Nomura Takushi 野村拓志

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NOMURA Takushi 野村拓志

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Researcher Number	80711001
Other IDs
Affiliation (Current)	2025: 熊本大学, ヒトレトロウイルス学共同研究センター, 講師
Affiliation (based on the past Project Information) *help	2021 – 2024: 熊本大学, ヒトレトロウイルス学共同研究センター, 講師 2019 – 2020: 国立感染症研究所, エイズ研究センター, 主任研究官 2016 – 2017: 熊本大学, エイズ学研究センター, 特定事業研究員 2013 – 2015: 国立感染症研究所, その他部局等, 研究員
Review Section/Research Field	Principal Investigator Basic Section 49060:Virology-related / Virology Except Principal Investigator Basic Section 54030:Infectious disease medicine-related / Medium-sized Section 58:Society medicine, nursing, and related fields
Keywords	Principal Investigator 複製制御 / CTL / SIV / 免疫ドミナンシー / HIV / サルエイズモデル / 動物モデル / 重症化機序 / SARS-CoV-2 / 老化 … More / 免疫 / MHC-I / ウイルス特異的CTL / 変異選択 / エピトープ領域 / 複製非制御個体 / 交差反応性 / プロウイルス / 逃避変異 / Latent Reservoir / 国際情報交換 / CTL逃避変異 / 複製制御維持機構解析 / 免疫動態解析 / 宿主免疫応答 / 複製抑制維持 / CTL逃避変異選択 / 新規CTLエピトープ決定 / エイズウイルス … More Except Principal Investigator SARS-CoV-2 / 新型コロナウイルス / COVID-19 Less

T細胞免疫老化によるSARS-CoV-2重症化機序の動物モデルを用いた解明Principal Investigator
- Principal Investigator
  
  野村拓志
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 49060:Virology-related
- Research Institution
  Kumamoto University
Impact of cross-reactive immunity to pre-existing infections on COVID-19 pathogenesis in East Africa
- Principal Investigator
  
  上野貴将
- Project Period (FY)
  2022 – 2025
- Research Category
  
  Fund for the Promotion of Joint International Research (Fostering Joint International Research (B))
- Review Section
  
  Medium-sized Section 58:Society medicine, nursing, and related fields
- Research Institution
  Kumamoto University
Investigation for potential CTL epitopes spanning various coronavirues aiming for universal vaccine development
- Principal Investigator
  
  上野貴将
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 54030:Infectious disease medicine-related
- Research Institution
  Kumamoto University
Analysis of CD8+T-cell dominance in SIV progressorPrincipal Investigator
- Principal Investigator
  
  Nomura Takushi
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 49060:Virology-related
- Research Institution
  Kumamoto University
Analysis of cross-reactivity of dominant SIV-specific CD8+T cells associate with viral control in SIV infected Burmese rhesus macaque.Principal Investigator
- Principal Investigator
  
  Nomura Takushi
- Project Period (FY)
  2019 – 2020
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 49060:Virology-related
- Research Institution
  National Institute of Infectious Diseases
Analysis of latent reservoir in SIV controllesPrincipal Investigator
- Principal Investigator
  
  Nomura Takushi
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Virology
- Research Institution
  Kumamoto University
  National Institute of Infectious Diseases
Mechanism analysis of lasting of AIDS virus control with SIV controllers.Principal Investigator
- Principal Investigator
  
  NOMURA Takushi
- Project Period (FY)
  2013 – 2014
- Research Category
  
  Grant-in-Aid for Research Activity Start-up
- Research Field
  
  Virology
- Research Institution
  National Institute of Infectious Diseases

All 2023 2022 2021 2020 2019 2017 2016 2015 2014 2013 Other

All Journal Article Presentation Book

[Book] 実験医学　別冊　2016 Vol.34 No.132016
- Author(s)
  野村拓志、俣野哲朗
- Total Pages
  6
- Publisher
  羊土社
- Data Source
  KAKENHI-PROJECT-15K19119
[Journal Article] HTLV-1 Proliferation after CD8 + Cell Depletion by Monoclonal Anti-CD8 Antibody Administration in Latently HTLV-1-Infected Cynomolgus Macaques2023
- Author(s)
  Midori Nakamura-Hoshi, Takushi Nomura, Masako Nishizawa, Trang Thi Thu Hau, Hiroyuki Yamamoto, Midori Okazaki, Hiroshi Ishii, Kenzo Yonemitsu, Yuriko Suzaki, Yasushi Ami, and Tetsuro Matano
- Journal Title
  
