Abo Hirohito 安保博仁

Researcher Number	80868050
Other IDs
Affiliation (based on the past Project Information) *help	2020 – 2023: 千葉大学, 大学院薬学研究院, 助教
Review Section/Research Field	Principal Investigator Basic Section 47030:Pharmaceutical hygiene and biochemistry-related Except Principal Investigator Basic Section 47030:Pharmaceutical hygiene and biochemistry-related
Keywords	Principal Investigator 腸内細菌 / 硫酸化修飾 / 糖鎖 / 腸管免疫 / 炎症性腸疾患 / 硫酸化糖鎖 / 免疫 / 腸内細菌叢 / 代謝 / 大腸癌 / 肥満 … More Except Principal Investigator … More 免疫疾患 / 多発性硬化症 / 抗糖鎖抗体 / 高内皮細静脈 / リンパ球ホーミング Less

ムチン糖鎖硫酸化修飾と腸内細菌を基軸とした代謝関連疾患の基盤的研究Principal Investigator
- Principal Investigator
  
  安保博仁
- Project Period (FY)
  2023
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 47030:Pharmaceutical hygiene and biochemistry-related
- Research Institution
  Chiba University
Fundamental research for the development of a novel anti-glycan antibody drug against multiple sclerosis
- Principal Investigator
  
  KAWASHIMA Hiroto
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 47030:Pharmaceutical hygiene and biochemistry-related
- Research Institution
  Chiba University
Analysis of sulfated glycans on mucins in intestinal inflammationPrincipal Investigator
- Principal Investigator
  
  Abo Hirohito
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 47030:Pharmaceutical hygiene and biochemistry-related
- Research Institution
  Chiba University

All 2023 2022 2021 2020

All Journal Article Presentation

[Journal Article] N-acetylglucosamine-6-O-sulfation on intestinal mucins prevents obesity and intestinal inflammation by regulating gut microbiota.2023
- Author(s)
  Abo H, Muraki A, Harusato A, Imura T, Suzuki M, Takahashi K, Denning TL, Kawashima H.
- Journal Title
  
  JCI Insight
  
  Volume: 8 Issue: 16 Pages: 165944-165944
- DOI
  10.1172/jci.insight.165944
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23K18173, KAKENHI-PROJECT-22K11731, KAKENHI-PROJECT-23K14342
[Journal Article] Significance of Sulfated Glycans on Mucins in the Gut2023
- Author(s)
  Abo Hirohito、Kawashima Hiroto
- Journal Title
  
  Trends in Glycoscience and Glycotechnology
  
  Volume: 35 Issue: 207 Pages: J73-J77
- DOI
  10.4052/tigg.2219.1J
- ISSN
  0915-7352, 1883-2113
- Year and Date
  2023-09-25
- Language
  Japanese
- Data Source
  KAKENHI-PROJECT-23K14342
[Journal Article] Therapeutic Effects of an Anti-Sialyl Lewis x Antibody in a Murine Model of Acute Lung Injury.2023
- Author(s)
  Liu W, Xiong W, Liu W, Wei Z, Abo H, Kawashima H.
- Journal Title
  
  Monoclon. Antib. Immunodiagn. Immunother.
  
  Volume: 42 Issue: 3 Pages: 97-103
- DOI
  10.1089/mab.2023.0001
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23K18173, KAKENHI-PROJECT-23K14342
[Journal Article] Identification of crucial amino acid residues for antimicrobial activity of angiogenin 4 and its modulation of gut microbiota in mice.2022
- Author(s)
  Sultana MF, Suzuki M, Yamasaki F, Kubota W, Takahashi K, Abo H and Kawashima H.
- Journal Title
  
  Front. Microbiol.
  
