NAKAGAKI Takehiro 中垣岳大

Researcher Number	80722917
Other IDs	https://orcid.org/0000-0003-1960-8326
External Links
Affiliation (Current)	2024: 長崎大学, 医歯薬学総合研究科(医学系), 准教授
Affiliation (based on the past Project Information) *help	2022 – 2024: 長崎大学, 医歯薬学総合研究科(医学系), 准教授 2021: 長崎大学, 医歯薬学総合研究科(医学系), 助教 2017 – 2019: 長崎大学, 医歯薬学総合研究科(医学系), 助教 2015: 長崎大学, 医歯薬学総合研究科(医学系), 客員研究員 2014: 長崎大学, 医歯薬学総合研究科, 助教
Review Section/Research Field	Principal Investigator Neurology / Basic Section 51030:Pathophysiologic neuroscience-related Except Principal Investigator Basic Section 51030:Pathophysiologic neuroscience-related
Keywords	Principal Investigator オートファジー / FK506 / RT-QUIC法 / プリオン / 孤発性クロイツフェルトヤコブ病 / Tacrolimus / 骨髄間葉細胞 / 再生医療 / 間葉系幹細胞 / 骨髄間葉系細胞 / クロイツフェルトヤコブ病 / 神経変性疾患 / プリオン病 … More Except Principal Investigator … More プリオン病 / 試験管内プリオン増幅法 / 神経変性 / FK506 / ミクログリア Less

ヒト孤発性プリオン多様性の検証Principal Investigator
- Principal Investigator
  
  中垣岳大
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 51030:Pathophysiologic neuroscience-related
- Research Institution
  Nagasaki University
プリオン病発症に関わるミクログリア制御機構の解明
- Principal Investigator
  
  西田教行
- Project Period (FY)
  2021 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 51030:Pathophysiologic neuroscience-related
- Research Institution
  Nagasaki University
次世代ヒトプリオン増幅法の構築とヒトプリオン病創薬スクリーニングへの応用
- Principal Investigator
  
  高月英恵
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 51030:Pathophysiologic neuroscience-related
- Research Institution
  University of Miyazaki
Establishment of a multidisciplinary treatment for sporadic Creutzfeldt-Jakob diseasePrincipal Investigator
- Principal Investigator
  
  NAKAGAKI Takehiro
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Neurology
- Research Institution
  Nagasaki University
Establishment of anti prion therapy by autophagy inducersPrincipal Investigator
- Principal Investigator
  
  NAKAGAKI Takehiro
- Project Period (FY)
  2014 – 2015
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Neurology
- Research Institution
  Nagasaki University

All 2024 2023 2022 2021 2020 2019 2018 2017 2015 2014

All Journal Article Presentation Book Patent

[Book] 標準微生物学第15版2024
- Author(s)
  錫谷達夫、松本哲哉【編】　（分担執筆中垣岳大）
- Total Pages
  688
- Publisher
  医学書院
- Data Source
  KAKENHI-PROJECT-21K07276
[Journal Article] Detection of Prions in a Cadaver for Anatomical Practice2022
- Author(s)
  Nakagaki Takehiro、Kaneko Miho、Satoh Katsuya、Murai Kiyohito、Saiki Kazunobu、Matsumoto Gen、Ogami-Takamura Keiko、Ikematsu Kazuya、Akagi Akio、Iwasaki Yasushi、Tsurumoto Toshiyuki、Nishida Noriyuki
- Journal Title
  
  New England Journal of Medicine
  
  Volume: 386 Issue: 23 Pages: 2245-2246
- DOI
  10.1056/nejmc2204116
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K07276, KAKENHI-PROJECT-21K07417, KAKENHI-PROJECT-20K16183, KAKENHI-PLANNED-18H05414, KAKENHI-PUBLICLY-22H04651, KAKENHI-PROJECT-23K21396, KAKENHI-PROJECT-23K24214
[Journal Article] Synthesis and Characterization of Hydroxyethylamino- and Pyridyl-Substituted 2-Vinyl Chromone Derivatives for Detection of Cerebral Abnormal Prion Protein Deposits2022
- Author(s)
  Nakaie Mari、Katayama Fumihiro、Nakagaki Takehiro、Kawasaki Masao、Yoshida Sakura、Toriba Akira、Ogawa Kazuma、Nishida Noriyuki、Nakayama Morio、Fuchigami Takeshi
- Journal Title
  