  Microbiology Spectrum
  
  Volume: 11(4) Issue: 4
- DOI
  10.1128/spectrum.01518-23
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K07061, KAKENHI-PROJECT-21H02745
[Journal Article] Env-independent protection of intrarectal SIV challenge by vaccine induction of Gag/Vif-specific CD8+ T cells but not CD4+ T cells2022
- Author(s)
  Ishii Hiroshi、Terahara Kazutaka、Nomura Takushi、Okazaki Midori、Yamamoto Hiroyuki、Shu Tsugumine、Sakawaki Hiromi、Miura Tomoyuki、Watkins David I.、Matano Tetsuro
- Journal Title
  
  Molecular Therapy
  
  Volume: 30 Issue: 5 Pages: 2048-2057
- DOI
  10.1016/j.ymthe.2022.02.023
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K07061, KAKENHI-PROJECT-21H02745
[Journal Article] Hierarchy of multiple viral CD8+ T-cell epitope mutations in sequential selection in simian immunodeficiency infection2022
- Author(s)
  Ntim Nana Afia Asante、Ishii Hiroshi、Jomori Moe、Yamamoto Hiroyuki、Matano Tetsuro、Nomura Takushi
- Journal Title
  
  Biochemical and Biophysical Research Communications
  
  Volume: 607 Pages: 124-130
- DOI
  10.1016/j.bbrc.2022.03.108
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21H02745, KAKENHI-PROJECT-21K07061
[Journal Article] Late-phase dominance of a single epitope-specific CD8+ T-cell response in passive neutralizing antibody-infused simian immunodeficiency virus controllers2021
- Author(s)
  Kanno Yoshiaki、Hau Trang Thi Thu、Kurokawa Rise、Nomura Takushi、Nishizawa Masako、Matano Tetsuro、Yamamoto Hiroyuki
- Journal Title
  
  AIDS
  
  Volume: 35 Issue: 14 Pages: 2281-2288
- DOI
  10.1097/qad.0000000000003013
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21H02745, KAKENHI-PROJECT-21K07061
[Journal Article] A Novel Immunogen Selectively Eliciting CD8(+) T Cells but Not CD4(+) T Cells Targeting Immunodeficiency Virus Antigens.2020
- Author(s)
  Ishii H, Terahara K, Nomura T, Takeda A, Okazaki M, Yamamoto H, Tokusumi T, Shu T, Matano T.
- Journal Title
  
  Journal of Virology
  
  Volume: 94 Issue: 8
- DOI
  10.1128/jvi.01876-19
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K07157, KAKENHI-PROJECT-19K16679, KAKENHI-PROJECT-18H02666
[Journal Article] Therapeutic vaccine-mediated Gag-specific CD8+ T-cell induction under anti-retroviral therapy augments anti-virus efficacy of CD8+ cells in simian immunodeficiency virus-infected macaques2020
- Author(s)
  Nakamura-Hoshi Midori、Takahara Yusuke、Matsuoka Saori、Ishii Hiroshi、Seki Sayuri、Nomura Takushi、Yamamoto Hiroyuki、Sakawaki Hiromi、Miura Tomoyuki、Tokusumi Tsuyoshi、Shu Tsugumine、Matano Tetsuro
- Journal Title
  
  Scientific Reports
  
  Volume: 10 Issue: 1 Pages: 11394-11394
- DOI
  10.1038/s41598-020-68267-w
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18H02666, KAKENHI-PROJECT-19H03146, KAKENHI-PROJECT-18K07157, KAKENHI-PROJECT-18K15175, KAKENHI-PROJECT-19K16679
[Journal Article] CD8+ T cell-based strong selective pressure on multiple simian immunodeficiency virus targets in macaques possessing a protective MHC class I haplotype2019
- Author(s)
  Hau Trang Thi Thu、Nakamura-Hoshi Midori、Kanno Yoshiaki、Nomura Takushi、Nishizawa Masako、Seki Sayuri、Ishii Hiroshi、Kawana-Tachikawa Ai、Hall William W.、Nguyen Thi Lan Anh、Matano Tetsuro、Yamamoto Hiroyuki
- Journal Title
  
