NAKAZAWA Shinpei 中澤眞平

… Alternative Names

中澤眞平ナカザワシンペイ

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Researcher Number	90090034
Other IDs
Affiliation (based on the past Project Information) *help	2006: University of Yamanashi, Department of Research Interdisciplinary Graduate School of Medicine and Engineering, Professor, 大学院医学工学総合研究部, 教授 2003 – 2005: University of Yamanashi, Interdisciplinary Graduate School of medicine and Engineering, Professor, 大学院・医学工学総合研究部, 教授 2002: 山梨大学, 医学部, 教授 1998 – 2001: 山梨医科大学, 医学部, 教授 1994 – 1995: 山梨医科大学, 医学部, 教授
Review Section/Research Field	Principal Investigator Pediatrics / Pediatrics
Keywords	Principal Investigator 11q23転座型白血病 / アポトーシス / CD33 / apoptosis / childhood leukemia / Philadelphia染色体陽性白血病 / 白血病 / 細胞傷害因子 / 細胞周期 / 難治性小児白血病 … More / 小児白血病 / G-CSF / LMO2 / t(17;19) / cytotoxic ligand / 11q23 translocation / FLT-3遺伝子 / PKC412 / BCR-ABL / Imatinib / 分子標的療法 / E2A-HLF / LMO2遺伝子 / 難治性白血病 / LM02 / 17;19転座 / 11q23転座 / GVL effect / all-SCT / TNF-family ligands / cytokine / cell cycle / chemo-resistance / 11q23転座型急性リンパ性白血病 / philadelphia染色体陽性白血病 / 移植片対白血病(GVL)効果 / 細胞周期停止 / HDAC inhibitor / 耐性機序 / STI571 / 造血因子 / T細胞型急性リンパ性白血病 / Philadelhia染色体陽性白血病 / GVL効果 / 同種造血幹細胞移植 / サイトカイン / 薬剤耐性 / Cytokine / Transcriptin factor / Translaocation / Chemotherapy / Apoptosis / Leukemia / 多剤耐性 / ステロイド剤 / 化学療法 / 小児急性リンパ性白血病 / 17;19転座型白血病 / 9;22転座型白血病 / プロモーター / 造血因子受容体 / 転写因子 / 転座型白血病 / 難治性小児急性白血病 / ABL / BCR / 小児急性白血病 Less

Establishment of new-therapy and analysis of mechanisms for resistance to apoptosis in poor-prognostic childhood leukemiaPrincipal Investigator
- Principal Investigator
  
  NAKAZAWA Shinpei
- Project Period (FY)
  2004 – 2006
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Pediatrics
- Research Institution
  University of Yamanashi
Resistance to apoptosis in childhood poor-prognostic leukemiaPrincipal Investigator
- Principal Investigator
  
  NAKAZAWA Shinpei
- Project Period (FY)
  2001 – 2003
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Pediatrics
- Research Institution
  University of Yamanashi
  山梨医科大学
The pivotal role of apoptosis in leukemogenesis and chemo-sensitivity in childhood leukemias.Principal Investigator
- Principal Investigator
  
  NAKAZAWA Shinpei
- Project Period (FY)
  1998 – 2000
- Research Category
  
  Grant-in-Aid for Scientific Research (B).
- Research Field
  
  Pediatrics
- Research Institution
  Yamanashi Medical University
小児BCR/ABL急性白血病に関する総合的研究-診断法の確立と治療への応用ならびに白血病細胞のG-CSF反応性の解析-Principal Investigator
- Principal Investigator
  
  中澤眞平
- Project Period (FY)
  1994 – 1995
- Research Category
  
  Grant-in-Aid for General Scientific Research (B)
- Research Field
  
  Pediatrics
- Research Institution
  山梨医科大学

All 2007 2006 2005 2004

All Journal Article

[Journal Article] Hypercalcemia in childhood acute lymphoblastic leukemia : frequent implication of PTHrP and E2A-HLF from translocation 17;19.2007
- Author(s)
  T Inukai, K Hirose, K Goi, Nakazawa, K Sugita, et al.
- Journal Title
  
