Endo Eisei 遠藤英成

Researcher Number	80836271
Affiliation (Current)	2025: 福島県立医科大学, 医学部, 博士研究員
Affiliation (based on the past Project Information) *help	2020 – 2023: 福島県立医科大学, 医学部, 博士研究員 2019: 福島県立医科大学, 医学部, 病院助手
Review Section/Research Field	Principal Investigator Basic Section 55020:Digestive surgery-related Except Principal Investigator Basic Section 55020:Digestive surgery-related
Keywords	Principal Investigator 免疫療法 / dMMR / 免疫チェックポイント / TGF-b / MSI-H / 腫瘍微小環境 / マクロファージ / 大腸癌 Except Principal Investigator トランスクリプトミクス / 間質 … More / 微小環境 / 癌間質 / 腫瘍微小環境 / 大腸癌 Less

Immunosuppressive cells in the tumor microenvironment in colorectal cancerPrincipal Investigator
- Principal Investigator
  
  Endo Eisei
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 55020:Digestive surgery-related
- Research Institution
  Fukushima Medical University
The tumor microenvironment in colorectal cancer
- Principal Investigator
  
  Ohki Shinji
- Project Period (FY)
  2019 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 55020:Digestive surgery-related
- Research Institution
  Fukushima Medical University

All 2023 2022 2021 2020 2019

All Journal Article Presentation

[Journal Article] TIM-3 Expression and M2 Polarization of Macrophages in the TGFβ-Activated Tumor Microenvironment in Colorectal Cancer2023
- Author(s)
  Katagata Masanori、Okayama Hirokazu、Nakajima Shotaro、Saito Katsuharu、Sato Takahiro、Sakuma Mei、Fukai Satoshi、Endo Eisei、Sakamoto Wataru、Saito Motonobu、Saze Zenichiro、Momma Tomoyuki、Mimura Kosaku、Kono Koji
- Journal Title
  
  Cancers
  
  Volume: 15 Issue: 20 Pages: 4943-4943
- DOI
  10.3390/cancers15204943
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K08675, KAKENHI-PROJECT-22K08780, KAKENHI-PROJECT-20K09083, KAKENHI-PROJECT-21K16454, KAKENHI-PROJECT-23K24410
[Journal Article] The Impact of Tumor Cell-Intrinsic Expression of Cyclic GMP-AMP Synthase (cGAS)-Stimulator of Interferon Genes (STING) on the Infiltration of CD8+ T Cells and Clinical Outcomes in Mismatch Repair Proficient/Microsatellite Stable Colorectal Cancer2023
- Author(s)
  Nakajima Shotaro、Kaneta Akinao、Okayama Hirokazu、Saito Katsuharu、Kikuchi Tomohiro、Endo Eisei、Matsumoto Takuro、Fukai Satoshi、Sakuma Mei、Sato Takahiro、Mimura Kosaku、Saito Motonobu、Saze Zenichiro、Sakamoto Wataru、Onozawa Hisashi、Momma Tomoyuki、Kono Koji
- Journal Title
  
  Cancers
  
  Volume: 15 Issue: 10 Pages: 2826-2826
- DOI
  10.3390/cancers15102826
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K08675, KAKENHI-PROJECT-20K09083, KAKENHI-PROJECT-21K16454, KAKENHI-PROJECT-23K24410
[Journal Article] Role of the cGAS-STING pathway in regulating the tumor-immune microenvironment in dMMR/MSI colorectal cancer2022
- Author(s)
  Kaneta Akinao、Nakajima Shotaro、Okayama Hirokazu、Matsumoto Takuro、Saito Katsuharu、Kikuchi Tomohiro、Endo Eisei、Ito Misato、Mimura Kosaku、Kanke Yasuyuki、Saito Motonobu、Saze Zenichiro、Fujita Shotaro、Sakamoto Wataru、Onozawa Hisashi、Momma Tomoyuki、Ohki Shinji、Kono Koji
- Journal Title
  
