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Yokokawa Takumi  横川 拓海

Researcher Number 80844323
Other IDs
  • ORCIDhttps://orcid.org/0000-0002-3813-4958
Affiliation (Current) 2025: 京都大学, 農学研究科, 助教
Affiliation (based on the past Project Information) *help 2021 – 2025: 京都大学, 農学研究科, 助教
2020: 立命館大学, 食マネジメント学部, 助手
2019: 立命館大学, 総合科学技術研究機構, 研究員
Review Section/Research Field
Principal Investigator
Basic Section 59020:Sports sciences-related / 0909:Sports sciences, physical education, health sciences, and related fields
Except Principal Investigator
Basic Section 59020:Sports sciences-related / Medium-sized Section 59:Sports sciences, physical education, health sciences, and related fields / Basic Section 59040:Nutrition science and health science-related
Keywords
Principal Investigator
運動 / 学習 / 脳 / シナプス / 海馬 / 情動 / 臓器連関 / 脂肪組織 / 不安様行動 / 脂肪細胞 … More / Arcadlin / IGF-I / インスリン様成長因子 / インスリン様成長因子1 / インスリン成長因子1 / 骨格筋 / インスリン様成長因子1 … More
Except Principal Investigator
骨格筋 / 糖化ストレス / 運動 / 臓器連関 / 糖化 / 老化 / 臓器関連 / 個体老化 / 筋再生 / ニューログロビン / マイオカイン / AMPキナーゼ / 脳 / 非酵素的翻訳後修飾 / IMC / イメージング / イメージング・マスサイトメトリー / 食品成分 / 栄養 / シグナル伝達 / グロビン蛋白質 Less
  • Research Projects

    (9 results)
  • Research Products

    (30 results)
  • Co-Researchers

    (12 People)
  •  運動模倣剤開発標的としての脂肪細胞GPCRの応用可能性の検証Principal Investigator

    • Principal Investigator
      横川 拓海
    • Project Period (FY)
      2025 – 2027
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Review Section
      Basic Section 59020:Sports sciences-related
    • Research Institution
      Kyoto University
  •  脳神経保護タンパク質に対する糖化ストレスの影響ならびに運動効果の検証

    • Principal Investigator
      岩中 伸壮
    • Project Period (FY)
      2024 – 2026
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 59020:Sports sciences-related
    • Research Institution
      Kyoto Koka Women's University
  •  骨格筋糖化に着眼した個体老化の誘導機序解明

    • Principal Investigator
      林 達也
    • Project Period (FY)
      2023 – 2025
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Review Section
      Basic Section 59020:Sports sciences-related
    • Research Institution
      Kyoto University
  •  運動による脳の健康増進における脂肪組織の寄与の解明Principal Investigator

    • Principal Investigator
      横川 拓海
    • Project Period (FY)
      2023 – 2025
    • Research Category
      Grant-in-Aid for Early-Career Scientists
    • Review Section
      Basic Section 59020:Sports sciences-related
    • Research Institution
      Kyoto University
  •  非酵素的翻訳後修飾の可視化から骨格筋の老化を「見る」

    • Principal Investigator
      江川 達郎
    • Project Period (FY)
      2022 – 2024
    • Research Category
      Grant-in-Aid for Challenging Research (Pioneering)
    • Review Section
      Medium-sized Section 59:Sports sciences, physical education, health sciences, and related fields
    • Research Institution
      Kyoto University
  •  Role of skeletal muscle AMPK in exercise-induced enhancement of brain functions

    • Principal Investigator
      Hayashi Tatsuya
    • Project Period (FY)
      2022 – 2023
    • Research Category
      Grant-in-Aid for Challenging Research (Exploratory)
    • Review Section
      Medium-sized Section 59:Sports sciences, physical education, health sciences, and related fields
    • Research Institution
      Kyoto University
  •  Role of Arcadlin in exercise-induced enhancement of brain functionsPrincipal Investigator

    • Principal Investigator
      Yokokawa Takumi
    • Project Period (FY)
      2020 – 2022
    • Research Category
      Grant-in-Aid for Early-Career Scientists
    • Review Section
      Basic Section 59020:Sports sciences-related
    • Research Institution
      Kyoto University
      Ritsumeikan University
  •  健康寿命延伸を目指したグロビン蛋白質生合成シグナルの解明

