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Takahashi Naoki  高橋 直紀

ORCIDConnect your ORCID iD *help
Researcher Number 80722842
Other IDs
Affiliation (Current) 2020: 新潟大学, 医歯学総合病院, 講師
Affiliation (based on the past Project Information) *help 2019 – 2020: 新潟大学, 医歯学総合病院, 講師
2018: 新潟大学, 医歯学総合病院, 助教
2017: 新潟大学, 医歯学総合研究科, 特任講師
2016: 新潟大学, 医歯学総合研究科, 特任助教
2015: 新潟大学, 医歯学系, 特任助教
2015: 新潟大学, 医歯学系, 特別研究員
2014: 新潟大学, 医歯学系, 特別研究員(PD)
Review Section/Research Field
Principal Investigator
Periodontology / Basic Section 57030:Conservative dentistry-related
Except Principal Investigator
Periodontology / Basic Section 57030:Conservative dentistry-related / Medium-sized Section 57:Oral science and related fields
Keywords
Principal Investigator
歯周炎 / 歯肉上皮細胞 / TRPV1 / 歯周病 / イオンチャネル / CGRP / カプサイシン / 歯周炎モデル / 神経ペプチド / TRPチャネル … More / 破骨細胞 / 実験的歯周炎モデルマウス / 破骨細胞分化 / TRPイオンチャンネル / Toll-like receptor / ペリオドンタルメディスン / 歯周病原細菌 / 潰瘍性腸炎 / 炎症性腸疾患 / P. gingivalis / 腸管上皮細胞 … More
Except Principal Investigator
歯周病 / バイオフィルム / ワクチン / IgA / PCSK9 / 核酸抗原 / 核酸医薬 / 唾液 / 歯学 / 免疫学 / 歯周炎 / 生体応答 / 高齢者 / スケーリング / 光治療 / 菌血症 / 歯周治療学 / 歯周病医薬 / 機能ペプチド / 歯周病原細菌 / ペプチド医薬 / アミノ酸置換 / リポナノカプセル / ナノカプセル / 根面う蝕 Less
  • Research Projects

    (8 results)
  • Research Products

    (59 results)
  • Co-Researchers

    (41 People)
  •  Elucidation of the TRP-TLR interaction in the pathogenesis of inflammatory diseasesPrincipal InvestigatorOngoing

    • Principal Investigator
      高橋 直紀
    • Project Period (FY)
      2019 – 2021
    • Research Category
      Fund for the Promotion of Joint International Research (Fostering Joint International Research (A))
    • Research Field
      Periodontology
    • Research Institution
      Niigata University
  •  Peptide drugs derived from food material for periodontal disease preventing flail and AMROngoing

    • Principal Investigator
      多部田 康一
    • Project Period (FY)
      2019 – 2022
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Review Section
      Basic Section 57030:Conservative dentistry-related
    • Research Institution
      Niigata University
  •  口腔-腸管連関の新展開:嚥下された歯周病原細菌は腸炎を悪化させるか?Principal InvestigatorOngoing

    • Principal Investigator
      高橋 直紀
    • Project Period (FY)
      2019 – 2021
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 57030:Conservative dentistry-related
    • Research Institution
      Niigata University
  •  Therapeutic biofilmによる歯周病・根面う蝕治療アプローチの転換Ongoing

    • Principal Investigator
      多部田 康一
    • Project Period (FY)
      2019 – 2020
    • Research Category
      Grant-in-Aid for Challenging Research (Exploratory)
    • Review Section
      Medium-sized Section 57:Oral science and related fields
    • Research Institution
      Niigata University
  •  スケーリング後菌血症に対する高齢者生体応答の解析と光治療による予防法の確立Ongoing

    • Principal Investigator
      両角 俊哉
    • Project Period (FY)
      2017 – 2020
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Periodontology
    • Research Institution
      Kanagawa Dental College
      Niigata University
  •  Interaction Between Neural and Non-Neuronal Cells in the Pathogenesis of Periodontitis.Principal Investigator

    • Principal Investigator
      Takahashi Naoki
    • Project Period (FY)
      2016 – 2018
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Periodontology
    • Research Institution
      Niigata University
  •  Vaccines against periodontitis using DNA ORIGAMI and imidazoquinolines

    • Principal Investigator
      KOICHI TABETA
    • Project Period (FY)
      2015 – 2017
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Periodontology
    • Research Institution
      Niigata University
  •  The Effect of TRPV1 channel in the pathogenesis of periodontitis.Principal Investigator

    • Principal Investigator
      Takahashi Naoki
    • Project Period (FY)
      2014 – 2015
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      Periodontology
    • Research Institution
      Niigata University

