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SHINOHARA Tamao  篠原 珠緒

ORCIDConnect your ORCID iD *help
Researcher Number 80747452
Affiliation (Current) 2025: 山梨大学, 大学院総合研究部, 医学研究員
Affiliation (based on the past Project Information) *help 2017 – 2022: 山梨大学, 大学院総合研究部, 医学研究員
Review Section/Research Field
Principal Investigator
Basic Section 52050:Embryonic medicine and pediatrics-related
Except Principal Investigator
Basic Section 52050:Embryonic medicine and pediatrics-related / Pediatrics
Keywords
Principal Investigator
血液悪性腫瘍 / 遺伝子メチル化 / 小児急性リンパ性白血病 / 急性白血病 / メチル化 / ALL / MRD / 微小残存病変 / 小児急性白血病
Except Principal Investigator
ゲノム編集 … More / 薬剤感受性 / 急性リンパ性白血病 / がんゲノム / 個別化治療 / 難治性 / 薬剤耐性 / 遺伝子多型 / 白血病 / 一塩基多型 / 遺伝子変異 / 化学療法 Less
  • Research Projects

    (3 results)
  • Research Products

    (17 results)
  • Co-Researchers

    (16 People)
  •  Integrated study aiming at development of precision medicine for poor prognostic acute lymphoblastic leukemia

    • Principal Investigator
      Inukai Takeshi
    • Project Period (FY)
      2019 – 2021
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Review Section
      Basic Section 52050:Embryonic medicine and pediatrics-related
    • Research Institution
      University of Yamanashi
  •  Application of methylation rate in acute childhood leukemia to microscopic residual disease analysis.Principal Investigator

    • Principal Investigator
      Shinohara Tamao
    • Project Period (FY)
      2018 – 2022
    • Research Category
      Grant-in-Aid for Early-Career Scientists
    • Review Section
      Basic Section 52050:Embryonic medicine and pediatrics-related
    • Research Institution
      University of Yamanashi
  •  Establishment of ALL cell line bank to identify genetic factors involving in drug-sensitivity for future precision medicine

    • Principal Investigator
      INUKAI Takeshi
    • Project Period (FY)
      2015 – 2017
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Pediatrics
    • Research Institution
      University of Yamanashi

All 2022 2021 2020 2019 2018 2017 2016 2015

All Journal Article Presentation

  • [Journal Article] Successful treatment of intractable gastrointestinal tract graft-vs-host disease with oral beclomethasone dipropionate in pediatric and young adult patients2022

    • Author(s)
      Akahane Koshi、Watanabe Atsushi、Somazu Shinpei、Harama Daisuke、Shinohara Tamao、Kasai Shin、Oshiro Hiroko、Goi Kumiko、Hasuda Norio、Ozawa Chihiro、Sugita Kanji、Inukai Takeshi
    • Journal Title

      Medicine

      Volume: 101 Issue: 11

    • DOI

      10.1097/md.0000000000029054

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-19H03615
  • [Journal Article] Association of allele-specific methylation of the <i>ASNS</i> gene with asparaginase sensitivity and prognosis in T-ALL2022

    • Author(s)
      Akahane Koshi、Kimura Shunsuke、Miyake Kunio、Watanabe Atsushi、Kagami Keiko、Yoshimura Kentaro、Shinohara Tamao、Harama Daisuke、Kasai Shin、Goi Kumiko、Kawai Tomoko、Hata Kenichiro、Kiyokawa Nobutaka、Koh Katsuyoshi、他7名
    • Journal Title

      Blood Advances

      Volume: 6 Issue: 1 Pages: 212-224

    • DOI

      10.1182/bloodadvances.2021004271

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-19K07728, KAKENHI-PROJECT-20K21707, KAKENHI-PROJECT-19H03615, KAKENHI-PROJECT-20H03928, KAKENHI-PROJECT-20H00528, KAKENHI-PROJECT-21K19405
  • [Journal Article] NUDT15 polymorphism and NT5C2 and PRPS1 mutations influence thiopurine sensitivity in acute lymphoblastic leukaemia cells2021

