Ninagawa Satoshi 蜷川暁

Researcher Number	80647991
Other IDs	https://orcid.org/0000-0002-8005-4716
Affiliation (Current)	2025: 神戸大学, バイオシグナル総合研究センター, 助教
Affiliation (based on the past Project Information) *help	2021 – 2024: 神戸大学, バイオシグナル総合研究センター, 助教 2017 – 2020: 京都大学, 理学研究科, 特定助教 2016: 京都大学, 理学研究科, 特定研究員 2015: 京都大学, 理学(系)研究科(研究院), 研究員 2014: 大学共同利用機関法人自然科学研究機構(岡崎共通研究施設), 岡崎統合バイオサイエンスセンター, 特別協力研究員
Review Section/Research Field	Principal Investigator Cell biology / Basic Section 44010:Cell biology-related Except Principal Investigator Medium-sized Section 43:Biology at molecular to cellular levels, and related fields / Biological Sciences
Keywords	Principal Investigator 糖鎖 / 小胞体関連分解 / 構造異常タンパク質 / マンノーストリミング / 小胞体 / mannose trimming / EDEM / OS-9/XTP3B / オルガネラゾーン / XTP3B … More / OS-9 / レクチン / N型糖鎖 / タンパク質分解 / ERAD / N-glycan / mannose … More Except Principal Investigator オルガネラ / 構造異常の度合い / 小胞体関連分解 / 応答 / 選別 / 小胞輸送 / ゴルジ体 / 超解像顕微鏡 / 小胞体ストレス / タンパク質分解 / 輸送 / 小胞体 / オルガネラ・ゾーン Less

哺乳動物の小胞体関連分解における小胞体内イベントの全容解明
- Principal Investigator
  
  森和俊
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Review Section
  
  Medium-sized Section 43:Biology at molecular to cellular levels, and related fields
- Research Institution
  Kyoto University
Analysis of how misfolded proteins are delivered to retrotranslocation complex for ER-associated degradationPrincipal Investigator
- Principal Investigator
  
  Ninagawa Satoshi
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 44010:Cell biology-related
- Research Institution
  Kyoto University
Analysis of sorting zones involved in protein quality control in the endoplasmic reticulum
- Principal Investigator
  
  Mori Kazutoshi
- Project Period (FY)
  2017 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Review Section
  
  Biological Sciences
- Research Institution
  Kyoto University
Insight into how severely misfolded proteins are degraded in the ERPrincipal Investigator
- Principal Investigator
  
  Ninagawa Satoshi
- Project Period (FY)
  2016 – 2017
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Cell biology
- Research Institution
  Kyoto University
Analysis of ER-associated degradation components by multiple knockout cell lines using TALENPrincipal Investigator
- Principal Investigator
  
  Ninagawa Satoshi
- Project Period (FY)
  2014 – 2015
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Cell biology
- Research Institution
  Kyoto University
  Okazaki Research Facilities, National Institutes of Natural Sciences

All 2021 2020 2019 2018 2017 2016 2015 2014 Other

All Journal Article Presentation

[Journal Article] Mechanisms of productive folding and endoplasmic reticulum-associated degradation of glycoproteins and non-glycoproteins.2021
- Author(s)
  Ninagawa S, George G, Mori K
- Journal Title
  
  Biochim Biophys Acta Gen Subj.
  
  Volume: 1865 Issue: 3 Pages: 129812-129812
- DOI
  10.1016/j.bbagen.2020.129812
- NAID
  120006954900
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PLANNED-17H06419, KAKENHI-PROJECT-18K06216
[Journal Article] Purified EDEM3 or EDEM1 alone produces determinant oligosaccharide structures from M8B in mammalian glycoprotein ERAD2021
- Author(s)
  George Ginto、Ninagawa Satoshi、Yagi Hirokazu、Furukawa Jun-ichi、Hashii Noritaka、Ishii-Watabe Akiko、Deng Ying、Matsushita Kazutoshi、Ishikawa Tokiro、Mamahit Yugoviandi P、Maki Yuta、Kajihara Yasuhiro、Kato Koichi、Okada Tetsuya、Mori Kazutoshi
- Journal Title
  
