Abe Yoshifumi 阿部欣史

Researcher Number	80802826
Other IDs
Affiliation (Current)	2025: 慶應義塾大学, 医学部(信濃町), 講師
Affiliation (based on the past Project Information) *help	2023: 慶應義塾大学, 医学部(信濃町), 講師 2021 – 2022: 慶應義塾大学, 医学部(信濃町), 助教 2019 – 2020: 慶應義塾大学, 医学部(信濃町), 研究員
Review Section/Research Field	Principal Investigator Basic Section 46020:Anatomy and histopathology of nervous system-related / Basic Section 46030:Function of nervous system-related
Keywords	Principal Investigator 脳体積 / 線条体 / 遅発性ジスキネジア / L-DOPA誘導性ジスキネジ / 黒質 / ドパミン / GABA小胞トランスポーター / GABA / VGAT / 淡蒼球 … More / 遅発性ジスキネジア / L-DOPA誘導性ジスキネジア / 側坐核 / ドパミン受容体 / 脳深部刺激療法 / 背側線条体 / D2-MSN / D1-MSN / 光遺伝学 / VBM / 拡散MRI / 前頭葉 / シナプス / MRI / DBS / 薬物依存 Less

Common Mechanism of Dyskinesia Onset between Antipsychotic Drugs and Parkinson's Disease TreatmentsPrincipal Investigator
- Principal Investigator
  
  Abe Yoshifumi
- Project Period (FY)
  2022 – 2023
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 46020:Anatomy and histopathology of nervous system-related
- Research Institution
  Keio University
Understanding the mechanism of deep brain stimulation therapy using diffusion MRIPrincipal Investigator
- Principal Investigator
  
  Abe Yoshifumi
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 46030:Function of nervous system-related
- Research Institution
  Keio University

All 2024 2023 2022 2021 2020 2019

All Journal Article Presentation

[Journal Article] Neurogenesis-independent mechanisms of MRI-detectable hippocampal volume increase following electroconvulsive stimulation2024
- Author(s)
  Abe Yoshifumi、Yokoyama Kiichi、Kato Tomonobu、Yagishita Sho、Tanaka Kenji F.、Takamiya Akihiro
- Journal Title
  
  Neuropsychopharmacology
  
  Volume: - Issue: 8 Pages: 1236-1245
- DOI
  10.1038/s41386-023-01791-1
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K15215
[Journal Article] Shared GABA transmission pathology in dopamine agonist- and antagonist-induced dyskinesia2023
- Author(s)
  Abe Yoshifumi、Yagishita Sho、Sano Hiromi、Sugiura Yuki、Dantsuji Masanori、Suzuki Toru、Mochizuki Ayako、Yoshimaru Daisuke、Hata Junichi、Matsumoto Mami、Taira Shu、Takeuchi Hiroyoshi、Okano Hideyuki、Ohno Nobuhiko、Suematsu Makoto、Inoue Tomio、Nambu Atsushi、Watanabe Masahiko、Tanaka Kenji F.
- Journal Title
  
  Cell Reports Medicine
  
  Volume: 4 Issue: 10 Pages: 101208-101208
- DOI
  10.1016/j.xcrm.2023.101208
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K18951, KAKENHI-PROJECT-23K15966, KAKENHI-PROJECT-19KK0193, KAKENHI-PROJECT-21K09834, KAKENHI-PROJECT-21K07257, KAKENHI-PROJECT-21K19614, KAKENHI-PROJECT-22K15202, KAKENHI-PROJECT-22K15215, KAKENHI-PUBLICLY-22H04790, KAKENHI-PLANNED-21H05176, KAKENHI-PROJECT-22H04926, KAKENHI-PROJECT-23K21178
[Journal Article] Direct Impact of Motor Cortical Stimulation on the Blood Oxygen-level Dependent Response in Rats2021
- Author(s)
  Xin Zonghao、Abe Yoshifumi、Liu Shuang、Tanaka Kenji F.、Hosomi Koichi、Saitoh Youichi、Sekino Masaki
- Journal Title
  
