Hongo Hiroki 本郷博貴

Researcher Number	80908682
Affiliation (Current)	2025: 東京大学, 医学部附属病院, 助教
Affiliation (based on the past Project Information) *help	2021 – 2024: 東京大学, 医学部附属病院, 助教
Review Section/Research Field	Principal Investigator Basic Section 56010:Neurosurgery-related / 0906:Surgery related to the biological and sensory functions and related fields Except Principal Investigator Basic Section 56010:Neurosurgery-related
Keywords	Principal Investigator モデル動物 / 脳海綿状血管奇形 / 血管奇形 / 遺伝子変異 / 細胞実験 / 脳血管奇形 / 個別化治療 / 動物モデル Except Principal Investigator long read sequencing / RNF213 … More / もやもや病 / タンパク質構造解析 / 分子標的治療 / モデル動物 / 血管内皮細胞 / 血管奇形 Less

Molecular mechanisms underlying acute hemorrhage in cerebral cavernous malformationsPrincipal Investigator
- Principal Investigator
  
  本郷博貴
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 56010:Neurosurgery-related
- Research Institution
  The University of Tokyo
Elucidation of genetic factors of moyamoya disease and search for therapeutic targets using long read sequencing
- Principal Investigator
  
  宮脇哲
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 56010:Neurosurgery-related
- Research Institution
  The University of Tokyo
Novel animal model of cerebrovascular malformationsPrincipal Investigator
- Principal Investigator
  
  Hongo Hiroki
- Project Period (FY)
  2022 – 2023
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 56010:Neurosurgery-related
- Research Institution
  The University of Tokyo
Analysis of the pathogenesis of cerebral cavernous malformations using patient-derived xenograftsPrincipal Investigator
- Principal Investigator
  
  Hongo Hiroki
- Project Period (FY)
  2021 – 2022
- Research Category
  
  Grant-in-Aid for Research Activity Start-up
- Review Section
  
  0906:Surgery related to the biological and sensory functions and related fields
- Research Institution
  The University of Tokyo
Analysis of novel vascular malformation causative gene
- Principal Investigator
  
  齊藤延人
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 56010:Neurosurgery-related
- Research Institution
  The University of Tokyo

All 2023 2022 2021 Other

All Journal Article Presentation Other

[Journal Article] Hypertensive disorders of pregnancy in moyamoya disease: A single institution experience2023
- Author(s)
  Yajima Hirohisa、Miyawaki Satoru、Sayama Seisuke、Kumasawa Keiichi、Ikemura Masako、Imai Hideaki、Hongo Hiroki、Hirano Yudai、Ishigami Daiichiro、Torazawa Seiei、Kiyofuji Satoshi、Koizumi Satoshi、Saito Nobuhito
- Journal Title
  
  Journal of Stroke and Cerebrovascular Diseases
  
  Volume: 32 Issue: 11 Pages: 107377-107377
- DOI
  10.1016/j.jstrokecerebrovasdis.2023.107377
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22K16677
[Journal Article] Cerebrovascular Events During Treatment for Systemic Malignant Tumors in Patients with Moyamoya Disease2023
- Author(s)
  Ogawa Shotaro、Miyawaki Satoru、Imai Hideaki、Hongo Hiroki、Umekawa Motoyuki、Kiyofuji Satoshi、Ishigami Daiichiro、Sakai Yu、Torazawa Seiei、Hirano Yudai、Koizumi Satoshi、Saito Nobuhito
- Journal Title
  
  World Neurosurgery
  
  Volume: 179 Pages: e314-e320
- DOI
  10.1016/j.wneu.2023.08.083
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22K16677
[Journal Article] Clinical and Genetic Characteristics of Patients with Moyamoya Disease who Experienced Both Ischemic and Hemorrhagic Events2023
- Author(s)
  Hirano Yudai、Miyawaki Satoru、Imai Hideaki、Hongo Hiroki、Teranishi Yu、Ishigami Daiichiro、Sakai Yu、Shimada Daisuke、Umekawa Motoyuki、Segawa Masafumi、Koizumi Satoshi、Ono Hideaki、Nakatomi Hirofumi、Saito Nobuhito
- Journal Title
  
