SASAKI NORIHIKO 佐々木紀彦

… Alternative Names

SASAKI Norihiko 佐々木紀彦

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Researcher Number	80639063
Other IDs
Affiliation (Current)	2025: 地方独立行政法人東京都健康長寿医療センター(東京都健康長寿医療センター研究所), 東京都健康長寿医療センター研究所, 准主任研究員
Affiliation (based on the past Project Information) *help	2025: 地方独立行政法人東京都健康長寿医療センター(東京都健康長寿医療センター研究所), 東京都健康長寿医療センター研究所, 准主任研究員 2016 – 2023: 地方独立行政法人東京都健康長寿医療センター(東京都健康長寿医療センター研究所), 東京都健康長寿医療センター研究所, 研究員 2013: 地方独立行政法人東京都健康長寿医療センター(東京都健康長寿医療センター研究所), その他部局等, 研究員 2013: 地方独立行政法人東京都健康長寿医療センター(東京都健康長寿医療センター研究所), 東京都健康長寿医療センター研究所, 研究員 2012: 独立行政法人国立成育医療研究センター, その他部局等, その他
Review Section/Research Field	Principal Investigator Basic Section 59040:Nutrition science and health science-related / Biological pharmacy / Experimental pathology Except Principal Investigator Basic Section 55020:Digestive surgery-related / Medium-sized Section 58:Society medicine, nursing, and related fields / Gerontological nursing
Keywords	Principal Investigator 老化 / 血管内皮細胞 / へパラン硫酸脱硫酸化酵素 / ガングリオシド / 内皮細胞 / ラパマイシン / 心血管病 / KOマウス / 糖鎖修飾 / NFκB … More / 老化血管内皮細胞由来因子 / 細胞間ネットワーク / 心血管 / ヘパラン硫酸脱硫酸化酵素 / 形質転換 / 平滑筋細胞 / 細胞老化 / バイオマーカー / 内皮機能 / 加齢/老化 / インスリン抵抗 / ガングリオシドGM1 / 接着性 / 透過性 / 糖脂質 / 内皮間葉転換 / オートファジー / SASP / インスリン抵抗性 / GM1ガングリオシド / TNFα / 炎症 / 分化誘導 / ヒトiPS細胞 / ストレス性老化 / 自然細胞老化 / iPS細胞 / 糖鎖 / 加齢 … More Except Principal Investigator 糖鎖 / 膵癌 / 癌幹細胞 / E-cadherin / がん幹細胞 / 再生 / 幹細胞 / 心筋梗塞 / 培養細胞株 / 遊走能 / 膵星細胞 / 3次元培養 / 上皮間葉系形質 / 消化管 / 神経内分泌腫瘍 / EMT / 位相差顕微鏡 / 走査型電子顕微鏡 / 消化管神経内分泌腫瘍 / 3D培養 / 組織再生 / 加齢 / 栄養 / 心疾患 / 免疫 / 炎症 / 評価 / 間葉系幹細胞 / 多様性 / geneticin / 発現細胞 / 表面糖鎖 / 細胞表面糖鎖 / nestin / 膵癌細胞 / シングルセル解析 / プロテオーム解析 / Vimentin / SEM / スフェア / 膵臓がん / 質量分析 / 大腸がん / リン脂質 / がん転移 / エクソーム解析 / SNP / Nestin / 切片 / 細胞培養 / モデルマウス Less

血管内皮細胞由来の細胞外スルファターゼによる老化関連疾患の発症・重症化機構の解明Principal Investigator
- Principal Investigator
  
  佐々木紀彦
- Project Period (FY)
  2025 – 2027
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 59040:Nutrition science and health science-related
- Research Institution
  Tokyo Metropolitan Institute for Geriatrics and Gerontology
へパラン硫酸脱硫酸化酵素を標的とした老化関連疾患の予防・治療法の開発Principal Investigator
- Principal Investigator
  
  佐々木紀彦
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 59040:Nutrition science and health science-related
- Research Institution
  Tokyo Metropolitan Geriatric Hospital and Institute of Gerontology
Molecular biological analysis of gastrointestinal neuroendocrine tumors and development of new therapeutic drugs
- Principal Investigator
  
  進士誠一
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 55020:Digestive surgery-related
- Research Institution
  Nippon Medical School
Development of novel therapies by regulating epithelial and mesenchymal features of pancreatic cancer
- Principal Investigator
  
  石渡俊行
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 55020:Digestive surgery-related
- Research Institution
  Tokyo Metropolitan Geriatric Hospital and Institute of Gerontology
New therapeutic methods by variability control of pancreatic cancer cells
- Principal Investigator
  
  志智優樹
- Project Period (FY)
  2021 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 55020:Digestive surgery-related
- Research Institution
  Tokyo Metropolitan Geriatric Hospital and Institute of Gerontology
幹細胞表面特異的糖鎖を標的とした膵癌の新規治療法の開発
- Principal Investigator
  
  五味不二也
- Project Period (FY)
  2021 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 55020:Digestive surgery-related
- Research Institution
  Tokyo Metropolitan Geriatric Hospital and Institute of Gerontology
Effects of nutrition, aging, and stem cell against inflammation on high-risk heart disease, and evaluation of tissue regeneration ability.
- Principal Investigator
  
  千葉由美
- Project Period (FY)
  2021 – 2024
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Review Section
  
  Medium-sized Section 58:Society medicine, nursing, and related fields
- Research Institution
  Yokohama City University
Regulation of colorectal cancer metastasis by fatty acid remodeling enzymes involved in glycerophospholipid metabolism
- Principal Investigator
  
  佐々木洋子
- Project Period (FY)
  2020 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 55020:Digestive surgery-related
- Research Institution
  Teikyo University
Development of early diagnosis and new treatments for pancreatic cancer using cancer stem cell-specific glycans
- Principal Investigator
  
  Ishiwata Toshiyuki
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 55020:Digestive surgery-related
- Research Institution
  Tokyo Metropolitan Geriatric Hospital and Institute of Gerontology
Elucidation of the cardiovascular network mechanism mediated by senescent vascular endothelial cell-derived factorsPrincipal Investigator
- Principal Investigator
  
  Sasaki Norihiko
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 59040:Nutrition science and health science-related
- Research Institution
  Tokyo Metropolitan Geriatric Hospital and Institute of Gerontology
Basic research for the development of new preventive and therapeutic methods for vascular diseases targeting GM1Principal Investigator
- Principal Investigator
  
  Sasaki Norihiko
- Project Period (FY)
  2016 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Biological pharmacy
- Research Institution
  Tokyo Metropolitan Geriatric Hospital and Institute of Gerontology
Influence of aging and exercise on engraftment after stem cell transplantation into myocardial infarction model mice
- Principal Investigator
  
  CHIBA Yumi
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Gerontological nursing
- Research Institution
  Yokohama City University
The clarification of functional roles of glycoconjugates in onset of age- and senescence-related diseasesPrincipal Investigator
- Principal Investigator
  
  SASAKI Norihiko
- Project Period (FY)
  2012 – 2013
- Research Category
  
  Grant-in-Aid for Research Activity Start-up
- Research Field
  
  Experimental pathology
- Research Institution
  Tokyo Metropolitan Geriatric Hospital and Institute of Gerontology
  National Research Institute for Child Health and Development

All 2024 2023 2022 2021 2020 2019 2018 2017 2016 2015 2014 2013

All Journal Article Presentation Book Patent

[Book] “細胞老化と糖鎖”, 基礎老化研究誌2022
- Author(s)
  佐々木紀彦
- Total Pages
  9
- Publisher
  日本基礎老化学会
- Data Source
  KAKENHI-PROJECT-19K11759
[Book] 病理アトラス老化と糖鎖研究2021
- Author(s)
  佐々木紀彦
- Total Pages
  5
- Publisher
  別冊BIO Clinica (北隆館)
- Data Source
  KAKENHI-PROJECT-19K11759
[Book] 老化関連疾患の予防、治療法の開発に向けた『老化と糖鎖』2018
- Author(s)
  佐々木紀彦、板倉陽子、豊田雅士
- Total Pages
  5
- Publisher
  日本生化学会
- Data Source
  KAKENHI-PROJECT-16K08263
[Journal Article] Spatiotemporal changes of tissue glycans depending on localization in cardiac aging2023
- Author(s)
  Itakura Yoko、Hasegawa Yasuko、Kikkawa Yurika、Murakami Yuina、Sugiura Kosuke、Nagai-Okatani Chiaki、Sasaki Norihiko、Umemura Mariko、Takahashi Yuji、Kimura Tohru、Kuno Atsushi、Ishiwata Toshiyuki、Toyoda Masashi
- Journal Title
  