All 2020 2019 2018 2017 2016 2015 2014 Other

All Journal Article Presentation Book

  • [Book] 臨床歯周病学 第3版2020

    • Author(s)
      高橋直紀,多部田康一
    • Total Pages
      5
    • Publisher
      医歯薬出版
    • ISBN
      9784263458440
    • Data Source
      KAKENHI-PROJECT-18KK0434
  • [Book] 臨床歯周病学 第3版2020

    • Author(s)
      高橋直紀,多部田康一
    • Total Pages
      5
    • Publisher
      医歯薬出版
    • ISBN
      9784263458440
    • Data Source
      KAKENHI-PROJECT-19K10126
  • [Journal Article] Nutritional Supplements and Periodontal Disease Prevention -Current Understanding2020

    • Author(s)
      Aoki-Nonaka Y, Matsugishi A, Lwin HY, Takahashi N, Tabeta K
    • Journal Title

      Curr Oral Health Rep

      Volume: -

    • DOI

      10.1007/s40496-020-00261-7

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19K10126, KAKENHI-PROJECT-18K17043, KAKENHI-PROJECT-18KK0434
  • [Journal Article] A bacterial metabolite induces Nrf2-mediated anti-oxidative responses in gingival epithelial cells by activating the MAPK signaling pathway2020

    • Author(s)
      Yokoji-Takeuchi Mai、Takahashi Naoki、Yamada-Hara Miki、Sulijaya Benso、Tsuzuno Takahiro、Aoki-Nonaka Yukari、Tabeta Koichi、Kishino Shigenobu、Ogawa Jun、Yamazaki Kazuhisa
    • Journal Title

      Archives of Oral Biology

      Volume: 110 Pages: 104602-104602

    • DOI

      10.1016/j.archoralbio.2019.104602

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-19K10126, KAKENHI-PROJECT-19K24139, KAKENHI-PROJECT-18KK0434
  • [Journal Article] M2 phenotype macrophages colocalize with Schwann cells in human Dental Pulp2020

    • Author(s)
      Yoshiba N.、Edanami N.、Ohkura N.、Maekawa T.、Takahashi N.、Tohma A.、Izumi K.、Maeda T.、Hosoya A.、Nakamura H.、Tabeta K.、Noiri Y.、Yoshiba K.
    • Journal Title

      Journal of Dental Research

      Volume: 99 Pages: 329-338

    • DOI

      10.1177/0022034519894957

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-19K10126, KAKENHI-PROJECT-19K10146, KAKENHI-PROJECT-19K10171, KAKENHI-PROJECT-18KK0434, KAKENHI-PROJECT-16H05516
  • [Journal Article] Gingival epithelial barrier: regulation by beneficial and harmful microbes2019

    • Author(s)
      Takahashi Naoki、Sulijaya Benso、Yamada-Hara Miki、Tsuzuno Takahiro、Tabeta Koichi、Yamazaki Kazuhisa
    • Journal Title

      Tissue Barriers

      Volume: 7

    • DOI

      10.1080/21688370.2019.1651158

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-19K10126, KAKENHI-PROJECT-19K24139, KAKENHI-PROJECT-18KK0434
  • [Journal Article] Nutrition as Adjunct Therapy in Periodontal Disease Management2019

    • Author(s)
      Sulijaya Benso、Takahashi Naoki、Yamazaki Kyoko、Yamazaki Kazuhisa
    • Journal Title

      Current Oral Health Reports

      Volume: 6 Pages: 61-69

    • DOI

      10.1007/s40496-019-0216-4

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-19K10126, KAKENHI-PROJECT-18KK0434
  • [Journal Article] Antimicrobial function of the polyunsaturated fatty acid KetoC in an experimental model of periodontitis2019

    • Author(s)
      Sulijaya Benso、Yamada‐Hara Miki、Yokoji‐Takeuchi Mai、Matsuda‐Matsukawa Yumi、Yamazaki Kyoko、Matsugishi Aoi、Tsuzuno Takahiro、Sato Keisuke、Aoki‐Nonaka Yukari、Takahashi Naoki、Kishino Shigenobu、Ogawa Jun、Tabeta Koichi、Yamazaki Kazuhisa
    • Journal Title

      Journal of Periodontology

      Volume: 90 Pages: 1470-1480

    • DOI

      10.1002/jper.19-0130

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-19K10126, KAKENHI-PROJECT-19K18990, KAKENHI-PROJECT-19K24139, KAKENHI-PROJECT-18KK0434
  • [Journal Article] Aggregatibacter actinomycetemcomitans induces detachment and death of human gingival epithelial cells and fibroblasts via elastase release following leukotoxin-dependent neutrophil lysis.2019

    • Author(s)
      Hiyoshi Takumi、Domon Hisanori、Maekawa Tomoki、Nagai Kosuke、Tamura Hikaru、Takahashi Naoki、Yonezawa Daisuke、Miyoshi Tomohiro、Yoshida Akihiro、Tabeta Koichi、Terao Yutaka
    • Journal Title

      Microbiol Immunol.