  World Neurosurgery
  
  Volume: 172 Pages: e438-e446
- DOI
  10.1016/j.wneu.2023.01.047
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22K16677
[Journal Article] Bypass Surgery for Adult-Onset Hemorrhagic Moyamoya Disease: Analysis Classified by Site of Initial Bleeding2023
- Author(s)
  Hirano Yudai、Miyawaki Satoru、Imai Hideaki、Hongo Hiroki、Koizumi Satoshi、Yajima Hirohisa、Torazawa Seiei、Ishigami Daiichiro、Kiyofuji Satoshi、Saito Nobuhito
- Journal Title
  
  World Neurosurgery
  
  Volume: 178 Pages: e585-e594
- DOI
  10.1016/j.wneu.2023.07.130
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22K16677
[Journal Article] Genome-Wide Association Study of Intracranial Artery Stenosis Followed by Phenome-Wide Association Study2022
- Author(s)
  Dofuku S, Sonehara K, Miyawaki S, Sakaue S, Imai H, Shimizu M, Hongo H, Shinya Y, Ohara K, Teranishi Y, Okano A, Ono H, Nakatomi H, Teraoka A, Yamamoto K, Maeda Y, Nii T, Kishikawa T, Suzuki K, Hirata J, Takahashi M, Matsuda K, Kumanogoh A, Matsuda F, Okada Y, Saito N.
- Journal Title
  
  Transl Stroke Res.
  
  Volume: - Issue: 3 Pages: 322-333
- DOI
  10.1007/s12975-022-01049-w
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K09473, KAKENHI-PROJECT-22K16677
[Journal Article] NF2 Alteration/22q Loss Is Associated with Recurrence in WHO Grade 1 Sphenoid Wing Meningiomas2022
- Author(s)
  Sakai Y, Miyawaki S, Teranishi Y, Okano A, Ohara K, Hongo H, Ishigami D, Shimada D, Mitsui J, Nakatomi H, Saito N.
- Journal Title
  
  Cancers (Basel)
  
  Volume: 14(13):3183 Issue: 13 Pages: 3183-3183
- DOI
  10.3390/cancers14133183
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K09473, KAKENHI-PROJECT-21H03041
[Journal Article] Genetics of brain arteriovenous malformations and cerebral cavernous malformations2022
- Author(s)
  Hongo Hiroki、Miyawaki Satoru、Teranishi Yu、Ishigami Daiichiro、Ohara Kenta、Sakai Yu、Shimada Daisuke、Umekawa Motoyuki、Koizumi Satoshi、Ono Hideaki、Nakatomi Hirofumi、Saito Nobuhito
- Journal Title
  
  Journal of Human Genetics
  
  Volume: 68 Issue: 3 Pages: 157-167
- DOI
  10.1038/s10038-022-01063-8
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K16677, KAKENHI-PROJECT-19K09473, KAKENHI-PROJECT-21K20985
[Journal Article] Symptomatic and Stenotic Developmental Venous Anomaly with Pontine Capillary Telangiectasia: A Case Report with Genetic Considerations2022
- Author(s)
  ISHIGAMI Daiichiro、KOIZUMI Satoshi、MIYAWAKI Satoru、HONGO Hiroki、TERANISHI Yu、MITSUI Jun、SAITO Nobuhito
- Journal Title
  
