Aki Sho 安藝翔

Researcher Number	80767210
Other IDs
External Links
Affiliation (Current)	2025: 大阪大学, ヒューマン・メタバース疾患研究拠点, 特任講師(常勤) 2025: 東京大学, 先端科学技術研究センター, 特任助教
Affiliation (based on the past Project Information) *help	2024: 東京大学, 先端科学技術研究センター, 特任助教 2021 – 2022: 東京大学, 先端科学技術研究センター, 特任助教 2020: 金沢大学, 医学系, 協力研究員 2016 – 2019: 金沢大学, 医学系, 助教
Review Section/Research Field	Principal Investigator Basic Section 48020:Physiology-related / Basic Section 44010:Cell biology-related / General physiology
Keywords	Principal Investigator ホスホイノシタイド / ミトコンドリア / エンドサイトーシス / PI3K / 循環調節 / PI3キナーゼ / 超解像イメージング / オルガネラ / ミトファジー / ミトコンドリアダイナミクス … More / オルガネライメージング / PIPs / ミトコンドリア融合 / 周生期循環適応 / PI3K-C2β / PI3K-C2α / メンブレントラフィッキング / 平滑筋収縮 / 生理学 / 血管内皮細胞 / 細胞内小胞輸送 / 血管新生 Less

The mechanism of mitochondrial dynamics regulation via PIPsPrincipal Investigator
- Principal Investigator
  
  安藝翔
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 44010:Cell biology-related
- Research Institution
  The University of Tokyo
Regulation of cardiac and vascular function via membrane trafficking mediated by class II PI3KPrincipal Investigator
- Principal Investigator
  
  Aki Sho
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 48020:Physiology-related
- Research Institution
  The University of Tokyo
  Kanazawa University
New mechanisms of perinatal cardiovascular regulation by class II PI3KPrincipal Investigator
- Principal Investigator
  
  Aki Sho
- Project Period (FY)
  2018 – 2019
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 48020:Physiology-related
- Research Institution
  Kanazawa University
Class II PI3K regulate receptor endocytosis and endosomal signalingPrincipal Investigator
- Principal Investigator
  
  Aki Sho
- Project Period (FY)
  2016 – 2017
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  General physiology
- Research Institution
  Kanazawa University

All 2023 2022 2021 2020 2019 2018 2017 2016

All Journal Article Presentation

[Journal Article] Convergent genomic diversity and novel BCAA metabolism in intrahepatic cholangiocarcinoma2023
- Author(s)
  Kitagawa A, Osawa T,Noda M,Kobayashi Y, Aki S,Nakano Y,Saito T,Shimizu D,Komatsu H,Sugaya M,Takahashi J,...Mimori K.
- Journal Title
  
  Br J Cancer
  
  Volume: - Issue: 12 Pages: 22068-22068
- DOI
  10.1038/s41416-023-02256-4
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K08826, KAKENHI-PROJECT-20H04281, KAKENHI-PROJECT-20K07260, KAKENHI-PROJECT-20K21832, KAKENHI-PUBLICLY-22H04839, KAKENHI-PROJECT-23K18234, KAKENHI-PROJECT-22K07774, KAKENHI-PROJECT-22K09006, KAKENHI-PROJECT-21K08745, KAKENHI-PLANNED-23H04938, KAKENHI-PROJECT-22H04925, KAKENHI-PROJECT-23K24164
[Journal Article] Metabolic adaptations of cancer in extreme tumor microenvironments2023
- Author(s)
  Ryuichi Nakahara、Keisuke Maeda、Sho Aki、Tsuyoshi Osawa
- Journal Title
  
  Cancer Science
  
  Volume: 114 Issue: 4 Pages: 1200-1207
- DOI
  10.1111/cas.15722
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22H04925, KAKENHI-PROJECT-19H03496, KAKENHI-PROJECT-22KJ0927, KAKENHI-PROJECT-20K07260, KAKENHI-PROJECT-21K19399, KAKENHI-PROJECT-23K18234, KAKENHI-PROJECT-23KJ0581
[Journal Article] Cancer metabolism within tumor microenvironments2023
- Author(s)
  Aki Sho、Nakahara Ryuichi、Maeda Keisuke、Osawa Tsuyoshi
- Journal Title
  
