Eshima Hiroaki 江島弘晃

… Alternative Names

江島弘晃エシマヒロアキ

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Researcher Number	80759259
Other IDs
Affiliation (Current)	2025: 長崎国際大学, 人間社会学部, 講師
Affiliation (based on the past Project Information) *help	2025: 長崎国際大学, 人間社会学部, 講師 2021 – 2023: 長崎国際大学, 人間社会学部, 講師 2016: 順天堂大学, 医学(系)研究科(研究院), 博士研究員 2015: 順天堂大学, 医学(系)研究科(研究院), 研究員
Review Section/Research Field	Principal Investigator Basic Section 59040:Nutrition science and health science-related / Basic Section 59020:Sports sciences-related / 0909:Sports sciences, physical education, health sciences, and related fields / Applied health science
Keywords	Principal Investigator 骨格筋 / 治療法 / 筋力 / 糖尿病 / 肥満 / カルシウム / 細胞死 / 過酸化脂質 / サルコペニア / 活性酸素 / カルシウムイオン / 筋収縮

糖尿病性筋萎縮とサルコペニアに共通するリン脂質過酸化の役割解明と治療法の開発Principal Investigator
- Principal Investigator
  
  江島弘晃
- Project Period (FY)
  2024 – 2028
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 59040:Nutrition science and health science-related
- Research Institution
  Nagasaki International University
2型糖尿病の筋力低下を防止する骨格筋ミトコンドリアの新たな制御機構の解明Principal Investigator
- Principal Investigator
  
  江島弘晃
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 59020:Sports sciences-related
- Research Institution
  Nagasaki International University
Development of therapies for sarcopenia focusing on novel cell death mechanismsPrincipal Investigator
- Principal Investigator
  
  Eshima Hiroaki
- Project Period (FY)
  2021 – 2022
- Research Category
  
  Grant-in-Aid for Research Activity Start-up
- Review Section
  
  0909:Sports sciences, physical education, health sciences, and related fields
- Research Institution
  Nagasaki International University
糖尿病による筋機能低下の分子メカニズムの解明Principal Investigator
- Principal Investigator
  
  江島弘晃
- Project Period (FY)
  2015 – 2016
- Research Category
  
  Grant-in-Aid for Research Activity Start-up
- Research Field
  
  Applied health science
- Research Institution
  Juntendo University

All 2024 2023 2022 2021 2016 2015

All Journal Article Presentation Book

[Book] 7章-3 運動生理学から身体不活動の生理・分子生物学へ. エビデンスに基づく身体活動の科学（熊谷秋三, 田中茂穂, 藤井宣晴編集）2016
- Author(s)
  江島弘晃、田村好史
- Total Pages
  300
- Publisher
  杏林書院
- Data Source
  KAKENHI-PROJECT-15H06597
[Journal Article] Sedentary behavior in mice induces metabolic inflexibility by suppressing skeletal muscle pyruvate metabolism.2024
- Author(s)
  Siripoksup P, Cao G, Cluntun AA, Maschek JA, Pearce Q, Lang MJ, Jeong MY, Eshima H, Ferrara PJ, Opurum PC, Mahmassani ZS, Peterlin AD, Watanabe S, Walsh MA, Taylor EB, Cox JE, Drummond MJ, Rutter J, Funai K.
- Journal Title
  
  J Clin Invest.
  
  Volume: 1 Issue: 11
- DOI
  10.1172/jci167371
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K17745
[Journal Article] Lipid hydroperoxides promote sarcopenia through carbonyl stress2023
- Author(s)
  Eshima Hiroaki、Shahtout Justin L、Siripoksup Piyarat、Funai Katsuhiko et al.
- Journal Title
  
  eLife
  
  Volume: 12
- DOI
  10.7554/elife.85289
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K17745, KAKENHI-PROJECT-21K21271
[Journal Article] A chronic high‐fat diet does not exacerbate muscle atrophy in fast‐twitch skeletal muscle of aged mice2023
- Author(s)
  Tagawa Tsutomu、Eshima Hiroaki、Kakehi Saori、Kawamori Ryuzo、Watada Hirotaka、Tamura Yoshifumi
- Journal Title
  