      Volume: 63 Pages: 100-110

    • DOI

      10.1111/1348-0421.12672

    • NAID

      40021899825

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17K17366, KAKENHI-PROJECT-17KK0165, KAKENHI-PROJECT-16H06272, KAKENHI-PROJECT-16K11439, KAKENHI-PROJECT-17K19747, KAKENHI-PROJECT-19K06494, KAKENHI-PROJECT-19K10126, KAKENHI-PROJECT-18KK0434, KAKENHI-PROJECT-18H02974
  • [Journal Article] A peptide derived from rice inhibits alveolar bone resorption via suppression of inflammatory cytokine production.2019

    • Author(s)
      Aoki‐Nonaka Yukari、Tabeta Koichi、Yokoji Mai、Matsugishi Aoi、Matsuda Yumi、Takahashi Naoki、Sulijaya Benso、Domon Hisanori、Terao Yutaka、Taniguchi Masayuki、Yamazaki Kazuhisa
    • Journal Title

      Journal of Periodontology

      Volume: . Pages: 1160-1169

    • DOI

      10.1002/jper.18-0630

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18K17043, KAKENHI-PROJECT-17J40165, KAKENHI-PROJECT-16K15845, KAKENHI-PROJECT-19K10126, KAKENHI-PROJECT-18KK0434, KAKENHI-PROJECT-19H03829
  • [Journal Article] Indirect regulation of PCSK9 gene in inflammatory response by Porphyromonas gingivalis infection2019

    • Author(s)
      Yokoji-Takeuchi M, Tabeta K, Takahashi N, Arimatsu K, Miyazawa H, Matsuda-Matsukawa Y, Sato K, Yamada M, Yamazaki K.
    • Journal Title

      Heliyon

      Volume: 5(1)

    • DOI

      10.1016/j.heliyon.2018.e01111

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-16K11827, KAKENHI-PROJECT-19K10126, KAKENHI-PROJECT-18KK0434
  • [Journal Article] Host modulation therapy using anti-inflammatory and antioxidant agents in periodontitis: A review to a clinical translation2019

    • Author(s)
      Sulijaya Benso、Takahashi Naoki、Yamazaki Kazuhisa
    • Journal Title

      Archives of Oral Biology

      Volume: 105 Pages: 72-80

    • DOI

      10.1016/j.archoralbio.2019.07.002

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-19K10126, KAKENHI-PROJECT-18KK0434
  • [Journal Article] Effect of ingesting yogurt fermented with Lactobacillus delbrueckii ssp. bulgaricus OLL1073R-1 on influenza virus-bound salivary IgA in elderly residents of nursing homes: A randomized controlled trial2019

    • Author(s)
      Yamamoto Y, Saruta J, Takahashi T, To M, Shimizu T, Hayashi T, Morozumi T, Kubota N, Kamata Y, Makino S, Kano H, Hemmi J, Asami Y, Nagai T, Misawa K, Kato S, Tsukinoki K
    • Journal Title

      Acta Odontologica Scandinavica

      Volume: 印刷中

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17K11984
  • [Journal Article] Effect of ingesting yogurt fermented with Lactobacillus delbrueckii ssp. bulgaricus OLL1073R-1 on influenza virus-bound salivary IgA in elderly residents of nursing homes: a randomized controlled trial2019

    • Author(s)
      Yamamoto Y, Saruta J, Takahashi T, To M, Shimizu T, Hayashi T, Morozumi T, Kubota N, Kamata Y, Makino S, Kano H, Hemmi J, Asami Y, Nagai T, Misawa K, Kato S, Tsukinoki K.
    • Journal Title

      Acta Odontol Scand

      Volume: 77(7) Pages: 517-524

    • DOI

      10.1080/00016357.2019.1609697

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-17K11694, KAKENHI-PROJECT-17K11984, KAKENHI-PROJECT-19K10427, KAKENHI-PROJECT-18K17035
  • [Journal Article] β2-Microglobulin and Neutrophil Gelatinase-Associated Lipocalin, Potential Novel Urine Biomarkers in Periodontitis: A Cross-Sectional Study in Japanese2019

    • Author(s)
      Mayuka Nakajima、Michihiro Hosojima、Koichi Tabeta、Sayuri Miyauchi、Miki Yamada-Hara、Naoki Takahashi、Haruna Miyazawa、Yumi Matsuda-Matsukawa、Keisuke Sato、Noriko Sugita、Yasutaka Komatsu、Tomomi Ishikawa、Kazuhiro Akiishi、Kazuhisa Yamazaki、Kiminori Kato、Akihiko Saito、Hiromasa Yoshie
    • Journal Title

      Int J Dent.