  Chemical and Pharmaceutical Bulletin
  
  Volume: 70 Issue: 3 Pages: 211-219
- DOI
  10.1248/cpb.c21-00902
- NAID
  130008165517
- ISSN
  0009-2363, 1347-5223
- Year and Date
  2022-03-01
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K22600, KAKENHI-PROJECT-21K07276, KAKENHI-PROJECT-21K19452
[Journal Article] Synthesis and Biological Evaluation of Novel 2-(Benzofuran-2-yl)-chromone Derivatives for In Vivo Imaging of Prion Deposits in the Brain2022
- Author(s)
  Nakaie Mari、Katayama Fumihiro、Nakagaki Takehiro、Yoshida Sakura、Kawasaki Masao、Nishi Kodai、Ogawa Kazuma、Toriba Akira、Nishida Noriyuki、Nakayama Morio、Fuchigami Takeshi
- Journal Title
  
  ACS Infectious Diseases
  
  Volume: 8 Issue: 9 Pages: 1869-1882
- DOI
  10.1021/acsinfecdis.2c00142
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21K07276, KAKENHI-PROJECT-21K19452, KAKENHI-PROJECT-23K21396, KAKENHI-PROJECT-23K24276
[Journal Article] Development of α-Synuclein Real-Time Quaking-Induced Conversion as a Diagnostic Method for α-Synucleinopathies2021
- Author(s)
  Nakagaki Takehiro、Nishida Noriyuki、Satoh Katsuya
- Journal Title
  
  Frontiers in Aging Neuroscience
  
  Volume: 13 Pages: 703984-703984
- DOI
  10.3389/fnagi.2021.703984
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K22600, KAKENHI-PROJECT-21K07276, KAKENHI-PROJECT-23K21396
[Journal Article] Liquid-liquid phase separation of full-length prion protein initiates conformational conversion in vitro2021
- Author(s)
  Hiroya Tange, Daisuke Ishibashi, Takehiro Nakagaki, Yuzuru Taguchi, Yuji O Kamatari, Hiroki Ozawa, Noriyuki Nishida
- Journal Title
  
  Journal of Biological Chemistry
  
  Volume: 296 Pages: 100367-100367
- DOI
  10.1016/j.jbc.2021.100367
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K07844, KAKENHI-PROJECT-19K22600, KAKENHI-PROJECT-20K06390, KAKENHI-PROJECT-21K07276, KAKENHI-PROJECT-20H04285, KAKENHI-PROJECT-23K21396
[Journal Article] Formalin RT-QuIC assay detects prion-seeding activity in formalin-fixed brain samples from sporadic Creutzfeldt?Jakob disease patients2021
- Author(s)
  Dong Thi-Thu-Trang、Akagi Akio、Nonaka Toshiaki、Nakagaki Takehiro、Mihara Ban、Takao Masaki、Iwasaki Yasushi、Nishida Noriyuki、Satoh Katsuya
- Journal Title
  
  Neurobiology of Disease
  
  Volume: 159 Pages: 105504-105504
- DOI
  10.1016/j.nbd.2021.105504
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K22600, KAKENHI-PROJECT-18K06506, KAKENHI-PROJECT-21K07276, KAKENHI-PROJECT-21K07417, KAKENHI-PROJECT-20K16183, KAKENHI-PROJECT-23K21396
[Journal Article] Dextran sulphate inhibits an association of prions with plasma membrane at the early phase of infection2021
- Author(s)
  Takayuki Fuse, Takehiro Nakagaki, Takujiro Homma, Hiroya Tange, Naohiro Yamaguchi, Ryuichiro Atarashi, Daisuke Ishibashi, Noriyuki Nishida
- Journal Title
  
  Neuroscience research
  
  Volume: S0168-0102(21) Pages: 00018-3
- DOI
  10.1016/j.neures.2021.01.004
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K07844, KAKENHI-PROJECT-19K22600, KAKENHI-PROJECT-21K07276, KAKENHI-PROJECT-20H04285, KAKENHI-PROJECT-23K21396
[Journal Article] Prion protein interacts with the metabotropic glutamate receptor 1 and regulates the organization of Ca2+ signaling2020
- Author(s)
  Matsubara Takehiro、Satoh Katsuya、Homma Takujiro、Nakagaki Takehiro、Yamaguchi Naohiro、Atarashi Ryuichiro、Sudo Yuka、Uezono Yasuhito、Ishibashi Daisuke、Nishida Noriyuki
- Journal Title
  