  Biochimica et Biophysica Acta (BBA) - General Subjects
  
  Volume: 1867 Issue: 5 Pages: 130330-130330
- DOI
  10.1016/j.bbagen.2023.130330
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K07260, KAKENHI-PROJECT-23K18234, KAKENHI-PROJECT-23KJ0581, KAKENHI-PROJECT-22KJ0927, KAKENHI-PROJECT-22H04925
[Journal Article] Antibody mimetic drug conjugate manufactured by high-yield Escherichia coli expression and non-covalent binding system2022
- Author(s)
  Yamatsugu Kenzo、Katoh Hiroto、Yamashita Takefumi、Takahashi Kazuki、Aki Sho、Tatsumi Toshifumi、Kaneko Yudai、Kawamura Takeshi、Miura Mai、Ishii Masazumi、Ohkubo Kei、Osawa Tsuyoshi、Kodama Tatsuhiko、Ishikawa Shumpei、Kanai Motomu、Sugiyama Akira
- Journal Title
  
  Protein Expression and Purification
  
  Volume: 192 Pages: 106043-106043
- DOI
  10.1016/j.pep.2021.106043
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19H03510, KAKENHI-PROJECT-21H02779, KAKENHI-PROJECT-19H03496, KAKENHI-PROJECT-20H02779, KAKENHI-PROJECT-20K07260, KAKENHI-PROJECT-21K19399, KAKENHI-PUBLICLY-20H04819
[Journal Article] Pathological complete remission of relapsed tumor by photo‐activating antibody-mimetic drug conjugate treatment2022
- Author(s)
  Kaneko Yudai、Yamatsugu Kenzo、Yamashita Takefumi、Takahashi Kazuki、Tanaka Toshiya、Aki Sho、Tatsumi Toshifumi、Kawamura Takeshi、Miura Mai、Ishii Masazumi、Ohkubo Kei、Osawa Tsuyoshi、Kodama Tatsuhiko、Ishikawa Shumpei、Tsukagoshi Masanobu、Chansler Michael、Sugiyama Akira、Kanai Motomu、Katoh Hiroto
- Journal Title
  
  Cancer Science
  
  Volume: 113 Issue: 12 Pages: 4350-4362
- DOI
  10.1111/cas.15565
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-22H05024, KAKENHI-PROJECT-19H01032, KAKENHI-PROJECT-19H03496, KAKENHI-PROJECT-20H02779, KAKENHI-PROJECT-21H02779, KAKENHI-PROJECT-20K07260, KAKENHI-PROJECT-21K19399, KAKENHI-PUBLICLY-20H04819, KAKENHI-ORGANIZER-22H05017
[Journal Article] Class II phosphatidylinositol 3-kinase-C2α is essential for Notch signaling by regulating the endocytosis of γ-secretase in endothelial cells2021
- Author(s)
  Shimizu Shota、Yoshioka Kazuaki、Aki Sho、Takuwa Yoh
- Journal Title
  
  Scientific Reports
  
  Volume: 11 Issue: 1 Pages: 5199-5199
- DOI
  10.1038/s41598-021-84548-4
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K07273, KAKENHI-PROJECT-20K07260
[Journal Article] Class II phosphatidylinositol 3-kinase α and β isoforms are required for vascular smooth muscle Rho activation, contraction and blood pressure regulation in mice2020
- Author(s)
  Islam Shahidul、Yoshioka Kazuaki、Aki Sho、Ishimaru Kazuhiro、Yamada Hiroki、Takuwa Noriko、Takuwa Yoh
- Journal Title
  
  The Journal of Physiological Sciences
  
  Volume: 70 Issue: 1 Pages: 18-18
- DOI
  10.1186/s12576-020-00745-2
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K07864, KAKENHI-PROJECT-17K08532, KAKENHI-PROJECT-17K08542, KAKENHI-PROJECT-18K15010, KAKENHI-PROJECT-20K07260, KAKENHI-PROJECT-20K07273
[Journal Article] TGFβ receptor endocytosis and Smad signaling require synaptojanin1?, PI3K-C2α?, and INPP4B?mediated phosphoinositide conversions2020
- Author(s)
  Aki Sho、Yoshioka Kazuaki、Takuwa Noriko、Takuwa Yoh
- Journal Title
  
