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KATO HIDEAKI  加藤 英明

… Alternative Names

Kato Hideaki  加藤 英明

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Researcher Number 80805961
Other IDs
  • ORCIDhttps://orcid.org/0000-0002-1941-5535
Affiliation (Current) 2025: 東京大学, 先端科学技術研究センター, 教授
Affiliation (based on the past Project Information) *help 2023 – 2025: 東京大学, 先端科学技術研究センター, 教授
2019 – 2023: 東京大学, 大学院総合文化研究科, 准教授
Review Section/Research Field
Principal Investigator
Transformative Research Areas, Section (III) / Medium-sized Section 43:Biology at molecular to cellular levels, and related fields / Basic Section 43020:Structural biochemistry-related
Except Principal Investigator
Medium-sized Section 40:Forestry and forest products science, applied aquatic science, and related fields / Medium-sized Section 47:Pharmaceutical sciences and related fields / Transformative Research Areas, Section (III) / Biological Sciences
Keywords
Principal Investigator
クライオ電子顕微鏡 / 膜タンパク質 / 構造生物学 / GPCR / 光受容体 / 光遺伝学 / ロドプシン / センサー / ツール開発 / 神経科学 … More / タンパク質工学 / 神経調節因子 / ダイナミクス / 微生物型ロドプシン / 創薬 / アレスチン / Gタンパク質 / ニューロテンシン受容体 … More
Except Principal Investigator
真核微生物 / 光受容 / ロドプシン / 微生物型ロドプシン / トランスクリプトーム / メタゲノム / 光受容体 / 海洋微生物 / DREADD / G12 / GPCR / 死認識 / 社会性神経科学 / X線 / 蛋白質 / X線 / 電子顕微鏡 / 生物物理 Less
  • Research Projects

    (9 results)
  • Research Products

    (26 results)
  • Co-Researchers

    (21 People)
  •  局所pHシグナルの人為的操作・計測技術の開発Principal Investigator

    • Principal Investigator
      加藤 英明
    • Project Period (FY)
      2025 – 2029
    • Research Category
      Grant-in-Aid for Transformative Research Areas (A)
    • Review Section
      Transformative Research Areas, Section (III)
    • Research Institution
      The University of Tokyo
  •  The analysis of structural dynamics of microbial rhodopsinsPrincipal Investigator

    • Principal Investigator
      加藤 英明
    • Project Period (FY)
      2022 – 2026
    • Research Category
      Grant-in-Aid for Scientific Research (A)
    • Review Section
      Medium-sized Section 43:Biology at molecular to cellular levels, and related fields
    • Research Institution
      The University of Tokyo
  •  Structural and functional analysis of novel transporter-type rhodopsinPrincipal Investigator

    • Principal Investigator
      加藤 英明
    • Project Period (FY)
      2022 – 2024
    • Research Category
      Grant-in-Aid for Challenging Research (Exploratory)
    • Review Section
      Medium-sized Section 43:Biology at molecular to cellular levels, and related fields
    • Research Institution
      The University of Tokyo
  •  The engineering of the novel imaging tools for neuromodulatorsPrincipal Investigator

    • Principal Investigator
      Kato Hideaki
    • Project Period (FY)
      2021 – 2023
    • Research Category
      Grant-in-Aid for Transformative Research Areas (B)
    • Review Section
      Transformative Research Areas, Section (III)
    • Research Institution
      The University of Tokyo
  •  Neural representation of "Death" (general affairs)

    • Principal Investigator
      Okuyama Teruhiro
    • Project Period (FY)
      2021 – 2023
    • Research Category
      Grant-in-Aid for Transformative Research Areas (B)
    • Review Section
      Transformative Research Areas, Section (III)
    • Research Institution
      The University of Tokyo
  •  Manipulation of G12/13 signaling and and drug development strategy

    • Principal Investigator
      井上 飛鳥
    • Project Period (FY)
      2021 – 2024
    • Research Category
      Grant-in-Aid for Scientific Research (A)
    • Review Section
      Medium-sized Section 47:Pharmaceutical sciences and related fields
    • Research Institution
      Tohoku University
  •  Enzyme-Type Rhodopsins: Unveiling the Role of Light-Activated Enzymes to Illuminate New Microbial Ecosystems

