MATSUNAGA Yuki 松永裕希

… Alternative Names

Matsunaga Yuki 松永裕希

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Researcher Number	80772136
Other IDs	https://orcid.org/0000-0001-5562-9883
Affiliation (Current)	2025: 長崎大学, 病院(医学系), 助教
Affiliation (based on the past Project Information) *help	2021 – 2023: 長崎大学, 医歯薬学総合研究科(医学系), 客員研究員 2019 – 2023: 長崎大学, 病院(医学系), 医員
Review Section/Research Field	Principal Investigator Basic Section 56010:Neurosurgery-related Except Principal Investigator Basic Section 56010:Neurosurgery-related / Medium-sized Section 90:Biomedical engineering and related fields
Keywords	Principal Investigator In vitro model / in vitroモデル / 血液脳関門 / 造影剤 / MAP kinase / 造影剤脳症 / Fasudil / アストロサイト / ペリサイト / 脳卒中 / Rho kinase阻害薬 … More Except Principal Investigator … More 血液脳関門 / drug repositioning / がん / ぺリサイト / 脳虚血 / 血液脳関門モデル / 中枢神経薬剤開発 / ドラッグリポジショニング / 脳卒中 / 保護薬 / 中枢神経 / 3次元モデル / pericyte / contrast encepalopathy / fasudil hydorochloride / blood brain barrier / 初代培養細胞 / in vitro model / in vitroモデル / 中枢神経疾患治療薬 / Rho kinase阻害薬 Less

血液脳関門モデルを用いた造影剤脳症の作用機序解明と治療法探求Principal Investigator
- Principal Investigator
  
  松永裕希
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56010:Neurosurgery-related
- Research Institution
  Nagasaki University
灌流型３次元血液脳関門モデルを用いた中枢神経保護薬の探求
- Principal Investigator
  
  出雲剛
- Project Period (FY)
  2021 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56010:Neurosurgery-related
- Research Institution
  Gifu University
  Nagasaki University
Drug development of central nervous system disease using drug re-positioning
- Principal Investigator
  
  Morofuji Yoichi
- Project Period (FY)
  2020 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56010:Neurosurgery-related
- Research Institution
  Nagasaki University
Drug development of central nervous system diseases using dynamic three-dimensional in vitro blood-brain barrier model
- Principal Investigator
  
  諸藤陽一
- Project Period (FY)
  2020 – 2025
- Research Category
  
  Fund for the Promotion of Joint International Research (Fostering Joint International Research (B))
- Review Section
  
  Medium-sized Section 90:Biomedical engineering and related fields
- Research Institution
  Nagasaki University
Breakthrough of the effect and mechanism of Rho kinase inhibitor fasudil on blood-brain barrierPrincipal Investigator
- Principal Investigator
  
  Matsunaga Yuki
- Project Period (FY)
  2019 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56010:Neurosurgery-related
- Research Institution
  Nagasaki University

All 2025 2024 2023 2022 2021 2020 2019

All Journal Article Presentation

[Journal Article] Non-Sinus Type Dural Arteriovenous Fistula: Others2025
- Author(s)
  Morofuji Yoichi、Morikawa Minoru、Horie Nobutaka、Matsunaga Yuki、Izumo Tsuyoshi、Matsuo Takayuki
- Journal Title
  
  Journal of Neuroendovascular Therapy
  
  Volume: 19 Issue: 1 Pages: n/a
- DOI
  10.5797/jnet.ra.2023-0023
- ISSN
  1882-4072, 2186-2494
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20KK0254, KAKENHI-PROJECT-22K09287
[Journal Article] Evolving approaches in the management of patients with subarachnoid hemorrhage from 2002 to 2022: The impact of clazosentan and treatment modalities on outcomes2024
- Author(s)
  Maeda Hajime、Izumo Tsuyoshi、Okamura Kazuaki、Yamaguchi Susumu、Morofuji Yoichi、Matsuo Takayuki
- Journal Title
  