  Molecular Biology of the Cell
  
  Volume: 31(5) Issue: 5 Pages: 360-372
- DOI
  10.1091/mbc.e19-11-0662
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K08532, KAKENHI-PROJECT-17K08542, KAKENHI-PROJECT-18K15010, KAKENHI-PROJECT-20K07260, KAKENHI-PROJECT-20K07273
[Journal Article] The class II phosphoinositide 3-kinases PI3K-C2α and PI3K-C2β differentially regulate clathrin-dependent pinocytosis in human vascular endothelial cells.2019
- Author(s)
  Aung KT, Yoshioka K, Ishimaru K, Aki S, Takuwa N, and Takuwa Y.
- Journal Title
  
  Journal of Physiological Sciences
  
  Volume: 69 Issue: 2 Pages: 263-280
- DOI
  10.1007/s12576-018-0644-2
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K08532, KAKENHI-PROJECT-18K15010, KAKENHI-PROJECT-16K15409, KAKENHI-PROJECT-17K08542
[Journal Article] Class II PI3Ks α nad β are required for Rho-dependent uterine smooth muscle contraction and parturition in mice.2019
- Author(s)
  Sarker AK, Aki S, Yoshioka K, Kuno K, Okamoto Y, Ishimaru K, Takuwa N, and Takuwa Y.
- Journal Title
  
  Endocrinology
  
  Volume: 160 Issue: 1 Pages: 235-248
- DOI
  10.1210/en.2018-00756
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K08532, KAKENHI-PROJECT-17K08542, KAKENHI-PROJECT-18K15010, KAKENHI-PROJECT-16K15409
[Journal Article] Class II phosphoinositide 3-kinase isoforms PI3K-C2α and PI3K-C2β play essential roles in pinocytosis in vascular endothelial cells2018
- Author(s)
  Aung Thuzar Khin, Yoshioka Kazuaki, Aki Sho, Pham Quynh Hoa, Sarker Kabir Azadul, Islam Shahidul, Ishimaru Kazuhiro, Takuwa Noriko, Takuwa Yoh
- Journal Title
  
  The Journal of Physiological Sciences
  
  Volume: 68
- Data Source
  KAKENHI-PROJECT-16K18988
[Journal Article] MTMR4, a phosphoinositide specific 3’-phosphatase, regulates TFEB activity and the endocytic and autophagic pathways.2018
- Author(s)
  Pham HQ, Yoshioka K, Mohri H, Nakata H, Aki S, Ishimaru K, Takuwa N, and Takuwa Y.
- Journal Title
  
  Genes to Cells
  
  Volume: 23 Issue: 8 Pages: 670-687
- DOI
  10.1111/gtc.12609
- NAID
  120006621947
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K08532, KAKENHI-PROJECT-17K08542, KAKENHI-PROJECT-18K15010, KAKENHI-PROJECT-16K15409
[Journal Article] Sphingosine-1-phosphate receptor-2 facilitates pulmonary fibrosis through potentiating IL-13 pathway in macrophages.2018
- Author(s)
  Zhao J, Okamoto Y, Asano Y, Ishimaru K, Aki S, Yoshioka K, Takuwa N, Wada T, Inagaki Y, Takahashi C, Nishiuchi T, Takuwa Y.
- Journal Title
  
  PLoS One
  
  Volume: 13 Issue: 5 Pages: e0197604-e0197604
- DOI
  10.1371/journal.pone.0197604
- NAID
  120006605152
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K08542, KAKENHI-PROJECT-18K15010, KAKENHI-PLANNED-17H06394, KAKENHI-PROJECT-17H04166, KAKENHI-PROJECT-16K15409
[Journal Article] Myotubularin-related protein 4 (MTMR4), a phosphoinositide 3'-phosphatase, regulates endolysosome integrity and autophagy flux in human lung alveolar epithelial A549 cells2018
- Author(s)
  Pham Quynh Hoa, Yoshioka Kazuaki, Azadul Sarker Kabir, Aung Thuzar Khin, Islam Shahidul, Aki Sho, Ishimaru Kazuhiro, Takuwa Noriko1, Takuwa Yoh
- Journal Title
  