    • Principal Investigator
      Yoshizawa Susumu
    • Project Period (FY)
      2021 – 2023
    • Research Category
      Grant-in-Aid for Challenging Research (Exploratory)
    • Review Section
      Medium-sized Section 40:Forestry and forest products science, applied aquatic science, and related fields
    • Research Institution
      The University of Tokyo
  •  Structural analysis of NTSR1-G-protein complexesPrincipal Investigator

    • Principal Investigator
      KATO Hideaki
    • Project Period (FY)
      2019 – 2021
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Review Section
      Basic Section 43020:Structural biochemistry-related
    • Research Institution
      The University of Tokyo
  •  Molecular mechanism of membrane proteins regulated by physical stimuli

    • Principal Investigator
      Nureki Osamu
    • Project Period (FY)
      2016 – 2020
    • Research Category
      Grant-in-Aid for Specially Promoted Research
    • Review Section
      Biological Sciences
    • Research Institution
      The University of Tokyo

All 2023 2022 2021 2020 2019 2018 2017 2016 Other

All Journal Article Presentation Book Other

  • [Book] 月刊「細胞」2021年 5月号 Gタンパク質共役型受容体(GPCR)の新展開2021

    • Author(s)
      松井俊貴, 小柳淳暉, 加藤英明
    • Total Pages
      4
    • Publisher
      北隆館
    • Data Source
      KAKENHI-PROJECT-19H03163
  • [Journal Article] Activation of the urotensin-II receptor by remdesivir induces cardiomyocyte dysfunction2023

    • Author(s)
      Ogawa Akiko、Ohira Seiya、Kato Yuri、Ikuta Tatsuya、Yanagida Shota、Mi Xinya、Ishii Yukina、Kanda Yasunari、Nishida Motohiro、Inoue Asuka、Wei Fan-Yan
    • Journal Title

      Communications Biology

      Volume: 6 Issue: 1 Pages: 1-11

    • DOI

      10.1038/s42003-023-04888-x

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-23K18088, KAKENHI-PROJECT-22K19395, KAKENHI-PUBLICLY-22H04628, KAKENHI-PLANNED-21H05269, KAKENHI-PLANNED-21H05113, KAKENHI-PROJECT-21H04791, KAKENHI-PROJECT-23K24035, KAKENHI-PROJECT-23K24075
  • [Journal Article] Endogenous ligand recognition and structural transition of a human PTH receptor2022

    • Author(s)
      Kobayashi Kazuhiro、Kawakami Kouki、Kusakizako Tsukasa、Miyauchi Hirotake、Tomita Atsuhiro、Kobayashi Kan、Shihoya Wataru、Yamashita Keitaro、Nishizawa Tomohiro、Kato Hideaki E.、Inoue Asuka、Nureki Osamu
    • Journal Title

      Molecular Cell

      Volume: 82 Issue: 18 Pages: 3468-3483

    • DOI

      10.1016/j.molcel.2022.07.003

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-22K15072, KAKENHI-PLANNED-21H05113, KAKENHI-PROJECT-21H04791, KAKENHI-PROJECT-20J21820, KAKENHI-PROJECT-20K15754, KAKENHI-PROJECT-21H05037, KAKENHI-PLANNED-19H05777
  • [Journal Article] Structural insights into the G protein selectivity revealed by the human EP3-Gi signaling complex2022

    • Author(s)
      Ryoji Suno, Yukihiko Sugita, Kazushi Morimoto, Hiroko Takazaki, Hirokazu Tsujimoto, Mika Hirose, Chiyo Suno-Ikeda, Norimichi Nomura, Tomoya Hino, Asuka Inoue, Kenji Iwasaki, Takayuki Kato, So Iwata, Takuya Kobayashi
    • Journal Title

      Cell Rep.

