FUJIWARA Hideaki 藤原英明

… Alternative Names

藤原秀明フジワラヒデアキ

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Researcher Number	90107102
Other IDs
External Links
Affiliation (based on the past Project Information) *help	2015: 大阪大学, 名誉教授 2004: Osaka University, Graduate School of Medicine, Professor, 大学院・医学系研究科, 教授 2003: 大阪大学, 医学系研究科, 教授 1995 – 2002: 大阪大学, 医学部, 教授 1999: 大阪大学, 医学系研究科, 教授 1994: 大阪大学, 薬学部, 教授
Review Section/Research Field	Principal Investigator Radiation science / Science and Engineering / Biological Sciences Except Principal Investigator Physical pharmacy / Circulatory organs internal medicine / Biomedical engineering/Biological material science
Keywords	Principal Investigator MRI / MRS / Xe NMR / 超偏極希ガス / 生体温度測定 / NMR / コンホメーション / 液晶NMR法 / イオノホア / Lung Function … More / Brain Function / Mouse / Hyperpolarized Noble Gas / エマルジョン / 肺機能評価 / 肺画像 / 肺機能測定 / 脳機能測定 / マウス / 希釈ガス / 偏極率 / 磁気的相互作用 / 磁化移動 / エンタルピー / 平衡定数 / カリックスアレン / 包接相互作用 / Xe-129 / 二次元NMR / エマルジェン / 体内温度測定 / 多核種内部基準法 / 温度依存性 / Xe-129化学シフト / 超偏極希ガスNMR / 配向パラメーター / ジニコナゾール / ウニコナゾール / 直接結合定数 / 絶対構造決定 / 光学純度 / キラル液晶 / 光学異性体 / ネマティック液晶 / 分子内水素結合 / 選択緩和実験 / 2-vinyloxypyridine / 固体高分解能NMR / C-13NMR / 液晶NMR / エンケファリン / ラザロシッドA / 二次元NMR法 / 膜透過速度 / 金属イオン … More Except Principal Investigator ニューラルネットワーク / Contrast media / Circulation / Ultrasound / 気泡 / 造影剤 / 超音波 / 病態モデル / MRS / 生体磁気共鳴計測 / 超偏極希ガス / 超偏極 / 前臨床評価系 / 慢性閉塞性肺疾患 / イメージング / 難治性肺疾患 / 新薬探索 / 前臨床評価 / 肺機能診断 / MRI / 超偏極キセノン / Pharmacoepidemiology / Pharmainformatics / Metric Pharmacy / Artificial Neural Network / Decision Tree / Nonparametric Regression / Nonlinear Analysis / 平滑化法 / 薬剤疫学 / 情報薬学 / 計量薬学 / 決定木 / ノンパラメトリック回帰 / 非線形解析 / perfusion / Ischemic Heart Disease / 冠循環 / 弗素ガス / Shift Test Method / Computer Statistics / Robust Estimation / Neural Networks / QSAR / 医薬品分子設計 / シフト検定法 / 計算機統計学 / ロバスト推定法 / 定量的構造活性相関 / bubble / Fluorcarbon / 循環 / 弗素化合物 Less

Development of preclinical system based on pulmonary functional imaging by hyperpolarized Xe MRI
- Principal Investigator
  
  Kimura Atsuomi
- Project Period (FY)
  2012 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Biomedical engineering/Biological material science
- Research Institution
  Osaka University
簡易連続型超偏極希ガス生成装置の試作と水素や炭素核の高感度MRI実験への応用Principal Investigator
- Principal Investigator
  
  藤原英明
- Project Period (FY)
  2002 – 2004
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Radiation science
- Research Institution
  Osaka University
Applied Clinical Study on Hyperpolarized Noble Gas MRI/MRS using Pathologic Model AnimalPrincipal Investigator
- Principal Investigator
  
  FUJIWARA Hideaki
- Project Period (FY)
  2002 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Radiation science
- Research Institution
  Osaka University
液晶NMR法におけるキラル液晶系の利用と天然分子の絶対構造決定の開発Principal Investigator
- Principal Investigator
  