  Biochemical and Biophysical Research Communications
  
  Volume: 512 Issue: 2 Pages: 213-217
- DOI
  10.1016/j.bbrc.2019.03.003
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K07157, KAKENHI-PROJECT-18K15175, KAKENHI-PROJECT-17H02185, KAKENHI-PROJECT-19K16679, KAKENHI-PROJECT-18H02666
[Journal Article] In vivo virulence of MHC-adapted AIDS virus serially-passaged through MHC-mismatched hosts2017
- Author(s)
  Seki Sayuri、Nomura Takushi、Nishizawa Masako、Yamamoto Hiroyuki、Ishii Hiroshi、Matsuoka Saori、Shiino Teiichiro、Sato Hironori、Mizuta Kazuta、Sakawaki Hiromi、Miura Tomoyuki、Naruse Taeko K.、Kimura Akinori、Matano Tetsuro
- Journal Title
  
  PLOS Pathogens
  
  Volume: 13 Issue: 9 Pages: e1006638-e1006638
- DOI
  10.1371/journal.ppat.1006638
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15H04737, KAKENHI-PROJECT-16H04682, KAKENHI-PROJECT-17H02185, KAKENHI-PROJECT-15K19119
[Journal Article] Association of lymph-node antigens with lower Gag-specific central-memory and higher Env-specific effector-memory CD8+ T-cell frequencies in a macaque AIDS model2016
- Author(s)
  Ishii H, Matsuoka S, Nomura T, Nakamura M, Shiino T, Sato Y, Iwata-Yoshikawa N, Hasegawa H, Mizuta K, Sakawaki H, Miura T, Koyanagi Y, Naruse TK, Kimura A, Matano T
- Journal Title
  
  Sci Rep
  
  Volume: 6 Issue: 1 Pages: 30153-30153
- DOI
  10.1038/srep30153
- NAID
  120006346255
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PUBLICLY-15H01271, KAKENHI-PLANNED-24115008, KAKENHI-PROJECT-15H04737, KAKENHI-PROJECT-16H04682, KAKENHI-PROJECT-15K19119
[Journal Article] Biphasic CD8+ T-cell defense in elite SIV control by acute-phase passive neutralizing antibody immunization2016
- Author(s)
  Iseda S, Takahashi N, Poplimont H, Nomura T, Seki S, Nakane T, Nakamura M, Shi S, Ishii H, Furukawa S, Harada S, Naruse TK, Kimura A, Matano T, Yamamoto H
- Journal Title
  
  J Virol
  
  Volume: 90 Issue: 14 Pages: 6276-6290
- DOI
  10.1128/jvi.00557-16
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-15H01271, KAKENHI-PROJECT-15H04737, KAKENHI-PROJECT-15K08125, KAKENHI-PROJECT-15K19119
[Journal Article] Augmentation of anti-simian immunodeficiency virus activity in CD8+ cells by neutralizing but not nonneutralizing antibodies in the acute phase2016
- Author(s)
  Yamamoto H, Iseda S, Nakane T, Nomura T, Takahashi N, Seki S, Nakamura M, Ishii H and Matano T
- Journal Title
  
  AIDS
  
  Volume: 30(15) Issue: 15 Pages: 2391-4
- DOI
  10.1097/qad.0000000000001221
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K19119
[Journal Article] Broadening of Virus-Specific CD8+ T-Cell Responses Is Indicative of Residual Viral Replication in Aviremic SIV Controllers2015
- Author(s)
  Takushi Nomura, Hiroyuki Yamamoto, Hiroshi Ishii, Hirofumi Akari, Taeko K. Naruse, Akinori Kimura, Tetsuro Matano
- Journal Title
  
  PLOS Pathogens
  
  Volume: 11 Issue: 11 Pages: e1005247-e1005247
- DOI
  10.1371/journal.ppat.1005247
- NAID
  120005763387
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-15K19119, KAKENHI-PUBLICLY-15H01271, KAKENHI-PROJECT-15H04737, KAKENHI-PROJECT-25670218
[Journal Article] Identification of SIV Nef CD8(+) T cell epitopes restricted by a MHC class I haplotype associated with lower viral loads in a macaque AIDS model.2014
- Author(s)
  Nomura T, Yamamoto H, Takahashi N, Naruse TK, Kimura A, Matano T.
- Journal Title
  
  Biochem Biophys Res Commun.
  