    • Principal Investigator
      岩中 伸壮
    • Project Period (FY)
      2020 – 2024
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 59040:Nutrition science and health science-related
    • Research Institution
      Kyoto Koka Women's University
  •  Role of skeletal muscle-derived IGF-I in exercise-induced enhancement of brain functionsPrincipal Investigator

    • Principal Investigator
      Yokokawa Takumi
    • Project Period (FY)
      2019 – 2022
    • Research Category
      Grant-in-Aid for Research Activity Start-up
    • Review Section
      0909:Sports sciences, physical education, health sciences, and related fields
    • Research Institution
      Kyoto University
      Ritsumeikan University

All 2024 2023 2022 2021 2020 2019

All Journal Article Presentation

  • [Journal Article] Glycative stress inhibits hypertrophy and impairs cell membrane integrity in overloaded mouse skeletal muscle2024

    • Author(s)
      Egawa Tatsuro、Ogawa Takeshi、Yokokawa Takumi、Kido Kohei、Iyama Ryota、Zhao Haiyu、Kurogi Eriko、Goto Katsumasa、Hayashi Tatsuya
    • Journal Title

      Journal of Cachexia, Sarcopenia and Muscle

      Volume: - Issue: 3 Pages: 1-14

    • DOI

      10.1002/jcsm.13444

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-23K16695, KAKENHI-PROJECT-22K19750, KAKENHI-PROJECT-23K21598, KAKENHI-PROJECT-23K27973
  • [Journal Article] Altered expression of synaptic proteins and adhesion molecules in the hippocampus and cortex following the onset of diabetes in nonobese diabetic mice2023

    • Author(s)
      Yokokawa Takumi、Kido Kohei、Sato Koji、Hayashi Tatsuya、Fujita Satoshi
    • Journal Title

      Physiological Reports

      Volume: 11 Issue: 8

    • DOI

      10.14814/phy2.15673

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-22K19750, KAKENHI-PROJECT-20K19498, KAKENHI-PROJECT-19K24330, KAKENHI-PROJECT-21K11466
  • [Journal Article] <scp>CRTC1</scp> deficiency, specifically in melanocortin‐4 receptor‐expressing cells, induces hyperphagia, obesity, and insulin resistance2022

    • Author(s)
      Matsumura Shigenobu、Miyakita Motoki、Miyamori Haruka、Kyo Satomi、Ishikawa Fuka、Sasaki Tsutomu、Jinno Tomoki、Tanaka Jin、Fujita Kotomi、Yokokawa Takumi、Goto Tsuyoshi、Momma Keiko、Takenaka Shigeo、Inoue Kazuo
    • Journal Title

      The FASEB Journal

      Volume: 36 Issue: 12

    • DOI

      10.1096/fj.202200617r

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19H02909, KAKENHI-PROJECT-20K19498, KAKENHI-PROJECT-19K24330
  • [Journal Article] Stimulation of G<sub>s</sub> signaling in MC4R cells by DREADD increases energy expenditure, suppresses food intake, and increases locomotor activity in mice2022

    • Author(s)
      Matsumura Shigenobu、Miyakita Motoki、Miyamori Haruka、Kyo Satomi、Shima Daisuke、Yokokawa Takumi、Ishikawa Fuka、Sasaki Tsutomu、Jinno Tomoki、Tanaka Jin、Goto Tsuyoshi、Momma Keiko、Ishihara Kengo、Berdeaux Rebecca、Inoue Kazuo
    • Journal Title

      American Journal of Physiology-Endocrinology and Metabolism

      Volume: 322 Issue: 5 Pages: E436-E445

    • DOI

      10.1152/ajpendo.00439.2021

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-20K19498, KAKENHI-PROJECT-19K24330, KAKENHI-PROJECT-19H02909
  • [Journal Article] Association of serum brain-derived neurotrophic factor with hepatic enzymes, AST/ALT ratio, and FIB-4 index in middle-aged and older women2022

    • Author(s)
      Yokokawa Takumi、Sasaki Shohei、Sase Kohei、Yoshii Naomi、Yasuda Jun、Hayashi Tatsuya、Fujita Satoshi
    • Journal Title

      PLOS ONE

      Volume: 17 Issue: 8 Pages: e0273056-e0273056

    • DOI

      10.1371/journal.pone.0273056

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-22K19750, KAKENHI-PROJECT-21KK0177, KAKENHI-PROJECT-20K19498, KAKENHI-PROJECT-19K24330, KAKENHI-PROJECT-23K24732
  • [Journal Article] Methylglyoxal reduces molecular responsiveness to 4 weeks of endurance exercise in mouse plantaris muscle2022