      Volume: 2019 Pages: 1-10

    • DOI

      10.1155/2019/1394678

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-18J40011, KAKENHI-PROJECT-16K11827, KAKENHI-PROJECT-18K09572, KAKENHI-PROJECT-17K09104
  • [Journal Article] Increased serum PCSK9, a potential biomarker to screen for periodontitis, and decreased total bilirubin associated with probing depth in a Japanese community survey.2018

    • Author(s)
      Tabeta K.、Hosojima M.、Nakajima M.、Miyauchi S.、Miyazawa H.、Takahashi N.、Matsuda Y.、Sugita N.、Komatsu Y.、Sato K.、Ishikawa T.、Akiishi K.、Yamazaki K.、Kato K.、Saito A.、Yoshie H.
    • Journal Title

      J Periodontal Res.

      Volume: 印刷中 Pages: 446-456

    • DOI

      10.1111/jre.12533

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-15H02578, KAKENHI-PROJECT-15H05052, KAKENHI-PROJECT-17H06700, KAKENHI-PROJECT-17H06701, KAKENHI-PROJECT-17K09104, KAKENHI-PROJECT-16K11827
  • [Journal Article] A bacterial metabolite ameliorates periodontal pathogen-induced gingival epithelial barrier disruption via GPR40 signaling.2018

    • Author(s)
      Yamada M, Takahashi N, Matsuda Y, Sato K, Yokoji M, Sulijaya B, Maekawa T, Ushiki T, Mikami Y, Hayatsu M, Mizutani Y, Kishino S, Ogawa J, Arita M, Tabeta K, Maeda T, Yamazaki K
    • Journal Title

      Sci Rep

      Volume: 8 Pages: 1-12

    • DOI

      10.1038/s41598-018-27408-y

    • NAID

      120006546008

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-17KK0165, KAKENHI-ORGANIZER-15H05897, KAKENHI-PLANNED-15H05898, KAKENHI-PROJECT-18H04067, KAKENHI-PROJECT-16H06272, KAKENHI-PROJECT-17H06701, KAKENHI-PROJECT-16K11827, KAKENHI-PROJECT-17K19747
  • [Journal Article] The anti-inflammatory effect of 10-oxo-trans-11-octadecenoic acid (KetoC) on RAW 264.7 cells stimulated with Porphyromonas gingivalis lipopolysaccharide.2018

    • Author(s)
      Sulijaya B.、Takahashi N.、Yamada M.、Yokoji M.、Sato K.、Aoki-Nonaka Y.、Nakajima T.、Kishino S.、Ogawa J.、Yamazaki K.
    • Journal Title

      J Periodont Res

      Volume: 印刷中 Pages: 777-784

    • DOI

      10.1111/jre.12564

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-15H02441, KAKENHI-PROJECT-18H04067, KAKENHI-PROJECT-16H05554, KAKENHI-PROJECT-16K11827
  • [Journal Article] An ENU-induced splice site mutation of mouse Col1a1 causing recessive osteogenesis imperfecta and revealing a novel splicing rescue2017

    • Author(s)
      Tabeta K, Du X, Arimatsu K, Yokoji M, Takahashi N, Amizuka N, Hasegawa T, Crozat K, Maekawa T, Miyauchi S, Matsuda Y, Ida T, Kaku M, Hoebe K, Ohno K, Yoshie H, Yamazaki K, Moresco EMY, Beutler B
    • Journal Title

      Sci Rep.

      Volume: 7(1) Pages: 0-0

    • DOI

      10.1038/s41598-017-10343-9

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16K11827, KAKENHI-PROJECT-15K15704, KAKENHI-PROJECT-17K19747, KAKENHI-PROJECT-15KK0337, KAKENHI-PROJECT-26293407, KAKENHI-PROJECT-15H02578, KAKENHI-PROJECT-15H04840, KAKENHI-PROJECT-16H06272, KAKENHI-PROJECT-17H06701
  • [Journal Article] Aggravation of collagen-induced arthritis by orally administered Porphyromonas gingivalis through modulation of the gut microbiota and gut immune system2017

    • Author(s)
      Sato K, Takahashi N, Kato T, Matsuda Y, Yokoji M, Yamada M, Nakajima T, Kondo N, Endo N, Yamamoto R, Noiri Y, Ohno H, Yamazaki K
    • Journal Title