      Volume: 40(11) Issue: 11 Pages: 111323-111323

    • DOI

      10.1016/j.celrep.2022.111323

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-21K19360, KAKENHI-PLANNED-21H05112, KAKENHI-PLANNED-21H05113, KAKENHI-PROJECT-19H00923, KAKENHI-PROJECT-21H04791, KAKENHI-PROJECT-19H03428, KAKENHI-PUBLICLY-22H04753, KAKENHI-PLANNED-19H05777, KAKENHI-PROJECT-20H03434
  • [Journal Article] Cryo-EM structure of the β3-adrenergic receptor reveals the molecular basis of subtype selectivity.2021

    • Author(s)
      Nagiri, C., Kobayashi, K., Tomita, A., Kato, M., Kobayashi, K., Yamashita, K., Nishizawa, T., Inoue, A., Shihoya, W. and Nureki, O.
    • Journal Title

      Mol. Cell

      Volume: 81 Issue: 15 Pages: 3205-3215

    • DOI

      10.1016/j.molcel.2021.06.024

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-16H06294, KAKENHI-PUBLICLY-20H05437, KAKENHI-PROJECT-20J13299, KAKENHI-PROJECT-20K15728, KAKENHI-PROJECT-21H05037
  • [Journal Article] Structure of the neurotensin receptor 1 in complex with β-arrestin 12020

    • Author(s)
      Huang Weijiao、Masureel Matthieu、Qu Qianhui、Janetzko John、Inoue Asuka、Kato Hideaki E.、Robertson Michael J.、Nguyen Khanh C.、Glenn Jeffrey S.、Skiniotis Georgios、Kobilka Brian K.
    • Journal Title

      Nature

      Volume: 579 Issue: 7798 Pages: 303-308

    • DOI

      10.1038/s41586-020-1953-1

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17K08264, KAKENHI-PROJECT-19H03163
  • [Journal Article] Cryo-EM structure of the volume-regulated anion channel LRRC8D isoform identifies features important for substrate permeation2020

    • Author(s)
      Nakamura Ryoki、Numata Tomohiro、Kasuya Go、Yokoyama Takeshi、Nishizawa Tomohiro、Kusakizako Tsukasa、Kato Takafumi、Hagino Tatsuya、Dohmae Naoshi、Inoue Masato、Watanabe Kengo、Ichijo Hidenori、Kikkawa Masahide、Shirouzu Mikako、Jentsch Thomas J.、Ishitani Ryuichiro、Okada Yasunobu、Nureki Osamu
    • Journal Title

      Communications Biology

      Volume: 3 Issue: 1 Pages: 240-240

    • DOI

      10.1038/s42003-020-0951-z

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17H03640, KAKENHI-PROJECT-20K15754, KAKENHI-PLANNED-16H06574, KAKENHI-PROJECT-18H03995, KAKENHI-PROJECT-18K06864, KAKENHI-PROJECT-19K23833, KAKENHI-PROJECT-16H06294
  • [Journal Article] Conformational transitions of a neurotensin receptor?1?Gi1?complex2019

    • Author(s)
      Kato Hideaki E.、Zhang Yan、Hu Hongli、Suomivuori Carl-Mikael、Kadji Francois Marie Ngako、Aoki Junken、Krishna Kumar Kaavya、Fonseca Rasmus、Hilger Daniel、Huang Weijiao、Latorraca Naomi R.、Inoue Asuka、Dror Ron O.、Kobilka Brian K.、Skiniotis Georgios
    • Journal Title

      Nature

      Volume: 572 Issue: 7767 Pages: 80-85

    • DOI

      10.1038/s41586-019-1337-6

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-19H03163, KAKENHI-PROJECT-17K08264
  • [Journal Article] Crystal structure of the Agrobacterium tumefaciens type VI effector-immunity complex.2018

    • Author(s)
      Fukuhara S, Nakane T, Yamashita K, Ishii R, Ishitani R, Nureki O
    • Journal Title

      Acta Crystallogr. F Struct. Biol. Commun.