  MRMS
  
  Volume: 20 Issue: 1 Pages: 83-90
- DOI
  10.2463/mrms.mp.2019-0156
- NAID
  130007993616
- ISSN
  1347-3182, 1880-2206
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K16298, KAKENHI-PUBLICLY-19H05027, KAKENHI-PLANNED-20H05896, KAKENHI-PROJECT-18J00922, KAKENHI-PROJECT-18K08993
[Journal Article] Optical manipulation of local cerebral blood flow in the deep brain of freely moving mice2021
- Author(s)
  Abe Yoshifumi、Kwon Soojin、Oishi Mitsuhiro、Unekawa Miyuki、Takata Norio、Seki Fumiko、Koyama Ryuta、Abe Manabu、Sakimura Kenji、Masamoto Kazuto、Tomita Yutaka、Okano Hideyuki、Mushiake Hajime、Tanaka Kenji F.
- Journal Title
  
  Cell Reports
  
  Volume: 36 Issue: 4 Pages: 109427-109427
- DOI
  10.1016/j.celrep.2021.109427
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K06944, KAKENHI-PROJECT-19K16298, KAKENHI-PUBLICLY-21H00212, KAKENHI-PROJECT-19H03337, KAKENHI-PROJECT-20K06929, KAKENHI-PROJECT-21K06443, KAKENHI-PROJECT-19K16031, KAKENHI-PLANNED-20H05896
[Journal Article] Oligodendrocytic Na+-K+-Cl- co-transporter 1 activity facilitates axonal conduction and restores plasticity in the adult mouse brain2021
- Author(s)
  Yamazaki Yoshihiko、Abe Yoshifumi、Fujii Satoshi、Tanaka Kenji F.
- Journal Title
  
  Nature Communications
  
  Volume: 12 Issue: 1 Pages: 5146-5146
- DOI
  10.1038/s41467-021-25488-5
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K16298, KAKENHI-PLANNED-20H05896
[Journal Article] Chd8 mutation in oligodendrocytes alters microstructure and functional connectivity in the mouse brain.2020
- Author(s)
  Kawamura A, Abe Y, Seki F, Katayama Y, Nishiyama M, Takata N, Tanaka KF, Okano H, Nakayama KI.
- Journal Title
  
  Molecular Brain
  
  Volume: 13 Pages: 1-15
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K16298
[Journal Article] Diffusion functional MRI reveals global brain network functional abnormalities driven by targeted local activity in a neuropsychiatric disease mouse model2020
- Author(s)
  Abe Yoshifumi、Takata Norio、Sakai Yuki、Hamada Hiro Taiyo、Hiraoka Yuichi、Aida Tomomi、Tanaka Kohichi、Bihan Denis Le、Doya Kenji、Tanaka Kenji F
- Journal Title
  
  NeuroImage
  
  Volume: 223 Pages: 117318-117318
- DOI
  10.1016/j.neuroimage.2020.117318
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K06944, KAKENHI-PROJECT-19K16298, KAKENHI-PUBLICLY-19H05027, KAKENHI-ORGANIZER-20H05894, KAKENHI-PLANNED-20H05896, KAKENHI-PROJECT-18J00922, KAKENHI-PLANNED-16H06563
[Journal Article] Spatial contribution of hippocampal BOLD activation in high-resolution fMRI2019
- Author(s)
  Abe Yoshifumi、Tsurugizawa Tomokazu、Le Bihan Denis、Ciobanu Luisa
- Journal Title
  
  Scientific Reports
  
  Volume: 9 Issue: 1 Pages: 3152-3152
- DOI
  10.1038/s41598-019-39614-3
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18J00922, KAKENHI-PROJECT-19K16298
[Journal Article] Correlative study using structural MRI and super-resolution microscopy to detect structural alterations induced by long-term optogenetic stimulation of striatal medium spiny neurons2019
- Author(s)
  Abe Yoshifumi、Komaki Yuji、Seki Fumiko、Shibata Shinsuke、Okano Hideyuki、Tanaka Kenji F.
- Journal Title
  
  Neurochemistry International
  
  Volume: 125 Pages: 163-174
- DOI
  10.1016/j.neuint.2019.02.017
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K10842, KAKENHI-PROJECT-15H03123, KAKENHI-PROJECT-18J00922, KAKENHI-PROJECT-19K16298, KAKENHI-PUBLICLY-19H05027
[Journal Article] Region- and cell type-specific facilitation of synaptic function at destination synapses induced by oligodendrocyte depolarization2019
- Author(s)
  Yamazaki Y, Abe Y, Shibata S, Shindo T, Fujii S, Ikenaka K, Tanaka KF
- Journal Title
  