  eLife
  
  Volume: 10
- DOI
  10.7554/elife.70357
- NAID
  120007167291
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PLANNED-17H06414, KAKENHI-PLANNED-17H06419, KAKENHI-ORGANIZER-17H06413, KAKENHI-PROJECT-23K21358
[Journal Article] Reinvestigation of Disulfide-bonded Oligomeric Forms of the Unfolded Protein Response Transducer ATF62020
- Author(s)
  Koba Hibiki、Jin Shengyu、Imada Nanami、Ishikawa Tokiro、Ninagawa Satoshi、Okada Tetsuya、Sakuma Tetsushi、Yamamoto Takashi、Mori Kazutoshi
- Journal Title
  
  Cell Struct. Funct.
  
  Volume: 45 Issue: 1 Pages: 9-21
- DOI
  10.1247/csf.19030
- NAID
  130007792116
- ISSN
  0386-7196, 1347-3700
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K06658, KAKENHI-PROJECT-19K16111, KAKENHI-ORGANIZER-17H06413, KAKENHI-PROJECT-17H01432, KAKENHI-PROJECT-18K06216
[Journal Article] EDEM2 stably disulfide-bonded to TXNDC11 catalyzes the first mannose trimming step in mammalian glycoprotein ERAD2020
- Author(s)
  George Ginto、Ninagawa Satoshi、Yagi Hirokazu、Saito Taiki、Ishikawa Tokiro、Sakuma Tetsushi、Yamamoto Takashi、Imami Koshi、Ishihama Yasushi、Kato Koichi、Okada Tetsuya、Mori Kazutoshi
- Journal Title
  
  eLife
  
  Volume: 9
- DOI
  10.7554/elife.53455
- NAID
  120006817590
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K06110, KAKENHI-PROJECT-19K06658, KAKENHI-PROJECT-19K16111, KAKENHI-ORGANIZER-17H06413, KAKENHI-PLANNED-17H06419, KAKENHI-PROJECT-17H01432, KAKENHI-PROJECT-18K06216, KAKENHI-PLANNED-17H06414
[Journal Article] Improved secretion of glycoproteins using an N-glycan-restricted passport sequence tag recognized by cargo receptor2020
- Author(s)
  Yagi Hirokazu、Yagi-Utsumi Maho、Honda Rena、Ohta Yusaku、Saito Taiki、Nishio Miho、Ninagawa Satoshi、Suzuki Kousuke、Anzai Takahiro、Kamiya Yukiko、Aoki Kazuhiro、Nakanishi Mahito、Satoh Tadashi、Kato Koichi
- Journal Title
  
  Nature Communications
  
  Volume: 11 Issue: 1 Pages: 1-9
- DOI
  10.1038/s41467-020-15192-1
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-19H05798, KAKENHI-PROJECT-18H02444, KAKENHI-PROJECT-19H03361, KAKENHI-PROJECT-16H06280, KAKENHI-PROJECT-18K08443, KAKENHI-ORGANIZER-19H05794, KAKENHI-PROJECT-18K06216, KAKENHI-PLANNED-17H06414
[Journal Article] Antipsychotic olanzapine-induced misfolding of proinsulin in the endoplasmic reticulum accounts for atypical development of diabetes2020
- Author(s)
  Ninagawa Satoshi、Tada Seiichiro、Okumura Masaki、Inoguchi Kenta、Kinoshita Misaki、Kanemura Shingo、Imami Koshi、Umezawa Hajime、Ishikawa Tokiro、Mackin Robert B、Torii Seiji、Ishihama Yasushi、Inaba Kenji、Anazawa Takayuki、Nagamine Takahiko、Mori Kazutoshi
- Journal Title
  
  eLife
  
  Volume: 9 Pages: 23-31
- DOI
  10.7554/elife.60970
- NAID
  120006898101
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K06658, KAKENHI-PROJECT-19K16092, KAKENHI-PLANNED-17H06419, KAKENHI-PUBLICLY-20H05310, KAKENHI-PROJECT-18H03978, KAKENHI-PROJECT-20H03241, KAKENHI-PROJECT-17K08528, KAKENHI-PROJECT-18K06216, KAKENHI-ORGANIZER-17H06413
[Journal Article] Development of a Rapid <i>in vivo</i> Assay to Evaluate the Efficacy of IRE1-specific Inhibitors of the Unfolded Protein Response Using Medaka Fish2019
- Author(s)
  Jin Byungseok、Ishikawa Tokiro、Taniguchi Mai、Ninagawa Satoshi、Okada Tetsuya、Kagaya Shigehide、Mori Kazutoshi
- Journal Title
  
  Cell Struct. Funct.
  
