Fukasawa Takemichi 深澤毅倫

Researcher Number	80884056
Affiliation (Current)	2025: 東京大学, 医学部附属病院, 特任講師
Affiliation (based on the past Project Information) *help	2022 – 2023: 東京大学, 医学部附属病院, 特任講師 2020 – 2021: 東京大学, 医学部附属病院, 助教
Review Section/Research Field	Principal Investigator Basic Section 53050:Dermatology-related / 0903:Organ-based internal medicine and related fields
Keywords	Principal Investigator 医工連携 / B細胞 / T細胞 / 全身性強皮症 / サイトカイン / 自己反応性B細胞 / 新規治療 / モデルマウス / affinity / 単一細胞解析 / microfluidics

Single-cell analysis of autoantigen-reactive B cells in systemic sclerosis and development of novel therapeutic targetsPrincipal Investigator
- Principal Investigator
  
  深澤毅倫
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 53050:Dermatology-related
- Research Institution
  The University of Tokyo
Analysis of the effect of cytokine production by autoantigen-reactive B cells in systemic sclerosis on other immune systems.Principal Investigator
- Principal Investigator
  
  Fukasawa Takemichi
- Project Period (FY)
  2020 – 2021
- Research Category
  
  Grant-in-Aid for Research Activity Start-up
- Review Section
  
  0903:Organ-based internal medicine and related fields
- Research Institution
  The University of Tokyo

All 2024 2023 2022 2021

All Journal Article Presentation Book

[Book] 「臨床と研究」2022
- Author(s)
  深澤毅倫、吉崎歩、佐藤伸一
- Total Pages
  5
- Publisher
  大道学館出版部
- Data Source
  KAKENHI-PROJECT-20K22925
[Book] 皮膚科　膠原病　皮疹から全身を診る2021
- Author(s)
  深澤毅倫
- Total Pages
  5
- Publisher
  中山書店
- Data Source
  KAKENHI-PROJECT-20K22925
[Journal Article] Deregulated JNK signaling enhances apoptosis during hyperthermia2024
- Author(s)
  Enomoto Atsushi、Fukasawa Takemichi、Terunuma Hiroshi、Nakagawa Keiichi、Yoshizaki Ayumi、Sato Shinichi、Hosoya Noriko、Miyagawa Kiyoshi
- Journal Title
  
  International Journal of Hyperthermia
  
  Volume: 41 Issue: 1 Pages: 2335199-2335199
- DOI
  10.1080/02656736.2024.2335199
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K16258, KAKENHI-PROJECT-23K07055, KAKENHI-PROJECT-23K07078
[Journal Article] Cannabinoids for the treatment of autoimmune and inflammatory skin diseases: A systematic review2024
- Author(s)
  Kuzumi Ai、Yamashita Takashi、Fukasawa Takemichi、Yoshizaki‐Ogawa Asako、Sato Shinichi、Yoshizaki Ayumi
- Journal Title
  
  Experimental Dermatology
  
  Volume: 33 Issue: 3
- DOI
  10.1111/exd.15064
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K16258, KAKENHI-PROJECT-22K16259
[Journal Article] Dual blockade of interleukin-17A and interleukin-17F as a therapeutic strategy for liver fibrosis: Investigating the potential effect and mechanism of brodalumab2024
- Author(s)
  Matsuda Kazuki M.、Kotani Hirohito、Hisamoto Teruyoshi、Kuzumi Ai、Fukasawa Takemichi、Yoshizaki-Ogawa Asako、Sato Shinichi、Yoshizaki Ayumi
- Journal Title
  
  Cytokine
  
  Volume: 178 Pages: 156587-156587
- DOI
  10.1016/j.cyto.2024.156587
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K16258, KAKENHI-PROJECT-22K16259, KAKENHI-PROJECT-22K08425
[Journal Article] Reliability, validity, and sensitivity of the Japanese version of the University of California Los Angeles scleroderma clinical trial consortium gastrointestinal tract instrument: Application to efficacy assessment of intravenous immunoglobulin administration2024
- Author(s)
  Matsuda Kazuki M.、Sugimoto Eiki、Ako Yoshiaki、Kitamura Marie、Miyahara Mai、Kotani Hirohito、Norimatsu Yuta、Hisamoto Teruyoshi、Kuzumi Ai、Fukasawa Takemichi、Sato Shinichi、Yoshizaki Ayumi
- Journal Title
  
