Hakimi Hassan 晴希生ハッサン

… Alternative Names

ハキミハッサンハキミハッサン

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Researcher Number	80745183
Other IDs	https://orcid.org/0000-0001-6678-7393
External Links
Affiliation (based on the past Project Information) *help	2020 – 2021: 帯広畜産大学, 原虫病研究センター, 特任研究員 2019: 長崎大学, 熱帯医学研究所, 助教 2015: 長崎大学, 熱帯医学研究所, 客員研究員
Review Section/Research Field	Principal Investigator Basic Section 42020:Veterinary medical science-related / Veterinary medical science
Keywords	Principal Investigator バベシア / Cattle / Therapeutic target / Vaccine / Protein export / Surface proteins / 赤血球 / ウシ / Babesia bovis / VESA / バベシア・ボビス / 脳性バベシア症

Functional characterization of Babesia bovis proteins expressed on the surface of infected erythrocytes- Toward identification of novel vaccine and therapeutic candidatesPrincipal Investigator
- Principal Investigator
  
  Hakimi Hassan
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 42020:Veterinary medical science-related
- Research Institution
  Obihiro University of Agriculture and Veterinary Medicine
  Nagasaki University
脳性バベシア症における原虫感染赤血球接着機構の解明Principal Investigator
- Principal Investigator
  
  ハキミハッサン
- Project Period (FY)
  2015
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Veterinary medical science
- Research Institution
  Nagasaki University

All 2022 2021 2020 2019 2016 2015

All Journal Article Presentation

[Journal Article] Distinct effects on the secretion of MTRAP and AMA1 in Plasmodium yoelii following deletion of acylated pleckstrin homology domain-containing protein2022
- Author(s)
  Nattawat Chaiyawong, Takahiro Ishizaki, Hassan Hakimi, Masahito Asada, Kazuhide Yahata, Osamu Kaneko
- Journal Title
  
  Parasitology international
  
  Volume: 86 Pages: 102479-102479
- DOI
  10.1016/j.parint.2021.102479
- NAID
  120007180593
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K15983, KAKENHI-PROJECT-19K07525, KAKENHI-PROJECT-19KK0201, KAKENHI-PROJECT-19H03461, KAKENHI-PROJECT-20K22782
[Journal Article] The impact of calcitriol and estradiol on the SARS-CoV-2 biological activity: a molecular modeling approach2022
- Author(s)
  Alireza Mansouri, Rasoul Kowsar, Mostafa Zakariazadeh, Hassan Hakimi, Akio Miyamoto
- Journal Title
  
  Scientific reports
  
  Volume: 12 Issue: 1 Pages: 717-717
- DOI
  10.1038/s41598-022-04778-y
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K15983
[Journal Article] Recent Advances in Molecular Genetic Tools for Babesia2021
- Author(s)
  Hassan Hakimi, H, Masahito Asada, Shinichiro Kawazu
- Journal Title
  
  Veterinary Sciences
  
  Volume: 8 Issue: 10 Pages: 222-222
- DOI
  10.3390/vetsci8100222
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K15983, KAKENHI-PROJECT-19H03120, KAKENHI-PROJECT-19K06384
[Journal Article] Glycosphingolipid GM3 is localized in both exoplasmic and cytoplasmic leaflets of Plasmodium falciparum malaria parasite plasma membrane2021
- Author(s)
  Shiomi Koudatsu, Tatsunori Masatani, Rikako Konishi, Masahito Asada, Hassan Hakimi, Yuna Kurokawa, Kanna Tomioku, Osamu Kaneko & Akikazu Fujita
- Journal Title
  
  Scientific reports
  
  Volume: 11 Issue: 1 Pages: 14890-14890
- DOI
  10.1038/s41598-021-94037-3
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K15983, KAKENHI-PROJECT-20H03154, KAKENHI-PROJECT-19K22435, KAKENHI-PROJECT-22KJ2527
[Journal Article] cAMP-dependent protein kinase regulates secretion of apical membrane antigen 1 (AMA1) in Plasmodium yoelii2021
- Author(s)
  Takahiro Ishizaki, Masahito Asada, Hassan Hakimi, Nattawat Chaiyawong, Yuto Kegawa, Kazuhide Yahatab, Osamu Kaneko
- Journal Title
  
