ISHIHARA Chiaki 石原智明

Researcher Number	90082172
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Affiliation (based on the past Project Information) *help	2012: 酪農学園大学, 獣医学群, 教授 2010 – 2011: 酪農学園大学, 獣医学部, 教授 1996 – 2006: 酪農学園大学, 獣医学部, 教授 1994 – 1998: 酪農学園大学, 酪農学部, 教授 1992 – 1993: 酪農学園大学, 獣医学科, 教授 … More 1991: 酪農学園大学, 獣医学科, 助教授 1990: Hokkaido Univ., Inst. Immunol. Sci. Associate Professor, 助教授 1989 – 1990: 北海道大学, 免疫科学研究所, 助教授 1988: 北海道大学, 免疫科学研究所・動物施設, 助教授 Less
Review Section/Research Field	Principal Investigator Laboratory animal science / Applied veterinary science / Basic veterinary science/Basic zootechnical science / Applied veterinary science Except Principal Investigator Basic veterinary science/Basic zootechnical science / Applied veterinary science / Immunology / Laboratory animal science / Applied veterinary science / Virology
Keywords	Principal Investigator Babesia microti / Babesia ovata / Theileria sergenti / SSUrRNA塩基配列 / 細菌の分類 / 実験動物 / 進化系統解析 / CCT7 遺伝子 / イントロン / 輸血感染症 … More / 新興感染症 / バベシア症 / 人獣共通感染症 / CCT7遺伝子 / 原虫クローン / 多様性 / 多型性マーカー / Parasite cloning / Polymorphic genes / Genetic markers / 動物モデル / scidマウス / NODマウス / 赤血球 / 住血原虫症 / SCIDマウス / Haemoparasite / Animal model / SCID mouse / NOD mouse / Erythrocyte / Haemoparasites / Babesia Theileria … More Except Principal Investigator SCIDマウス / Babesia ovata / Babesia microti / 動物モデル / 人獣共通感染症 / PCR / Animal model / Babesia bovis / ボルナ病ウイルス / zoonosis / PML / Caspase 3 / Bax / タイレリア原虫 / シゾント / 多様性 / 多型性マーカー / 原虫クローン / バベシア / リス / Sciurus / バベシア症 / Babesia rodhaini / ヒト赤血球 / 原虫表面抗原 / ムラミルジペプチジ(MDP)誘導体 / トレハロ-スジマイコレ-ト(TDM)誘導体 / B30ーMDP / MDPーLys(L18) / CMーキチン / 免疫アジュバント活性 / 腎症候性出血熱ウイルスワクチン / 癌ワクチン / ムラミルジペプチド(MDP)誘導体 / 免疫アジュバント / トレハロ-ス-マイコレ-ト / ムラミルジペプチド / マクロファ-ジ活性化 / 1-deoxy-glucosamine-mycolate / 癌転移抑制活性 / Muramyl dipeptide (MDP) derivatives / Trehalose-dimycolate (TDM) derivatives / B30-MDP / MDP-Lys (L18) / CM-chitin / Immunoadjuvant activity / Hantaan virus vaccine / Tumor vaccine / 腎症候性出血熱 / ハンタウイルス / ウイルス感染 / 動物実験 / 臨床生化学 / Scidマウス / Hemorrhagic fever with renal syndrome / Hantavirus / Scid mouse / Virus infection / Animal experiment / Clinical biochemistry / 感染モデル / 原虫性脳症 / 抗原変異 / Babesia / SCID mice / Cerebral babesiosis / Antigenic variation / 実験動物 / 海外感染病 / 診断法 / 防圧対策 / ウイルス学 / 細菌学 / 真菌学 / 寄生虫学 / 疫学的調査 / Laboratory animals / Emerging infections / Diagnosis / Disease control / Virology / Bacteriology / Mycology / Parasitology / 血液製剤 / 精神分裂病 / 慢性疲労症候群 / 献血者 / 血液 / 末梢血単核球 / 人畜共通感染症 / うつ病 / 抹消血単核球 / 輸血製剤 / ELISA / RT-PCR / NNS RNAウイルス / ELSA / Borna disease virus / blood product / schizophrenia / chronic fatigue syndrome / blood donor / blood / peripheral blood mononuclear cells / 輸血感染症 / 野生動物 / マダニ / 血清疫学 / アカネズミ / ダニ媒介性疾患 / Human babesiosis / Zoonosis / Transfision infection / Ticks / Ixodes ovatus / Wild animals / Apodemus speciosus / アポトーシス / 持続感染 / PML蛋白質 / IFN / BDV / aponptosis / 70%脱アセルチルキチン(DACー70) / アジュバント活性 / 硫酸化カルボキシメチルキチン(SCMーキチン) / 癌転移阻止 / カルボキシメチルキチン(CMーキチン) / ドラッグデリバリ-システム / 硫酸化キチン / 硫酸化キトサン / 免疫増強活性 / 癌転移抑制 / スルホン化キチン / スルホン化キトサン / 70% Deacetylated chitin (DAC-70) / Adjuvant Activity / Sulfated Carboxymethyl Chitin (SCM-chitin) / Prevention of Cancer Metastasis / Carboxymethyl-chitin (CM-chitin) / Drug delivery system Less