  Biochemical and Biophysical Research Communications
  
  Volume: 525 Issue: 2 Pages: 447-454
- DOI
  10.1016/j.bbrc.2020.02.102
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K07404, KAKENHI-PROJECT-17K16126, KAKENHI-PROJECT-19K07844, KAKENHI-PROJECT-17K09759, KAKENHI-PROJECT-20H04285
[Journal Article] Type I interferon protects neurons from prions in in vivo models2019
- Author(s)
  Ishibashi Daisuke、Homma Takujiro、Nakagaki Takehiro、Fuse Takayuki、Sano Kazunori、Satoh Katsuya、Mori Tsuyoshi、Atarashi Ryuichiro、Nishida Noriyuki
- Journal Title
  
  Brain
  
  Volume: 142 Issue: 4 Pages: 1035-1050
- DOI
  10.1093/brain/awz016
- NAID
  120006987735
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K10022, KAKENHI-PROJECT-17K09759, KAKENHI-PROJECT-19K07844, KAKENHI-PROJECT-17K16126
[Journal Article] Development of Radioiodinated Benzofuran Derivatives for in Vivo Imaging of Prion Deposits in the Brain2019
- Author(s)
  Fuchigami Takeshi、Kawasaki Masao、Koyama Ryusuke、Nakaie Mari、Nakagaki Takehiro、Sano Kazunori、Atarashi Ryuichiro、Yoshida Sakura、Haratake Mamoru、Ono Masahiro、Nishida Noriyuki、Nakayama Morio
- Journal Title
  
  ACS Infectious Diseases
  
  Volume: － Issue: 12 Pages: 2003-2013
- DOI
  10.1021/acsinfecdis.8b00184
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16H05174, KAKENHI-PROJECT-16H05392, KAKENHI-PROJECT-16K15585, KAKENHI-PROJECT-18K07756, KAKENHI-PROJECT-17K16126
[Journal Article] Postmortem Quantitative Analysis of Prion Seeding Activity in the Digestive System2019
- Author(s)
  Satoh K, Fuse T, Nonaka T, Dong T, Takao M, Nakagaki T, Ishibashi D, Taguchi Y, Mihara B, Iwasaki Y, Yoshida M, Nishida N.
- Journal Title
  
  Molecules.
  
  Volume: 24(24) Issue: 24 Pages: 4601-4601
- DOI
  10.3390/molecules24244601
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K09759, KAKENHI-PROJECT-19K07844, KAKENHI-PROJECT-17K16126
[Journal Article] Identification of alprenolol hydrochloride as an anti-prion compound using surface plasmon resonance imaging2018
- Author(s)
  Y. Miyazaki, T. Ishikawa, Y. O. Kamatari, T. Nakagaki, H. Takatsuki, D. Ishibashi, K. Kuwata, N. Nishida*, R. Atarashi
- Journal Title
  
  Mol. Neurobiol
  
  Volume: 印刷中 Issue: 1 Pages: 367-377
- DOI
  10.1007/s12035-018-1088-7
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K00397, KAKENHI-PROJECT-15K07024, KAKENHI-PROJECT-17K16126
[Journal Article] Structure-based drug discovery for combating influenza virus by targeting the PA?PB1 interaction2017
- Author(s)
  Watanabe Ken、Ishikawa Takeshi、Otaki Hiroki、Mizuta Satoshi、Hamada Tsuyoshi、Nakagaki Takehiro、Ishibashi Daisuke、Urata Shuzo、Yasuda Jiro、Tanaka Yoshimasa、Nishida Noriyuki
- Journal Title
  