      Volume: 74 Issue: 3 Pages: 810-816

    • DOI

      10.1038/s41477-019-0367-2

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-17H03640, KAKENHI-PROJECT-17J06203, KAKENHI-PROJECT-16H06294
  • [Journal Article] Structural insights into ligand recognition by the lysophosphatidic acid receptor LPA62017

    • Author(s)
      Taniguchi Reiya、Inoue Asuka、Sayama Misa、Uwamizu Akiharu、Yamashita Keitaro、Hirata Kunio、Yoshida Masahito、Tanaka Yoshiki、Kato Hideaki E.、Nakada-Nakura Yoshiko、Otani Yuko、Nishizawa Tomohiro、Doi Takayuki、Ohwada Tomohiko、Ishitani Ryuichiro、Aoki Junken、Nureki Osamu
    • Journal Title

      Nature

      Volume: 548 Issue: 7667 Pages: 356-360

    • DOI

      10.1038/nature23448

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-16K08157, KAKENHI-PUBLICLY-16H00822, KAKENHI-PROJECT-17H03640, KAKENHI-PROJECT-16J07583, KAKENHI-PROJECT-16J08059, KAKENHI-PROJECT-16H06294, KAKENHI-PROJECT-17H05000
  • [Journal Article] "Role of Asn112 in a light-driven sodium ion-pumping rhodopsin"2016

    • Author(s)
      R. Abe-Yoshizumi, K. Inoue, H. E. Kato, O. Nureki, H. Kandori*
    • Journal Title

      Biochemistry

      Volume: 55 Issue: 41 Pages: 5790-5797

    • DOI

      10.1021/acs.biochem.6b00741

    • Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PLANNED-25104009, KAKENHI-PROJECT-15H02391, KAKENHI-PROJECT-14J40214, KAKENHI-PROJECT-26708001, KAKENHI-PROJECT-26620005, KAKENHI-PROJECT-16H06294
  • [Journal Article] Crystal structure of the plant receptor-like kinase TDR in complex with the TDIF peptide.2016

    • Author(s)
      Morita, J., Kato, K., Nakane, T., Kondo, Y., Fukuda, H., Nishimasu, H., *Ishitani, R. and *Nureki, O.
    • Journal Title

      Nat. Commun.

      Volume: 7 Issue: 1 Pages: 12383-12383

    • DOI

      10.1038/ncomms12383

    • Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PUBLICLY-15H01226, KAKENHI-PLANNED-15H05958, KAKENHI-PROJECT-25291011, KAKENHI-PROJECT-16H06294, KAKENHI-PROJECT-16H06377
  • [Journal Article] Crystal structures of the TRIC trimeric intracellular cation channel orthologues.2016

    • Author(s)
      Kasuya G, Hiraizumi M, Maturana AD, Kumazaki K, Fujiwara Y, Liu K, Nakada-Nakura Y, Iwata S, Tsukada K, Komori T, Uemura S, Goto Y, Nakane T, Takemoto M, Kato HE, Yamashita K, Wada M, Ito K, Ishitani R, Hattori M, Nureki O.
    • Journal Title

      Cell Res.

      Volume: 26 Issue: 12 Pages: 1288-1301

    • DOI

      10.1038/cr.2016.140

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PUBLICLY-16H01389, KAKENHI-PROJECT-15J08129, KAKENHI-PROJECT-25291011, KAKENHI-PROJECT-26291030, KAKENHI-PROJECT-16K15180, KAKENHI-PROJECT-16H06294
  • [Journal Article] Structural and functional insights into IZUMO1 recognition by JUNO in mammalian fertilization.2016

    • Author(s)
      Kato K, Satouh Y, Nishimasu H, Kurabayashi A, Morita J, Fujihara Y, Oji A, Ishitani R, Ikawa M, Nureki O.
    • Journal Title

      Nature Communications

      Volume: 7 Issue: 1 Pages: 12198-12198

    • DOI

      10.1038/ncomms12198

    • NAID

      120006957420

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15H05573, KAKENHI-PROJECT-15J04519, KAKENHI-PROJECT-15J08403, KAKENHI-PROJECT-25291011, KAKENHI-PROJECT-16H06276, KAKENHI-ORGANIZER-25112001, KAKENHI-PROJECT-16H06294
  • [Presentation] CryoEM analysis of the GPCR neurotensin receptor 1 signaling complexes2020