  The Journal of Physiological Sciences
  
  Volume: 68
- Data Source
  KAKENHI-PROJECT-16K18988
[Journal Article] Indispensable role of α and β isoforms of class II phosphoinositide 3-kinases (PI3K) in the uterine smooth muscle contraction during labor2018
- Author(s)
  Sarker Kabir Azadul, Sho Aki, Yoshioka Kazuaki, Kuno Koji, Okamoto Yasuo, Aung Thuzar Khin, Pham Quynh Hoa, Islam Shahidul, Takuwa Noriko, Takuwa Yoh
- Journal Title
  
  The Journal of Physiological Sciences
  
  Volume: 68
- Data Source
  KAKENHI-PROJECT-16K18988
[Presentation] PPIを介したミトコンドリアダイナミクス制御の新機構2022
- Author(s)
  安藝翔、大澤毅
- Organizer
  第4回がんと代謝若手研究会
- Data Source
  KAKENHI-PROJECT-20K07260
[Presentation] PPIを介したミトコンドリアダイナミクス制御の新機構2022
- Author(s)
  安藝翔、大澤毅
- Organizer
  第8回がんと代謝研究会
- Data Source
  KAKENHI-PROJECT-20K07260
[Presentation] PPIを介したミトコンドリアダイナミクス制御の新機構2022
- Author(s)
  安藝翔、大澤毅
- Organizer
  第95回日本生化学会大会
- Data Source
  KAKENHI-PROJECT-20K07260
[Presentation] PPIを介したミトコンドリアダイナミクス制御の新機構2022
- Author(s)
  Sho Aki
- Organizer
  第99回日本生理学会年会 (第12回入澤宏・彩記念若手研究奨励賞日本生理学会奨励賞)
- Invited
- Data Source
  KAKENHI-PROJECT-20K07260
[Presentation] The mechanism of mitochondrial dynamics regulation via PPI2022
- Author(s)
  Sho Aki、Tsuyoshi Osawa
- Organizer
  12th AACR-JCA Joint Conference
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K07260
[Presentation] The mechanism of mitochondrial dynamics regulation via PPI2022
- Author(s)
  Sho Aki、Tsuyoshi Osawa
- Organizer
  第45回日本分子生物学会
- Data Source
  KAKENHI-PROJECT-20K07260
[Presentation] PPIを介したミトコンドリアダイナミクス制御の新機構2022
- Author(s)
  安藝翔、大澤毅
- Organizer
  第81回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-20K07260
[Presentation] 連続するホスホイノシタイド代謝がTGFβ受容体エンドサイトーシス及びSmad2/3 活性化に必須である2021
- Author(s)
  安藝　翔
- Organizer
  第98回日本生理学会大会
- Data Source
  KAKENHI-PROJECT-20K07260
[Presentation] Sequential phosphoinositide conversion is required for TGFb-induced receptor endocytosis for angiogenesis.2021
- Author(s)
  Sho Aki
- Organizer
  第80回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-20K07260
[Presentation] The mechanism of mitochondrial dynamics regulation via PPI2021
- Author(s)
  Sho Aki
- Organizer
  第44回日本分子生物学会年会. (ワークショップ：生命科学の根幹に迫るミトコンドリアダイナミクスの世界)
- Invited
- Data Source
  KAKENHI-PROJECT-20K07260
[Presentation] Differential roles of class II PI3-kinase-C2α and -C2β in clathrinmediated fluid phase endocytosis in vascular endothelial cells2020
- Author(s)
  Kazuaki Yoshioka, Sho Aki, Noriko Takuwa, Yoh Takuwa
- Organizer
  第９７回　日本生理学会大会（大分・別府）
- Data Source
  KAKENHI-PROJECT-18K15010
[Presentation] 血管新生因子TGFβ/Smadシグナリングを制御するホスホイノシタイドカスケード2020
- Author(s)
  安藝　翔
- Organizer
  第97回日本生理学会大会. (シンポジウム：Angiology evolving into new research fields)
- Invited
- Data Source
  KAKENHI-PROJECT-20K07260
[Presentation] Sequential phosphoinositide conversion is required for TGFβ-induced receptor endocytosis and endosomal receptor signaling in endothelial cells2020
- Author(s)
  Sho Aki, Kazuaki Yoshioka, Noriko Takuwa, Yoh Takuwa
- Organizer
  第９７回　日本生理学会大会（大分・別府）
- Invited
- Data Source
  KAKENHI-PROJECT-18K15010
[Presentation] TGFβ/Smadシグナリングを制御するホスホイノシタイドカスケード2020
