Takahashi Naoki 高橋直紀

Researcher Number	80722842
Other IDs
Affiliation (Current)	2025: 北海道大学, 歯学研究院, 教授
Affiliation (based on the past Project Information) *help	2025: 北海道大学, 歯学研究院, 教授 2021 – 2025: 新潟大学, 医歯学系, 准教授 2019 – 2021: 新潟大学, 医歯学総合病院, 講師 2018 – 2019: 新潟大学, 医歯学総合病院, 助教 2017: 新潟大学, 医歯学総合研究科, 特任講師 … More 2016: 新潟大学, 医歯学総合研究科, 特任助教 2015: 新潟大学, 医歯学系, 特任助教 2015: 新潟大学, 医歯学系, 特別研究員 2014: 新潟大学, 医歯学系, 特別研究員(PD) Less
Review Section/Research Field	Principal Investigator Basic Section 57030:Conservative dentistry-related / Periodontology Except Principal Investigator Basic Section 57030:Conservative dentistry-related / Medium-sized Section 57:Oral science and related fields / Periodontology / Basic Section 57050:Prosthodontics-related
Keywords	Principal Investigator 歯周炎 / 歯周病 / 歯周病原細菌 / ペリオドンタルメディスン / 上皮細胞 / TRPV1 / 歯肉上皮細胞 / 骨再生 / 細胞外マトリックス / 骨膜細胞 … More / 腸内細菌叢 / 大腸がん / 歯周医学 / 腸管上皮細胞 / 炎症性腸疾患 / 潰瘍性腸炎 / P. gingivalis / 上皮バリア / 実験的腸炎モデルマウス / TLR / TRPチャネルタンパク / 自然免疫 / TRPイオンチャンネル / 炎症性サイトカイン / Toll-like receptor / Toll-ike receptor / TRP channel / 破骨細胞分化 / 実験的歯周炎モデルマウス / 破骨細胞 / TRPチャネル / 神経ペプチド / 歯周炎モデル / カプサイシン / CGRP / イオンチャネル … More Except Principal Investigator 歯周病 / 歯周炎 / 歯周病原細菌 / バイオフィルム / 歯周治療学 / miRNA / バイオマーカー / 咬合性外傷 / 歯周病検査 / バイオマテリアル / Metal-Phenolic Network / 口腔細菌移植 / マイクロバイオーム再構築 / 口腔がん / 遺伝因子 / 環境因子 / 口腔細菌叢 / Cellular Backpack（BP） / ドラッグデリバリーシステム / 免疫治療 / 口腔粘膜 / 幹細胞ニッチ / 口腔幹細胞 / 骨代謝 / 老化制御薬 / 骨再生薬 / 構造体 / DEL-1 / 口腔ニッチ / 老化 / 組織修復 / 口腔老化 / 骨免疫 / 骨再生 / ウェアラブルデバイス / 行動変容 / 糖尿病 / 咀嚼 / 腸内細菌叢 / 口腔細菌 / 大腸がん / ペリオドンタルメディスン / アミノ酸置換 / 機能ペプチド / 歯周病医薬 / ペプチド医薬 / 抗菌活性 / ペプチド / 根面う蝕 / リポナノカプセル / ナノカプセル / 菌血症 / 高齢者 / 光治療 / 炎症性サイトカイン / ストレスマーカー / 生理指標 / エルビウムヤグレーザー / スケーリング / 生体侵襲 / ストレス / 生体応答 / 免疫学 / 歯学 / 唾液 / 核酸医薬 / 核酸抗原 / PCSK9 / IgA / ワクチン Less

Development of a Novel Bone Regeneration Modality Based on Periosteum-Derived MatrisomePrincipal Investigator
- Principal Investigator
  
  高橋直紀
- Project Period (FY)
  2025 – 2027
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 57030:Conservative dentistry-related
- Research Institution
  Hokkaido University
Analysis of the new occlusal trauma diagnosis biomaker by the microRNA of GCF
- Principal Investigator
  
  佐藤圭祐
- Project Period (FY)
  2025 – 2027
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 57030:Conservative dentistry-related
- Research Institution
  Niigata University
Identification of Era Common Bacteria and Factors by Reconstruction of Oral Bacterial Flora
- Principal Investigator
  
  前川知樹
- Project Period (FY)
  2024 – 2025
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Review Section
  
  Medium-sized Section 57:Oral science and related fields
- Research Institution
  Niigata University
Development of new modalities in periodontal treatment using cell binding backpack
- Principal Investigator
  
  多部田康一
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 57030:Conservative dentistry-related
- Research Institution
  Niigata University
MPN武装細菌による口腔マイクロバイオームの再構築
- Principal Investigator
  
  多部田康一
- Project Period (FY)
  2023 – 2024
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Review Section
  
  Medium-sized Section 57:Oral science and related fields
- Research Institution
  Niigata University
嚥下された歯周病原細菌による腸管恒常性破綻機構の解明Principal Investigator
- Principal Investigator
  
  高橋直紀
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 57030:Conservative dentistry-related
- Research Institution
  Niigata University
Elucidation of Oral Tissue Repair and Regeneration Mechanisms by DEL-1
- Principal Investigator
  
  前川知樹
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 57030:Conservative dentistry-related
- Research Institution
  Niigata University
Analysis of oral-derived pathobiont associated with colorectal cancer
- Principal Investigator
  
  Tabeta Koichi
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Review Section
  
  Medium-sized Section 57:Oral science and related fields
- Research Institution
  Niigata University
ウェアラブルデバイスを用いた咀嚼行動変容と歯周病改善による糖尿病コントロール
- Principal Investigator
  
  堀一浩
- Project Period (FY)
  2021 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 57050:Prosthodontics-related
- Research Institution
  Niigata University
Elucidation of the TRP-TLR interaction in the pathogenesis of inflammatory diseasesPrincipal Investigator
- Principal Investigator
  
  Takahashi Naoki
- Project Period (FY)
  2019 – 2023
- Research Category
  
  Fund for the Promotion of Joint International Research (Fostering Joint International Research (A))
- Research Field
  
  Periodontology
- Research Institution
  Niigata University
Next step in the oral-gut connection: Do swallowed periodontopathogenic bacteria exacerbate colitis?Principal Investigator
- Principal Investigator
  
  Takahashi Naoki
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 57030:Conservative dentistry-related
- Research Institution
  Niigata University
Therapeutic biofilm as a new approach to the treatment of periodontal disease and root caries
- Principal Investigator
  
  Tabeta Koichi
- Project Period (FY)
  2019 – 2020
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Review Section
  
  Medium-sized Section 57:Oral science and related fields
- Research Institution
  Niigata University
Peptide drugs derived from food material for periodontal disease preventing flail and AMR
- Principal Investigator
  
  Koichi Tabeta
- Project Period (FY)
  2019 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 57030:Conservative dentistry-related
- Research Institution
  Niigata University
Analysis of Biological Response of Elderly to Post-Scaling Bacteremia and Establishment of Prophylaxis by Phototherapy
- Principal Investigator
  
  Morozumi Toshiya
- Project Period (FY)
  2017 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Periodontology
- Research Institution
  Kanagawa Dental College
  Niigata University
Interaction Between Neural and Non-Neuronal Cells in the Pathogenesis of Periodontitis.Principal Investigator
- Principal Investigator
  
  Takahashi Naoki
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Periodontology
- Research Institution
  Niigata University
Vaccines against periodontitis using DNA ORIGAMI and imidazoquinolines
- Principal Investigator
  
  KOICHI TABETA
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Periodontology
- Research Institution
  Niigata University
The Effect of TRPV1 channel in the pathogenesis of periodontitis.Principal Investigator
- Principal Investigator
  
  Takahashi Naoki
- Project Period (FY)
  2014 – 2015
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Periodontology
- Research Institution
  Niigata University