  NMC Case Report Journal
  
  Volume: 9 Issue: 0 Pages: 139-144
- DOI
  10.2176/jns-nmc.2022-0022
- ISSN
  2188-4226
- Year and Date
  2022-12-31
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K16677, KAKENHI-PROJECT-19K09473, KAKENHI-PROJECT-21K20985
[Journal Article] Early prediction of functional prognosis in neurofibromatosis type 2 patients based on genotype-phenotype correlation with targeted deep sequencing2022
- Author(s)
  Yu Teranishi、Satoru Miyawaki、Hirofumi Nakatomi、Kenta Ohara、Hiroki Hongo、Shogo Dofuku、Atsushi Okano、Shunsaku Takayanagi、Takahiro Ota、Jun Yoshimura、Wei Qu、Jun Mitsui、Shinichi Morishita、Shoji Tsuji、Nobuhito Saito
- Journal Title
  
  Scientific Reports
  
  Volume: 12(1) Issue: 1 Pages: 9543-9543
- DOI
  10.1038/s41598-022-13580-9
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22H04925, KAKENHI-PROJECT-19K09473, KAKENHI-PROJECT-21H03041
[Journal Article] Differences in Clinical Features among Different Onset Patterns in Moyamoya Disease.2021
- Author(s)
  Hirano Y, Miyawaki S, Imai H, Hongo H, Teranishi Y, Dofuku S, Ishigami D, Ohara K, Koizumi S, Ono H, Nakatomi H, Saito N.
- Journal Title
  
  J Clin Med.
  
  Volume: 10(13) Issue: 13 Pages: 2815-2815
- DOI
  10.3390/jcm10132815
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21H03041
[Journal Article] RNF213 p.Arg4810Lys Heterozygosity in Moyamoya Disease Indicates Early Onset and Bilateral Cerebrovascular Events.2021
- Author(s)
  Ishigami D, Miyawaki S, Imai H, Shimizu M, Hongo H, Dofuku S, Ohara K, Teranishi Y, Shimada D, Koizumi S, Ono H, Hirano Y, Segawa M, Nakatomi H, Saito N.
- Journal Title
  
  Transl Stroke Res.
  