  Leukemia 21
  
  Pages: 288-296
- Data Source
  KAKENHI-PROJECT-16390297
[Journal Article] Hypercalcemia in childhood acute lymphoblastic leukemia : frequent implication of PTHrP and E2A-HLF from translocation 17;19.2007
- Author(s)
  T Inukai, K Hirose, K Goi, S Nakazawa, K Sugita, et al.
- Journal Title
  
  Leukemia 21
  
  Pages: 288-296
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16390297
[Journal Article] Clonotypic analysis of acute lymphoblastic leukemia with a double TEL-AML1 fusion at onset and relapse.2006
- Author(s)
  Inukai T, Yokota S, Okamoto T, Nemoto A, Akahane K, Takahashi K, Sato H, Goi K, Nakazawa S, Sugita K.
- Journal Title
  
  Leukemia 20・2
  
  Pages: 363-365
- Data Source
  KAKENHI-PROJECT-16390297
[Journal Article] Clonotypic analysis of acute lymphoblastic leukemia with double TEL-AML1 fusion at onset and relapse.2006
- Author(s)
  Inukai T, Yokota S, Goi K, Nakazawa S, Sugita K et al.
- Journal Title
  
  Leukemia 20
  
  Pages: 363-365
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16390297
[Journal Article] Resistance of infant leukemia with MLL rearrangement to TNF-related apoptosis-induc ng ligand : a possible mechanism for poor sensitivity to antitumor immunity.2006
- Author(s)
  Inukai T, Hirose K, Goi K, Honna H, T, Nakazawa S, Sugita K, et al.
- Journal Title
  
  Leukemia 20
  
  Pages: 2119-2129
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16390297
[Journal Article] Natural pregnancy and delivery after allogeneic bone marrow transplantation in a Fanconi anaemia patient.2006
- Author(s)
  Goi K, Sugita K, Inukai T, Honna H, Hirose K, Nakazawa S, et al.
- Journal Title
  
  British Journal of Haematology 135
  
  Pages: 410-411
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16390297
[Journal Article] Resistance of infant leukemia with MLL rearrangement to TNF-related apoptosis-inducing ligand : a possible mechanism for poor sensitivity to antiumor immunity.2006
- Author(s)
  Inukai T, Hirose K, Goi K, Honna H, T, Nakazawa S, Sugita K, et al.
- Journal Title
  
  Leukemia 20
  
  Pages: 2119-2129
- Data Source
  KAKENHI-PROJECT-16390297
[Journal Article] A successful case of allogeneic bone marrow transplantation for osteosarcoma with multiple metastases of lung and bone.2006
- Author(s)
  Goi K, Sugita K, Tezuka T, Sato H, Uno K, Inukai T, Nakazawa S.
- Journal Title
  
  Bone Marrow Transplant 37・1
  
  Pages: 115-116
- Data Source
  KAKENHI-PROJECT-16390297
[Journal Article] Resistance of infant leukemia with MLL rearrangement to TNF-related apoptosis-inducing ligand : a possible mechanism for poor sensitivity to antitumor immunity.2006
- Author(s)
  Inukai T, Hirose K, Goi K, Honna H, T, Nakazawa S, Sugita K, et al.
- Journal Title
  
  Leukemia 20
  
  Pages: 2119-2129
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16390297
[Journal Article] Clonotypic analysis of acute lymphoblastic leukemia with a double TEL-AML1 fusion at onset and relapse.2006
- Author(s)
  Inukai T, Yokota S, Goi K, Nakazawa S, Sugita K et al.
- Journal Title
  
  Leukemia 20・2
  
  Pages: 363-365
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16390297
[Journal Article] Natural pregnancy and delivery after allogeneic bone marrow transplantation in a Fanconi anaemia patient.2006
- Author(s)
  Goi K, Sugita K, Nakamura M, Inukai T, Honna H, Hirose K, Kuroda I, Hoshi K, Nakazawa S.
- Journal Title
  
