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SAKAKI HIROTSUGU  榊 宏諭

Researcher Number 80744458
Other IDs
  • ORCIDhttps://orcid.org/0000-0002-2094-686X
Affiliation (based on the past Project Information) *help 2019 – 2020: 山形大学, 医学部, 客員研究員
2016 – 2018: 山形大学, 医学部, 医員
Review Section/Research Field
Principal Investigator
Basic Section 56040:Obstetrics and gynecology-related / Obstetrics and gynecology
Except Principal Investigator
Basic Section 56040:Obstetrics and gynecology-related
Keywords
Principal Investigator
がん幹細胞 / 卵巣癌 / 癌幹細胞 / JNK / メタボローム解析 / 婦人科癌 / 医学 / タキソール / シスプラチン / 抗癌剤 … More / 卵巣がん / メチル化 / ヒストン / JMJD3 / methylation / Histone / GSKJ4 … More
Except Principal Investigator
xenograftモデル / オルガノイド / PDX / アスパラギン代謝経路 / パクリタキセル / PDXオルガノイド / 抗がん剤耐性 / メタボローム解析 / パクリタキセル耐性 / 抗がん剤 / 卵巣癌 Less
  • Research Projects

    (3 results)
  • Research Products

    (9 results)
  • Co-Researchers

    (3 People)
  •  Novel therapeutic development based on metabolomic analysis to overcome the recurrent ovarian cancer with anti-cancer drug resistance

    • Principal Investigator
      Nagase Satoru
    • Project Period (FY)
      2018 – 2020
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 56040:Obstetrics and gynecology-related
    • Research Institution
      Yamagata University
  •  Elucidation of the effect of JNK signal suppression on ovarian cancer stem cell metabolismPrincipal Investigator

    • Principal Investigator
      SAKAKI HIROTSUGU
    • Project Period (FY)
      2018 – 2019
    • Research Category
      Grant-in-Aid for Early-Career Scientists
    • Review Section
      Basic Section 56040:Obstetrics and gynecology-related
    • Research Institution
      Yamagata University
  •  Establishment of novel treatment for ovarian cancer via histone methylation controlPrincipal Investigator

    • Principal Investigator
      SAKAKI HIROTSUGU
    • Project Period (FY)
      2016 – 2017
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      Obstetrics and gynecology
    • Research Institution
      Yamagata University

All 2019 2018 2017 2016

All Journal Article Presentation

  • [Journal Article] Rho-Associated Protein Kinase (ROCK) Inhibitors Inhibit Survivin Expression and Sensitize Pancreatic Cancer Stem Cells to Gemcitabine.2016

    • Author(s)
      Takeda H, Okada M, Suzuki S, Kuramoto K, Sakaki H, Watarai H, Sanomachi T, Seino S, Yoshioka T, Kitanaka C.
    • Journal Title

      Anticancer Res

      Volume: 36(12) Pages: 6311-6318

    • Data Source
      KAKENHI-PROJECT-16K20171
  • [Journal Article] The novel JNK inhibitor AS602801 inhibits cancer stem cells in vitro and in vivo.2016

    • Author(s)
      Okada M, Kuramoto K, Takeda H, Watarai H, Sakaki H, Seino S, Seino M, Suzuki S, Kitanaka C
    • Journal Title

      Oncotarget

      Volume: 7(19) Pages: 27021-32

    • Data Source
      KAKENHI-PROJECT-16K20171
  • [Journal Article] Impact of H3K27 Demethylase Inhibitor GSKJ4 on NSCLC Cells Alone and in Combination with Metformin.2016

    • Author(s)
      Watarai H, Okada M, Kuramoto K, Takeda H, Sakaki H, Suzuki S, Seino S, Oizumi H, Sadahiro M, Kitanaka C.
    • Journal Title

      Anticancer Res.

      Volume: 36(11) Pages: 6083-6092

    • Data Source
      KAKENHI-PROJECT-16K20171
  • [Journal Article] Aripiprazole, an Antipsychotic and Partial Dopamine Agonist, Inhibits Cancer Stem Cells and Reverses Chemoresistance.2016

    • Author(s)
      Suzuki S, Okada M, Kuramoto K, Takeda H, Sakaki H, Watarai H, Sanomachi T, Seino S, Yoshioka T, Kitanaka C.
    • Journal Title

      Anticancer Res.

      Volume: 36(10) Pages: 5153-5161

    • Data Source
      KAKENHI-PROJECT-16K20171
  • [Presentation] Metabolome analysis for discovering new therapeutic target of ovarian cancer cells treated with paclitaxel.2019

    • Author(s)
      eino M, Oota T, Okui Y, Suzuki Y, Sakaki H, Sudo T, Nagase S
    • Organizer
      第71回日本産科婦人科学会
    • Data Source
      KAKENHI-PROJECT-18K09217
  • [Presentation] GSKJ4, a selective jumonji histone H3 lysine27 demethylase inhibitor, targets ovarian cancer stem cells2018

    • Author(s)
      Hirotsugu Sakaki
    • Organizer
      AACR
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16K20171
  • [Presentation] GSKJ4, a selective jumonji H3K27 demethylase inhibitor, targets ovarian cancer stem cells2017

    • Author(s)
      Hirotsugu Sakaki
    • Organizer
      第69回日本産科婦人科学会学術講演会
    • Place of Presentation
      リーガロイヤルホテル広島
    • Year and Date
      2017-04-16
    • Data Source
      KAKENHI-PROJECT-16K20171
  • [Presentation] ヒストン脱メチル化酵素阻害薬GSKJ4を用いた卵巣がん幹細胞標的治療2017

    • Author(s)
      榊 宏諭
    • Organizer
      第65回北日本産科婦人科学会
    • Data Source
      KAKENHI-PROJECT-16K20171
  • [Presentation] GSKJ4, a selective jumonji H3K27 demethylase inhibitor, targets ovarian cancer stem cells2017

    • Author(s)
      Hirotsugu Sakaki
    • Organizer
      The 69th Annual Congress of the Japan Society of Obstetrics and Gynecology
    • Data Source
      KAKENHI-PROJECT-16K20171
  • 1.  Nagase Satoru (00292326)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 1 results
  • 2.  清野 学 (40594320)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 3.  太田 剛 (50375341)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 1 results

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