    • Author(s)
      加藤英明
    • Organizer
      東京大学 医学部リサーチカンファ
    • Invited
    • Data Source
      KAKENHI-PROJECT-19H03163
  • [Presentation] CryoEM analysis of the GPCR neurotensin receptor 1 signaling complexes2020

    • Author(s)
      加藤英明
    • Organizer
      第93回 日本生化学会大会
    • Invited
    • Data Source
      KAKENHI-PROJECT-19H03163
  • [Presentation] Structural basis for the recognition of salient signals by GPCRs2020

    • Author(s)
      Hideaki Kato
    • Organizer
      第43回 日本神経科学大会
    • Invited
    • Data Source
      KAKENHI-PROJECT-19H03163
  • [Presentation] CryoEM analysis of the GPCR neurotensin receptor 1-G protein complex for the future engineering of biased allosteric modulator2020

    • Author(s)
      加藤英明
    • Organizer
      第418回 CBI学会講演会
    • Invited
    • Data Source
      KAKENHI-PROJECT-19H03163
  • [Presentation] CryoEM analysis of the GPCR neurotensin receptor 1-G protein complex2019

    • Author(s)
      Hideaki Kato
    • Organizer
      The Joint Symposium on Fusion of Biomedical and Physical/ Informational Sciences in Neurobiology
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-19H03163
  • [Presentation] Structural and conformational transition in NTSR1-Gi1 protein complex2019

    • Author(s)
      加藤英明
    • Organizer
      名古屋工業大学セミナー
    • Invited
    • Data Source
      KAKENHI-PROJECT-19H03163
  • [Presentation] Structural and conformational transition in NTSR1-Gi1 protein complex2019

    • Author(s)
      加藤英明
    • Organizer
      第92回 日本生化学会大会
    • Invited
    • Data Source
      KAKENHI-PROJECT-19H03163
  • [Presentation] Structural and conformational transition in NTSR1-Gi1 protein complex2019

    • Author(s)
      加藤英明
    • Organizer
      第57回 日本生物物理学会年会
    • Invited
    • Data Source
      KAKENHI-PROJECT-19H03163
  • [Presentation] CryoEM analysis of the GPCR neurotensin receptor 1-G protein complex for the future engineering of biased allosteric modulator2019

    • Author(s)
      Hideaki Kato
    • Organizer
      AHeDD2019/IPAB2019 Joint Symposium
    • Invited
    • Data Source
      KAKENHI-PROJECT-19H03163
  • [Presentation] Structural and conformational transition in NTSR1-Gi1 protein complex2019

    • Author(s)
      加藤英明
    • Organizer
      東京大学 第1292回生物科学セミナー
    • Invited
    • Data Source
      KAKENHI-PROJECT-19H03163
  • [Presentation] Structural and conformational transition in NTSR1-Gi1 protein complex2019

    • Author(s)
      加藤英明
    • Organizer
      金沢大学 NanoLSIセミナー
    • Invited
    • Data Source
      KAKENHI-PROJECT-19H03163
  • []

  • 1.  Nureki Osamu (10272460)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 1 results
  • 2.  Okuyama Teruhiro (80625955)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 3.  Yoshizawa Susumu (00553108)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 4.  伊藤 耕一 (10262073)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 5.  MATURANA ANDRES (10452004)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 6.  石谷 隆一郎 (90361568)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 2 results
  • 7.  井上 圭一 (90467001)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 1 results
  • 8.  小林 直也 (60781945)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 9.  竹内 春樹 (70548859)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 10.  三浦 恭子 (80583062)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 11.  井上 飛鳥 (50525813)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 1 results
  • 12.  OTANI Yuko
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 13.  FUJIWARA Yuichiro
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 14.  FUJIHARA Yoshitaka
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 15.  草木迫 司
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 16.  神取 秀樹
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 17.  近藤 侑貴
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 18.  小川 亜希子
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 19.  小林 拓也
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 20.  寿野 良二
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 21.  井上 明俊
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results

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