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Emoto Takuo  江本 拓央

ORCIDConnect your ORCID iD *help
Researcher Number 80855023
Other IDs
Affiliation (Current) 2025: 神戸大学, 医学研究科, 医学研究員
Affiliation (based on the past Project Information) *help 2020 – 2024: 神戸大学, 医学研究科, 医学研究員
Review Section/Research Field
Principal Investigator
Basic Section 53020:Cardiology-related
Except Principal Investigator
Basic Section 53020:Cardiology-related / Basic Section 55030:Cardiovascular surgery-related / Basic Section 58040:Forensics medicine-related
Keywords
Principal Investigator
動脈硬化 / 免疫 / 大動脈瘤 / マクロファージ / 慢性冠症候群 / 急性冠症候群 / 冠動脈疾患 / シングルセル解析 / 骨髄ニッチ / 単球 / 骨髄 … More
Except Principal Investigator
… More 動脈硬化 / シングルセル解析 / シングルセルRNAシークエンス / 単一細胞遺伝子発現解析 / 心房細動 / 大動脈解離 / 虚血性心疾患 / シングルセルRNA解析 / 腹部大動脈瘤 / 大動脈瘤 / 右心不全 / 成人先天性心疾患 / 肺動脈弁逆流 / 右室機能不全 / eQTL解析 / マルチオミックス解析 / クローン性造血 / T細胞レパトア解析 / マクロファージ / CellChat解析 / ゲノム・オミックス統合解析 / 免疫細胞 / 好中球 Less
  • Research Projects

    (12 results)
  • Research Products

    (12 results)
  • Co-Researchers

    (11 People)
  •  Genome and single cell transcirptome analyses of atherosclerotic lesions for clarifying the pathophysiology of diseases and developing novel therapies.

    • Principal Investigator
      山下 智也
    • Project Period (FY)
      2024 – 2026
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Review Section
      Basic Section 53020:Cardiology-related
    • Research Institution
      Kobe University
  •  Development of novel immune therapy against abdominal aortic aneurysm.Principal Investigator

    • Principal Investigator
      江本 拓央
    • Project Period (FY)
      2024 – 2026
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Review Section
      Basic Section 53020:Cardiology-related
    • Research Institution
      Kobe University
  •  シングルセル解析による心房細動の炎症病態の解明と新規疾患予防法の開発

    • Principal Investigator
      今村 公威
    • Project Period (FY)
      2024 – 2026
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 53020:Cardiology-related
    • Research Institution
      Kobe University
  •  Clarifying the mechanisms of atherosclerotic cardiovascular diseases via genome and single cell integrated omics analyses.

    • Principal Investigator
      平田 健一
    • Project Period (FY)
      2023 – 2025
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Review Section
      Basic Section 53020:Cardiology-related
    • Research Institution
      Kobe University
  •  Identification of new specific molecules associated with right ventricular dysfunction in adult patients with congenital heart disease

    • Principal Investigator
      福田 旭伸
    • Project Period (FY)
      2023 – 2025
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 53020:Cardiology-related
    • Research Institution
      Kobe University
  •  腹部大動脈瘤の炎症細胞から見る成因解析と新たな治療ターゲットの模索

    • Principal Investigator
      山中 勝弘
    • Project Period (FY)
      2023 – 2025
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 55030:Cardiovascular surgery-related
    • Research Institution
      Kobe University
  •  虚血性心疾患法医剖検例におけるシングルセルRNAシークエンス解析

    • Principal Investigator
      近藤 武史
    • Project Period (FY)
      2023 – 2025
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 58040:Forensics medicine-related
    • Research Institution
      Kobe University
  •  大動脈解離の発生と進展に好中球が与える影響の検討

    • Principal Investigator
      井上 大志
    • Project Period (FY)
      2022 – 2024
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 53020:Cardiology-related
    • Research Institution
      Kobe University
  •  心房細動と炎症の関連を解明するための心房筋炎症免疫細胞の単一細胞遺伝子解析

    • Principal Investigator
      福沢 公二
    • Project Period (FY)
      2022 – 2024
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 53020:Cardiology-related
    • Research Institution
      Kobe University
  •  ヒト大動脈解離におけるシングルセルRNAシークエンスによる成因解析

    • Principal Investigator
      岡田 健次
    • Project Period (FY)
      2022 – 2024
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 55030:Cardiovascular surgery-related
    • Research Institution
      Kobe University
  •  Development of a new therapy targeting macrophagesPrincipal Investigator

    • Principal Investigator
      Takuo Emoto
    • Project Period (FY)
      2022 – 2023
    • Research Category
      Grant-in-Aid for Early-Career Scientists
    • Review Section
      Basic Section 53020:Cardiology-related
    • Research Institution
      Kobe University
  •  Development of bone marrow targeting therapy against atheresclerosisPrincipal Investigator

    • Principal Investigator
      Emoto Takuo
    • Project Period (FY)
      2020 – 2021
    • Research Category
      Grant-in-Aid for Early-Career Scientists
    • Review Section
      Basic Section 53020:Cardiology-related
    • Research Institution
      Kobe University

All 2024 2023 2022

All Journal Article Presentation

  • [Journal Article] Single-Cell RNA Sequencing Reveals an Immune Landscape of CD4 <sup>+</sup> T Cells in Coronary Culprit Plaques With Acute Coronary Syndrome in Humans2024