  Regenerative Therapy
  
  Volume: 22 Pages: 68-78
- DOI
  10.1016/j.reth.2022.12.009
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K11666, KAKENHI-PROJECT-22K06046, KAKENHI-PROJECT-20K17136, KAKENHI-PROJECT-21K19754, KAKENHI-PROJECT-22K11794
[Journal Article] Expression and Distribution of GPR55, a Receptor for Lysophosphatidylinositol, in Mouse Tissues and Cells2022
- Author(s)
  Tanikawa Takashi、Oka Saori、Nakajima Keisuke、Hayashi Yasuhiro、Nemoto-Sasaki Yoko、Arata Yoichiro、Sugiura Takayuki、Yamashita Atsushi
- Journal Title
  
  BPB Reports
  
  Volume: 5 Issue: 2 Pages: 16-20
- DOI
  10.1248/bpbreports.5.2_16
- ISSN
  2434-432X
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K09066, KAKENHI-PROJECT-22K06584
[Journal Article] Gp130-Mediated STAT3 Activation Contributes to the Aggressiveness of Pancreatic Cancer through H19 Long Non-Coding RNA Expression2022
- Author(s)
  Sasaki Norihiko、Hirano Kazumi、Shichi Yuuki、Gomi Fujiya、Yoshimura Hisashi、Matsushita Akira、Toyoda Masashi、Ishiwata Toshiyuki
- Journal Title
  
  Cancers
  
  Volume: 14 Issue: 9 Pages: 2055-2055
- DOI
  10.3390/cancers14092055
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K09207, KAKENHI-PROJECT-21K08744, KAKENHI-PROJECT-21K08764, KAKENHI-PROJECT-22K06013, KAKENHI-PROJECT-18K14597
[Journal Article] Lysophosphatidylinositol Induced Morphological Changes and Stress Fiber Formation through the GPR55-RhoA-ROCK Pathway2022
- Author(s)
  Nakajima Keisuke、Oka Saori、Tanikawa Takashi、Nemoto-Sasaki Yoko、Matsumoto Naoki、Ishiguro Hiroki、Arata Yoichiro、Sugiura Takayuki、Yamashita Atsushi
- Journal Title
  
  International Journal of Molecular Sciences
  
  Volume: 23 Issue: 18 Pages: 10932-10932
- DOI
  10.3390/ijms231810932
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K09066, KAKENHI-PROJECT-21K11636, KAKENHI-PROJECT-22K06584
[Journal Article] Epithelial and Mesenchymal Features of Pancreatic Ductal Adenocarcinoma Cell Lines in Two- and Three-Dimensional Cultures2022
- Author(s)
  Shichi Yuuki、Gomi Fujiya、Sasaki Norihiko、Nonaka Keisuke、Arai Tomio、Ishiwata Toshiyuki
- Journal Title
  
  Journal of Personalized Medicine
  
  Volume: 12 Issue: 5 Pages: 746-746
- DOI
  10.3390/jpm12050746
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K09207, KAKENHI-PROJECT-21K08744, KAKENHI-PROJECT-21K08764
[Journal Article] Phosphorylation and subcellular localization of human phospholipase A1, DDHD1/PA-PLA12022
- Author(s)
  Yamashita Atsushi、Matsumoto Naoki、Nemoto-Sasaki Yoko、Oka Saori、Arai Seisuke、Wada Ikuo
- Journal Title
  
  Methods in Enzymology
  
  Volume: 675 Pages: 235-273
- DOI
  10.1016/bs.mie.2022.07.011
- ISBN
  9780323992664
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K09066, KAKENHI-PROJECT-21K05508, KAKENHI-PROJECT-21K11636, KAKENHI-PROJECT-22K06584
[Journal Article] TGF-β1 increases cellular invasion of colorectal neuroendocrine carcinoma cell line through partial epithelial-mesenchymal transition2022
- Author(s)
  Sasaki Norihiko、Shinji Seiichi、Shichi Yuuki、Ishiwata Toshiyuki、Arai Tomio、Yamada Takeshi、Takahashi Goro、Ohta Ryo、Sonoda Hiromichi、Matsuda Akihisa、Iwai Takuma、Takeda Kohki、Yonaga Kazuhide、Ueda Koji、Kuriyama Sho、Miyasaka Toshimitsu、Yoshida Hiroshi
- Journal Title
  
  Biochemistry and Biophysics Reports
  
  Volume: 30 Pages: 101239-101239
- DOI
  10.1016/j.bbrep.2022.101239
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K09207, KAKENHI-PROJECT-19K11759
[Journal Article] A New Anorectal Melanoma Cell Line Derived from a Primary Human Rectal Tumor2022
- Author(s)
  Shinji Seiichi、Shichi Yuuki、Yamada Takeshi、Takahashi Goro、Ohta Ryo、Sonoda Hiromichi、Matsuda Akihisa、Yonaga Kazuhide、Iwai Takuma、Takeda Kohki、Ueda Koji、Kuriyama Sho、Miyasaka Toshimitsu、Ueda Yoshibumi、Sasaki Norihiko、Takahashi Kimimasa、Ohashi Ryuji、Ishiwata Toshiyuki、Arai Tomio、Yoshida Hiroshi
- Journal Title
  
  Journal of Nippon Medical School
  
  Volume: 89 Issue: 4 Pages: 368-376
- DOI
  10.1272/jnms.JNMS.2022_89-402
- NAID
  130008144205
- ISSN
  1345-4676, 1347-3409
- Year and Date
  2022-08-25
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K07685, KAKENHI-PROJECT-19K09207, KAKENHI-PROJECT-19K11759
[Journal Article] Polyvinyl alcohol increased growth, migration, invasion, and sphere size in the PK-8 pancreatic ductal adenocarcinoma cell line2021
- Author(s)
  Fujiya Gomi, Norihiko Sasaki, Yuuki Shichi, Fuuka Minami, Seiichi Shinji, Masashi Toyoda, Toshiyuki Ishiwata
- Journal Title
  
  Heliyon
  
  Volume: 7 Issue: 2 Pages: e06182-e06182
- DOI
  10.1016/j.heliyon.2021.e06182
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K09207, KAKENHI-PROJECT-19K11759, KAKENHI-PROJECT-21K08764
[Journal Article] Glycan characteristics of human heart constituent cells maintaining organ function: relatively stable glycan profiles in cellular senescence2021
- Author(s)
  Itakura Yoko、Sasaki Norihiko、Toyoda Masashi
- Journal Title
  
  Biogerontology
  
  Volume: 22 Issue: 6 Pages: 623-637
- DOI
  10.1007/s10522-021-09940-z
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K11666, KAKENHI-PROJECT-19K11759
[Journal Article] Gangliosides as signaling regulators in cancer2021
- Author(s)
  Sasaki Norihiko , Toyoda Masashi , Ishiwata Toshiyuki
- Journal Title
  
  International Journal of Molecular Sciences
  
  Volume: 22 Issue: 10 Pages: 5076-5076
- DOI
  10.3390/ijms22105076
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K09207, KAKENHI-PROJECT-19K11759
[Journal Article] Cell Surface and Functional Features of Cortical Bone Stem Cells2021
- Author(s)
  Sasaki Norihiko、Itakura Yoko、Mohsin Sadia、Ishigami Tomoaki、Kubo Hajime、Chiba Yumi
- Journal Title
  
  International Journal of Molecular Sciences
  
  Volume: 22 Issue: 21 Pages: 11849-11849
- DOI
  10.3390/ijms222111849
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K11666, KAKENHI-PROJECT-18K19689, KAKENHI-PROJECT-21K19659, KAKENHI-PROJECT-19K11759
[Journal Article] Morphofunctional analysis of human pancreatic cancer cell lines in 2- and 3-dimensional cultures2021
- Author(s)
  Minami Fuuka, Sasaki Norihiko, Shichi Yuuki, Gomi Fujiya, Michishita Masaki, Ohkusu-Tsukada Kozo, Toyoda Masashi, Takahashi Kimimasa, Ishiwata Toshiyuki
- Journal Title
  
  Scientific Reports
  
  Volume: 11 Issue: 1 Pages: 6775-6775
- DOI
  10.1038/s41598-021-86028-1
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K09207, KAKENHI-PROJECT-19K11759, KAKENHI-PROJECT-19H03132, KAKENHI-PROJECT-21K08764
[Journal Article] Rapamycin promotes endothelial?mesenchymal transition during stress-induced premature senescence through the activation of autophagy2020
- Author(s)
  Sasaki Norihiko、Itakura Yoko、Toyoda Masashi
- Journal Title
  
