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Nio Kouki  丹尾 幸樹

ORCIDConnect your ORCID iD *help
Researcher Number 80807397
Other IDs
Affiliation (Current) 2025: 金沢大学, 附属病院, 特任准教授
Affiliation (based on the past Project Information) *help 2019 – 2023: 金沢大学, 附属病院, 助教
2018: 金沢大学, 医学系, 特任助教
Review Section/Research Field
Principal Investigator
Basic Section 53010:Gastroenterology-related
Except Principal Investigator
Basic Section 53010:Gastroenterology-related
Keywords
Principal Investigator
癌幹細胞 / 肝細胞癌 / CXCR2 / 腫瘍微小環境 / 免疫チェックポイント阻害剤 / がん免疫 / シンジェニックマウスモデル / iPS細胞 / PDXマウスモデル / ヒト化マウス … More / がん免疫療法 / 肝胆膵がん / CD105 / 血管新生 / バイオマーカー / BMP受容体阻害剤 / ID1 / BMP9 / がん幹細胞 … More
Except Principal Investigator
循環癌間質細胞 / バイオマーカー / 癌間質細胞 / 癌幹細胞 / 肝癌 Less
  • Research Projects

    (4 results)
  • Research Products

    (10 results)
  • Co-Researchers

    (2 People)
  •  肝癌幹細胞とCXCR2陽性細胞の細胞間相互作用の解析と新規治療法開発Principal Investigator

    • Principal Investigator
      丹尾 幸樹
    • Project Period (FY)
      2023 – 2025
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 53010:Gastroenterology-related
    • Research Institution
      Kanazawa University
  •  肝がんにおける循環癌間質細胞の特性と臨床的意義の探索

    • Principal Investigator
      山下 竜也
    • Project Period (FY)
      2022 – 2024
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 53010:Gastroenterology-related
    • Research Institution
      Kanazawa University
  •  Development of innovative humanized mouse models for immuno-oncology research of hepatobiliary and pancreatic cancerPrincipal Investigator

    • Principal Investigator
      Nio Kouki
    • Project Period (FY)
      2020 – 2023
    • Research Category
      Grant-in-Aid for Early-Career Scientists
    • Review Section
      Basic Section 53010:Gastroenterology-related
    • Research Institution
      Kanazawa University
  •  Development of novel therapeutic strategies targeting BMP9 that contributes to the acquisition of malignant properties in hepatocellular carcinomaPrincipal Investigator

    • Principal Investigator
      Nio Kouki
    • Project Period (FY)
      2018 – 2020
    • Research Category
      Grant-in-Aid for Early-Career Scientists
    • Review Section
      Basic Section 53010:Gastroenterology-related
    • Research Institution
      Kanazawa University

All 2023 2021 2020 2019 2018

All Journal Article Presentation

  • [Journal Article] BMP9‐ID1 signaling promotes EpCAM‐positive cancer stem cell properties in hepatocellular carcinoma2021

    • Author(s)
      Chen Han、Nio Kouki、Yamashita Taro、Okada Hikari、Li Ru、Suda Tsuyoshi、Li Yingyi、Doan Phuong Thi Bich、Seki Akihiro et.al
    • Journal Title

      Molecular Oncology

      Volume: not available Issue: 8 Pages: 2203-2218

    • DOI

      10.1002/1878-0261.12963

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-20K17017, KAKENHI-PROJECT-18K15807, KAKENHI-PROJECT-19K23983, KAKENHI-PROJECT-18K07966, KAKENHI-PROJECT-21H04823, KAKENHI-PROJECT-20K16984
  • [Presentation] Efficacy of VEGFR2-targeted therapy after atezolizumab and bevacizumab combination therapy in hepatocellular carcinoma2023

    • Author(s)
      Nio K, Sugiyama G, Okada H, Yamashita T
    • Organizer
      AASLD 2023
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-20K17044
  • [Presentation] 肝癌幹細胞の活性化に寄与するID1を標的とした治療法の検討2021

    • Author(s)
      丹尾 幸樹、山下 太郎、金子 周一
    • Organizer
      第107回日本消化器病学会総会
    • Data Source
      KAKENHI-PROJECT-18K15807
  • [Presentation] Targeting BMP9-ID1 signaling suppresses cancer stem cell features in hepatocellular carcinoma.2020

    • Author(s)
      Han Chen, Kouki Nio, Taro Yamashita, Hikari Okada, Masao Honda, Shuichi Kaneko
    • Organizer
      58th JSCO
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18K15807
  • [Presentation] 幹細胞性肝細胞癌に対するBMP9シグナル阻害剤の治療効果検討2020

    • Author(s)
      丹尾 幸樹、山下 太郎、金子 周一
    • Organizer
      第56回日本肝臓学会総会
    • Data Source
      KAKENHI-PROJECT-18K15807
  • [Presentation] BMP9 promotes EpCAM-positive cancer stem cell properties in hepatocellular carcinoma via ID1 activation.2020

    • Author(s)
      Kouki Nio, Taro Yamashita, Han Chen, Hikari Okada, Masao Honda, Shuichi Kaneko
    • Organizer
      AASLD 2020
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18K15807
  • [Presentation] 肝細胞癌悪性形質に関わるBMP9分子シグナルが制御する癌幹細胞維持機構の検討2019

    • Author(s)
      丹尾 幸樹、山下 太郎、本多 政夫、金子 周一
    • Organizer
      第55回日本肝臓学会総会
    • Data Source
      KAKENHI-PROJECT-18K15807
  • [Presentation] 肝細胞癌悪性形質に関わるBMP9分子シグナルが制御する癌幹細胞維持機構の検討2019

    • Author(s)
      丹尾 幸樹、山下 太郎、本多 政夫,金子 周一
    • Organizer
      第55回日本肝臓学会総会
    • Data Source
      KAKENHI-PROJECT-18K15807
  • [Presentation] Clinical and biological significance of BMP9 in the malignant nature of hepatocellular carcinoma2019

    • Author(s)
      Kouki Nio, Taro Yamashita, Shuichi Kaneko
    • Organizer
      JDDW2019
    • Data Source
      KAKENHI-PROJECT-18K15807
  • [Presentation] 肝細胞癌におけるBMP9発現の臨床的意義と幹細胞性維持への影響2018

    • Author(s)
      丹尾 幸樹,陳 晗,山下 太郎,金子 周一
    • Organizer
      第54回日本肝癌研究会
    • Data Source
      KAKENHI-PROJECT-18K15807
  • 1.  山下 竜也 (30334783)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 2.  関 晃裕
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results

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