Inoshita Hiroyuki 井下博之

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INOSHITA Hiroyuki 井下博之

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Researcher Number	80646117
Other IDs
Affiliation (Current)	2025: 順天堂大学, 医学部, 准教授
Affiliation (based on the past Project Information) *help	2024: 順天堂大学, 医学部, 准教授 2018 – 2019: 順天堂大学, 医学部, 非常勤助教 2014 – 2017: 順天堂大学, 医学部, 助教 2016: 順天堂大学, 医学部, 准教授 2015: 順天堂大学, 医学部, その他
Review Section/Research Field	Principal Investigator Laboratory medicine / Biomedical engineering/Biomaterial science and engineering Except Principal Investigator Basic Section 56050:Otorhinolaryngology-related / Cell biology / Collagenous pathology/Allergology / Laboratory medicine
Keywords	Principal Investigator 制御性T細胞 / 腸腎関連 / ＩｇＡ糖鎖異常 / ＩｇＡ腎症 / 糖鎖異常 / 腸内細菌叢解析 / 粘膜免疫 / IgA腎症 / 慢性腎臓病 / 腸内細菌叢 … More / 次世代型透析膜 / C3a・C5a / 血液透析 / 透析膜 / 生体適合性 / 補体活性化 … More Except Principal Investigator IgA腎症 / 遺伝性血管性浮腫 / シングルセルRNA-sequence / メサンギウム細胞 / Toll-like受容体 / 扁桃 / 新規マーカーの発見 / 透過型電子顕微鏡 / カベオラ / 新規蛋白質の同定 / 質量分析 / fenestration / 糸球体内皮細胞 / アミノペプチダーゼＰ / C4 / C1-inbitor / DPP-IV / アミノペプチダーゼP / アンジオテンシン転換酵素 / ブラジキニン / C1-inhibitor / アポトーシス能 / 抗C1q抗体 / 免疫複合体可溶化能 / オプソニン化能 / 免疫複合体可溶化 / オプソナイゼーション / 自己免疫異常 Less

シングルRNA-seqによるIgA腎症の扁桃における糖鎖異常産生の分子メカニズム
- Principal Investigator
  
  一針幸子
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56050:Otorhinolaryngology-related
- Research Institution
  Juntendo University
The world's first analysis of the intestinal microbiota in IgA nephropathy and an attempt to elucidate the 'intestinal-renal relationship'Principal Investigator
- Principal Investigator
  
  INOSHITA Hiroyuki
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Laboratory medicine
- Research Institution
  Juntendo University
Autoimmune disorder in hereditary angioedema
- Principal Investigator
  
  SATO Nobuyuki
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Laboratory medicine
- Research Institution
  Juntendo University
Studies for the evaluation of bradykinin cleaving enzymes and the establishment of Japanese disease condition of hereditary angioedema
- Principal Investigator
  
  Ohsawa Isao
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Collagenous pathology/Allergology
- Research Institution
  Juntendo University
Identification of compement factor trigger production of C3a and C5a during hemodialysisPrincipal Investigator
- Principal Investigator
  
  INOSHITA Hiroyuki
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Biomedical engineering/Biomaterial science and engineering
- Research Institution
  Juntendo University
Identification of specific protein composes "fenestration" of glomerular endothelial cells
- Principal Investigator
  
  ONDA Kisara
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Cell biology
- Research Institution
  Juntendo University

All 2017 2015 2014

All Journal Article Presentation

[Journal Article] Diminished capacity of opsonization and immune complex solubilization, and detection of anti-C1q antibodies in sera from patients with hereditary angioedema2017
- Author(s)
  Daisuke Honda, Isao Ohsawa, Nobuyuki Sato, Hiroyuki Inoshita, Satoshi Mano, Yasuhiko Tomino and Yusuke Suzuki
- Journal Title
  
  Allergology International
  
  Volume: 印刷中
- NAID
  130006179503
- Peer Reviewed / Acknowledgement Compliant / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26460654
[Journal Article] Diminished capacity of opsonization and immune complex solubilization, and detection of anti-C1q antibodies in sera from patients with hereditary angioedema2017
- Author(s)
  Honda D, Ohsawa I, Sato N, Inoshita H, Mano S, Tomino Y, Suzuki Y
- Journal Title
  
  Allergol. Int.
  