    • Author(s)
      Egawa Tatsuro、Ogawa Takeshi、Yokokawa Takumi、Kido Kohei、Goto Katsumasa、Hayashi Tatsuya
    • Journal Title

      Journal of Applied Physiology

      Volume: 132 Issue: 2 Pages: 477-488

    • DOI

      10.1152/japplphysiol.00539.2021

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19K11520, KAKENHI-PROJECT-19K22806, KAKENHI-PROJECT-19K20007, KAKENHI-PROJECT-18H03160, KAKENHI-PROJECT-20K19498, KAKENHI-PROJECT-19K24330, KAKENHI-PROJECT-19KK0254, KAKENHI-PROJECT-23K21598
  • [Journal Article] Relationship between protein intake and resistance training?induced muscle hypertrophy in middle-aged women: A pilot study2022

    • Author(s)
      Yasuda Jun、Murata Kao、Hasegawa Tsubasa、Yamamura Mana、Maeo Sumiaki、Takegaki Junya、Tottori Nobuaki、Yokokawa Takumi、Mori Risako、Arimitsu Takuma、Nishikori Shu、Fujita Satoshi
    • Journal Title

      Nutrition

      Volume: 97 Pages: 111607-111607

    • DOI

      10.1016/j.nut.2022.111607

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20J01233, KAKENHI-PROJECT-20K19498, KAKENHI-PROJECT-19K24330, KAKENHI-PROJECT-21KK0177, KAKENHI-PROJECT-23K24732
  • [Journal Article] TLR4-Mediated Inflammatory Responses Regulate Exercise-Induced Molecular Adaptations in Mouse Skeletal Muscle2022

    • Author(s)
      Fujiyoshi Haruna、Egawa Tatsuro、Kurogi Eriko、Yokokawa Takumi、Kido Kohei、Hayashi Tatsuya
    • Journal Title

      International Journal of Molecular Sciences

      Volume: 23 Issue: 3 Pages: 1877-1877

    • DOI

      10.3390/ijms23031877

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-19K11520, KAKENHI-PROJECT-19K20007, KAKENHI-PROJECT-20K19498, KAKENHI-PROJECT-19K24330, KAKENHI-PROJECT-23K21598
  • [Journal Article] Disruption of CRTC1 and CRTC2 in Sim1 cells strongly increases high-fat diet intake in female mice but has a modest impact on male mice2022

    • Author(s)
      Tanaka Jin、Ishikawa Fuka、Jinno Tomoki、Miyakita Motoki、Miyamori Haruka、Sasaki Tsutomu、Yokokawa Takumi、Goto Tsuyoshi、Inoue Kazuo、Matsumura Shigenobu
    • Journal Title

      PLOS ONE

      Volume: 17 Issue: 1 Pages: e0262577-e0262577

    • DOI

      10.1371/journal.pone.0262577

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-19H02909, KAKENHI-PROJECT-20K19498, KAKENHI-PROJECT-19K24330
  • [Journal Article] Caffeine increases myoglobin expression via the cyclic AMP pathway in L6 myotubes2021

    • Author(s)
      Takumi Yokokawa, Takeshi Hashimoto, Nobumasa Iwanaka
    • Journal Title

      Physiological Reports

      Volume: 9 Issue: 9 Pages: 1-1

    • DOI

      10.14814/phy2.14869

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-18K19762, KAKENHI-PROJECT-20K11659, KAKENHI-PROJECT-20K19498, KAKENHI-PROJECT-19K24330
  • [Journal Article] Involvement of receptor for advanced glycation end products in microgravity-induced skeletal muscle atrophy in mice2020

    • Author(s)
      Egawa Tatsuro、Kido Kohei、Yokokawa Takumi、Fujibayashi Mami、Goto Katsumasa、Hayashi Tatsuya
    • Journal Title

      Acta Astronautica

      Volume: 176 Pages: 332-340

    • DOI

      10.1016/j.actaastro.2020.07.002

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-19K11520, KAKENHI-PROJECT-19K22806, KAKENHI-PROJECT-19K20007, KAKENHI-PROJECT-20K19498, KAKENHI-PROJECT-19K24330, KAKENHI-PROJECT-18H03148, KAKENHI-PROJECT-18H03160, KAKENHI-PROJECT-19K22825
  • [Journal Article] Muscle denervation reduces mitochondrial biogenesis and mitochondrial translation factor expression in mice2020

