Iizuka Mana 飯塚麻菜

… Alternative Names

Iizuka-Koga Mana 飯塚麻菜

小賀麻菜

飯塚麻菜

小賀麻菜(飯塚麻菜) コガマナ

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Researcher Number	80734821
Other IDs
Affiliation (Current)	2025: 東京理科大学, 研究推進機構生命医科学研究所, 助教
Affiliation (based on the past Project Information) *help	2025: 東京理科大学, 研究推進機構生命医科学研究所, 助教 2016 – 2023: 慶應義塾大学, 医学部(信濃町), 特任助教 2018: 慶應義塾大学, 医学部(信濃町), 特別研究員(PD) 2014 – 2015: 筑波大学, 医学医療系, 助教
Review Section/Research Field	Principal Investigator Basic Section 57020:Oral pathobiological science-related / Pathobiological dentistry/Dental radiology / Basic Section 54020:Connective tissue disease and allergy-related / Collagenous pathology/Allergology
Keywords	Principal Investigator T細胞 / シェーグレン症候群 / 自己免疫疾患 / CD4+ T細胞 / 自己抗体 / BCR / 自己反応性T細胞 / 腸内細菌 / 免疫学 / RORγt / 制御性T細胞

シェーグレン症候群の病態形成における自己反応性T細胞と自己抗体の相互作用Principal Investigator
- Principal Investigator
  
  飯塚麻菜
- Project Period (FY)
  2025 – 2027
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 57020:Oral pathobiological science-related
- Research Institution
  Tokyo University of Science
シェーグレン症候群における自己反応性T細胞の活性化因子の解明Principal Investigator
- Principal Investigator
  
  飯塚麻菜
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 57020:Oral pathobiological science-related
- Research Institution
  Keio University
Analysis of the association between pathogenic CD4+T cells and microbiota in sialadenitis like Sjogren's syndrome.Principal Investigator
- Principal Investigator
  
  IIZUKA Mana
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 54020:Connective tissue disease and allergy-related
- Research Institution
  Keio University
Elucidation of the function of pathogenic T cells in Sjogren's syndromePrincipal Investigator
- Principal Investigator
  
  Iizuka-Koga Mana
- Project Period (FY)
  2017 – 2018
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Pathobiological dentistry/Dental radiology
- Research Institution
  Keio University
The analysis of pathogenic CD4+ T cells in mice model of Sjogren's syndromePrincipal Investigator
- Principal Investigator
  
  Iizuka Mana
- Project Period (FY)
  2015 – 2016
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Pathobiological dentistry/Dental radiology
- Research Institution
  Keio University
  University of Tsukuba
シェーグレン症候群における病因CD4+T細胞を標的とした疾患特異的治療戦略の構築Principal Investigator
- Principal Investigator
  
  小賀麻菜(飯塚麻菜)
- Project Period (FY)
  2014
- Research Category
  
  Grant-in-Aid for Research Activity Start-up
- Research Field
  
  Collagenous pathology/Allergology
- Research Institution
  University of Tsukuba

All 2024 2022 2021 2020 2019 2018 2017 2015 2014

All Journal Article Presentation

[Journal Article] Single-Cell Analysis Revealed the Role of CD8+ Effector T Cells in Preventing Cardioprotective Macrophage Differentiation in the Early Phase of Heart Failure2021
- Author(s)
  Komai Kyoko、Ito Minako、Nomura Seitaro、Shichino Shigeyuki、Katoh Manami、Yamada Shintaro、Ko Toshiyuki、Iizuka-Koga Mana、Nakatsukasa Hiroko、Yoshimura Akihiko
- Journal Title
  
  Frontiers in Immunology
  
  Volume: 12 Pages: 763647-763647
- DOI
  10.3389/fimmu.2021.763647
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K08891, KAKENHI-PROJECT-18K15129, KAKENHI-PROJECT-19K17587, KAKENHI-PUBLICLY-21H00432, KAKENHI-PROJECT-21H05044, KAKENHI-PROJECT-21H04821, KAKENHI-PROJECT-21H02719, KAKENHI-PROJECT-19J40137, KAKENHI-PROJECT-20K07541, KAKENHI-PROJECT-21H05045, KAKENHI-PROJECT-19H03649
[Journal Article] Kidney GATA3+ regulatory T cells play roles in the convalescence stage after antibody-mediated renal injury.2020
- Author(s)
  Sakai R, Ito M, Komai K, Iizuka-Koga M, Matsuo K, Nakayama T, Yoshie O, Amano K, Nishimasu H, Nureki O, Kubo M, Yoshimura A.
- Journal Title
  
  Cell Mol Immunol.
  