  Brain Hemorrhages
  
  Volume: 5 Issue: 2 Pages: 55-61
- DOI
  10.1016/j.hest.2023.11.006
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20KK0254, KAKENHI-PROJECT-20K09351
[Journal Article] Effects of fasudil on blood?brain barrier integrity2022
- Author(s)
  Sato Kei、Nakagawa Shinsuke、Morofuji Yoichi、Matsunaga Yuki、Fujimoto Takashi、Watanabe Daisuke、Izumo Tsuyoshi、Niwa Masami、Walter Fruzsina R.、Vigh Judit P.、Santa-Maria Ana Raquel、Deli Maria A.、Matsuo Takayuki
- Journal Title
  
  Fluids and Barriers of the CNS
  
  Volume: 19 Issue: 1 Pages: 43-43
- DOI
  10.1186/s12987-022-00336-w
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K09351, KAKENHI-PROJECT-21K09180, KAKENHI-PROJECT-22K09287, KAKENHI-PROJECT-20KK0254, KAKENHI-PROJECT-18K08973, KAKENHI-PROJECT-19K09531
[Journal Article] Impact of Pre-operative Embolization With Onyx for Brain Arteriovenous Malformation Surgery2022
- Author(s)
  Izumo Tsuyoshi、Okamura Kazuaki、Takahira Ryotaro、Matsunaga Yuki、Sadakata Eisaku、Maeda Hajime、Yamaguchi Susumu、Baba Shiro、Morofuji Yoichi、Hiu Takeshi、Horie Nobutaka、Anda Takeo、Kitagawa Naoki、Tokunaga Yoshiharu、Hayashi Kentaro、Matsumoto Yasushi、Nagata Izumi、Matsuo Takayuki
- Journal Title
  
  Frontiers in Neurology
  
  Volume: 13 Pages: 1-7
- DOI
  10.3389/fneur.2022.875260
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K09351, KAKENHI-PROJECT-22K09287, KAKENHI-PROJECT-20KK0254
[Journal Article] MAP Kinase Pathways in Brain Endothelial Cells and Crosstalk with Pericytes and Astrocytes Mediate Contrast-Induced Blood-Brain Barrier Disruption2021
- Author(s)
  Matsunaga Yuki、Nakagawa Shinsuke、Morofuji Yoichi、Dohgu Shinya、Watanabe Daisuke、Horie Nobutaka、Izumo Tsuyoshi、Niwa Masami、Walter Fruzsina R.、Santa-Maria Ana Raquel、Deli Maria A.、Matsuo Takayuki
- Journal Title
  
  Pharmaceutics
  
  Volume: 13 Issue: 8 Pages: 1272-1272
- DOI
  10.3390/pharmaceutics13081272
- NAID
  120007172250
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K10840, KAKENHI-PROJECT-18K08973, KAKENHI-PROJECT-19K09531, KAKENHI-PROJECT-20K09351, KAKENHI-PROJECT-21K09180, KAKENHI-PROJECT-20KK0254
[Journal Article] Delayed Vasospasm Associated with Mechanical Thrombectomy for Acute Ischemic Stroke2020
- Author(s)
  Matsunaga Yuki、Morofuji Yoichi、Horie Nobutaka
- Journal Title
  
  World Neurosurgery
  
  Volume: 138 Pages: 197-199
- DOI
  10.1016/j.wneu.2020.03.027
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15KK0349, KAKENHI-PROJECT-17K10840, KAKENHI-PROJECT-19K09531
[Journal Article] Carotid-Carotid Bypass for a Carotid Artery Aneurysm2020
- Author(s)
  Morofuji Yoichi、Matsunaga Yuki、Izumo Tsuyoshi
- Journal Title
  
  World Neurosurgery
  
  Volume: 138 Pages: 7-8
- DOI
  10.1016/j.wneu.2020.02.113
- NAID
  120006988257
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15KK0349, KAKENHI-PROJECT-17K10840, KAKENHI-PROJECT-20K09351, KAKENHI-PROJECT-20KK0254
[Journal Article] 症例副中大脳動脈に関連した塞栓性脳梗塞に対して急性期血行再建術を施行した1例2019
- Author(s)
  松永裕希、林健太郎、岡村宗晃、林之茂、白川靖、岩永充人、松尾孝之
- Journal Title
  