  Volume: 13(3) Issue: 3 Pages: 410-419
- DOI
  10.1007/s12975-021-00956-8
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K09473, KAKENHI-PROJECT-21H03041
[Presentation] 脳および眼窩内海綿状血管奇形の体細胞遺伝子変異解析2023
- Author(s)
  本郷博貴, 宮脇哲, 寺西裕, 堂福翔吾, 小原健太, 石神大一郎, 岡野淳, 三井純, 加藤洋人, 栗田昌和, 渡邉正勝, 辛正廣, 中冨浩文, 後藤浩, 石川俊平, 齊藤延人.
- Organizer
  第52回日本脳卒中の外科学会
- Data Source
  KAKENHI-PROJECT-22K16677
[Presentation] 多発性脳海綿状血管奇形に対する生殖細胞系列遺伝子解析.2023
- Author(s)
  本郷博貴, 宮脇哲, 寺西裕, 石神大一郎, 小原健太, 酒井優, 齊藤延人.
- Organizer
  第47回日本脳卒中学会学術集会
- Data Source
  KAKENHI-PROJECT-21H03041
[Presentation] 脳・眼窩内血管奇形の遺伝子解析研究2023
- Author(s)
  本郷博貴, 宮脇哲, 寺西裕, 堂福翔吾, 小原健太, 石神大一郎, 岡野淳, 清藤哲史, 三井純, 栗田昌和, 渡邉正勝, 辛正廣, 中冨浩文, 後藤浩, 石川俊平, 齊藤延人.
- Organizer
  第81回日本脳神経外科学会総会
- Invited
- Data Source
  KAKENHI-PROJECT-22K16677
[Presentation] Epidemiology/etiology of cerebral cavernous malformations.2022
- Author(s)
  Hiroki Hongo, Satoru Miyawaki, Nobuhito Saito.
- Organizer
  10th European-Japanese Cerebrovascular Congress.
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21H03041
[Presentation] 眼窩内海綿状血管奇形関連遺伝子変異の同定2022
- Author(s)
  本郷博貴, 宮脇哲, 栗田昌和, 加藤基, 寺西裕, 堂福翔吾, 小原健太, 石神大一郎, 岡野淳, 三井純, 加藤洋人, 渡邉正勝, 辛正廣, 中冨浩文, 後藤浩, 石川俊平, 岡崎睦, 齊藤延人
- Organizer
  第18回日本血管腫血管奇形学会学術集会
- Data Source
  KAKENHI-PROJECT-21K20985
[Presentation] 眼窩内海綿状血管奇形における新規関連遺伝子変異の同定2022
- Author(s)
  本郷博貴, 宮脇哲, 寺西裕, 堂福翔吾, 小原健太, 石神大一郎, 岡野淳, 三井純, 加藤洋人, 栗田昌和, 渡邉正勝, 辛正廣, 中冨浩文, 後藤浩, 石川俊平, 齊藤延人
- Organizer
  日本脳神経外科学会第81回学術総会
- Data Source
  KAKENHI-PROJECT-21K20985
[Presentation] 眼窩内海綿状血管奇形関連遺伝子変異の同定.2022
- Author(s)
  本郷博貴, 宮脇哲, 栗田昌和, 加藤基, 寺西裕, 堂福翔吾, 小原健太, 石神大一郎, 岡野淳, 三井純, 加藤洋人, 渡邉正勝, 辛正廣, 中冨浩文, 後藤浩, 石川俊平, 岡崎睦, 齊藤延人.
- Organizer
  第18回日本血管腫血管奇形学会学術集会
- Data Source
  KAKENHI-PROJECT-21H03041
[Presentation] 眼窩内海綿状血管奇形における新規関連遺伝子変異の同定2022
- Author(s)
  本郷博貴, 宮脇哲, 寺西裕, 堂福翔吾, 小原健太, 石神大一郎, 岡野淳, 三井純, 加藤洋人, 栗田昌和, 渡邉正勝, 辛正廣, 中冨浩文, 後藤浩, 石川俊平, 齊藤延人
- Organizer
  日本脳神経外科学会第81回学術総会
- Data Source
  KAKENHI-PROJECT-22K16677
[Presentation] 眼窩内海綿状血管奇形関連遺伝子変異の同定2022
- Author(s)
  本郷博貴, 宮脇哲, 栗田昌和, 加藤基, 寺西裕, 堂福翔吾, 小原健太, 石神大一郎, 岡野淳, 三井純, 加藤洋人, 渡邉正勝, 辛正廣, 中冨浩文, 後藤浩, 石川俊平, 岡崎睦, 齊藤延人
- Organizer
  第18回日本血管腫血管奇形学会学術集会
- Data Source
  KAKENHI-PROJECT-22K16677
[Presentation] 眼窩内海綿状血管奇形における新規関連遺伝子変異の同定.2022
- Author(s)
  本郷博貴, 宮脇哲, 寺西裕, 堂福翔吾, 小原健太, 石神大一郎, 岡野淳, 三井純, 加藤洋人, 栗田昌和, 渡邉正勝, 辛正廣, 中冨浩文, 後藤浩, 石川俊平, 齊藤延人.
- Organizer
  日本脳神経外科学会第81回学術総会
- Data Source
  KAKENHI-PROJECT-21H03041
[Presentation] 多発性脳海綿状血管奇形に対する生殖細胞系列遺伝子解析（一般口演）2022
- Author(s)
  本郷博貴, 宮脇哲, 寺西裕, 石神大一郎, 小原健太, 酒井優, 斉藤延人.
- Organizer
  第47回日本脳卒中学会学術集会　大阪国際会議場（ハイブリッド開催）
- Data Source
  KAKENHI-PROJECT-21H03041
[Presentation] Epidemiology/etiology of cerebral cavernous malformations2022
- Author(s)
  Hiroki Hongo, Satoru Miyawaki, Nobuhito Saito
- Organizer
  10th European-Japanese Cerebrovascular Congress
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K20985
[Presentation] Epidemiology/etiology of cerebral cavernous malformations2022
- Author(s)
  Hiroki Hongo, Satoru Miyawaki, Nobuhito Saito
- Organizer
  10th European-Japanese Cerebrovascular Congress
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K16677
[Presentation] 脳海綿状血管奇形のgermline mutationとcopy number variationの解析（シンポジウム）2021
- Author(s)
  本郷博貴, 宮脇哲, 寺西裕, 石神大一郎, 小原健太, 酒井優, 斉藤延人.
- Organizer
  第80回日本脳神経外科学会総会　パシフィコ横浜（WEB併催）
- Data Source
  KAKENHI-PROJECT-21H03041
[Presentation] 脳海綿状血管奇形におけるgermline mutationの解析（一般口演）2021
- Author(s)
  本郷博貴, 宮脇哲, 寺西裕, 石神大一郎, 小原健太, 酒井優, 中冨浩文, 斉藤延人.
- Organizer
  第21回日本分子脳神経外科学会　WEB開催
- Data Source
  KAKENHI-PROJECT-21H03041
[Presentation] 脳海綿状血管奇形におけるgermline mutation解析（一般口演）2021
- Author(s)
  本郷博貴, 宮脇哲, 寺西裕, 石神大一郎, 小原健太, 酒井優, 中冨浩文, 斉藤延人,
- Organizer
  第64回日本脳循環代謝学会学術集会　長良川国際会議場（ハイブリッド開催）
- Data Source
  KAKENHI-PROJECT-21H03041
[]
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1. 齊藤延人 (60262002)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
2. 宮脇哲 (70407914)

