Nakamura Takashi 中村高志

Researcher Number	80724179
Other IDs
Affiliation (Current)	2025: 京都府立医科大学, 医学(系)研究科(研究院), 助教
Affiliation (based on the past Project Information) *help	2021 – 2024: 京都府立医科大学, 医学(系)研究科(研究院), 助教 2017: 京都府立医科大学, 医学部附属病院, 研究員 2016: 京都府立医科大学, 医学部附属病院, 専攻医 2015: 京都府立医科大学, 医学部附属病院, 病院助教 2014: 京都府立医科大学, 医学部附属病院, 研究員
Review Section/Research Field	Principal Investigator Basic Section 56050:Otorhinolaryngology-related / Otorhinolaryngology / General anatomy (including histology/embryology) Except Principal Investigator Basic Section 48030:Pharmacology-related
Keywords	Principal Investigator Mid1 / 小脳顆粒細胞 / 内耳有毛細胞 / 遅発性感音難聴 / 先天性サイトメガロウィルス感染症 / 蝸牛オルガノイド / 内耳再生 / 感覚上皮幹細胞 / 内耳オルガノイド培養 / 内耳再生医療 … More / SOX2 / 内耳オルガノイド / Opitz G/BBB症候群 / 脳・神経 / OpitzG/BBB症候群 / Mid2 / mTORC1 / Rac1 / 活性化 / 失調性歩行 / 蝸牛有毛細胞 / Rac / Rac GTPase … More Except Principal Investigator 難聴 / ROS / NADPH oxidase / 後天性難聴 / 活性酸素 / 後天性感音難聴 Less

活性酸素産生酵素NOX3の発現制御機序解明による後天性及び片側性難聴の治療法開発
- Principal Investigator
  
  上山健彦
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 48030:Pharmacology-related
- Research Institution
  Kobe University
Development of a Congenital CMV Infection Model Using Human Cochlear Organoids and Elucidation of the Pathogenesis of Hearing LossPrincipal Investigator
- Principal Investigator
  
  中村高志
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56050:Otorhinolaryngology-related
- Research Institution
  Kyoto Prefectural University of Medicine
Elucidation of acquired SNHL mechanism caused from Nox3-derived ROS and beyond
- Principal Investigator
  
  Ueyama Takehiko
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 48030:Pharmacology-related
- Research Institution
  Kobe University
Identification and expansion of sensory epithelial stem cell from human inner ear organoidPrincipal Investigator
- Principal Investigator
  
  Nakamura Takashi
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56050:Otorhinolaryngology-related
- Research Institution
  Kyoto Prefectural University of Medicine
Pathological analysis of Opitz G/BBB syndromePrincipal Investigator
- Principal Investigator
  
  Nakamura Takashi
- Project Period (FY)
  2016 – 2017
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Otorhinolaryngology
- Research Institution
  Kyoto Prefectural University of Medicine
The function of Rac GTP-ases in inner ear haircellsPrincipal Investigator
- Principal Investigator
  
  Nakamura Takashi
- Project Period (FY)
  2014 – 2015
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  General anatomy (including histology/embryology)
- Research Institution
  Kyoto Prefectural University of Medicine

All 2023 2022 2017 2015

All Journal Article Presentation

[Journal Article] Defining developmental trajectories of prosensory cells in human inner ear organoids at single-cell resolution2023
- Author(s)
  Ueda Yoshitomo、Nakamura Takashi、Nie Jing、Solivais Alexander J.、Hoffman John R.、Daye Becca J.、Hashino Eri
- Journal Title
  
  Development
  
  Volume: 150 Issue: 12
- DOI
  10.1242/dev.201071
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K09638
[Journal Article] Generating high-fidelity cochlear organoids from human pluripotent stem cells2023
- Author(s)
  Moore Stephen T.、Nakamura Takashi、Nie Jing、Solivais Alexander J.、Aristiz?bal-Ram?rez Isabel、Ueda Yoshitomo、Manikandan Mayakannan、Reddy V. Shweta、Romano Daniel R.、Hoffman John R.、Perrin Benjamin J.、Nelson Rick F.、Frolenkov Gregory I.、Chuva de Sousa Lopes Susana M.、Hashino Eri
- Journal Title
  