  藤原英明
- Project Period (FY)
  2001 – 2002
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Science and Engineering
- Research Institution
  Osaka University
超偏極希ガス簡易供給装置の開発と高感度磁気共鳴による脳機能計測の研究Principal Investigator
- Principal Investigator
  
  藤原英明
- Project Period (FY)
  2001 – 2002
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Osaka University
磁気的な直接結合定数を利用した構造解析法の開発と微量天然物への応用展開研究Principal Investigator
- Principal Investigator
  
  藤原英明
- Project Period (FY)
  2000
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (A)
- Review Section
  
  Science and Engineering
- Research Institution
  Osaka University
Non-linear Analysis of Medical and Pharmaceutical Data using Neural Network and Generalized Additive Model
- Principal Investigator
  
  TAKAGI Tatsuya
- Project Period (FY)
  1999 – 2000
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Physical pharmacy
- Research Institution
  Osaka University
Skill of intravenous ultrasonic contrast agent for evaluation of microcirculation of human organs and its assessment for clinical use.
- Principal Investigator
  
  BEPPU Shintaro
- Project Period (FY)
  1998 – 2000
- Research Category
  
  Grant-in-Aid for Scientific Research (B).
- Research Field
  
  Circulatory organs internal medicine
- Research Institution
  Osaka University
Improvement of Artificial Neural Networks and Its Applications to QSARs.
- Principal Investigator
  
  TAKAGI Tatsuya
- Project Period (FY)
  1996 – 1997
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Physical pharmacy
- Research Institution
  Osaka University
A Novel Agent for Contrast Echocardiography and its Evaluation in a Distinctive Clinical Application.
- Principal Investigator
  
  BEPPU Shintaro
- Project Period (FY)
  1995 – 1996
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Circulatory organs internal medicine
- Research Institution
  Osaka University
金属イオンの膜透過性を支配する天然超分子のNMRによる研究Principal Investigator
- Principal Investigator
  
  藤原英明
- Project Period (FY)
  1994
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Osaka University
金属イオンの膜透過性を支配する天然超分子のNMRによる研究Principal Investigator
- Principal Investigator
  
  藤原英明
- Project Period (FY)
  1994 – 1995
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Osaka University