  The Journal of Dermatology
  
  Volume: - Issue: 6 Pages: 741-751
- DOI
  10.1111/1346-8138.17202
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K16258, KAKENHI-PROJECT-22K16259
[Journal Article] Autoantibodies to nuclear valosin-containing protein-like protein: systemic sclerosis-specific antibodies revealed by in vitro human proteome2024
- Author(s)
  Matsuda Kazuki M, Fukasawa Takemichi et al.
- Journal Title
  
  Rheumatology
  
  Volume: - Issue: 10 Pages: 2865-2873
- DOI
  10.1093/rheumatology/keae063
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K16258, KAKENHI-PROJECT-22K16259, KAKENHI-PROJECT-22K08425, KAKENHI-PROJECT-21H02939
[Journal Article] The role of B cells in systemic sclerosis2024
- Author(s)
  Fukasawa Takemichi、Yoshizaki‐Ogawa Asako、Sato Shinichi、Yoshizaki Ayumi
- Journal Title
  
  The Journal of Dermatology
  
  Volume: - Issue: 7 Pages: 904-913
- DOI
  10.1111/1346-8138.17134
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K16258, KAKENHI-PROJECT-22K08425, KAKENHI-PROJECT-21H02939
[Journal Article] Significance of anti-transcobalamin receptor antibodies in cutaneous arteritis revealed by proteome-wide autoantibody screening2023
- Author(s)
  Matsuda K, Kotani H, Yoshizaki A, et al.
- Journal Title
  
  Journal of Autoimmunity
  
  Volume: 135 Pages: 102995-102995
- DOI
  10.1016/j.jaut.2023.102995
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K08425, KAKENHI-PROJECT-22K16259, KAKENHI-PROJECT-21H02939, KAKENHI-PROJECT-21K19472, KAKENHI-PROJECT-22K16258
[Journal Article] The role of STK38 in DNA damage response and targeting for radio-sensitization.2023
- Author(s)
  T. Fukasawa, A. Enomoto, A. Yoshizaki-Ogawa, S. Sato, K. Miyagawa, A. Yoshizaki.
- Journal Title
  
  Cancers
  
  Volume: 15 Issue: 7 Pages: 2054-2054
- DOI
  10.3390/cancers15072054
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K08100, KAKENHI-PROJECT-22K16258
[Journal Article] Interleukin-17 pathway inhibition with brodalumab in early systemic sclerosis: analysis of a single-arm, open-label, phase 1 trial2023
- Author(s)
  Fukasawa Takemichi、Yoshizaki Ayumi、Ebata Satoshi、Fukayama Maiko、Kuzumi Ai、Norimatsu Yuta、Matsuda Kazuki M、Kotani Hirohito、Sumida Hayakazu、Yoshizaki-Ogawa Asako、Kagebayashi Hisashi、Sato Shinichi
- Journal Title
  
  Journal of the American Academy of Dermatology
  
  Volume: - Issue: 2 Pages: 366-369
- DOI
  10.1016/j.jaad.2023.02.061
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K16258, KAKENHI-PROJECT-22K16259
[Journal Article] The optimal use of tildrakizumab in the elderly via improvement of Treg function and its preventive effect of psoriatic arthritis2023
- Author(s)
  Fukasawa Takemichi、Yamashita Takashi、Enomoto Atsushi、Norimatsu Yuta、Toyama Satoshi、Yoshizaki-Ogawa Asako、Tateishi Shoko、Kanda Hiroko、Miyagawa Kiyoshi、Sato Shinichi、Yoshizaki Ayumi
- Journal Title
  
  Frontiers in Immunology
  
  Volume: 14 Pages: 1286251-1286251
- DOI
  10.3389/fimmu.2023.1286251
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K16258, KAKENHI-PROJECT-23K07055, KAKENHI-PROJECT-22K20747
[Journal Article] The Autoantibody Array Assay: A Novel Autoantibody Detection Method2023
- Author(s)
  Norimatsu Yuta、Matsuda Kazuki Mitsuru、Yamaguchi Kei、Ono Chihiro、Okumura Taishi、Kogo Emi、Kotani Hirohito、Hisamoto Teruyoshi、Kuzumi Ai、Fukasawa Takemichi、Yoshizaki-Ogawa Asako、Goshima Naoki、Sato Shinichi、Yoshizaki Ayumi
- Journal Title
  