All 2022 2021 2020 2019 2018 2017 2016 2015 2014 Other

All Journal Article Presentation Book

[Book] 臨床歯周病学第3版2020
- Author(s)
  高橋直紀，多部田康一
- Total Pages
  5
- Publisher
  医歯薬出版
- ISBN
  9784263458440
- Data Source
  KAKENHI-PROJECT-18KK0434
[Book] 臨床歯周病学第3版2020
- Author(s)
  高橋直紀，多部田康一
- Total Pages
  5
- Publisher
  医歯薬出版
- ISBN
  9784263458440
- Data Source
  KAKENHI-PROJECT-19K10126
[Journal Article] Soybean peptide inhibits the biofilm of periodontopathic bacteria via bactericidal activity2022
- Author(s)
  Hnin Yu Lwin, Yukari Aoki-Nonaka, Aoi Matsugishi, Naoki Takahashi, Takumi Hiyoshi, Koichi Tabeta
- Journal Title
  
  Archives of Oral Biology
  
  Volume: 142 Pages: 105497-105497
- DOI
  10.1016/j.archoralbio.2022.105497
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19H03829
[Journal Article] Estimation of the Periodontal Inflamed Surface Area by Simple Oral Examination2021
- Author(s)
  Nomura Y, Morozumi T*, Numabe Y, Ogata Y, Nakayama Y, Sugaya T, Nakamura T, Sato S, Takashiba S, Sekino S, Yoshinari N, Hanada N, Sugano N, Fukuda M, Minabe M, Umeda M, Tabeta K, Takahashi K, Noguchi K, Kobayashi H, Takai H, Nishimura F, Suzuki F, Kakuta E, Yoshimura A, Saito A, Nakagawa T
- Journal Title
  
  Journal of Clinical Medicine
  
  Volume: 10 Issue: 4 Pages: 723-723
- DOI
  10.3390/jcm10040723
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K11984, KAKENHI-PROJECT-19K10454, KAKENHI-PROJECT-20K09942, KAKENHI-PROJECT-19K10124, KAKENHI-PROJECT-20K10303
[Journal Article] Ingestion of Porphyromonas gingivalis exacerbates colitis via intestinal epithelial barrier disruption in mice2021
- Author(s)
  Tsuzuno Takahiro、Takahashi Naoki、Yamada‐Hara Miki、Yokoji‐Takeuchi Mai、Sulijaya Benso、Aoki‐Nonaka Yukari、Matsugishi Aoi、Katakura Kyoko、Tabeta Koichi、Yamazaki Kazuhisa
- Journal Title
  
  Journal of Periodontal Research
  
  Volume: 56 Issue: 2 Pages: 275-288
- DOI
  10.1111/jre.12816
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18H04067, KAKENHI-PROJECT-19K10126, KAKENHI-PROJECT-20K18503, KAKENHI-PROJECT-18KK0434
[Journal Article] Laminin Isoforms in Human Dental Pulp: Lymphatic Vessels Express Laminin-332, and Schwann Cell?Associated Laminin-211 Modulates CD163 Expression of M2-like Macrophages2021
- Author(s)
  Yoshiba Nagako、Edanami Naoki、Ohkura Naoto、Maekawa Tomoki、Takahashi Naoki、Tsuzuno Takahiro、Maeda Takeyasu、Tabeta Koichi、Izumi Kenji、Noiri Yuichiro、Yoshiba Kunihiko
- Journal Title
  
  ImmunoHorizons
  
  Volume: 5 Issue: 12 Pages: 1008-1020
- DOI
  10.4049/immunohorizons.2100110
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K10126, KAKENHI-PROJECT-19H03828, KAKENHI-PROJECT-19K10146, KAKENHI-PROJECT-21K09914, KAKENHI-PROJECT-21K19592, KAKENHI-PROJECT-18KK0434
[Journal Article] Rice bran-derived protein fractions enhance sulforaphane-induced anti-oxidative activity in gingival epithelial cells2021
- Author(s)
  Mineo Shuhei、Takahashi Naoki、Yamada-Hara Miki、Tsuzuno Takahiro、Aoki-Nonaka Yukari、Tabeta Koichi
- Journal Title
  
  Archives of Oral Biology
  
  Volume: 129 Pages: 105215-105215
- DOI
  10.1016/j.archoralbio.2021.105215
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K10126, KAKENHI-PROJECT-20K18503, KAKENHI-PROJECT-21K19592, KAKENHI-PROJECT-18KK0434
[Journal Article] Effects of Erythromycin on Osteoclasts and Bone Resorption via DEL-1 Induction in Mice2021
- Author(s)
  Tamura Hikaru、Maekawa Tomoki、Domon Hisanori、Hiyoshi Takumi、Hirayama Satoru、Isono Toshihito、Sasagawa Karin、Yonezawa Daisuke、Takahashi Naoki、Oda Masataka、Maeda Takeyasu、Tabeta Koichi、Terao Yutaka
- Journal Title
  
  Antibiotics
  
  Volume: 10 Issue: 3 Pages: 312-312
- DOI
  10.3390/antibiotics10030312
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K09903, KAKENHI-PROJECT-18H02657, KAKENHI-PROJECT-19H03828, KAKENHI-PROJECT-20J15490, KAKENHI-PROJECT-19K22706, KAKENHI-PROJECT-17K17366, KAKENHI-PROJECT-17KK0165, KAKENHI-PROJECT-19K10126, KAKENHI-PROJECT-18KK0434
[Journal Article] Rice peptide with amino acid substitution inhibits biofilm formation by Porphyromonas gingivalis and Fusobacterium nucleatum2021
- Author(s)
  Matsugishi Aoi、Aoki-Nonaka Yukari、Yokoji-Takeuchi Mai、Yamada-Hara Miki、Mikami Yoshikazu、Hayatsu Manabu、Terao Yutaka、Domon Hisanori、Taniguchi Masayuki、Takahashi Naoki、Yamazaki Kazuhisa、Tabeta Koichi
- Journal Title
  
  Archives of Oral Biology
  
  Volume: 121 Pages: 104956-104956
- DOI
  10.1016/j.archoralbio.2020.104956
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K10126, KAKENHI-PROJECT-20K09903, KAKENHI-PROJECT-20K18503, KAKENHI-PROJECT-18KK0434, KAKENHI-PROJECT-19H03829, KAKENHI-PROJECT-19K22705, KAKENHI-PROJECT-19K24139
[Journal Article] Oral Pathobiont-Induced Changes in Gut Microbiota Aggravate the Pathology of Nonalcoholic Fatty Liver Disease in Mice2021
- Author(s)
  Yamazaki Kyoko、Kato Tamotsu、Tsuboi Yuuri、Miyauchi Eiji、Suda Wataru、Sato Keisuke、Nakajima Mayuka、Yokoji-Takeuchi Mai、Yamada-Hara Miki、Tsuzuno Takahiro、Matsugishi Aoi、Takahashi Naoki、Tabeta Koichi、Miura Nobuaki、Okuda Shujiro、Kikuchi Jun、Ohno Hiroshi、Yamazaki Kazuhisa
- Journal Title
  
  Frontiers in Immunology
  
  Volume: 12 Pages: 766170-766170
- DOI
  10.3389/fimmu.2021.766170
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K10126, KAKENHI-PROJECT-20K18502, KAKENHI-PROJECT-20K18503, KAKENHI-PROJECT-19K05907, KAKENHI-PROJECT-21K19592, KAKENHI-PROJECT-18KK0434
[Journal Article] Effect of High Fat and Fructo-Oligosaccharide Consumption on Immunoglobulin A in Saliva and Salivary Glands in Rats2021
- Author(s)
  Yamamoto Yuko、Morozumi Toshiya、Takahashi Toru、Saruta Juri、Sakaguchi Wakako、To Masahiro、Kubota Nobuhisa、Shimizu Tomoko、Kamata Yohei、Kawata Akira、Tsukinoki Keiichi
- Journal Title
  
  Nutrients
  
  Volume: 13 Issue: 4 Pages: 1252-1252
- DOI
  10.3390/nu13041252
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K10427, KAKENHI-PROJECT-18K17303, KAKENHI-PROJECT-17K11984, KAKENHI-PROJECT-21K10222, KAKENHI-PROJECT-20K18838, KAKENHI-PROJECT-21K17002
[Journal Article] Prospective Longitudinal Changes in the Periodontal Inflamed Surface Area Following Active Periodontal Treatment for Chronic Periodontitis2021
- Author(s)
  Nomura Y, Morozumi T*, Saito A, Yoshimura A, Kakuta E, Suzuki F, Nishimura F, Takai H, Kobayashi H, Noguchi K, Takahashi K, Tabeta K, Umeda M, Minabe M, Fukuda M, Sugano N, Hanada N, Yoshinari N, Sekino S, Takashiba S, Sato S, Nakamura T, Sugaya T, Nakayama Y, Ogata Y, Numabe Y, Nakagawa T
- Journal Title
  
