Sakurai Masayuki 櫻井雅之

Researcher Number	80809236
Other IDs	https://orcid.org/0000-0002-6920-1746
Affiliation (Current)	2025: 東京理科大学, 研究推進機構生命医科学研究所, 准教授
Affiliation (based on the past Project Information) *help	2021 – 2024: 東京理科大学, 研究推進機構生命医科学研究所, 准教授 2018 – 2021: 東京理科大学, 研究推進機構生命医科学研究所, 講師
Review Section/Research Field	Principal Investigator Basic Section 43010:Molecular biology-related / 0701:Biology at molecular to cellular levels, and related fields Except Principal Investigator Medium-sized Section 62:Applied informatics and related fields
Keywords	Principal Investigator R-loop / RNA編集 / ADAR / アデノシン脱アミノ化 / ゲノム編集 / エピトランスクリプトーム / イノシン / ノヴァエピヌクレオーム / イノシン化部位標識単離技術ICLAMP / ゲノム動態制御 … More / アデノシン脱アミノ化酵素ADAR / A-to-I DNA編集 / A-to-I RNA編集 / DNA編集 / 塩基脱アミノ化 / 核酸創薬 / 核酸修飾 / 塩基修飾 / RNA editing / DNA 編集 / A-to-I エディティング … More Except Principal Investigator 転写 / RNA分解 / ノンコーディングRNA / RNA Less

RNAリインカネーション
- Principal Investigator
  
  浜田道昭
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Challenging Research (Pioneering)
- Review Section
  
  Medium-sized Section 62:Applied informatics and related fields
- Research Institution
  Waseda University
Genomic DNA deamination editing mechanism regulated by RNA in humanPrincipal Investigator
- Principal Investigator
  
  櫻井雅之
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 43010:Molecular biology-related
- Research Institution
  Tokyo University of Science
Molecular mechanisms of mammalian endogenous RNA-dependent DNA base modification and disease pathogenesis due to dysregulationPrincipal Investigator
- Principal Investigator
  
  Sakurai Masayuki
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 43010:Molecular biology-related
- Research Institution
  Tokyo University of Science
ゲノム&RNA編集酵素ADAR1が司るR-loop制御によるゲノム安定性維持機構Principal Investigator
- Principal Investigator
  
  櫻井雅之
- Project Period (FY)
  2018 – 2019
- Research Category
  
  Grant-in-Aid for Research Activity Start-up
- Review Section
  
  0701:Biology at molecular to cellular levels, and related fields
- Research Institution
  Tokyo University of Science

All 2024 2023 2019 2018

All Journal Article Presentation Book Patent

[Book] 実験医学2018
- Author(s)
  4.櫻井雅之, 長谷川拓巳, 中山宏紀
- Total Pages
  5
- Publisher
  羊土社
- ISBN
  9784758125147
- Data Source
  KAKENHI-PROJECT-18H06054
[Journal Article] ICLAMP: a novel technique to explore adenosine deamination via inosine chemical labeling and affinity molecular purification2024
- Author(s)
  Yang Yuxi、Nakayama Koki、Okada Shunpei、Sato Kazuki、Wada Takeshi、Sakaguchi Yuriko、Murayama Ayaka、Suzuki Tsutomu、Sakurai Masayuki
- Journal Title
  
  FEBS Letters
  
  Volume: in press Issue: 9 Pages: 1080-1093
- DOI
  10.1002/1873-3468.14854
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18H05272, KAKENHI-PROJECT-23K23812
[Journal Article] Discovering RNA editing by chemical methods2019
- Author(s)
  Sakurai, M.*(Corresponding Author), Okada, S., Ueda, H.
- Journal Title
  
  Methods Mol. Biol.
  