  Diagnostics
  
  Volume: 13 Issue: 18 Pages: 2929-2929
- DOI
  10.3390/diagnostics13182929
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K16258, KAKENHI-PROJECT-22K08425, KAKENHI-PROJECT-21H02939
[Journal Article] Long-term outcomes after rituximab treatment for patients with systemic sclerosis: follow-up of the DESIRES trial with a focus on serum immunoglobulin levels2023
- Author(s)
  Kuzumi A, Ebata S, Fukasawa T, Matsuda KM, Kotani H, Yoshizaki-Ogawa A, Sato S, Yoshizaki A
- Journal Title
  
  JAMA Dermatol
  
  Volume: - Issue: 4 Pages: 374-374
- DOI
  10.1001/jamadermatol.2022.6340
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K16259, KAKENHI-PROJECT-21H02939, KAKENHI-PROJECT-22K16258
[Journal Article] Impact of guselkumab on three cases of SSc accompanying psoriasis2023
- Author(s)
  Fukasawa Takemichi、Yoshizaki-Ogawa Asako、Yoshizaki Ayumi、Sato Shinichi
- Journal Title
  
  Rheumatology
  
  Volume: 63 Issue: 1 Pages: e6-e8
- DOI
  10.1093/rheumatology/kead287
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K16258
[Journal Article] Comprehensive autoantibody profiling in systemic autoimmunity by a highly-sensitive multiplex protein array2023
- Author(s)
  Kuzumi Ai、Norimatsu Yuta、Matsuda Kazuki M.、Ono Chihiro、Okumura Taishi、Kogo Emi、Goshima Naoki、Fukasawa Takemichi、Fushida Natsumi、Horii Motoki、Yamashita Takashi、Yoshizaki-Ogawa Asako、Yamaguchi Kei、Matsushita Takashi、Sato Shinichi、Yoshizaki Ayumi
- Journal Title
  
  Frontiers in Immunology
  
  Volume: 14 Pages: 1255540-1255540
- DOI
  10.3389/fimmu.2023.1255540
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K16258, KAKENHI-PROJECT-22K16259, KAKENHI-PROJECT-22K08425, KAKENHI-PROJECT-21H02939
[Journal Article] Utility of nailfold capillary assessment for predicting pustulotic arthro-osteitis in palmoplantar pustulosis based on a prospective cohort study2023
- Author(s)
  Fukasawa Takemichi、Yamashita Takashi、Enomoto Atsushi、Toyama Satoshi、Yoshizaki-Ogawa Asako、Tateishi Shoko、Kanda Hiroko、Miyagawa Kiyoshi、Sato Shinichi、Yoshizaki Ayumi
- Journal Title
  
  Journal of the American Academy of Dermatology
  
  Volume: 89 Issue: 5 Pages: 984-991
- DOI
  10.1016/j.jaad.2023.07.1014
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K16258, KAKENHI-PROJECT-23K07055, KAKENHI-PROJECT-21H02939
[Journal Article] Optimal treatments and outcome measures of palmoplantar pustulosis: A systematic review and network meta‐analysis‐based comparison of treatment efficacy2023
- Author(s)
  Fukasawa Takemichi、Yamashita Takashi、Enomoto Atsushi、Yoshizaki‐Ogawa Asako、Miyagawa Kiyoshi、Sato Shinichi、Yoshizaki Ayumi
- Journal Title
  
  Journal of the European Academy of Dermatology and Venereology
  
  Volume: 38 Issue: 2 Pages: 281-288
- DOI
  10.1111/jdv.19499
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K16258
[Journal Article] Safety and efficacy of rituximab in systemic sclerosis (DESIRES): open-label extension of a double-blind, investigators-initiated, randomised, placebo-controlled trial2022
- Author(s)
  Ebata Satoshi、Yoshizaki Ayumi、Oba Koji、Kashiwabara Kosuke、Ueda Keiko、Uemura Yukari、Watadani Takeyuki、Fukasawa Takemichi、Miura Shunsuke、Yoshizaki-Ogawa Asako、Okiyama Naoko、Kodera Masanari、Hasegawa Minoru、Sato Shinichi
- Journal Title
  