  Scientific Reports
  
  Volume: 7 Issue: 1 Pages: 9500-9500
- DOI
  10.1038/s41598-017-10021-w
- NAID
  120006987424
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K00397, KAKENHI-PROJECT-16K00853, KAKENHI-PROJECT-16K07042, KAKENHI-PROJECT-17K16126, KAKENHI-PROJECT-16H05840, KAKENHI-PROJECT-16K08844
[Journal Article] Prion-Like Seeding of Misfolded α-Synuclein in the Brains of Dementia with Lewy Body Patients in RT-QUIC2017
- Author(s)
  Sano Kazunori、Atarashi Ryuichiro、Satoh Katsuya、Ishibashi Daisuke、Nakagaki Takehiro、Iwasaki Yasushi、Yoshida Mari、Murayama Shigeo、Mishima Kenichi、Nishida Noriyuki
- Journal Title
  
  Molecular Neurobiology
  
  Volume: - Issue: 5 Pages: 3916-3930
- DOI
  10.1007/s12035-017-0624-1
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K07042, KAKENHI-PROJECT-17K09759, KAKENHI-PROJECT-15K08369, KAKENHI-PROJECT-16H06277, KAKENHI-PROJECT-17K16126
[Journal Article] Strain-Dependent Effect of Macroautophagy on Abnormally Folded Prion Protein Degradation in Infected Neuronal Cells.2015
- Author(s)
  Ishibashi D, Homma T, Nakagaki T, Fuse T, Sano K, Takatsuki H, Atarashi R, Nishida N.
- Journal Title
  
  PLoS One.
  
  Volume: 10 Issue: 9 Pages: 0137958-0137958
- DOI
  10.1371/journal.pone.0137958
- NAID
  120006986825
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15H04269, KAKENHI-PROJECT-25461514, KAKENHI-PROJECT-26860671
[Journal Article] Characterisation of radioiodinated flavonoid derivatives for SPECT imaging of cerebral prion deposits.2015
- Author(s)
  Fuchigami T, Yamashita Y, Kawasaki M, Ogawa A, Haratake M, Atarashi R, Sano K, Nakagaki T, Ubagai K, Ono M, Yoshida S, Nishida N, Nakayama M.
- Journal Title
  
  Sci Rep.
  
  Volume: 5 Issue: 1 Pages: 18440-18440
- DOI
  10.1038/srep18440
- NAID
  120006987233
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-15K09895, KAKENHI-PROJECT-15H04269, KAKENHI-PROJECT-25461514, KAKENHI-PROJECT-26860671
[Journal Article] Ubiquitin-specific protease 14 modulates degradation of cellular prion protein.2015
- Author(s)
  Homma T, Ishibashi D, Nakagaki T, Fuse T, Mori T, Satoh K, Atarashi R, Nishida N.
- Journal Title
  
  Sci Rep.
  
  Volume: 5 Issue: 1 Pages: 11028-11028
- DOI
  10.1038/srep11028
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15H04269, KAKENHI-PROJECT-26860671, KAKENHI-PROJECT-26305030
[Journal Article] Rapid and Quantitative Assay of Amyloid-Seeding Activity in Human Brains Affected with Prion Diseases.2015
- Author(s)
  Takatsuki H, Satoh K, Sano K, Fuse T, Nakagaki T, Mori T, Ishibashi D, Mihara B, Takao M, Iwasaki Y, Yoshida M, Atarashi R, Nishida N.
- Journal Title
  
  PLoS One
  
  Volume: 10 Issue: 6 Pages: 0126930-0126930
- DOI
  10.1371/journal.pone.0126930
- NAID
  120006986998
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K08369, KAKENHI-PROJECT-26430060, KAKENHI-PROJECT-15H04269, KAKENHI-PROJECT-25461514, KAKENHI-PROJECT-26860671, KAKENHI-PROJECT-26305030
[Journal Article] Conformational properties of prion strains can be transmitted to recombinant prion protein fibrils in real-time quaking-induced conversion.2014
- Author(s)
  Sano K, Atarashi R, Ishibashi D, Nakagaki T, Satoh K, Nishida N.
- Journal Title
  
  J Virol
  
  Volume: 88(20) Issue: 20 Pages: 11791-11801
- DOI
  10.1128/jvi.00585-14
- NAID
  120006986372
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23300127, KAKENHI-PROJECT-24591268, KAKENHI-PROJECT-24591482, KAKENHI-PROJECT-25461514, KAKENHI-PROJECT-25640029, KAKENHI-PROJECT-26305030, KAKENHI-PROJECT-26860671
[Journal Article] Persistent prion infection disturbs the function of Oct-1, resulting in the down-regulation of murine interferon regulatory factor-3.2014
- Author(s)
  Homma T, Ishibashi D, Nakagaki T, Fuse T, Sano K, Satoh K, Atarashi R, Nishida N.
- Journal Title
  