  Parasitology international
  
  Volume: 85 Pages: 102435-102435
- DOI
  10.1016/j.parint.2021.102435
- NAID
  120007172255
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K15983, KAKENHI-PROJECT-19K07525, KAKENHI-PROJECT-19KK0201, KAKENHI-PROJECT-19H03461
[Journal Article] Isolation of viable Babesia bovis merozoites to study parasite invasion2021
- Author(s)
  Hassan Hakimi, H, Masahito Asada, Takahiro Ishizaki, Shinichiro Kawazu
- Journal Title
  
  Scientific reports
  
  Volume: 11 Issue: 1 Pages: 16959-16959
- DOI
  10.1038/s41598-021-96365-w
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K15983, KAKENHI-PROJECT-19H03120, KAKENHI-PROJECT-19K06384
[Journal Article] A novel Plasmodium yoelii pseudokinase, PypPK1, is involved in erythrocyte invasion and exflagellation center formation2020
- Author(s)
  Ishizaki Takahiro、Chaiyawong Nattawat、Hakimi Hassan、Asada Masahito、Tachibana Mayumi、Ishino Tomoko、Yahata Kazuhide、Kaneko Osamu
- Journal Title
  
  Parasitology International
  
  Volume: 76 Pages: 102056-102056
- DOI
  10.1016/j.parint.2020.102056
- NAID
  120006988309
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K07525, KAKENHI-PROJECT-19KK0201, KAKENHI-PROJECT-17J09408, KAKENHI-PROJECT-19K15983, KAKENHI-PROJECT-19H03461
[Journal Article] Novel Babesia bovis exported proteins that modify properties of infected red blood cells2020
- Author(s)
  Hakimi H, Templeton TJ, Sakaguchi M, Yamagishi J, Miyazaki S, Yahata K, Uchihashi T, Kawazu SI, Kaneko O, Asada M
- Journal Title
  
  PLoS Pathogens
  
  Volume: 16(10) Issue: 10 Pages: e1008917-e1008917
- DOI
  10.1371/journal.ppat.1008917
- NAID
  120006988490
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K06384, KAKENHI-PROJECT-19K07525, KAKENHI-PROJECT-19K15983, KAKENHI-PROJECT-19KK0201, KAKENHI-PUBLICLY-19H05389, KAKENHI-PUBLICLY-20H04669, KAKENHI-PROJECT-18H01837, KAKENHI-PROJECT-18K07088, KAKENHI-PROJECT-18K19258, KAKENHI-PROJECT-16KK0183
[Journal Article] Genome editing of Babesia bovis using the CRISPR/Cas9 system.2019
- Author(s)
  Hakimi, H., Ishizaki, T., Kegawa, Y., Kaneko, O., Kawazu, S., and Asada, M.
- Journal Title
  
  mSphere
  
  Volume: 4(3) Issue: 3
- DOI
  10.1128/msphere.00109-19
- NAID
  120006988459
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K19258, KAKENHI-PROJECT-19K15983, KAKENHI-PROJECT-17J09408, KAKENHI-PROJECT-16K08021, KAKENHI-PROJECT-19H03120
[Journal Article] Transient transfection of Babesia ovis using heterologous promoters2019
- Author(s)
  Rosa C, Asada M, Hakimi H, Domingos A, Pimentel M, Antunes S
- Journal Title
  
  Ticks Tick Borne Dis
  
  Volume: 10(6) Issue: 6 Pages: 101279-101279
- DOI
  10.1016/j.ttbdis.2019.101279
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K06384, KAKENHI-PROJECT-19K15983
[Journal Article] Epidemiology, risk factors, and co-infection of vector-borne pathogens in goats from Sistan and Baluchestan province, Iran2019
- Author(s)
  Hakimi H, Sarani A, Takeda M, Kaneko O, Asada M
- Journal Title
  