  The Lancet Rheumatology
  
  Volume: 4 Issue: 8 Pages: e546-e555
- DOI
  10.1016/s2665-9913(22)00131-x
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22K16258
[Journal Article] Predictors of rituximab effect on modified Rodnan skin score in systemic sclerosis: a machine-learning analysis of the DesiReS trial2022
- Author(s)
  Ebata Satoshi、Oba Koji、Kashiwabara Kosuke、Ueda Keiko、Uemura Yukari、Watadani Takeyuki、Fukasawa Takemichi、Miura Shunsuke、Yoshizaki-Ogawa Asako、Yoshihide Asano、Yoshizaki Ayumi、Sato Shinichi
- Journal Title
  
  Rheumatology
  
  Volume: 5 Issue: 11 Pages: 5-5
- DOI
  10.1093/rheumatology/keac023
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20K22925, KAKENHI-PROJECT-22K16258
[Journal Article] Decrease in MAP3Ks expression enhances the cell death caused by hyperthermia2022
- Author(s)
  Enomoto Atsushi、Fukasawa Takemichi、Terunuma Hiroshi、Nakagawa Keiichi、Yoshizaki Ayumi、Sato Shinichi、Miyagawa Kiyoshi
- Journal Title
  
  International Journal of Hyperthermia
  
  Volume: 39 Issue: 1 Pages: 200-208
- DOI
  10.1080/02656736.2021.2024281
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K22925, KAKENHI-PROJECT-20K08100, KAKENHI-PROJECT-22K16258
[Journal Article] Involvement of B cells in the development of systemic sclerosis2022
- Author(s)
  Yoshizaki A, et al.
- Journal Title
  
  Frontiers in Immunology
  
  Volume: 13
- DOI
  10.3389/fimmu.2022.938785
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K08425, KAKENHI-PROJECT-22K16258, KAKENHI-PROJECT-21K19472
[Journal Article] Autoantibody Landscape Revealed by Wet Protein Array: Sum of Autoantibody Levels Reflects Disease Status2022
- Author(s)
  Matsuda Kazuki M.、Yoshizaki Ayumi、Yamaguchi Kei、Fukuda Eriko、Okumura Taishi、Ogawa Koji、Ono Chihiro、Norimatsu Yuta、Kotani Hirohito、Hisamoto Teruyoshi、Kawanabe Ruriko、Kuzumi Ai、Fukasawa Takemichi、Ebata Satoshi、Miyagawa Takuya、Yoshizaki-Ogawa Asako、Goshima Naoki、Sato Shinichi
- Journal Title
  
  Frontiers in Immunology
  
  Volume: 13 Pages: 893086-893086
- DOI
  10.3389/fimmu.2022.893086
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K16258, KAKENHI-PROJECT-22K16259, KAKENHI-PROJECT-21K19472
[Journal Article] Involvement of Molecular Mechanisms between T/B Cells and IL-23: From Palmoplantar Pustulosis to Autoimmune Diseases2022
- Author(s)
  Fukasawa T, Yoshizaki-Ogawa A, Yoshizaki A.
- Journal Title
  
  International Journal of Molecular Sciences
  
  Volume: 23 Issue: 15 Pages: 8261-8261
- DOI
  10.3390/ijms23158261
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K08425, KAKENHI-PROJECT-22K16258
[Journal Article] AN APPLICATION FOR SUPPORTING CT INTERPRETATION OF INTERSTITIAL PNEUMONIA2022
- Author(s)
  吉田純司、朱奕綸、吉崎歩、深澤毅倫、阿部雅人
- Journal Title
  
  Intelligence, Informatics and Infrastructure
  
  Volume: 3 Issue: J2 Pages: 346-352
- DOI
  10.11532/jsceiii.3.J2_346
- ISSN
  2435-9262
- Language
  Japanese
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K16258
[Journal Article] Utility of nailfold capillary assessment for predicting psoriatic arthritis based on a prospective observational cohort study2022
- Author(s)
  Fukasawa Takemichi、Toyama Satoshi、Enomoto Atsushi、Yoshizaki-Ogawa Asako、Norimatsu Yuta、Tateishi Shoko、Kanda Hiroko、Miyagawa Kiyoshi、Sato Shinichi、Yoshizaki Ayumi
- Journal Title
  