    • Author(s)
      Yokokawa Takumi、Mori Risako、Suga Tadashi、Isaka Tadao、Hayashi Tatsuya、Fujita Satoshi
    • Journal Title

      Biochemical and Biophysical Research Communications

      Volume: 527 Issue: 1 Pages: 146-152

    • DOI

      10.1016/j.bbrc.2020.04.062

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17H02183, KAKENHI-PROJECT-19K11520, KAKENHI-PROJECT-20K19498, KAKENHI-PROJECT-19K24330
  • [Journal Article] Modified expression of vitamin D receptor and CYP27B1 in denervation-induced muscle atrophy2020

    • Author(s)
      Mori Risako、Yokokawa Takumi、Fujita Satoshi
    • Journal Title

      Biochemical and Biophysical Research Communications

      Volume: 529 Issue: 3 Pages: 733-739

    • DOI

      10.1016/j.bbrc.2020.05.205

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20K19498, KAKENHI-PROJECT-19K24330, KAKENHI-PROJECT-17H02183
  • [Journal Article] Dehydroepiandrosterone activates 5′-adenosine monophosphate-activated protein kinase and suppresses lipid accumulation and adipocyte differentiation in 3T3-L1 cells2020

    • Author(s)
      Yokokawa Takumi、Sato Koji、Narusawa Ryoko、Kido Kohei、Mori Risako、Iwanaka Nobumasa、Hayashi Tatsuya、Hashimoto Takeshi
    • Journal Title

      Biochemical and Biophysical Research Communications

      Volume: 528 Issue: 3 Pages: 612-619

    • DOI

      10.1016/j.bbrc.2020.05.136

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19K11520, KAKENHI-PROJECT-19K20007, KAKENHI-PROJECT-20K19498, KAKENHI-PROJECT-19K24330, KAKENHI-PROJECT-18K19762
  • [Journal Article] The Protective Effect of Brazilian Propolis against Glycation Stress in Mouse Skeletal Muscle2019

    • Author(s)
      Egawa T, Ohno Y, Yokoyama S, Yokokawa T, Tsuda S, Goto K, Hayashi T.
    • Journal Title

      Foods

      Volume: 8 Issue: 10 Pages: 439-439

    • DOI

      10.3390/foods8100439

    • NAID

      120006766120

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-18K10796, KAKENHI-PROJECT-19K11520, KAKENHI-PROJECT-19K22806, KAKENHI-PROJECT-19K22825, KAKENHI-PROJECT-19K19854, KAKENHI-PROJECT-19K24330, KAKENHI-PROJECT-18H03148, KAKENHI-PROJECT-18H03160, KAKENHI-PROJECT-17K01762
  • [Presentation] 成熟骨格筋におけるインスリン様成長因子1の欠損が骨格筋量および関連シグナル応答に及ぼす影響2024

    • Author(s)
      尾崎主基、横川拓海、江川達郎、井山涼太、林達也、井上和生
    • Organizer
      第38回 日本体力医学会近畿地方会
    • Data Source
      KAKENHI-PROJECT-23K16695
  • [Presentation] 成熟骨格筋におけるインスリン様成長因子1の欠損が 骨格筋量および関連シグナル応答に及ぼす影響2024

    • Author(s)
      尾崎主基、横川拓海、江川達郎、井山涼太、林達也、井上和生.
    • Organizer
      第38回 日本体力医学会近畿地方会
    • Data Source
      KAKENHI-PROJECT-22K19750
  • [Presentation] 成熟骨格筋におけるインスリン様成長因子1の欠損が 骨格筋量および関連シグナル応答に及ぼす影響2024

    • Author(s)
      尾崎主基、横川拓海、江川達郎、井山涼太、林達也、井上和生.
    • Organizer
      第38回日本体力医学会近畿地方会
    • Data Source
      KAKENHI-PROJECT-23K27973
  • [Presentation] 終末糖化産物AGEsによるマウス骨格筋細胞膜脆弱化の誘導2023

    • Author(s)
      江川達郎、小川岳史、木戸康平、横川拓海、後藤勝正、林達也.
    • Organizer
      第69回日本宇宙航空環境医学会大会
    • Data Source
      KAKENHI-PROJECT-22K19750
  • [Presentation] Possible involvement of methylglyoxal as a new exercise-resistance factor2023