  Sci Rep
  
  Volume: 4 Issue: 1 Pages: 6006-6006
- DOI
  10.1038/srep06006
- NAID
  120006986450
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23300127, KAKENHI-PROJECT-24591268, KAKENHI-PROJECT-24591482, KAKENHI-PROJECT-25461514, KAKENHI-PROJECT-25640029, KAKENHI-PROJECT-26305030, KAKENHI-PROJECT-26860671
[Patent] 経皮吸収型貼付剤2022
- Inventor(s)
  中垣岳大、後藤雅宏、西田教行、佐藤克也、小坂秀斗
- Industrial Property Rights Holder
  中垣岳大、後藤雅宏、西田教行、佐藤克也、小坂秀斗
- Industrial Property Rights Type
  特許
- Filing Date
  2022
- Overseas
- Data Source
  KAKENHI-PROJECT-23K21396
[Patent] 経皮吸収型貼付剤2022
- Inventor(s)
  中垣岳大、後藤雅宏、西田教行、佐藤克也、小坂秀斗
- Industrial Property Rights Holder
  中垣岳大、後藤雅宏、西田教行、佐藤克也、小坂秀斗
- Industrial Property Rights Type
  特許
- Filing Date
  2022
- Overseas
- Data Source
  KAKENHI-PROJECT-21K07276
[Presentation] 試験管内アミロイド増幅法を用いたプリオン病未診断例の探索2023
- Author(s)
  中垣岳大
- Organizer
  第47回日本分子生物学会
- Invited
- Data Source
  KAKENHI-PROJECT-21K07276
[Presentation] A preclinical case in cadavers for forensic anatomy2023
- Author(s)
  Takehiro Nakagaki, Miho Kaneko, Akio Akagi, Yasushi Iwasaki, Katsuya Satoh, Kazuya Ikematsu, Noriyuki Nishida.
- Organizer
  PRION 2023
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K07276
[Presentation] Investigation of the effect of the emergence of drug-resistant prion in mice2023
- Author(s)
  Hanae Takatsuki, Morikazu Imamura, Takehiro Nakagaki, Miho Kaneko, Tsuyoshi Mori, Noriyuki Nishida and Ryuichiro Atarashi
- Organizer
  Asian Pacific Prion Symposium 2023 Tokyo
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K07277
[Presentation] An undiagnosed case of prion disease found in donated bodies for anatomical practice of medical students2022
- Author(s)
  Takehiro Nakagaki.
- Organizer
  Asian Pacific Prion Symposium.
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K07276
[Presentation] An undiagnosed case of prion disease found in donated bodies for anatomical practice of medical students2022
- Author(s)
  Takehiro Nakagaki, Miho Kaneko, Akio Akagi, Yasushi Iwasaki, Katsuya Satoh, Noriyuki Nishida.
- Organizer
  PRION2022.
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K07276
[Presentation] 解剖御遺体におけるプリオン病未診断例の探索2022
- Author(s)
  中垣岳大, 金子美穂, 赤木明生, 佐藤克也, 岩崎靖, 西田教行.
- Organizer
  九州微生物フォーラム.
- Data Source
  KAKENHI-PROJECT-21K07276
[Presentation] 解剖実習御遺体のプリオンスクリーニング2022
- Author(s)
  中垣岳大、金子美穂、佐藤克也、赤木明生、岩崎靖、西田教行.
- Organizer
  日本神経感染症学会
- Data Source
  KAKENHI-PROJECT-21K07276
[Presentation] MM1型プリオン多様性の検証2022
- Author(s)
  中垣岳大, 金子美穂, 西田教行
- Organizer
  日本ウイルス学会
- Data Source
  KAKENHI-PROJECT-21K07276
[Presentation] 孤発性プリオン多様性の検証2021
- Author(s)
  中垣岳大、佐藤克也、西田教行
- Organizer
  神経感染症学会
- Data Source
  KAKENHI-PROJECT-21K07276
[Presentation] 炭酸水素カルシウムメゾ構造体を用いたプリオン不活化の検討2019
- Author(s)
  四元鉄、中垣岳大、西田教行
- Organizer
  第56回日本ウイルス学会九州支部会
- Data Source
  KAKENHI-PROJECT-17K16126
[Presentation] 病理組織切片からの高感度異常型プリオンタンパク検出法の開発2019
- Author(s)
  中垣岳大、西田教行
- Organizer
  第56回日本ウイルス学会九州支部会
- Data Source
  KAKENHI-PROJECT-17K16126
[Presentation] Investigation of the effect of dysbiosis caused by Ceftriaxone on the oral infection with mouse adapted BSE.2019
- Author(s)
  Takehiro Nakagaki, Hanae Takatsuki, Elizar Tsvetkov and Noriyuki Nishida
- Organizer
  Asia Pacific Prion Symposium
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K16126
[Presentation] Administration of FK506 prolongs survival of mice with sporadic Creutzfeldt-Jakob disease agent2018
- Author(s)
  Takehiro Nakagaki
- Organizer
  Asia Pacific Prion Symposium 2018
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K16126
[Presentation] 炭酸水素カルシウムメゾ構造体によるプリオン不活化能の検討2018
- Author(s)
  中垣岳大、的場苑子、石橋大輔、西田教行
- Organizer
  第55回ウイルス学会九州支部総会
- Data Source
  KAKENHI-PROJECT-17K16126
[Presentation] The comparison of anti-prion effect of autophagy inducers2015
- Author(s)
  Takehiro Nakagaki
- Organizer
  Asia Pasific Prion Symposium 2015
- Place of Presentation
  石川県金沢市　石川音楽堂
- Year and Date
  2015-09-03
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26860671