  Rheumatology
  
  Volume: - Issue: 7 Pages: 2418-2425
- DOI
  10.1093/rheumatology/keac664
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22K16258, KAKENHI-PROJECT-22K20747
[Journal Article] Pharmacotherapy of Itch-Antihistamines and Histamine Receptors as G Protein-Coupled Receptors2022
- Author(s)
  Fukasawa Takemichi、Yoshizaki-Ogawa Asako、Enomoto Atsushi、Miyagawa Kiyoshi、Sato Shinichi、Yoshizaki Ayumi
- Journal Title
  
  International Journal of Molecular Sciences
  
  Volume: 23 Issue: 12 Pages: 6579-6579
- DOI
  10.3390/ijms23126579
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K16258
[Journal Article] Serum C-X-C Chemokine Ligand 1 Levels in Patients with Systemic Sclerosis: Relationship of Clinical and Laboratory Observations to Anti-CD20 Monoclonal Antibody Administration2022
- Author(s)
  Kawanabe R, Yoshizaki A, et al
- Journal Title
  
  Life
  
  Volume: 12 Issue: 5 Pages: 646-646
- DOI
  10.3390/life12050646
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K08425, KAKENHI-PROJECT-22K16258, KAKENHI-PROJECT-22K16259
[Journal Article] Clinical Significance of Anti-U1 Ribonucleoprotein Antibody in Anti-Topoisomerase I Antibody-Positive Systemic Sclerosis Patients: A Retrospective Observational Study2021
- Author(s)
  Kazuki M Matsuda, Ayumi Yoshizaki, Hirohito Kotani, Ai Kuzumi, Maiko Fukayama, Takemichi Fukasawa, Satoshi Ebata, Asako Yoshizaki-Ogawa, Yoshihide Asano, Koji Oba, Shinichi Sato
- Journal Title
  
  Archives of Clinical and Biomedical Research
  
  Volume: 5 Pages: 76-84
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K22925
[Journal Article] Single-cell-level protein analysis revealing the roles of autoantigen-reactive B lymphocytes in autoimmune disease and the murine model.2021
- Author(s)
  Fukasawa T, Yoshizaki A, Ebata S, Yoshizaki-Ogawa A, Asano Y, Enomoto A, Miyagawa K, Kazoe Y, Mawatari K, Kitamori T, Sato S.
- Journal Title
  
  Elife
  
  Volume: 10 Pages: 5-5
- DOI
  10.7554/elife.67209
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K08787, KAKENHI-PROJECT-20K22925, KAKENHI-PROJECT-20K08100
[Journal Article] Interleukin-31 promotes fibrosis and T helper 2 polarization in systemic sclerosis2021
- Author(s)
  Kuzumi Ai、Yoshizaki Ayumi、Matsuda Kazuki M.、Kotani Hirohito、Norimatsu Yuta、Fukayama Maiko、Ebata Satoshi、Fukasawa Takemichi、Yoshizaki-Ogawa Asako、Asano Yoshihide、Morikawa Kyojiro、Kazoe Yutaka、Mawatari Kazuma、Kitamori Takehiko、Sato Shinichi
- Journal Title
  
  Nature Communications
  
  Volume: 12 Issue: 1 Pages: 5-5
- DOI
  10.1038/s41467-021-26099-w
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K22925, KAKENHI-PROJECT-21H02939
[Journal Article] Cutaneous Sarcoidosis as a Predictor of Cardiac Sarcoidosis2021
- Author(s)
  Yuta Norimatsu, Ayumi Yoshizaki, Yuki Ohno, Yuka Mizuno, Haruka Watanabe, Hirohito Kotani, Kazuki M Matsuda, Maiko Fukayama, Ai Kuzumi, Satoshi Ebata, Takemichi Fukasawa, Asako Yoshizaki-Ogawa, Shinichi Sato
- Journal Title
  
  Archives of Clinical and Biomedical Research
  
  Volume: 5 Pages: 368-375
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K22925
[Journal Article] Development of a prediction model of treatment response in patients with cutaneous arteritis: Insights from a cohort of 33 patients2021
- Author(s)
  Matsuda Kazuki Mitsuru、Yoshizaki Ayumi、Kotani Hirohito、Kuzumi Ai、Fukayama Maiko、Ebata Satoshi、Fukasawa Takemichi、Yoshizaki‐Ogawa Asako、Sato Shinichi
- Journal Title
  