Intron Sequences in the CCT7 gene Show Diverse Evolutionary Histories of the Four Lineages withinthe "Babesia microti-Group," a Genetically Related Species-Complex Including Pathogens of Humans.Principal Investigator
- Principal Investigator
  
  ISHIHARA Chiaki
- Project Period (FY)
  2010 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Applied veterinary science
- Research Institution
  Rakuno Gakuen University
赤血球置き換えマウスモデルを用いた動物由来バベシア原虫のヒト赤血球への感染試験
- Principal Investigator
  
  辻正義
- Project Period (FY)
  2005 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Applied veterinary science
- Research Institution
  Rakuno Gakuen University
Study on Persistent infection of Borna Disease Virus in Brain
- Principal Investigator
  
  HAGIWARA Katsuro
- Project Period (FY)
  2003 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Applied veterinary science
- Research Institution
  Rakuno (kuen University
Epidemiological studies on babesiosis in humans and wild-life animals in Japan
- Principal Investigator
  
  TSUJI Masayoshi
- Project Period (FY)
  2000 – 2002
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Applied veterinary science
- Research Institution
  Rakuno Gakuen University
Red blood cell-substituted NOD-scid mouse model for erythroparasitic protozoan infections.Principal Investigator
- Principal Investigator
  
  ISHIHARA Chiaki
- Project Period (FY)
  1999 – 2000
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Applied veterinary science
- Research Institution
  Rakuno Gakuen University
バベシア原虫の染色体多型性マーカーの検索と有性生殖による交雑試験
- Principal Investigator
  
  辻正義
- Project Period (FY)
  1997 – 1998
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Basic veterinary science/Basic zootechnical science
- Research Institution
  Rakuno Gakuen University
Cloning of bovine hemoparasites and isolation of genetic markers for the parasite clonesPrincipal Investigator
- Principal Investigator
  
  ISHIHARA Chiaki
- Project Period (FY)
  1997 – 1998
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Basic veterinary science/Basic zootechnical science
- Research Institution
  Rakuno-gakuen University
STUDIES ON THE DlAGNOSIS, PREVENTION AND CONTROL OF EMERGING INFECTIOUS DISEASES IN LABORATORY ANIMALS
- Principal Investigator
  
  MAEJIMA Kazuyoshi
- Project Period (FY)
  1996 – 1998
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Laboratory animal science
- Research Institution
  KEIO UNIVERSITY
Safe blood products : Establishment of screening assay for Borna disease virus infection
- Principal Investigator
  
  IKUTA Kazuyoshi
- Project Period (FY)
  1996 – 1998
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Virology
- Research Institution
  Hokkaido University
Use of bovine-RBC-substituted SCID mice for the studies of Babesia parasites
- Principal Investigator
  
  TSUJI Masayoshi
- Project Period (FY)
  1995 – 1997
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Applied veterinary science
- Research Institution
  Rakuro-gakuen University
スポロザイトから赤内型原虫にまで至るタイレリア感染症のSCIDマウスモデル
- Principal Investigator
  
  TSUJI Masayoshi
- Project Period (FY)
  1994
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Basic veterinary science/Basic zootechnical science
- Research Institution
  Rakuno Gakuen University
リボゾーム遺伝子・配列を利用した実験動物感染症の簡易遺伝子診断Principal Investigator
- Principal Investigator
  
  石原智明
- Project Period (FY)
  1994
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Laboratory animal science
- Research Institution
  Rakuno Gakuen University
Genetical and biochemical characterizations of hemorrhagic fever with renal syndrome virus infection in mice.
- Principal Investigator
  
  ARIKAWA Jiro
- Project Period (FY)
  1991 – 1993
- Research Category
  
  Grant-in-Aid for Developmental Scientific Research (B)
- Research Field
  
  Laboratory animal science
- Research Institution
  Hokkaido University
Development of Immunoadjuvants for The Potentiation of Vaccine
- Principal Investigator
  