  Cancer Immunology, Immunotherapy
  
  Volume: ‐ Issue: 11 Pages: 2765-2776
- DOI
  10.1007/s00262-022-03200-w
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K09180, KAKENHI-PROJECT-21K08802, KAKENHI-PROJECT-20K09083, KAKENHI-PROJECT-21K08675, KAKENHI-PROJECT-21K08758, KAKENHI-PROJECT-22K08779, KAKENHI-PROJECT-19K09128, KAKENHI-PROJECT-23K24410
[Journal Article] Therapeutic potential of anti-VEGF receptor 2 therapy targeting for M2-tumor-associated macrophages in colorectal cancer2021
- Author(s)
  Min Aung Kyi Thar、Mimura Kosaku、Nakajima Shotaro、Okayama Hirokazu、Saito Katsuharu、Sakamoto Wataru、Fujita Shotaro、Endo Hisahito、Saito Motonobu、Saze Zenichiro、Momma Tomoyuki、Ohki Shinji、Kono Koji
- Journal Title
  
  Cancer Immunology, Immunotherapy
  
  Volume: 70 Issue: 2 Pages: 289-298
- DOI
  10.1007/s00262-020-02676-8
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K09180
[Journal Article] A TGFβ-Dependent Stromal Subset Underlies Immune Checkpoint Inhibitor Efficacy in DNA Mismatch Repair?Deficient/Microsatellite Instability-High Colorectal Cancer2020
- Author(s)
  Endo Eisei、Okayama Hirokazu、Saito Katsuharu、Nakajima Shotaro、Yamada Leo、Ujiie Daisuke、Kase Koji、Fujita Shotaro、Endo Hisahito、Sakamoto Wataru、Saito Motonobu、Saze Zenichiro、Momma Tomoyuki、Ohki Shinji、Mimura Kosaku、Kono Koji
- Journal Title
  
  Molecular Cancer Research
  
  Volume: 18 Issue: 9 Pages: 1402-1413
- DOI
  10.1158/1541-7786.mcr-20-0308
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K09151, KAKENHI-PROJECT-19K09180, KAKENHI-PROJECT-18K08712
[Journal Article] KRT17 as a prognostic biomarker for stage II colorectal cancer2019
- Author(s)
  Ujiie Daisuke、Okayama Hirokazu、Saito Katsuharu、Ashizawa Mai、Thar Min Aung Kyi、Endo Eisei、Kase Koji、Yamada Leo、Kikuchi Tomohiro、Hanayama Hiroyuki、Fujita Shotaro、Sakamoto Wataru、Endo Hisahito、Saito Motonobu、Mimura Kosaku、Saze Zenichiro、Momma Tomoyuki、Ohki Shinji、Kono Koji
- Journal Title
  
  Carcinogenesis
  
  Volume: 0 Issue: 5 Pages: 0-0
- DOI
  10.1093/carcin/bgz192
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K08652, KAKENHI-PROJECT-18K08712, KAKENHI-PROJECT-17K10597, KAKENHI-PROJECT-19K09151, KAKENHI-PROJECT-19K09180
[Journal Article] A subset of patients with MSS/MSI?low?colorectal cancer showed increased CD8(+) TILs together with up?regulated IFN?γ2019
- Author(s)
  Kikuchi Tomohiro、Mimura Kosaku、Okayama Hirokazu、Nakayama Yuko、Saito Katsuharu、Yamada Leo、Endo Eisei、Sakamoto Wataru、Fujita Shotaro、Endo Hisahito、Saito Motonobu、Momma Tomoyuki、Saze Zenichiro、Ohki Shinji、Kono Koji
- Journal Title
  
  Oncology Letters
  
  Volume: 66 Pages: 10-66
- DOI
  10.3892/ol.2019.10953
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K08652, KAKENHI-PROJECT-18K08712, KAKENHI-PROJECT-19K09128, KAKENHI-PROJECT-19K09151, KAKENHI-PROJECT-19K09180, KAKENHI-PROJECT-17K10597
[Journal Article] Characterization of tumor-infiltrating immune cells in relation to microbiota in colorectal cancers2019
- Author(s)
  Kikuchi Tomohiro、Mimura Kosaku、Ashizawa Mai、Okayama Hirokazu、Endo Eisei、Saito Katsuharu、Sakamoto Wataru、Fujita Shotaro、Endo Hisahito、Saito Motonobu、Momma Tomoyuki、Saze Zenichiro、Ohki Shinji、Shimada Kazunori、Yoshimura Kiyoshi、Tsunoda Takuya、Kono Koji
- Journal Title
  