  Volume: Sep Issue: 5 Pages: 11-11
- DOI
  10.1038/s41423-020-00547-x
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PUBLICLY-19H04817, KAKENHI-PROJECT-17H06175, KAKENHI-PROJECT-19H03491, KAKENHI-PROJECT-19K16618, KAKENHI-PROJECT-19K08891, KAKENHI-PROJECT-19J40137
[Journal Article] T-bet over-expression regulates aryl hydrocarbon receptor-mediated T helper type 17 differentiation through an interferon (IFN)γ-independent pathway.2017
- Author(s)
  Yokosawa M, Kondo Y, Tahara M, Iizuka-Koga M, Segawa S, Kaneko S, Tsuboi H, Yoh K, Takahashi S, Matsumoto I, Sumida T.
- Journal Title
  
  Clin Exp Immunol
  
  Volume: 188 Issue: 1 Pages: 22-35
- DOI
  10.1111/cei.12912
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-16K09917, KAKENHI-PROJECT-17K18092, KAKENHI-PROJECT-16J07704
[Journal Article] RORγt antagonist suppresses M3 muscarinic acetylcholine receptor-induced Sj?gren's syndrome-like sialadenitis2017
- Author(s)
  Tahara M.、Tsuboi H.、Segawa S.、Asashima H.、Iizuka-Koga M.、Hirota T.、Takahashi H.、Kondo Y.、Matsui M.、Matsumoto I.、Sumida T.
- Journal Title
  
  Clinical & Experimental Immunology
  
  Volume: 187 Issue: 2 Pages: 213-224
- DOI
  10.1111/cei.12868
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K18092, KAKENHI-PROJECT-16J07704
[Journal Article] Interleukin-33 produced by M2 macrophages and other immune cells contributes to Th2 immune reaction of IgG4-related disease.2017
- Author(s)
  Furukawa S, Moriyama M, Miyake K, Nakashima H, Tanaka A, Maehara T, Iizuka-Koga M, Tsuboi H, Hayashida JN, Ishiguro N, Yamauchi M, Sumida T, Nakamura S
- Journal Title
  
  Sci Rep
  
  Volume: 7 Issue: 1 Pages: 42413-42413
- DOI
  10.1038/srep42413
- NAID
  120007135019
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16H06388, KAKENHI-PROJECT-15K11075, KAKENHI-PROJECT-17K18092, KAKENHI-PROJECT-26293430, KAKENHI-PROJECT-16J07704, KAKENHI-PROJECT-17H01603, KAKENHI-PROJECT-17H04671
[Journal Article] Functional Analysis of Dendritic Cells Generated from T-iPSCs from CD4+ T Cell Clones of Sj?gren's Syndrome2017
- Author(s)
  Iizuka-Koga Mana、Asashima Hiromitsu、Ando Miki、Lai Chen-Yi、Mochizuki Shinji、Nakanishi Mahito、Nishimura Toshinobu、Tsuboi Hiroto、Hirota Tomoya、Takahashi Hiroyuki、Matsumoto Isao、Otsu Makoto、Sumida Takayuki
- Journal Title
  
  Stem Cell Reports
  
  Volume: 8 Issue: 5 Pages: 1155-1163
- DOI
  10.1016/j.stemcr.2017.04.010
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K09842, KAKENHI-PROJECT-17K09966, KAKENHI-PROJECT-17K18092, KAKENHI-PROJECT-16J07704
[Journal Article] Induction and maintenance of regulatory T cells by transcription factors and epigenetic modifications2017
- Author(s)
  Iizuka-Koga Mana、Nakatsukasa Hiroko、Ito Minako、Akanuma Takashi、Lu Qianjin、Yoshimura Akihiko
- Journal Title
  