  Volume: 66 Issue: 4 Pages: 603-609
- DOI
  10.1016/j.alit.2017.03.008
- NAID
  130006179503
- ISSN
  1323-8930, 1440-1592
- Language
  English
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-26750151
[Journal Article] Clinical manifestations, diagnosis, and treatment of hereditary angioedema: survey data from 94 physicians in Japan.2015
- Author(s)
  Ohsawa I, Honda D, Nagamachi S, Hisada A, Shimamoto M, Inoshita H, Mano S, Tomino Y.
- Journal Title
  
  Ann Allergy Asthma Immunol.
  
  Volume: 114 Pages: 492-8
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-26750151
[Journal Article] Clinical manifestations, diagnosis, and treatment of hereditary angioedema: survey data from 94 physicians in Japan.2015
- Author(s)
  大澤　勲、本田大介、長町誠嗣、久田温子、島本真実子、井下博之、眞野　訓、富野康日己
- Journal Title
  
  Ann Allergy Asthma Immunol
  
  Volume: 114 Issue: 6 Pages: 492-498
- DOI
  10.1016/j.anai.2015.03.010
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-26461493
[Journal Article] mpact of Body Mass Index on Progression of IgA Nephropathy Among Japanese Patients2014
- Author(s)
  Shimamoto M, Ohsawa I, Suzuki H, Hisada A, Nagamachi S, Honda D, Inoshita H, Shimizu Y, Horikoshi S, Tomino Y
- Journal Title
  
  J Clin Lab Anal
  
  Volume: Aug17 Issue: 5 Pages: 1-8
- DOI
  10.1002/jcla.21778
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-26461238, KAKENHI-PROJECT-26750151
[Journal Article] Properdin has an ascendancy over factor H regulation in complement-mediated renal tubular damage2014
- Author(s)
  長町誠嗣、大澤勲、佐藤信之、他7名
- Journal Title
  
  BMC Nephrol
  
  Volume: 15 Issue: 1 Pages: 82-82
- DOI
  10.1186/1471-2369-15-82
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23591482, KAKENHI-PROJECT-26461238, KAKENHI-PROJECT-26650065
[Journal Article] Clinical and Laboratory Characteristics That Differentiate Hereditary Angioedema in 72 Patients with Angioedema2014
- Author(s)
  Isao Ohsawa, Daisuke Honda, Seiji Nagamachi, Atsuko Hisada, Mamiko Shimamoto, Hiroyuki Inoshita, Satoshi Mano and Yasuhiko Tomino
- Journal Title
  
  Allergol. Int.
  
  Volume: 63 Issue: 4 Pages: 595-602
- DOI
  10.2332/allergolint.14-OA-0700
- NAID
  130004705226
- ISSN
  1323-8930, 1440-1592
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-26460654, KAKENHI-PROJECT-26461493
[Presentation] Differential diagnosis between hereditary and mast cell-mediated angioedema2017
- Author(s)
  大澤　勲、本田大介、久田温子、井下博之、恩田（杖下）紀更、眞野　訓、佐藤信之、堀越　哲
- Organizer
  26th International Complement Workshop
- Place of Presentation
  ホテル日航金沢、金沢
- Year and Date
  2017-09-05
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26461493
[Presentation] The low opsonization and immune complex solubilization ability in sera from HAE patients2015
- Author(s)
  Daisuke Honda, Isao Ohsawa, Nobuyuki Sato, Atsuko Hisada, Hiroyuki Inoshita, Satoshi Mano and Yasuhiko Tomino
- Organizer
  The European Academy of Allergy and. Clinical Immunology
- Place of Presentation
  Spain
- Year and Date
  2015-06-08
- Data Source
  KAKENHI-PROJECT-26460654
[Presentation] Severe Renal Interstitial Fibrosis Can Be a Predictor of Renal Function in Patients with Lupus Nephritis, Especially in Cases With the International Society of Nephrology/Renal Pathology Society Class IV2015
- Author(s)
  D Honda, K Onda-Tsueshita, I. Ohsawa, H. Inoshita, S Horikoshi, Y. Tomino
- Organizer
  Kidney Week 2015 アメリカ腎臓学会
- Place of Presentation
  San Diego, CA
- Year and Date
  2015-11-05
- Data Source
  KAKENHI-PROJECT-26750151
[Presentation] Clinical manifestations, diagnosis and treatment of hereditary angioedema (HAE): survey data from ninety-four physicians in Japan2015
- Author(s)
  大澤　勲、本田大介、久田温子、長町誠嗣、島本真実子、井下博之、堀越　哲、富野康日己
- Organizer
  European Academy of Allergy and Clinical Immunology 2015
- Place of Presentation
  バルセロナ（スペイン）
- Year and Date
  2015-06-06
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26461493
[Presentation] 遺伝性血管性浮腫の臨床的特徴とその診断活用2014
- Author(s)
  大澤　勲、本田大介、久田温子、長町誠嗣、井下博之、島本真実子、富野康日己
- Organizer
  第26回日本アレルギー学会春季臨床大会
- Place of Presentation
  京都
- Year and Date
  2014-05-09
- Data Source
  KAKENHI-PROJECT-26461493
[Presentation] 遺伝性血管性浮腫の臨床的特徴とその診断活用2014
- Author(s)
  大澤勲、本田大介、久田温子、長町誠嗣、井下博之、島本真美子、富野康日己
- Organizer
  日本アレルギー学会
- Place of Presentation
  国立京都国際会館
- Year and Date
  2014-05-09
- Data Source
  KAKENHI-PROJECT-26460654
[Presentation] 遺伝性血管性浮腫における自己免疫異常2014
- Author(s)
  本田大介、大澤勲、佐藤信之、久田温子、島本真美子、井下博之、恩田紀更、堀越哲、富野康日己
- Organizer
  補体研究会
- Place of Presentation
  神戸常磐大学
- Year and Date
  2014-08-23
- Data Source
  KAKENHI-PROJECT-26460654