  Cell Communication and Signaling
  
  Volume: 18 Issue: 1 Pages: 43-43
- DOI
  10.1186/s12964-020-00533-w
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K08263, KAKENHI-PROJECT-19K11759
[Journal Article] Characterization of the metastatic potential of the floating cell component of MIA PaCa-2, a human pancreatic cancer cell line2020
- Author(s)
  Sasaki Norihiko、Gomi Fujiya、Hasegawa Fumio、Hirano Kazumi、Fujiwara Masakazu、Toyoda Masashi、Ishiwata Toshiyuki
- Journal Title
  
  Biochemical and Biophysical Research Communications
  
  Volume: 522 Issue: 4 Pages: 881-888
- DOI
  10.1016/j.bbrc.2019.11.120
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K09207, KAKENHI-PROJECT-16K08263, KAKENHI-PROJECT-19K11759
[Journal Article] FGFR4 Inhibitor BLU9931 Attenuates Pancreatic Cancer Cell Proliferation and Invasion While Inducing Senescence: Evidence for Senolytic Therapy Potential in Pancreatic Cancer2020
- Author(s)
  Sasaki N, Gomi F, Yoshimura H, Yamamoto M, Matsuda Y, Michishita M, Hatakeyama H, Kawano Y, Toyoda M, Korc M, Ishiwata T.
- Journal Title
  
  Cancers (Basel)
  
  Volume: 12 Issue: 10 Pages: 2976-2976
- DOI
  10.3390/cancers12102976
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K06391, KAKENHI-PROJECT-19K06408, KAKENHI-PROJECT-19K09207, KAKENHI-PROJECT-19K11759
[Journal Article] Comparison of functional glycans between cancer stem cells and normal stem cells.2019
- Author(s)
  Sasaki Norihiko, Itakura Yoko, Gomi Fujiya, Hirano Kazumi, Toyoda Masashi, Ishiwata Toshiyuki.
- Journal Title
  
  Histology & Histopathology
  
  Volume: 34 Pages: 995-1007
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K11759
[Journal Article] Vascular Diseases and Gangliosides2019
- Author(s)
  Sasaki Norihiko、Toyoda Masashi
- Journal Title
  
  International Journal of Molecular Sciences
  
  Volume: 20 Issue: 24 Pages: 6362-6362
- DOI
  10.3390/ijms20246362
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K08263, KAKENHI-PROJECT-19K11759
[Journal Article] Ganglioside GM2, highly expressed in the MIA PaCa-2 pancreatic ductal adenocarcinoma cell line, is correlated with growth, invasion, and advanced stage2019
- Author(s)
  Sasaki Norihiko、Hirabayashi Kenichi、Michishita Masaki、Takahashi Kimimasa、Hasegawa Fumio、Gomi Fujiya、Itakura Yoko、Nakamura Naoya、Toyoda Masashi、Ishiwata Toshiyuki
- Journal Title
  
  Scientific Reports
  
  Volume: 9 Issue: 1 Pages: 19369-19369
- DOI
  10.1038/s41598-019-55867-4
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K06391, KAKENHI-PROJECT-19K09207, KAKENHI-PROJECT-16K08263, KAKENHI-PROJECT-19K11759
[Journal Article] Comparison of functional glycans between cancer stem cells and normal stem cells2019
- Author(s)
  Sasaki Norihiko, Itakura Yoko, Gomi Fujiya, Hirano Kazumi, Toyoda Masashi, Ishiwata Toshiyuki
- Journal Title
  
  Histology & Histopathology
  
  Volume: 34 Pages: 995-1007
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K08263
[Journal Article] Fetal bovine serum enlarges the size of human pancreatic cancer spheres accompanied by an increase in the expression of cancer stem cell markers2019
- Author(s)
  Sasaki Norihiko、Toyoda Masashi、Hasegawa Fumio、Fujiwara Masakazu、Gomi Fujiya、Ishiwata Toshiyuki
- Journal Title
  
  Biochemical and Biophysical Research Communications
  
  Volume: 514 Issue: 1 Pages: 112-117
- DOI
  10.1016/j.bbrc.2019.04.117
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K08263, KAKENHI-PROJECT-19K11759
[Journal Article] Gangliosides Contribute to Vascular Insulin Resistance2019
- Author(s)
  Sasaki Norihiko、Itakura Yoko、Toyoda Masashi
- Journal Title
  
  International Journal of Molecular Sciences
  
  Volume: 20 Issue: 8 Pages: 1819-1819
- DOI
  10.3390/ijms20081819
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K08263, KAKENHI-PROJECT-16K19098, KAKENHI-PROJECT-19K11759
[Journal Article] Enhanced morphological and functional differences of pancreatic cancer with epithelial or mesenchymal characteristics in 3D culture.2019
- Author(s)
  Shichi Y, Sasaki N, Michishita M, Hasegawa F, Matsuda Y, Arai T, Gomi F, Aida J, Takubo K, Toyoda M, Yoshimura H, Takahashi K, Ishiwata T.
- Journal Title
  
  Scientific Reports
  
  Volume: 9 Issue: 1 Pages: 10871-10871
- DOI
  10.1038/s41598-019-47416-w
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K06391, KAKENHI-PROJECT-16K08263, KAKENHI-PROJECT-19K11759
[Journal Article] Establishment and characterization of a novel neuroendocrine carcinoma cell line derived from a human ascending colon tumor.2019
- Author(s)
  Shinji S, Sasaki N, Yamada T, Koizumi M, Matsuda A, Ohta R, Yokoyama Y, Takahashi G, Hotta M, Hara K, Takeda K, Ueda K, Kuriyama S, Ishiwata T, Murakami T, Ueda Y, Kanazawa Y, Yoshida H.
- Journal Title
  
  Cancer Sci.
  
  Volume: 110(12) Issue: 12 Pages: 3708-3717
- DOI
  10.1111/cas.14221
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K08276, KAKENHI-PROJECT-19K07685, KAKENHI-PROJECT-19K09160, KAKENHI-PROJECT-16K08263, KAKENHI-PROJECT-17K19341, KAKENHI-PROJECT-19K11759
[Journal Article] Reduced expression of the H19 long non-coding RNA inhibits pancreatic cancer metastasis2018
- Author(s)
  Yoshimura Hisashi、Matsuda Yoko、Yamamoto Masami、Michishita Masaki、Takahashi Kimimasa、Sasaki Norihiko、Ishikawa Naoshi、Aida Junko、Takubo Kaiyo、Arai Tomio、Ishiwata Toshiyuki
- Journal Title
  
  Laboratory Investigation
  
  Volume: 印刷中 Issue: 6 Pages: 814-824
- DOI
  10.1038/s41374-018-0048-1
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K08263, KAKENHI-PROJECT-16K10613
[Journal Article] Pancreatic cancer stem cells: features and detection methods2018
- Author(s)
  Ishiwata Toshiyuki、Matsuda Yoko、Yoshimura Hisashi、Sasaki Norihiko、Ishiwata Shunji、Ishikawa Naoshi、Takubo Kaiyo、Arai Tomio、Aida Junko
- Journal Title
  
  Pathology & Oncology Research
  
  Volume: 24 Issue: 4 Pages: 797-805
- DOI
  10.1007/s12253-018-0420-x
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K08263, KAKENHI-PROJECT-16K10613
[Journal Article] <i>H19</i> long non-coding RNA contributes to sphere formation and invasion through regulation of CD24 and integrin expression in pancreatic cancer cells2018
- Author(s)
  Sasaki Norihiko、Toyoda Masashi、Yoshimura Hisashi、Matsuda Yoko、Arai Tomio、Takubo Kaiyo、Aida Junko、Ishiwata Toshiyuki
- Journal Title
  
  Oncotarget
  
  Volume: 9 Issue: 78 Pages: 34719-34734
- DOI
  10.18632/oncotarget.26176
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K08263, KAKENHI-PROJECT-18K14597, KAKENHI-PROJECT-16K10613
[Journal Article] Qualitative and quantitative alterations in intracellular and membrane glycoproteins maintain the balance between cellular senescence and human aging2018
- Author(s)
  Itakura Yoko、Sasaki Norihiko、Toyoda Masashi
- Journal Title
  