    • Author(s)
      江川達郎、小川岳史、木戸康平、横川拓海、後藤勝正、林達也.
    • Organizer
      日本生理学会第100回記念大会
    • Data Source
      KAKENHI-PROJECT-23K27973
  • [Presentation] Possible involvement of methylglyoxal as a new exercise-resistance factor2023

    • Author(s)
      江川達郎、小川岳史、木戸康平、横川拓海、後藤勝正、林達也.
    • Organizer
      日本生理学会第100回記念大会
    • Data Source
      KAKENHI-PROJECT-22K19750
  • [Presentation] 終末糖化産物AGEsによるマウス骨格筋細胞膜脆弱化の誘導2023

    • Author(s)
      江川達郎、小川岳史、木戸康平、横川拓海、後藤勝正、林達也.
    • Organizer
      第69回日本宇宙航空環境医学会大会
    • Data Source
      KAKENHI-PROJECT-23K27973
  • [Presentation] Association between Serum 25-hydroxyvitamin D concentration and muscle mass and strength in Japanese elderly people2020

    • Author(s)
      Yamamura, M., Yasuda, J., Yokokawa, T., & Fujita, S
    • Organizer
      International Conference on Frailty and Sarcopenia Research 2020
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-19K24330
  • [Presentation] マウスにおける経皮的電気刺激によるレジスタンス運動モデルの検討2019

    • Author(s)
      森理紗子, 横川拓海, 藤田聡
    • Organizer
      第74回 日本体力医学会大会
    • Data Source
      KAKENHI-PROJECT-19K24330
  • [Presentation] 骨格筋特異的IGF-I欠損が骨格筋ならびに全身性の代謝に及ぼす影響2019

    • Author(s)
      横川 拓海, 木戸康平, 森理紗子, 佐瀬晃平, 増山律子, 林達也, 藤田 聡
    • Organizer
      第42回日本分子生物学会年会
    • Data Source
      KAKENHI-PROJECT-19K24330
  • [Presentation] ラパマイシンは単回レジスタンス運動に伴う骨格筋のインスリン感受性亢進効果を高める2019

    • Author(s)
      木戸康平, 佐瀬晃平, 横川拓海, 藤田聡
    • Organizer
      第74回 日本体力医学会大会
    • Data Source
      KAKENHI-PROJECT-19K24330
  • [Presentation] 坐骨神経切除による骨格筋萎縮はビタミンD受容体およびCYP27B1のタンパク質発現量の増加を伴う2019

    • Author(s)
      森理紗子, 横川拓海, 藤田聡
    • Organizer
      第42回日本分子生物学会年会
    • Data Source
      KAKENHI-PROJECT-19K24330
  • [Presentation] The influence of combination of Aurantiochytrium intake and resistance exercise on AMPK and mTORC1 signaling in murine skeletal muscle2019

    • Author(s)
      Mori, R., Yokokawa, T., Katamoto, Y., Ishihara, K., Iwata, O., Asayama, Y., Suzuki, K., Fujita, S.
    • Organizer
      24th Annual Congress of the European College of Sport Science
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-19K24330
  • [Presentation] 脱神経がマウス骨格筋におけるミトコンドリア翻訳因子の発現量に及ぼす影響2019

    • Author(s)
      横川拓海, 森理紗子, 菅唯志, 伊坂忠夫, 林達也, 藤田聡
    • Organizer
      第74回 日本体力医学会大会
    • Data Source
      KAKENHI-PROJECT-19K24330
  • [Presentation] Time course effects of voluntary running exercise on protein products of immediate early genes in murine hippocampus2019

    • Author(s)
      Yokokawa, T., Hayashi, T., & Fujita, S.
    • Organizer
      24th Annual Congress of the European College of Sport Science
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-19K24330
  • 1.  江川 達郎 (00722331)
    # of Collaborated Projects: 4 results
    # of Collaborated Products: 6 results
  • 2.  Hayashi Tatsuya (00314211)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 12 results
  • 3.  岩中 伸壮 (80584002)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 4.  岩田 浩明 (40613328)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 5.  後藤 勝正 (70239961)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 6.  FUJITA Satoshi
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 7.  SASAKI Tsutomu
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 2 results
  • 8.  MATSUMURA Shigenobu
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 2 results
  • 9.  OHNO Yoshitaka
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 10.  HASHIMOTO Takeshi
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 11.  佐藤 幸治
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 12.  竹垣 淳也
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results

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