  Cancer Immunology, Immunotherapy
  
  Volume: 69 Issue: 1 Pages: 23-32
- DOI
  10.1007/s00262-019-02433-6
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K07320, KAKENHI-PROJECT-19K09180, KAKENHI-PROJECT-17K10597
[Journal Article] microRNA-148a-3p regulates immunosuppression in DNA mismatch repair-deficient colorectal cancer by targeting PD-L12019
- Author(s)
  Ashizawa Mai、Okayama Hirokazu、Ishigame Teruhide、Thar Min Aung Kyi、Saito Katsuharu、Ujiie Daisuke、Murakami Yuko、Kikuchi Tomohiro、Nakayama Yuko、Noda Masaru、Tada Takeshi、Endo Hisahito、Fujita Shotaro、Sakamoto Wataru、Saito Motonobu、Saze Zenichiro、Momma Tomoyuki、Ohki Shinji、Mimura Kosaku、Kono Koji
- Journal Title
  
  Molecular Cancer Research
  
  Volume: Epub ahead of print Issue: 6 Pages: 1403-1413
- DOI
  10.1158/1541-7786.mcr-18-0831
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K07146, KAKENHI-PROJECT-16K19946, KAKENHI-PROJECT-17K10643, KAKENHI-PROJECT-18K08652, KAKENHI-PROJECT-18K08712, KAKENHI-PROJECT-19K09151, KAKENHI-PROJECT-19K09180, KAKENHI-PROJECT-16K10511
[Presentation] 癌間質におけるTGF-βと腫瘍浸潤免疫細胞でのTIM3の発現との関連について2023
- Author(s)
  片方雅紀, 岡山洋和, 中嶋正太郎, 遠藤英成, 佐藤孝洋, 齋藤元伸, 佐瀬善一郎, 門馬智之, 三村耕作, 河野浩二
- Organizer
  第78回日本消化器外科学会総会
- Data Source
  KAKENHI-PROJECT-21K16454
[Presentation] 腫瘍細胞内cGAS-STING経路がpMMR/MSS大腸癌のCD8+ T細胞浸潤や予後に及ぼす影響2023
- Author(s)
  中嶋正太郎, 金田晃尚, 岡山洋和, 菊池智宏, 遠藤英成, 松本拓朗, 佐久間芽衣, 三村耕作, 齋藤元伸, 佐瀬善一郎, 坂本渉, 小野澤寿志, 門馬智之, 河野浩二
- Organizer
  第82回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-21K16454
[Presentation] TGFβ活性を有する腫瘍微小環境のTIM-3とM2マクロファージへの影響について2023
- Author(s)
  片方雅紀, 岡山洋和, 中嶋正太郎, 遠藤英成, 齋藤勝治, 佐藤孝洋, 佐久間芽衣, 深井智司, 坂本渉, 齋藤元伸, 佐瀬善一郎, 門馬智之, 三村耕作, 河野浩二
- Organizer
  第61回日本癌治療学会学術集会
- Data Source
  KAKENHI-PROJECT-21K16454
[Presentation] 大腸鋸歯状病変における間質プロファイリングの試み2023
- Author(s)
  岡山洋和, 片方雅紀, 遠藤英成, 佐久間芽衣, 佐藤孝洋, 深井智司, 坂本渉, 佐瀬善一郎, 門馬智之, 河野浩二
- Organizer
  第78回日本消化器外科学会総会
- Data Source
  KAKENHI-PROJECT-21K16454
[Presentation] Molecular subtypes of colorectal cancer2023
- Author(s)
  岡山洋和, 片方雅紀, 佐藤孝洋, 深井智司, 佐久間芽衣, 松本拓朗, 遠藤英成, 氏家大輔, 小野澤寿志, 藤田正太郎, 坂本渉, 齋藤元伸, 佐瀬善一郎, 門馬智之, 中嶋正太郎, 三村耕作, 河野浩二
- Organizer
  第123回日本外科学会定期学術集会
- Data Source
  KAKENHI-PROJECT-21K16454
[Presentation] Targeting the tumor immune microenvironment in colorectal cancer2022
- Author(s)
