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Fujii Hajime  藤井 哉

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藤井 哉  フジイ ハジメ

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Researcher Number 80717546
Other IDs
Affiliation (Current) 2025: 東京大学, 大学院医学系研究科(医学部), 講師
Affiliation (based on the past Project Information) *help 2023: 東京大学, 大学院医学系研究科(医学部), 講師
2016 – 2018: 東京大学, 大学院医学系研究科(医学部), 助教
2014 – 2015: 東京大学, 医学(系)研究科(研究院), 助教
Review Section/Research Field
Principal Investigator
Basic Section 48020:Physiology-related / Basic / Social brain science / Neurochemistry/Neuropharmacology
Keywords
Principal Investigator
蛍光イメージング / Ca2+シグナリング / イメージング / 神経科学 / シグナル伝達 / シナプス可塑性 / Ca2+シグナル伝達 / リン酸化シグナル伝達 / リン酸化シグナル / カルシウムシグナル … More / 神経機能 / 光操作 / 神経可塑性 / 分子生物学 / 顕微鏡 / 蛍光プローブ / 生化学 / シナプス / Ca2+シグナル Less
  • Research Projects

    (3 results)
  • Research Products

    (36 results)
  • Co-Researchers

    (2 People)
  •  空間認知を担うCa2+依存的リン酸化・脱リン酸化シグナル規則の解明Principal Investigator

    • Principal Investigator
      藤井 哉
    • Project Period (FY)
      2023 – 2025
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 48020:Physiology-related
    • Research Institution
      The University of Tokyo
  •  Analysis of neural functions by optical manipulation of calcineurinPrincipal Investigator

    • Principal Investigator
      Fujii Hajime
    • Project Period (FY)
      2017 – 2018
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      Basic / Social brain science
    • Research Institution
      The University of Tokyo
  •  Analysis of biochemical computation and dynamics in neurons.Principal Investigator

    • Principal Investigator
      Fujii Hajime
    • Project Period (FY)
      2014 – 2016
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      Neurochemistry/Neuropharmacology
    • Research Institution
      The University of Tokyo

All 2018 2017 2016 2015 2014 Other

All Journal Article Presentation

  • [Journal Article] A Critical Neurodevelopmental Role for L-Type Voltage-Gated Calcium Channels in Neurite Extension and Radial Migration2018

    • Author(s)
      Kamijo Satoshi、Ishii Yuichiro、Horigane Shin-ichiro、Suzuki Kanzo、Ohkura Masamichi、Nakai Junichi、Fujii Hajime、Takemoto-Kimura Sayaka、Bito Haruhiko
    • Journal Title

      The Journal of Neuroscience

      Volume: 38 Issue: 24 Pages: 5551-5566

    • DOI

      10.1523/jneurosci.2357-17.2018

    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-16H06536, KAKENHI-PLANNED-17H06312, KAKENHI-PROJECT-17K13270, KAKENHI-PROJECT-15H05723
  • [Journal Article] Calmodulin kinases: essential regulators in health and disease.2017

    • Author(s)
      Takemoto-Kimura S, Suzuki K, Horigane SI, Kamijo S, Inoue M, Sakamoto M, Fujii H, Bito H.
    • Journal Title

      J Neurochem.

      Volume: - Issue: 6 Pages: 808-818

    • DOI

      10.1111/jnc.14020

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PUBLICLY-16H01268, KAKENHI-PUBLICLY-16H01328, KAKENHI-PROJECT-15H02358, KAKENHI-PROJECT-16H06728, KAKENHI-PROJECT-16K13105, KAKENHI-PROJECT-15K18372, KAKENHI-PROJECT-26830043, KAKENHI-PROJECT-16H06276, KAKENHI-PROJECT-15K14345, KAKENHI-PROJECT-16H04670
  • [Journal Article] Facilitation of axon outgrowth via a Wnt5a-CaMKK-CaMKIα pathway during neuronal polarization.2016

    • Author(s)
      Horigane S, Ageta-Ishihara N, Kamijo S, Fujii H, Okamura M, Kinoshita M, Takemoto-Kimura S, Bito H
    • Journal Title

      Mol Brain.

