ARAI Yasuha 荒井泰葉

Researcher Number	80793182
Affiliation (based on the past Project Information) *help	2018 – 2023: 京都府立医科大学, 医学(系)研究科(研究院), 研究員 2017: 京都府立医科大学, 医学研究科, 博士研究員
Review Section/Research Field	Principal Investigator Basic Section 49060:Virology-related Except Principal Investigator Basic Section 49060:Virology-related / Medium-sized Section 58:Society medicine, nursing, and related fields / Virology
Keywords	Principal Investigator 重症化 / 宿主適応 / 新型コロナウイルス / RIG-I / SARS-CoV-2 / 抗ウイルス薬 / ウイルス学 / ウイルス複製 / ヒト適応性 / 宿主因子 / インフルエンザウイルス … More Except Principal Investigator … More 新興ウイルス / 重篤化機序 / 宿主適応 / 免疫応答 / 重症化機序 / RNA / 新興感染症 / 調査研究 / 進化動態 / ウイルスエコロジー / インフルエンザウイルス / 感染病態学 / 人獣共通感染症学 / ウイルス学 Less

Elucidation of the universal aggravation mechanism of emerging viruses focusing on unexplored short viral RNA
- Principal Investigator
  
  渡邊洋平
- Project Period (FY)
  2022 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 49060:Virology-related
- Research Institution
  Kyoto Prefectural University of Medicine
Elucidation of the mechanism of disease severity caused by SARS-CoV-2 focusing on the incompatibility between by virus and hostPrincipal Investigator
- Principal Investigator
  
  荒井泰葉
- Project Period (FY)
  2021 – 2022
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 49060:Virology-related
- Research Institution
  Kyoto Prefectural University of Medicine
アジア・アフリカの新興感染症ホットスポット域におけるウイルス進化動態の調査研究
- Principal Investigator
  
  渡邊洋平
- Project Period (FY)
  2020 – 2024
- Research Category
  
  Fund for the Promotion of Joint International Research (Fostering Joint International Research (B))
- Review Section
  
  Medium-sized Section 58:Society medicine, nursing, and related fields
- Research Institution
  Kyoto Prefectural University of Medicine
Investigation for novel antiviral lead compounds focusing on the host adaptation mechanism of influenza virusPrincipal Investigator
- Principal Investigator
  
  Arai Yasuha
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 49060:Virology-related
- Research Institution
  Kyoto Prefectural University of Medicine
Characterization of avian influenza virus variants isolated from infected patients
- Principal Investigator
  
  Watanabe Yohei
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Virology
- Research Institution
  Kyoto Prefectural University of Medicine

All 2023 2022 2021 2020 2019 2018 2017 2016 2015

All Journal Article Presentation

[Journal Article] Stimulation of interferon-β responses by aberrant SARS-CoV-2 small viral RNAs acting as retinoic acid-inducible gene-I agonists2023
- Author(s)
  Arai Yasuha、Yamanaka Itaru、Okamoto Toru、Isobe Ayana、Nakai Naomi、Kamimura Naoko、Suzuki Tatsuya、Daidoji Tomo、Ono Takao、Nakaya Takaaki、Matsumoto Kazuhiko、Okuzaki Daisuke、Watanabe Yohei
- Journal Title
  
  iScience
  
  Volume: 26 Issue: 1 Pages: 105742-105742
- DOI
  10.1016/j.isci.2022.105742
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K08510, KAKENHI-PROJECT-20KK0224, KAKENHI-PROJECT-21H03184, KAKENHI-PROJECT-20K21723, KAKENHI-PROJECT-21K15455, KAKENHI-PROJECT-23K24141, KAKENHI-PROJECT-23K27671
[Journal Article] ACE2 N-glycosylation modulates interactions with SARS-CoV-2 spike protein in a site-specific manner2022
- Author(s)
  Isobe Ayana、Arai Yasuha、Kuroda Daisuke、Okumura Nobuaki、Ono Takao、Ushiba Shota、Nakakita Shin-ichi、Daidoji Tomo、Suzuki Yasuo、Nakaya Takaaki、Matsumoto Kazuhiko、Watanabe Yohei
- Journal Title
  