  Journal of Clinical Medicine
  
  Volume: 10 Issue: 6 Pages: 1165-1165
- DOI
  10.3390/jcm10061165
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K11984, KAKENHI-PROJECT-19K10454, KAKENHI-PROJECT-20K09942, KAKENHI-PROJECT-19K10124, KAKENHI-PROJECT-20K10303, KAKENHI-PROJECT-20K09945
[Journal Article] Faster Short-Chain Fatty Acid Absorption from the Cecum Following Polydextrose Ingestion Increases the Salivary Immunoglobulin A Flow Rate in Rats2020
- Author(s)
  Yamamoto Yuko、Morozumi Toshiya、Takahashi Toru、Saruta Juri、To Masahiro、Sakaguchi Wakako、Shimizu Tomoko、Kubota Nobuhisa、Tsukinoki Keiichi
- Journal Title
  
  Nutrients
  
  Volume: 12 Issue: 6 Pages: 1745-1745
- DOI
  10.3390/nu12061745
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K11984, KAKENHI-PROJECT-19K10427, KAKENHI-PROJECT-20K18838, KAKENHI-PROJECT-17K11694, KAKENHI-PROJECT-18K17035
[Journal Article] Epithelial TRPV1 channels: Expression, function, and pathogenicity in the oral cavity2020
- Author(s)
  Takahashi Naoki、Tsuzuno Takahiro、Mineo Shuhei、Yamada-Hara Miki、Aoki-Nonaka Yukari、Tabeta Koichi
- Journal Title
  
  Journal of Oral Biosciences
  
  Volume: 62 Issue: 3 Pages: 235-241
- DOI
  10.1016/j.job.2020.05.005
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K10126, KAKENHI-PROJECT-20K18503, KAKENHI-PROJECT-18KK0434, KAKENHI-PROJECT-19K24139
[Journal Article] Lactobacillus-Derived Bioactive Metabolites for the Regulation of Periodontal Health: Evidences to Clinical Setting2020
- Author(s)
  Sulijaya Benso、Takahashi Naoki、Yamazaki Kazuhisa
- Journal Title
  
  Molecules
  
  Volume: 25 Issue: 9 Pages: 2088-2088
- DOI
  10.3390/molecules25092088
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K10126, KAKENHI-PROJECT-18KK0434, KAKENHI-PROJECT-18H04067
[Journal Article] Optimal Examination Sites for Periodontal Disease Evaluation: Applying the Item Response Theory Graded Response Model2020
- Author(s)
  Nomura Y, Morozumi T*, Fukuda M, Hanada N, Kakuta E, Kobayashi H, Minabe M, Nakamura T, Nakayama Y, Nishimura F, Noguchi K, Numabe Y, Ogata Y, Saito A, Sato S, Sekino S, Sugano N, Sugaya T, Suzuki F, Takahashi K, Takai H, Takashiba S, Umeda M, Yoshie H, Yoshimura A, Yoshinari N, Nakagawa T
- Journal Title
  
  Journal of Clinical Medicine
  
  Volume: 9 Issue: 11 Pages: 3754-3754
- DOI
  10.3390/jcm9113754
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K11984, KAKENHI-PROJECT-19K10124, KAKENHI-PROJECT-19K10454, KAKENHI-PROJECT-19K10471, KAKENHI-PROJECT-20K09942, KAKENHI-PROJECT-20K09945
[Journal Article] M2 Phenotype Macrophages Colocalize with Schwann Cells in Human Dental Pulp2020
- Author(s)
  Yoshiba N.、Edanami N.、Ohkura N.、Maekawa T.、Takahashi N.、Tohma A.、Izumi K.、Maeda T.、Hosoya A.、Nakamura H.、Tabeta K.、Noiri Y.、Yoshiba K.
- Journal Title
  
  Journal of Dental Research
  
  Volume: 99 Issue: 3 Pages: 329-338
- DOI
  10.1177/0022034519894957
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K10126, KAKENHI-PROJECT-19K10146, KAKENHI-PROJECT-18KK0434, KAKENHI-PROJECT-16H05516, KAKENHI-PROJECT-19K10171
[Journal Article] Nutritional supplements and periodontal disease prevention－Current understanding.2020
- Author(s)
  Aoki-Nonaka Y, Matsugishi A, Lwin HY, Takahashi N, Tabeta K
- Journal Title
  
  Curr Oral Health Rep
  
  Volume: － Issue: 2 Pages: 154-164
- DOI
  10.1007/s40496-020-00261-7
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K10126, KAKENHI-PROJECT-18K17043, KAKENHI-PROJECT-18KK0434
[Journal Article] Effect of Periodontal Disease on Diabetic Retinopathy in Type 2 Diabetic Patients: A Cross-Sectional Pilot Study2020
- Author(s)
  Yamamoto Yuko、Morozumi Toshiya、Hirata Takahisa、Takahashi Toru、Fuchida Shinya、Toyoda Masami、Nakajima Shigeru、Minabe Masato
- Journal Title
  
  Journal of Clinical Medicine
  
  Volume: 9 Issue: 10 Pages: 3234-3234
- DOI
  10.3390/jcm9103234
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K11984, KAKENHI-PROJECT-19K10454, KAKENHI-PROJECT-20K18838
[Journal Article] Erythromycin inhibits neutrophilic inflammation and mucosal disease by upregulating DEL-12020
- Author(s)
  Maekawa Tomoki、Tamura Hikaru、Domon Hisanori、Hiyoshi Takumi、Isono Toshihito、Yonezawa Daisuke、Hayashi Naoki、Takahashi Naoki、Tabeta Koichi、Maeda Takeyasu、Oda Masataka、Ziogas Athanasios、Alexaki Vasileia Ismini、Chavakis Triantafyllos、Terao Yutaka、Hajishengallis George
- Journal Title
  
  JCI Insight
  
  Volume: 5 Issue: 15 Pages: 136706-136706
- DOI
  10.1172/jci.insight.136706
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K10126, KAKENHI-PROJECT-20K09903, KAKENHI-PROJECT-20K10290, KAKENHI-PROJECT-18KK0434, KAKENHI-PROJECT-18H02657, KAKENHI-PROJECT-19H03828, KAKENHI-PROJECT-20J15490, KAKENHI-PROJECT-19K22706, KAKENHI-PROJECT-17K17366, KAKENHI-PROJECT-17KK0165
[Journal Article] A bacterial metabolite induces Nrf2-mediated anti-oxidative responses in gingival epithelial cells by activating the MAPK signaling pathway2020
- Author(s)
  Yokoji-Takeuchi Mai、Takahashi Naoki、Yamada-Hara Miki、Sulijaya Benso、Tsuzuno Takahiro、Aoki-Nonaka Yukari、Tabeta Koichi、Kishino Shigenobu、Ogawa Jun、Yamazaki Kazuhisa
- Journal Title
  
  Archives of Oral Biology
  
  Volume: 110 Pages: 104602-104602
- DOI
  10.1016/j.archoralbio.2019.104602
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K10126, KAKENHI-PROJECT-19K24139, KAKENHI-PROJECT-18KK0434, KAKENHI-PROJECT-18H04067
[Journal Article] Antimicrobial function of the polyunsaturated fatty acid KetoC in an experimental model of periodontitis2019
- Author(s)
  Sulijaya Benso、Yamada‐Hara Miki、Yokoji‐Takeuchi Mai、Matsuda‐Matsukawa Yumi、Yamazaki Kyoko、Matsugishi Aoi、Tsuzuno Takahiro、Sato Keisuke、Aoki‐Nonaka Yukari、Takahashi Naoki、Kishino Shigenobu、Ogawa Jun、Tabeta Koichi、Yamazaki Kazuhisa
- Journal Title
  