  Neurological Surgery 脳神経外科
  
  Volume: 47 Issue: 11 Pages: 1165-1171
- DOI
  10.11477/mf.1436204094
- ISSN
  0301-2603, 1882-1251
- Year and Date
  2019-11-10
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K09531
[Presentation] 造影剤の種類と血液脳関門への影響ダイマー型造影剤はモノマー型造影剤に比して血液脳関門障害性が低い2023
- Author(s)
  松永裕希、諸藤陽一、白川靖、陶山一彦
- Organizer
  第39回NPO法人日本脳神経血管内治療学会学術集会
- Data Source
  KAKENHI-PROJECT-22K09287
[Presentation] 造影剤の種類と血液脳関門への影響ダイマー型造影剤はモノマー型造影剤に比して血液脳関門障害性が低い2023
- Author(s)
  松永裕希、諸藤陽一、白川靖、陶山一彦
- Organizer
  日本脳神経外科学会第82回学術総会
- Data Source
  KAKENHI-PROJECT-22K09287
[Presentation] MAP kinase pathways in brain endothelial cells mediate contrast-induced blood-brain barrier disruption2022
- Author(s)
  Yuki Matsunaga, Shinsuke Nakagawa, Yoichi Morofuji, Shinya Dohgu, Daisuke Watanabe, Nobutaka Horie, Tsuyoshi Izumo, Masami Niwa, Fruzsina R. Walter, Ana Raquel Santa-Maria, Maria A. Deli, Takayuki Matsuo
- Organizer
  4rd Mini-symposium on the blood-brain barrier from basic to clinical research
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K09531
[Presentation] MAP kinase pathways in brain endothelial cells mediates contrast induced blood brain barrier disruption2022
- Author(s)
  Yuki Matsunaga, Yoichi Morofuji, Tsuyoshi Izumo, Takayuki Matsuo, Kazuhiko Suyama
- Organizer
  The 14th World Stroke Congress
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K09287
[Presentation] 造影剤脳症の発症機序解析　ペリサイト、アストロサイトのクロストークが造影剤誘発性血液脳関門障害に関与する2022
- Author(s)
  松永裕希, 諸藤陽一, 白川靖, 陶山一彦
- Organizer
  第38回NPO法人日本脳神経血管内治療学会学術集会
- Data Source
  KAKENHI-PROJECT-22K09287
[Presentation] MAP kinase pathways in brain endothelial cells mediate contrast-induced blood brain barrier disruption.2022
- Author(s)
  Yuki Matsunaga, Shinsuke Nakagawa, Yoichi Morofuji, Shinya Dohgu, Daisuke Watanabe, Nobutaka Horie, Tsuyoshi Izumo, Masami Niwa, Fruzsina R. Walter, Ana Raquel Santa-Maria, Maria A. Deli, Takayuki Matsuo
- Organizer
  4th Mini-symposium on the blood-brain barrier from basic to clinical research
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K09287
[Presentation] ペリサイト、アストロサイトのクロストークが造影剤誘発性血液脳関門障害に関与する2022
- Author(s)
  松永裕希、諸藤陽一、白川靖、陶山一彦
- Organizer
  日本脳神経外科学会第81回学術総会
- Data Source
  KAKENHI-PROJECT-22K09287
[Presentation] 脳内皮細胞内MAPキナーゼ経路とPericyte, Astrocyteのクロストークが造影剤誘発性血液脳関門障害に関与する2022
- Author(s)
  松永裕希,諸藤陽一.中川慎介,陶山一彦,松尾孝之
- Organizer
  第51回日本神経放射線学会
- Data Source
  KAKENHI-PROJECT-22K09287
[Presentation] Contrast-induced blood-brain barrier disruption2021
- Author(s)
  Yuki Matsunaga, Yoichi Morofuji, Shinsuke Nakagawa, Nobutaka Horie, Tsuyoshi Izumo, Takeo Anda, Masami Niwa, Takayuki Matsuo
- Organizer
  3rd Mini-symposium on the blood-brain barrier from basic to clinical research
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K09531
[Presentation] MAP kinase経路とペリサイト、アストロサイトのクロストークが造影剤誘発性血液脳関門障害に関与する2021
- Author(s)
  松永裕希, 中川慎介, 諸藤陽一, 堀江信貴, 出雲剛, 陶山一彦, 松尾孝之
- Organizer
  第37回NPO法人日本脳神経血管内治療学会学術集会
- Data Source
  KAKENHI-PROJECT-19K09531