  Volume: 13 Pages: 900948-900948
- DOI
  10.3389/fmicb.2022.900948
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20H03379, KAKENHI-PROJECT-20K15986
[Journal Article] Tumor-associated neutrophils and macrophages exacerbate antidrug IgG-mediated anaphylactic reaction against an immune checkpoint inhibitor2022
- Author(s)
  Arai Takahiro、Kokubo Tomomi、Tang Ruiheng、Abo Hirohito、Terui Ayu、Hirakawa Jotaro、Akita Hidetaka、Kawashima Hiroto、Hisaka Akihiro、Hatakeyama Hiroto
- Journal Title
  
  Journal for ImmunoTherapy of Cancer
  
  Volume: 10 Issue: 12 Pages: e005657-e005657
- DOI
  10.1136/jitc-2022-005657
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PUBLICLY-21H05506, KAKENHI-PROJECT-20H03379, KAKENHI-PROJECT-20K15986
[Journal Article] Human and mouse angiogenins: Emerging insights and potential opportunities.2022
- Author(s)
  Sultana MF, Abo H and Kawashima H.
- Journal Title
  
  Front. Microbiol.
  
  Volume: 12 Pages: 1022945-1022945
- DOI
  10.3389/fmicb.2022.1022945
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20H03379, KAKENHI-PROJECT-20K15986
[Journal Article] Establishment of a novel monoclonal antibody against truncated glycoforms of α-dystroglycan lacking matriglycans2021
- Author(s)
  Yamasaki Fumiya、Umezawa Fumiko、Sensui Tomohiro、Anzo Masashi、Abo Hirohito、Kuo Chu-Wei、Khoo Kay-Hooi、Kato Koichi、Yagi Hirokazu、Kawashima Hiroto
- Journal Title
  
  Biochemical and Biophysical Research Communications
  
  Volume: 579 Pages: 8-14
- DOI
  10.1016/j.bbrc.2021.09.043
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-17H06414, KAKENHI-PROJECT-20H03379, KAKENHI-PROJECT-23K21358, KAKENHI-PROJECT-20K15986
[Presentation] Expression and function of sialyl Lewis X glycans on mouse regulatoly T cells2022
- Author(s)
  Kanae Ohishi, Shogo Nshida, Asaki Ishikura, Hirohito Abo, Hiroko Nakatsukasa, Hiroto Kawashima
- Organizer
  第51回日本免疫学会学術総会
- Data Source
  KAKENHI-PROJECT-20H03379
[Presentation] 制御性T細胞表面シアリルルイスX糖鎖抗原の炎症における役割の解明2022
- Author(s)
  大石かなえ、西田匠吾、石倉晨規、安保博仁、中司寛子、川島博人
- Organizer
  第21回ファーマ・バイオフォーラム
- Data Source
  KAKENHI-PROJECT-20H03379
[Presentation] Expression and function of sialyl Lewis X glycans on mouse regulatoly T cells.2022
- Author(s)
  Kanae Ohishi, Shogo Nshida, Asaki Ishikura, Hirohito Abo, Hiroto Kawashima
- Organizer
  Sialoglyco 2022
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20H03379
[Presentation] Sulfated Glycan-Mediated Regulation of Intestinal Inflammation and tumorigenesis2021
- Author(s)
  安保博仁
- Organizer
  日本薬学会　関東支部会
- Invited
- Data Source
  KAKENHI-PROJECT-20K15986
[Presentation] ムチン硫酸化による生体防御2021
- Author(s)
  安保博仁、川島博人
- Organizer
  日本薬学会関東支部会第14回若手シンポジウム
- Invited
- Data Source
  KAKENHI-PROJECT-20H03379
[Presentation] マトリグリカン欠損ジストログリカンに対する新規モノクローナル抗体の樹立2021
- Author(s)
  山崎郁弥、梅澤芙美子、安藏匡史、安保博仁、加藤晃一、矢木宏和、川島博人
- Organizer
  第94回日本生化学会大会
- Data Source
  KAKENHI-PROJECT-20H03379
[Presentation] 制御性T細胞表面シアリルルイスX糖鎖抗原の炎症における役割2021
- Author(s)
  大石かなえ、西田匠吾、石倉晨規、安保博仁、川島博人
- Organizer
  第21回 Pharmaco-Hematology シンポジウム
- Data Source
  KAKENHI-PROJECT-20H03379
[Presentation] シアリルルイスX糖鎖抗原を発現する制御性T細胞の体内動態と機能2021
- Author(s)
  大石かなえ、西田匠吾、石倉晨規、安保博仁、川島博人
- Organizer
  GlycoTOKYO2021
- Data Source
  KAKENHI-PROJECT-20H03379
[Presentation] 制御性T細胞表面シアリルルイスX糖鎖抗原の炎症に伴う発現変化と機能の解析2020
- Author(s)
  西田匠吾、竹添知宏、関根成隆、込山大智、安保博仁、川島博人
- Organizer
  第39回日本糖質学会年会
- Data Source
  KAKENHI-PROJECT-20H03379
[Presentation] LPS誘発性急性肺損傷における抗シアリルルイスX糖鎖抗体の治療効果の解析2020
- Author(s)
  Liu Wenxin、熊　偉、安保　博仁、川島　博人
- Organizer
  日本薬学会第１４１年会
- Data Source
  KAKENHI-PROJECT-20H03379
[Presentation] 制御性T細胞表面シアリルルイスX糖鎖抗原の炎症に伴う発現変化2020
- Author(s)
  西田匠吾、竹添知宏、関根成隆、込山大智、安保博仁、川島博人
- Organizer
  第93回日本生化学会大会
- Data Source
  KAKENHI-PROJECT-20H03379