  Experimental Physiology
  
  Volume: 1 Issue: 7 Pages: 1-1
- DOI
  10.1113/ep091106
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22K17745, KAKENHI-PROJECT-21K11684
[Journal Article] Inhibition of skeletal muscle Lands cycle ameliorates weakness induced by physical inactivity.2023
- Author(s)
  Shahtout JL, Eshima H, Ferrara PJ, Maschek JA, Cox JE, Drummond MJ, Funai K.
- Journal Title
  
  bioRxiv
  
  Volume: 15(1) Issue: 1 Pages: 319-330
- DOI
  10.1002/jcsm.13406
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K17745
[Journal Article] Impaired fatigue resistance, sarcoplasmic reticulum function, and mitochondrial activity in soleus muscle of db/db mice2022
- Author(s)
  Yamamoto H, Eshima H, Kakehi S, Kawamori R, Watada H, Tamura Y.
- Journal Title
  
  Physiol Rep.
  
  Volume: 10 Issue: 18
- DOI
  10.14814/phy2.15478
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K11684, KAKENHI-PROJECT-22K17745, KAKENHI-PROJECT-21K21271
[Journal Article] Metformin and leucine increase satellite cells and collagen remodeling during disuse and recovery in aged muscle2021
- Author(s)
  Petrocelli Jonathan J.、Mahmassani Ziad S.、Fix Dennis K.、Montgomery Jessie A.、Reidy Paul T.、McKenzie Alec I.、Hart Naomi M.、Ferrara Patrick J.、Kelley Joshua J.、Eshima Hiroaki、Funai Katsuhiko、Drummond Micah J.
- Journal Title
  
  The FASEB Journal
  
  Volume: 35 Issue: 9
- DOI
  10.1096/fj.202100883r
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21K21271
[Journal Article] Influence of Obesity and Type 2 Diabetes on Calcium Handling by Skeletal Muscle: Spotlight on the Sarcoplasmic Reticulum and Mitochondria2021
- Author(s)
  Eshima Hiroaki
- Journal Title
  
  Frontiers in Physiology
  
  Volume: 12 Pages: 758316-758316
- DOI
  10.3389/fphys.2021.758316
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21K21271
[Journal Article] Low lysophosphatidylcholine induces skeletal muscle myopathy that is aggravated by high‐fat diet feeding2021
- Author(s)
  Ferrara Patrick J.、Verkerke Anthony R. P.、Maschek J. Alan、Shahtout Justin L.、Siripoksup Piyarat、Eshima Hiroaki、Johnson Jordan M.、Petrocelli Jonathan J.、Mahmassani Ziad S.、Green Thomas D.、McClung Joseph M.、Cox James E.、Drummond Micah J.、Funai Katsuhiko
- Journal Title
  
  The FASEB Journal
  
  Volume: 35 Issue: 10
- DOI
  10.1096/fj.202101104r
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21K21271
[Journal Article] In vivo Ca2+ buffering capacity and microvascular oxygen pressures following muscle contractions in diabetic rat skeletal muscles: fiber-type specific effects.2015
- Author(s)
  Hiroaki Eshima, David C.Poole, Yutaka Kano.
- Journal Title
  
  Am J Physiol Regul Integr Comp Physiol.
  