    • Author(s)
      Somazu S, Tanaka Y, Tamai M, Watanabe A, Kagami K, Abe M, Harama D, Shinohara T, Akahane K, Goi K, Sugita K, Moriyama T, Yang J, Goto H, Minegishi M, Iwamoto S,?Takita J, Inukai T
    • Journal Title

      J Cell Mol Med

      Volume: 25 Issue: 22 Pages: 10521-10533

    • DOI

      10.1111/jcmm.16981

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-20H00528, KAKENHI-PROJECT-19H03615, KAKENHI-PROJECT-21K19405
  • [Journal Article] Association of aberrant ASNS imprinting with asparaginase sensitivity and chromosomal abnormality in childhood BCP-ALL2020

    • Author(s)
      Atsushi Watanabe, Kunio Miyake, Jessica Nordlund, Ann-Christine Syvanen, Louise van der Weyden, Hiroaki Honda, Norimasa Yamasaki, Akiko Nagamachi, Toshiya Inaba, Tomokatsu Ikawa, Kevin Y Urayama, Nobutaka Kiyokawa, Akira Ohara, Shunsuke Kimura, Yasuo Kubota, Junko Takita, Hiroaki Goto, Kimiyoshi Sakaguchi, et al.
    • Journal Title

      Blood

      Volume: 136 Issue: 20 Pages: 2319-2333

    • DOI

      10.1182/blood.2019004090

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-19K08318, KAKENHI-PROJECT-19K22546, KAKENHI-PROJECT-20K21707, KAKENHI-PROJECT-19KK0222, KAKENHI-PROJECT-18H02838, KAKENHI-PROJECT-19H03615, KAKENHI-PROJECT-19H03693, KAKENHI-PROJECT-20H03928, KAKENHI-PROJECT-18K08357, KAKENHI-PROJECT-20H00528
  • [Journal Article] Association of relapse-linked ARID5B single nucleotide polymorphisms with drug resistance in B-cell precursor acute lymphoblastic leukemia cell lines.2020

    • Author(s)
      Tamai M, Huang M, Kagami K, Abe M, Somazu S, Shinohara T, Harama D, Watanabe A, Akahane K, Goi K, Sugita K, Goto H, Minegishi M, Iwamoto S, Inukai T.
    • Journal Title

      Cancer Cell Int

      Volume: 20 Issue: 1 Pages: 434-434

    • DOI

      10.1186/s12935-020-01524-0

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-19H03615
  • [Journal Article] Inherited genetic variants associated with glucocorticoid sensitivity in leukaemia cells.2020

    • Author(s)
      Shinohara T, Urayama KY, Watanabe A, Akahane K, Goi K, Huang M, Kagami K, Abe M, Sugita K, Okada Y, Goto H, Minegishi M, Iwamoto S, Inukai T.
    • Journal Title

      J Cell Mol Med

      Volume: 24 Issue: 22 Pages: 12920-12932

    • DOI

      10.1111/jcmm.15882

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-19H03615
  • [Journal Article] High ENT1 and DCK gene expression levels are a potential biomarker to predict favorable response to nelarabine therapy in T-cell acute lymphoblastic leukemia.2019

    • Author(s)
      Akahane K, Murakami Y, Kagami K, Abe M, Harama D, Shinohara T, Watanabe A, Goi K, Nishi R, Yamauchi T, Kimura S, Takita J, Look AT, Minegishi M, Sugita K, Inukai T.
    • Journal Title

      Hematol Oncol.