  Communications Biology
  
  Volume: 5 Issue: 1 Pages: 1188-1188
- DOI
  10.1038/s42003-022-04170-6
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K08510, KAKENHI-PROJECT-20KK0224, KAKENHI-PROJECT-21H03184, KAKENHI-PROJECT-20K21723, KAKENHI-PROJECT-21K15455, KAKENHI-PROJECT-23K24141
[Journal Article] Double mutations in the H9N2 avian influenza virus PB2 gene act cooperatively to increase viral host adaptation and replication for human infections2021
- Author(s)
  Elgendy Emad Mohamed、Arai Yasuha、Kawashita Norihito、Isobe Ayana、Daidoji Tomo、Ibrahim Madiha Salah、Ono Takao、Takagi Tatsuya、Nakaya Takaaki、Matsumoto Kazuhiko、Watanabe Yohei
- Journal Title
  
  Journal of General Virology
  
  Volume: 102 Issue: 6 Pages: 1-17
- DOI
  10.1099/jgv.0.001612
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K08510, KAKENHI-PROJECT-20K21723, KAKENHI-PROJECT-20KK0199, KAKENHI-PROJECT-20KK0224
[Journal Article] H9N2 Influenza Virus Infections in Human Cells Require a Balance between Neuraminidase Sialidase Activity and Hemagglutinin Receptor Affinity2020
- Author(s)
  Arai Yasuha、Elgendy Emad Mohamed、Daidoji Tomo、Ibrahim Madiha Salah、Ono Takao、Sriwilaijaroen Nongluk、Suzuki Yasuo、Nakaya Takaaki、Matsumoto Kazuhiko、Watanabe Yohei
- Journal Title
  
  Journal of Virology
  
  Volume: 94 Issue: 18
- DOI
  10.1128/jvi.01210-20
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K21723, KAKENHI-PROJECT-20KK0224, KAKENHI-INTERNATIONAL-16K21723, KAKENHI-PUBLICLY-19H04841, KAKENHI-PROJECT-18K15171, KAKENHI-ORGANIZER-16H06429
[Journal Article] PA Mutations Inherited during Viral Evolution Act Cooperatively To Increase Replication of Contemporary H5N1 Influenza Virus with an Expanded Host Range2020
- Author(s)
  Arai Yasuha、Kawashita Norihito、Elgendy Emad Mohamed、Ibrahim Madiha Salah、Daidoji Tomo、Ono Takao、Takagi Tatsuya、Nakaya Takaaki、Matsumoto Kazuhiko、Watanabe Yohei
- Journal Title
  
  Journal of Virology
  
  Volume: 95 Issue: 1
- DOI
  10.1128/jvi.01582-20
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K21723, KAKENHI-PROJECT-20KK0224, KAKENHI-INTERNATIONAL-16K21723, KAKENHI-PUBLICLY-19H04841, KAKENHI-PROJECT-18K15171, KAKENHI-ORGANIZER-16H06429
[Journal Article] “Genetic tuning” of avian influenza virus host adaptation from birds to humans2020
- Author(s)
  Arai Yasuha、Watanabe Yohei
- Journal Title
  
  Biosafety and Health
  
  Volume: Online ahead of print Issue: 2 Pages: 1-3
- DOI
  10.1016/j.bsheal.2020.11.006
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K21723, KAKENHI-PROJECT-20KK0224, KAKENHI-INTERNATIONAL-16K21723, KAKENHI-PUBLICLY-19H04841, KAKENHI-PROJECT-18K15171, KAKENHI-ORGANIZER-16H06429
[Journal Article] Genetic Compatibility of Reassortants between Avian H5N1 and H9N2 Influenza Viruses with Higher Pathogenicity in Mammals.2019
- Author(s)
  Arai Y, Ibrahim MS, Elgendy EM, Daidoji T, Ono T, Suzuki Y, Nakaya T, Matsumoto K, Watanabe Y.
- Journal Title
  
  J Virol.
  