  PLoS One
  
  Volume: 14(6) Issue: 6 Pages: e0218609-e0218609
- DOI
  10.1371/journal.pone.0218609
- NAID
  120006987685
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K06384, KAKENHI-PROJECT-19K15983, KAKENHI-PROJECT-16K08021
[Journal Article] Initiated Babesia ovata Sexual Stages under In Vitro Conditions Were Recognized by Anti-CCp2 Antibodies, Showing Changes in the DNA Content by Imaging Flow Cytometry2019
- Author(s)
  Nguyen TT, Dang-Trinh MA, Higuchi L, Mosqueda J, Hakimi H, Asada M, Yamagishi J, Umemiya-Shirafuji R, Kawazu SI
- Journal Title
  
  Pathogens
  
  Volume: 8(3) Issue: 3 Pages: 104-104
- DOI
  10.3390/pathogens8030104
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K06384, KAKENHI-PROJECT-18K19258, KAKENHI-PROJECT-19K15983, KAKENHI-PROJECT-19H03120
[Journal Article] Establishment of transient and stable transfection systems for Babesia ovata2016
- Author(s)
  Hakimi H, Yamagishi J, Kegawa Y, Kaneko O, Kawazu SI, Asada M
- Journal Title
  
  Parasit Vectors
  
  Volume: 9 Issue: 1 Pages: 171-171
- DOI
  10.1186/s13071-016-1439-z
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PLANNED-23117008, KAKENHI-PROJECT-15K18783, KAKENHI-PROJECT-25850199
[Journal Article] Asada M, Yahata K, Hakimi H, Yokoyama N, Igarashi I, Kaneko O, Suarez CE, Kawazu SI. Transfection of Babesia bovis by double selection with WR99210 and Blasticidin-S and its application for functional analysis of thioredoxin peroxidase-12015
- Author(s)
  Asada M, Yahata K, Hakimi H, Yokoyama N, Igarashi I, Kaneko O, Suarez CE, Kawazu SI
- Journal Title
  
  PLOS One
  
  Volume: 10(5) Issue: 5 Pages: e0125993-e0125993
- DOI
  10.1371/journal.pone.0125993
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K08448, KAKENHI-PROJECT-15K14862, KAKENHI-PLANNED-23117008, KAKENHI-PROJECT-15K18783, KAKENHI-PROJECT-25850199, KAKENHI-PUBLICLY-15H00891
[Presentation] Cyclic GMP-dependent protein kinase plays a central role for egress of Babesia bovis2021
- Author(s)
  Hassan Hakimi, Masahito Asada, Shinichiro Kawazu
- Organizer
  The 164th Meeting of the Japanese Society of Veterinary Sciences
- Data Source
  KAKENHI-PROJECT-19K15983
[Presentation] A novel Babesia bovis secreted protein responsible for binding of infected erythrocyte to endothelial cells2021
- Author(s)
  Hassan Hakimi, Miako Sakaguchi, Junya Yamagishi, Shinichiro Kawazu, Osamu Kaneko, Masahito Asada
- Organizer
  The 90th Annual Meeting of the Japanese Society of Parasitology
- Data Source
  KAKENHI-PROJECT-19K15983
[Presentation] The expression of a novel multigene family is correlated with channel activity in Babesia bovis-infected erythrocytes2020
- Author(s)
  Hassan Hakimi, Thomas J Templeton, Miako Sakaguchi, Junya Yamagishi, Kazuhide Yahata, Shinichiro Kawazu, Osamu Kaneko, Masahito Asada
- Organizer
  The 89th Annual Meeting of the Japanese Society of Parasitology
- Data Source
  KAKENHI-PROJECT-19K15983
[Presentation] A novel Babesia bovis secreted protein responsible for binding of infected erythrocyte to endothelial cells2019
- Author(s)
  Hassan Hakimi, Miako Sakaguchi, Junya Yamagishi, Kazuhide Yahata, Osamu Kaneko, Masahito Asada
- Organizer
  The 30th Annual Molecular Parasitology Meeting
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K15983
[Presentation] Establishment a stable transfection system for Babesia ovata and its application for functional gene analysis.2016
- Author(s)
  Hassan Hakimi、山岸潤也、白藤－梅宮梨可、外川裕人、金子修、河津信一郎、麻田正仁
- Organizer
  The 85th Annual Meeting of the Japanese society of Parasitology
- Place of Presentation
  宮崎市民プラザ（宮崎県・宮崎市）
- Year and Date
  2016-03-19
- Data Source
  KAKENHI-PROJECT-15K18783
[Presentation] Establishment of transient and stable transfection system for Babesia ovata.2015
- Author(s)
  Hassan Hakimi、山岸潤也、外川裕人、田中健、金子修、河津信一郎、麻田正仁
- Organizer
  158th Meeting of Japanese Society of Veterinary Sciences
- Place of Presentation
  北里大学（青森県・十和田市）
- Year and Date
  2015-09-07
- Data Source
  KAKENHI-PROJECT-15K18783