  Volume: 450 Issue: 2 Pages: 942-947
- DOI
  10.1016/j.bbrc.2014.06.072
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24590398, KAKENHI-PUBLICLY-25115520, KAKENHI-PROJECT-25860348, KAKENHI-PROJECT-25893294
[Journal Article] Control of SIV replication by vaccine-induced Gag- and Vif-specific CD8+ T cells2014
- Author(s)
  Nami Iwamoto, Naofumi Takahashi, Sayuri Seki, Takushi Nomura, Hiroyuki Yamamoto, Makoto Inoue, Tsugumine Shu, Taeko K. Naruse, Akinori Kimura, and Tetsuro Matano
- Journal Title
  
  J. Virol.
  
  Volume: 88 Issue: 1 Pages: 425-433
- DOI
  10.1128/jvi.02634-13
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23390115, KAKENHI-PROJECT-24590398, KAKENHI-PUBLICLY-25115520, KAKENHI-PROJECT-25860348, KAKENHI-PROJECT-25893294
[Journal Article] Vaccine-induced CD107a+ CD4+ T cells are resistant to depletion following AIDS virus infection2014
- Author(s)
  Kazutaka Terahara, Hiroshi Ishii, Takushi Nomura, Naofumi Takahashi, Akiko Takeda, Teiichiro Shiino, Yasuko Tsunetsugu-Yokota, and Tetsuro Matano
- Journal Title
  
  J. Virol.
  
  Volume: 88 Issue: 24 Pages: 14232-14240
- DOI
  10.1128/jvi.02032-14
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PUBLICLY-25115520, KAKENHI-PROJECT-25893294
[Journal Article] Limited impact of passive non-neutralizing antibody immunization in acute SIV infection on viremia control in rhesus macaques2013
- Author(s)
  Taku Nakane, Takushi Nomura, Shoi Shi, Midori Nakamura, Taeko K. Naruse, Akinori Kimura, Tetsuro Matano, and Hiroyuki Yamamoto
- Journal Title
  