[Presentation] 頸動脈狭窄を背景に持つTandem閉塞に対する急性期血行再建術の戦略と治療成績:Retrograde reperfusionを主体とした治療2021
- Author(s)
  松永裕希, 定方英作, 出雲剛, 堀江信貴, 案田岳夫, 白川靖, 陶山一彦, 松尾孝之
- Organizer
  日本脳神経外科学会第80回学術総会
- Data Source
  KAKENHI-PROJECT-19K09531
[Presentation] 血液脳関門をターゲットとした脳梗塞治療薬の開発2021
- Author(s)
  諸藤陽一、中川慎介、佐藤慧、松永裕希、藤本隆史、堀江信貴、出雲剛、松尾孝之
- Organizer
  日本脳神経外科学会　第80回学術総会
- Data Source
  KAKENHI-PROJECT-20K09351
[Presentation] Intraarterial therapy of Rho-kinase inhibitor for acute ischemic stroke2021
- Author(s)
  Morofuji Y, Nakagawa S, Sato K, Matsunaga Y, Fujimoto T, Izumo T, Niwa M, Matsuo T
- Organizer
  The 13th World Stroke Congress
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20KK0254
[Presentation] Intraarterial therapy of Rho-kinase inhibitor for acute ischemic stroke2021
- Author(s)
  Morofuji Y, Nakagawa S, Sato K, Matsunaga Y, Fujimoto T, Izumo T, Niwa M, Matsuo T
- Organizer
  The 13th World Stroke Congress
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K09351
[Presentation] 血液脳関門をターゲットとした脳梗塞治療薬の開発2021
- Author(s)
  諸藤陽一、中川慎介、佐藤慧、松永裕希、藤本隆史、堀江信貴、出雲剛、松尾孝之
- Organizer
  日本脳神経外科学会　第80回学術総会
- Data Source
  KAKENHI-PROJECT-20KK0254
[Presentation] 急性期脳梗塞治療としてのファスジル動注療法の可能性2020
- Author(s)
  諸藤陽一、中川慎介、藤本隆史、佐藤慧、松永裕希
- Organizer
  第36回日本脳神経血管内治療学会
- Data Source
  KAKENHI-PROJECT-20K09351
[Presentation] 急性期脳梗塞治療としてのファスジル動注療法の可能性2020
- Author(s)
  諸藤陽一、中川慎介、藤本隆史、佐藤慧、松永裕希
- Organizer
  第36回日本脳神経血管内治療学会
- Data Source
  KAKENHI-PROJECT-20KK0254
[Presentation] 急性期脳梗塞治療としてのファスジル動注療法の可能性2020
- Author(s)
  諸藤陽一、中川慎介、藤本隆史、佐藤慧、松永裕希
- Organizer
  Stroke2021
- Data Source
  KAKENHI-PROJECT-20KK0254
[Presentation] A cell culture based model of the blood-brain barrier to study brain metastatic potential of cancer cells2020
- Author(s)
  Yuki Matsunaga
- Organizer
  2nd Mini-symposium on the blood-brain barrier from basic to clinical research
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K09531
[Presentation] 頸動脈狭窄を背景に持つTandem閉塞に対する急性期血行再建術の戦略と治療成績: Retrograde reperfusionを主体とした治療2020
- Author(s)
  松永裕希、定方英作、出雲剛、堀江信貴、案田岳夫、松尾孝之
- Organizer
  第36回日本脳神経血管内治療学会
- Data Source
  KAKENHI-PROJECT-19K09531
[Presentation] 急性期脳梗塞治療としてのファスジル動注療法の可能性2020
- Author(s)
  諸藤陽一、中川慎介、藤本隆史、佐藤慧、松永裕希
- Organizer
  Stroke2021
- Data Source
  KAKENHI-PROJECT-20K09351
[Presentation] 造影剤が与える血液脳関門に対する影響2020
- Author(s)
  松永裕希、佐藤慧、諸藤陽一、中川慎介、出雲剛、堀江信貴、案田岳夫、松尾孝之
- Organizer
  第79回日本脳神経外科学会総会
- Data Source
  KAKENHI-PROJECT-19K09531
[Presentation] A cell culture based model of the blood-brain barrier to study brain metastatic potential of cancer cells2019
- Author(s)
  Yuki Matsunaga
- Organizer
  3rd joint symposium between Nagasaki University and Wurzburg university
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K09531
[Presentation] Parent artery Occlusion for traumatic vertebral artery injury2019
- Author(s)
  Yuki Matsunaga
- Organizer
  The 15th congress of the World Federation of Interventional Therapeutic Neuroradiology
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K09531