  The Journal of Dermatology
  
  Volume: 5 Issue: 7 Pages: 5-5
- DOI
  10.1111/1346-8138.15868
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20K22925
[Journal Article] Expert-Level Distinction of Systemic Sclerosis from Hand Photographs Using Deep Convolutional Neural Networks2021
- Author(s)
  Norimatsu Yuta、Yoshizaki Ayumi、Kabeya Yoshinori、Fukasawa Takemichi、Omatsu Jun、Fukayama Maiko、Kuzumi Ai、Ebata Satoshi、Yoshizaki-Ogawa Asako、Asano Yoshihide、Ichimura Haruka、Yonezawa Sho、Nakano Hiroki、Sato Shinichi
- Journal Title
  
  Journal of Investigative Dermatology
  
  Volume: 141 Issue: 10 Pages: 2536-2539
- DOI
  10.1016/j.jid.2021.03.020
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K22925
[Journal Article] Increased Red Blood Cell Distribution Width in the First Year after Diagnosis Predicts Worsening of Systemic Sclerosis-Associated Interstitial Lung Disease at 5 Years: A Pilot Study2021
- Author(s)
  Ebata Satoshi、Yoshizaki Ayumi、Fukasawa Takemichi、Yoshizaki-Ogawa Asako、Asano Yoshihide、Kashiwabara Kosuke、Oba Koji、Sato Shinichi
- Journal Title
  
  Diagnostics
  
  Volume: 11 Issue: 12 Pages: 2274-2274
- DOI
  10.3390/diagnostics11122274
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K22925
[Journal Article] Serum heat shock protein 27 levels in patients with systemic sclerosis: a possible biomarker of skin sclerosis2021
- Author(s)
  Matsuda K.M.、Yoshizaki A.、Kotani H.、Norimatsu Y.、Kuzumi A.、Fukayama M.、Fukasawa T.、Ebata S.、Yoshizaki‐Ogawa A.、Asano Y.、Oba K.、Sato S.
- Journal Title
  
  Journal of the European Academy of Dermatology and Venereology
  
  Volume: 35 Issue: 2 Pages: 250-250
- DOI
  10.1111/jdv.16885
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20K22925
[Journal Article] Safety and efficacy of rituximab in systemic sclerosis (DESIRES): a double-blind, investigator-initiated, randomised, placebo-controlled trial.2021
- Author(s)
  Ebata, S., Yoshizaki, A., Oba, K., Kashiwabara, K., Ueda, K., Uemura, Y., Watadani, T., Fukasawa, T., Miura, S., Yoshizaki-Ogawa, A., Asano, Y., Okiyama, N., Kodera, M., Hasegawa, M., & Sato, S.
- Journal Title
  
  Lancet Rheumatology
  
  Volume: 3 Pages: 489-497
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20K22925
[Journal Article] COVID-19 pandemic highlighted the importance of telemedicine in the collagen disease of systemic sclerosis2021
- Author(s)
  Y. Norimatsu, A. Yoshizaki, T. Fukasawa, S. Ebata, K. Oba, S. Sato
- Journal Title
  
  Clinical and Experimental Rheumatology
  
  Volume: 39 Pages: 160-160
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K22925
[Journal Article] Serum Calponin 3 Levels in Patients with Systemic Sclerosis: Possible Association with Skin Sclerosis and Arthralgia2021
- Author(s)
  Kotani Hirohito、Yoshizaki Ayumi、Matsuda Kazuki M.、Norimatsu Yuta、Kuzumi Ai、Fukayama Maiko、Fukasawa Takemichi、Ebata Satoshi、Yoshizaki-Ogawa Asako、Asano Yoshihide、Oba Koji、Sato Shinichi
- Journal Title
  
  Journal of Clinical Medicine
  
  Volume: 10 Issue: 2 Pages: 280-280
- DOI
  10.3390/jcm10020280
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K22925
[Journal Article] Serum TARC Levels in Patients with Systemic Sclerosis: Clinical Association with Interstitial Lung Disease2021
- Author(s)
  Kuzumi Ai、Yoshizaki Ayumi、Ebata Satoshi、Fukasawa Takemichi、Yoshizaki-Ogawa Asako、Asano Yoshihide、Oba Koji、Sato Shinichi
- Journal Title
  