  PLoS ONE
  
  Volume: 8 Issue: 9 Pages: e73453-e73453
- DOI
  10.1371/journal.pone.0073453
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23390115, KAKENHI-PROJECT-24590398, KAKENHI-PUBLICLY-25115520, KAKENHI-PROJECT-25860348, KAKENHI-PROJECT-25893294
[Presentation] SARS-CoV-2感染マウスモデルを用いた年齢依存的な病態に関連するT細胞動態の解析2023
- Author(s)
  野村拓志
- Organizer
  第70回日本ウイルス学会学術集会
- Data Source
  KAKENHI-PROJECT-21K07061
[Presentation] The development of a novel animal model for analyzing immune responses in tissues which contributes to eliminating the HIV reservoir.2023
- Author(s)
  Takushi Nomura
- Organizer
  第37回日本エイズ学会学術集会・総会
- Invited
- Data Source
  KAKENHI-PROJECT-21K07061
[Presentation] Selection of multiple viral CD8+ T-cell escape mutations associated with a protective MHC-I haplotype in persistent SIV infection2021
- Author(s)
  Ntim Nana Afia Asante, Takushi Nomura, Hiroshi Ishii, and Tetsuro Matano
- Organizer
  The 22nd Kumamoto AIDS Seminar
- Data Source
  KAKENHI-PROJECT-21K07061
[Presentation] サルエイズモデルにおける組織リザーバー解析2020
- Author(s)
  野村拓志
- Organizer
  第34回日本エイズ学会学術集会
- Invited
- Data Source
  KAKENHI-PROJECT-19K16679
[Presentation] Efficacy of vaccine-induced crossreactive CD8+ T cells targeting a Gag epitope against SIVmac239 challenge2019
- Author(s)
  Takushi Nomura
- Organizer
  The 67th Annual Meeting of the Japanese Society for Virology
- Data Source
  KAKENHI-PROJECT-19K16679
[Presentation] Contribution of vaccine-induced mutant epitope-crossreactive CD8+ T cells to stable control of SIVmac239 replication2019
- Author(s)
  Takushi Nomura
- Organizer
  The 37th Annual Symposium on Nonhuman Primate Models for AIDS
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K16679
[Presentation] ワクチン誘導Gag241-249エピトープ特異的 CD8陽性T細胞の交差反応性が SIV感染に与える影響の解析2019
- Author(s)
  野村拓志
- Organizer
  第33回日本エイズ学会学術集会
- Data Source
  KAKENHI-PROJECT-19K16679
[Presentation] Analysis of wild-type and mutant epitope-specific CD8+ T cell responses in SIV controllers.2017
- Author(s)
  Takushi Nomura, Hiroshi Ishii, Sayuri Seki, Hiroyuki Yamamoto, Kazutaka Terahara, Tomoyuki Miura and Tetsuro Matano
- Organizer
  65th Annual Meeting of the Japanese Society for Virology
- Data Source
  KAKENHI-PROJECT-15K19119
[Presentation] SIV複製制御個体におけるSIV野生型/変異型エピトープ特異的CTL誘導動態の解析2017
- Author(s)
  野村拓志、石井洋、関紗由里、山本浩之、寺原和孝、三浦智行、俣野哲朗
- Organizer
  第31回日本エイズ学会学術集会
- Data Source
  KAKENHI-PROJECT-15K19119
[Presentation] Induction of mutant epitope-specific CD8+ T cells is an indicator of the beginning of viral control failure in SIV controllers.2017
- Author(s)
  Takushi Nomura, Hiroshi Ishii, Sayuri Seki, Hiroyuki Yamamoto, Kazutaka Terahara, Tomoyuki Miura and Tetsuro Matano
- Organizer
  35th Annual symposium on nonhuman primate models for AIDS
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K19119
[Presentation] Analysis of proviral genome sequences in individual cell subsets in SIV-infected rhesus macaques2016
- Author(s)
  Takushi Nomura, Hiroyuki Yamamoto, Kazutaka Terahara, Sayuri Seki and Tetsuro Matano
- Organizer
  34th Annual Symposium on Nonhuman Primate
- Place of Presentation
  New Orleans, USA
- Year and Date
  2016-10-11
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K19119
[Presentation] Proviral genome sequences in lymph nodes and bone marrows in SIV-infected rhesus macaques2016
- Author(s)
  Takushi Nomura, Hiroyuki Yamamoto, Kazutaka Terahara, Sayuri Seki and Tetsuro Matano
- Organizer
  The 64th Annual Meeting of the Japanese Society for Virology
- Place of Presentation
  Sapporo, Japan
- Year and Date
  2016-10-23
- Data Source
  KAKENHI-PROJECT-15K19119
[Presentation] Analysis of proviral genome sequences in multiple cell subsets in SIV-infected rhesus macaques2016
- Author(s)
  Takushi Nomura, Hiroyuki Yamamoto, Kazutaka Terahara, Sayuri Seki and Tetsuro Matano
- Organizer
  17th Kumamoto AIDS seminar
- Place of Presentation
  Kumamoto, Japan
- Year and Date
  2016-10-31
- Data Source
  KAKENHI-PROJECT-15K19119
[Presentation] Effects of IL-7 and IL-15 administration on SIV controllers2015
- Author(s)
  Takushi Nomura, Hiroyuki Yamamoto, and Tetsuro Matano
- Organizer
  The 63rd Annual Meeting of the Japanese Society for Virology
- Place of Presentation
  福岡国際会議場
- Year and Date
  2015-11-22
- Data Source
  KAKENHI-PROJECT-15K19119
[Presentation] Association between broadening of CD8+ T-cell targets and accumulation of proviral escape mutations in SIV controllers2014
- Author(s)
  Takushi Nomura, Hiroyuki Yamamoto and Tetsuro Matano
- Organizer
  Keystone simposia "HIV Vaccines: Adaptive Immunity and Beyond (X3)"
- Place of Presentation
  Banff, Canada
- Data Source
  KAKENHI-PROJECT-25893294
[Presentation] SIV感染制御群における制御維持へのVifおよびNef特異的細胞傷害性Tリンパ球反応の関与に関する研究2013
- Author(s)
  野村拓志、俣野哲朗
- Organizer
  第61回ウイルス学会学術集会
- Place of Presentation
  神戸
- Data Source
  KAKENHI-PROJECT-25893294
[Presentation] Broadening of CD8+ T-cell targets precedes accumulation of proviral escape mutations in SIV controllers
- Author(s)
  Takushi Nomura, Hiroyuki Yamamoto and Tetsuro Matano
- Organizer
  The 15th KUMAMOTO AIDS Seminar
- Place of Presentation
  Aso, Kumamoto
- Year and Date
  2014-10-01 – 2014-10-03
- Data Source
  KAKENHI-PROJECT-25893294
[Presentation] Lasting SIV control by multiple Gag, Vif, and Nef epitope-specific CD8+ T cells
- Author(s)
  Takushi Nomura, Hiroyuki Yamamoto and Tetsuro Matano
- Organizer
  32ND ANNUAL SYMPOSIUM ON NONHUMAN PRIMATE MODELS FOR AIDS
- Place of Presentation
  Portland, Oregon, USA
- Year and Date
  2014-11-11 – 2014-11-14
- Data Source
  KAKENHI-PROJECT-25893294