  Cell Stem Cell
  
  Volume: 30 Issue: 7 Pages: 950-961.e7
- DOI
  10.1016/j.stem.2023.06.006
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K09638
[Journal Article] Dispensable role of Rac1 and Rac3 after cochlear hair cell specification2023
- Author(s)
  Nakamura Takashi, Sakaguchi Hirofumi, Mohri Hiroaki, Ninoyu Yuzuru, Goto Akihiro, Yamaguchi Taro, Hishikawa Yoshitaka, Matsuda Michiyuki, Saito Naoaki, Ueyama Takehiko
- Journal Title
  
  Journal of Molecular Medicine
  
  Volume: 101 Issue: 7 Pages: 843-854
- DOI
  10.1007/s00109-023-02317-4
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K06738, KAKENHI-PUBLICLY-22H05496, KAKENHI-PROJECT-21H02672
[Journal Article] Novel role of Rac-Mid1 signaling in medial cerebellar development.2017
- Author(s)
  Nakamura T, Ueyama T, Ninoyu Y, Sakaguchi H, Choijookhuu N, Hishikawa Y, Kiyonari H, Kohta M, Sakahara M, de Curtis I, Kohmura E, Hisa Y, Aiba A, Saito N.
- Journal Title
  
  Development
  
  Volume: 144 Pages: 1863-1875
- NAID
  120006363303
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K20271
[Presentation] 聴覚・平衡覚機能再生に向けた幹細胞トランスレーショナルリサーチ　ヒトオルガノイドモデルを用いた内耳研究の展望2022
- Author(s)
  中村　高志
- Organizer
  第32回日本耳科総会・学術講演会
- Data Source
  KAKENHI-PROJECT-21K09638
[Presentation] Generation and application of human inner ear organoid containing vestibular and cochlear like hair cells．2022
- Author(s)
  Takashi Nakamura
- Organizer
  4th World Congress on Endoscopic Ear Surgery
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K09638
[Presentation] 内耳有毛細胞と小脳顆粒細胞におけるRac分子種の機能解析2015
- Author(s)
  中村高志
- Organizer
  日本耳科学会学術講演会
- Place of Presentation
  長崎ブリックホール
- Year and Date
  2015-10-23
- Data Source
  KAKENHI-PROJECT-26870498

1. Ueyama Takehiko (80346254)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
2. 坂口博史 (00515223)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
3. 足立直子 (70604510)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
4. HISHIKAWA Yoshitaka

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Nakamura Takashi 中村 高志

Research Projects

Research Products

Co-Researchers

活性酸素産生酵素NOX3の発現制御機序解明による後天性及び片側性難聴の治療法開発

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Development of a Congenital CMV Infection Model Using Human Cochlear Organoids and Elucidation of the Pathogenesis of Hearing LossPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Elucidation of acquired SNHL mechanism caused from Nox3-derived ROS and beyond

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Identification and expansion of sensory epithelial stem cell from human inner ear organoidPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Pathological analysis of Opitz G/BBB syndromePrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

The function of Rac GTP-ases in inner ear haircellsPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Defining developmental trajectories of prosensory cells in human inner ear organoids at single-cell resolution2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Generating high-fidelity cochlear organoids from human pluripotent stem cells2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Dispensable role of Rac1 and Rac3 after cochlear hair cell specification2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Novel role of Rac-Mid1 signaling in medial cerebellar development.2017

Author(s)

Journal Title

NAID

Data Source

[Presentation] 聴覚・平衡覚機能再生に向けた幹細胞トランスレーショナルリサーチ ヒトオルガノイドモデルを用いた内耳研究の展望2022

Author(s)

Organizer

Data Source

[Presentation] Generation and application of human inner ear organoid containing vestibular and cochlear like hair cells．2022

Author(s)

Organizer

Data Source

[Presentation] 内耳有毛細胞と小脳顆粒細胞におけるRac分子種の機能解析2015

Author(s)

Organizer

Place of Presentation

Year and Date

Data Source

Nakamura Takashi 中村高志

[Presentation] 聴覚・平衡覚機能再生に向けた幹細胞トランスレーショナルリサーチ　ヒトオルガノイドモデルを用いた内耳研究の展望2022