  Volume: 45 Issue: 1 Pages: 23-31
- DOI
  10.1247/csf.19032
- NAID
  130007795672
- ISSN
  0386-7196, 1347-3700
- Language
  English
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K06658, KAKENHI-ORGANIZER-17H06413, KAKENHI-PROJECT-17H01432, KAKENHI-PROJECT-18J14647, KAKENHI-PROJECT-18K06216
[Journal Article] UPR Transducer BBF2H7 Allows Export of Type II Collagen in a Cargo- and Developmental Stage-Specific Manner2017
- Author(s)
  Tokiro Ishikawa, Takuya Toyama, Yuki Nakamura, Kentaro Tamada, Hitomi Shimizu, Satoshi Ninagawa, Tetsuya Okada, Yasuhiro Kamei, Tomoko Ishikawa-Fujiwara, Takeshi Todo, Eriko Aoyama, Masaharu Takigawa, Akihiro Harada and Kazutoshi Mori
- Journal Title
  
  Journal of cell biology
  
  Volume: 印刷中 Issue: 6 Pages: 1761-1774
- DOI
  10.1083/jcb.201609100
- NAID
  120006343784
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-15K18529, KAKENHI-PROJECT-17K15116, KAKENHI-PROJECT-15H05713, KAKENHI-PROJECT-17H01432, KAKENHI-PROJECT-15H04668, KAKENHI-PROJECT-15H05014, KAKENHI-PROJECT-15K11038, KAKENHI-PROJECT-16K18538, KAKENHI-PLANNED-17H06422
[Journal Article] SEL1L-dependent Substrates Require Derlin2/3 and Herp1/2 for Endoplasmic Reticulum-associated Degradation2017
- Author(s)
  Takehiro Sugimoto, Satoshi Ninagawa, Shimpei Yamano, Tokiro Ishikawa, Tetsuya Okada, Shunichi Takeda, Kazutoshi Mori
- Journal Title
  
  Cell Struct. Funct.
  
  Volume: 42 Issue: 2 Pages: 81-94
- DOI
  10.1247/csf.17007
- NAID
  130005708193
- ISSN
  0386-7196, 1347-3700
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K15116, KAKENHI-PROJECT-16H06306, KAKENHI-PROJECT-17H01432, KAKENHI-PROJECT-15K06996, KAKENHI-PROJECT-16K18538
[Journal Article] Direct mapping of additional modifications on phosphorylated O-glycans of α-dystroglycan by mass spectrometry analysis in conjunction with knocking out of causative genes for dystroglycanopathy2016
- Author(s)
  H.Yagi, C.-W.Kuo, T.Obayashi, S.Ninagawa, K.-H.Khoo, and K.Kato
- Journal Title
  
  Mol. Cell Proteomics
  
  Volume: 15 Issue: 11 Pages: 3424-3434
- DOI
  10.1074/mcp.m116.062729
- Peer Reviewed / Acknowledgement Compliant / Int'l Joint Research
- Data Source
  KAKENHI-ORGANIZER-25102001, KAKENHI-PLANNED-25102008, KAKENHI-PROJECT-15K07935, KAKENHI-PROJECT-16K18538, KAKENHI-INTERNATIONAL-15K21708
[Journal Article] 糖鎖依存的構造異常タンパク質分解に必須な糖鎖刈り込み機構を解明革新的ゲノム編集技術によって従来のモデルを一新2015
- Author(s)
  蜷川　暁、加藤　晃一、森　和俊
- Journal Title
  