  Volume: 93(4) Issue: 4
- DOI
  10.1128/jvi.01969-18
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K15171, KAKENHI-PROJECT-15H05295, KAKENHI-PROJECT-18H03040
[Journal Article] PB2 mutations arising during H9N2 influenza evolution in the Middle East confer enhanced replication and growth in mammals.2019
- Author(s)
  Arai Y, Kawashita N, Ibrahim MS, Elgendy EM, Daidoji T, Ono T, Takagi T, Nakaya T, Matsumoto K, Watanabe Y.
- Journal Title
  
  PLOS Pathogens
  
  Volume: 15(7) Issue: 7 Pages: e1007919-e1007919
- DOI
  10.1371/journal.ppat.1007919
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K15171, KAKENHI-INTERNATIONAL-16K21723, KAKENHI-ORGANIZER-16H06429, KAKENHI-PUBLICLY-19H04841, KAKENHI-PROJECT-15H05295, KAKENHI-PROJECT-18H03040, KAKENHI-PROJECT-18K14107
[Journal Article] Characterization of H5N1 influenza virus quasispecies with adaptive hemagglutinin mutations from single-virus infections of human airway cells2018
- Author(s)
  1.Watanabe Y**, Arai Y, Kawashita N, Ibrahim MS, Elgendy EM, Daidoji T, Kajikawa J, Hiramatsu H, Sriwilaijaroen N, Ono T, Takagi T, Takahashi K, Shioda T, Matsumoto K, Suzuki Y, Nakaya T
- Journal Title
  
  J Virol.
  
  Volume: 印刷中 Issue: 11
- DOI
  10.1128/jvi.02004-17
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H05287, KAKENHI-PROJECT-15H05295, KAKENHI-PROJECT-16H05194, KAKENHI-PROJECT-15K08497, KAKENHI-PROJECT-15K09576, KAKENHI-PROJECT-18K15171
[Journal Article] Multiple polymerase gene mutations for human adaptation occurring in Asian H5N1 influenza virus clinical isolates2018
- Author(s)
  Arai Y, Kawashita N, Hotta K, Hoang PVM, Nguyen HLK, Nguyen TC, Vuong CD, Le TT, Le MTQ, Soda K, Ibrahim MS, Daidoji T, Takagi T, Shioda T, Nakaya T, Ito T, Hasebe F, Watanabe Y.
- Journal Title
  
  Sci Rep.
  
  Volume: 8 Issue: 1 Pages: 13066-13066
- DOI
  10.1038/s41598-018-31397-3
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K15171, KAKENHI-PROJECT-15H05295
[Journal Article] Unique Infectious Strategy of H5N1 Avian Influenza Virus Is Governed by the Acid-Destabilized Property of Hemagglutinin.2017
- Author(s)
  Daidoji T**, Watanabe Y, Arai Y, Kajikawa J, Hirose R, Nakaya T
- Journal Title
  
  Viral Immunol.
  
  Volume: 30 Issue: 6 Pages: 398-407
- DOI
  10.1089/vim.2017.0020
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15H05287, KAKENHI-PROJECT-15H05295, KAKENHI-PROJECT-15K08497, KAKENHI-PROJECT-15K09576
[Journal Article] Identification of polymerase gene mutations that affect viral replication in H5N1 influenza viruses isolated from pigeons.2017
- Author(s)
  Elgendy EM, Arai Y, Kawashita N, Daidoji T, Takagi T, Ibrahim MS, Nakaya T, Watanabe Y
- Journal Title
  
  J Gen Virol.
  
  Volume: 98 Issue: 1 Pages: 6-17
- DOI
  10.1099/jgv.0.000674
- Peer Reviewed / Acknowledgement Compliant / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H05287, KAKENHI-PROJECT-15H05295, KAKENHI-PROJECT-16J00589, KAKENHI-PROJECT-15K08497, KAKENHI-PROJECT-15K09576
[Journal Article] Novel Polymerase Gene Mutations for Human Adaptation in Clinical Isolates of Avian H5N1 Influenza Viruses2016
- Author(s)
  Arai Y, Kawashita N, Daidoji T, Ibrahim MS, El-Gendy EM, Takagi T, Takahashi K, Suzuki Y, Ikuta K, Nakaya T, Shioda T, Watanabe Y
- Journal Title
  
  PLoS Pathog.
  
