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saji fumitaka  佐治 文隆

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SAJI Fumitaka  佐治 文隆

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Researcher Number 90093418
External Links
Affiliation (Current) 2025: 独立行政法人国立病院機構(呉医療センター臨床研究部), その他部局等, その他
Affiliation (based on the past Project Information) *help 1996 – 1998: Osaka Univ.Med.School Dept.of Obstet.and Gyne.associate professor, 医学部, 助教授
1987 – 1995: 大阪大学, 医学部, 講師
1988: 医学部・産婦人科, 講師
1988: 大阪大学, 医学部産科婦人科, 講師
1986: 阪大, 医学部, 講師
Review Section/Research Field
Principal Investigator
Obstetrics and gynecology
Except Principal Investigator
Obstetrics and gynecology
Keywords
Principal Investigator
IL-6 / hCG / U-Maf / CD46 / Oxytocin receptor / Apoptosis / LIF / Decidua / Trophoblast / TIMP … More / MMP / 先体反応 / 精子不動化試験 / 不妊 / sperm immobilization test / sperm cell membrane glycoprotein / human sperm antigen / 精子細胞膜糖蛋白 / ヒト精子抗原 / DNA binding protein / Mammary gland / N-gycosylation pont mutation / 脱感作現象 / 突然変異体 / 遺伝的背景 / 早期発現 / 早産 / DNA結合蛋白 / 乳腺 / 点突然変異 / 糖鎖修飾部位 / オキシトシン受容体 / acrobeads test / acrosome reaction / fertilizing capacity / human spermatozoa / 男性不妊 / 細胞融合 / 受精 / 精子 / アクロビーズテスト / 受精能 / ヒト精子 / オキシトシン・レセプター / フィブロネクチン / IL‐6 / アポトーシス / 胎盤絨毛 / oxytocin receptor / TNF-alpha / TGF-beta / cytokine / Extracellular matrix / 胎盤絨毛細胞 / zymography / 子宮内膜 / 着床 / TNF-α / TGF-β / サイトカイン / 細胞外マトリックス / acrosomal reaction / monoclonal antibody / Sperm immobilizing test / ELISA / Capacitation / Infertility / Antisperm antibody / capacitation / モノクロ-ナル抗体 / 酵素抗体法 / Capacitalion / 抗精子抗体 … More
Except Principal Investigator
Trophoblast / 胎盤 / 絨毛細胞 / 絨毛癌 / placenta / Maternal T cells / LAK cells / Immunoregulation / Pregnancy / HCG / CD46 / dysplasia / SNRPN / H19 / IGF2 / HLA-G / オキシトシン受容体遺伝子 / trophoblast / mRNA / Cytokine / サイトカイン / TIMP / 子宮内膜癌 / CAGY領域 / 絨毛性ゴナドトロピン / 繊毛細胞 / インタ-ロイキン6(ILー6) / T細胞調節機序 / 妊娠 / Maternol T cells / Xenopus Oocytes / Invitro translation / Invitro transcription / Invitro metagenesis / CAGY region / Beta subunit / in vitro transcription and transletion / point mutation / ヒト絨毛性ゴナドトロビン / 先天性TSH欠損症 / Enzyme-imonuro assay / アフリカツメガエル卵母細胞 / in vitro transcription / DNAシ-クエンス / in vitro mutagenesis system / Gly→Arg、Asp変換 / アフリカツメガエル / 塩基置換 / α鎖、β鎖、CDNA / ブル-スクリプトベクタ- / α鎖、β鎖 / fertilization / acrosome reaction / human oocyte / human spermatozoa / 受精分子 / 先体反応 / ヒト卵 / ヒト精子 / genomic lmprinting / telomerase / mol gene / PXGR gene / CIS / テロメアーゼ活性 / モータリン蛋白 / クロナリティー / CIS病変 / 子宮頸部上皮内病変 / genomicimprinting現象 / genomic imprinting現象 / テロメラーゼ活性 / mol遺伝子 / PXGR遺伝子 / 異型上皮病変 / 子宮頚部癌 / regulatory element / N-glycosylation / oxytocin binding capacity / oxytocin unresponsiveness / ゲルシフトアッセイ / 発見調節領域 / 糖鎖 / 発現調節領域 / オキシトシン結合能 / 遺伝子多型 / オキシトシン不応症 / 遷延分娩 / ovarian choriocarcinoma / human imprinted genes / genomic imprinting / IGF2.H19.SNRPN遺伝子 / HLA-G遺伝子 / ゲノム・インプリント解除 / 胚細胞系腫瘍 / HI9 / 絨毛癌再 / 良性卵巣奇形腫 / ゲノムインプリンティング / bystander killing effect / ganciclovir / thymidine kinase / cervical adenocarcinoma / herpes virus / endometrial cancer / gene therapy / 婦人科癌 / バイスタンダー効果 / ガンシクロビル / チミヂンキナーゼ / ヘルペスウイルス / 遺伝子治療 / 子宮頚部腺癌 / Gene-targeting / Parturition / Molecular cloning / Oxytocin receptor gene / 遺伝子クローニング / ウェスタンブロッティング / ノーザンブロッティング / 免疫組織染色 / in situハイブリダイゼーション / オキシトシンレセプター / ノックアウトマウス / 分娩 / クローニング / Gel mobility shift assay / NF-kappaB / nuclear factor / Choriocarcimoma / Major histocompatibility / 転写因子 / 免疫学的妊娠維持機溝 / ゲル移動度シフト法 / NF-kB / 核蛋白 / 絨毛癌細胞株 / 主要組織適合抗原 / transcriptional regulation / gene / monoclonal antibodies / transient expression / oxytocin receptor / oxytocin / 抗ヒトオキシトシン抗体 / in situ hybridization / 5′上流領域 / 一過性発現系 / 転写調節領域 / 遺伝子 / モノクローナル抗体 / 一過性発現 / オキシトシン受容体 / オキシトシン / endometrium / Ovary / Pituitary / Gonadal steroids / 絨毛膜細胞 / 子宮内膜 / 卵巣 / 下垂体 / 性ステロイド / RDS / Chorioamnionitis / Fetomaternal defense mechanism / Perinatal infection / Endocrine function / タイロシン蛋白酵素 / 細胞内情報伝達経路 / ホルモン分泌調節 / 呼吸窮迫症候群 / 絨毛羊膜炎 / 母児生体防御能 / 周産期感染症 / ホルモン分泌調節機序 / ovarian cancer / zymography / endometrial carcinoma / gelatinase / typeIV collagenase / tumor invasion / 92KDa4型コラゲナーゼ / 220KDa4型コラゲナーゼ / 92KDaIV型コラゲナーゼ / 220KDaIV型コラゲナーゼ / ザイモグラフィー / 卵巣癌 / ザイモグラフィ / ジェラチナーゼ / タイプNコラゲナーゼ / 腫瘍浸潤 / Site-directed Mutagenesis / Point Mutation / CAGY Region / Beta Subunit / Alpha Subunit / thyroid Stimulating Hormone / Human chorionic Gonadotropin / chorionic / 卵母細胞微量RNA注入 / 試験管内転写 / 遺伝子組換 / 黄体ホルモン / ヒト絨毛ゴナドトロピン / hCG / βサブユニット / αサブユニット / siteーdivected mutaguresis / 点突然変異 / 甲状腺刺激ホルモン / placental Hormone / trophoblasts / hCG (human chorionic gonadotropin (hCG) / TGF-beta (transforming grothfactor) / TNF-alpha / Interleukin-1 / IL-6-receptor / Interleukin-6 (IL-6) / 腫瘍壊死因子(TNFーα) / インタ-ロイキン1 / インタ-ロイキン6レセプタ- / hCG(human chonoue gonadotropn) / TGFーβ(transtorming growth factorーβ) / TNFーα(tumor necusis factorーα) / ILー1(interleukinー1) / インタ-ロイキン(ILー6) / 胎盤ホルモン / hCG(human choninic gonadutropn) / TGFーβ(transformng growth factorーβ) / TNFーα(tumor rneowsis factorーα) / ILー1(interlenlGnー1) / ILー6レセプタ-(ーR) / Human chorionic gonadotropin / Interleukin-6 receptor / Interleukin-6 / インタ-ロイキン6 / ヒト胎盤 / 繊毛性ゴナドトロピン刺激ホルモン / ヒト繊毛性ゴナドトロピン(hCG) / 絨毛性ゴナドトロピン刺激ホルモン / ヒト絨毛性ゴナドトロビン(hCG) / インタ-ロイキン6レセプタ-(ILー6R) / Macrophage colony-stimulating factor / Mitochondrial DNA / Androgeners / Choriocarcinoma / Hydatidiform mole / DNA fingerprint / c-fms / MCSF / ノ-ザンブロットハイブリダイゼ-ション / サザンブロットハイブリダイゼ-ション / ミニサテライトDNAプロ-ブ / マクロファ-ジコロニ-刺激因子 / ミトコンドリアDNA / 雄性発生 / 胞状奇胎 / DNA指紋 Less
  • Research Projects