  The Journal of Neuroscience
  
  Volume: - Issue: 21 Pages: 4036-4050
- DOI
  10.1523/jneurosci.1619-18.2019
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K01943, KAKENHI-PROJECT-15H03123, KAKENHI-PROJECT-19K16298, KAKENHI-PUBLICLY-19H05027, KAKENHI-PROJECT-18J00922
[Presentation] マウスMRI計測によって可視化できる脳体積変化を細胞・分子レベルで読み解く2022
- Author(s)
  阿部欣史
- Organizer
  2022年度生理学研究所研究会多次元脳形態研究会
- Invited
- Data Source
  KAKENHI-PROJECT-22K15215
[Presentation] L-DOPA誘発性ジスキネジアでなぜ淡蒼球体積が増加するのか2021
- Author(s)
  阿部欣史
- Organizer
  第64回日本神経化学会大会
- Data Source
  KAKENHI-PROJECT-19K16298
[Presentation] オプトジェネティクスを用いた局所脳血流の操作技術2020
- Author(s)
  阿部欣史
- Organizer
  第63回日本神化学学大会
- Data Source
  KAKENHI-PROJECT-19K16298
[Presentation] Diffusion functional MRI characterizes dynamical brain function in a neuropsychiatric disease model mouse2020
- Author(s)
  阿部欣史
- Organizer
  ISMRM 27th Annual Meeting
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K16298
[Presentation] 構造解析から見る神経―オリゴデンドロサイトの相互作用について2019
- Author(s)
  阿部欣史
- Organizer
  次世代薬理学セミナー
- Invited
- Data Source
  KAKENHI-PROJECT-19K16298
[Presentation] DTI found structural altercations induced by long-term optogenetics stimulation of striatal medium spiny neurons2019
- Author(s)
  Yoshifumi Abe
- Organizer
  The International Society of Neurochemistry (ISN) and the American Society of Neurochemistry (ASN) 2019
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K16298
[Presentation] 線条体神経細胞への長期的な光刺激によって起こる有髄神経軸索の構造解析2019
- Author(s)
  阿部欣史
- Organizer
  第62回日本神経化学会
- Data Source
  KAKENHI-PROJECT-19K16298

1. KOMAKI Yuji

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
2. 壇辻昌典

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
3. 山崎良彦

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
4. 高田則雄

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results

Abe Yoshifumi 阿部 欣史

Research Projects

Research Products

Co-Researchers

Common Mechanism of Dyskinesia Onset between Antipsychotic Drugs and Parkinson's Disease TreatmentsPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Understanding the mechanism of deep brain stimulation therapy using diffusion MRIPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

[Journal Article] Neurogenesis-independent mechanisms of MRI-detectable hippocampal volume increase following electroconvulsive stimulation2024

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Shared GABA transmission pathology in dopamine agonist- and antagonist-induced dyskinesia2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Direct Impact of Motor Cortical Stimulation on the Blood Oxygen-level Dependent Response in Rats2021

Author(s)

Journal Title

DOI

NAID

ISSN

Language

Data Source

[Journal Article] Optical manipulation of local cerebral blood flow in the deep brain of freely moving mice2021

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Oligodendrocytic Na+-K+-Cl- co-transporter 1 activity facilitates axonal conduction and restores plasticity in the adult mouse brain2021

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Chd8 mutation in oligodendrocytes alters microstructure and functional connectivity in the mouse brain.2020

Author(s)

Journal Title

Data Source

[Journal Article] Diffusion functional MRI reveals global brain network functional abnormalities driven by targeted local activity in a neuropsychiatric disease mouse model2020

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Spatial contribution of hippocampal BOLD activation in high-resolution fMRI2019

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Correlative study using structural MRI and super-resolution microscopy to detect structural alterations induced by long-term optogenetic stimulation of striatal medium spiny neurons2019

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Region- and cell type-specific facilitation of synaptic function at destination synapses induced by oligodendrocyte depolarization2019

Author(s)

Journal Title

DOI

Data Source

[Presentation] マウスMRI計測によって可視化できる脳体積変化を細胞・分子レベルで読み解く2022

Author(s)

Organizer

Data Source

[Presentation] L-DOPA誘発性ジスキネジアでなぜ淡蒼球体積が増加するのか2021

Author(s)

Organizer

Data Source

[Presentation] オプトジェネティクスを用いた局所脳血流の操作技術2020

Author(s)

Organizer

Data Source

Abe Yoshifumi 阿部欣史