      Volume: 9 Issue: 1 Pages: 8-8

    • DOI

      10.1186/s13041-016-0189-3

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26830043, KAKENHI-PUBLICLY-26117503, KAKENHI-PROJECT-15H02358, KAKENHI-PROJECT-26440095, KAKENHI-PROJECT-15K14345
  • [Journal Article] Rational design of a high-affinity, fast, red calcium indicator R-CaMP2.2015

    • Author(s)
      Inoue M, Takeuchi A, Horigane S, Ohkura M, Gengyo-Ando K, Fujii H, Kamijo S, Takemoto-Kimura S, Kano M, Nakai J, Kitamura K, Bito H
    • Journal Title

      Nat Methods

      Volume: 12 Issue: 1 Pages: 64-70

    • DOI

      10.1038/nmeth.3185

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-12J01373, KAKENHI-PROJECT-221S0003, KAKENHI-PROJECT-23680040, KAKENHI-PROJECT-25000015, KAKENHI-PUBLICLY-25111703, KAKENHI-PUBLICLY-25113705, KAKENHI-PUBLICLY-25115705, KAKENHI-PUBLICLY-25116504, KAKENHI-PROJECT-25290003, KAKENHI-PROJECT-25560432, KAKENHI-PROJECT-25640004, KAKENHI-PUBLICLY-26115504, KAKENHI-PUBLICLY-26115507, KAKENHI-PUBLICLY-26117503, KAKENHI-PROJECT-26282217, KAKENHI-PROJECT-26560456, KAKENHI-PROJECT-26640002, KAKENHI-PROJECT-26830043, KAKENHI-PROJECT-15K14308
  • [Presentation] Multiplex imaging of neuronal Ca2+-mediated signal transduction2018

    • Author(s)
      Hajime Fujii, Masatoshi Inoue, Haruhiko Bito
    • Organizer
      Janelia Conference Fluorescent Proteins and Biological Sensors VI
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17K13270
  • [Presentation] Development and imaging of new color indicators for Ca2+ signaling in living neurons2018

    • Author(s)
      Fujii H
    • Organizer
      UK-Japan Neuroscience Symposium, Royal Society, London
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17K13270
  • [Presentation] Deciphering Ca2+-dependent signaling pathways underlying cognitive processes.2018

    • Author(s)
      Bito H. Kim R, Inoue M, Inokuchi K, Yokoyama T, Sakai K, Miyazawa Y, Ishii Y, Okamura M, Gammon N, Kobari S, Kondo Y, Sakamoto M, Fujii H.
    • Organizer
      China-Japan Joint Symposium "From Neuronal Circuits to Behavior", 95th Annual Meeting of the Physiological Society of Japan
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17K13270
  • [Presentation] Imaging of multiple Ca2+ signaling components in living neurons and synapses2018

    • Author(s)
      藤井 哉、井上 昌俊、尾藤 晴彦
    • Organizer
      第41回日本神経科学大会
    • Invited
    • Data Source
      KAKENHI-PROJECT-17K13270
  • [Presentation] Rational engineering of XCaMPs, a multicolor GECI suite for In vivo imaging of brain circuit dynamics.2017

    • Author(s)
      Inoue M, Takeuchi A, Manita S, Horigane S, Kawakami R, Yamaguchi K, Sakamoto M, Yokoyama H, Kim R, Takemoto-Kimura S, Abe M, Yokoyama T, Quirin S, Ramakrishnan C, Sakimura K, Nemoto T, Kano M, Fujii H, Deisseroth K, Kitamura K, Bito H
    • Organizer
      The 48th Annual Meeting of the Society for Neuroscience, Washington Convention Center, Washington DC, USA.
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17K13270
  • [Presentation] Ca2+シグナル伝達のプローブ開発と多重イメージング2017

    • Author(s)
      藤井哉、井上昌俊、尾藤晴彦
    • Organizer
      第11回NIBBバイオイメージングフォーラム
    • Place of Presentation
      岡崎
    • Year and Date
      2017-02-14
    • Invited
    • Data Source
      KAKENHI-PROJECT-26830043
  • [Presentation] Novel functions of Ca2+-dependent phosphorylation cascades in the period of neuronal circuit formation.2017