      Scientific reports

      Volume: 7(1) Pages: 1-13

    • DOI

      10.1038/s41598-017-07196-7

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16K11827, KAKENHI-PROJECT-15H02578, KAKENHI-PROJECT-15H05021, KAKENHI-PROJECT-16H05554, KAKENHI-PROJECT-17H06701
  • [Journal Article] Neuronal TRPV1 activation regulates alveolar bone resorption by suppressing osteoclastogenesis via CGRP2016

    • Author(s)
      Takahashi N, Matsuda Y, Sato K, de Jong PR, Bertin S, Tabeta K, Yamazaki K
    • Journal Title

      Sci. Rep

      Volume: 6 Pages: 29294-29294

    • DOI

      10.1038/srep29294

    • Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16K11827
  • [Journal Article] The TRPA1 ion channel is expressed in CD4+ T cells and restrains T-cell-mediated colitis through inhibition of TRPV1.2016

    • Author(s)
      Bertin S, Aoki-Nonaka Y, Lee J, de Jong PR, Kim P, Han T, Yu T, To K, Takahashi N, Boland BS, Chang JT, Ho SB, Herdman S, Corr M, Franco A, Sharma S, Dong H, Akopian AN, Raz E
    • Journal Title

      Gut

      Volume: 2015 Pages: 310710-310710

    • DOI

      10.1136/gutjnl-2015-310710

    • Peer Reviewed / Acknowledgement Compliant / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16K11827
  • [Journal Article] Oral Administration of P. gingivalis Induces Dysbiosis of Gut Microbiota and Impaired Barrier Function Leading to Dissemination of Enterobacteria to the Liver.2016

    • Author(s)
      3.Matsuda Y, Kato T, Takahashi N, Nakajima M, Arimatsu K, Minagawa T, Sato K, Ohno H, Yamazaki K.
    • Journal Title

      J. Periodont. Res.

      Volume: 51 Pages: 639-646

    • DOI

      10.1111/jre.12344

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-15H02578, KAKENHI-PROJECT-25463216, KAKENHI-PROJECT-26861808, KAKENHI-PROJECT-16K11827
  • [Journal Article] ERK5 signalling rescues intestinal epithelial turnover and tumour cell proliferation upon ERK1/2 abrogation2016

    • Author(s)
      de Jong PR, Taniguchi K, Harris AR, Bertin S, Takahashi N, Duong J, Campos AD, Powis G, Corr M, Karin M, Raz E
    • Journal Title

      Nat. Commun

      Volume: 17 Pages: 11551-11551

    • DOI

      10.1038/ncomms11551

    • Peer Reviewed / Acknowledgement Compliant / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16K11827
  • [Journal Article] Brazilian propolis mitigates impaired glucose and lipid metabolism in experimental periodontitis in mice.2016

    • Author(s)
      Nakajima M, Arimatsu K, Minagawa T, Matsuda Y, Sato K, Takahashi N, Nakajima T, Yamazaki K.
    • Journal Title

      BMC Complement. Altern. Med.

      Volume: 16 Pages: 329-329

    • DOI

      10.1186/s12906-016-1305-8

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-15K15763, KAKENHI-PROJECT-16K11827
  • [Journal Article] Epithelial TRPV1 signaling accelerates gingival epithelial cell proliferation.2014

    • Author(s)
      Takahashi N, Matsuda Y, Yamada H, Tabeta K, Nakajima T, Murakami S, Yamazaki K
    • Journal Title

      J Dent Res

      Volume: 93(11) Pages: 1141-1147

    • DOI

      10.1177/0022034514552826

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-13J04959, KAKENHI-PROJECT-25463216, KAKENHI-PROJECT-26861808
  • [Presentation] Porphyromonas gingivalis aggravates experimental induced colitis in mice.2020

    • Author(s)
      Tsuzuno T, Takahashi N, Yamada-Hara M, Yokoji-Takeuchi M, Aoki-Nonaka Y, Matsugishi A, Tabeta K, Yamazaki K
    • Organizer
      International Collaborative Symposium on Development of Human Resources in Practical Oral Health and Treatment
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18KK0434
  • [Presentation] Gingival epithelial cells: a possible target for host modulation therapy?2020

    • Author(s)
      Takahashi N
    • Organizer
      Collaborative Symposium on Development of Human Resources in Practical Oral Health and Treatment
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-19K10126
  • [Presentation] Gingival epithelial cells: a possible target for host modulation therapy?2020

    • Author(s)
      Takahashi N
    • Organizer
      International Collaborative Symposium on Development of Human Resources in Practical Oral Health and Treatment
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18KK0434
  • [Presentation] Porphyromonas gingivalis aggravates experimental induced colitis in mice.2020