  岡山洋和, 松本拓朗, 遠藤英成, 金田晃尚, 伊藤美郷, 齋藤元伸, 佐瀬善一郎, 門馬智之, 三村耕作, 河野浩二.
- Organizer
  第77回日本消化器外科学会総会
- Data Source
  KAKENHI-PROJECT-21K16454
[Presentation] dMMR/MSI-H大腸癌におけるTGF-β活性型腫瘍微小環境の同定2020
- Author(s)
  遠藤英成 , 岡山洋和, 加瀬晃志, 山田玲央, 氏家大輔, 藤田正太郎, 坂本渉, 遠藤久仁, 齋藤元伸, 佐瀬善一郎, 門馬智之, 大木進司, 三村耕作, 河野浩二.
- Organizer
  第58回日本癌治療学会学術集会
- Data Source
  KAKENHI-PROJECT-19K09180
[Presentation] dMMR大腸癌におけるTGF-b活性型腫瘍微小環境の同定2020
- Author(s)
  遠藤英成, 岡山洋和, 加瀬晃志, 山田玲央, 氏家大輔, 藤田正太郎, 坂本渉, 遠藤久仁, 齋藤元伸, 佐瀬善一郎, 門馬智之, 大木進司, 三村耕作, 河野浩二.
- Organizer
  第26回日本遺伝性腫瘍学会学術集会
- Data Source
  KAKENHI-PROJECT-19K09180
[Presentation] Stage II 大腸癌の再発予後予測因子としての複合炎症栄養マーカーの有用性に関する検討2020
- Author(s)
  大木進司, 小野澤寿志, 岡山洋和, 坂本渉, 藤田正太郎, 遠藤久仁, 齋藤元伸, 門馬智之, 佐瀬善一郎, 河野浩二.
- Organizer
  第75回日本消化器外科学会総会
- Data Source
  KAKENHI-PROJECT-19K09180
[Presentation] dMMR 大腸癌再発例における癌微小環境の特徴2020
- Author(s)
  遠藤英成, 岡山洋和, 加瀬晃志, 山内直人, 山田玲央, 氏家大輔, 坂本渉, 藤田正太郎, 遠藤久仁, 齋藤元伸, 佐瀬善一郎, 門馬智之, 三村耕作, 大木進司, 河野浩二.
- Organizer
  第120回日本外科学会定期学術集会
- Data Source
  KAKENHI-PROJECT-19K09180
[Presentation] 大腸癌における腫瘍関連マクロファージの分布2019
- Author(s)
  松石彬, 菊池智宏, 三村耕作, 岡山洋和, 藤田正太郎, 遠藤久仁, 坂本渉, 齋藤元伸, 門馬智之, 大木進司, 河野浩二
- Organizer
  第57回日本癌治療学会学術集会
- Data Source
  KAKENHI-PROJECT-19K09180
[Presentation] 大腸癌間質に基づく個別化治療の可能性2019
- Author(s)
  遠藤英成, 岡山洋和, 佐藤孝洋, 菊池智宏, 青砥慶太, 多田武志, 渡辺洋平, 花山寛之, 坂本渉, 藤田正太郎, 遠藤久仁, 齋藤元伸, 権田憲士, 佐瀬善一郎, 門馬智之, 三村耕作, 大木進司, 河野浩二
- Organizer
  第119回日本外科学会定期学術集会
- Data Source
  KAKENHI-PROJECT-19K09180
[Presentation] 大腸癌における腫瘍血管新生の評価2019
- Author(s)
  遠藤英成, 加瀬晃志, 仲野宏, 山田玲央, 氏家大輔, 遠藤久仁, 藤田正太郎, 坂本渉, 齋藤元伸, 佐瀬善一郎, 門馬智之, 三村耕作, 大木進司, 河野浩二
- Organizer
  第57回日本癌治療学会学術集会
- Data Source
  KAKENHI-PROJECT-19K09180
[Presentation] Stage II,III大腸癌に対する複合バイオマーカーを用いた新規予後予測スコアの開発2019
- Author(s)
  大木進司, 千田埈, 岡山和洋, 藤田正太郎, 坂本渉, 遠藤久仁, 齋藤元伸, 門馬智之, 佐瀬善一郎, 河野浩二
- Organizer
  第74回日本消化器外科学会総会
- Data Source
  KAKENHI-PROJECT-19K09180
[Presentation] Multi-omics approaches towards precision medicine in colorectal cancer2019
- Author(s)
  Okayama H, Endo E, Ujiie D, Kikuchi T, Saito M, Saze Z, Momma T, Mimura K, Ohki S, Kono K
- Organizer
  第57回日本癌治療学会学術集会
- Data Source
  KAKENHI-PROJECT-19K09180
[Presentation] 大腸癌におけるMSI status と，PD-L1発現およびCD8 陽性細胞浸潤数の関連2019
- Author(s)
  菊池智宏, 三村耕作, 佐藤孝洋, 岡山洋和, 遠藤久仁, 坂本渉, 藤田正太郎, 齋藤元伸, 門馬智之, 大木進司, 河野浩二
- Organizer
  第119回日本外科学会定期学術集会
- Data Source
  KAKENHI-PROJECT-19K09180