  化学と生物
  
  Volume: Vol.53, No.9 Pages: 571-573
- NAID
  130005405061
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26840065
[Journal Article] Forcible destruction of severely misfolded mammalian glycoproteins by the non-glycoprotein ERAD pathway.2015
- Author(s)
  Ninagawa S, Okada T, Sumitomo Y, Horimoto S, Sugimoto T, Ishikawa T, Takeda S, Yamamoto T, Suzuki T, Kamiya Y, Kato K, Mori K.
- Journal Title
  
  The Journal of Cellular Biology
  
  Volume: 211 Issue: 4 Pages: 775-784
- DOI
  10.1083/jcb.201504109
- NAID
  120005672576
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-15K06996, KAKENHI-PROJECT-15K18529, KAKENHI-ORGANIZER-25102001, KAKENHI-PLANNED-25102008, KAKENHI-PUBLICLY-26110725, KAKENHI-PROJECT-23221005, KAKENHI-PROJECT-26840065, KAKENHI-PROJECT-26291040
[Journal Article] EDEM2 initiates mammalian glycoprotein ERAD by catalyzing the first mannose trimming step.2014
- Author(s)
  Ninagawa S, Okada T, Sumitomo Y, Kamiya Y, Kato K, Horimoto S, Ishikawa T, Takeda S, Sakuma T, Yamamoto T, Mori K
- Journal Title
  
  J Cell Biol.
  