  Volume: 12 Issue: 4 Pages: e1005583-e1005583
- DOI
  10.1371/journal.ppat.1005583
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K09576, KAKENHI-PROJECT-15H05295, KAKENHI-PROJECT-16J00589, KAKENHI-PROJECT-15K08497
[Journal Article] Long-term detection of seasonal influenza RNA in faeces and intestine.2016
- Author(s)
  Hirose R, Daidoji T, Naito Y, Watanabe Y, Arai Y, Oda T, Konishi H, Yamawaki M, Itoh Y, Nakaya T.
- Journal Title
  
  Clin Microbiol Infect
  
  Volume: 22 Issue: 9 Pages: 813-813
- DOI
  10.1016/j.cmi.2016.06.015
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-15H05287, KAKENHI-PROJECT-15H05295, KAKENHI-PROJECT-15K08497, KAKENHI-PROJECT-15K09576
[Journal Article] Genetic characterization of highly pathogenic avian influenza H5N1 viruses isolated from naturally infected pigeons in Egypt2016
- Author(s)
  Elgendy EM, Watanabe Y, Daidoji T, Arai Y, Ikuta K, Ibrahim MS, Nakaya T
- Journal Title
  
  Virus Genes
  
  Volume: 52 Issue: 6 Pages: 867-871
- DOI
  10.1007/s11262-016-1369-z
- Peer Reviewed / Acknowledgement Compliant / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H05295, KAKENHI-PROJECT-16J00589, KAKENHI-PROJECT-15K08497, KAKENHI-PROJECT-15K09576
[Journal Article] Characterization of H5N1 Influenza Virus Variants with Hemagglutinin Mutations Isolated from Patients.2015
- Author(s)
  1.Watanabe Y, Arai Y, Daidoji T, Kawashita N, Ibrahim MS, El-Gendy E, Hiramatsu H, Kubota-Kokestu R, Takagi T, Murata T, Takahashi K, Okuno Y, Nakaya T, Suzuki Y, Ikuta K.
- Journal Title
  
