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Nishiyama Akihiro  西山 明宏

ORCIDConnect your ORCID iD *help
Researcher Number 80770172
Other IDs
Affiliation (Current) 2025: 金沢大学, がん進展制御研究所, 助教
Affiliation (based on the past Project Information) *help 2025: 金沢大学, がん進展制御研究所, 助教
2018 – 2022: 金沢大学, がん進展制御研究所, 助教
Review Section/Research Field
Principal Investigator
Basic Section 50020:Tumor diagnostics and therapeutics-related / Basic Section 50010:Tumor biology-related
Keywords
Principal Investigator
臓器横断的 / 髄膜癌腫症 / 肺がん / RET融合遺伝子 / 分子標的耐性 / BRAF遺伝子変異 / 甲状腺がん / 分子標的薬耐性 / サイトカイン活性 / BRAF V600E … More / 甲状腺未分化がん / 中枢神経転移 / 中等度耐性 / 高度耐性 / TRK阻害薬 / NTRK融合遺伝子 / 耐性機序 / エヌトレクチニブ / がん腫横断的 / NTRK1融合遺伝子 Less
  • Research Projects

    (3 results)
  • Research Products

    (3 results)
  •  肺がんマウス中枢神経病変モデルによる薬剤耐性機序と髄膜がん腫症メカニズムの解明Principal Investigator

    • Principal Investigator
      西山 明宏
    • Project Period (FY)
      2025 – 2029
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 50010:Tumor biology-related
    • Research Institution
      Kanazawa University
  •  Basic research for overcoming of target therapy resistance in anaplastic thyroid carcinoma with BRAF V600EPrincipal Investigator

    • Principal Investigator
      Nishiyama Akihiro
    • Project Period (FY)
      2020 – 2022
    • Research Category
      Grant-in-Aid for Early-Career Scientists
    • Review Section
      Basic Section 50020:Tumor diagnostics and therapeutics-related
    • Research Institution
      Kanazawa University
  •  Basic research for the resistant mechanism and overcoming method in NTRK1 fusion positive cancerPrincipal Investigator

    • Principal Investigator
      Nishiyama Akihiro
    • Project Period (FY)
      2018 – 2019
    • Research Category
      Grant-in-Aid for Early-Career Scientists
    • Review Section
      Basic Section 50020:Tumor diagnostics and therapeutics-related
    • Research Institution
      Kanazawa University

All 2020 2018

All Journal Article Presentation

  • [Journal Article] Foretinib Overcomes Entrectinib Resistance Associated with NTRK1 G667C Mutation in NTRK1 Fusion-Positive Tumor Cells in a Brain Metastasis Model2018

    • Author(s)
      Akihiro Nishiyama
    • Journal Title

      Clinical Cancer Research

      Volume: 24 Issue: 10 Pages: 23572369-23572369

    • DOI

      10.1158/1078-0432.ccr-17-1623

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18K15308, KAKENHI-PROJECT-16H05308
  • [Presentation] NTRK融合遺伝子陽性がんの中枢神経転移における分子標的薬耐性の機構解明と克服薬開発2020

    • Author(s)
      西山明宏
    • Organizer
      第1回日本癌学会若手の会
    • Data Source
      KAKENHI-PROJECT-18K15308
  • [Presentation] NTRK1融合遺伝子陽性癌におけるエントレクチニブ耐性機構の解明と耐性克服薬開発2018

    • Author(s)
      西山 明宏
    • Organizer
      第1回金沢大学がん進展制御研究所・国立がんセンター若手研究発表会
    • Data Source
      KAKENHI-PROJECT-18K15308

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