  Journal of Periodontology
  
  Volume: 90 Issue: 12 Pages: 1470-1480
- DOI
  10.1002/jper.19-0130
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K10126, KAKENHI-PROJECT-19K18990, KAKENHI-PROJECT-19K24139, KAKENHI-PROJECT-18KK0434, KAKENHI-PROJECT-18H04067
[Journal Article] Gingival epithelial barrier: regulation by beneficial and harmful microbes2019
- Author(s)
  Takahashi Naoki、Sulijaya Benso、Yamada-Hara Miki、Tsuzuno Takahiro、Tabeta Koichi、Yamazaki Kazuhisa
- Journal Title
  
  Tissue Barriers
  
  Volume: 7 Issue: 3 Pages: e1651158-e1651158
- DOI
  10.1080/21688370.2019.1651158
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K10126, KAKENHI-PROJECT-19K24139, KAKENHI-PROJECT-18KK0434
[Journal Article] Indirect regulation of PCSK9 gene in inflammatory response by Porphyromonas gingivalis infection.2019
- Author(s)
  Yokoji-Takeuchi M, Tabeta K, Takahashi N, Arimatsu K, Miyazawa H, Matsuda-Matsukawa Y, Sato K, Yamada M, Yamazaki K.
- Journal Title
  
  Heliyon
  
  Volume: 5(1) Issue: 1 Pages: e01111-e01111
- DOI
  10.1016/j.heliyon.2018.e01111
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K11827, KAKENHI-PROJECT-19K10126, KAKENHI-PROJECT-18KK0434, KAKENHI-PROJECT-18H04067
[Journal Article] Nutrition as Adjunct Therapy in Periodontal Disease Management2019
- Author(s)
  Sulijaya Benso、Takahashi Naoki、Yamazaki Kyoko、Yamazaki Kazuhisa
- Journal Title
  
  Current Oral Health Reports
  
  Volume: 6 Issue: 2 Pages: 61-69
- DOI
  10.1007/s40496-019-0216-4
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K10126, KAKENHI-PROJECT-18KK0434, KAKENHI-PROJECT-18H04067
[Journal Article] Host modulation therapy using anti-inflammatory and antioxidant agents in periodontitis: A review to a clinical translation2019
- Author(s)
  Sulijaya Benso、Takahashi Naoki、Yamazaki Kazuhisa
- Journal Title
  
  Archives of Oral Biology
  
  Volume: 105 Pages: 72-80
- DOI
  10.1016/j.archoralbio.2019.07.002
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K10126, KAKENHI-PROJECT-18KK0434
[Journal Article] The AmyI‐1‐18 peptide derived from rice inhibits alveolar bone resorption via suppression of inflammatory cytokine production induced by lipopolysaccharide and interleukin‐1β in mice2019
- Author(s)
  Aoki‐Nonaka Yukari、Tabeta Koichi、Yokoji Mai、Matsugishi Aoi、Matsuda Yumi、Takahashi Naoki、Sulijaya Benso、Domon Hisanori、Terao Yutaka、Taniguchi Masayuki、Yamazaki Kazuhisa
- Journal Title
  
  Journal of Periodontology
  
  Volume: . Issue: 10 Pages: 1160-1169
- DOI
  10.1002/jper.18-0630
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K17043, KAKENHI-PROJECT-17J40165, KAKENHI-PROJECT-16K15845, KAKENHI-PROJECT-19K10126, KAKENHI-PROJECT-18KK0434, KAKENHI-PROJECT-19H03829
[Journal Article] β 2-Microglobulin and Neutrophil Gelatinase-Associated Lipocalin, Potential Novel Urine Biomarkers in Periodontitis: A Cross-Sectional Study in Japanese.2019
- Author(s)
  Mayuka Nakajima、Michihiro Hosojima、Koichi Tabeta、Sayuri Miyauchi、Miki Yamada-Hara、Naoki Takahashi、Haruna Miyazawa、Yumi Matsuda-Matsukawa、Keisuke Sato、Noriko Sugita、Yasutaka Komatsu、Tomomi Ishikawa、Kazuhiro Akiishi、Kazuhisa Yamazaki、Kiminori Kato、Akihiko Saito、Hiromasa Yoshie
- Journal Title
  
  International Journal of Dentistry
  
  Volume: 2019 Pages: 1-10
- DOI
  10.1155/2019/1394678
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18J40011, KAKENHI-PROJECT-16K11827, KAKENHI-PROJECT-18K09572, KAKENHI-PROJECT-17K09104
[Journal Article] Effect of Ingesting Yogurt Fermented With Lactobacillus Delbrueckii Ssp. bulgaricus OLL1073R-1 on Influenza Virus-Bound Salivary IgA in Elderly Residents of Nursing Homes: A Randomized Controlled Trial2019
- Author(s)
  Yamamoto Y, Saruta J, Takahashi T, To M, Shimizu T, Hayashi T, Morozumi T, Kubota N, Kamata Y, Makino S, Kano H, Hemmi J, Asami Y, Nagai T, Misawa K, Kato S, Tsukinoki K.
- Journal Title
  
  Acta Odontologica Scandinavica
  
  Volume: 77(7) Issue: 7 Pages: 517-524
- DOI
  10.1080/00016357.2019.1609697
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K11694, KAKENHI-PROJECT-17K11984, KAKENHI-PROJECT-19K10427, KAKENHI-PROJECT-18K17035
[Journal Article] Effect of ingesting yogurt fermented with Lactobacillus delbrueckii ssp. bulgaricus OLL1073R-1 on influenza virus-bound salivary IgA in elderly residents of nursing homes: A randomized controlled trial2019
- Author(s)
  Yamamoto Y, Saruta J, Takahashi T, To M, Shimizu T, Hayashi T, Morozumi T, Kubota N, Kamata Y, Makino S, Kano H, Hemmi J, Asami Y, Nagai T, Misawa K, Kato S, Tsukinoki K
- Journal Title
  
  Acta Odontologica Scandinavica
  
  Volume: 印刷中
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K11984
[Journal Article] Aggregatibacter actinomycetemcomitans induces detachment and death of human gingival epithelial cells and fibroblasts via elastase release following leukotoxin‐dependent neutrophil lysis2019
- Author(s)
  Hiyoshi Takumi、Domon Hisanori、Maekawa Tomoki、Nagai Kosuke、Tamura Hikaru、Takahashi Naoki、Yonezawa Daisuke、Miyoshi Tomohiro、Yoshida Akihiro、Tabeta Koichi、Terao Yutaka
- Journal Title
  
  Microbiology and Immunology
  
  Volume: 63 Issue: 3-4 Pages: 100-110
- DOI
  10.1111/1348-0421.12672
- NAID
  40021899825
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K17366, KAKENHI-PROJECT-17KK0165, KAKENHI-PROJECT-16H06272, KAKENHI-PROJECT-16K11439, KAKENHI-PROJECT-17K19747, KAKENHI-PROJECT-19K06494, KAKENHI-PROJECT-19K10126, KAKENHI-PROJECT-18KK0434, KAKENHI-PROJECT-18H02974
[Journal Article] The anti-inflammatory effect of 10-oxo-trans-11-octadecenoic acid (KetoC) on RAW 264.7 cells stimulated with Porphyromonas gingivalis lipopolysaccharide2018
- Author(s)
  Sulijaya B.、Takahashi N.、Yamada M.、Yokoji M.、Sato K.、Aoki-Nonaka Y.、Nakajima T.、Kishino S.、Ogawa J.、Yamazaki K.
- Journal Title
  
  Journal of Periodontal Research
  
  Volume: 印刷中 Issue: 5 Pages: 777-784
- DOI
  10.1111/jre.12564
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15H02441, KAKENHI-PROJECT-18H04067, KAKENHI-PROJECT-16H05554, KAKENHI-PROJECT-16K11827
[Journal Article] A bacterial metabolite ameliorates periodontal pathogen-induced gingival epithelial barrier disruption via GPR40 signaling2018
- Author(s)
  Yamada M, Takahashi N, Matsuda Y, Sato K, Yokoji M, Sulijaya B, Maekawa T, Ushiki T, Mikami Y, Hayatsu M, Mizutani Y, Kishino S, Ogawa J, Arita M, Tabeta K, Maeda T, Yamazaki K
- Journal Title
  