  mBio
  
  Volume: 6 Issue: 2
- DOI
  10.1128/mbio.00081-15
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-24390146, KAKENHI-PROJECT-24591480, KAKENHI-PROJECT-15K08497, KAKENHI-PROJECT-15H05287, KAKENHI-PROJECT-15H05295, KAKENHI-PROJECT-23406017
[Presentation] Stimulation of IFN-beta responses by aberrant SARS-CoV-2 small viral RNAs2022
- Author(s)
  Arai Y, Yamanaka I, Okamoto T, Isobe A, Nakai N, Kamimura N, Suzuki T, Daidoj T, Nakaya T, Okuzaki D, Watanabe Y
- Organizer
  第23回日本RNA学会年会
- Data Source
  KAKENHI-PROJECT-23K24141
[Presentation] Stimulation of IFN-beta responses by aberrant SARS-CoV-2 small viral RNAs2022
- Author(s)
  Arai Y, Yamanaka I, Okamoto T, Isobe A, Nakai N, Kamimura N, Suzuki T, Daidoj T, Nakaya T, Okuzaki D, Watanabe Y
- Organizer
  第23回日本RNA学会年会（英語発表）
- Data Source
  KAKENHI-PROJECT-20KK0224
[Presentation] ACE2 N-glycosylation modulates interactions with SARS-CoV-2 spike protein in a site-specific manner2022
- Author(s)
  Isobe A, Arai Y, Okumura N, Ono T, Nakakita S, Daidoji T, Suzuki Y, Nakaya T, Matsumoto K, Watanabe Y
- Organizer
  第69回日本ウイルス学会学術集会
- Data Source
  KAKENHI-PROJECT-23K24141
[Presentation] Stimulation of IFN-beta responses by aberrant SARS-CoV-2 small viral RNAs2022
- Author(s)
  Yasuha Arai, Itaru Yamanaka, Toru Okamoto, Ayana Isobe, Naomi Nakai, Naoko Kamimura, Tatsuya Suzuki, Tomo Daidoji, Takaaki Nakaya, Daisuke Okuzaki, Yohei Watanabe
- Organizer
  日本RNA学会
- Data Source
  KAKENHI-PROJECT-21K15455
[Presentation] ACE2 N-glycosylation modulates interactions with SARS-CoV-2 spike protein in a site-specific manner2022
- Author(s)
  Isobe A, Arai Y, Okumura N, Ono T, Nakakita S, Daidoji T, Suzuki Y, Nakaya T, Matsumoto K, Watanabe Y
- Organizer
  第69回日本ウイルス学会学術集会
- Data Source
  KAKENHI-PROJECT-20KK0224
[Presentation] ACE2 N-glycosylation modulates interactions with SARS-CoV-2 spike protein in a site-specific manner2022
- Author(s)
  Ayana Isobe, Yasuha Arai, Nobuaki Okumura, Takao Ono, Shin-ichi Nakakita, Tomo Daidoji, Yasuo Suzuki, Takaaki Nakaya, Kazuhiko Matsumoto, Yohei Watanabe
- Organizer
  日本ウイルス学会
- Data Source
  KAKENHI-PROJECT-21K15455
[Presentation] 近年中国で優勢に流行するH9N2亜型鳥インフルエンザウイルスのPB2遺伝子に選択された同時変異群はヒト適応性を高く変化させている2021
- Author(s)
  荒井泰葉、Emad M. Elgendy, 川下理日人、磯邉綾菜、大道寺智、中屋隆明、渡邊洋平
- Organizer
  第68回日本ウイルス学会学術集会
- Data Source
  KAKENHI-PROJECT-20KK0224
[Presentation] Accumulation of PA mutations in Egyptian H5N1 viruses during viral evolution conferred the increased replication ability.2019
- Author(s)
  Yasuha Arai, Emad M. Elgendy, Tomo Daidoji, Madiha S. Ibrahim, Takaaki Nakaya, Yohei Watanabe.
- Organizer
  第67回日本ウイルス学会学術集会
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K15171
[Presentation] Evaluation of avian influenza virus infection in human tracheal epithelial cell clones2018
- Author(s)
  Tomo Daidoji, Junichi Kajikawa, Yohei Watanabe, Yasuha Arai, Takaaki Nakaya.
- Organizer
  第66回日本ウイルス学会学術集会
- Data Source
  KAKENHI-PROJECT-18K15171
[Presentation] GENETIC COMPATIBILITY AND VIRULENCE OF REASSORTANTS DERIVED FROM H9N2 AND H5N1 AVIAN INFLUENZA VIRUSES CO-CIRCULATING IN EGYPT2018
- Author(s)
  Yasuha Arai*, Madiha Ibrahim, Takaaki Nakaya, Yohei Watanabe.
- Organizer
  Negative Strand Virus 2018
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K15171
[Presentation] Evolutionally dynamics of Egyptian H9N2 avian influenza virus in nature conferred enhanced replication ability in humans.2018
- Author(s)
  Yasuha Arai*, Madiha S. Ibrahim, Emad M. Elgendy, Tomo Daidoji, Takaaki Nakaya, Yohei Watanabe.
- Organizer
  第66回日本ウイルス学会学術集会
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K15171
[Presentation] Novel polymerase gene mutations for human adaptation in clinical isolates of Avian H5N1 influenza virus in Asia.2017
- Author(s)
  Arai Y, Kawashita N, Hotta K, Hoang MPV, Nguyen KHL, Nguyen TC, Vuong CD, Le MQ, Soda K, Kajikawa J, Daidoji T, Nakaya T, Takagi T, Ito T, Hasebe H, Shioda T, Watanabe Y.
- Organizer
  第65回日本ウイルス学会学術集会