    • Author(s)
      Tsuzuno T, Takahashi N, Yamada-Hara M, Yokoji-Takeuchi M, Aoki-Nonaka Y, Matsugishi A, Tabeta K, Yamazaki K
    • Organizer
      Collaborative Symposium on Development of Human Resources in Practical Oral Health and Treatment
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-19K10126
  • [Presentation] 実験的腸炎モデルマウスにおけるPorphyromonas gingivalisによる腸炎増悪メカニズムの解析.2019

    • Author(s)
      都野隆博,高橋直紀,竹内麻衣,原 実生,多部田康一,山崎和久
    • Organizer
      第62回秋季日本歯周病学会学術大会
    • Data Source
      KAKENHI-PROJECT-19K10126
  • [Presentation] Dysbiosis of gut microbiome in Japanese patients with periodontitis.2019

    • Author(s)
      Yamazaki K, Sato K, Nakajima T, Muyazawa H, Takahashi N, Yamada-Hara M, Yokoji M, Yamazaki K
    • Organizer
      7th General Session of the IADR
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-19K10126
  • [Presentation] 実験的腸炎モデルマウスにおけるPorphyromonas gingivalisによる腸炎増悪メカニズムの解析.2019

    • Author(s)
      都野隆博,高橋直紀,竹内麻衣,原 実生,多部田康一,山崎和久
    • Organizer
      第62回秋季日本歯周病学会学術大会
    • Data Source
      KAKENHI-PROJECT-18KK0434
  • [Presentation] Neuronal TRPV1 activation prevents alveolar bone resorption via CGRP.2019

    • Author(s)
      Takahashi N
    • Organizer
      97th General Session of the IADR
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-19K10126
  • [Presentation] Porphyromonas gingivalis口腔投与がDSS誘導性実験的腸炎に及ぼす影響の解析.2019

    • Author(s)
      都野隆博,高橋直紀,竹内麻衣,原 実生,中島麻由佳,多部田康一,山崎和久
    • Organizer
      第62回春季日本歯周病学会学術大会
    • Data Source
      KAKENHI-PROJECT-18KK0434
  • [Presentation] Porphyromonas gingivalisが腸管上皮バリア機能へ及ぼす影響の解析.2019

    • Author(s)
      都野隆博,高橋直紀,竹内麻衣,原 実生,中島麻由佳,多部田康一,山崎和久
    • Organizer
      日本歯科保存学会2019年度春季学術大会
    • Data Source
      KAKENHI-PROJECT-19K10126
  • [Presentation] Oral administration of Porphyromonas gingivalis aggravates intestinal inflammation in mice.2019

    • Author(s)
      Tsuzuno T, Takahashi N, Yokoji M, Yamada-Hara M, Nakajima M, Tabeta K, Yamazaki K
    • Organizer
      97th General Session of the IADR
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-19K10126
  • [Presentation] Neuronal TRPV1 activation prevents alveolar bone resorption via CGRP.2019

    • Author(s)
      Takahashi N
    • Organizer
      97th General Session of the IADR
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18KK0434
  • [Presentation] Oral administration of Porphyromonas gingivalis aggravates intestinal inflammation in mice.2019

    • Author(s)
      Tsuzuno T, Takahashi N, Yokoji M, Yamada-Hara M, Nakajima M, Tabeta K, Yamazaki K
    • Organizer
      97th General Session of the IADR
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18KK0434
  • [Presentation] Porphyromonas gingivalisが腸管上皮バリア機能へ及ぼす影響の解析.2019

    • Author(s)
      都野隆博,高橋直紀,竹内麻衣,原 実生,中島麻由佳,多部田康一,山崎和久
    • Organizer
      日本歯科保存学会2019年度春季学術大会
    • Data Source
      KAKENHI-PROJECT-18KK0434
  • [Presentation] A bacterial metabolite prevents P. gingivalis-induced gingival epithelial barrier disruption in mice model2019

    • Author(s)
      Takahashi N, Yamada M, Sulijaya B, Maeda T, Tabeta K, Yamazaki K
    • Organizer
      International Niigata-Taiwan Universities Collaborative Dental Research Symposium 2019
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16K11827
  • [Presentation] Effect of Ingesting Yogurt Fermented with Lactobacillus delbrueckii ssp. bulgaricus OLL1073R-1 on Influenza Virus-Bound Salivary IgA in Elderly People2019

    • Author(s)
      Yamamoto Y, Saruta J, Takahashi T, To M, Shimizu T, Morozumi T, Kubota N, Makino S, Kano H, Tsukinoki K
    • Organizer
      13th International Scientific Conference on Probiotics, Prebiotics, Gut Microbiota and Health
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17K11984
  • [Presentation] Interaction Between Neural and Non-Neuronal Cells in the Pathogenesis of Periodontitis.2019

