Shibata Tomonori 柴田知範

Researcher Number	80711960
Other IDs
Affiliation (Current)	2022: 大阪大学, 産業科学研究所, 助教
Affiliation (based on the past Project Information) *help	2017 – 2021: 大阪大学, 産業科学研究所, 助教 2016: 大阪大学, 産業科学研究所, 特任助教(常勤) 2015: 大阪大学, 産業科学研究所, 特任助教 2014: 京都大学, iPS細胞研究所, 研究員
Review Section/Research Field	Principal Investigator Bio-related chemistry / Chemical biology / Basic Section 37030:Chemical biology-related / Medium-sized Section 37:Biomolecular chemistry and related fields
Keywords	Principal Investigator 脊髄小脳変性症31型 / RNA結合性低分子 / リピートRNA / RNA / タンパク質 / 核酸ナノテクノロジー / RNAナノテクノロジー / RNA-タンパク質複合体 / 核酸ナノ構造 / RNAナノ構造 … More

CAGリピート結合分子の経鼻投与後における脳内動態解明及びリピート短縮効果の検証Principal Investigator
- Principal Investigator
  
  柴田知範
- Project Period (FY)
  2021 – 2022
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Review Section
  
  Medium-sized Section 37:Biomolecular chemistry and related fields
- Research Institution
  Osaka University
脊髄小脳変性症31型を標的とする低分子の作用機序解明と毒性リピートRNA機能抑制Principal Investigator
- Principal Investigator
  
  柴田知範
- Project Period (FY)
  2020 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 37030:Chemical biology-related
- Research Institution
  Osaka University
Elucidation of action mechanism of repeat RNA-binding small molecules that improve disease phenotype in spinocerebellar ataxia type 31Principal Investigator
- Principal Investigator
  
  Shibata Tomonori
- Project Period (FY)
  2017 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Chemical biology
- Research Institution
  Osaka University
Functional molecular robot using RNA/RNP nanostructuresPrincipal Investigator
- Principal Investigator
  
  Shibata Tomonori
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Bio-related chemistry
- Research Institution
  Osaka University
  Kyoto University

All 2021 2019 2018 2015 Other

All Journal Article Presentation Book Patent

[Book] Methods in Molecular Biology 1316 (Chapter 14)2015
- Author(s)
  Tomonori Shibata, Yuki Suzuki, Hiroshi Sugiyama, Masayuki Endo, and Hirohide Saito
- Publisher
  Human press
- Data Source
  KAKENHI-PROJECT-26810089
[Book] Methods Mol Biol.2015
- Author(s)
  Shibata T, Suzuki Y, Sugiyama H, Endo M, Saito H
- Publisher
  Humana Press
- Data Source
  KAKENHI-PROJECT-26810089
[Journal Article] Small molecule targeting r(UGGAA)n disrupts RNA foci and alleviates disease phenotype in Drosophila model2021
- Author(s)
  Shibata Tomonori、Nagano Konami、Ueyama Morio、Ninomiya Kensuke、Hirose Tetsuro、Nagai Yoshitaka、Ishikawa Kinya、Kawai Gota、Nakatani Kazuhiko
- Journal Title
  