- Data Source
  KAKENHI-PROJECT-15K08497
[Presentation] Evaluation of avian influenza virus infection in differentiated airway epithelial cells.2017
- Author(s)
  Daidoji T, Noguchi M, Kajikawa J, Watanabe Y, Arai Y, Hirose R, Morimoto M, Nakaya T.
- Organizer
  第65回日本ウイルス学会学術集会
- Data Source
  KAKENHI-PROJECT-15K08497
[Presentation] Mechanism of seasonal influenza virus persistence in human digestive tract: Mucus protects virions from acid and digestive juices.2017
- Author(s)
  Nakaya T, Hirose R, Daidoji T, Naito Y, Watanabe Y, Arai Y, Kawada K, Kajikawa J, Yamawaki M, Itoh Y.
- Organizer
  第65回日本ウイルス学会学術集会
- Data Source
  KAKENHI-PROJECT-15K08497
[Presentation] Characterization of H5N1 influenza virus with HA mutations diversified in human airway epithelial cells as minor variants.2017
- Author(s)
  Watanabe Y, Arai Y, Kawashita N, Daidoji T, Elgendy EM, Ibrahim MS, Kajikawa J, Hiramatsu H, Takagi T, Takahashi K, Shioda T, Suzuki Y, Nakaya T.
- Organizer
  第65回日本ウイルス学会学術集会
- Data Source
  KAKENHI-PROJECT-15K08497
[Presentation] Establishment of immortalized cell clones from human tracheal epithelial cells and their different susceptibility to influenza viruses.2017
- Author(s)
  Kajikawa J, Daidoji T, Watanabe Y, Arai Y, Hirose R, Nakaya T.
- Organizer
  第65回日本ウイルス学会学術集会
- Data Source
  KAKENHI-PROJECT-15K08497
[Presentation] Hemagglutinin acid stability and viral infection in H7 influenza virus2016
- Author(s)
  Daidoji T, Elgendy EM, Watanabe Y, Arai Y, Ibrahim MS, Ikuta K, Nakaya T
- Organizer
  第64回日本ウイルス学会学術集会
- Place of Presentation
  札幌
- Year and Date
  2016-10-23
- Data Source
  KAKENHI-PROJECT-15K08497
[Presentation] Characterization of H5N1 influenza virus variants with HA mutations selected during the viral replication in human airway epithelial cells2016
- Author(s)
  Watanabe Y, Arai Y, Daidoji T, Elgendy EM, Ibrahim MS, Takahashi K, Shioda T, Ikuta　K, Suzuki Y, Nakaya T
- Organizer
  第64回日本ウイルス学会学術集会
- Place of Presentation
  札幌
- Year and Date
  2016-10-23
- Data Source
  KAKENHI-PROJECT-15K08497
[Presentation] Identification of unique mutations that influence the polymerase activity of H5N1 avian influenza virus isolated from pigeons2016
- Author(s)
  Elgendy EM, Arai Y, Ibrahim MS, Daidoji T, Ikuta K, Nakaya T, Watanabe Y
- Organizer
  第64回日本ウイルス学会学術集会
- Place of Presentation
  札幌
- Year and Date
  2016-10-23
- Data Source
  KAKENHI-PROJECT-15K08497
[Presentation] Novel polymerase gene mutations for human adaptation in clinical isolates of avian H5N1 influenza viruses2016
- Author(s)
  Arai Y, Kawashita N, Daidoji T, Ibrahim MS, Takayashi K, Suzuki Y, Nakaya T, Shioda T, Ikuta K, Watanabe Y
- Organizer
  第64回日本ウイルス学会学術集会
- Place of Presentation
  札幌
- Year and Date
  2016-10-23
- Data Source
  KAKENHI-PROJECT-15K08497
[Presentation] Genetic characterization of H5N1 avian influenza virus from pigeon in Egypt 20092015
- Author(s)
  Emad Elgendy, Madiha S. Ibrahim, Arai Yasuha, Tomo Daidoji, Yohei Watanabe, Takaaki Nakaya
- Organizer
  第63回日本ウイルス学会学術集会
- Place of Presentation
  福岡
- Year and Date
  2015-11-22
- Data Source
  KAKENHI-PROJECT-15K08497
[Presentation] Identification of human adaptive mutations in the polymerase complex of H5N1 avian influenza virus in Egypt2015
- Author(s)
  Yasuha Arai, Tomo Didoji, Madiha S. Ibrahim, Kazuo Takahashi, Yasuo Suzuki, Takaaki Nakaya, Tatsuo Shioda, Kazuyoshi Ikuta, Yohei Watanabe
- Organizer
  第63回日本ウイルス学会学術集会
- Place of Presentation
  福岡
- Year and Date
  2015-11-22
- Data Source
  KAKENHI-PROJECT-15K08497
[Presentation] Genetic diversification of H5N1 avian influenza virus variants during replication in human airway epithelial cells2015
- Author(s)
  Yohei Watanabe, Yasuha Arai, Tomo Daidoji, Madiha S Ibrahim, Emad Elgendy, Kazuo Takahashi, Yasuo Suzuki, Tatsuo Shioda, Kazuyoshi Ikuta, Takaaki Nakaya
- Organizer
  第63回日本ウイルス学会学術集会
- Place of Presentation
  福岡
- Year and Date
  2015-11-22
- Data Source
  KAKENHI-PROJECT-15K08497