  British Journal of Haematology 135
  
  Pages: 410-411
- Data Source
  KAKENHI-PROJECT-16390297
[Journal Article] Induction of impaired membrane phospholipid asymmetry in mature erythrocyte after chemotherapy.2005
- Author(s)
  Zhang X, Inukai T, Hirose K, Akahane K.Nemoto A, Takahashi K, Sato H, Kagami K, Goi K, Sugita K, Nakazawa S.
- Journal Title
  
  International Journal of Hematology 82・2
  
  Pages: 132-136
- Data Source
  KAKENHI-PROJECT-16390297
[Journal Article] TFF, an anti-apoptotic bZIP transcription factor related to the oncogenic E2A-HLF chimera, inhibits cell growth by down regulating expression of the common {beta} chain of cytokine receptors.2005
- Author(s)
  Inukai T, Inaba T, K, Goi K, Sugita K, Nakazawa S. et al.
- Journal Title
  
  BLOOD (in press)
- Data Source
  KAKENHI-PROJECT-16390297
[Journal Article] Induction of impaired membrane phospholipid asymmetry in mature erythrocytes after chemotherapy.2005
- Author(s)
  Zhang X, Inukai T, Kagami K, Goi K, Sugita K, Nakazawa S e al.
- Journal Title
  
  International Journal of Hematology 82
  
  Pages: 132-136
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16390297
[Journal Article] TEF, an anti-apcptotic bZIP transcription factor related to the oncogenic E2A-HLF chimera, inhibits cell growth by downregulating expression of the common b chain of cytokine receptors.2005
- Author(s)
  T.Inukai, Y.Arinobu, H.Iwasaki, K.Akashi, K.Kagami, K.Goi, K.Sugita, S.Nakazawa.et al.
- Journal Title
  
  Blood 105・11
  
  Pages: 4437-4444
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16390297
[Journal Article] TEF, an anti-apoptotic bZIP transcription factor related to the oncogenic E2A-HLF chimera, inhibits cell growth by downregulating expression of the common b chain of cytokine receptors.2005
- Author(s)
  T.Inukai, Y.Arinobu, H.Iwasaki, K.Akashi, K.Kagami, K.Goi, K.Sugita, S.Nakazawa et al.
- Journal Title
  
  Blood 105
  
  Pages: 4437-4444
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16390297
[Journal Article] TEF, an anti-apoptotic bZIP transcription factor related to the oncogenic E2A-HLF chimera, inhibits cell growth by downregulating expression of the common β chain of cytokine receptors.2005
- Author(s)
  T.Inukai, T.Inaba, J.Dang, R.A.T.Look, Y.Arinobu, H.Iwasaki, K.Akashi, K.Kagami, K.Goi, K.Sugita, S.Nakazawa et al.
- Journal Title
  
  Blood 105・11
  
  Pages: 4437-4444
- Data Source
  KAKENHI-PROJECT-16390297
[Journal Article] Induction of impaired membrane phospholipid asymmetry in mature erythrocytes after chemotherapy.2005
- Author(s)
  Zhang X, Inukai T, Kagami K, Goi K, Sugita K, Nakazawa S et al.
- Journal Title
  
  International Journal of Hematology 82・2
  
  Pages: 132-136
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16390297
[Journal Article] Hepatocyte growth factor protects small airway epithelial calls from apoptosis induced by tumor necrosis factor-alpha or oxidative stress.2004
- Author(s)
  Okada M, Sugita K, Inukai T, Goi K, Kagami K, Kawasaki K, Nakazawa S.
- Journal Title
  
  Pediatr Res 56・3
  
  Pages: 336-344
- Data Source
  KAKENHI-PROJECT-16390297
[Journal Article] Roles of Bim in apoptosis of normal and Bcr-Abl-expressing hematopoietic progenitors.2004
- Author(s)
  Kuribara R, Inukai T, Sugita K, Nakazawa S, Inaba T. et al.
- Journal Title
  