  Volume: 309 Pages: 128-137
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15H06597
[Presentation] サルコペニアと廃用性筋萎縮における脂質ヒドロペルオキシドの役割2023
- Author(s)
  江島弘晃
- Organizer
  第13回分子骨格筋代謝研究会
- Invited
- Data Source
  KAKENHI-PROJECT-22K17745
[Presentation] 運動器に対する糖尿病の影響2023
- Author(s)
  江島弘晃
- Organizer
  日本糖尿病理学療法学会サテライトカンファレンス・シンポジウム3 運動器疾患と糖尿病
- Invited
- Data Source
  KAKENHI-PROJECT-22K17745
[Presentation] Novel insight into understanding diabetic myopathy; calcium dysregulation2022
- Author(s)
  Hiroaki Eshima
- Organizer
  3rd Edition of World Congress on “Endocrinology, Diabetes and Metabolism”
- Invited
- Data Source
  KAKENHI-PROJECT-22K17745
[Presentation] 糖尿病と骨格筋異常の病態2022
- Author(s)
  江島弘晃
- Organizer
  日本物理療法研究会第4回 SIGカンファレンス
- Invited
- Data Source
  KAKENHI-PROJECT-22K17745
[Presentation] 肥満・糖尿病を予防する健康科学の最新知見2022
- Author(s)
  江島弘晃
- Organizer
  第77回日本体力医学会大会
- Data Source
  KAKENHI-PROJECT-22K17745
[Presentation] 糖尿病性筋萎縮を理解するための新しい洞察～カルシウム代謝不全～2022
- Author(s)
  江島弘晃
- Organizer
  第77回日本体力医学会大会
- Data Source
  KAKENHI-PROJECT-22K17745
[Presentation] ミトコンドリア増大モデルによる筋細胞内Ca2+調節機構2016
- Author(s)
  江島弘晃、三浦進司、妹尾奈波、狩野豊
- Organizer
  第4回骨格筋生物学研究会
- Place of Presentation
  松本大学
- Year and Date
  2016-03-04
- Data Source
  KAKENHI-PROJECT-15H06597
[Presentation] 筋細胞内Ca2+調節におけるミトコンドリアの役割：PGC-1αマウスによる検証2015
- Author(s)
  江島弘晃、三浦進司、狩野豊
- Organizer
  第70回日本体力医学会
- Place of Presentation
  和歌山県民文化会館
- Year and Date
  2015-09-18
- Data Source
  KAKENHI-PROJECT-15H06597

1. KAKEHI Saori

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Eshima Hiroaki 江島 弘晃

江島 弘晃 エシマ ヒロアキ

Research Projects

Research Products

Co-Researchers

糖尿病性筋萎縮とサルコペニアに共通するリン脂質過酸化の役割解明と治療法の開発Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

2型糖尿病の筋力低下を防止する骨格筋ミトコンドリアの新たな制御機構の解明Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Development of therapies for sarcopenia focusing on novel cell death mechanismsPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

糖尿病による筋機能低下の分子メカニズムの解明Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Book] 7章-3 運動生理学から身体不活動の生理・分子生物学へ. エビデンスに基づく身体活動の科学（熊谷秋三, 田中茂穂, 藤井宣晴 編集）2016

Author(s)

Total Pages

Publisher

Data Source

[Journal Article] Sedentary behavior in mice induces metabolic inflexibility by suppressing skeletal muscle pyruvate metabolism.2024

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Lipid hydroperoxides promote sarcopenia through carbonyl stress2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] A chronic high‐fat diet does not exacerbate muscle atrophy in fast‐twitch skeletal muscle of aged mice2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Inhibition of skeletal muscle Lands cycle ameliorates weakness induced by physical inactivity.2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Impaired fatigue resistance, sarcoplasmic reticulum function, and mitochondrial activity in soleus muscle of db/db mice2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Metformin and leucine increase satellite cells and collagen remodeling during disuse and recovery in aged muscle2021

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Influence of Obesity and Type 2 Diabetes on Calcium Handling by Skeletal Muscle: Spotlight on the Sarcoplasmic Reticulum and Mitochondria2021

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Low lysophosphatidylcholine induces skeletal muscle myopathy that is aggravated by high‐fat diet feeding2021

Author(s)

Journal Title

DOI

Data Source

[Journal Article] In vivo Ca2+ buffering capacity and microvascular oxygen pressures following muscle contractions in diabetic rat skeletal muscles: fiber-type specific effects.2015

Author(s)

Journal Title

Data Source

[Presentation] サルコペニアと廃用性筋萎縮における 脂質ヒドロペルオキシドの役割2023

Author(s)

Eshima Hiroaki 江島弘晃

江島弘晃エシマヒロアキ

[Book] 7章-3 運動生理学から身体不活動の生理・分子生物学へ. エビデンスに基づく身体活動の科学（熊谷秋三, 田中茂穂, 藤井宣晴編集）2016

[Presentation] サルコペニアと廃用性筋萎縮における脂質ヒドロペルオキシドの役割2023