1. 上野貴将 (10322314)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
2. BARABONA GODFREY (40906674)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
3. 小野昌弘 (60447951)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
4. 佐藤賢文 (70402807)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
5. YAMAMOTO Hiroyuki

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
6. NARUSE Taeko

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
7. 木村彰方

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
8. 俣野哲朗

# of Collaborated Projects: 0 results

# of Collaborated Products: 9 results

Nomura Takushi 野村 拓志

NOMURA Takushi 野村 拓志

Research Projects

Research Products

Co-Researchers

T細胞免疫老化によるSARS-CoV-2重症化機序の動物モデルを用いた解明Principal Investigator

Principal Investigator

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Research Category

Review Section

Research Institution

Impact of cross-reactive immunity to pre-existing infections on COVID-19 pathogenesis in East Africa

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Investigation for potential CTL epitopes spanning various coronavirues aiming for universal vaccine development

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Analysis of CD8+T-cell dominance in SIV progressorPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Analysis of cross-reactivity of dominant SIV-specific CD8+T cells associate with viral control in SIV infected Burmese rhesus macaque.Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Analysis of latent reservoir in SIV controllesPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Mechanism analysis of lasting of AIDS virus control with SIV controllers.Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Book] 実験医学 別冊 2016 Vol.34 No.132016

Author(s)

Total Pages

Publisher

Data Source

[Journal Article] HTLV-1 Proliferation after CD8 + Cell Depletion by Monoclonal Anti-CD8 Antibody Administration in Latently HTLV-1-Infected Cynomolgus Macaques2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Env-independent protection of intrarectal SIV challenge by vaccine induction of Gag/Vif-specific CD8+ T cells but not CD4+ T cells2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Hierarchy of multiple viral CD8+ T-cell epitope mutations in sequential selection in simian immunodeficiency infection2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Late-phase dominance of a single epitope-specific CD8+ T-cell response in passive neutralizing antibody-infused simian immunodeficiency virus controllers2021

Author(s)

Journal Title

DOI

Data Source

[Journal Article] A Novel Immunogen Selectively Eliciting CD8(+) T Cells but Not CD4(+) T Cells Targeting Immunodeficiency Virus Antigens.2020

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DOI

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[Journal Article] Therapeutic vaccine-mediated Gag-specific CD8+ T-cell induction under anti-retroviral therapy augments anti-virus efficacy of CD8+ cells in simian immunodeficiency virus-infected macaques2020

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Nomura Takushi 野村拓志

NOMURA Takushi 野村拓志

[Book] 実験医学　別冊　2016 Vol.34 No.132016