  Aging
  
  Volume: 10 Issue: 8 Pages: 2190-2208
- DOI
  10.18632/aging.101540
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K08263, KAKENHI-PROJECT-16K19098
[Journal Article] Stemness and anti-cancer drug resistance in ATP-binding cassette subfamily G member 2 highly expressed pancreatic cancer is induced in 3D culture conditions2018
- Author(s)
  Sasaki Norihiko、Ishiwata Toshiyuki、Hasegawa Fumio、Michishita Masaki、Kawai Hiroki、Matsuda Yoko、Arai Tomio、Ishikawa Naoshi、Aida Junko、Takubo Kaiyo、Toyoda Masashi
- Journal Title
  
  Cancer Science
  
  Volume: 109 Issue: 4 Pages: 1135-1146
- DOI
  10.1111/cas.13533
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K08263, KAKENHI-PROJECT-16K10613
[Journal Article] Ganglioside GM1 contributes to extracellular/intracellular regulation of insulin resistance, impairment of insulin signaling and down-stream eNOS activation, in human aortic endothelial cells after short- or long-term exposure to TNFα2017
- Author(s)
  Sasaki Norihiko、Itakura Yoko、Toyoda Masashi
- Journal Title
  
  Oncotarget
  
  Volume: 9 Issue: 5 Pages: 5562-5577
- DOI
  10.18632/oncotarget.23726
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K08263
[Journal Article] Sialylation regulates myofibroblast differentiation of human skin fibroblasts.2017
- Author(s)
  Sasaki N, Itakura Y, Toyoda M
- Journal Title
  
  Stem Cell Research & Therapy
  
  Volume: 8(1) Issue: 1 Pages: 81-81
- DOI
  10.1186/s13287-017-0534-1
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-16K08263
[Journal Article] Electron microscopic analysis of different cell types in human pancreatic cancer spheres2017
- Author(s)
  Ishiwata Toshiyuki、Hasegawa Fumio、Michishita Masaki、Sasaki Norihiko、Ishikawa Naoshi、Takubo Kaiyo、Matsuda Yoko、Arai Tomio、Aida Junko
- Journal Title
  
  Oncology Letters
  
  Volume: 15 Pages: 2485-2490
- DOI
  10.3892/ol.2017.7554
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K08263, KAKENHI-PROJECT-16K10613
[Journal Article] N- and O-glycan cell surface protein modifications associated with cellular senescence and human aging.2016
- Author(s)
  Itakura Y, Sasaki N, Kami D, Gojo S, Umezawa A, Toyoda M
- Journal Title
  
  Cell Biosci.
  
  Volume: 6(14) Issue: 1 Pages: 14-14
- DOI
  10.1186/s13578-016-0079-5
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-26671017, KAKENHI-PROJECT-25670182
[Journal Article] Ganglioside GM1 contributes to the state of insulin resistance in senescent human arterial endothelial cells.2015
- Author(s)
  Sasaki N, Itakura Y, Toyoda M.
- Journal Title
  
  J. Biol. Chem.
  
  Volume: 290 Issue: 42 Pages: 25475-25486
- DOI
  10.1074/jbc.m115.684274
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-26671017, KAKENHI-PROJECT-25670182
[Journal Article] Glycoconjugates and related molecules in human vascular endothelial cells2013
- Author(s)
  Sasaki N and Toyoda M
- Journal Title
  