All 2016 2015 2014 2013 2004 2003 Other

All Journal Article Presentation Book

[Book] Hyperpolarized Xenon-129 Magnetic Resonance.2015
- Author(s)
  Kimura A, Imai H, Fujiwara H.
- Total Pages
  16
- Publisher
  Royal Society of Chemistr
- Data Source
  KAKENHI-PROJECT-24300163
[Book] Hyperpolarized Xenon-129 Magnetic Resonance2015
- Author(s)
  Kimura A, Imai H, Fujiwara H
- Total Pages
  483
- Publisher
  Cambridge: Royal Society of Chemistry
- Data Source
  KAKENHI-PROJECT-24300163
[Book] Quantitation in Biomedical Imaging with RET and MRI, ICS1265.2004
- Author(s)
  M.Narazaki, T.Wakayama, A.Kimura, H.Fujiwara
- Total Pages
  4
- Publisher
  Elsevier, Amsterdam
- Data Source
  KAKENHI-PROJECT-14657215
[Book] Quantitation in Biomedical Imaging with PET and MRI, ICS1265.2004
- Author(s)
  T.Wakayama, T.Oose, M.Narazaki, A.Kimura, H.Fujiwara
- Total Pages
  4
- Publisher
  Elsevier, Amsterdam
- Data Source
  KAKENHI-PROJECT-14370277
[Book] Quantitation in Biomedical Imaging with PET and MRI, ICS1265.2004
- Author(s)
  T.Wakayama, T.Oose, M.Narazaki, A.Kimura, H.Fujiwara
- Total Pages
  4
- Publisher
  Elsevier, Amsterdam
- Data Source
  KAKENHI-PROJECT-14657215
[Book] Quantitation in Biomedical Imaging with PET and MRI, ICS1265.2004
- Author(s)
  M.Narazaki, T.Wakayama, A.Kimura, H.Fujiwara
- Total Pages
  4
- Publisher
  Elsevier, Amsterdam
- Data Source
  KAKENHI-PROJECT-14370277
[Book] Quantitation in Biomedical Imaging with PET and MRI, ICS1265.2004
- Author(s)
  H.Fujiwara, A.Kimura, T.Wakayama
- Total Pages
  8
- Publisher
  Elsevier, Amsterdam
- Data Source
  KAKENHI-PROJECT-14370277
[Book] Quantitation in Biomedical Imaging with PET and MRI, ICS1265.2004
- Author(s)
  H.Fujiwara, A.Kimura, T.Wakayama
- Total Pages
  8
- Publisher
  Elsevier, Amsterdam
- Data Source
  KAKENHI-PROJECT-14657215
[Book] Quantitation in Biomedical Imaging with PET and MRI, ICS1265.2004
- Author(s)
  Y.Kawata, T.Kamiya, H.Miura, A.Kimura, H.Fujiwara
- Total Pages
  4
- Publisher
  Elsevier, Amsterdam
- Data Source
  KAKENHI-PROJECT-14370277
[Book] Quantitation in Biomedical Imaging with PET and MRI, ICS1265.2004
- Author(s)
  Y.Kawata, T.Kamiya, H.Miura, A.Kimura, H.Fujiwara
- Total Pages
  4
- Publisher
  Elsevier, Amsterdam
- Data Source
  KAKENHI-PROJECT-14657215
[Journal Article] Regional fractional ventilation mapping in spontaneously breathing mice using hyperpolarized 129Xe MRI.2015
- Author(s)
  Imai H, Matsumoto H, Miyakoshi E, Okumura S, Fujiwara H, Kimura A.
- Journal Title
  
  NMR Biomed
  
  Volume: 28 Pages: 24-29
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-24300163
[Journal Article] Small animal imaging with hyperpolarized 129Xe magnetic resonance.2014
- Author(s)
  Imai H, Kimura A, Fujiwara H.
- Journal Title
  
  Anal Sci
  
  Volume: 30 Pages: 157-166
- NAID
  130004442237
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-24300163
[Journal Article] Validation of non-invasive morphological and diffusion imaging in mouse emphysema by micro-CT and hyperpolarized ^129Xe MRI2013
- Author(s)
  Satoshi Tetsumoto, Yoshioto Takeda, Hirohiko Imai, et al.
- Journal Title
  
  Am J Respir Cell Mol Biol
  
  Volume: 掲載決定 Issue: 4 Pages: 592-600
- DOI
  10.1165/rcmb.2012-0350oc
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23700534, KAKENHI-PROJECT-24300163, KAKENHI-PROJECT-25461386
[Journal Article] Direct Imaging of Alveolar Gas Uptake with Hyperpolarized 129xe Ultra-short Echo-Time MRI and Its Application to Physiological Assessment of Emphysema in Mouse Lung.2013
- Author(s)
  井口智史、木村敦臣
- Journal Title
  
  Magn. Reson. Med.
  
  Volume: in press Issue: 1 Pages: 592-600
- DOI
  10.1002/mrm.24452
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21500408, KAKENHI-PROJECT-23700534, KAKENHI-PROJECT-24300163
[Journal Article] MRS of Hypperpolarized ^<129>Xe in the Chest of Mouse - Effect of Contrast Agents on the MRS2004
- Author(s)
  M.Narazaki, T.Wakayama, A.Kimura, H.Fujiwara
- Journal Title
  
  International Congress Series 1265
  
  Pages: 177-180
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-14370277
[Journal Article] Hyperpolarized ^<129>Xe as a Novel Probe Agent of Lung Functions in MRI and MRS. Experimental Results with Mice at 9.4T2004
- Author(s)
  H.Fujiwara, A.Kimura, T.Wakayama
- Journal Title
  