1. 西田教行 (40333520)

# of Collaborated Projects: 1 results

# of Collaborated Products: 4 results
2. 高月英恵 (80773978)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
3. ISHIKAWA Takeshi

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
4. ATARASHI Ryuichiro

# of Collaborated Projects: 0 results

# of Collaborated Products: 4 results
5. ISHIBASHI Ishibashi

# of Collaborated Projects: 0 results

# of Collaborated Products: 3 results
6. 佐藤克也

# of Collaborated Projects: 0 results

# of Collaborated Products: 4 results
7. 森剛志

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
8. 淵上剛志

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
9. 中山守雄

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
10. 吉田さくら

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
11. 上園保仁

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
12. 西弘大

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
13. 岩崎靖

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

NAKAGAKI Takehiro 中垣 岳大

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ヒト孤発性プリオン多様性の検証Principal Investigator

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プリオン病発症に関わるミクログリア制御機構の解明

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次世代ヒトプリオン増幅法の構築とヒトプリオン病創薬スクリーニングへの応用

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Establishment of a multidisciplinary treatment for sporadic Creutzfeldt-Jakob diseasePrincipal Investigator

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Establishment of anti prion therapy by autophagy inducersPrincipal Investigator

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[Book] 標準微生物学第15版2024

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[Journal Article] Detection of Prions in a Cadaver for Anatomical Practice2022

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[Journal Article] Synthesis and Characterization of Hydroxyethylamino- and Pyridyl-Substituted 2-Vinyl Chromone Derivatives for Detection of Cerebral Abnormal Prion Protein Deposits2022

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[Journal Article] Synthesis and Biological Evaluation of Novel 2-(Benzofuran-2-yl)-chromone Derivatives for In Vivo Imaging of Prion Deposits in the Brain2022

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[Journal Article] Development of α-Synuclein Real-Time Quaking-Induced Conversion as a Diagnostic Method for α-Synucleinopathies2021

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[Journal Article] Liquid-liquid phase separation of full-length prion protein initiates conformational conversion in vitro2021

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[Journal Article] Formalin RT-QuIC assay detects prion-seeding activity in formalin-fixed brain samples from sporadic Creutzfeldt?Jakob disease patients2021

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[Journal Article] Dextran sulphate inhibits an association of prions with plasma membrane at the early phase of infection2021

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[Journal Article] Prion protein interacts with the metabotropic glutamate receptor 1 and regulates the organization of Ca2+ signaling2020

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NAKAGAKI Takehiro 中垣岳大