  Volume: 206 Issue: 3 Pages: 347-356
- DOI
  10.1083/jcb.201404075
- NAID
  120005468381
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-23221005, KAKENHI-PROJECT-24249002, KAKENHI-ORGANIZER-25102001, KAKENHI-PLANNED-25102008, KAKENHI-PROJECT-25890014, KAKENHI-PROJECT-26840065
[Presentation] 第二世代抗精神病薬オランザピンは、膵ベータ細胞において、小胞体でのプロインスリンの構造形成阻害と、それに伴う分解を誘発し、非典型的な糖尿病を惹起する2021
- Author(s)
  蜷川暁、多田誠一郎、奥村正樹、井ノ口健太、木下岬、金村進吾、今見考志、梅澤元、石川時郎、Robert Mackin、鳥居征司、石濱泰、稲葉謙次、穴澤貴行、長嶺敬彦、森和俊
- Organizer
  日本薬学会　第141年会
- Data Source
  KAKENHI-PROJECT-18K06216
[Presentation] EDEM2酵素活性発揮には、TXNDC11とのジスルフィド結合形成が必要である2020
- Author(s)
  蜷川　暁、Ginto George、矢木　宏和、斎藤　泰輝、住友　嘉樹、石川　時郎、佐久間　哲史、山本　卓、今見　考志、石濱　泰、加藤　晃一、岡田　徹也、森　和俊
- Organizer
  第39回　日本糖質学会年会
- Data Source
  KAKENHI-PROJECT-18K06216
[Presentation] EDEM2酵素活性発揮には、TXNDC11とのジスルフィド結合形成が必要である2020
- Author(s)
  蜷川暁、Ginto George、矢木宏和、斎藤泰輝、住友嘉樹、石川時郎、佐久間哲史、山本卓、今見考志、石濱泰、加藤晃一、岡田徹也、森和俊
- Organizer
  第39回　日本糖質学会年会
- Data Source
  KAKENHI-PLANNED-17H06419
[Presentation] 抗精神病薬オランザピンは、副作用としてプロインスリンのミスフォールディングとその分解を惹起する2020
- Author(s)
  蜷川暁
- Organizer
  第43回日本分子生物学会年会
- Data Source
  KAKENHI-PLANNED-17H06419
[Presentation] 遺伝子破壊法を用いた小胞体関連分解機構の解明2020
- Author(s)
  蜷川　暁
- Organizer
  第93回　日本生化学会大会
- Invited
- Data Source
  KAKENHI-PROJECT-18K06216
[Presentation] 抗精神病薬オランザピンは、副作用としてプロインスリンのミスフォールディングとその分解を惹起する2020
- Author(s)
  蜷川　暁
- Organizer
  第43回　分子生物学会年会
- Invited
- Data Source
  KAKENHI-PROJECT-18K06216
[Presentation] 抗精神病薬オランザピンによって , プロインスリンは分子間ジスルフィド結合を介した構造異常が誘発され , 小胞体関連分解によって処理される2020
- Author(s)
  蜷川暁、多田誠一郎、奥村正樹、井ノ口健太、木下岬、金村進吾、今見考志、梅沢元、石川時郎、岡田徹也、Robert Mackin、鳥居征司、石濱泰、稲葉謙次、穴澤貴行、長嶺敬彦、森和俊
- Organizer
  第72回日本細胞生物学会大会
- Data Source
  KAKENHI-PLANNED-17H06419
[Presentation] 抗精神病薬オランザピンによって , プロインスリンは分子間ジスルフィド結合を介した構造異常が誘発され , 小胞体関連分解によって処理される2020
- Author(s)
  蜷川暁、多田誠一郎、奥村正樹、井ノ口健太、木下岬、金村進吾、今見考志、梅沢元、石川時郎、岡田徹也、Robert Mackin、鳥居征司、石濱泰、稲葉謙次、穴澤貴行、長嶺敬彦、森和俊
- Organizer
  第72回　日本細胞生物学会大会
- Data Source
  KAKENHI-PROJECT-18K06216
[Presentation] 小胞体タンパク質品質管理機構の中心を担うN型糖鎖依存／非依存小胞体関連分解経路の分子メカニズムの解析2019
- Author(s)
  蜷川　暁、Ginto George、矢木　宏和、今見　考志、石濱　泰、石川　時郎、佐久間　哲史、山本　卓、武田　俊一、加藤　晃一、岡田　徹也、森　和俊
- Organizer
  第42回　日本分子生物学会年会
- Invited
- Data Source
  KAKENHI-PROJECT-18K06216
[Presentation] 高等動物における N 型糖鎖トリミングを基軸とした小胞体関連分解機構の解析2019
- Author(s)
  蜷川暁、Ginto George、矢木宏和、住友嘉樹、神谷由紀子、石川時郎、武田俊一、佐久間哲史、山本卓、加藤晃一、岡田徹也、森和俊
- Organizer
  第38回　日本糖質学会年会
- Data Source
  KAKENHI-PROJECT-18K06216
[Presentation] The antipsychotic olanzapine targets proinsulin for endoplasmic reticulum-associated degradation in a pancreatic β cell line2018
- Author(s)
  Satoshi Ninagawa, Tetsuya Okada, Imami Koshi, Hajime Umezawa, Tokiro Ishikawa, Seiji Torii, Robert B. Mackin, Yasushi Ishihama, Takahiko Nagamine and Kazutoshi Mori
- Organizer
  京都産業大学タンパク質動態研究所・新学術領域「新生鎖の生物学」合同国際シンポジウムProteins: From the Cradle to the Grave
- Data Source
  KAKENHI-PROJECT-18K06216
[Presentation] 第二世代抗精神病薬オランザピンがインスリン分泌不全を引き起こし、糖尿病を誘起する分子メカニズムの解析2018
- Author(s)
  Satoshi Ninagawa, Tetsuya Okada, Koshi Imami, Hajime Umezawa, Tokiro Ishikawa, Seiji Torii, Robert B. Mackin, Yasushi Ishihama, Takahiko Nagamine and Kazutoshi Mori
- Organizer
  第91回　日本生化学会大会
- Data Source
  KAKENHI-PROJECT-18K06216
[Presentation] ヒト遺伝子破壊株を用いた小胞体関連分解レクチン因子OS-9、XTP3Bの機能解析2018
- Author(s)
  蜷川　暁、杉本　岳大、小野田麻由、岡田　徹也、石川　時郎、佐久間　哲史、山本　卓、森　和俊
- Organizer
  第３７回日本糖質学会年会
- Data Source
  KAKENHI-PROJECT-18K06216
[Presentation] 第二世代抗精神病薬オランザピンが、副作用として糖尿病を引き起こす分子メカニズムの解析～インスリンは、適切なジスルフィド結合形成を阻害され、小胞体関連分解により処理される～2017
- Author(s)
  Satoshi Ninagawa, Tetsuya Okada, Hajime Umezawa, Tokiro Ishikawa, Seiji Torii, Robert B. Mackin, Takahiko Nagamine, and Kazutoshi Mori
- Organizer
  ConBio2017
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K18538
[Presentation] EDEM1/2/3 are α1,2-mannosidases essential for endoplasmic reticulum-associated degradation of glycoproteins
- Author(s)
  Satoshi Ninagawa, Tetsuya Okada, Yoshiki Sumitomo, Yukiko Kamiya, Satoshi Horimoto, Tokiro Ishikawa, Shunichi Takeda, Tetsushi Sakuma, Takashi Yamamoto, Koichi Kato, Kazutoshi Mori
- Organizer
  SFG JSCR Joint Meeting
- Place of Presentation
  Hawaii, USA
- Year and Date
  2014-11-16 – 2014-11-19
- Data Source
  KAKENHI-PROJECT-26840065
[Presentation] 小胞体で新生タンパク質に付加されたN型糖鎖からのマンノーストリミングはEDEM2によって開始される
- Author(s)
  蜷川暁、岡田徹也、住友嘉樹、神谷由紀子、堀本賢、石川時郎、武田俊一、佐久間哲史、山本卓、加藤晃一、森和俊
- Organizer
  第33回日本糖質学会
- Place of Presentation
  愛知県名古屋市　名古屋大学
- Year and Date
  2014-08-10 – 2014-08-12
- Data Source
  KAKENHI-PROJECT-26840065

