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Takahara Masahiro  高原 政宏

ORCIDConnect your ORCID iD *help
Researcher Number 80738427
Other IDs
Affiliation (Current) 2025: 岡山大学, 医療開発領域, 助教
Affiliation (based on the past Project Information) *help 2023: 岡山大学, 大学病院, 助教
2022: 岡山大学, 医歯薬学域, 助教
2021: 岡山大学, 大学病院, 医員
2020: 岡山大学, 医学部, 客員研究員
2019: 岡山大学, 大学病院, 医員
2018: 岡山大学, 大学病院, 助教
2015 – 2017: 岡山大学, 医学部, 客員研究員
Review Section/Research Field
Principal Investigator
Basic Section 53010:Gastroenterology-related / Immunology
Except Principal Investigator
Basic Section 90130:Medical systems-related / Basic Section 53010:Gastroenterology-related / Gastroenterology
Keywords
Principal Investigator
炎症性腸疾患 / CD4 T cell / IBD / 腸管粘膜CD4T細胞 / 酸化的リン酸化 / ミトコンドリア / CD4 T細胞 / メトホルミン / 腸内細菌叢 / LPCD4T細胞 … More / AMPK / エネルギー代謝 / 腸管粘膜CD4T+細胞 / CD4 + T細胞 / 制御性T細胞 / CD4+T細胞 / CD25 … More
Except Principal Investigator
潰瘍性大腸炎 / 免疫学的便潜血反応 / 在宅自己測定 / セルフマネジメント / 免疫学的便潜血検査 / セントラルメモリーT細胞 / 抗体製剤 / 直腸粘膜リンパ球 / フローサイトメトリー / 在宅自己管理検査システム / 内科 / 細菌 / 腸内細菌叢解析 / 腸内環境 / 腸内細菌叢 / 膵癌 Less
  • Research Projects

    (6 results)
  • Research Products

    (3 results)
  • Co-Researchers

    (7 People)
  •  Construction of a home fecal immunochemical test for self-management in patients with ulcerative colitis

    • Principal Investigator
      平岡 佐規子
    • Project Period (FY)
      2023 – 2026
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 90130:Medical systems-related
    • Research Institution
      Okayama University
  •  潰瘍性大腸炎患者における直腸リンパ球の表面発現に基づいた治療効果予測法の確立

    • Principal Investigator
      岩室 雅也
    • Project Period (FY)
      2022 – 2024
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 53010:Gastroenterology-related
    • Research Institution
      Okayama University
  •  Investigation of the usefulness of home-based measurement of fecal immunochemical test in patients with ulcerative colitis.

    • Principal Investigator
      Hiraoka Sakiko
    • Project Period (FY)
      2020 – 2023
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 90130:Medical systems-related
    • Research Institution
      Okayama University
  •  Development of novel therapeutic agent for inflammatory bowel disease targeting the regulation of CD4 T cell metabolismPrincipal Investigator

    • Principal Investigator
      Takahara Masahiro
    • Project Period (FY)
      2020 – 2023
    • Research Category
      Grant-in-Aid for Early-Career Scientists
    • Review Section
      Basic Section 53010:Gastroenterology-related
    • Research Institution
      Okayama University
  •  Investigating intestinal environments as risks for pancreatico-biliary cancers

    • Principal Investigator
      Takaki Akinobu
    • Project Period (FY)
      2017 – 2019
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Gastroenterology
    • Research Institution
      Okayama University
  •  Can the cell surface marker detected by our new culture system be a therapeutic target for inflammatory bowel disease (IBD)?Principal Investigator

    • Principal Investigator
      Takahara Masahiro
    • Project Period (FY)
      2015 – 2017
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      Immunology
    • Research Institution
      Okayama University

All 2022 2021

All Journal Article Presentation

  • [Journal Article] Metformin ameliorates chronic colitis in a mouse model by regulating. interferon-γ-producing lamina. propria CD4 + T cells through AMPK activation2022

    • Author(s)
      Takahara Masahiro
    • Journal Title

      FASEB

      Volume: Feb;36(2) Issue: 2

    • DOI

      10.1096/fj.202100831rr

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-20K16957, KAKENHI-PROJECT-21K19409, KAKENHI-PROJECT-18H04033
  • [Presentation] エネルギー代謝をターゲットにした炎症性腸疾患治療の可能性2022

    • Author(s)
      高原政宏
    • Organizer
      第108回日本消化器病学会総会
    • Data Source
      KAKENHI-PROJECT-20K16957
  • [Presentation] メトホルミンは腸管粘膜CD4+T細胞のAMPKの活性化を介してIFN-γを制御しマウス慢性腸炎を改善させる2021

    • Author(s)
      高原政宏
    • Organizer
      第58回日本消化器免疫学会総会
    • Data Source
      KAKENHI-PROJECT-20K16957
  • 1.  Hiraoka Sakiko (90397894)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 0 results
  • 2.  Takaki Akinobu (80359885)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 3.  森田 英利 (70257294)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 4.  松本 和幸 (40795027)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 5.  岩室 雅也 (30645403)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 6.  白羽 英則 (40379748)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 7.  井口 俊博 (90975153)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results

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