    • Author(s)
      Takemoto-Kimura S, Horigane S, Suzuki K, Kamijo S, Fujii H, Bito H.
    • Organizer
      CONBIO2017 Joint Annual Meeting of the Japan Biochemistry Society and the Molecular Biology Society of Japan
    • Data Source
      KAKENHI-PROJECT-17K13270
  • [Presentation] Imaging long-term potentiation of surface glutamate receptors at single synapses2017

    • Author(s)
      Ishii Y, Okuno H, Fujii H, Bito H.
    • Organizer
      第94回日本生理学会大会
    • Place of Presentation
      浜松
    • Invited
    • Data Source
      KAKENHI-PROJECT-26830043
  • [Presentation] Development and imaging of new color indicators for Ca2+ signaling in living neurons.2017

    • Author(s)
      Fujii H, Inoue M, Bito H
    • Organizer
      The 40th Annual Meeting of the Japan Neuroscience Society, Makuhari, Japan.
    • Data Source
      KAKENHI-PROJECT-17K13270
  • [Presentation] Calcium-dependent phosphorylation signaling in emotional and social limbic circuit2016

    • Author(s)
      Takemoto-Kimura S, Suzuki K, Endo T, Kim R, Koyama H, Horigane S, Fujii H, Bito H.
    • Organizer
      第39回日本神経科学大会
    • Place of Presentation
      横浜
    • Year and Date
      2016-07-20
    • Invited
    • Data Source
      KAKENHI-PROJECT-26830043
  • [Presentation] Development and imaging of new color indicators for Ca2+ signaling in living neurons.2016

    • Author(s)
      Fujii H, Inoue M, Bito H
    • Organizer
      第39回日本神経科学大会
    • Place of Presentation
      横浜
    • Year and Date
      2016-07-20
    • Invited
    • Data Source
      KAKENHI-PROJECT-26830043
  • [Presentation] Rational engineering of sensors for hierarchical and orthogonal Ca2+ signaling.2016

    • Author(s)
      Fujii H, Inoue M, Bito H.
    • Organizer
      The 46th Annual Meeting of the Society for Neuroscience
    • Place of Presentation
      San Diego, USA
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26830043
  • [Presentation] Excitation-morphogenesis coupling during corticogenesis: a critical role for L-type voltage-gated calcium channel-driven spontaneous calcium elevations in neurite extension and radial migration2016

    • Author(s)
      Kamijo S, Suzuki K, Horigane S-I, Fujii H, Takemoto-Kimura S, Bito H
    • Organizer
      The 46th Annual Meeting of the Society for Neuroscience
    • Place of Presentation
      San Diego, USA
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26830043
  • [Presentation] Ca2+シグナリングの可視化プローブの開発と多重イメージング2016

    • Author(s)
      藤井哉、井上昌俊、尾藤晴彦
    • Organizer
      生理学研究所 研究会「シナプス伝達の細胞分子調節機構」
    • Place of Presentation
      岡崎
    • Year and Date
      2016-11-21
    • Invited
    • Data Source
      KAKENHI-PROJECT-26830043
  • [Presentation] Nonlinear Decoding and Asymmetric Representation of Neuronal Input Information by CaMKIIα and Calcineurin.2016

    • Author(s)
      Fujii H, Inoue M, Bito H
    • Organizer
      第54回日本生物物理学会年会シンポジウム
    • Place of Presentation
      つくば
    • Year and Date
      2016-11-25
    • Invited
    • Data Source
      KAKENHI-PROJECT-26830043
  • [Presentation] 扁桃体神経回路におけるカルシウム依存的リン酸化経路と情動行動2016

    • Author(s)
      竹本さやか、遠藤俊裕、金亮、鈴木敢三、藤井哉、尾藤晴彦
    • Organizer
      第46回日本神経精神薬理学会
    • Place of Presentation
      ソウル
    • Invited
    • Data Source
      KAKENHI-PROJECT-26830043
  • [Presentation] 恐怖記憶を制御する活動依存的神経細胞集団2016