  Journal of Autoimmunity
  
  Volume: 83 Pages: 113-121
- DOI
  10.1016/j.jaut.2017.07.002
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K19398, KAKENHI-PROJECT-17K18092, KAKENHI-PROJECT-15J03260, KAKENHI-PROJECT-16J07704
[Journal Article] Suppression of glucose-6-phosphate-isomerase induced arthritis by oral administration of transgenic rice seeds expressing altered peptide ligands of glucose-6-phosphate-isomerase.2017
- Author(s)
  Hirota T, Tsuboi H, Iizuka-Koga M, Takahashi H, Asashima H, Yokosawa M, Kondo Y, Ohta M, Wakasa Y, Matsumoto I, Takaiwa F, Sumida T
- Journal Title
  
  Modern Rheumatology
  
  Volume: 印刷中 Issue: 3 Pages: 457-465
- DOI
  10.1080/14397595.2016.1218598
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K19565, KAKENHI-PROJECT-17K18092, KAKENHI-PROJECT-16J07704
[Journal Article] A crucial role of RORγt in the development of spontaneous Sialadenitis-like Sjögren's syndrome.2015
- Author(s)
  Iizuka Mana
- Journal Title
  
  Journal of Immunology
  
  Volume: 194 Issue: 1 Pages: 56-67
- DOI
  10.4049/jimmunol.1401118
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26893028, KAKENHI-PROJECT-15K20882
[Presentation] Functional analysis of autoreactive T cell and autoantibody participated in the pathogenesis of Sjogren's syndrome2024
- Author(s)
  Mana Iizuka, Satoru Takahashi, Isao Matsumoto, Takayuki Sumida, Akihiko Yoshimura
- Organizer
  第52回日本免疫学会学術集会
- Data Source
  KAKENHI-PROJECT-22K09949
[Presentation] Identification of a novel autoantibody which facilitates T cell-mediated Sjogren’s syndrome like sialadenitis2022
- Author(s)
  Mana Iizuka, Satoru Takahashi, Isao Matsumoto, Takayuki Sumida, Akihiko Yoshimura
- Organizer
  第51回日本免疫学会学術集会
- Data Source
  KAKENHI-PROJECT-22K09949
[Presentation] Identifiedpathogenic autoantibodies to induce the development of sialadenitis2021
- Author(s)
  Mana Iizuka,Satoru Takahashi, Isao Matsumoto,Takayuki Sumida, Akihiko Yoshimura
- Organizer
  第50回日本免疫学会学術集会
- Data Source
  KAKENHI-PROJECT-19K08891
[Presentation] CD4+ T細胞を軸としたシェーグレン症候群の病態形成機序の解明2019
- Author(s)
  飯塚麻菜、高橋智、松本功、住田孝之、吉村昭彦
- Organizer
  第28回日本シェーグレン症候群学会学術集会
- Data Source
  KAKENHI-PROJECT-19K08891
[Presentation] A role of pathogenic CD4+ T cells in the development of organ specific autoimmune disease like Sjogren’s syndrome2019
- Author(s)
  Mana Iizuka, Satoru Takahashi, Isao Matsumoto,Takayuki Sumida, Akihiko Yoshimura
- Organizer
  第48回日本免疫学会学術集会
- Data Source
  KAKENHI-PROJECT-19K08891
[Presentation] シェーグレン症候群の病態形成におけるRORγtの役割2018
- Author(s)
  飯塚　麻菜、高橋　智、松本　功、住田　孝之、吉村　昭彦
- Organizer
  日本インターフェロンサイトカイン学会
- Data Source
  KAKENHI-PROJECT-17K18092
[Presentation] TCR analysis of infiltrated CD4+ T cells in the salivary glands of Sjogren’s syndrome mice model2017
- Author(s)
  Mana Iizuka, Satoru Takahashi, Isao Matsumoto, Takayuki Sumida, Akihiko Yoshimura
- Organizer
  International Cytokine & Interferon Society
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K18092
[Presentation] A pathological role of RORγt in the development of sialadenitis like Sjögren’s syndrome2015
- Author(s)
  Iizuka Mana
- Organizer
  The 13th International Symposium on Sjögren’s Syndrome
- Place of Presentation
  ノルウェー
- Year and Date
  2015-05-20
- Data Source
  KAKENHI-PROJECT-26893028
[Presentation] A pathological role of RORγt in the development of sialadenitis like Sjogren’s syndrome2015
- Author(s)
  M Iizuka, H Tsuboi, H Asashima, T Hirota, H Takahashi, Y Kondo, S Takahashi, I Matsumoto, T Sumida
- Organizer
  International Symposium on Sjogren's Syndrome
- Place of Presentation
  ノルウェー (ベルゲン)
- Year and Date
  2015-05-19
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K20882
[Presentation] A crucial role of Th1, Th17 and Treg cells in mouse model for Sjögren’s syndrome2015
- Author(s)
  Iizuka Mana
- Organizer
  Super-global symposium on Sjogren's syndrome
- Place of Presentation
  北海道
- Year and Date
  2015-02-04
- Invited
- Data Source
  KAKENHI-PROJECT-26893028
[Presentation] RORγt過剰発現によるシェーグレン症候群様唾液腺炎の発症機序2015
- Author(s)
  飯塚　麻菜、坪井　洋人、浅島　弘充、廣田　智哉、高橋　広行、近藤　裕也、高橋　智、松本功、住田孝之
- Organizer
  JCRベーシックリサーチカンファレンス
- Place of Presentation
  東京大学 (東京)
- Year and Date
  2015-10-02
- Data Source
  KAKENHI-PROJECT-15K20882
[Presentation] Enforced RORγt expression in T cells induced spontaneous development of Sjögren’s syndrome like sialadenitis2014
- Author(s)
  Iizuka Mana
- Organizer
  日本免疫学会
- Place of Presentation
  京都
- Year and Date
  2014-12-10
- Data Source
  KAKENHI-PROJECT-26893028
[Presentation] 唾液腺炎発症におけるTh17マスター転写因子RORγtの機能解析2014
- Author(s)
  飯塚　麻菜
- Organizer
  日本シェーグレン症候群学会
- Place of Presentation
  長崎
- Year and Date
  2014-09-12
- Data Source
  KAKENHI-PROJECT-26893028