1. Morofuji Yoichi (40437869)

# of Collaborated Projects: 5 results

# of Collaborated Products: 25 results
2. 中川慎介 (10404211)

# of Collaborated Projects: 4 results

# of Collaborated Products: 15 results
3. 佐藤慧 (40849486)

# of Collaborated Projects: 2 results

# of Collaborated Products: 9 results
4. 藤本隆史 (00712085)

# of Collaborated Projects: 1 results

# of Collaborated Products: 4 results
5. 出雲剛 (40343347)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results

MATSUNAGA Yuki 松永 裕希

Matsunaga Yuki 松永 裕希

Research Projects

Research Products

Co-Researchers

血液脳関門モデルを用いた造影剤脳症の作用機序解明と治療法探求Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

灌流型３次元血液脳関門モデルを用いた中枢神経保護薬の探求

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Drug development of central nervous system disease using drug re-positioning

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Drug development of central nervous system diseases using dynamic three-dimensional in vitro blood-brain barrier model

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Breakthrough of the effect and mechanism of Rho kinase inhibitor fasudil on blood-brain barrierPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

[Journal Article] Non-Sinus Type Dural Arteriovenous Fistula: Others2025

Author(s)

Journal Title

DOI

ISSN

Language

Data Source

[Journal Article] Evolving approaches in the management of patients with subarachnoid hemorrhage from 2002 to 2022: The impact of clazosentan and treatment modalities on outcomes2024

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Effects of fasudil on blood?brain barrier integrity2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Impact of Pre-operative Embolization With Onyx for Brain Arteriovenous Malformation Surgery2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] MAP Kinase Pathways in Brain Endothelial Cells and Crosstalk with Pericytes and Astrocytes Mediate Contrast-Induced Blood-Brain Barrier Disruption2021

Author(s)

Journal Title

DOI

NAID

Data Source

[Journal Article] Delayed Vasospasm Associated with Mechanical Thrombectomy for Acute Ischemic Stroke2020

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Carotid-Carotid Bypass for a Carotid Artery Aneurysm2020

Author(s)

Journal Title

DOI

NAID

Data Source

[Journal Article] 症例 副中大脳動脈に関連した塞栓性脳梗塞に対して急性期血行再建術を施行した1例2019

Author(s)

Journal Title

DOI

ISSN

Year and Date

MATSUNAGA Yuki 松永裕希

Matsunaga Yuki 松永裕希

[Journal Article] 症例副中大脳動脈に関連した塞栓性脳梗塞に対して急性期血行再建術を施行した1例2019

[Presentation] 造影剤の種類と血液脳関門への影響ダイマー型造影剤はモノマー型造影剤に比して血液脳関門障害性が低い2023

[Presentation] 造影剤の種類と血液脳関門への影響ダイマー型造影剤はモノマー型造影剤に比して血液脳関門障害性が低い2023

[Presentation] 造影剤脳症の発症機序解析　ペリサイト、アストロサイトのクロストークが造影剤誘発性血液脳関門障害に関与する2022