  Int. J. Vasc. Med
  
  Volume: VOL2013 Pages: 1-10
- DOI
  10.1155/2013/963596
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24890298
[Patent] 医薬組成物2021
- Inventor(s)
  佐々木紀彦、石渡俊行
- Industrial Property Rights Holder
  佐々木紀彦、石渡俊行
- Industrial Property Rights Type
  特許
- Industrial Property Number
  2021-003557
- Filing Date
  2021
- Data Source
  KAKENHI-PROJECT-19K11759
[Patent] 膵臓がんの診断補助方法及び膵臓がん治療用医薬組成物2020
- Inventor(s)
  佐々木紀彦、石渡俊行
- Industrial Property Rights Holder
  佐々木紀彦、石渡俊行
- Industrial Property Rights Type
  特許
- Industrial Property Number
  2020-032798
- Filing Date
  2020
- Data Source
  KAKENHI-PROJECT-16K08263
[Patent] 膵臓がんの診断補助方法及び膵臓がん治療用医薬組成物2020
- Inventor(s)
  佐々木紀彦、石渡俊行
- Industrial Property Rights Holder
  佐々木紀彦、石渡俊行
- Industrial Property Rights Type
  特許
- Industrial Property Number
  2020-032798
- Filing Date
  2020
- Data Source
  KAKENHI-PROJECT-19K11759
[Presentation] 肝転移性の異なる大腸がん細胞株におけるホスファチジルコリンおよびホスファチジルエタノールアミン含有量の比較2024
- Author(s)
  佐々木洋子、林康広、吉川慶美、吉田裕香子、石本奈保、田中万結、佐々木紀彦、松本直樹、岡沙織、入村達郎、山下純
- Organizer
  日本薬学会第144年会
- Data Source
  KAKENHI-PROJECT-20K09066
[Presentation] 細胞内型ホスホリパーゼA1のリン酸化・脱リン酸化酵素とその標的部位の同定2024
- Author(s)
  松本直樹、原恭平、佐竹勝行、鈴木亜深、矢崎智大、佐々木洋子、山下純
- Organizer
  日本薬学会第144年会
- Data Source
  KAKENHI-PROJECT-20K09066
[Presentation] 細胞内型ホスホリパーゼA1 DDHD1はリン酸化により接着点（Focal adhesion）へ局在する2023
- Author(s)
  松本直樹、結城桜、菅野愛奈、森田祐基、山本滉大、佐々木洋子、岡沙織、荒井斉祐、和田郁夫、山下純
- Organizer
  日本脂質生化学会
- Data Source
  KAKENHI-PROJECT-20K09066
[Presentation] Spatiotemporal changes of cardiac glycans in aging2023
- Author(s)
  Itakura Y, Sasaki N, Toyoda M
- Organizer
  IAGG-AOR 2023
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K11794
[Presentation] ホスホリパーゼA1 DDHD1のアフィニティプローブによる検出とリン酸化による細胞内局在の解析2023
- Author(s)
  結城桜、菅野愛奈、森田祐基、山本滉大、松本直樹、佐々木洋子、岡沙織、荒井斉祐、和田郁夫、山下純
- Organizer
  第96回日本生化学会大会
- Data Source
  KAKENHI-PROJECT-20K09066
[Presentation] 細胞内型ホスホリパーゼA1の酵素活性に対する二価金属イオンの反応性の相違と相互作用の解析2023
- Author(s)
  松本直樹、除川杏実、浦山和香子、佐々木洋子、山下純
- Organizer
  日本薬学会第143年会
- Data Source
  KAKENHI-PROJECT-20K09066
[Presentation] 加齢に伴う心臓の組織変化と糖鎖の役割2023
- Author(s)
  板倉陽子、佐々木紀彦、大瀬賢介、吉田友里香、豊田雅士
- Organizer
  第46回日本基礎老化学会
- Data Source
  KAKENHI-PROJECT-22K11794
[Presentation] マウス大腸がん細胞株と肝高転移性の亜株におけるホスファチジルコリンおよびホスファチジルエタノールアミン含有量の比較2023
- Author(s)
  佐々木洋子、林康広、佐々木紀彦、松本直樹、岡沙織、入村達郎、山下純
- Organizer
  第82回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-20K09066
[Presentation] ポリコーム抑制複合体2の働きで増加するガングリオシドが脱分化型平滑筋細胞の増殖と遊走に関与する2023
- Author(s)
  佐々木紀彦、平野和巳、志智優樹、板倉陽子、石渡俊行、豊田雅士
- Organizer
  CVMW2023
- Data Source
  KAKENHI-PROJECT-22K11794
[Presentation] 細胞内型ホスホリパーゼA1の酵素活性に対する鉄及び亜鉛の阻害機構の解析2023
- Author(s)
  松本直樹、浦山和香子、除川杏実、佐々木洋子、山下純
- Organizer
  第46回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-20K09066
[Presentation] FGFR4 inhibitors reduced cell proliferation and migration, and induced cellular senescence in pancreatic cancer cells2023
- Author(s)
  Ishiwata T, Sasaki N, Gomi F, Shichi Y, Shinji S, Nonaka K, Toyoda M
- Organizer
  IAGG-AOR 2023
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K11794
[Presentation] 加齢に伴うマウス心臓組織変化と領域特異的な糖鎖変化の意義2023
- Author(s)
  板倉陽子、佐々木紀彦、吉田友里香、豊田雅士
- Organizer
  第42回日本糖質学会
- Data Source
  KAKENHI-PROJECT-22K11794
[Presentation] 心臓移植患者への看護支援の効果指標に関する検討2023
- Author(s)
  千葉由美、豊田吉哉、佐々木康之輔、小野稔
- Organizer
  第59回日本移植学会総会
- Data Source
  KAKENHI-PROJECT-21K19659
[Presentation] Comparison of phosphatidylcholine and phosphatidylethanolamine contents in mouse colon cancer metastatic variant cells2023
- Author(s)
  Sasaki Y, Hayashi Y, Gomi F, Sasaki N, Matsumoto N, Oka S, Irimura T, Yamashita J
- Organizer
  第82回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-22K11794
[Presentation] Increased gangliosides via polycomb repressor complex 2 contribute to the proliferation and migration of dedifferentiated vascular smooth muscle cells2023
- Author(s)
  Sasaki N, Hirano K, Shichi Y, Itakura Y, Ishiwata T, Toyoda M
- Organizer
  IAGG-AOR 2023
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K11794
[Presentation] ホスホリパーゼA1 DDHD1のアフィニティプローブによる検出とリン酸化による細胞内局在の解析2023
- Author(s)
  結城桜、菅野愛奈、森田祐基、山本滉大、松本直樹、佐々木洋子、岡沙織、荒井斉祐、和田郁夫、山下純
- Organizer
  第23回 Pharmaco-Hematology (PH)シンポジウム
- Data Source
  KAKENHI-PROJECT-20K09066
[Presentation] 加齢心臓における部位特異的な糖鎖変化が示す組織変化と糖鎖の意義2023
- Author(s)
  板倉陽子、佐々木紀彦、吉田友里香、豊田雅士
- Organizer
  第96回日本生化学会大会
- Data Source
  KAKENHI-PROJECT-22K11794
[Presentation] FGFR4 inhibitors reduced cell proliferation and migration, and induced cellular senescence in pancreatic cancer.2023
- Author(s)
  Toshiyuki Ishiwata, Norihiko Sasaki, Fujiya Gomi, Yuuki Shichi, Seiichi Shinji, Masashi Toyoda.
- Organizer
  AGG Asia/Oceania Regional Congress 2023
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K08764
[Presentation] 膵がん培養細胞株の老化誘導と老化細胞除去療法2022
- Author(s)
  五味不二也, 佐々木紀彦, 志智優樹, 野中敬介, 石渡俊行
- Organizer
  TOBIRA第10回研究交流フォーラム
- Data Source
  KAKENHI-PROJECT-21K08744
[Presentation] 細胞内型ホスホリパーゼA1 のリン酸化と細胞内局在の変化2022
- Author(s)
  松本直樹、佐々木洋子、岡沙織、荒井斉祐、和田郁夫、山下純
- Organizer
  第64回日本脂質生化学会
- Data Source
  KAKENHI-PROJECT-20K09066
[Presentation] Gp130/STAT3シグナル伝達は、長鎖ノンコーディングRNAのH19の発現を含む膵臓癌幹細胞の機能を調節する2022
- Author(s)
  佐々木紀彦, 平野和己, 志智優樹, 五味不二也, 吉村久志, 松下晃, 板倉陽子, 豊田雅士, 石渡俊行
- Organizer
  第81回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-21K08744
[Presentation] 膵がんの上皮間葉系性質と糖鎖発現の多様性2022
- Author(s)
  志智優樹, 佐々木紀彦, 五味不二也, 野中敬介, 石渡俊行
- Organizer
  TOBIRA第10回研究交流フォーラム
- Data Source
  KAKENHI-PROJECT-21K08744
[Presentation] ヒト細胞内型ホスホリパーゼA1のリン酸化は細胞内局在の制御に関わる2022
- Author(s)
  松本直樹、佐々木洋子、岡沙織、荒井斉祐、和田郁夫、山下純
- Organizer
  第95回日本生化学会大会
- Data Source
  KAKENHI-PROJECT-20K09066
[Presentation] ヒト細胞内型ホスホリパーゼA1のリン酸化が細胞内局在に与える影響2022
- Author(s)
  松本直樹、佐々木洋子、岡沙織、荒井斉祐、和田郁夫、山下純
- Organizer
  日本薬学会第142年会
- Data Source
  KAKENHI-PROJECT-20K09066
[Presentation] 3次元培養による膵癌培養細胞の上皮間葉系形質と粘液産生能の比較検討2022
- Author(s)
  志智優樹, 長谷川康子, 佐々木紀彦, 五味不二也, 野中敬介, 吉村久志, 高橋公正, 豊田雅士, 新井冨生, 石渡俊行
- Organizer
  第111回日本病理学会総会
- Data Source
  KAKENHI-PROJECT-21K08744
[Presentation] 3次元培養による膵癌細胞株の上皮間葉系形質の増強2022
- Author(s)
  石渡俊行, 志智優樹, 五味不二也, 野中敬介, 佐々木紀彦, 豊田雅士, 高橋公正, 新井冨生
- Organizer
  第81回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-21K08744
[Presentation] FGFR4阻害剤BLU554の膵癌細胞株に対する効果2022
- Author(s)
  五味不二也, 佐々木紀彦, 志智優樹, 野中敬介, 豊田雅士, 石渡俊行
- Organizer
  第81回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-21K08744
[Presentation] 大腸がん細胞株の親株と肝高転移性の亜株におけるリゾホスファチジルコリンアシルトランスフェラーゼ (LPCAT) 発現量の比較2022
- Author(s)
  佐々木洋子、林康広、佐々木紀彦、松本直樹、岡沙織、入村達郎、山下純
- Organizer
  第45回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-20K09066
[Presentation] TGF-beta1 induces epithelial-mesenchymal transition in the human colorectal neuroendocrine carcinoma cell line SS-22021
- Author(s)
  Seiichi Shinji, Norihiko Sasaki, Takeshi Yamada, Akihisa Matsuda, Ryo Ohta, Hiromichi Sonoda, Kazuhide Yonaga, Goro Takahashi, Takuma Iwai, Kohki Takeda, Koji Ueda, Sho Kuriyama, Toshimitsu Miyasaka, Fujiya Gomi, Toshiyuki Ishiwata, Hiroshi Yoshida
- Organizer
  第80回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-19K11759
[Presentation] 2次元培養と3次元培養による膵癌培養細胞株の形態・機能変化と薬剤感受性の検討2021
- Author(s)
  石渡俊行, 南風花, 佐々木紀彦, 志智優樹, 五味不二也, 道下正貴, 豊田雅士
- Organizer
  第110回日本病理学会総会
- Data Source
  KAKENHI-PROJECT-21K08744
[Presentation] 2次元培養と3次元培養による膵癌培養細胞株の形態・機能変化と薬剤感受性の検討2021
- Author(s)
  石渡俊行, 南風花, 佐々木紀彦, 志智優樹, 五味不二也, 道下正貴, 豊田雅士
- Organizer
  第111回日本病理学会総会
- Data Source
  KAKENHI-PROJECT-19K11759
[Presentation] FGFR4 inhibitor BLU9931 additively induces cellular senescence in pancreatic cancer cell for senolytic therapy2021
- Author(s)
  Norihiko Sasaki, Fujiya Gomi, Hisashi Yoshimura, Masami Yamamoto, Yoko Matsuda, Masaki Michishita, Hitoshi Hatakeyama, Yoichi Kawano, Yoko Itakura, Masashi Toyoda, Murray Korc, Toshiyuki Ishiwata
- Organizer
  The American Association for Cancer Research Annual Meeting 2021
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K11759
[Presentation] 3次元培養による膵癌培養細胞株の形態および機能的特徴と薬剤感受性の検討2021
- Author(s)
  志智優樹, 南風花, 佐々木紀彦, 五味不二也, 道下正貴, 塚田晃三, 豊田雅士, 高橋公正, 石渡俊行
- Organizer
  第80回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-21K08744
[Presentation] 新規消化管神経内分泌腫瘍細胞株の性状解析2021
- Author(s)
  進士誠一、山田岳史、松田明久、太田竜、園田寛道、高橋吾郎、岩井拓磨、武田幸樹、上田康二、栗山翔、宮坂俊光、佐々木紀彦、石渡俊行、吉田寛
- Organizer
  第121回日本外科学会定期学術集会
- Data Source
  KAKENHI-PROJECT-19K11759
[Presentation] Polyvinyl alcoholは膵癌細胞の遊走、浸潤、sphere形成能を増加させる2021
- Author(s)
  五味不二也, 佐々木紀彦, 志智優樹, 南風花, 進士誠一, 豊田雅士, 石渡俊行
- Organizer
  第111回日本病理学会総会
- Data Source
  KAKENHI-PROJECT-19K11759
[Presentation] Cellular senescence is additively induced in pancreatic cancer cell by FGFR4 inhibitor BLU99312021