1. AKANUMA Takashi

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# of Collaborated Products: 1 results
2. 近藤裕也

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# of Collaborated Products: 1 results
3. 三宅健介

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4. 伊藤美菜子

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5. 安藤美樹

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6. 廣田智哉

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Iizuka Mana 飯塚 麻菜

Iizuka-Koga Mana 飯塚 麻菜

小賀麻菜

飯塚麻菜

小賀 麻菜(飯塚麻菜) コガ マナ

Research Projects

Research Products

Co-Researchers

シェーグレン症候群の病態形成における自己反応性T細胞と自己抗体の相互作用Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

シェーグレン症候群における自己反応性T細胞の活性化因子の解明Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Analysis of the association between pathogenic CD4+T cells and microbiota in sialadenitis like Sjogren's syndrome.Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Elucidation of the function of pathogenic T cells in Sjogren's syndromePrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

The analysis of pathogenic CD4+ T cells in mice model of Sjogren's syndromePrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

シェーグレン症候群における病因CD4+T細胞を標的とした疾患特異的治療戦略の構築Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Single-Cell Analysis Revealed the Role of CD8+ Effector T Cells in Preventing Cardioprotective Macrophage Differentiation in the Early Phase of Heart Failure2021

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Kidney GATA3+ regulatory T cells play roles in the convalescence stage after antibody-mediated renal injury.2020

Author(s)

Journal Title

DOI

Data Source

[Journal Article] T-bet over-expression regulates aryl hydrocarbon receptor-mediated T helper type 17 differentiation through an interferon (IFN)γ-independent pathway.2017

Author(s)

Journal Title

DOI

Data Source

[Journal Article] RORγt antagonist suppresses M3 muscarinic acetylcholine receptor-induced Sj?gren's syndrome-like sialadenitis2017

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Interleukin-33 produced by M2 macrophages and other immune cells contributes to Th2 immune reaction of IgG4-related disease.2017

Author(s)

Journal Title

DOI

NAID

Data Source

[Journal Article] Functional Analysis of Dendritic Cells Generated from T-iPSCs from CD4+ T Cell Clones of Sj?gren's Syndrome2017

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Induction and maintenance of regulatory T cells by transcription factors and epigenetic modifications2017

Author(s)

Journal Title

DOI

Data Source

Iizuka Mana 飯塚麻菜

Iizuka-Koga Mana 飯塚麻菜

小賀麻菜(飯塚麻菜) コガマナ