- Author(s)
  安藝　翔
- Organizer
  金沢大学「機能脂質シンポジウム」〝生命機能と疾患を制御する機能脂質〟
- Invited
- Data Source
  KAKENHI-PROJECT-20K07260
[Presentation] Differential roles of class II PI3K in endocytosis and endosomal signaling2019
- Author(s)
  Kazuaki Yoshioka, Khin Thuzar Aung, Md Azadul Kabir Sarker, Sho Aki, Kuntal Biswas, Noriko Takuwa, Yoh Takuwa
- Organizer
  60th International Conference on the Bioscience of Lipids, Hitotsubashi Hall (Tokyo)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K15010
[Presentation] 脂質リン酸化酵素II型PI3キナーゼによる循環機能制御の新機構2019
- Author(s)
  安藝翔
- Organizer
  第5回血管生物若手研究会
- Data Source
  KAKENHI-PROJECT-18K15010
[Presentation] 細胞膜イノシトールリン脂質脱リン酸化酵素・MTMR4による細胞内クリアランスの制御2019
- Author(s)
  吉岡和晃、Quynh Hoa Pham、安藝　翔、多久和典子、多久和　陽
- Organizer
  第92回日本生化学会大会、横浜パシフィコ（横浜）
- Data Source
  KAKENHI-PROJECT-18K15010
[Presentation] Sequential phosphoinositide conversion is required for transforming growth factor β-induced receptor endocytosis and Smad2/3 activation in endothelial cells2019
- Author(s)
  Sho Aki, Kazuaki Yoshioka, Noriko Takuwa, Yoh Takuwa
- Organizer
  60th International Conference on the Bioscience of Lipids, Hitotsubashi Hall (Tokyo)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K15010
[Presentation] Sequential phosphoinositide conversion is required for transforming growth factor -induced receptor endocytosis and Smad2/3 activation in endothelial cells2019
- Author(s)
  Sho Aki
- Organizer
  FAOPS2019
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K15010
[Presentation] 連続するホスホイノシタイド代謝がTGFβ受容体エンドサイトーシス及びSmad2/3 活性化に必須である2019
- Author(s)
  安藝　翔、吉岡和晃、多久和典子、多久和　陽
- Organizer
  第61回日本脂質生化学会、北海道大学（札幌）
- Data Source
  KAKENHI-PROJECT-18K15010
[Presentation] 連続するホスホイノシタイド代謝がTGFβ受容体エンドサイトーシス及びSmad2/3活性化に必須である2019
- Author(s)
  安藝　翔、吉岡和晃、Islam Shahidul、多久和典子、多久和　陽
- Organizer
  第92回日本生化学会大会、横浜パシフィコ（横浜）
- Data Source
  KAKENHI-PROJECT-18K15010
[Presentation] イノシトールリン脂質3’脱リン酸化酵素MTMR4 による細胞内クリアランス制御メカニズム2019
- Author(s)
  吉岡和晃、Quynh Hoa Pham、安藝　翔、多久和典子、多久和　陽
- Organizer
  第61回日本脂質生化学会、北海道大学（札幌）
- Data Source
  KAKENHI-PROJECT-18K15010
[Presentation] 脂質リン酸化酵素クラスII型PI3キナーゼによる循環機能制御の新機構2019
- Author(s)
  安藝　翔
- Organizer
  先端モデル動物支援プラットフォーム若手支援技術講習会(蓼科)
- Data Source
  KAKENHI-PROJECT-18K15010
[Presentation] 脂質リン酸化酵素II型PI3キナーゼによる循環機能制御の新機構2018
- Author(s)
  Sho Aki
- Organizer
  第4回血管生物若手研究会
- Data Source
  KAKENHI-PROJECT-16K18988
[Presentation] 脂質リン酸化酵素II型PI3キナーゼによる血管機能制御の新機構2017
- Author(s)
  Sho Aki
- Organizer
  第3回血管生物若手研究会
- Data Source
  KAKENHI-PROJECT-16K18988
[Presentation] クラスII PI3-キナーゼ PI3K-C2αはエンドソーム上でのTGFβ/Smad2/3シグナリングに必須である2016
- Author(s)
  安藝　翔
- Organizer
  第39回日本分子生物学会年会
- Place of Presentation
  パシフィコ横浜
- Year and Date
  2016-11-30
- Data Source
  KAKENHI-PROJECT-16K18988
[Presentation] Phosphatidylinositol 3-kinase class II α isoform PI3K-C2α is required for transforming growth factor β-induced receptor endocytosis and endosomal signaling in endothelial cells2016
- Author(s)
  Sho Aki
- Organizer
  第2回春期特別日本血管生物医学会シンポジウム
- Place of Presentation
  大阪大学微生物病研究所　谷口記念講堂
- Year and Date
  2016-06-03
- Invited
- Data Source
  KAKENHI-PROJECT-16K18988