  Scientific Reports
  
  Volume: 8 Issue: 1 Pages: 9008-9008
- DOI
  10.1038/s41598-018-27408-y
- NAID
  120006546008
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17KK0165, KAKENHI-ORGANIZER-15H05897, KAKENHI-PLANNED-15H05898, KAKENHI-PROJECT-18H04067, KAKENHI-PROJECT-16H06272, KAKENHI-PROJECT-17H06701, KAKENHI-PROJECT-16K11827, KAKENHI-PROJECT-17K19747
[Journal Article] Increased serum PCSK9, a potential biomarker to screen for periodontitis, and decreased total bilirubin associated with probing depth in a Japanese community survey2018
- Author(s)
  Tabeta K.、Hosojima M.、Nakajima M.、Miyauchi S.、Miyazawa H.、Takahashi N.、Matsuda Y.、Sugita N.、Komatsu Y.、Sato K.、Ishikawa T.、Akiishi K.、Yamazaki K.、Kato K.、Saito A.、Yoshie H.
- Journal Title
  
  Journal of Periodontal Research
  
  Volume: 印刷中 Issue: 3 Pages: 446-456
- DOI
  10.1111/jre.12533
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15H02578, KAKENHI-PROJECT-15H05052, KAKENHI-PROJECT-17H06700, KAKENHI-PROJECT-17H06701, KAKENHI-PROJECT-17K09104, KAKENHI-PROJECT-16K11827
[Journal Article] An ENU-induced splice site mutation of mouse Col1a1 causing recessive osteogenesis imperfecta and revealing a novel splicing rescue.2017
- Author(s)
  Tabeta K, Du X, Arimatsu K, Yokoji M, Takahashi N, Amizuka N, Hasegawa T, Crozat K, Maekawa T, Miyauchi S, Matsuda Y, Ida T, Kaku M, Hoebe K, Ohno K, Yoshie H, Yamazaki K, Moresco EMY, Beutler B
- Journal Title
  
  Sci. Rep.
  
  Volume: 7(1) Issue: 1 Pages: 11717-11717
- DOI
  10.1038/s41598-017-10343-9
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K11827, KAKENHI-PROJECT-15K15704, KAKENHI-PROJECT-17K19747, KAKENHI-PROJECT-15KK0337, KAKENHI-PROJECT-26293407, KAKENHI-PROJECT-15H02578, KAKENHI-PROJECT-15H04840, KAKENHI-PROJECT-16H06272, KAKENHI-PROJECT-17H06701
[Journal Article] Aggravation of collagen-induced arthritis by orally administered Porphyromonas gingivalis through modulation of the gut microbiota and gut immune system.2017
- Author(s)
  Sato K, Takahashi N, Kato T, Matsuda Y, Yokoji M, Yamada M, Nakajima T, Kondo N, Endo N, Yamamoto R, Noiri Y, Ohno H, Yamazaki K
- Journal Title
  
  Sci. Rep.
  
  Volume: 7(1) Issue: 1 Pages: 6955-6955
- DOI
  10.1038/s41598-017-07196-7
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K11827, KAKENHI-PROJECT-15H02578, KAKENHI-PROJECT-15H05021, KAKENHI-PROJECT-16H05554, KAKENHI-PROJECT-17H06701
[Journal Article] ERK5 signalling rescues intestinal epithelial turnover and tumour cell proliferation upon ERK1/2 abrogation2016
- Author(s)
  de Jong PR, Taniguchi K, Harris AR, Bertin S, Takahashi N, Duong J, Campos AD, Powis G, Corr M, Karin M, Raz E
- Journal Title
  
  Nat. Commun
  
  Volume: 17 Issue: 1 Pages: 11551-11551
- DOI
  10.1038/ncomms11551
- Peer Reviewed / Acknowledgement Compliant / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K11827
[Journal Article] Neuronal TRPV1 activation regulates alveolar bone resorption by suppressing osteoclastogenesis via CGRP2016
- Author(s)
  Takahashi N, Matsuda Y, Sato K, de Jong PR, Bertin S, Tabeta K, Yamazaki K
- Journal Title
  
  Sci. Rep
  
  Volume: 6 Issue: 1 Pages: 29294-29294
- DOI
  10.1038/srep29294
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K11827
[Journal Article] Brazilian propolis mitigates impaired glucose and lipid metabolism in experimental periodontitis in mice.2016
- Author(s)
  Nakajima M, Arimatsu K, Minagawa T, Matsuda Y, Sato K, Takahashi N, Nakajima T, Yamazaki K.
- Journal Title
  
  BMC Complement Altern Med
  
  Volume: 16 Issue: 1 Pages: 329-337
- DOI
  10.1186/s12906-016-1305-8
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-15K15763, KAKENHI-PROJECT-16K11827
[Journal Article] Ligature-induced periodontitis in mice induces elevated levels of circulating IL-6 but shows only weak effects on adipose and liver tissues.2016
- Author(s)
  3.Matsuda Y, Kato T, Takahashi N, Nakajima M, Arimatsu K, Minagawa T, Sato K, Ohno H, Yamazaki K.
- Journal Title
  
  Journal of Periodontal Research
  
  Volume: 51 Issue: 5 Pages: 639-646
- DOI
  10.1111/jre.12344
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-15H02578, KAKENHI-PROJECT-25463216, KAKENHI-PROJECT-26861808, KAKENHI-PROJECT-16K11827
[Journal Article] The TRPA1 ion channel is expressed in CD4+ T cells and restrains T-cell-mediated colitis through inhibition of TRPV1.2016
- Author(s)
  Bertin S, Aoki-Nonaka Y, Lee J, de Jong PR, Kim P, Han T, Yu T, To K, Takahashi N, Boland BS, Chang JT, Ho SB, Herdman S, Corr M, Franco A, Sharma S, Dong H, Akopian AN, Raz E
- Journal Title
  
  Gut
  
  Volume: 2015 Issue: 9 Pages: 310710-310710
- DOI
  10.1136/gutjnl-2015-310710
- Peer Reviewed / Acknowledgement Compliant / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K11827
[Journal Article] Epithelial TRPV1 signaling accelerates gingival epithelial cell proliferation.2014
- Author(s)
  Takahashi N, Matsuda Y, Yamada H, Tabeta K, Nakajima T, Murakami S, Yamazaki K
- Journal Title
  
  J Dent Res.
  
