Lee Ken-ichi 李謙一

Researcher Number	80721711
Other IDs
Affiliation (Current)	2025: 国立感染症研究所, 細菌第一部, 主任研究官
Affiliation (based on the past Project Information) *help	2019 – 2024: 国立感染症研究所, 細菌第一部, 主任研究官 2018: 国立感染症研究所, 細菌第一部, 研究員
Review Section/Research Field	Principal Investigator Basic Section 49050:Bacteriology-related Except Principal Investigator Basic Section 49050:Bacteriology-related
Keywords	Principal Investigator 志賀毒素 / 腸管出血性大腸菌 / 溶血性尿毒症症候群 / メタゲノム / メタゲノム解析 / 志賀毒素ファージ / ラムダ様ファージ / ゲノム解析 Except Principal Investigator 病原性 / ファージ / 腸管出血性大腸菌

非病原性腸内細菌への毒素ファージ伝搬による病原性発動と感染病態の解明
- Principal Investigator
  
  伊豫田淳
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 49050:Bacteriology-related
- Research Institution
  National Institute of Infectious Diseases
Study for pathogenesis and high resolution diagnosis of Shiga toxin-producing Escherichia coli infection by metagenomic analysesPrincipal Investigator
- Principal Investigator
  
  李謙一
- Project Period (FY)
  2021 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 49050:Bacteriology-related
- Research Institution
  National Institute of Infectious Diseases
Effects of phage interactions on Shiga toxin production in enterohemorragic Escherichia coliPrincipal Investigator
- Principal Investigator
  
  Lee Ken-ichi
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 49050:Bacteriology-related
- Research Institution
  National Institute of Infectious Diseases

All 2024 2021 2020 2019 2018

All Journal Article Presentation

[Journal Article] Combined usage of serodiagnosis and O antigen typing to isolate Shiga toxin-producing Escherichia coli O76:H7 from a hemolytic uremic syndrome case and genomic insights from the isolate2024
- Author(s)
  Kenichi Lee, Atsushi Iguchi, Chikako Terano, Hiroshi Hataya, Junko Isobe, Kazuko Seto, Nozomi Ishijima, Yukihiro Akeda, Makoto Ohnishi, Sunao Iyoda, EHEC Working Group in Japan
- Journal Title
  
  Microbiology Spectrum
  
  Volume: 12 Issue: 1
- DOI
  10.1128/spectrum.02355-23
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K07017, KAKENHI-PROJECT-20K07506
[Journal Article] Whole-Genome Sequencing of Shiga Toxin?Producing Escherichia coli OX18 from a Fatal Hemolytic Uremic Syndrome Case2021
- Author(s)
  Lee Kenichi、Iguchi Atsushi、Uda Kazuhiro、Matsumura Sohshi、Miyairi Isao、Ishikura Kenji、Ohnishi Makoto、Seto Junji、Ishikawa Kanako、Konishi Noriko、Obata Hiromi、Furukawa Ichiro、Nagaoka Hiromi、Morinushi Hirotaka、Hama Natsuki、Nomoto Ryohei、Nakajima Hiroshi、Kariya Hideaki、Hamasaki Mitsuhiro、Iyoda Sunao
- Journal Title
  
  Emerging Infectious Diseases
  
  Volume: 27 Issue: 5 Pages: 1509-1512
- DOI
  10.3201/eid2705.204162
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K15156, KAKENHI-PROJECT-20K07506
[Journal Article] Global distribution of epidemic-related Shiga toxin 2 encoding phages among enteroaggregative Escherichia coli2020
- Author(s)
  Kimata Keiko、Lee Kenichi、Watahiki Masanori、Isobe Junko、Ohnishi Makoto、Iyoda Sunao
- Journal Title
  