    • Author(s)
      Takeda Shintaro、Emoto Takuo、Yamashita Tomoya、Yamamoto Hiroyuki、Takaya Tomofumi、Sawada Takahiro、Yoshida Takeshi、Inoue Masatoshi、Suzuki Yuya、Hamana Tomoyo、Inoue Taishi、Taniguchi Masayuki、Sasaki Naoto、Otake Hiromasa、Ohkawa Takenao、Furuyashiki Tomoyuki、Kawai Hiroya、Hirata Ken-ichi
    • Journal Title

      Arteriosclerosis, Thrombosis, and Vascular Biology

      Volume: - Issue: 5 Pages: 1135-1143

    • DOI

      10.1161/atvbaha.123.320409

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-23K06359, KAKENHI-PROJECT-22K16105, KAKENHI-PUBLICLY-23H04234, KAKENHI-PROJECT-21H04812, KAKENHI-PROJECT-23K27596
  • [Journal Article] Single-Cell RNA Sequencing Reveals a Distinct Immune Landscape of Myeloid Cells in Coronary Culprit Plaques Causing Acute Coronary Syndrome2022

    • Author(s)
      Emoto Takuo、Yamamoto Hiroyuki、Yamashita Tomoya、Takaya Tomofumi、Sawada Takahiro、Takeda Shintaro、Taniguchi Masayuki、Sasaki Naoto、Yoshida Naofumi、Saito Yoshihiro、Sivasubramaniyam Tharini、Otake Hiromasa、Furuyashiki Tomoyuki、Robbins Clinton S.、Kawai Hiroya、Hirata Ken-ichi
    • Journal Title

      Circulation

      Volume: 145 Issue: 18 Pages: 1434-1436

    • DOI

      10.1161/circulationaha.121.058414

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-20K17152, KAKENHI-PROJECT-21K15268, KAKENHI-PROJECT-21H04812, KAKENHI-PLANNED-18H05429
  • [Presentation] Intense Impact of Immune Cells on Aortic Valve Stenosis2024

    • Author(s)
      Takuo Emoto
    • Organizer
      第88回 日本循環器学会学術集会
    • Data Source
      KAKENHI-PROJECT-23K27596
  • [Presentation] Difference between ACS and CCS culprit lesions: Lessons from Single cell RNA Sequence Analysis2024

    • Author(s)
      江本拓央
    • Organizer
      日本循環器学会
    • Data Source
      KAKENHI-PROJECT-22K16105
  • [Presentation] Difference between ACS and CCS culprit lesions: Lessons from Single cell RNA-Seq Analysis2024

    • Author(s)
      Takuo Emoto
    • Organizer
      第88回 日本循環器学会学術集会
    • Data Source
      KAKENHI-PROJECT-23K27596
  • [Presentation] Single Cell RNA Sequencing Reveals a Distinct Immune Landscape in the Left Atria in Atrial Fibrillation Patients2023

    • Author(s)
      鈴木雄也,江本拓央,佐藤俊輔,遠藤広美,井上大志,林友鴻,仁田英里子,小西弘樹,木内邦彦,髙見充,谷口将之,古屋敷智之,仁田亮,山下智也,平田健一,福沢公二
    • Organizer
      第71回日本心臓病学会学術集会
    • Data Source
      KAKENHI-PROJECT-22K08206
  • [Presentation] シングルセル解析で解き明かすプラーク不安定化メカニズム2023

    • Author(s)
      江本拓央、山下智也、平田健一
    • Organizer
      第55回日本動脈硬化学会総会・学術集会
    • Data Source
      KAKENHI-PROJECT-23K27596
  • [Presentation] タバコ腹部大動脈瘤モデルの開発と新たな治療戦略に向けて2023

    • Author(s)
      江本拓央、山下智也、平田健一、Clinton Robbins
    • Organizer
      第55回日本動脈硬化学会総会・学術集会
    • Data Source
      KAKENHI-PROJECT-23K27596
  • [Presentation] シングルセル解析で解き明かすプラーク不安定化メカニズム2023

    • Author(s)
      江本拓央
    • Organizer
      動脈硬化学会
    • Data Source
      KAKENHI-PROJECT-22K16105
  • [Presentation] Immune Cell Landscape of Coronary Culprit Plaques Causing Acute Coronary Syndrome.2022

    • Author(s)
      Takuo Emoto
    • Organizer
      CSC Joint Sessions-the 24th Congress of the Chinese Society of Cardiology
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-22K16105
  • [Presentation] 急性冠症候群を発症した冠動脈プラーク内免疫細胞のシングルセル解析2022

    • Author(s)
      江本拓央
    • Organizer
      第50回日本臨床免疫学会
    • Data Source
      KAKENHI-PROJECT-22K16105
  • [Presentation] 急性冠症候群を発症する冠動脈プラーク免疫細胞の特徴2022

    • Author(s)
      江本拓央
    • Organizer
      NGS EXPO 2022
    • Data Source
      KAKENHI-PROJECT-22K16105
  • 1.  山下 智也 (90437468)
    # of Collaborated Projects: 6 results
    # of Collaborated Products: 2 results
  • 2.  井上 大志 (50868487)
    # of Collaborated Projects: 5 results
    # of Collaborated Products: 0 results
  • 3.  山中 勝弘 (70729384)
    # of Collaborated Projects: 5 results
    # of Collaborated Products: 0 results
  • 4.  岡田 健次 (90284356)
    # of Collaborated Projects: 5 results
    # of Collaborated Products: 0 results
  • 5.  福沢 公二 (70535856)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 1 results
  • 6.  今村 公威 (20791221)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 7.  平田 健一 (20283880)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 2 results
  • 8.  大竹 寛雅 (60593803)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 9.  福田 旭伸 (70791086)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 10.  近藤 武史 (20335441)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 11.  谷口 将之
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results

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