HIGUCHI Yusuke 樋口悠介

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Higuchi Yusuke 樋口悠介

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Researcher Number	80882141
Other IDs
Affiliation (Current)	2025: 熊本大学, 大学院生命科学研究部(医), 特定研究員
Affiliation (based on the past Project Information) *help	2020 – 2023: 熊本大学, 病院, 助教
Review Section/Research Field	Principal Investigator Basic Section 54010:Hematology and medical oncology-related / 0902:General internal medicine and related fields
Keywords	Principal Investigator HBZ / HTLV-1 / JDP2 / STAT1 / HTV-1 / STAT3 / IL-10

HBZ-宿主タンパク質結合のATL発がん機序における役割の解明Principal Investigator
- Principal Investigator
  
  樋口悠介
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 54010:Hematology and medical oncology-related
- Research Institution
  Kumamoto University
The mechanisms for oncogenesis induced by HTLV-1-mediated modulation of cytokine signalingPrincipal Investigator
- Principal Investigator
  
  Higuchi Yusuke
- Project Period (FY)
  2020 – 2021
- Research Category
  
  Grant-in-Aid for Research Activity Start-up
- Review Section
  
  0902:General internal medicine and related fields
- Research Institution
  Kumamoto University

All 2023 2022 2020

All Journal Article Presentation

[Journal Article] Robust prognostic value of histologic transformation in patients with early progression of follicular lymphoma2023
- Author(s)
  Shichijo Takafumi、Tatetsu Hiro、Nosaka Kisato、Higuchi Yusuke、Kikukawa Yoshitaka、Toyoda Kosuke、Shiraishi Shinya、Yasunaga Jun-ichirou、Matsuoka Masao
- Journal Title
  
  Leukemia & Lymphoma
  
  Volume: 64 Issue: 10 Pages: 1706-1710
- DOI
  10.1080/10428194.2023.2226429
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K16325, KAKENHI-PROJECT-23K15303, KAKENHI-PROJECT-21K08420, KAKENHI-PROJECT-20H03514
[Journal Article] Waldenstrom's macroglobulinemia-like B cell lymphoma with MYD88 L265P mutation and t(14;18)(q32;q21) involving IGH-MALT12023
- Author(s)
  Furuta Rie、Tatetsu Hiro、Yasunaga Jun-ichirou、Ueno Mitsunori、Oshiro Kento、Kumanomido Satoshi、Kawano Yawara、Higuchi Yusuke、Honda Yumi、Mikami Yoshiki、Nosaka Kisato、Matsuoka Masao
- Journal Title
  
  Leukemia Research Reports
  
  Volume: 20 Pages: 100389-100389
- DOI
  10.1016/j.lrr.2023.100389
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K16325, KAKENHI-PROJECT-21K08420, KAKENHI-PROJECT-20H03514
[Journal Article] Significant response of patients with transformed follicular lymphoma with rapid disease progression to CAR-T therapy2023
- Author(s)
  Hirano Taichi、Tatetsu Hiro、Ueno Shikiko、Shichijo Takafumi、Furukawa Shota、Tsujihashi Mizuho、Miyakawa Toshikazu、Shiraishi Shinya、Higuchi Yusuke、Uchiba Mitsuhiro、Yasunaga Jun-ichirou、Nosaka Kisato、Matsuoka Masao
- Journal Title
  
  Journal of Clinical and Experimental Hematopathology
  
  Volume: 63 Issue: 4 Pages: 266-269
- DOI
  10.3960/jslrt.23033
- ISSN
  1346-4280, 1880-9952
- Language
  English
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K16325, KAKENHI-PROJECT-23K15303, KAKENHI-PROJECT-21K08420, KAKENHI-PROJECT-20H03514
[Journal Article] Prophylactic effect of tixagevimab-cilgavimab on COVID-19 infection and death in Japanese patients with B cell lymphoma2023
- Author(s)
  Tatetsu Hiro、Higuchi Yusuke、Shichijo Takafumi、Oda Kazutaka、Nakata Hirotomo、Yasunaga Jun-ichirou、Nosaka Kisato、Matsuoka Masao
- Journal Title
  