      Volume: 37 Issue: 4 Pages: 516-519

    • DOI

      10.1002/hon.2654

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18K07294, KAKENHI-PROJECT-17H04224, KAKENHI-PROJECT-19H03615, KAKENHI-PROJECT-18K19467
  • [Journal Article] Resistance of t(17;19)-acute lymphoblastic leukemia cell lines to multiagents in induction therapy.2019

    • Author(s)
      Watanabe A, Inukai T, Kagami K, Abe M, Takagi M, Fukushima T, Fukushima H, Nanmoku T, Terui K, Ito T, Toki T, Ito E, Fujimura J, Goto H, Endo M, Look T, Kamps M, Minegishi M, Takita J, Inaba T, Takahashi H, Ohara A, Harama D, Shinohara T, Somazu S, Oshiro H, Akahane K, Goi K, Sugita K.
    • Journal Title

      Cancer Med.

      Volume: 7 Issue: 11 Pages: 5274-5288

    • DOI

      10.1002/cam4.2356

    • NAID

      120007159553

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18H04039, KAKENHI-PROJECT-17H04224, KAKENHI-PROJECT-18H02838, KAKENHI-PROJECT-19H03615, KAKENHI-PROJECT-18K19467
  • [Journal Article] Splicing variant profiles and single nucleotide polymorphisms of the glucocorticoid receptor gene in relation to glucocorticoid sensitivity of B-cell precursor acute lymphoblastic leukaemia.2018

    • Author(s)
      Huang M, Inukai T, Kagami K, Abe M, Shinohara T, Watanabe A, Somazu S, Oshiro H, Goi K, Goto H, Minegishi M, Iwamoto S, Urayama KY, Sugita K.
    • Journal Title

      Hematol Oncol.

      Volume: 36(1) Issue: 1 Pages: 245-251

    • DOI

      10.1002/hon.2471

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-15K09645
  • [Journal Article] Anti-leukemic activity of bortezomib and carfilzomib on B-cell precursor ALL with IKZF1 deletion.2017

    • Author(s)
      Takahashi K, Inukai T, Imamura T, Yano M, , Nemoto A, Sato H, Huang M, Abe M, Kagami K, Shinohara T, Watanabe A, Somazu S, Oshiro H, Akahane K, Goi K, Kikuchi J, Furukawa Y, Goto H, Minegishi M, Iwamoto S, Sugita K.
    • Journal Title

      PLoS One

      Volume: 12 Issue: 12 Pages: e0188680-e0188680

    • DOI

      10.1371/journal.pone.0188680

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17K09937, KAKENHI-PROJECT-15K09645
  • [Journal Article] Lack of association between deletion polymorphism of BIM gene and in vitro drug sensitivity in B-cell precursor acute lymphoblastic leukemia2017

    • Author(s)
      Huang Meixian、Miyake Kunio、Kagami Keiko、Abe Masako、Shinohara Tamao、Watanabe Atsushi、Somazu Shinpei、Oshiro Hiroko、Goi Kumiko、Goto Hiroaki、Minegishi Masayoshi、Iwamoto Shotaro、Kiyokawa Nobutaka、Sugita Kanji、Inukai Takeshi
    • Journal Title

      Leukemia Research

      Volume: 60 Pages: 24-30

    • DOI

      10.1016/j.leukres.2017.06.003

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-15K09592, KAKENHI-PROJECT-15K09645
  • [Presentation] B 前駆細胞型 ALL 細胞株の Ara-C 感受性における DCK遺伝子多型と変異の意義2017

    • Author(s)
      篠原珠緒, 犬飼岳史, 渡邊敦, 大城浩子, 赤羽弘資, 合井久美子, 黄媚賢, 阿部正子, 加賀美恵子, 後藤裕明, 峰岸正好, 岩本彰太郎, 杉田完爾
    • Organizer
      第59回日本小児血液がん学会
    • Data Source
      KAKENHI-PROJECT-15K09645
  • [Presentation] B前駆細胞型ALL細胞株の薬剤感受性におけるCASP8遺伝子のins/del多型の意義2016