  AZUMA Ichiro
- Project Period (FY)
  1989 – 1990
- Research Category
  
  Grant-in-Aid for General Scientific Research (B)
- Research Field
  
  Immunology
- Research Institution
  Hokkaido University
Application of Chitin Derivatives to the Biomedical Materials
- Principal Investigator
  
  AZUMA Ichiro
- Project Period (FY)
  1987 – 1989
- Research Category
  
  Grant-in-Aid for Developmental Scientific Research (B).
- Research Field
  
  Immunology
- Research Institution
  Hokkaido University

All 2012 2011 2010 2006 2005 2003

All Journal Article Presentation

[Journal Article] Detection of two zoonotic Babesia microti, Hobetsu and U.S. lineages, respectively, in sympatric tick species, Ixodes ovatus and Ixodes persulcatus, in Japan2012
- Author(s)
  Zamoto-Niikura A., Tsuji M., Qiang W., Nakao M., Hirata H., Ishihara C
- Journal Title
  
  Appl Env Microbiol
  
  Volume: 78 :3424-3430
- Data Source
  KAKENHI-PROJECT-22580352
[Journal Article] Detection of two zoonotic Babesia microti, Hobetsu and U.S. lineages, respectively, in sympatric tick species, Ixodes ovatus and Ixodes persulcatus, in Japan2012
- Author(s)
  Zamoto-Niikura A., Tsuji M., Qiang W., Nakao M., Hirata H., Ishihara C.
- Journal Title
  
  Appl Env Microbiol
  
  Volume: 78 Pages: 3424-3430
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22580352
[Journal Article] Intron sequences from the CCT7 gene exhibit diverse evolutionary histories among the four lineages with the Babesia microti-group, a genetically related species complex that includes human pathogens2011
- Author(s)
  Fujisawa K., Nakajima R., Jinnai M., Hirata H., Zamoto-Niikura A., Kawabuchi-Kurata T., Arai S., Ishihara C.
- Journal Title
  
  Jpn.J.Infect.Dis.
  
  Volume: 64 Pages: 403-410
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22580352
[Journal Article] Intron sequences from the CCT7 gene exhibit diverse evolutionary histories among the four lineages with the Babesia microti-group, a genetically related species complex that includes human pathogens2010
- Author(s)
  Fujisawa K., Nakajima R., Jinnai M., Hirata H., Zamoto-Niikura A., Kawabuchi-Kurata T., Arai S., Ishihara C
- Journal Title
  
  Jpn. J. Infect. Dis
  
  Volume: 64:403-410
- Data Source
  KAKENHI-PROJECT-22580352
[Journal Article] Babesia microti-like parasites detected in Eurasian red squirrels (Sciurus vulgaris orientis) in Hokkaido, Japan.2006
- Author(s)
  Tsuji, M., Zamoto, A., Kawabuchi, T., Kataoka, T., Nakajima, R., Asakawa, M., Ishihara, C.
- Journal Title
  
  J.Vet.Med.Sci. 68巻7号
  
  Pages: 643-646
- NAID
  110004763170
- Data Source
  KAKENHI-PROJECT-17580269
[Journal Article] Babesia microti-like parasites detected in feral raccoons (Procyon lotor) captured in Hokkaido, Japan.2005
- Author(s)
  Kawabuchi, T., Tsuji, M., Sado, A., Matoba, Y., Asakawa, M., Ishihara, C.
- Journal Title
  
  J.Vet.Med.Sci. 67巻9号
  
  Pages: 825-827
- NAID
  110003983147
- Data Source
  KAKENHI-PROJECT-17580269
[Journal Article] Isolation of a human erythrocyte-adapted substrain of Babesia rodhaini and analysis of the merozoite surface protein gene sequences.2005
- Author(s)
  Kawabuchi, T., Tsuji, M., Kuwahara, S., Nishida, A., Shimofurutachi, T., Oka, H,.Ishihara, C.
- Journal Title
  
  J.Vet.Med.Sci. 67巻9号
  
  Pages: 901-907
- NAID
  110003983160
- Data Source
  KAKENHI-PROJECT-17580269
[Journal Article] The role of INF-gamma in cattle with Theileria segenti.2005
- Author(s)
  Hagiwara K., Tokuda M., Baba T., Yamanaka H., Kirisawa R., Tsuji M., Ishihara C., Iwai H.
- Journal Title
  