1. KAWASHIMA Hiroto (50260336)

# of Collaborated Projects: 1 results

# of Collaborated Products: 14 results
2. 小林基弘 (00362137)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
3. YAGI Hirokazu

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
4. 畠山浩人

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Abo Hirohito 安保 博仁

Research Projects

Research Products

Co-Researchers

ムチン糖鎖硫酸化修飾と腸内細菌を基軸とした代謝関連疾患の基盤的研究Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Fundamental research for the development of a novel anti-glycan antibody drug against multiple sclerosis

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Analysis of sulfated glycans on mucins in intestinal inflammationPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

[Journal Article] N-acetylglucosamine-6-O-sulfation on intestinal mucins prevents obesity and intestinal inflammation by regulating gut microbiota.2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Significance of Sulfated Glycans on Mucins in the Gut2023

Author(s)

Journal Title

DOI

ISSN

Year and Date

Language

Data Source

[Journal Article] Therapeutic Effects of an Anti-Sialyl Lewis x Antibody in a Murine Model of Acute Lung Injury.2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Identification of crucial amino acid residues for antimicrobial activity of angiogenin 4 and its modulation of gut microbiota in mice.2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Tumor-associated neutrophils and macrophages exacerbate antidrug IgG-mediated anaphylactic reaction against an immune checkpoint inhibitor2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Human and mouse angiogenins: Emerging insights and potential opportunities.2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Establishment of a novel monoclonal antibody against truncated glycoforms of α-dystroglycan lacking matriglycans2021

Author(s)

Journal Title

DOI

Data Source

[Presentation] Expression and function of sialyl Lewis X glycans on mouse regulatoly T cells2022

Author(s)

Organizer

Data Source

[Presentation] 制御性T細胞表面シアリルルイスX糖鎖抗原の炎症における役割の解明2022

Author(s)

Organizer

Data Source

[Presentation] Expression and function of sialyl Lewis X glycans on mouse regulatoly T cells.2022

Author(s)

Organizer

Data Source

[Presentation] Sulfated Glycan-Mediated Regulation of Intestinal Inflammation and tumorigenesis2021

Author(s)

Organizer

Data Source

[Presentation] ムチン硫酸化による生体防御2021

Author(s)

Organizer

Data Source

Abo Hirohito 安保博仁