# of Collaborated Projects: 3 results

# of Collaborated Products: 12 results
3. 石川俊平 (50418638)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
4. 三井純 (70579862)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
5. 栗田昌和 (20424111)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
6. 寺西裕 (50844635)

# of Collaborated Projects: 1 results

# of Collaborated Products: 8 results
7. 小野秀明 (50771846)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. 岡田随象 (70727411)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. 森下真一 (90292854)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
10. NAKATOMI Hirofumi

# of Collaborated Projects: 0 results

# of Collaborated Products: 3 results
11. ITOH Takehiko

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
12. 斎藤延人

# of Collaborated Projects: 0 results

# of Collaborated Products: 12 results
13. 森宙史

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Hongo Hiroki 本郷 博貴

Research Projects

Research Products

Co-Researchers

Molecular mechanisms underlying acute hemorrhage in cerebral cavernous malformationsPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Elucidation of genetic factors of moyamoya disease and search for therapeutic targets using long read sequencing

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Novel animal model of cerebrovascular malformationsPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Analysis of the pathogenesis of cerebral cavernous malformations using patient-derived xenograftsPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Analysis of novel vascular malformation causative gene

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

[Journal Article] Hypertensive disorders of pregnancy in moyamoya disease: A single institution experience2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Cerebrovascular Events During Treatment for Systemic Malignant Tumors in Patients with Moyamoya Disease2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Clinical and Genetic Characteristics of Patients with Moyamoya Disease who Experienced Both Ischemic and Hemorrhagic Events2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Bypass Surgery for Adult-Onset Hemorrhagic Moyamoya Disease: Analysis Classified by Site of Initial Bleeding2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Genome-Wide Association Study of Intracranial Artery Stenosis Followed by Phenome-Wide Association Study2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] NF2 Alteration/22q Loss Is Associated with Recurrence in WHO Grade 1 Sphenoid Wing Meningiomas2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Genetics of brain arteriovenous malformations and cerebral cavernous malformations2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Symptomatic and Stenotic Developmental Venous Anomaly with Pontine Capillary Telangiectasia: A Case Report with Genetic Considerations2022

Author(s)

Journal Title

DOI

ISSN

Year and Date

Language

Data Source

[Journal Article] Early prediction of functional prognosis in neurofibromatosis type 2 patients based on genotype-phenotype correlation with targeted deep sequencing2022

Author(s)

Journal Title

Hongo Hiroki 本郷博貴