- Author(s)
  Norihiko Sasaki, Fujiya Gomi, Hisashi Yoshimura, Masami Yamamoto, Yoko Matsuda, Masaki Michishita, Hitoshi Hatakeyama, Yoichi Kawano, Yoko Itakura, Masashi Toyoda, Murray Korc, Toshiyuki Ishiwata
- Organizer
  第80回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-19K11759
[Presentation] レクチンマイクロアレイ法を用いたマウス心臓の加齢に伴う糖鎖変化と局在に関する比較解析2021
- Author(s)
  板倉陽子、佐々木紀彦、豊田雅士
- Organizer
  第94回日本生化学会大会
- Data Source
  KAKENHI-PROJECT-19K11759
[Presentation] Morphofunctional features and drug sensitivities of pancreatic ductal adenocarcinoma cells in three-dimensional cultures2021
- Author(s)
  Yuuki Shichi, Fuuka Minami, Norihiko Sasaki, Fujiya Gomi, Masaki Michishita, Kozo Ohkusu-Tsukada, Masashi Toyoda, Kimimasa Takahashi, Toshiyuki Ishiwata
- Organizer
  第80回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-19K11759
[Presentation] 心臓構成細胞における細胞老化と糖鎖特異性に関する基礎的解析2021
- Author(s)
  板倉陽子、佐々木紀彦、豊田雅士
- Organizer
  CVMW2021「第29回日本血管生物医学会学術集会（JVBMO）
- Data Source
  KAKENHI-PROJECT-19K11759
[Presentation] FGFR4シグナル抑制による膵癌の老化誘導と、老化細胞死誘導薬の有効性2021
- Author(s)
  佐々木紀彦, 五味不二也, 吉村久志, 山本昌美, 松田陽子, 道下正貴, 畠山仁, 川野陽一, 板倉陽子, 豊田雅士, マレーコーク, 石渡俊行
- Organizer
  第52回日本膵臓学会大会
- Data Source
  KAKENHI-PROJECT-19K11759
[Presentation] 細胞外スルファターゼ-活性を検出する蛍光プローブの開発2021
- Author(s)
  アファメドカシフィア、小和田俊行、佐々木紀彦、水上進
- Organizer
  第141回日本薬学会
- Data Source
  KAKENHI-PROJECT-19K11759
[Presentation] Effects of polyvinyl alcohol on the pancreatic ductal adenocarcinoma cell lines in 2D and 3D cultures2021
- Author(s)
  Fujiya Gomi, Norihiko Sasaki, Yuuki Shichi Seiichi Shinji, Fumio Hasegawa, Kimimasa Takahashi, Masashi Toyoda, Toshiyuki Ishiwata
- Organizer
  第80回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-19K11759
[Presentation] ヒト血管平滑筋細胞の形質転換とガングリオシド2021
- Author(s)
  佐々木紀彦、平野和巳、志智優樹、板倉陽子、石渡俊行、豊田雅士
- Organizer
  CVMW2021「第29回日本血管生物医学会学術集会（JVBMO）
- Data Source
  KAKENHI-PROJECT-19K11759
[Presentation] 細胞老化に伴うヒト心臓構成細胞における糖鎖変化の解析2020
- Author(s)
  板倉陽子、佐々木紀彦、豊田雅士
- Organizer
  第39回日本糖質学会年会
- Data Source
  KAKENHI-PROJECT-19K11759
[Presentation] Morphofunctional analysis of a novel neuroendocrine carcinoma cell line, SS-2 derived from a human ascending colon tumor2020
- Author(s)
  Seiichi Shinji, Norihiko Sasaki, Takeshi Yamada, Akihisa Matsuda, Ryo Ohta, Hiromichi Sonoda, Goro Takahashi, Takuma Iwai, Kohki Takeda, Koji Ueda, Sho Kuriyama, Toshimitsu Miyasaka, Fujiya Gomi, Toshiyuki Ishiwata, Hiroshi Yoshida
- Organizer
  第79回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-19K11759
[Presentation] A newly established neuroendocrine carcinoma cell line from a human ascending colon tumor shows high proliferation and CD133 expression in spherical cancer stem cell-like formation2020
- Author(s)
  Seiichi Shinji, Norihiko Sasaki, Takeshi Yamada, Michihiro Koizumi, Ryo Ohta, Akihisa Matsuda, Goro Takahashi, Masahiro Hotta, Takuma Iwai, Keisuke Hara, Kohki Takeda, Koji Ueda, Sho Kuriyama, Toshiyuki Ishiwata, Hiroshi Yoshida
- Organizer
  The American Association for Cancer Research Annual Meeting 2020
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K11759
[Presentation] The expression and characterization of ganglioside GM2 in pancreatic cancer2020
- Author(s)
  Norihiko Sasaki, Kenichi Hirabayashi, Masaki Michishita, Kimimasa Takahashi, Fumio Hasegawa, Fujiya Gomi, Yoko Itakura, Naoya Nakamura, Masashi Toyoda, Toshiyuki Ishiwata
- Organizer
  第79回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-19K11759
[Presentation] 2次元培養と3次元培養における膵癌培養細胞株の形態、機能解析2020
- Author(s)
  南風花、道下正貴、五味不二也、佐々木紀彦、石渡俊行、塚田晃三
- Organizer
  第109回日本病理学会総会
- Data Source
  KAKENHI-PROJECT-19K11759
[Presentation] Polyvinyl alcohol increases growth, migration, invasion, and sphere formation of pancreatic cancer cells2020
- Author(s)
  Fujiya Gomi, Norihiko Sasaki, Yuuki Shichi, Seiichi Shinji, Fumio Hasegawa, Kimimasa Takahashi, Toshiyuki Ishiwata
- Organizer
  第79回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-19K11759
[Presentation] ガングリオシドGM2陽性膵癌細胞の特性2020
- Author(s)
  佐々木紀彦、平林健一、道下正貴、高橋公正、長谷川文雄、五味不二也、板倉陽子、中村直哉、豊田雅士、石渡俊行
- Organizer
  第39回日本糖質学会年会
- Data Source
  KAKENHI-PROJECT-19K11759
[Presentation] Characteristics of c-kit on Cortical Bone Stem Cells in Vitro2020
- Author(s)
  Yumi Chiba, Norihiko Sasaki, Takuya Seko, Tomoaki Ishigami, Hajime Kubo
- Organizer
  第19回日本再生医療学会総会
- Data Source
  KAKENHI-PROJECT-19K11759
[Presentation] 大腸内分泌細胞癌における癌幹細胞関連遺伝子の同定と解析2020
- Author(s)
  進士誠一、山田岳史、小泉岐博、松田明久、太田竜、横山康行、高橋吾郎、堀田正啓、原敬介、武田幸樹、上田康二、栗山翔、佐々木紀彦、石渡俊行、吉田寛
- Organizer
  第120回日本外科学会定期学術集会
- Data Source
  KAKENHI-PROJECT-19K11759
[Presentation] Increased expression of ganglioside GM2 correlates with aggressiveness of human pancreatic ductal adenocarcinoma2020
- Author(s)
  Norihiko Sasaki, Kenichi Hirabayashi, Masaki Michishita, Kimimasa Takahashi, Fumio Hasegawa, Fujiya Gomi4, Yoko Itakura, Naoya Nakamura, Masashi Toyoda, Toshiyuki Ishiwata
- Organizer
  The American Association for Cancer Research Annual Meeting 2020
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K11759
[Presentation] 膵癌培養細胞の形態的可変性と浮遊細胞の特徴解析2020
- Author(s)
  石渡俊行、佐々木紀彦、長谷川文雄、豊田雅士、五味不二也
- Organizer
  第109回日本病理学会総会
- Data Source
  KAKENHI-PROJECT-19K11759
[Presentation] Alteration of glycans localization with cellular senescence and human aging2019
- Author(s)
  Yoko Itakura, Norihiko Sasaki, Masashi Toyoda
- Organizer
  International Glycoconjugate Organization (Glyco25)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K08263
[Presentation] ヒト冠状動脈内皮細胞の老化に対するラパマイシンの効果について2019
- Author(s)
  佐々木紀彦、板倉陽子、豊田雅士
- Organizer
  第27回日本血管生物医学会学術集会
- Data Source
  KAKENHI-PROJECT-16K08263
[Presentation] H19 long non-coding RNA contributes to the metastasis of pancreatic cancer cells by regulating cell adhesion2019
- Author(s)
  Norihiko Sasaki, Masashi Toyoda, Hisashi Yoshimura, Yoko Matsuda, Tomio Arai, Yoko Itakura, Fujiya Gomi, Junko Aida, Toshiyuki Ishiwata
- Organizer
  第78回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-16K08263
[Presentation] ３次元培養による膵癌培養細胞の上皮間葉系形態と機能解析2019
- Author(s)
  石渡俊行、志知優樹、佐々木紀彦、道下正貴、長谷川文夫、松田陽子、新井富生、五味不二也、相田順子、田久保海誉、豊田雅士、吉村久志、高橋公正
- Organizer
  第50回日本膵臓学会大会
- Data Source
  KAKENHI-PROJECT-16K08263
[Presentation] 膵癌細胞の多様性と可変性の検討2019
- Author(s)
  石渡俊行、佐々木紀彦、五味不二也、長谷川文雄、新井冨生
- Organizer
  第5回がんゲノム・エピゲノム研究会
- Data Source
  KAKENHI-PROJECT-16K08263
[Presentation] Characterization of floating round cells in MIA PaCa-2, human pancreatic cancer cell line2019
- Author(s)
  Fujiya Gomi, Norihiko Sasaki, Kaiyo Takubo, Junko Aida, Tomio Arai, Toshiyuki Ishiwata
- Organizer
  第78回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-19K11759
[Presentation] ３次元培養による膵癌培養細胞の上皮間葉系形態と機能解析2019
- Author(s)
  石渡俊行、志知優樹、佐々木紀彦、道下正貴、長谷川文夫、松田陽子、新井富生、五味不二也、相田順子、田久保海誉、豊田雅士、吉村久志、高橋公正
- Organizer
  第50回日本膵臓学会大会
- Data Source
  KAKENHI-PROJECT-19K11759
[Presentation] Heterogeneity of epithelial-mesenchymal features of pancreatic cancer cells under the 3D culture2019
- Author(s)
  Toshiyuki Ishiwata, Yuuki Shichi, Norihiko Sasaki, Masaki Michishita, Fumio Hasegawa, Yoko Matsuda, Kimimasa Takahashi, Kaiyo Takubo, Tomio Arai, Junko Aida
- Organizer
  第108回日本病理学会総会
- Data Source
  KAKENHI-PROJECT-16K08263
[Presentation] 細胞および個体老化に伴う細胞の品質保持に関わる糖鎖変化の解析2019
- Author(s)
  板倉陽子、佐々木紀彦、豊田雅士
- Organizer
  第42回日本基礎老化学会大会
- Data Source
  KAKENHI-PROJECT-16K08263
[Presentation] 3次元培養による膵癌培養細胞の上皮間葉系性質の解析2019
- Author(s)
  石渡俊行、佐々木紀彦、志智優樹、豊田雅士、長谷川文雄、五味不二也
- Organizer
  第3回がん３次元培養研究会
- Data Source
  KAKENHI-PROJECT-16K08263
[Presentation] Fetal bovine serum enlarges the size of pancreatic cancer spheres with an increase of the cancer stem cell markers2019
- Author(s)
  Toshiyuki Ishiwata, Norihiko Sasaki, Masashi Toyoda, Fumio Hasegawa, Fujiya Gomi
- Organizer
  第78回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-19K11759
[Presentation] ヒト冠状動脈内皮細胞の老化に対するラパマイシンの効果について2019
- Author(s)
  佐々木紀彦、板倉陽子、豊田雅士
- Organizer
  第27回日本血管生物医学会学術集会
- Data Source
  KAKENHI-PROJECT-19K11759
[Presentation] Alteration of glycans localization with cellular senescence and human aging2019
- Author(s)
  Yoko Itakura, Norihiko Sasaki, Masashi Toyoda
- Organizer
  International Glycoconjugate Organization (Glyco25)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K11759
[Presentation] Metastasis-promoting role of H19 long non-coding RNA in pancreatic cancer cells2019
- Author(s)
  Norihiko Sasaki, Masashi Toyoda, Hisashi Yoshimura, Yoko Matsuda, Tomio Arai, Yoko Itakura, Fujiya Gomi, Junko Aida, Toshiyuki Ishiwata
- Organizer