    • Author(s)
      尾藤晴彦、金亮、井上昌俊、坂本雅行、藤井哉
    • Organizer
      第59回日本神経化学会、第38回日本生物学的精神医学会合同年会
    • Place of Presentation
      福岡
    • Year and Date
      2016-09-08
    • Invited
    • Data Source
      KAKENHI-PROJECT-26830043
  • [Presentation] Facilitation of axon outgrowth via a Wnt5a-CaMKK-CaMKIα pathway.2016

    • Author(s)
      Horigane S, Ageta-Ishihara N, Kamijyo S, Fujii H, Okamura M, Kinoshita M, Takemoto-Kimura S, Bito H.
    • Organizer
      第16回東京大学生命科学シンポジウム
    • Place of Presentation
      東京
    • Data Source
      KAKENHI-PROJECT-26830043
  • [Presentation] Facilitation of axon outgrowth via a Wnt5a-CaMKK-CaMKIα pathway.2016

    • Author(s)
      Horigane S, Ageta-Ishihara N, Kamijyo S, Fujii H, Okamura M, Kinoshita M, Takemoto-Kimura S, Bito H
    • Organizer
      第39回日本神経科学大会
    • Place of Presentation
      横浜
    • Year and Date
      2016-07-20
    • Data Source
      KAKENHI-PROJECT-26830043
  • [Presentation] カルシウムシグナリングと脳高次機能制御2016

    • Author(s)
      金亮, 井上昌俊, 野中美応, 川島尚之, 奧野浩行, 竹本-木村さやか, 坂本雅行, 藤井哉, 尾藤晴彦
    • Organizer
      私立大学戦略的研究基盤形成支援事業 中間報告会シンポジウム「次世代の包括的緩和医療を支える最先端基礎/臨床融合型研究の基盤形成」
    • Place of Presentation
      東京
    • Invited
    • Data Source
      KAKENHI-PROJECT-26830043
  • [Presentation] Rational design of ultrafast, high-affinity calcium indicators for monitoring neuronal activity2016

    • Author(s)
      Inoue M, Takeuchi A, HoriganeS, Fujii H, Kamijo S, Takemoto-Kimura S, Ohkura M, Gengyo-Ando K, Kano M, Nakai J, Kitamura K, Bito H.
    • Organizer
      The 7th International Neural Microcircuit Conference
    • Place of Presentation
      Okazaki
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26830043
  • [Presentation] Rational engineering of sensors for hierarchical and orthogonal Ca2+ signaling2016

    • Author(s)
      藤井哉、井上昌俊、尾藤晴彦
    • Organizer
      第8回イメージング若手の会「光塾」
    • Place of Presentation
      横浜
    • Year and Date
      2016-12-17
    • Data Source
      KAKENHI-PROJECT-26830043
  • [Presentation] Rational design of ultrafast, high-affinity red calcium indicator for monitoring neuronal activity.2015

    • Author(s)
      Inoue M, Takeuchi A, Horigane S, Fujii H, Kamijo S, Takemoto-Kimura S, Ohkura M, Gengyo-Ando K, Kano M, Nakai J, Kitamura K, Bito H
    • Organizer
      The 45th Annual Meeting of the Society for Neuroscience
    • Place of Presentation
      Chicago, USA
    • Year and Date
      2015-10-18
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26830043
  • [Presentation] Nonlinear Decoding and Asymmetric Representation of Neuronal Input Information by CaMKIIα and Calcineurin.2015

    • Author(s)
      Fujii H, Inoue M, Okuno H, Sano Y, Takemoto-Kimura S, Kitamura K, Kano M, Bito H
    • Organizer
      第7回「光塾」
    • Place of Presentation
      広島大学 東広島キャンパス
    • Year and Date
      2015-09-05
    • Data Source
      KAKENHI-PROJECT-26830043
  • [Presentation] Rational design of a novel high-affinity, ultrafast, red calcium indicator R-CaMP22015