  Volume: 93(11) Issue: 11 Pages: 1141-1147
- DOI
  10.1177/0022034514552826
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-13J04959, KAKENHI-PROJECT-25463216, KAKENHI-PROJECT-26861808
[Presentation] 糖尿病モデルラットにおける顎下腺組織IgA濃度とplgR発現量の解析2022
- Author(s)
  山本裕子，猿田樹理，坂口和歌子，窪田展久，東雅啓，清水智子，両角俊哉，高橋徹，高垣裕子，槻木恵一
- Organizer
  第76回日本栄養・食糧学会大会
- Data Source
  KAKENHI-PROJECT-17K11984
[Presentation] 短鎖脂肪酸経口摂取がラット唾液中IgA分泌速度に与える影響の検討2022
- Author(s)
  山本裕子，高橋徹，猿田樹理，坂口和歌子，両角俊哉，東雅啓，槻木恵一
- Organizer
  第1回日本唾液ケア研究会学術集会
- Data Source
  KAKENHI-PROJECT-17K11984
[Presentation] Antioxidant effect of food-derived peptide in human gingival epithelial cells2021
- Author(s)
  Mineo S, Takahashi N, Tsuzuno T, Aoki-Nonaka Y, Tabeta K
- Organizer
  99th General Session of the IADR
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18KK0434
[Presentation] 歯周病のポケット選定における代表歯・部位の選定2021
- Author(s)
  両角俊哉, 高柴正悟, 三邉正人, 野村義明, 福田光男, 花田信弘, 角田衣理加, 小林宏明,中村利明, 中山洋平, 西村英紀, 野口和行, 沼部幸博, 小方頼昌, 齋藤淳, 佐藤聡, 関野諭, 菅野直之, 菅谷勉, 鈴木史彦, 多部田康一, 高橋慶壮, 高井英樹,梅田誠, 吉江弘正, 吉村篤利, 吉成伸夫, 中川種昭
- Organizer
  第14回日本口腔検査学会総会・学術大会
- Data Source
  KAKENHI-PROJECT-17K11984
[Presentation] ヒト歯肉上皮細胞における米糠由来ペプチドによる抗酸化作用の検証2021
- Author(s)
  峯尾修平，高橋直紀，都野隆博，野中由香莉，多部田康一
- Organizer
  第64回春季日本歯周病学会学術大会
- Data Source
  KAKENHI-PROJECT-21K19592
[Presentation] Antioxidant effect of food-derived peptide in human gingival epithelial cells.2021
- Author(s)
  Mineo S, Takahashi N, Tsuzuno T, Aoki-Nonaka Y, Tabeta K
- Organizer
  99th General Session of the IADR
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K19592
[Presentation] 超音波スケーラーから発生するエアロゾル特性と口腔内外吸引装置による拡散防止効果①－感水試験紙を用いた飛散方向および距離の検討－2021
- Author(s)
  峯尾修平，高橋直紀，多部田康一
- Organizer
  第64回秋季日本歯周病学会学術大会
- Data Source
  KAKENHI-PROJECT-19K10126
[Presentation] ヒト歯肉上皮細胞における米糠由来ペプチドによる抗酸化作用の検証2021
- Author(s)
  峯尾修平，高橋直紀，都野隆博，野中由香莉，多部田康一
- Organizer
  第64回春季日本歯周病学会学術大会
- Data Source
  KAKENHI-PROJECT-19K10126
[Presentation] Antioxidant effect of food-derived peptide in human gingival epithelial cells2021
- Author(s)
  Mineo S, Takahashi N, Tsuzuno T, Aoki-Nonaka Y, Tabeta K
- Organizer
  99th General Session of the IADR
- Data Source
  KAKENHI-PROJECT-19K10126
[Presentation] 歯周病ポケット検査における代表歯・部位の選定2021
- Author(s)
  両角俊哉, 野村義明, 中川種昭, 沼部幸博, 菅谷勉, 佐藤聡, 野口和行, 吉成伸夫, 吉村篤利, 西村英紀, 齋藤淳, 福田光男, 小林宏明, 菅野直之, 多部田康一, 高橋慶壮, 梅田誠, 高柴正悟, 三邉正人, 小方賴昌
- Organizer
  第56回神奈川歯科大学学会総会
- Data Source
  KAKENHI-PROJECT-17K11984
[Presentation] 超音波スケーラーから発生するエアロゾル特性と口腔内外吸引装置の拡散防止効果②－小粒径エアロゾルの粒径分布とその吸引効果の検討－2021
- Author(s)
  高橋直紀，峯尾修平，多部田康一
- Organizer
  第64回秋季日本歯周病学会学術大会
- Data Source
  KAKENHI-PROJECT-19K10126
[Presentation] 超音波スケーラーから発生するエアロゾル特性と口腔内外吸引装置の拡散防止効果②－小粒径エアロゾルの粒径分布とその吸引効果の検討－2021
- Author(s)
  高橋直紀，峯尾修平，多部田康一
- Organizer
  第64回秋季日本歯周病学会学術大会
- Data Source
  KAKENHI-PROJECT-18KK0434
[Presentation] 超音波スケーラーから発生するエアロゾル特性と口腔内外吸引装置による拡散防止効果①－感水試験紙を用いた飛散方向および距離の検討－2021
- Author(s)
  峯尾修平，高橋直紀，多部田康一
- Organizer
  第64回秋季日本歯周病学会学術大会
- Data Source
  KAKENHI-PROJECT-18KK0434
[Presentation] Experimental animal model in periodontal research2021
- Author(s)
  Takahashi N
- Organizer
  15th International Dental Collaboration of the Mekong River Region (IDCMR) Pre-conference workshops
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K10126
[Presentation] ヒト歯肉上皮細胞における米糠由来ペプチドによる抗酸化作用の検証2021
- Author(s)
  峯尾修平，高橋直紀，都野隆博，野中由香莉，多部田康一
- Organizer
  第64回春季日本歯周病学会学術大会
- Data Source
  KAKENHI-PROJECT-18KK0434
[Presentation] Experimental animal model in periodontal research2021
- Author(s)
  Takahashi N
- Organizer
  15th International Dental Collaboration of the Mekong River Region (IDCMR) Pre-conference workshops
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18KK0434
[Presentation] 歯周病評価における最適検査部位の選定 ―項目反応理論 Graded response modelの応用―2021
- Author(s)
  両角俊哉, 野村義明, 福田光男, 花田信弘, 角田衣理加, 小林宏明, 三邉正人, 中村利明, 中山洋平, 西村英紀, 野口和行, 沼部幸博, 小方頼昌, 齋藤淳, 佐藤聡, 関野諭, 菅野直之, 菅谷勉, 鈴木史彦, 多部田康一, 高橋慶壮, 高井英樹, 高柴正悟, 梅田誠, 吉江弘正, 吉村篤利, 吉成伸夫, 中川種昭
- Organizer
  第64回春季日本歯周病学会学術大会
- Data Source
  KAKENHI-PROJECT-17K11984
[Presentation] 歯肉上皮細胞における抗酸化ストレス応答を活性化させる食物由来ペプチドの探索2020
- Author(s)
  峯尾修平，高橋直紀，都野隆博，野中由香莉，田村光，多部田康一
- Organizer
  2020年度春季学術大会(第152回)
- Data Source
  KAKENHI-PROJECT-18KK0434
[Presentation] 腸内細菌叢の変動を介した歯周病のNAFLDへの影響2020
- Author(s)
  山崎恭子，中島麻由佳，竹内麻衣，原実生，都野隆博，松岸葵，松川由実，佐藤圭祐，高橋直紀，多部田康一，坪井裕理，菊池淳，加藤完，大野博司，山崎和久
- Organizer
  第24回腸内細菌学会学術集会
- Data Source
  KAKENHI-PROJECT-18KK0434
[Presentation] Gingival epithelial cells: a possible target for host modulation therapy?2020
- Author(s)
  Takahashi N
- Organizer
  International Collaborative Symposium on Development of Human Resources in Practical Oral Health and Treatment
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18KK0434
[Presentation] Porphyromonas gingivalis aggravates experimental induced colitis in mice.2020
- Author(s)
  Tsuzuno T, Takahashi N, Yamada-Hara M, Yokoji-Takeuchi M, Aoki-Nonaka Y, Matsugishi A, Tabeta K, Yamazaki K
- Organizer
  International Collaborative Symposium on Development of Human Resources in Practical Oral Health and Treatment
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18KK0434
[Presentation] Porphyromonas gingivalis経口投与は腸内細菌の変化を介してNAFLD病態に影響を与える2020
- Author(s)
  山崎恭子，中島麻由佳，竹内麻衣，原実生，都野隆博，松岸葵，松川由実，佐藤圭祐，高橋直紀，多部田康一，山崎和久
- Organizer
  令和2年新潟歯学会第2回例会
- Data Source
  KAKENHI-PROJECT-18KK0434
[Presentation] 歯肉上皮細胞における抗酸化ストレス応答を活性化させる食物由来ペプチドの探索2020
- Author(s)
  峯尾修平，高橋直紀，都野隆博，野中由香莉，田村光，多部田康一
- Organizer
  日本歯科保存学会2020年度春季学術大会(第152回)
- Data Source
  KAKENHI-PROJECT-19K10126
[Presentation] 歯肉上皮細胞に発現するTRPV1活性化による抗炎症性作用の解析2020
- Author(s)
  都野隆博，高橋直紀，峯尾修平，原実生，野中由香莉，多部田康一
- Organizer
  日本歯科保存学会2020年度春季学術大会(第152回)
- Data Source
  KAKENHI-PROJECT-18KK0434
[Presentation] Porphyromonas gingivalis経口投与は腸内細菌の変化を介してNAFLD病態に影響を与える2020
- Author(s)
  山崎恭子，中島麻由佳，竹内麻衣，原実生，都野隆博，松岸葵，松川由実，佐藤圭祐，高橋直紀，多部田康一，山崎和久
- Organizer
  令和2年新潟歯学会第2回例会
- Data Source
  KAKENHI-PROJECT-19K10126
[Presentation] Porphyromonas gingivalis aggravates experimental induced colitis in mice.2020
- Author(s)
  Tsuzuno T, Takahashi N, Yamada-Hara M, Yokoji-Takeuchi M, Aoki-Nonaka Y, Matsugishi A, Tabeta K, Yamazaki K
- Organizer
  Collaborative Symposium on Development of Human Resources in Practical Oral Health and Treatment
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K10126
[Presentation] Gingival epithelial cells: a possible target for host modulation therapy?2020
- Author(s)
  Takahashi N
- Organizer
  Collaborative Symposium on Development of Human Resources in Practical Oral Health and Treatment
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K10126
[Presentation] 腸内細菌叢の変動を介した歯周病のNAFLDへの影響2020
- Author(s)
  山崎恭子，中島麻由佳，竹内麻衣，原実生，都野隆博，松岸葵，松川由実，佐藤圭祐，高橋直紀，多部田康一，坪井裕理，菊池淳，加藤完，大野博司，山崎和久
- Organizer
  第24回腸内細菌学会学術集会
- Data Source
  KAKENHI-PROJECT-19K10126
[Presentation] ヒト歯肉上皮細胞における抗酸化ストレス応答を増強する食物由来ペプチドの探索2020
- Author(s)
  峯尾修平，高橋直紀，都野隆博，野中由香莉，多部田康一
- Organizer
  令和2年度新潟歯学会第2回例会
- Data Source
  KAKENHI-PROJECT-19K10126
[Presentation] ヒト歯肉上皮細胞における抗酸化ストレス応答を増強する食物由来ペプチドの探索. 令和2年度新潟歯学会第2回例会2020
- Author(s)
  峯尾修平，高橋直紀，都野隆博，野中由香莉，多部田康一
- Organizer
  令和2年度新潟歯学会第2回例会
- Data Source
  KAKENHI-PROJECT-18KK0434
[Presentation] 歯肉上皮細胞に発現するTRPV1活性化による抗炎症性作用の解析2020
- Author(s)
  都野隆博，高橋直紀，峯尾修平，原実生，野中由香莉，多部田康一
- Organizer
  日本歯科保存学会2020年度春季学術大会(第152回)
- Data Source
  KAKENHI-PROJECT-19K10126
[Presentation] Neuronal TRPV1 activation prevents alveolar bone resorption via CGRP.2019
- Author(s)
  Takahashi N
- Organizer
  97th General Session of the IADR
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18KK0434
[Presentation] Interaction Between Neural and Non-Neuronal Cells in the Pathogenesis of Periodontitis.2019
- Author(s)
  Takahashi N, Matsuda-Matsukawa Y, Sato K, Maeda T, Yamazaki K, Tabeta K
- Organizer
  International Collaborative Symposium on Development of Human Resources in Practical Oral Health and Treatment