  The American Association for Cancer Research Annual Meeting 2019
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K11759
[Presentation] 血管疾患の早期診断および予防に向けた、老化内皮細胞特異的糖鎖の同定2019
- Author(s)
  佐々木紀彦，水上進、板倉陽子、豊田雅士
- Organizer
  第19回東北大学多元物質科学研究所研究発表会
- Data Source
  KAKENHI-PROJECT-16K08263
[Presentation] Metastasis-promoting role of H19 long non-coding RNA in pancreatic cancer cells2019
- Author(s)
  Norihiko Sasaki, Masashi Toyoda, Hisashi Yoshimura, Yoko Matsuda, Tomio Arai, Yoko Itakura, Fujiya Gomi, Junko Aida, Toshiyuki Ishiwata
- Organizer
  The American Association for Cancer Research Annual Meeting 2019
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K08263
[Presentation] H19 long non-coding RNA contributes to the metastasis of pancreatic cancer cells by regulating cell adhesion2019
- Author(s)
  Norihiko Sasaki, Masashi Toyoda, Hisashi Yoshimura, Yoko Matsuda, Tomio Arai, Yoko Itakura, Fujiya Gomi, Junko Aida, Toshiyuki Ishiwata
- Organizer
  第78回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-19K11759
[Presentation] Characterization of floating round cells in MIA PaCa-2, human pancreatic cancer cell line2019
- Author(s)
  Fujiya Gomi, Norihiko Sasaki, Kaiyo Takubo, Junko Aida, Tomio Arai, Toshiyuki Ishiwata
- Organizer
  第78回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-16K08263
[Presentation] Fetal bovine serum enlarges the size of pancreatic cancer spheres with an increase of the cancer stem cell markers2019
- Author(s)
  Toshiyuki Ishiwata, Norihiko Sasaki, Masashi Toyoda, Fumio Hasegawa, Fujiya Gomi
- Organizer
  第78回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-16K08263
[Presentation] 3次元培養による膵癌培養細胞の上皮間葉系性質の解析2019
- Author(s)
  石渡俊行、佐々木紀彦、志智優樹、豊田雅士、長谷川文雄、五味不二也
- Organizer
  第3回がん３次元培養研究会
- Data Source
  KAKENHI-PROJECT-19K11759
[Presentation] 細胞および個体老化に伴う細胞の品質保持に関わる糖鎖変化の解析2019
- Author(s)
  板倉陽子、佐々木紀彦、豊田雅士
- Organizer
  第42回日本基礎老化学会大会
- Data Source
  KAKENHI-PROJECT-19K11759
[Presentation] Heterogeneity of epithelial-mesenchymal features of pancreatic cancer cells under the 3D culture2019
- Author(s)
  Toshiyuki Ishiwata, Yuuki Shichi, Norihiko Sasaki, Masaki Michishita, Fumio Hasegawa, Yoko Matsuda, Kimimasa Takahashi, Kaiyo Takubo, Tomio Arai, Junko Aida
- Organizer
  第108回日本病理学会総会
- Data Source
  KAKENHI-PROJECT-19K11759
[Presentation] 膵癌細胞の多様性と可変性の検討2019
- Author(s)
  石渡俊行、佐々木紀彦、五味不二也、長谷川文雄、新井冨生
- Organizer
  第5回がんゲノム・エピゲノム研究会
- Data Source
  KAKENHI-PROJECT-19K11759
[Presentation] 血管疾患の早期診断および予防に向けた、老化内皮細胞特異的糖鎖の同定2019
- Author(s)
  佐々木紀彦，水上進、板倉陽子、豊田雅士
- Organizer
  第19回東北大学多元物質科学研究所研究発表会
- Data Source
  KAKENHI-PROJECT-19K11759
[Presentation] Ganglioside contributes to insulin resistance in senescent and TNFα-stimulated human aortic endothelial cells2018
- Author(s)
  Norihiko Sasaki, Yoko Itakura, Toyoda Masashi
- Organizer
  International Vascular Biology Meeting 2018
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K08263
[Presentation] Pancreatic cancer cells forming spheres differentiate in serum containing culture media2018
- Author(s)
  Toshiyuki Ishiwata, Norihiko Sasaki, Fumio Hasegawa, Masaki Michishita, Fujiya Gomi, Naoshi Ishikawa, Kaiyo Takubo, Yoko Matsuda, Tomio Arai, Junko Aida
- Organizer
  第77回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-16K08263
[Presentation] 長鎖non-coding RNA, H19の膵癌における機能的役割について2018
- Author(s)
  佐々木紀彦，豊田雅士，吉村久志，松田陽子，板倉陽子，五味不二也，相田順子，新井冨生，石渡俊行
- Organizer
  第４回がんゲノム・エピゲノム研究会
- Data Source
  KAKENHI-PROJECT-16K08263
[Presentation] Cardiac tissue glycome mapping using lectin microarray for heart failure cell therapy2018
- Author(s)
  Yoko Itakura, Yurika Kikkawa, Yuina Murakami, Atsushi Kuno, Chiaki Nagai-Okatani, Norihiko Sasaki and Masashi Toyoda
- Organizer
  JAACT2018
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K08263
[Presentation] 1.Ganglioside contributes to insulin resistance in senescent and TNFα-stimulated human aortic endothelial cells.2018
- Author(s)
  Norihiko Sasaki, Yoko Itakira, Masashi Toyoda
- Organizer
  20th International Vacular Biology Meeting
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K08263
[Presentation] ABCG2-positive cells derived from ABCG2-negative pancreatic cancer cells in 3D-culture conditions show high stemness and anti-cancer drug resistance.2018
- Author(s)
  Norihiko Sasaki, Fumio Hasegawa, Masaki Michishita, Yoko Matsuda, Tomio Arai, Naoshi Ishikawa, Yoko Itakura, Junko Aida, Kaiyo Takubo, Masashi Toyoda, Toshiyuki Ishiwata
- Organizer
  The American Association for Cancer Research Annual Meeting 2018
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K08263
[Presentation] ヒト膵癌細胞由来スフェアの形態学的、分子生物学的解析2018
- Author(s)
  石渡俊行、佐々木紀彦、長谷川文雄、道下正貴、石川直、田久保海誉、松田陽子、新井冨生、相田順子
- Organizer
  第107回日本病理学会総会
- Data Source
  KAKENHI-PROJECT-16K08263
[Presentation] 老化血管内皮細胞由来因子の高感度検出技術の開発とその応用2018
- Author(s)
  佐々木紀彦、水上進、板倉陽子、豊田雅士
- Organizer
  第18回東北大学多元物質科学研究所研究発表会
- Data Source
  KAKENHI-PROJECT-16K08263
[Presentation] ABCG2-positive cells derived from ABCG2-negative pancreatic cancer cells in 3D-culture conditions show high stemness and anti-cancer drug resistance2018
- Author(s)
  Norihiko Sasaki, Fumio Hasegawa, Masaki Michishita, Yoko Matsuda, Tomio Arai, Naoshi Ishikawa, Yoko Itakura, Junko Aida, Kaiyo Takubo, Masashi Toyoda, Toshiyuki Ishiwata
- Organizer
  The American Association for Cancer Research Annual Meeting 2018
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K08263
[Presentation] Characteristics of E-cadherin high and low expressed human pancreatic cancer cell lines cultured in 2D and 3D-cultures2018
- Author(s)
  Shichi Yuuki, Norihiko Sasaki, Masaki Michishita, Kiminasa Takahashi, Toshiyuki Ishiwata
- Organizer
  第77回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-16K08263
[Presentation] ABCG2陽性膵癌細胞の高い幹細胞性と薬剤排出能は３次元培養によって誘導される2018
- Author(s)
  石渡俊行、佐々木紀彦、長谷川文夫、道下正貴、石川直、田久保海誉、松田陽子、新井富生、相田順子
- Organizer
  第49回日本膵臓学会大会
- Data Source
  KAKENHI-PROJECT-16K08263
[Presentation] Comparative analysis of glycan alterations in intracellular and membrane glycoproteins with cellular senescence and human aging2018
- Author(s)
  Yoko Itakura, Norihiko Sasaki, Masashi Toyoda
- Organizer
  10th ACGG Conference
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K08263
[Presentation] Ganglioside contributes to regulation of insulin resistance in human aortic endothelial cells after TNFα stimulation.2017
- Author(s)
  Norihiko Sasaki, Yoko Itakura, Masashi Toyoda
- Organizer
  The 12th International Congress on Innovations in Coronary Artery Disease
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K08263
[Presentation] ガングリオシドGM1はTNFαによる血管のインスリン抵抗性に関与する2017
- Author(s)
  佐々木紀彦、板倉　陽子、豊田雅士
- Organizer
  第25回日本血管生物医学会学術集
- Data Source
  KAKENHI-PROJECT-16K08263
[Presentation] The cell surface and intracellular glycan profiling with the cellular senescence and the human aging2017
- Author(s)
  Yoko Itakura, Norihiko Sasaki, Toyoda Masashi
- Organizer
  Keystone Symposia "Aging&Mechanisms of Aging-Related Disease 2017"
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K08263
[Presentation] Comparison of membrane with cytoplasmic glycan profile changing with cellular senescence and human aging2017
- Author(s)
  Yoko Itakura, Norihiko Sasaki, Masashi Toyoda
- Organizer
  24th International symposium on glycoconjugates
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K08263
[Presentation] Sialic acids play functionally important roles in human skin fibroblasts2017
- Author(s)
  Norihiko Sasaki, Yoko Itakura, Toyoda Masashi
- Organizer
  Keystone Symposia "Aging&Mechanisms of Aging-Related Disease 2017"
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K08263
[Presentation] Insulin resistance mediated by ganglioside in TNFa-stimulated human vascular endothelial cells2016
- Author(s)
  佐々木紀彦、板倉　陽子、豊田　雅士
- Organizer
  第24回日本血管生物医学会学術集会
- Place of Presentation
  長崎ブリックホール
- Year and Date
  2016-12-08
- Data Source
  KAKENHI-PROJECT-16K08263
[Presentation] The identification of aging and senescence-related glycoconjugates in human vascular endothelial cells2014
- Author(s)
  Norihiko Sasaki
- Organizer
  18th International Vascular Biology Meeting
- Place of Presentation
  京都市勧業館『みやこめっせ』(京都）
- Data Source
  KAKENHI-PROJECT-24890298
[Presentation] The identification of aging and senescence-related glycoconjugates in human vascular endothelial cells2014
- Author(s)
  Sasaki N and Toyoda M
- Organizer
  18^<th> International Vascular Biology Meeting
- Place of Presentation
  Kyoto
- Data Source
  KAKENHI-PROJECT-24890298