  International Journal of Hematology
  
  Volume: 118 Issue: 2 Pages: 303-305
- DOI
  10.1007/s12185-023-03629-4
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K16325, KAKENHI-PROJECT-23K15303, KAKENHI-PROJECT-21K08420, KAKENHI-PROJECT-20H03514
[Journal Article] Beneficial impact of first‐line mogamulizumab‐containing chemotherapy in adult T‐cell leukaemia‐lymphoma2022
- Author(s)
  Shichijo Takafumi、Nosaka Kisato、Tatetsu Hiro、Higuchi Yusuke、Endo Shinya、Inoue Yoshitaka、Toyoda Kosuke、Kikukawa Yoshitaka、Kawakita Toshiro、Yasunaga Jun‐ichirou、Matsuoka Masao
- Journal Title
  
  British Journal of Haematology
  
  Volume: 198 Issue: 6 Pages: 983-987
- DOI
  10.1111/bjh.18281
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K08420, KAKENHI-PROJECT-22K16325, KAKENHI-PROJECT-19H03689, KAKENHI-PROJECT-20H03514
[Journal Article] HTLV-1's Foxy Strategy for Survival and Transmission2022
- Author(s)
  Higuchi Yusuke、Yasunaga Jun-ichirou、Matsuoka Masao
- Journal Title
  
  Frontiers in Virology
  
  Volume: 1
- DOI
  10.3389/fviro.2021.792659
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K22904
[Journal Article] Predictive impact of soluble interleukin‐2 receptor and number of extranodal sites for identification of patients at very high risk of CNS relapse in diffuse large B‐cell lymphoma2022
- Author(s)
  Shichijo Takafumi、Tatetsu Hiro、Nosaka Kisato、Higuchi Yusuke、Kikukawa Yoshitaka、Inoue Yoshitaka、Toyoda Kosuke、Yasunaga Jun‐ichirou、Matsuoka Masao
- Journal Title
  
  eJHaem
  
  Volume: - Issue: 2 Pages: 385-393
- DOI
  10.1002/jha2.393
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K22904, KAKENHI-PROJECT-21K08420, KAKENHI-PROJECT-22K16325, KAKENHI-PROJECT-19H03689, KAKENHI-PROJECT-20H03514
[Journal Article] HTLV-1 induces T cell malignancy and inflammation by viral antisense factor-mediated modulation of the cytokine signaling2020
- Author(s)
  Higuchi Yusuke、Yasunaga Jun-ichirou、Mitagami Yu、Tsukamoto Hirotake、Nakashima Kazutaka、Ohshima Koichi、Matsuoka Masao
- Journal Title
  
  Proceedings of the National Academy of Sciences
  
  Volume: 117 Issue: 24 Pages: 13740-13749
- DOI
  10.1073/pnas.1922884117
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K22904, KAKENHI-PROJECT-19H03689, KAKENHI-PROJECT-18K07325, KAKENHI-PROJECT-20H03514
[Journal Article] Safety and pharmacokinetics of polatuzumab vedotin in Japanese patients with relapsed/refractory B-cell non-Hodgkin lymphoma: a phase 1 dose-escalation study2020
- Author(s)
  Kinoshita Tomohiro、Hatake Kiyohiko、Yamamoto Kazuhito、Higuchi Yusuke、Murakami Satsuki、Terui Yasuhito、Yokoyama Masahiro、Maruyama Dai、Makita Shinichi、Hida Yukari、Saito Tomohisa、Tobinai Kensei
- Journal Title
  