    • Author(s)
      Takahashi N, Matsuda-Matsukawa Y, Sato K, Maeda T, Yamazaki K, Tabeta K
    • Organizer
      International Collaborative Symposium on Development of Human Resources in Practical Oral Health and Treatment
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16K11827
  • [Presentation] Porphyromonas gingivalis口腔投与がDSS誘導性実験的腸炎に及ぼす影響の解析.2019

    • Author(s)
      都野隆博,高橋直紀,竹内麻衣,原 実生,中島麻由佳,多部田康一,山崎和久
    • Organizer
      第62回春季日本歯周病学会学術大会
    • Data Source
      KAKENHI-PROJECT-19K10126
  • [Presentation] 10-Hydroxy-cis-12-Octadecenoic Acid Ameliorates Gingival Epithelial Barrier Disruption via GPR40-ERK Signaling2018

    • Author(s)
      Takahashi N, Yamada M, Matsuda Y, Sato K, Yokoji M, Sulijaya B, Tabeta K, Nakajima T, Maeda T, Yamazaki K
    • Organizer
      96th General session of the IADR
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16K11827
  • [Presentation] 広汎型重度慢性歯周炎患者において歯周組織再生療法と局所矯正治療により改善を認 めた一症例2018

    • Author(s)
      両角俊哉,保苅崇大,野村 隆,久保田健彦,小松康高,高橋直紀,奥田一博,三辺正人,吉江弘 正
    • Organizer
      第61回春季日本歯周病学会学術大会
    • Data Source
      KAKENHI-PROJECT-17K11984
  • [Presentation] 歯周病と全身疾患の関連メカニズム―腸内細菌叢を介する新たな仮説―2017

    • Author(s)
      高橋直紀
    • Organizer
      第71回日本口腔科学会学術集会
    • Data Source
      KAKENHI-PROJECT-16K11827
  • [Presentation] 歯肉縁下細菌と血清抗体価による慢性歯周炎進行の予知判定:24ヵ月多施設前向きコホート研究2017

    • Author(s)
      両角俊哉,中川種昭,野口和行,原 宜興,西村英紀,梅田 誠,野口俊英,吉成伸夫,沼部幸博, 伊藤公一,和泉雄一,小方頼昌,三邉正人,齋藤 淳,佐藤 聡,高橋慶壮,川浪雅光,花田信弘, 高柴正悟,吉江弘正
    • Organizer
      日本歯科保存学会2017年度春季学術大会
    • Data Source
      KAKENHI-PROJECT-17K11984
  • [Presentation] 歯肉縁下細菌と血清抗体価を用いた慢性歯周炎進行の評価:24ヵ月多施設前向きコホート研究2017

    • Author(s)
      両角俊哉、角田衣理加、野村義明、中川種昭、野口和行、原 宜興、西村英紀、梅田 誠、 野口俊英、吉成伸夫、沼部幸博、伊藤公一、和泉雄一、小方頼昌、三邉正人、齋藤 淳、佐藤 聡、高橋慶壮、川浪雅光、花田信弘、高柴正悟、吉江弘正
    • Organizer
      第60回春季日本歯周病学会学術大会
    • Data Source
      KAKENHI-PROJECT-17K11984
  • [Presentation] Neuronal TRPV1 activation regulates alveolar bone resorption by suppressing osteoclastogenesis via CGRP.2017

    • Author(s)
      Takahashi N
    • Organizer
      International Symposium on Development of Human Resources in Practical Oral Health and Treatment
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16K11827
  • [Presentation] Neuronal TRPV1 activation inhibits alveolar bone resorption via neuropeptide release.2017

    • Author(s)
      Takahashi N, Matsuda Y, Sato K, Tabeta K, Yamazaki K, Maeda T
    • Organizer
      95th General Session & Exhibition of the IADR
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16K11827
  • [Presentation] A novel mechanism linking periodontitis and rheumatoid arthritis.2017

    • Author(s)
      Sato K, Takahashi N, Matsuda Y, Yamada M, Yokoji M, Tabeta K, Nakajima T, Yamazaki K
    • Organizer
      95th General Session & Exhibition of the IADR
    • Place of Presentation
      米国サンフランシスコ
    • Year and Date
      2017-03-22
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16K11827
  • [Presentation] Effect of resveratrol on occlusal trauma-induced bone loss in mice.2017

    • Author(s)
      Matsuda Y, Okui T, Minagawa T, Tabeta K, Takahashi N, Sato K, Yamada M, Yokoji M, Nakajima T, Yamazaki K
    • Organizer
      95th General Session & Exhibition of the IADR
    • Place of Presentation
      米国サンフランシスコ
    • Year and Date
      2017-03-22
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16K11827
  • [Presentation] A bacterial metabolite ameliorates P. gingivalis-induced gingival epithelial barrier disruption.2017