  Scientific Reports
  
  Volume: 10 Issue: 1 Pages: 11738-11738
- DOI
  10.1038/s41598-020-68462-9
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K07506, KAKENHI-PROJECT-18K15156
[Presentation] 腸管出血性大腸菌O76による溶血性尿毒症症候群の血清診断および免疫磁気ビーズを用いた原因菌の分離・性状解析2024
- Author(s)
  李謙一, 井口純, 寺野千香子, 幡谷浩史, 磯部順子, 勢戸和子, 石嶋希, 明田幸宏, 大西真, 伊豫田淳, EHEC Working Group
- Organizer
  第35回日本臨床微生物学会総会・学術集会
- Data Source
  KAKENHI-PROJECT-21K07017
[Presentation] 腸管出血性大腸菌(EHEC)におけるWGS解析2024
- Author(s)
  李謙一
- Organizer
  令和5年度北海道・東北・新潟ブロック腸管出血性大腸菌検査担当者研修会
- Invited
- Data Source
  KAKENHI-PROJECT-21K07017
[Presentation] 小児重症例から分離された腸管出血性大腸菌新規血清群OX18および関連株のゲノム解析2021
- Author(s)
  李謙一, 井口純, 宇田和宏, 松村壮史, 宮入烈, 石倉健司, 大西真, 伊豫田淳, EHEC Working Group in Japan
- Organizer
  第94回日本細菌学会総会
- Data Source
  KAKENHI-PROJECT-18K15156
[Presentation] 大規模集団感染由来O104:H4と同一のStx2aファージを有する志賀毒素産生性腸管凝集性大腸菌 (Stx-EAEC) O86の解析2020
- Author(s)
  木全恵子, 李謙一, 綿引正則, 磯部順子, 大西真, 伊豫田淳
- Organizer
  第163回日本獣医学会学術集会
- Data Source
  KAKENHI-PROJECT-18K15156
[Presentation] WGS解析によるMLVAの評価と効率的腸管出血性大腸菌 O157サーベイランス手法の確立2019
- Author(s)
  李謙一, 泉谷秀昌, 伊豫田淳, 大西真, EHEC Working Group
- Organizer
  第92回日本細菌学会総会
- Data Source
  KAKENHI-PROJECT-18K15156
[Presentation] 志賀毒素産生性腸管凝集性大腸菌 (Stx-EAEC) O86における集団感染由来O104:H4と同一のStx2aファージの獲得2019
- Author(s)
  木全恵子, 李謙一, 綿引正則, 磯部順子, 大西真, 伊豫田淳
- Organizer
  第93回日本細菌学会総会
- Data Source
  KAKENHI-PROJECT-18K15156
[Presentation] Applicability of whole genome sequencing of enterohemorrhagic Escherichia coli O111 in the national surveillance2018
- Author(s)
  Ken-ichi Lee Sunao Iyoda Tomoko Morita-Ishihara Keiko Kimata Masanori Watahiki Tsuyoshi Sekizuka Makoto Kuroda Makoto Ohnishi EHEC Working Group
- Organizer
  The 10th International Symposium on Shiga Toxin (Verocytotoxin) Producing Escherichia coli Infections
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K15156
[Presentation] HUS患者由来LEE非保有型EHECの完全長ゲノム配列解析2018
- Author(s)
  李謙一, 木全恵子, 綿引正則, 磯部順子, 伊豫田淳, 大西真, EHEC Working Group
- Organizer
  第22回腸管出血性大腸菌感染症研究会
- Data Source
  KAKENHI-PROJECT-18K15156

1. 伊豫田淳 (70300928)

# of Collaborated Projects: 2 results

# of Collaborated Products: 3 results
2. 岩瀬忠行 (80385294)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
3. 石嶋希 (60565604)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results

Lee Ken-ichi 李 謙一

Research Projects

Research Products

Co-Researchers

非病原性腸内細菌への毒素ファージ伝搬による病原性発動と感染病態の解明

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Study for pathogenesis and high resolution diagnosis of Shiga toxin-producing Escherichia coli infection by metagenomic analysesPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Effects of phage interactions on Shiga toxin production in enterohemorragic Escherichia coliPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

[Journal Article] Combined usage of serodiagnosis and O antigen typing to isolate Shiga toxin-producing Escherichia coli O76:H7 from a hemolytic uremic syndrome case and genomic insights from the isolate2024

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Whole-Genome Sequencing of Shiga Toxin?Producing Escherichia coli OX18 from a Fatal Hemolytic Uremic Syndrome Case2021

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Global distribution of epidemic-related Shiga toxin 2 encoding phages among enteroaggregative Escherichia coli2020

Author(s)

Journal Title

DOI

Data Source

[Presentation] 腸管出血性大腸菌O76による溶血性尿毒症症候群の血清診断および免疫磁気ビーズを用いた原因菌の分離・性状解析2024

Author(s)

Organizer

Data Source

[Presentation] 腸管出血性大腸菌(EHEC)におけるWGS解析2024

Author(s)

Organizer

Data Source

[Presentation] 小児重症例から分離された腸管出血性大腸菌新規血清群OX18および関連株のゲノム解析2021

Author(s)

Organizer

Data Source

[Presentation] 大規模集団感染由来O104:H4と同一のStx2aファージを有する志賀毒素産生性腸管凝集性大腸菌 (Stx-EAEC) O86の解析2020

Author(s)

Organizer

Data Source

[Presentation] WGS解析によるMLVAの評価と効率的腸管出血性大腸菌 O157サーベイランス手法の確立2019

Author(s)

Organizer

Data Source

[Presentation] 志賀毒素産生性腸管凝集性大腸菌 (Stx-EAEC) O86における集団感染由来O104:H4と同一のStx2aファージの獲得2019

Author(s)

Organizer

Data Source

[Presentation] Applicability of whole genome sequencing of enterohemorrhagic Escherichia coli O111 in the national surveillance2018

Author(s)

Organizer

Data Source

[Presentation] HUS患者由来LEE非保有型EHECの完全長ゲノム配列解析2018

Author(s)

Organizer

Data Source

Lee Ken-ichi 李謙一