  Journal of Clinical Medicine
  
  Volume: 10 Issue: 4 Pages: 660-660
- DOI
  10.3390/jcm10040660
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K22925
[Journal Article] Rapid decrease of serum surfactant protein‐D levels predicts the reactivity of rituximab therapy in systemic sclerosis‐associated interstitial lung disease2021
- Author(s)
  Ebata Satoshi、Yoshizaki Ayumi、Fukasawa Takemichi、Asano Yoshihide、Oba Koji、Sato Shinichi
- Journal Title
  
  The Journal of Dermatology
  
  Volume: 47 Issue: 7 Pages: 796-800
- DOI
  10.1111/1346-8138.15379
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20K22925
[Journal Article] Percentage of residual B cells after 2 weeks of rituximab treatment predicts the improvement of systemic sclerosis‐associated interstitial lung disease2021
- Author(s)
  Ebata Satoshi、Yoshizaki Ayumi、Fukasawa Takemichi、Yoshizaki‐Ogawa Asako、Asano Yoshihide、Kashiwabara Kosuke、Oba Koji、Sato Shinichi
- Journal Title
  
  The Journal of Dermatology
  
  Volume: 49 Issue: 1 Pages: 179-183
- DOI
  10.1111/1346-8138.16206
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20K22925, KAKENHI-PROJECT-21K19473, KAKENHI-PROJECT-23K24354
[Journal Article] Interleukin (IL)‐17F and IL‐17E are related to fibrosis and vasculopathy in systemic sclerosis2021
- Author(s)
  Fukayama Maiko、Yoshizaki Ayumi、Fukasawa Takemichi、Ebata Satoshi、Kuzumi Ai、Yoshizaki‐Ogawa Asako、Asano Yoshihide、Oba Koji、Sato Shinichi
- Journal Title
  
  The Journal of Dermatology
  
  Volume: 47 Issue: 11 Pages: 1287-1292
- DOI
  10.1111/1346-8138.15508
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20K22925
[Journal Article] B Cell Depletion Inhibits Fibrosis via Suppression of Profibrotic Macrophage Differentiation in a Mouse Model of Systemic Sclerosis2021
- Author(s)
  Numajiri Hiroko、Kuzumi Ai、Fukasawa Takemichi、Ebata Satoshi、Yoshizaki‐Ogawa Asako、Asano Yoshihide、Kazoe Yutaka、Mawatari Kazuma、Kitamori Takehiko、Yoshizaki Ayumi、Sato Shinichi
- Journal Title
  