1. Ishiwata Toshiyuki (90203041)

# of Collaborated Projects: 5 results

# of Collaborated Products: 16 results
2. 進士誠一 (80409193)

# of Collaborated Projects: 4 results

# of Collaborated Products: 1 results
3. CHIBA Yumi (10313256)

# of Collaborated Projects: 2 results

# of Collaborated Products: 1 results
4. 石上友章 (50264651)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
5. 志智優樹 (20887187)

# of Collaborated Projects: 2 results

# of Collaborated Products: 8 results
6. ITAKURA Yoko (30582746)

# of Collaborated Projects: 1 results

# of Collaborated Products: 5 results
7. 豊田雅士 (50392486)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
8. 峯岸慎太郎 (80458398)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. 佐々木洋子 (90324110)

# of Collaborated Projects: 1 results

# of Collaborated Products: 14 results
10. 山下純 (80230415)

# of Collaborated Projects: 1 results

# of Collaborated Products: 14 results
11. 五味不二也 (40205620)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
12. 藤田孝之 (40468202)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
13. 宮川繁 (70544237)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
14. 川上恭司郎 (90589227)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
15. NAKASHIMA Rie

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
16. 道下正貴

# of Collaborated Projects: 0 results

# of Collaborated Products: 3 results
17. 村上孝

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

SASAKI NORIHIKO 佐々木 紀彦

SASAKI Norihiko 佐々木 紀彦

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血管内皮細胞由来の細胞外スルファターゼによる老化関連疾患の発症・重症化機構の解明Principal Investigator

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へパラン硫酸脱硫酸化酵素を標的とした老化関連疾患の予防・治療法の開発Principal Investigator

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Elucidation of the cardiovascular network mechanism mediated by senescent vascular endothelial cell-derived factorsPrincipal Investigator

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Basic research for the development of new preventive and therapeutic methods for vascular diseases targeting GM1Principal Investigator

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The clarification of functional roles of glycoconjugates in onset of age- and senescence-related diseasesPrincipal Investigator

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[Book] “細胞老化と糖鎖”, 基礎老化研究誌2022

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SASAKI NORIHIKO 佐々木紀彦

SASAKI Norihiko 佐々木紀彦

[Book] 病理アトラス老化と糖鎖研究2021