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K11827
[Presentation] 実験的腸炎モデルマウスにおけるPorphyromonas gingivalisによる腸炎増悪メカニズムの解析.2019
- Author(s)
  都野隆博，高橋直紀，竹内麻衣，原実生，多部田康一，山崎和久
- Organizer
  第62回秋季日本歯周病学会学術大会
- Data Source
  KAKENHI-PROJECT-18KK0434
[Presentation] A bacterial metabolite prevents P. gingivalis-induced gingival epithelial barrier disruption in mice model2019
- Author(s)
  Takahashi N, Yamada M, Sulijaya B, Maeda T, Tabeta K, Yamazaki K
- Organizer
  International Niigata-Taiwan Universities Collaborative Dental Research Symposium 2019
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K11827
[Presentation] Oral administration of Porphyromonas gingivalis aggravates intestinal inflammation in mice.2019
- Author(s)
  Tsuzuno T, Takahashi N, Yokoji M, Yamada-Hara M, Nakajima M, Tabeta K, Yamazaki K
- Organizer
  97th General Session of the IADR
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K10126
[Presentation] 実験的腸炎モデルマウスにおけるPorphyromonas gingivalisによる腸炎増悪メカニズムの解析.2019
- Author(s)
  都野隆博，高橋直紀，竹内麻衣，原実生，多部田康一，山崎和久
- Organizer
  第62回秋季日本歯周病学会学術大会
- Data Source
  KAKENHI-PROJECT-19K10126
[Presentation] Porphyromonas gingivalisが腸管上皮バリア機能へ及ぼす影響の解析.2019
- Author(s)
  都野隆博，高橋直紀，竹内麻衣，原実生，中島麻由佳，多部田康一，山崎和久
- Organizer
  日本歯科保存学会2019年度春季学術大会
- Data Source
  KAKENHI-PROJECT-19K10126
[Presentation] Porphyromonas gingivalis口腔投与がDSS誘導性実験的腸炎に及ぼす影響の解析.2019
- Author(s)
  都野隆博，高橋直紀，竹内麻衣，原実生，中島麻由佳，多部田康一，山崎和久
- Organizer
  第62回春季日本歯周病学会学術大会
- Data Source
  KAKENHI-PROJECT-18KK0434
[Presentation] Effect of Ingesting Yogurt Fermented with Lactobacillus delbrueckii ssp. bulgaricus OLL1073R-1 on Influenza Virus-Bound Salivary IgA in Elderly People2019
- Author(s)
  Yamamoto Y, Saruta J, Takahashi T, To M, Shimizu T, Morozumi T, Kubota N, Makino S, Kano H, Tsukinoki K
- Organizer
  13th International Scientific Conference on Probiotics, Prebiotics, Gut Microbiota and Health
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K11984
[Presentation] Porphyromonas gingivalisが腸管上皮バリア機能へ及ぼす影響の解析.2019
- Author(s)
  都野隆博，高橋直紀，竹内麻衣，原実生，中島麻由佳，多部田康一，山崎和久
- Organizer
  日本歯科保存学会2019年度春季学術大会
- Data Source
  KAKENHI-PROJECT-18KK0434
[Presentation] Porphyromonas gingivalis口腔投与がDSS誘導性実験的腸炎に及ぼす影響の解析.2019
- Author(s)
  都野隆博，高橋直紀，竹内麻衣，原実生，中島麻由佳，多部田康一，山崎和久
- Organizer
  第62回春季日本歯周病学会学術大会
- Data Source
  KAKENHI-PROJECT-19K10126
[Presentation] Oral administration of Porphyromonas gingivalis aggravates intestinal inflammation in mice.2019
- Author(s)
  Tsuzuno T, Takahashi N, Yokoji M, Yamada-Hara M, Nakajima M, Tabeta K, Yamazaki K
- Organizer
  97th General Session of the IADR
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18KK0434
[Presentation] Neuronal TRPV1 activation prevents alveolar bone resorption via CGRP.2019
- Author(s)
  Takahashi N
- Organizer
  97th General Session of the IADR
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K10126
[Presentation] Dysbiosis of gut microbiome in Japanese patients with periodontitis.2019
- Author(s)
  Yamazaki K, Sato K, Nakajima T, Muyazawa H, Takahashi N, Yamada-Hara M, Yokoji M, Yamazaki K
- Organizer
  7th General Session of the IADR
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K10126
[Presentation] 10-Hydroxy-cis-12-Octadecenoic Acid Ameliorates Gingival Epithelial Barrier Disruption via GPR40-ERK Signaling2018
- Author(s)
  Takahashi N, Yamada M, Matsuda Y, Sato K, Yokoji M, Sulijaya B, Tabeta K, Nakajima T, Maeda T, Yamazaki K
- Organizer
  96th General session of the IADR
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K11827
[Presentation] 広汎型重度慢性歯周炎患者において歯周組織再生療法と局所矯正治療により改善を認めた一症例2018
- Author(s)
  両角俊哉,保苅崇大,野村隆,久保田健彦,小松康高,高橋直紀,奥田一博,三辺正人,吉江弘正
- Organizer
  第61回春季日本歯周病学会学術大会
- Data Source
  KAKENHI-PROJECT-17K11984
[Presentation] 歯周病と全身疾患の関連メカニズム―腸内細菌叢を介する新たな仮説―2017
- Author(s)
  高橋直紀
- Organizer
  第71回日本口腔科学会学術集会
- Data Source
  KAKENHI-PROJECT-16K11827
[Presentation] Effect of resveratrol on occlusal trauma-induced bone loss in mice.2017
- Author(s)
  Matsuda Y, Okui T, Minagawa T, Tabeta K, Takahashi N, Sato K, Yamada M, Yokoji M, Nakajima T, Yamazaki K
- Organizer
  95th General Session & Exhibition of the IADR
- Place of Presentation
  米国サンフランシスコ
- Year and Date
  2017-03-22
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K11827
[Presentation] 歯肉縁下細菌と血清抗体価を用いた慢性歯周炎進行の評価：24ヵ月多施設前向きコホート研究2017
- Author(s)
  両角俊哉、角田衣理加、野村義明、中川種昭、野口和行、原宜興、西村英紀、梅田誠、野口俊英、吉成伸夫、沼部幸博、伊藤公一、和泉雄一、小方頼昌、三邉正人、齋藤淳、佐藤聡、高橋慶壮、川浪雅光、花田信弘、高柴正悟、吉江弘正
- Organizer
  第60回春季日本歯周病学会学術大会
- Data Source
  KAKENHI-PROJECT-17K11984
[Presentation] A novel mechanism linking periodontitis and rheumatoid arthritis.2017
- Author(s)
  Sato K, Takahashi N, Matsuda Y, Yamada M, Yokoji M, Tabeta K, Nakajima T, Yamazaki K
- Organizer
  95th General Session & Exhibition of the IADR
- Place of Presentation
  米国サンフランシスコ
- Year and Date
  2017-03-22
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K11827
[Presentation] 歯肉縁下細菌と血清抗体価による慢性歯周炎進行の予知判定：24ヵ月多施設前向きコホート研究2017
- Author(s)
  両角俊哉,中川種昭,野口和行,原宜興,西村英紀,梅田誠,野口俊英,吉成伸夫,沼部幸博, 伊藤公一,和泉雄一,小方頼昌,三邉正人,齋藤淳,佐藤聡,高橋慶壮,川浪雅光,花田信弘, 高柴正悟,吉江弘正
- Organizer
  日本歯科保存学会2017年度春季学術大会
- Data Source
  KAKENHI-PROJECT-17K11984
[Presentation] Neuronal TRPV1 activation inhibits alveolar bone resorption via neuropeptide release.2017
- Author(s)
  Takahashi N, Matsuda Y, Sato K, Tabeta K, Yamazaki K, Maeda T
- Organizer
  95th General Session & Exhibition of the IADR
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K11827
[Presentation] Neuronal TRPV1 activation regulates alveolar bone resorption by suppressing osteoclastogenesis via CGRP.2017
- Author(s)
  Takahashi N
- Organizer
  International Symposium on Development of Human Resources in Practical Oral Health and Treatment
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K11827
[Presentation] A bacterial metabolite ameliorates P. gingivalis-induced gingival epithelial barrier disruption.2017
- Author(s)
  Yamada M, Takahashi N, Matsuda Y, Sato K, Yokoji M, Tabeta K, Nakajima T, Yamazaki K
- Organizer
  95th General Session & Exhibition of the IADR
- Place of Presentation
  米国サンフランシスコ
- Year and Date
  2017-03-22
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K11827
[Presentation] 細菌抗原によるPCSK9産生の誘導機構2016
- Author(s)
  横地麻衣, 多部田康一, 宮澤春菜, 野中由香莉, 高橋直紀, 松田由実, 佐藤圭祐, 山田実生, 伊藤晴江, 中島貴子, 山崎和久
- Organizer
  日本歯科保存学会2016年度秋季学術大会
- Place of Presentation
  キッセイ文化ホール（長野県松本市）
- Year and Date
  2016-10-28
- Data Source
  KAKENHI-PROJECT-15H05052
[Presentation] Neuronal TRPV1 activation regulates alveolar bone resorption by osteoclasts via CGRP2015
- Author(s)
  Takahashi N, Matsuda Y, Sato K, Tabeta K, Yamazaki K
- Organizer
  63nd Annual meeting of JADR
- Place of Presentation
  福岡国際会議場(福岡県福岡市)
- Year and Date
  2015-10-30
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26861808
[Presentation] Neuronal TRPV1 prevents alveolar bone resorption in experimental periodontitis mice model.2015
- Author(s)
  Takahashi N, Matsuda Y, Sato K, Yamada H, Tabeta K, Yamazaki K
- Organizer
  11th Asian Pacific Society of Periodontology Meeting
- Place of Presentation
  Bali (Indonesia)
- Year and Date
  2015-10-08
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26861808
[Presentation] 歯肉上皮細胞におけるカプサイシン受容体TRPV1の発現および機能解析2014
- Author(s)
  高橋直紀、松田由実、山田ひとみ、中島貴子、多部田康一、村上伸也、山崎和久
- Organizer
  日本歯科保存学会2014年度春季学術大会（第140回）
- Place of Presentation
  大津市
- Year and Date
  2014-06-19
- Data Source
  KAKENHI-PROJECT-26861808
[Presentation] TRPV1 Signaling Accelerates Cell Proliferation of Gingival Epithelial Cells.
- Author(s)
  Takahashi N, Matsuda Y, Tabeta K, Yamazaki K
- Organizer
  92nd General session of the IADR
- Place of Presentation
  Cape Town
- Year and Date
  2014-06-25 – 2014-06-28
- Data Source
  KAKENHI-PROJECT-26861808

