Ono Koya 小野浩弥

Researcher Number	80930445
Other IDs	https://orcid.org/0000-0003-3753-7138
Affiliation (Current)	2024: 東北大学, 大学病院, 非常勤講師
Affiliation (based on the past Project Information) *help	2022 – 2023: 東北大学, 大学病院, 医員 2022: 東北大学, 医学(系)研究科(研究院), その他
Review Section/Research Field	Principal Investigator Basic Section 54010:Hematology and medical oncology-related
Keywords	Principal Investigator フェロトーシス / モデルマウス / 赤血球 / 遺伝性鉄芽球性貧血 / フェロポーチン / フェリチン / ALAS2 / X連鎖性鉄芽球性貧血 / 無効造血 / 悪性リンパ腫 / FSP1

Development of novel therapeutic approach for refractory anemia and malignant lymphoma by targeting ferroptosis suppressor protein-1Principal Investigator
- Principal Investigator
  
  小野浩弥
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Fund for the Promotion of Joint International Research (Fostering Joint International Research (A))
- Review Section
  
  Basic Section 54010:Hematology and medical oncology-related
- Research Institution
  Tohoku University
X連鎖性鉄芽球性貧血における鉄依存性細胞死および鉄代謝制御の解明Principal Investigator
- Principal Investigator
  
  小野浩弥
- Project Period (FY)
  2022 – 2025
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 54010:Hematology and medical oncology-related
- Research Institution
  Tohoku University

All 2022

All Journal Article Presentation

[Journal Article] Congenital sideroblastic anemia model due to ALAS2 mutation is susceptible to ferroptosis2022
- Author(s)
  Ono Koya、Fujiwara Tohru、Saito Kei、Nishizawa Hironari、Takahashi Noriyuki、Suzuki Chie、Ochi Tetsuro、Kato Hiroki、Ishii Yusho、Onodera Koichi、Ichikawa Satoshi、Fukuhara Noriko、Onishi Yasushi、Yokoyama Hisayuki、Yamada Rie、Nakamura Yukio、Igarashi Kazuhiko、Harigae Hideo
- Journal Title
  
  Scientific Reports
  
  Volume: 12 Issue: 1 Pages: 9024-9024
- DOI
  10.1038/s41598-022-12940-9
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K08385, KAKENHI-PROJECT-22K16294, KAKENHI-PROJECT-22H00443, KAKENHI-PROJECT-21K20770
[Journal Article] TM5614, an Inhibitor of Plasminogen Activator Inhibitor-1, Exerts an Antitumor Effect on Chronic Myeloid Leukemia2022
- Author(s)
  Sasaki Katsuyuki、Fujiwara Tohru、Ochi Tetsuro、Ono Koya、Kato Hiroki、Onodera Koichi、Ichikawa Satoshi、Fukuhara Noriko、Onishi Yasushi、Yokoyama Hisayuki、Miyata Toshio、Harigae Hideo
- Journal Title
  
  Tohoku J. Exp. Med.
  
  Volume: 257 Issue: 3 Pages: 211-224
- DOI
  10.1620/tjem.2022.J036
- ISSN
  0040-8727, 1349-3329
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K16294, KAKENHI-PROJECT-21K20770
[Journal Article] T-cell receptor-silent peripheral T-cell lymphoma complicated with hemophagocytic lymphohystiocytosis2022
- Author(s)
  Ono Koya、Onishi Yasushi、Onodera Koichi、Michimata Daigo、Furukawa Eijiro、Sakurai Kazuki、Morota Naoya、Sawada Takumi、Ichikawa Satoshi、Fukuhara Noriko、Yokoyama Hisayuki、Watanabe Hirofumi、Suzuki Chie、Harigae Hideo
- Journal Title
  
  Annals of Hematology
  
  Volume: 101 Issue: 4 Pages: 901-903
- DOI
  10.1007/s00277-021-04628-3
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22K16294
[Journal Article] Elucidation of the Role of FAM210B in Mitochondrial Metabolism and Erythropoiesis2022
- Author(s)
  Suzuki Chie、Fujiwara Tohru、Shima Hiroki、Ono Koya、Saito Kei、Kato Hiroki、Onodera Koichi、Ichikawa Satoshi、Fukuhara Noriko、Onishi Yasushi、Yokoyama Hisayuki、Nakamura Yukio、Igarashi Kazuhiko、Harigae Hideo
- Journal Title
  
  Molecular and Cellular Biology
  
  Volume: 42 Issue: 12
- DOI
  10.1128/mcb.00143-22
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21K08385, KAKENHI-PROJECT-22K16294, KAKENHI-PROJECT-22H00443, KAKENHI-PROJECT-20K07321, KAKENHI-PROJECT-21K20770
[Journal Article] Exploring the mechanistic link between SF3B1 mutation and ring sideroblast formation in myelodysplastic syndrome2022
- Author(s)
  Ochi Tetsuro、Fujiwara Tohru、Ono Koya、Suzuki Chie、Nikaido Maika、Inoue Daichi、Kato Hiroki、Onodera Koichi、Ichikawa Satoshi、Fukuhara Noriko、Onishi Yasushi、Yokoyama Hisayuki、Nakamura Yukio、Harigae Hideo
- Journal Title
  