  International Congress Series 1265
  
  Pages: 124-130
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-14370277
[Journal Article] MRS of Hyperpolarized ^<129>Xe in the Chest of Mouse -Effect of Contrast Agents on the MRS2004
- Author(s)
  M.Narazaki, T.Wakayama, A.Kimura, H.Fujiwara
- Journal Title
  
  International Congress Series 1265
  
  Pages: 177-180
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14370277
[Journal Article] Practical Application of NMR Spectra of ^<129>Xe dissolved in Red Blood Cell2004
- Author(s)
  Y.Kawata, T.Kamiya, H.Miura, A.Kimura, H.Fujiwara
- Journal Title
  
  International Congress Series 1265
  
  Pages: 172-176
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-14370277
[Journal Article] ^<19>F Magnetic Resonance Imaging of Perfluorooctanoic Acid Encapsulated in Liposome for Biodistribution Measurement2004
- Author(s)
  A.Kimura, M.Narazaki, Y.Kanazawa, H.Fujiwara
- Journal Title
  
  Mag.Reson.Imag. 22
  
  Pages: 855-860
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-14370277
[Journal Article] MRI and MRS of Mouse Head at 9.4T using Hyperpolarized Xenon Gas2004
- Author(s)
  T.Wakayama, T.Oose, M.Narazaki, A.Kimura, H.Fujiwara
- Journal Title
  
  International Congress Series 1265
  
  Pages: 167-171
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-14370277
[Journal Article] Improvement of T1 Determination of Hyperpolarized 129Xe in Mouse Brain under Controlled- Flow2004
- Author(s)
  A.Kimura, T.Wakayama, M.Narazaki, Y.Kawata, T.Ueyama, H.Fujiwara
- Journal Title
  
  International Congress Series 1265
  
  Pages: 199-205
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14370277
[Journal Article] Improvement of T1 Determination of Hyperpolarized 129Xe in Mouse Brain under Controlled-2004
- Author(s)
  A.Kimura, T.Wakayama, M.Narazaki, Y.Kawata, T.Ueyama, H.Fujiwara
- Journal Title
  
  International Congress Series 1265
  
  Pages: 199-205
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-14370277
[Journal Article] Analysis of the Effect of Foreign Gases in the Production of Hyperpolarized 129Xe Gas on a Simple System working under Atmospheric Pressure2003
- Author(s)
  J.Fukutani, E.Suzuki, T.Shimizu, A.Kimura, H.Fujiwara
- Journal Title
  
  J.magn.Reson. 160
  
  Pages: 26-32
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-14370277
[Journal Article] Analysis of the Effect of Foreign Gases in the Production of Hyperpolarized 129Xe Gas on a Simple System working under Atmospheric Pressure2003
- Author(s)
  J.Fukutomi, E.Suzuki, T.Shimizu, A.Kimura, H.Fujiwara
- Journal Title
  