1. KOICHI TABETA (20401763)

# of Collaborated Projects: 13 results

# of Collaborated Products: 40 results
2. 野中由香莉 (40710520)

# of Collaborated Projects: 5 results

# of Collaborated Products: 2 results
3. 寺尾豊 (50397717)

# of Collaborated Projects: 4 results

# of Collaborated Products: 1 results
4. YAMAZAKI Kazuhisa (00182478)

# of Collaborated Projects: 2 results

# of Collaborated Products: 16 results
5. 藤本啓二 (70229045)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
6. 谷口浩二 (20627020)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
7. 前川知樹 (50625168)

# of Collaborated Projects: 2 results

# of Collaborated Products: 2 results
8. 中島麻由佳 (90804542)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
9. Morozumi Toshiya (20444151)

# of Collaborated Projects: 1 results

# of Collaborated Products: 15 results
10. 小松康高 (40422597)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
11. 保苅崇大 (30827621)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
12. 宮沢春菜 (50733721)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
13. 片倉響子 (70423788)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
14. 谷口正之 (00163634)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
15. 寺井崇二 (00332809)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
16. 佐藤裕樹 (50644556)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
17. 高橋一也 (90793068)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
18. 中島尚 (80912013)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
19. 堀一浩 (70379080)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
20. 吉村将悟 (20909395)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
21. 小野高裕 (30204241)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
22. 曽根博仁 (30312846)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
23. 村上和裕 (60804490)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
24. 土門久哲 (00594350)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
25. 福田達也 (90805160)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
26. 池田真由美 (90965708)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
27. 岩尾康範 (30433022)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
28. Rosenkranz Andrea (20985858)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
29. 米澤大輔 (90711896)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
30. 江島広貴 (00724543)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
31. 永田昌毅 (10242439)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
32. 佐藤圭祐 (80828905)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
33. KISHINO Shigenobu

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
34. SUGIMOTO Masahiro

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
35. 小川順

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
36. 加藤完

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
37. 大野博司

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
38. 槻木恵一

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
39. 猿田樹理

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
40. 東雅啓

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
41. 高橋徹

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
42. 山本裕子

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Takahashi Naoki 高橋 直紀

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Development of a Novel Bone Regeneration Modality Based on Periosteum-Derived MatrisomePrincipal Investigator

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嚥下された歯周病原細菌による腸管恒常性破綻機構の解明Principal Investigator

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Elucidation of the TRP-TLR interaction in the pathogenesis of inflammatory diseasesPrincipal Investigator

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Next step in the oral-gut connection: Do swallowed periodontopathogenic bacteria exacerbate colitis?Principal Investigator

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Interaction Between Neural and Non-Neuronal Cells in the Pathogenesis of Periodontitis.Principal Investigator

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Takahashi Naoki 高橋直紀

[Book] 臨床歯周病学第3版2020

[Book] 臨床歯周病学第3版2020