    (23 results)
  • Co-Researchers

    (25 People)
  •  Analysis of the genetic background of preterm labor using oxytocin receptor gene.Principal Investigator

    • Principal Investigator
      KANZAKI Toru, 佐治 文隆
    • Project Period (FY)
      1997 – 1998
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Obstetrics and gynecology
    • Research Institution
      Osaka University
  •  Comparison of pathogenesis between human uterine cervical dysplasia and carcinoma in situ

    • Principal Investigator
      AZUMA Chihiro
    • Project Period (FY)
      1997 – 1998
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Obstetrics and gynecology
    • Research Institution
      Osaka University
  •  Analysis of molecules for fertilization on human spermatozoa and oocytes

    • Principal Investigator
      OHASHI Kazutomo
    • Project Period (FY)
      1997 – 1998
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Obstetrics and gynecology
    • Research Institution
      Osaka University
  •  The analysis of genomic imprinting in ovarian teratomas and choriocarcinoma

    • Principal Investigator
      SIMOYA Kouichirou
    • Project Period (FY)
      1996 – 1997
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Obstetrics and gynecology
    • Research Institution
      Osaka University
  •  Analysis of the oxytocin unresponsiveness due to the mutant oxytocin receptor.

    • Principal Investigator
      TOKUGAWA Yoshihiro
    • Project Period (FY)
      1996 – 1997
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Obstetrics and gynecology
    • Research Institution
      Osaka University
  •  Analysis of labor onset by construction of oxytocin receptor deficient mice

    • Principal Investigator
      AZUMA Chihiro
    • Project Period (FY)
      1995 – 1996
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Obstetrics and gynecology
    • Research Institution
      Osaka University
  •  Molecular analysis of fertilizing ability in human spermatozoaPrincipal Investigator

    • Principal Investigator
      SAJI Fumitaka
    • Project Period (FY)
      1995 – 1996
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Obstetrics and gynecology
    • Research Institution
      Osaka University
  •  Bystander killing effect in gynecological cancer.

    • Principal Investigator
      SAMEJIMA Yoshihiro
    • Project Period (FY)
      1995 – 1996
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Obstetrics and gynecology
    • Research Institution
      Osaka University
  •  Moleccular analysis of human leukocyto antigens in trophblast derived cells

    • Principal Investigator
      KOYAMA Masayasu
    • Project Period (FY)
      1994 – 1995
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      Obstetrics and gynecology
    • Research Institution
      Osaka University
  •  The role of cytokines in reprodution and embryogenesis

    • Principal Investigator
      MORI Takahide
    • Project Period (FY)
      1993 – 1994
    • Research Category
      Grant-in-Aid for Co-operative Research (A)
    • Research Field
      Obstetrics and gynecology
    • Research Institution
      KYOTO UNIVERSITY
  •  Molecular analysis of human parturition using oxytocin receptor

    • Principal Investigator
      KIMURA Tadashi
    • Project Period (FY)
      1993 – 1994
    • Research Category
      Grant-in-Aid for General Scientific Research (B)
    • Research Field
      Obstetrics and gynecology
    • Research Institution
      Osaka University
  •  Studies of human trophoblast derived factors which regulate fetal and placental developmentPrincipal Investigator

    • Principal Investigator
      SAJI Fumitaka
    • Project Period (FY)
      1993 – 1994
    • Research Category
      Grant-in-Aid for General Scientific Research (B)
    • Research Field
      Obstetrics and gynecology
    • Research Institution
      Osaka University
  •  The study to the role of extra-cellular marorix in the metastasis and invesion of malignat tumor of gynecological field

    • Principal Investigator
      TANIZAWA Osamu, 谷澤 修
    • Project Period (FY)
      1992 – 1993
    • Research Category
      Grant-in-Aid for General Scientific Research (B)
    • Research Field
      Obstetrics and gynecology
    • Research Institution
      Osaka University
  •  Analysis of placental endocrine and immunological function regulated by placenta-derived cytokines

    • Principal Investigator
      MITSUDA Nobuaki
    • Project Period (FY)
      1992 – 1993
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      Obstetrics and gynecology
    • Research Institution
      Osaka University
  •  Interactions between early trophoblast cells and uterine endometrial cells at implantationPrincipal Investigator

    • Principal Investigator
      SAJI Fumitaka
    • Project Period (FY)
      1991 – 1992
    • Research Category
      Grant-in-Aid for General Scientific Research (B)
    • Research Field
      Obstetrics and gynecology
    • Research Institution
      Osaka University
  •  Regulation of placental hormone selease by trophoblast-derived IL-6