1. Watanabe Yohei (50452462)

# of Collaborated Projects: 3 results

# of Collaborated Products: 22 results
2. 鈴木康夫 (00046278)

# of Collaborated Projects: 1 results

# of Collaborated Products: 5 results
3. 大道寺智 (80432433)

# of Collaborated Projects: 1 results

# of Collaborated Products: 20 results
4. 小川晴子 (10400079)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
5. 武田洋平 (30804447)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. NAKAYA Takaaki

# of Collaborated Projects: 0 results

# of Collaborated Products: 6 results
7. Ibrahim Madiha S.

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results

ARAI Yasuha 荒井 泰葉

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Elucidation of the universal aggravation mechanism of emerging viruses focusing on unexplored short viral RNA

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Elucidation of the mechanism of disease severity caused by SARS-CoV-2 focusing on the incompatibility between by virus and hostPrincipal Investigator

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アジア・アフリカの新興感染症ホットスポット域におけるウイルス進化動態の調査研究

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Investigation for novel antiviral lead compounds focusing on the host adaptation mechanism of influenza virusPrincipal Investigator

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Characterization of avian influenza virus variants isolated from infected patients

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[Journal Article] Stimulation of interferon-β responses by aberrant SARS-CoV-2 small viral RNAs acting as retinoic acid-inducible gene-I agonists2023

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[Journal Article] ACE2 N-glycosylation modulates interactions with SARS-CoV-2 spike protein in a site-specific manner2022

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[Journal Article] Double mutations in the H9N2 avian influenza virus PB2 gene act cooperatively to increase viral host adaptation and replication for human infections2021

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[Journal Article] H9N2 Influenza Virus Infections in Human Cells Require a Balance between Neuraminidase Sialidase Activity and Hemagglutinin Receptor Affinity2020

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[Journal Article] PA Mutations Inherited during Viral Evolution Act Cooperatively To Increase Replication of Contemporary H5N1 Influenza Virus with an Expanded Host Range2020

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[Journal Article] “Genetic tuning” of avian influenza virus host adaptation from birds to humans2020

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[Journal Article] Genetic Compatibility of Reassortants between Avian H5N1 and H9N2 Influenza Viruses with Higher Pathogenicity in Mammals.2019

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[Journal Article] PB2 mutations arising during H9N2 influenza evolution in the Middle East confer enhanced replication and growth in mammals.2019

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[Journal Article] Characterization of H5N1 influenza virus quasispecies with adaptive hemagglutinin mutations from single-virus infections of human airway cells2018

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[Journal Article] Multiple polymerase gene mutations for human adaptation occurring in Asian H5N1 influenza virus clinical isolates2018

ARAI Yasuha 荒井泰葉