data Source

[Book] 臨床免疫・アレルギー科2012

Author(s)

Publisher

Data Source

[Book] 細胞工学2012

Author(s)

Publisher

Data Source

[Book] 細胞工学2012

Author(s)

Publisher

Data Source

[Book] 臨床免疫・アレルギー科2012

Author(s)

Publisher

Data Source

[Journal Article] Stimulation of the farnesoid X receptor promotes M2 macrophage polarization2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] AFF3, a susceptibility factor for autoimmune diseases, is a molecular facilitator of immunoglobulin class switch recombination2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Regulation of membrane phospholipid asymmetry by Notch-mediated flippase expression controls the number of intraepithelial TCRαβ+CD8αα+ T cells.2019

Author(s)

Journal Title

DOI

NAID

Data Source

[Journal Article] MicroRNA-449a deficiency promotes colon carcinogenesis2017

Author(s)

Journal Title

DOI

NAID

Data Source

[Journal Article] Notch Balances Th17 and Induced Regulatory T Cell Functions in Dendritic Cells by RegulatingAldh1a2Expression2017

Author(s)

Ishifune Chieko 石舟智恵子

ISHIFUNE Chieko 石舟智恵子

[Book] 別冊　医学のあゆみレドックスUPDATE ストレス制御の臨床医学・健康科学2015