    • Author(s)
      Inoue M, Takeuchi A, Horigane S, Ohkura M, Gengyo-Ando K, Fujii H, Kamijo S, Takemoto-Kimura S, Kano M, Nakai J, Kitamura K, Bito H
    • Organizer
      第92回日本生理学会大会
    • Place of Presentation
      神戸
    • Year and Date
      2015-03-21
    • Data Source
      KAKENHI-PROJECT-26830043
  • [Presentation] Rational design of a high-affinity, fast, red calcium indicator R-CaMP22015

    • Author(s)
      Inoue M, Takeuchi A, Horigane S, Ohkura M, Gengyo-Ando K, Fujii H, Kamijo S, Takemoto-Kimura S, Kano M, Nakai J, Kitamura K, Bito H
    • Organizer
      第88回日本薬理学会年会
    • Place of Presentation
      名古屋
    • Year and Date
      2015-03-18
    • Data Source
      KAKENHI-PROJECT-26830043
  • [Presentation] Rational design of a novel high-affinity, ultrafast, red calcium indicator R-CaMP22014

    • Author(s)
      Inoue M, Takeuchi A, Horigane S, Ohkura M, Gengyo-Ando K, Fujii H, Kamijo S, Takemoto-Kimura S, Kano M, Nakai J, Kitamura K, Bito H
    • Organizer
      2014年度包括脳ネットワーク冬のシンポジウム
    • Place of Presentation
      東京
    • Year and Date
      2014-12-11
    • Data Source
      KAKENHI-PROJECT-26830043
  • [Presentation] Signaling from synapse to the nucleus and imaging of active neuronal ensembles2014

    • Author(s)
      Bito H, Inoue M, Nonaka M, Yagishita-Kyo N, Kawashima T, Suzuki K, Ishii Y, Fujii H, Endo T, Goto M, Koyama H, Takemoto-Kimura S, Kim R
    • Organizer
      第37回日本神経科学大会
    • Place of Presentation
      横浜
    • Year and Date
      2014-09-11
    • Invited
    • Data Source
      KAKENHI-PROJECT-26830043
  • [Presentation] Spontaneous L-type calcium channel activity regulates local calcium signaling in the neurites of developing cortical neurons.2014

    • Author(s)
      Kamijo S, Suzuki K, Horigae H, Fujii H, Takemoto-Kimura S, Bito H
    • Organizer
      The 44th Annual Meeting of the Society for Neuroscience
    • Place of Presentation
      Washington DC, USA
    • Year and Date
      2014-11-19
    • Data Source
      KAKENHI-PROJECT-26830043
  • [Presentation] Nonlinear decoding and asymmetric representation of neuronal input information by CaMKIIalpha and calcineurin2014

    • Author(s)
      Fujii H, Inoue M, Okuno H, Sano Y, Takemoto-Kimura S, Kitamura K, Kano M, Bito H
    • Organizer
      HHMI Janelia Conference “Fluorescent proteins and biological sensors IV” 口頭発表
    • Place of Presentation
      Ashburn, VA, USA
    • Year and Date
      2014-09-30
    • Data Source
      KAKENHI-PROJECT-26830043
  • [Presentation] Rational design of a high-affinity, fast, red calcium indicator R-CaMP22014

    • Author(s)
      Inoue M, Takeuchi A, Horigane S, Ohkura M, Gengyo-Ando K, Fujii H, Kamijo S, Takemoto-Kimura S, Kano M, Nakai J, Kitamura K, Bito H
    • Organizer
      生理学研究所 研究会「シナプス・神経ネットワークの機能ダイナミクス」
    • Place of Presentation
      岡崎
    • Year and Date
      2014-12-02
    • Data Source
      KAKENHI-PROJECT-26830043
  • [Presentation] Nonlinear decoding and asymmetric representation of neuronal input information by CaMKIIalpha and calcineurin

    • Author(s)
      Fujii H, Inoue M, Okuno H, Sano Y, Takemoto-Kimura S, Kitamura K, Kano M, Bito H
    • Organizer
      HHMI Janelia Conference “Fluorescent proteins and biological sensors IV” ポスター発表
    • Place of Presentation
      Ashburn, VA, USA
    • Year and Date
      2014-09-29 – 2014-09-30
    • Data Source
      KAKENHI-PROJECT-26830043
  • 1.  尾藤 晴彦
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 2.  中井 淳一
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results

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