1. ASADA Masahito

# of Collaborated Projects: 0 results

# of Collaborated Products: 6 results
2. YAHATA Kazuhide

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
3. KANEKO Osamu

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
4. 河津信一郎

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Hakimi Hassan 晴希生 ハッサン

ハキミ ハッサン ハキミ ハッサン

Research Projects

Research Products

Co-Researchers

Functional characterization of Babesia bovis proteins expressed on the surface of infected erythrocytes- Toward identification of novel vaccine and therapeutic candidatesPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

脳性バベシア症における原虫感染赤血球接着機構の解明Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Distinct effects on the secretion of MTRAP and AMA1 in Plasmodium yoelii following deletion of acylated pleckstrin homology domain-containing protein2022

Author(s)

Journal Title

DOI

NAID

Data Source

[Journal Article] The impact of calcitriol and estradiol on the SARS-CoV-2 biological activity: a molecular modeling approach2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Recent Advances in Molecular Genetic Tools for Babesia2021

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Glycosphingolipid GM3 is localized in both exoplasmic and cytoplasmic leaflets of Plasmodium falciparum malaria parasite plasma membrane2021

Author(s)

Journal Title

DOI

Data Source

[Journal Article] cAMP-dependent protein kinase regulates secretion of apical membrane antigen 1 (AMA1) in Plasmodium yoelii2021

Author(s)

Journal Title

DOI

NAID

Data Source

[Journal Article] Isolation of viable Babesia bovis merozoites to study parasite invasion2021

Author(s)

Journal Title

DOI

Data Source

[Journal Article] A novel Plasmodium yoelii pseudokinase, PypPK1, is involved in erythrocyte invasion and exflagellation center formation2020

Author(s)

Journal Title

DOI

NAID

Data Source

[Journal Article] Novel Babesia bovis exported proteins that modify properties of infected red blood cells2020

Author(s)

Journal Title

DOI

NAID

Data Source

[Journal Article] Genome editing of Babesia bovis using the CRISPR/Cas9 system.2019

Author(s)

Journal Title

DOI

NAID

Data Source

[Journal Article] Transient transfection of Babesia ovis using heterologous promoters2019

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Epidemiology, risk factors, and co-infection of vector-borne pathogens in goats from Sistan and Baluchestan province, Iran2019

Author(s)

Journal Title

DOI

NAID

Data Source

[Journal Article] Initiated Babesia ovata Sexual Stages under In Vitro Conditions Were Recognized by Anti-CCp2 Antibodies, Showing Changes in the DNA Content by Imaging Flow Cytometry2019

Author(s)

Hakimi Hassan 晴希生ハッサン

ハキミハッサンハキミハッサン