1. Azadul Sarker Kabir

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
2. Khin Aung Thuzar

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
3. 吉岡和晃

# of Collaborated Projects: 0 results

# of Collaborated Products: 5 results
4. 杉山暁

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
5. 多久和典子

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
6. 高橋純一

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
7. 三森功士

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
8. 石丸和宏

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Aki Sho 安藝 翔

Research Projects

Research Products

Co-Researchers

The mechanism of mitochondrial dynamics regulation via PIPsPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Regulation of cardiac and vascular function via membrane trafficking mediated by class II PI3KPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

New mechanisms of perinatal cardiovascular regulation by class II PI3KPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Class II PI3K regulate receptor endocytosis and endosomal signalingPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Convergent genomic diversity and novel BCAA metabolism in intrahepatic cholangiocarcinoma2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Metabolic adaptations of cancer in extreme tumor microenvironments2023

Author(s)

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DOI

Data Source

[Journal Article] Cancer metabolism within tumor microenvironments2023

Author(s)

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DOI

Data Source

[Journal Article] Antibody mimetic drug conjugate manufactured by high-yield Escherichia coli expression and non-covalent binding system2022

Author(s)

Journal Title

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[Journal Article] Pathological complete remission of relapsed tumor by photo‐activating antibody-mimetic drug conjugate treatment2022

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[Journal Article] Class II phosphatidylinositol 3-kinase-C2α is essential for Notch signaling by regulating the endocytosis of γ-secretase in endothelial cells2021

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[Journal Article] Class II phosphatidylinositol 3-kinase α and β isoforms are required for vascular smooth muscle Rho activation, contraction and blood pressure regulation in mice2020

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[Journal Article] TGFβ receptor endocytosis and Smad signaling require synaptojanin1?, PI3K-C2α?, and INPP4B?mediated phosphoinositide conversions2020

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[Journal Article] The class II phosphoinositide 3-kinases PI3K-C2α and PI3K-C2β differentially regulate clathrin-dependent pinocytosis in human vascular endothelial cells.2019

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[Journal Article] Class II PI3Ks α nad β are required for Rho-dependent uterine smooth muscle contraction and parturition in mice.2019

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[Journal Article] Class II phosphoinositide 3-kinase isoforms PI3K-C2α and PI3K-C2β play essential roles in pinocytosis in vascular endothelial cells2018

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Aki Sho 安藝翔