1. Mori Kazutoshi (70182194)

# of Collaborated Projects: 2 results

# of Collaborated Products: 3 results
2. 尾野雅哉 (00270900)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
3. 西頭英起 (00332627)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
4. 片桐豊雅 (60291895)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
5. 名黒功 (80401222)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. YAGI Hirokazu

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
7. AOKI Kazuhiro

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
8. 石川時郎

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
9. 岡田徹也

# of Collaborated Projects: 0 results

# of Collaborated Products: 3 results
10. 武田俊一

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
11. 加藤晃一

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Ninagawa Satoshi 蜷川 暁

Research Projects

Research Products

Co-Researchers

哺乳動物の小胞体関連分解における小胞体内イベントの全容解明

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Analysis of how misfolded proteins are delivered to retrotranslocation complex for ER-associated degradationPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Analysis of sorting zones involved in protein quality control in the endoplasmic reticulum

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Insight into how severely misfolded proteins are degraded in the ERPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Analysis of ER-associated degradation components by multiple knockout cell lines using TALENPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Mechanisms of productive folding and endoplasmic reticulum-associated degradation of glycoproteins and non-glycoproteins.2021

Author(s)

Journal Title

DOI

NAID

Data Source

[Journal Article] Purified EDEM3 or EDEM1 alone produces determinant oligosaccharide structures from M8B in mammalian glycoprotein ERAD2021

Author(s)

Journal Title

DOI

NAID

Data Source

[Journal Article] Reinvestigation of Disulfide-bonded Oligomeric Forms of the Unfolded Protein Response Transducer ATF62020

Author(s)

Journal Title

DOI

NAID

ISSN

Language

Data Source

[Journal Article] EDEM2 stably disulfide-bonded to TXNDC11 catalyzes the first mannose trimming step in mammalian glycoprotein ERAD2020

Author(s)

Journal Title

DOI

NAID

Data Source

[Journal Article] Improved secretion of glycoproteins using an N-glycan-restricted passport sequence tag recognized by cargo receptor2020

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Antipsychotic olanzapine-induced misfolding of proinsulin in the endoplasmic reticulum accounts for atypical development of diabetes2020

Author(s)

Journal Title

DOI

NAID

Data Source

[Journal Article] Development of a Rapid <i>in vivo</i> Assay to Evaluate the Efficacy of IRE1-specific Inhibitors of the Unfolded Protein Response Using Medaka Fish2019

Author(s)

Journal Title

DOI

NAID

ISSN

Language

Data Source

[Journal Article] UPR Transducer BBF2H7 Allows Export of Type II Collagen in a Cargo- and Developmental Stage-Specific Manner2017

Ninagawa Satoshi 蜷川暁

[Journal Article] 糖鎖依存的構造異常タンパク質分解に必須な糖鎖刈り込み機構を解明革新的ゲノム編集技術によって従来のモデルを一新2015