  Japanese Journal of Clinical Oncology
  
  Volume: 51 Issue: 1 Pages: 70-77
- DOI
  10.1093/jjco/hyaa169
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K22904
[Presentation] Prophylactic effect of tixagevimab-cilgavimab on COVID-19 infection in B-cell lymphoma2023
- Author(s)
  Kisato Nosaka, Hiro Tatetsu , Yusuke Higuchi, Takafumi Shichijo, Kazutaka Oda，Hirotomo Nakata, Jun ichirou Yasunaga, Masao Matsuoka
- Organizer
  第85回日本血液学会学術集会
- Data Source
  KAKENHI-PROJECT-22K16325
[Presentation] Impact of sensitivity to 2nd and 3rd line therapy in refractory/relapsed large B-cell lymphoma2023
- Author(s)
  Hiro Tatetsu, Takafumi Shichijo, Kisato Nosaka, Yusuke Higuchi, Junichirou Yasunaga, Masao Matsuoka
- Organizer
  第85回日本血液学会学術集会
- Data Source
  KAKENHI-PROJECT-22K16325
[Presentation] 診断に苦慮したATLL with HTLV-1-infected HRS-like cellsの1例2023
- Author(s)
  野坂生郷、立津央、樋口悠介、古川翔大、七條敬文、安永純一朗、川上史、三上芳喜、加留部謙之輔、松岡雅雄
- Organizer
  第63回日本リンパ網内系学会総会
- Data Source
  KAKENHI-PROJECT-22K16325
[Presentation] Effect of CAR-T therapy on LBCL patients with progression disease (PD) just before infusion2023
- Author(s)
  平野太一，立津央，樋口悠介，七條敬文，上野志貴子，安永純一朗，野坂生郷，松岡雅雄
- Organizer
  第85回日本血液学会学術集会
- Data Source
  KAKENHI-PROJECT-22K16325
[Presentation] EBV-associated T and B cell lymphoproliferative disorder after autologous PBSCT for B cell lymphoma2023
- Author(s)
  Mikiko Izaki, Hiro Tatetsu, Kiho Yokoo, Hotaka Namie, Himari Kudo, Yusuke Higuchi, Takafumi Shichijo, Junichirou Yasunaga, Yoshiki Mikami, Kisato Nosaka, Masao Matsuoka
- Organizer
  第85回日本血液学会学術集会
- Data Source
  KAKENHI-PROJECT-22K16325
[Presentation] HBZはSTAT1/3との結合を介して，IL-10/JAK/STATシグナル経路を変調させる2020
- Author(s)
  樋口　悠介, 安永　純一朗, 三田上　侑, 大島　孝一, 松岡　雅雄
- Organizer
  第82回日本血液学会学術集会
- Data Source
  KAKENHI-PROJECT-20K22904
[Presentation] HTLV-1関連疾患におけるプロウイルス構造と宿主免疫の違い2020
- Author(s)
  山田麻美, 七條敬文, 樋口悠介, 安永純一朗, 野坂生郷, 松岡雅雄, 中川正法
- Organizer
  第82回日本血液学会学術集会
- Data Source
  KAKENHI-PROJECT-20K22904

1. TATETSU Hiro

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

HIGUCHI Yusuke 樋口 悠介

Higuchi Yusuke 樋口 悠介

Research Projects

Research Products

Co-Researchers

HBZ-宿主タンパク質結合のATL発がん機序における役割の解明Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

The mechanisms for oncogenesis induced by HTLV-1-mediated modulation of cytokine signalingPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

[Journal Article] Robust prognostic value of histologic transformation in patients with early progression of follicular lymphoma2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Waldenstrom's macroglobulinemia-like B cell lymphoma with MYD88 L265P mutation and t(14;18)(q32;q21) involving IGH-MALT12023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Significant response of patients with transformed follicular lymphoma with rapid disease progression to CAR-T therapy2023

Author(s)

Journal Title

DOI

ISSN

Language

Data Source

[Journal Article] Prophylactic effect of tixagevimab-cilgavimab on COVID-19 infection and death in Japanese patients with B cell lymphoma2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Beneficial impact of first‐line mogamulizumab‐containing chemotherapy in adult T‐cell leukaemia‐lymphoma2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] HTLV-1's Foxy Strategy for Survival and Transmission2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Predictive impact of soluble interleukin‐2 receptor and number of extranodal sites for identification of patients at very high risk of CNS relapse in diffuse large B‐cell lymphoma2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] HTLV-1 induces T cell malignancy and inflammation by viral antisense factor-mediated modulation of the cytokine signaling2020

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Safety and pharmacokinetics of polatuzumab vedotin in Japanese patients with relapsed/refractory B-cell non-Hodgkin lymphoma: a phase 1 dose-escalation study2020

Author(s)

Journal Title

DOI

Data Source

[Presentation] Prophylactic effect of tixagevimab-cilgavimab on COVID-19 infection in B-cell lymphoma2023

Author(s)

Organizer

Data Source

[Presentation] Impact of sensitivity to 2nd and 3rd line therapy in refractory/relapsed large B-cell lymphoma2023

Author(s)

Organizer

Data Source

[Presentation] 診断に苦慮したATLL with HTLV-1-infected HRS-like cellsの1例2023

Author(s)

Organizer

Data Source

[Presentation] Effect of CAR-T therapy on LBCL patients with progression disease (PD) just before infusion2023

Author(s)

Organizer

Data Source

HIGUCHI Yusuke 樋口悠介

Higuchi Yusuke 樋口悠介