1. Ohki Shinji (20381361)

# of Collaborated Projects: 1 results

# of Collaborated Products: 12 results
2. 岡山洋和 (20583397)

# of Collaborated Projects: 1 results

# of Collaborated Products: 13 results
3. YOSHIMURA Kiyoshi

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
4. 齋藤元伸

# of Collaborated Projects: 0 results

# of Collaborated Products: 4 results
5. 石亀輝英

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Endo Eisei 遠藤 英成

Research Projects

Research Products

Co-Researchers

Immunosuppressive cells in the tumor microenvironment in colorectal cancerPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

The tumor microenvironment in colorectal cancer

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

[Journal Article] TIM-3 Expression and M2 Polarization of Macrophages in the TGFβ-Activated Tumor Microenvironment in Colorectal Cancer2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] The Impact of Tumor Cell-Intrinsic Expression of Cyclic GMP-AMP Synthase (cGAS)-Stimulator of Interferon Genes (STING) on the Infiltration of CD8+ T Cells and Clinical Outcomes in Mismatch Repair Proficient/Microsatellite Stable Colorectal Cancer2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Role of the cGAS-STING pathway in regulating the tumor-immune microenvironment in dMMR/MSI colorectal cancer2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Therapeutic potential of anti-VEGF receptor 2 therapy targeting for M2-tumor-associated macrophages in colorectal cancer2021

Author(s)

Journal Title

DOI

Data Source

[Journal Article] A TGFβ-Dependent Stromal Subset Underlies Immune Checkpoint Inhibitor Efficacy in DNA Mismatch Repair?Deficient/Microsatellite Instability-High Colorectal Cancer2020

Author(s)

Journal Title

DOI

Data Source

[Journal Article] KRT17 as a prognostic biomarker for stage II colorectal cancer2019

Author(s)

Journal Title

DOI

Data Source

[Journal Article] A subset of patients with MSS/MSI?low?colorectal cancer showed increased CD8(+) TILs together with up?regulated IFN?γ2019

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Characterization of tumor-infiltrating immune cells in relation to microbiota in colorectal cancers2019

Author(s)

Journal Title

DOI

Data Source

[Journal Article] microRNA-148a-3p regulates immunosuppression in DNA mismatch repair-deficient colorectal cancer by targeting PD-L12019

Author(s)

Journal Title

DOI

Data Source

[Presentation] 癌間質におけるTGF-βと腫瘍浸潤免疫細胞でのTIM3の発現との関連について2023

Author(s)

Organizer

Data Source

[Presentation] 腫瘍細胞内cGAS-STING経路がpMMR/MSS大腸癌のCD8+ T細胞浸潤や予後に及ぼす影響2023

Author(s)

Organizer

Data Source

[Presentation] TGFβ活性を有する腫瘍微小環境のTIM-3とM2マクロファージへの影響について2023

Author(s)

Organizer

Data Source

[Presentation] 大腸鋸歯状病変における間質プロファイリングの試み2023

Author(s)

Organizer

Data Source

[Presentation] Molecular subtypes of colorectal cancer2023

Author(s)

Organizer

Endo Eisei 遠藤英成