  Scientific Reports
  
  Volume: 12 Issue: 1 Pages: 14562-14562
- DOI
  10.1038/s41598-022-18921-2
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K08385, KAKENHI-PROJECT-22K16294, KAKENHI-PROJECT-21K20770, KAKENHI-PROJECT-20H03717
[Presentation] Late-onset X-linked sideroblastic anemia due to heterozygous ALAS2 mutation: Insights from two adult female cases2022
- Author(s)
  Koya Ono, Noriko Fukuhara, Minami Yamada-Fujiwara, Tohru Fujiwara, Chie Suzuki, Naoya Morota, Daichi Kiba, Yuya Tanaka, Daigo Michimata, Kyoko Inokura, Koichi Onodera, Satoshi Ichikawa, Yasushi Onishi, Hisayuki Yokoyama, Hideo Harigae
- Organizer
  The 84th Annual Meeting of the Japanese Society of Hematology
- Data Source
  KAKENHI-PROJECT-22K16294
[Presentation] Proteomic changes regulate ferroptosis susceptibility in X-linked sideroblastic anemia2022
- Author(s)
  Koya Ono, Tohru Fujiwa, Chie Suzuki, Noriyuki Takahashi, Hironari Nishizawa, Koichi Onodera, Satoshi Ichikawa, Noriko Fukuhara, Yasushi Onishi, Hisayuki Yokoyama, Yukio Nakamura, Kazuhiko Igarashi, Hideo Harigae
- Organizer
  Cold Spring Harbor Asia meeting on Iron, Reactive Oxygen Species & Ferroptosis in Life, Death & Disease
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K16294
[Presentation] Altered Transcription By GATA1 Impairs Autophagy and Prevents Ferroptosis in X-Linked Sideroblastic Anemia2022
- Author(s)
  Koya Ono, Tohru Fujiwara, Hiroki Shima, Hironari Nishizawa, Chie Suzuki, Noriyuki Takahashi, Hiroki Kato, Koichi Onodera, Satoshi Ichikawa, Noriko Fukuhara, Yasushi Onishi, Hisayuki Yokoyama, Yukio Nakamura, Kazuhiko Igarashi, Hideo Harigae
- Organizer
  63rd American Society of Hematology (ASH) Annual Meeting & Exposition
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K16294
[Presentation] Ferritinophagy is impaired in X-linked sideroblastic anemia models during differentiation2022
- Author(s)
  Koya Ono, Tohru Fujiwara, Chie Suzuki, Noriyuki Takahashi, Koichi Onodera, Satoshi Ichikawa, Noriko Fukuhara, Yasushi Onishi, Hisayuki Yokoyama, Yukio Nakamura, Hideo Harigae
- Organizer
  The 84th Annual Meeting of the Japanese Society of Hematology
- Data Source
  KAKENHI-PROJECT-22K16294

1. 藤原亨

# of Collaborated Projects: 0 results

# of Collaborated Products: 3 results

Ono Koya 小野 浩弥

Research Projects

Research Products

Co-Researchers

Development of novel therapeutic approach for refractory anemia and malignant lymphoma by targeting ferroptosis suppressor protein-1Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

X連鎖性鉄芽球性貧血における鉄依存性細胞死および鉄代謝制御の解明Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

[Journal Article] Congenital sideroblastic anemia model due to ALAS2 mutation is susceptible to ferroptosis2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] TM5614, an Inhibitor of Plasminogen Activator Inhibitor-1, Exerts an Antitumor Effect on Chronic Myeloid Leukemia2022

Author(s)

Journal Title

DOI

ISSN

Language

Data Source

[Journal Article] T-cell receptor-silent peripheral T-cell lymphoma complicated with hemophagocytic lymphohystiocytosis2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Elucidation of the Role of FAM210B in Mitochondrial Metabolism and Erythropoiesis2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Exploring the mechanistic link between SF3B1 mutation and ring sideroblast formation in myelodysplastic syndrome2022

Author(s)

Journal Title

DOI

Data Source

[Presentation] Late-onset X-linked sideroblastic anemia due to heterozygous ALAS2 mutation: Insights from two adult female cases2022

Author(s)

Organizer

Data Source

[Presentation] Proteomic changes regulate ferroptosis susceptibility in X-linked sideroblastic anemia2022

Author(s)

Organizer

Data Source

[Presentation] Altered Transcription By GATA1 Impairs Autophagy and Prevents Ferroptosis in X-Linked Sideroblastic Anemia2022

Author(s)

Organizer

Data Source

[Presentation] Ferritinophagy is impaired in X-linked sideroblastic anemia models during differentiation2022

Author(s)

Organizer

Data Source

Ono Koya 小野浩弥