    • Principal Investigator
      MATSUZAKI Noboru
    • Project Period (FY)
      1990 – 1991
    • Research Category
      Grant-in-Aid for General Scientific Research (B)
    • Research Field
      Obstetrics and gynecology
    • Research Institution
      Osaka University
  •  Analysis of hCG and LH active site by using molecular biological method

    • Principal Investigator
      TANIZAWA Osamu
    • Project Period (FY)
      1990 – 1991
    • Research Category
      Grant-in-Aid for General Scientific Research (B)
    • Research Field
      Obstetrics and gynecology
    • Research Institution
      Osaka University
  •  Studies on the Pathogenesis of Trophoblastic Tumors by DNA Fingerprint and its Relationship With Growth Factor

    • Principal Investigator
      KOYAMA Masayasu, AZUMA Chihiro
    • Project Period (FY)
      1989 – 1990
    • Research Category
      Grant-in-Aid for General Scientific Research (B)
    • Research Field
      Obstetrics and gynecology
    • Research Institution
      Osaka University Medical School
  •  Analysis of the Reproductive Failure by Using Monoclonal Antibodies Against Human SpermPrincipal Investigator

    • Principal Investigator
      SAJI Fumitaka
    • Project Period (FY)
      1989 – 1990
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      Obstetrics and gynecology
    • Research Institution
      Osaka University Medical School
  •  Analysis of Interleukin-6-Mediated Regulation of Placental Functions

    • Principal Investigator
      TAKAGI Tetsu, KAMEDA T.
    • Project Period (FY)
      1989 – 1990
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      Obstetrics and gynecology
    • Research Institution
      Department of obstetrics & Gynecology, Osaka University Medical School.
  •  Identification of the region in the hCG cDNA associating its bioactivity by using biotechnology

    • Principal Investigator
      TANIZAWA Osamu
    • Project Period (FY)
      1988 – 1989
    • Research Category
      Grant-in-Aid for General Scientific Research (B)
    • Research Field
      Obstetrics and gynecology
    • Research Institution
      OSAKA UNIVERSITY
  •  Analysis of Immunoregulation in establishment and maintenance of pregnancy

    • Principal Investigator
      MATSUZAKI N.
    • Project Period (FY)
      1988 – 1989
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      Obstetrics and gynecology
    • Research Institution
      Osaka University Medical School
  •  Development of the enzyme-linked immunosorbent assay kit for sperm-immobilizing antibodies.Principal Investigator

    • Principal Investigator
      SAJI Fumitaka
    • Project Period (FY)
      1986 – 1988
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      Obstetrics and gynecology
    • Research Institution
      Osaka University
  • 1.  OHASHI Kazutomo (30203897)
    # of Collaborated Projects: 17 results
    # of Collaborated Products: 0 results
  • 2.  AZUMA Chihiro (20151061)
    # of Collaborated Projects: 14 results
    # of Collaborated Products: 0 results
  • 3.  KOYAMA Masayasu (00183351)
    # of Collaborated Projects: 10 results
    # of Collaborated Products: 0 results
  • 4.  KAMIURA Syoji (10243213)
    # of Collaborated Projects: 6 results
    # of Collaborated Products: 0 results
  • 5.  SHIMOYA Kouichiro (40291950)
    # of Collaborated Projects: 5 results
    # of Collaborated Products: 0 results
  • 6.  MATSUZAKI Noboru (30199781)
    # of Collaborated Projects: 5 results
    # of Collaborated Products: 0 results
  • 7.  TOKUGAWA Yoshihiro (70283786)
    # of Collaborated Projects: 5 results
    # of Collaborated Products: 0 results
  • 8.  KIMURA Tadashi (90240845)
    # of Collaborated Projects: 4 results
    # of Collaborated Products: 0 results
  • 9.  SAMEJIMA Yoshihiro (30231351)
    # of Collaborated Projects: 4 results
    # of Collaborated Products: 0 results
  • 10.  TAKEMURA Masahiko
    # of Collaborated Projects: 4 results
    # of Collaborated Products: 0 results
  • 11.  TANIZAWA Osamu (30028443)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 0 results
  • 12.  HASHIMOTO Kazumasa
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 0 results
  • 13.  KAMEDA T. (70204641)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 14.  MITSUDA Nobuaki (50209805)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 15.  KANZAKI Toru (00263278)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 16.  NOBUNAGA Toshikatsu
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 17.  TAKAGI Tetsu (10150343)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 18.  MORI Takahide (90026865)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 19.  AONO Toshihiro (50028445)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 20.  TOMODA Yutaka (60023769)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 21.  FUJITA Jun (50173430)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 22.  TAKAHASHI Michio (30011943)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 23.  MURATA Yuji (40283759)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 24.  NEGORO Takao (00112053)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 25.  久保田 康愛
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results

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