    • Author(s)
      Yamada M, Takahashi N, Matsuda Y, Sato K, Yokoji M, Tabeta K, Nakajima T, Yamazaki K
    • Organizer
      95th General Session & Exhibition of the IADR
    • Place of Presentation
      米国サンフランシスコ
    • Year and Date
      2017-03-22
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16K11827
  • [Presentation] 細菌抗原によるPCSK9産生の誘導機構2016

    • Author(s)
      横地麻衣, 多部田康一, 宮澤春菜, 野中由香莉, 高橋直紀, 松田由実, 佐藤圭祐, 山田実生, 伊藤晴江, 中島貴子, 山崎和久
    • Organizer
      日本歯科保存学会2016年度秋季学術大会
    • Place of Presentation
      キッセイ文化ホール(長野県松本市)
    • Year and Date
      2016-10-28
    • Data Source
      KAKENHI-PROJECT-15H05052
  • [Presentation] Neuronal TRPV1 activation regulates alveolar bone resorption by osteoclasts via CGRP2015

    • Author(s)
      Takahashi N, Matsuda Y, Sato K, Tabeta K, Yamazaki K
    • Organizer
      63nd Annual meeting of JADR
    • Place of Presentation
      福岡国際会議場(福岡県福岡市)
    • Year and Date
      2015-10-30
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26861808
  • [Presentation] Neuronal TRPV1 prevents alveolar bone resorption in experimental periodontitis mice model.2015

    • Author(s)
      Takahashi N, Matsuda Y, Sato K, Yamada H, Tabeta K, Yamazaki K
    • Organizer
      11th Asian Pacific Society of Periodontology Meeting
    • Place of Presentation
      Bali (Indonesia)
    • Year and Date
      2015-10-08
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26861808
  • [Presentation] 歯肉上皮細胞におけるカプサイシン受容体TRPV1の発現および機能解析2014

    • Author(s)
      高橋直紀、松田由実、山田ひとみ、中島貴子、多部田康一、村上伸也、山崎和久
    • Organizer
      日本歯科保存学会2014年度春季学術大会(第140回)
    • Place of Presentation
      大津市
    • Year and Date
      2014-06-19
    • Data Source
      KAKENHI-PROJECT-26861808
  • [Presentation] TRPV1 Signaling Accelerates Cell Proliferation of Gingival Epithelial Cells.

    • Author(s)
      Takahashi N, Matsuda Y, Tabeta K, Yamazaki K
    • Organizer
      92nd General session of the IADR
    • Place of Presentation
      Cape Town
    • Year and Date
      2014-06-25 – 2014-06-28
    • Data Source
      KAKENHI-PROJECT-26861808
  • 1.  KOICHI TABETA (20401763)
    # of Collaborated Projects: 5 results
    # of Collaborated Products: 28 results
  • 2.  寺尾 豊 (50397717)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 2 results
  • 3.  YAMAZAKI Kazuhisa (00182478)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 27 results
  • 4.  野中 由香莉 (40710520)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 2 results
  • 5.  藤本 啓二 (70229045)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 6.  両角 俊哉 (20444151)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 6 results
  • 7.  小松 康高 (40422597)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 1 results
  • 8.  保苅 崇大 (30827621)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 1 results
  • 9.  宮沢 春菜 (50733721)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 10.  谷口 正之 (00163634)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 1 results
  • 11.  片倉 響子 (70423788)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 12.  YAMADA Hitomi
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 13.  MATSUDA Yumi
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 3 results
  • 14.  KATO Kiminori
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 2 results
  • 15.  DOMON Hisanori
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 16.  YAMAMOTO Reiko
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 17.  KISHINO Shigenobu
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 18.  SUGIMOTO Masahiro
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 19.  SUGITA Noriko
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 20.  中島 貴子
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 4 results
  • 21.  加藤 完
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 3 results
  • 22.  加来 賢
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 23.  前川 知樹
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 3 results
  • 24.  大野 博司
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 3 results
  • 25.  大野 欽司
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 26.  有田 誠
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 27.  有田 正規
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 28.  米澤 大輔
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 29.  三好 智博
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 30.  吉田 明弘
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 31.  野杁 由一郎
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 32.  吉羽 永子
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 33.  大倉 直人
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 34.  吉羽 邦彦
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 35.  枝並 直樹
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 36.  細矢 明宏
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 37.  小川 順
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 38.  槻木 恵一
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 39.  高橋 徹
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 40.  猿田 樹理
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 41.  東 雅啓
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results

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