1. Ohsawa Isao (60407252)

# of Collaborated Projects: 3 results

# of Collaborated Products: 11 results
2. ONDA Kisara (60465044)

# of Collaborated Projects: 3 results

# of Collaborated Products: 4 results
3. TOMINO Yasuhiko (60130077)

# of Collaborated Projects: 2 results

# of Collaborated Products: 6 results
4. SATO Nobuyuki (70621944)

# of Collaborated Projects: 1 results

# of Collaborated Products: 4 results
5. HONDA Daisuke (50790094)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
6. 一針幸子 (30327803)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. 池田勝久 (70159614)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. 尾崎心 (10754765)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. 井下綾子 (00514762)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. KUSABA Gaku

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. NAGAMACHI Seiji

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
12. 清水芳男

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Inoshita Hiroyuki 井下 博之

INOSHITA Hiroyuki 井下 博之

Research Projects

Research Products

Co-Researchers

シングルRNA-seqによるIgA腎症の扁桃における糖鎖異常産生の分子メカニズム

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

The world's first analysis of the intestinal microbiota in IgA nephropathy and an attempt to elucidate the 'intestinal-renal relationship'Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Autoimmune disorder in hereditary angioedema

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Studies for the evaluation of bradykinin cleaving enzymes and the establishment of Japanese disease condition of hereditary angioedema

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Identification of compement factor trigger production of C3a and C5a during hemodialysisPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Identification of specific protein composes "fenestration" of glomerular endothelial cells

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Diminished capacity of opsonization and immune complex solubilization, and detection of anti-C1q antibodies in sera from patients with hereditary angioedema2017

Author(s)

Journal Title

NAID

Data Source

[Journal Article] Diminished capacity of opsonization and immune complex solubilization, and detection of anti-C1q antibodies in sera from patients with hereditary angioedema2017

Author(s)

Journal Title

DOI

NAID

ISSN

Language

Data Source

[Journal Article] Clinical manifestations, diagnosis, and treatment of hereditary angioedema: survey data from 94 physicians in Japan.2015

Author(s)

Journal Title

Data Source

[Journal Article] Clinical manifestations, diagnosis, and treatment of hereditary angioedema: survey data from 94 physicians in Japan.2015

Author(s)

Journal Title

DOI

Data Source

[Journal Article] mpact of Body Mass Index on Progression of IgA Nephropathy Among Japanese Patients2014

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Properdin has an ascendancy over factor H regulation in complement-mediated renal tubular damage2014

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Clinical and Laboratory Characteristics That Differentiate Hereditary Angioedema in 72 Patients with Angioedema2014

Author(s)

Journal Title

DOI

NAID

ISSN

Language

Inoshita Hiroyuki 井下博之

INOSHITA Hiroyuki 井下博之