  J.magn.Reson. 160
  
  Pages: 26-32
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14370277
[Presentation] Relationship between Brain and Pulmonary Function Studied by Hyperpolarized 129Xe MRI/MRS2016
- Author(s)
  Akihiro Shimkawa, Hironobu Matsumoto, Yukiko Yamauchi, Shota Hodono, Shintaro Okumura, Neil J Stewart, Hirohiko Imai, Hideaki Fujiwara, Atsuomi Kimura.
- Organizer
  1st AOWPFI & 8th JSPFI
- Place of Presentation
  Awaji Yumebutai International Conference Center、兵庫県(洲本市)
- Year and Date
  2016-01-30
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-24300163
[Presentation] Evaluation of Drug Efficacy of Ethyl Pyruvate on the Pulmonary fibrosis in mice with Hyperpolarized 129Xe MRI Pulmonary Functional Diagnosis2016
- Author(s)
  Shota Hodono, Akihiro Shimkawa, Hideaki Fujiwara, Hirohiko Imai, Atsuomi Kimura.
- Organizer
  1st AOWPFI & 8th JSPFI
- Place of Presentation
  Awaji Yumebutai International Conference Center、兵庫県(洲本市)
- Year and Date
  2016-01-31
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-24300163
[Presentation] 高沸点ガスのクエンチング効果による超偏極129Xe MRIの高感度化と応用2013
- Author(s)
  木村　敦臣, 河村　綾乃, 内山　知香, 奥村　慎太郎, 松本　浩伸, 山内　紬起子, 藤原　英明
- Organizer
  第52回NMR討論会
- Place of Presentation
  石川県立音楽堂
- Data Source
  KAKENHI-PROJECT-24300163
[Presentation] 高沸点ガスのクエンチ効果を用いた超偏極129Xe MRIの高感度化と応用
- Author(s)
  程野祥太、山内紬起子、萩原祐、細川尚武、藤原英明、木村敦臣
- Organizer
  第42回日本磁気共鳴医学会大会
- Place of Presentation
  ホテルグランヴィア京都（京都府京都市）
- Year and Date
  2014-09-18 – 2014-09-20
- Data Source
  KAKENHI-PROJECT-24300163
[Presentation] 超偏極129Xe MRI/MRSによる脳・肺機能連関に関する研究
- Author(s)
  山内紬起子、松本浩伸、程野祥太、萩原祐、細川尚武、藤原英明、木村敦臣
- Organizer
  第42回日本磁気共鳴医学会大会
- Place of Presentation
  ホテルグランヴィア京都（京都府京都市）
- Year and Date
  2014-09-18 – 2014-09-20
- Data Source
  KAKENHI-PROJECT-24300163

1. KIMURA Atsuomi (70303972)

# of Collaborated Projects: 5 results

# of Collaborated Products: 28 results
2. TAKAGI Tatsuya (80144517)

# of Collaborated Projects: 4 results

# of Collaborated Products: 0 results
3. BEPPU Shintaro (40113500)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
4. YAMATODANI Atsushi (30116123)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
5. MASUYAMA Toru (70273670)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. KOBAYASHI Kaoru (90256933)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. INOUE Osamu (50159969)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. ISHIKURA Fuminobu (50303970)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. MURASE Kenya (50157773)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. TAKEDA Yoshito (40452388)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. IMAI Hirohiko (40506466)

# of Collaborated Projects: 1 results

# of Collaborated Products: 7 results
12. 杉浦眞喜子 (00098500)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results

FUJIWARA Hideaki 藤原 英明

藤原 秀明 フジワラ ヒデアキ

Research Projects

Research Products

Co-Researchers

Development of preclinical system based on pulmonary functional imaging by hyperpolarized Xe MRI

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

簡易連続型超偏極希ガス生成装置の試作と水素や炭素核の高感度MRI実験への応用Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Applied Clinical Study on Hyperpolarized Noble Gas MRI/MRS using Pathologic Model AnimalPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

液晶NMR法におけるキラル液晶系の利用と天然分子の絶対構造決定の開発Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

超偏極希ガス簡易供給装置の開発と高感度磁気共鳴による脳機能計測の研究Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

磁気的な直接結合定数を利用した構造解析法の開発と微量天然物への応用展開研究Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Non-linear Analysis of Medical and Pharmaceutical Data using Neural Network and Generalized Additive Model

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Skill of intravenous ultrasonic contrast agent for evaluation of microcirculation of human organs and its assessment for clinical use.

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Improvement of Artificial Neural Networks and Its Applications to QSARs.

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

A Novel Agent for Contrast Echocardiography and its Evaluation in a Distinctive Clinical Application.

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

金属イオンの膜透過性を支配する天然超分子のNMRによる研究Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Institution

金属イオンの膜透過性を支配する天然超分子のNMRによる研究Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Institution

[Book] Hyperpolarized Xenon-129 Magnetic Resonance.2015

Author(s)

Total Pages

Publisher

Data Source

FUJIWARA Hideaki 藤原英明

藤原秀明フジワラヒデアキ