  Vet.Parasitol. 127巻2号
  
  Pages: 105-110
- Data Source
  KAKENHI-PROJECT-17580269
[Journal Article] The role of IFN-γ in cattle infected with Theirelia sergenti.2005
- Author(s)
  Hagiwara K, Tokuda M, Baba T, Yamanaka H, Kirisawa R, Tsuji M, Ishihara C, Iwai H
- Journal Title
  
  Vet.Parasitol. 127
  
  Pages: 105-110
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15580279
[Journal Article] Experimental vertical transmission of Borna disease virus in the mouse.2003
- Author(s)
  Okamoto M, Hagiwara K, Kamitani W, Sako T, Hirayama K, Kirisawa R, Tsuji M, Ishihara C, Iwai H, Kobayashi T, Tomonaga K, Ikuta K, Taniyama H
- Journal Title
  
  Arch Virol.Aug 148(8)
  
  Pages: 1557-1568
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15580279
[Presentation] B.microti原虫類の進化解析マーカーとしてのイントロン配列の有用性評価2010
- Author(s)
  藤澤幸平・中嶋瑠衣・陳内理生・平田晴之・新倉綾・倉田貴子・石原智明
- Organizer
  第150回日本獣医学会学術集会総会
- Place of Presentation
  帯広市稲田町帯広畜産大学
- Year and Date
  2010-09-17
- Data Source
  KAKENHI-PROJECT-22580352
[Presentation] B.microti 原虫類の進化解析マーカーとしてのイントロン配列の有用性評価2010
- Author(s)
  藤澤幸平・中嶋瑠衣・陳内理生・平田晴之・新倉綾・倉田貴子・石原智明
- Organizer
  第150回日本獣医学会学術集会総会
- Place of Presentation
  帯広市稲田町帯広畜産大学
- Year and Date
  2010-09-17
- Data Source
  KAKENHI-PROJECT-22580352

1. TSUJI Masayoshi (10150088)

# of Collaborated Projects: 8 results

# of Collaborated Products: 4 results
2. SAIGKI Ikuo (80133776)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
3. TOKURA Seiichi (40000806)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
4. HAGIWARA Katsurou (50295896)

# of Collaborated Projects: 2 results

# of Collaborated Products: 2 results
5. AZUMA Ichiro (50028411)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
6. ARIKAWA Jiro (10142704)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
7. YAMANISHI Koichi (10029811)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. ISEGAWA Yuji (20184583)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. YOSHIMATSU Kumiko (90220722)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. ITAKURA Chitoshi (30021695)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. HASHITOMO Nobuo (60082103)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. MIYAZAWA Masaaki (60167757)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
13. MAEJIMA Kazuyoshi (70051464)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
14. SATOH Hiroshi (50072947)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
15. SHIBAHARA Toshiyuki (70116937)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
16. URANO Toru (90101899)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
17. IKUTA Kazuyoshi (60127181)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
18. NISHINO Yoshii (00271544)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
19. ONO Etsuro (00160903)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
20. KIRISAWA Rikio (70153252)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
21. ISOGAI Emiko (80113570)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
22. MORITA Chiharu (50072369)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
23. SHIOTA Tsunezo (40128707)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
24. TANIYANMA Hiroyuki (90133800)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
25. SUGIMRUA Kazuhisa (80127240)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
26. 高橋清志 (90048108)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
27. 伊藤豊志雄 (20106644)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
28. 高橋樹史 (40240965)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
29. 片倉賢 (10130155)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
30. 川渕貴子 (70435890)

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
31. 新井智 (80321868)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
32. 毛利資郎 (40117271)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
33. 岸雅彦 (90161439)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
34. IMAI Mitsunobu

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
35. SEKIGUCHI Sadayoshi

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
36. SEO Hiroshi

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results

ISHIHARA Chiaki 石原 智明

Research Projects

Research Products

Co-Researchers

Intron Sequences in the CCT7 gene Show Diverse Evolutionary Histories of the Four Lineages withinthe "Babesia microti-Group," a Genetically Related Species-Complex Including Pathogens of Humans.Principal Investigator

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Red blood cell-substituted NOD-scid mouse model for erythroparasitic protozoan infections.Principal Investigator

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Cloning of bovine hemoparasites and isolation of genetic markers for the parasite clonesPrincipal Investigator

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リボゾーム遺伝子・配列を利用した実験動物感染症の簡易遺伝子診断Principal Investigator

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ISHIHARA Chiaki 石原智明