  Nature Communications
  
  Volume: 12 Pages: 0000-0000
- DOI
  10.1038/s41467-020-20487-4
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K06478, KAKENHI-PROJECT-19K22254, KAKENHI-PROJECT-19H00924, KAKENHI-PROJECT-17K01962
[Patent] 脊髄小脳変性症31型抑制剤2018
- Inventor(s)
  中谷和彦、柴田知範、永井義隆、上山盛夫
- Industrial Property Rights Holder
  中谷和彦、柴田知範、永井義隆、上山盛夫
- Industrial Property Rights Type
  実用新案
- Filing Date
  2018
- Acquisition Date
  2018
- Data Source
  KAKENHI-PROJECT-17K01962
[Presentation] 脊髄小脳変性症 31 型を標的とする RNA 結合性低分子2019
- Author(s)
  柴田知範、長野来南、上山盛夫、永井義隆、石川欽也、河合剛太、中谷和彦
- Organizer
  日本ケミカルバイオロジー学会第14回年会
- Data Source
  KAKENHI-PROJECT-17K01962
[Presentation] RNA binding small molecule that mitigates disease phenotype in spinocerebellar ataxia type 312019
- Author(s)
  Tomonori Shibata, Konami Nagano, Morio Ueyama, Yoshitaka Nagai, Kinya Ishikawa, Gota Kawai, Kazuhiko Nakatani
- Organizer
  The Commemorative International Symposium of the Japan Society of Nucleic Acids Chemistry (CISNAC 2019)
- Data Source
  KAKENHI-PROJECT-17K01962
[Presentation] A small molecule that alleviates RNA-mediated neurodegeneration in spinocerebellar ataxia type 312018
- Author(s)
  Tomonori Shibata
- Organizer
  Aptamer in Boulder
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K01962
[Presentation] Synthetic RNA-protein nano machines that function in vitro and in live cell2015
- Author(s)
  ○Shibata T, Suzuki Y, Sugiyama H, Endo M, Saito H
- Organizer
  ISNAC20
- Place of Presentation
  イーグレ姫路 (兵庫県　姫路市)
- Year and Date
  2015-09-23
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26810089
[Presentation] タンパク質応答性RNAナノマシン2015
- Author(s)
  ○柴田知範、鈴木勇輝、杉山弘、遠藤政幸、齊藤博英
- Organizer
  日本RNA学会年会
- Place of Presentation
  ホテルライフォート札幌 (北海道　札幌市)
- Year and Date
  2015-07-15
- Data Source
  KAKENHI-PROJECT-26810089
[Presentation] A RNA-protein-based nanomachine for controlling functional RNAs
- Author(s)
  Tomonori Shibata, Yuki Suzuki, Hiroshi Sugiyama, Masayuki Endo, Hirohide Saito
- Organizer
  The 41st International Symposium on Nucleic Acids Chemistry 2014
- Place of Presentation
  北九州
- Year and Date
  2014-11-05 – 2014-11-07
- Data Source
  KAKENHI-PROJECT-26810089
[Presentation] Photo-regulation of RNA-protein-based nanostructures
- Author(s)
  Tomonori Shibata, Kenzo Fujimoto, Yuki Suzuki, Hiroshi Sugiyama, Masayuki Endo, Masahiro Takinoue, Hirohide Saito
- Organizer
  20th International Conference on DNA computing and Molecular Programming
- Place of Presentation
  京都
- Year and Date
  2014-09-22 – 2014-09-26
- Data Source
  KAKENHI-PROJECT-26810089

1. 二宮賢介

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
2. 中谷和彦

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Shibata Tomonori 柴田 知範

Research Projects

Research Products

Co-Researchers

CAGリピート結合分子の経鼻投与後における脳内動態解明及びリピート短縮効果の検証Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

脊髄小脳変性症31型を標的とする低分子の作用機序解明と毒性リピートRNA機能抑制Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Elucidation of action mechanism of repeat RNA-binding small molecules that improve disease phenotype in spinocerebellar ataxia type 31Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Functional molecular robot using RNA/RNP nanostructuresPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Book] Methods in Molecular Biology 1316 (Chapter 14)2015

Author(s)

Publisher

Data Source

[Book] Methods Mol Biol.2015

Author(s)

Publisher

Data Source

[Journal Article] Small molecule targeting r(UGGAA)n disrupts RNA foci and alleviates disease phenotype in Drosophila model2021

Author(s)

Journal Title

DOI

Data Source

[Patent] 脊髄小脳変性症31型抑制剤2018

Inventor(s)

Industrial Property Rights Holder

Industrial Property Rights Type

Filing Date

Acquisition Date

Data Source

[Presentation] 脊髄小脳変性症 31 型を標的とする RNA 結合性低分子2019

Author(s)

Organizer

Data Source

[Presentation] RNA binding small molecule that mitigates disease phenotype in spinocerebellar ataxia type 312019

Author(s)

Organizer

Data Source

[Presentation] A small molecule that alleviates RNA-mediated neurodegeneration in spinocerebellar ataxia type 312018

Author(s)

Organizer

Data Source

[Presentation] Synthetic RNA-protein nano machines that function in vitro and in live cell2015

Author(s)

Organizer

Place of Presentation

Year and Date

Data Source

[Presentation] タンパク質応答性RNAナノマシン2015

Author(s)

Organizer

Place of Presentation

Year and Date

Data Source

[Presentation] A RNA-protein-based nanomachine for controlling functional RNAs

Author(s)

Organizer

Place of Presentation

Year and Date

Data Source

[Presentation] Photo-regulation of RNA-protein-based nanostructures

Author(s)

Shibata Tomonori 柴田知範