    • Author(s)
      篠原 珠緒, 犬飼 岳史, 渡邊 敦, 大城 浩子, 赤羽 弘資, 合井 久美子, 黄 媚賢, 阿部 正子, 加賀美 恵子, 後藤 裕明, 峰岸 正好, 岩本 彰太郎, 杉田 完爾
    • Organizer
      日本小児血液がん学会
    • Place of Presentation
      品川プリンスホテル(東京都品川区)
    • Year and Date
      2016-12-15
    • Data Source
      KAKENHI-PROJECT-15K09645
  • [Presentation] Association of GSTM1 and GSTT1 deletion polymorphisms with MTX-sensitivity of BCP-ALL2015

    • Author(s)
      篠原 珠緒, 犬飼 岳史, 渡邊 敦, 杣津 晋平, 大城 浩子, 合井 久美子, 黄 媚賢, 阿部 正子, 加賀美 恵子, 後藤 裕明, 峯岸 正好, 岩本 彰太郎, 阿部 洋, 杉田 完爾
    • Organizer
      日本小児血液がん学会
    • Place of Presentation
      山梨県甲府市
    • Year and Date
      2015-11-27
    • Data Source
      KAKENHI-PROJECT-15K09645
  • [Presentation] Association of germline polymorphisms in the ARID5B gene with its gene expression level and chemoresistance of BCP-ALL2015

    • Author(s)
      玉井 望雅, 犬飼 岳史, 黄 媚賢, 篠原 珠緒, 渡邊 敦, 杣津 晋平, 大城 浩子, 古市 嘉行, 合井 久美子, 阿部 正子, 加賀美 恵子, 後藤 裕明, 峯岸 正好, 岩本 彰太郎, Kevin Urayama , 杉田 完爾
    • Organizer
      日本小児血液がん学会
    • Place of Presentation
      山梨県甲府市
    • Year and Date
      2015-11-27
    • Data Source
      KAKENHI-PROJECT-15K09645
  • [Presentation] 白血病細胞株を用いた小児ALLにおける抗がん剤感受性解析システムの確立2015

    • Author(s)
      犬飼 岳史, 黄 媚賢, 渡邊 敦, 杣津 晋平, 篠原 珠緒, 合井 久美子, 加賀美 恵子, 阿部 正子, 後藤 裕明, 杉田 完爾
    • Organizer
      日本小児科学会
    • Place of Presentation
      大阪府大阪市
    • Year and Date
      2015-04-17
    • Data Source
      KAKENHI-PROJECT-15K09645
  • [Presentation] Association of receptor isoform profiling and SNP typing of glucocorticoid(GC) with GC-sensitivity of BCP-ALL2015

    • Author(s)
      黄 媚賢, 犬飼 岳史, 加賀美 恵子, 阿部 正子, 篠原 珠緒, 渡辺 敦, 杣津 晋平, 大城 浩子, 合井 久美子, 後藤 裕明, 峯岸 正好, 岩本 彰太郎, Kevin Urayama, 杉田 完爾
    • Organizer
      日本小児血液がん学会
    • Place of Presentation
      山梨県甲府市
    • Year and Date
      2015-11-27
    • Data Source
      KAKENHI-PROJECT-15K09645
  • 1.  INUKAI Takeshi (30293450)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 10 results
  • 2.  WATANABE Atsushi (30610498)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 9 results
  • 3.  原間 大輔 (10774078)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 2 results
  • 4.  大城 浩子 (50377537)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 5.  合井 久美子 (70324192)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 3 results
  • 6.  赤羽 弘資 (90377531)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 3 results
  • 7.  YAMAUCHI Takahiro
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 8.  MIYAKE Kunio
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 9.  菊池 次郎
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 10.  坂口 公祥
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 11.  伊藤 悦朗
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 12.  照井 君典
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 13.  土岐 力
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 14.  本名 浩子
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 15.  吉村 健太郎
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 16.  滝田 順子
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results

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