  Mol Cell Biol 24・12
  
  Pages: 6172-6183
- Data Source
  KAKENHI-PROJECT-16390297

1. SUGITA Kanji (60138055)

# of Collaborated Projects: 4 results

# of Collaborated Products: 20 results
2. GOI Kumiko (70324192)

# of Collaborated Projects: 3 results

# of Collaborated Products: 19 results
3. INUKAI Takeshi (30293450)

# of Collaborated Projects: 3 results

# of Collaborated Products: 20 results
4. AKAHANE Koshi (90377531)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
5. HONNA Hiroko (50377537)

# of Collaborated Projects: 1 results

# of Collaborated Products: 5 results
6. 斎藤みどり (20170532)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. 飯島純

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. 手塚徹

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results

NAKAZAWA Shinpei 中澤 眞平

中澤 眞平 ナカザワ シンペイ

Research Projects

Research Products

Co-Researchers

Establishment of new-therapy and analysis of mechanisms for resistance to apoptosis in poor-prognostic childhood leukemiaPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Resistance to apoptosis in childhood poor-prognostic leukemiaPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

The pivotal role of apoptosis in leukemogenesis and chemo-sensitivity in childhood leukemias.Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

小児BCR/ABL急性白血病に関する総合的研究-診断法の確立と治療への応用ならびに白血病細胞のG-CSF反応性の解析-Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Hypercalcemia in childhood acute lymphoblastic leukemia : frequent implication of PTHrP and E2A-HLF from translocation 17;19.2007

Author(s)

Journal Title

Data Source

[Journal Article] Hypercalcemia in childhood acute lymphoblastic leukemia : frequent implication of PTHrP and E2A-HLF from translocation 17;19.2007

Author(s)

Journal Title

Description

Data Source

[Journal Article] Clonotypic analysis of acute lymphoblastic leukemia with a double TEL-AML1 fusion at onset and relapse.2006

Author(s)

Journal Title

Data Source

[Journal Article] Clonotypic analysis of acute lymphoblastic leukemia with double TEL-AML1 fusion at onset and relapse.2006

Author(s)

Journal Title

Description

Data Source

[Journal Article] Resistance of infant leukemia with MLL rearrangement to TNF-related apoptosis-induc ng ligand : a possible mechanism for poor sensitivity to antitumor immunity.2006

Author(s)

Journal Title

Description

Data Source

[Journal Article] Natural pregnancy and delivery after allogeneic bone marrow transplantation in a Fanconi anaemia patient.2006

Author(s)

Journal Title

Description

Data Source

[Journal Article] Resistance of infant leukemia with MLL rearrangement to TNF-related apoptosis-inducing ligand : a possible mechanism for poor sensitivity to antiumor immunity.2006

Author(s)

Journal Title

Data Source

[Journal Article] A successful case of allogeneic bone marrow transplantation for osteosarcoma with multiple metastases of lung and bone.2006

Author(s)

Journal Title

Data Source

[Journal Article] Resistance of infant leukemia with MLL rearrangement to TNF-related apoptosis-inducing ligand : a possible mechanism for poor sensitivity to antitumor immunity.2006

Author(s)

Journal Title

Description

Data Source

[Journal Article] Clonotypic analysis of acute lymphoblastic leukemia with a double TEL-AML1 fusion at onset and relapse.2006

Author(s)

Journal Title

Description

Data Source

[Journal Article] Natural pregnancy and delivery after allogeneic bone marrow transplantation in a Fanconi anaemia patient.2006

Author(s)

Journal Title

Data Source

[Journal Article] Induction of impaired membrane phospholipid asymmetry in mature erythrocyte after chemotherapy.2005

NAKAZAWA Shinpei 中澤眞平

中澤眞平ナカザワシンペイ