  Volume: in press
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18H06054
[Patent] イノシン塩基の標識方法、イノシン塩基の検出方法、核酸の配列決定方法、イノシン塩基を含む核酸の濃縮方法、イノシン塩基標識剤、及びキット2023
- Inventor(s)
  櫻井雅之, 楊雨溪, 中山宏紀, 岡田俊平, 和田猛, 佐藤一樹
- Industrial Property Rights Holder
  学校法人東京理科大学
- Industrial Property Rights Type
  特許
- Industrial Property Number
  2023-175606
- Filing Date
  2023
- Acquisition Date
  2023
- Data Source
  KAKENHI-PROJECT-23K23812
[Presentation] The short isoform of ADAR1 contributes to cell maintenance in DNA repair and mitosis regulation.2023
- Author(s)
  Kubota, M., Nishikura, K., Shiromoto, Y., Sakurai, M.
- Organizer
  第24回日本RNA学会年会
- Data Source
  KAKENHI-PROJECT-23K23812
[Presentation] アデノシン脱アミノ化によるRNA:DNA鎖を介したDNA動態制御2023
- Author(s)
  櫻井雅之
- Organizer
  第9回がんと代謝研究会
- Data Source
  KAKENHI-PROJECT-23K23812
[Presentation] Development of a new technique to isolate inosine-containing molecules from intracellular nucleic acid.2023
- Author(s)
  Yang, Y., Nakayama, K., Okada, S., Sato, K. Wada, T., Sakurai, M.
- Organizer
  第24回日本RNA学会年会
- Data Source
  KAKENHI-PROJECT-23K23812
[Presentation] アデノシン脱アミノ化編集酵素によるDNA編集とその動態制御2023
- Author(s)
  櫻井雅之
- Organizer
  日本核酸医薬学会「生物セッション第6回サテライトシンポジウム」　―RNA が制御する多様な生命機能―
- Data Source
  KAKENHI-PROJECT-23K23812
[Presentation] Adenosine-to-inosine base editing by ADAR; new features for DNA regulation.2023
- Author(s)
  Sakurai, M., Yang, Y., Kubota, M., Ichihashi, E., Nishikura, K., Shiromoto, Y., Minakuchi, M.
- Organizer
  第24回日本RNA学会年会
- Data Source
  KAKENHI-PROJECT-23K23812
[Presentation] Regulation of Genome Stability by ADAR RNA Editing Enzymes2019
- Author(s)
  Nishikura, K, Sakurai, M., Shiromoto, Y., Ariyoshi, K., Kossenkov, A.V., Wickramasinghe, J., Showe, L.C.
- Organizer
  2019 Gordon Research Conference, RNA editing
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18H06054
[Presentation] ADAR1 controls apoptosis of stressed cells by inhibitin Staufen-mediated mRNA decay.2018
- Author(s)
  Sakurai, M., Shiromoto, Y., Ota, H., Song, C., Kossenkov, A.V., Wickramasinghe, J., Showe, L.C., Skordalakes, E., Tao, H.Y., Speicher, D.W., and Nishikura, K.
- Organizer
  The 20th RNA meeting. 第20回日本RNA学会年会
- Data Source
  KAKENHI-PROJECT-18H06054
[Presentation] RNA adenosine deaminase regulates embryogenesis and cancer metastasis.2018
- Author(s)
  Sakurai, M., Gumireddy, K., Li, A., Kossenkov, A.V., Yan, J., Li, Y., Xu, H., Wang, J., Zhang, PJ., Zhang, L., Showe, L., Nishikura, K., and Huang, Q.
- Organizer
  The 2nd International Innovation Dialogue on Genome Engineering Animal Models and Biomedical Research Symposium
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18H06054

1. 浜田道昭 (00596538)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
2. 秋光信佳 (40294962)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
3. 鈴木勉

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Sakurai Masayuki 櫻井 雅之

Research Projects

Research Products

Co-Researchers

RNAリインカネーション

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Genomic DNA deamination editing mechanism regulated by RNA in humanPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Molecular mechanisms of mammalian endogenous RNA-dependent DNA base modification and disease pathogenesis due to dysregulationPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

ゲノム&RNA編集酵素ADAR1が司るR-loop制御によるゲノム安定性維持機構Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

[Book] 実験医学2018

Author(s)

Total Pages

Publisher

ISBN

Data Source

[Journal Article] ICLAMP: a novel technique to explore adenosine deamination via inosine chemical labeling and affinity molecular purification2024

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Discovering RNA editing by chemical methods2019

Author(s)

Journal Title

Data Source

[Patent] イノシン塩基の標識方法、イノシン塩基の検出方法、核酸の配列決定方法、イノシン塩基を含む核酸の濃縮方法、イノシン塩基標識剤、及びキット2023

Inventor(s)

Industrial Property Rights Holder

Industrial Property Rights Type

Industrial Property Number

Filing Date

Acquisition Date

Data Source

[Presentation] The short isoform of ADAR1 contributes to cell maintenance in DNA repair and mitosis regulation.2023

Author(s)

Organizer

Data Source

[Presentation] アデノシン脱アミノ化によるRNA:DNA鎖を介したDNA動態制御2023

Author(s)

Organizer

Data Source

[Presentation] Development of a new technique to isolate inosine-containing molecules from intracellular nucleic acid.2023

Author(s)

Organizer

Data Source

[Presentation] アデノシン脱アミノ化編集酵素によるDNA編集とその動態制御2023

Author(s)

Organizer

Data Source

[Presentation] Adenosine-to-inosine base editing by ADAR; new features for DNA regulation.2023

Author(s)

Organizer

Data Source

[Presentation] Regulation of Genome Stability by ADAR RNA Editing Enzymes2019

Author(s)

Organizer

Data Source

[Presentation] ADAR1 controls apoptosis of stressed cells by inhibitin Staufen-mediated mRNA decay.2018

Author(s)

Organizer

Data Source

[Presentation] RNA adenosine deaminase regulates embryogenesis and cancer metastasis.2018

Sakurai Masayuki 櫻井雅之