  Arthritis & Rheumatology
  
  Volume: 73 Issue: 11 Pages: 2086-2095
- DOI
  10.1002/art.41798
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20K22925
[Presentation] Single cell protein analysis of autoantigen-reactive B cells in the autoimmune disease and the murine model2022
- Author(s)
  Takemichi Fukasawa, Satoshi Ebata, Asako Yoshizaki, Shinichi Sato, and Ayumi Yoshizaki
- Organizer
  47th JSID
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K16258
[Presentation] EFFICACY AND SAFETY OF SUBCUTANEOUS BRODALUMAB, A FULLY HUMAN ANTI-IL-17RA MONOCLONAL ANTIBODY, FOR SYSTEMIC SCLEROSIS WITH MODERATE-TO-SEVERE SKIN THICKENING: A MULTICENTER, RANDOMIZED, PLACEBO-CONTROLLED, DOUBLE-BLIND PHASE 3 STUDY.2022
- Author(s)
  T Fukasawa, et al.
- Organizer
  EULAR
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K16258
[Presentation] Role of IL-17 and IL-17 receptors in various cells and diseases2022
- Author(s)
  Takemichi Fukasawa, Ayumi Yoshizaki, Shinichi Sato
- Organizer
  47th JSID
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K16258
[Presentation] PHARMACOKINETICS, SAFETY, AND EFFICACY OF SUBCUTANEOUS BRODALUMAB FOR SYSTEMIC SCLEROSIS WITH MODERATE-TO-SEVERE SKIN THICKENING: A SINGLE-ARM, OPEN-LABEL, MULTI-DOSE, PHASE 1 TRIAL.2022
- Author(s)
  T Fukasawa, et al.
- Organizer
  EULAR
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K16258
[Presentation] 様々な細胞や疾患におけるIL-17とIL-17受容体の役割2022
- Author(s)
  深澤　毅倫、吉崎　歩、佐藤　伸一
- Organizer
  第73回日本皮膚科学会中部支部学術大会
- Data Source
  KAKENHI-PROJECT-22K16258
[Presentation] Single cell level protein analysis of autoantigen-reactive B cells in systemic sclerosis and the murine model.2022
- Author(s)
  T Fukasawa, et al.
- Organizer
  ESDR
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K16258
[Presentation] 全身性強皮症およびモデルマウスにおける自己抗原反応性B細胞の単一細胞解析2022
- Author(s)
  深澤　毅倫、吉崎　歩、佐藤　伸一
- Organizer
  第50回日本臨床免疫学会総会
- Data Source
  KAKENHI-PROJECT-22K16258
[Presentation] 様々な細胞や疾患におけるIL-17とIL-17受容体の役割2022
- Author(s)
  深澤　毅倫、吉崎　歩、佐藤　伸一
- Organizer
  第50回日本臨床免疫学会総会
- Data Source
  KAKENHI-PROJECT-22K16258
[Presentation] Safety and Efficacy of Rituximab for Systemic Sclerosis: A Double-Blind, Parallel-Group Comparison, Investigators Initiated Confirmatory Randomized Clinical Trial (DESIRES Study)2021
- Author(s)
  Satoshi Ebata, Ayumi Yoshizaki, Koji Oba, Kosuke Kashiwabara, Keiko Ueda, Yukari Umemura, Takeyuki Watadani, Takemichi Fukasawa, Shunsuke Miura, Asako Yoshizaki-Ogawa, Yoshihide Asano, Naoko Okiyama, Masanari Kodera, Minoru Hasegawa and Shinichi Sato
- Organizer
  American college of rheumatology 2021
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K22925

1. YOSHIZAKI Ayumu

# of Collaborated Projects: 0 results

# of Collaborated Products: 5 results
2. 榎本敦

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
3. 久住藍

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Fukasawa Takemichi 深澤 毅倫

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Single-cell analysis of autoantigen-reactive B cells in systemic sclerosis and development of novel therapeutic targetsPrincipal Investigator

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Analysis of the effect of cytokine production by autoantigen-reactive B cells in systemic sclerosis on other immune systems.Principal Investigator

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[Book] 「臨床と研究」2022

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[Book] 皮膚科 膠原病 皮疹から全身を診る2021

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[Journal Article] Deregulated JNK signaling enhances apoptosis during hyperthermia2024

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[Journal Article] Cannabinoids for the treatment of autoimmune and inflammatory skin diseases: A systematic review2024

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[Journal Article] Dual blockade of interleukin-17A and interleukin-17F as a therapeutic strategy for liver fibrosis: Investigating the potential effect and mechanism of brodalumab2024

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[Journal Article] Reliability, validity, and sensitivity of the Japanese version of the University of California Los Angeles scleroderma clinical trial consortium gastrointestinal tract instrument: Application to efficacy assessment of intravenous immunoglobulin administration2024

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[Journal Article] Autoantibodies to nuclear valosin-containing protein-like protein: systemic sclerosis-specific antibodies revealed by in vitro human proteome2024

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[Journal Article] The role of B cells in systemic sclerosis2024

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[Journal Article] Significance of anti-transcobalamin receptor antibodies in cutaneous arteritis revealed by proteome-wide autoantibody screening2023

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[Journal Article] The role of STK38 in DNA damage response and targeting for radio-sensitization.2023

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[Journal Article] Interleukin-17 pathway inhibition with brodalumab in early systemic sclerosis: analysis of a single-arm, open-label, phase 1 trial2023

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[Journal Article] The optimal use of tildrakizumab in the elderly via improvement of Treg function and its preventive effect of psoriatic arthritis2023

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[Journal Article] The Autoantibody Array Assay: A Novel Autoantibody Detection Method2023

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Fukasawa Takemichi 深澤毅倫

[Book] 皮膚科　膠原病　皮疹から全身を診る2021