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OKAMOTO Naoki  岡本 直樹

ORCIDConnect your ORCID iD *help
Researcher Number 80727488
Affiliation (based on the past Project Information) *help 2016 – 2017: 富山大学, 大学院医学薬学研究部(医学), 研究員
Review Section/Research Field
Principal Investigator
Collagenous pathology/Allergology
Keywords
Principal Investigator
創薬 / 天然薬物 / TLR7 / 自然免疫 / 全身性エリテマトーデス
  • Research Projects

    (1 results)
  • Research Products

    (8 results)
  • Co-Researchers

    (5 People)
  •  The development of therapeutic agents for SLE based on inhibition of innate immune receptor TLR7Principal Investigator

    • Principal Investigator
      OKAMOTO Naoki
    • Project Period (FY)
      2016 – 2017
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      Collagenous pathology/Allergology
    • Research Institution
      University of Toyama

All 2018 2017 2016

All Journal Article Presentation Patent

  • [Journal Article] Funiculosin variants and phosphorylated derivatives promote innate immune responses via the Toll-like receptor 4/myeloid differentiation factor-2 complex2017

    • Author(s)
      Okamoto N, Mizote K, Honda H, Saeki A, Watanabe Y, Yamaguchi-Miyamoto T, Fukui R, Tanimura N, Motoi Y, Akashi-Takamura S, Kato T, Fujishita S, Kimura T, Ohto U, Shimizu T, Hirokawa T, Miyake K, Fukase K, Fujimoto Y, Nagai Y, Takatsu K
    • Journal Title

      Journal of Biological Chemistry

      Volume: 292 Issue: 37 Pages: 15378-15394

    • DOI

      10.1074/jbc.m117.791780

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16K19532, KAKENHI-PLANNED-15H05836, KAKENHI-PUBLICLY-17H05991, KAKENHI-PROJECT-16H01885, KAKENHI-PROJECT-17H02207, KAKENHI-PROJECT-15K07960, KAKENHI-PROJECT-15K08527, KAKENHI-PROJECT-16K19596, KAKENHI-PROJECT-15K09491
  • [Patent] トール様受容体7またはトール様受容体9の活性化阻害剤2016

    • Inventor(s)
      髙津聖志, 長井良憲, 岡本直樹, 小林雄一, 藤下繁人
    • Industrial Property Rights Holder
      髙津聖志, 長井良憲, 岡本直樹, 小林雄一, 藤下繁人
    • Industrial Property Rights Type
      特許
    • Filing Date
      2016-09-16
    • Overseas
    • Data Source
      KAKENHI-PROJECT-16K19596
  • [Presentation] 糖尿病モデルマウスの内臓脂肪組織に対するイソリ クイリチゲニンの抗炎症・抗線維化作用の解析2018

    • Author(s)
      本田裕恵, 渡邉康春, 長井良憲, 松永孝之, 岡本直樹, 平井嘉勝, 髙津聖志
    • Organizer
      日本薬学会第138回年会
    • Data Source
      KAKENHI-PROJECT-16K19596
  • [Presentation] Funiculosin variants and their synthetic derivatives are novel agonists for murine and human TLR4/MD-2 complex: Potential reagents for developing vaccine adjuvants2017

    • Author(s)
      Nagai Y, Okamoto N, Takatsu K
    • Organizer
      Basel Life 2017
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16K19596
  • [Presentation] 新規TLRリガンドを活用した自然免疫増強剤及び炎症抑制剤の開発2017

    • Author(s)
      岡本直樹
    • Organizer
      北陸ライフサイエンスクラスター最終成果報告会
    • Data Source
      KAKENHI-PROJECT-16K19596
  • [Presentation] 新規TLRリガンドを活用した自然免疫増強剤及び炎症抑制剤の開発2017

    • Author(s)
      岡本直樹
    • Organizer
      北陸ライフサイエンスクラスター推進協議会ポスターセッション
    • Place of Presentation
      金沢都ホテル
    • Year and Date
      2017-02-15
    • Data Source
      KAKENHI-PROJECT-16K19596
  • [Presentation] Toll様受容体7を標的とした自己免疫病治療薬の創薬研究2016

    • Author(s)
      岡本直樹
    • Organizer
      第43回研究会フォーラム富山「創薬」
    • Place of Presentation
      ホテルグランテラス富山
    • Year and Date
      2016-05-12
    • Data Source
      KAKENHI-PROJECT-16K19596
  • [Presentation] 免疫難病の治療を目指した天然薬物シーズによる創薬開発2016

    • Author(s)
      髙津聖志, 長井良憲, 岡本直樹
    • Organizer
      北陸技術交流テクノフェア2016
    • Place of Presentation
      福井県産業会館
    • Year and Date
      2016-10-20
    • Data Source
      KAKENHI-PROJECT-16K19596
  • 1.  TAKI Hirofumi (10240780)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 2.  ITO Tomoki (70434826)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 3.  OHTO Umeharu (90451856)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 1 results
  • 4.  NAGAI Yoshinori
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 5.  渡邉 康春
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results

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