IIZUKA Hajime 飯塚一

Researcher Number	90113513
Other IDs
External Links
Affiliation (based on the past Project Information) *help	2009 – 2012: Asahikawa Medical College, 医学部, 教授 2002 – 2007: 旭川医科大学, 医学部, 教授 1988 – 1999: 旭川医科大学, 医学部, 教授
Review Section/Research Field	Principal Investigator Dermatology / Dermatology
Keywords	Principal Investigator 乾癬 / 角化 / keratinization / プロテインキナーゼC / involucrin / psoriasis / インボルクリン / protein kinase C / SERCA2b / ATP2A2 … More / calcium pump / Darier disease / カルシウムポンプ / ダリエー病 / loricrin / cornified cell envelope / AP-1 / 周辺帯 / ロリクリン / G蛋白質 / プロテインキナ-ゼC / アデニル酸ミクラ-ゼ / 表皮 / cyclic AMP / 表皮細胞 / Phospholipase C / Phorbol ester / Calcium / Protein kinase C / G protein / Adenylate cyclase / Psoriasis / TPA(tetradecanayl phonbol acetate) / tumor promoter / G蛋白質(guanine nucleotidl binding protein) / アデニル酸シクラーゼ / 尋常性乾癬 / ras / 癌遺伝子 / ホスホリパ-ゼC / ホルボ-ルエステル / カルシウム / プロティンキナ-ゼC / アデニル酸シクラ-ゼ / transgenic mouse / トランスジェニックマウス / 遺伝子導入マウス / endoplasmic reticulum / 小胞体 / granular layer / cystatin A / filaggrin / ケラトリニン / トランスグルタミナーゼ / フィラグリン / 顆粒層 / ロリフリン / シスタチンA / インボルフリン / turnover time / 周辺帯(cornified cell envelope) / プロティンキナーゼC / retinoid / 脱感作 / グルココルチコイド / βアドレナリン受容体 / プロテインキナーゼ / TPA / レチノイド / corneodesosin / corneodesmosin / podoplanin / Raf / STAT3 / MAP kinase / 乾癬表皮細胞 / IL-22 / ポドプラニン / 細胞内情報伝達 / 組織構築 / 表皮交代時間 Less

Cellular signaling system in Psoriatic epidermisPrincipal Investigator
- Principal Investigator
  
  IIZUKA Hajime
- Project Period (FY)
  2009 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Dermatology
- Research Institution
  Asahikawa Medical College
Analysis of Mutated SERCA2b transgenic mousePrincipal Investigator
- Principal Investigator
  
  IIZUKA Hajime
- Project Period (FY)
  2005 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Dermatology
- Research Institution
  Asahikawa Medical College
Kinetic propertie of three Darier disease SERCA26 mutants.Principal Investigator
- Principal Investigator
  
  IIZUKA Hajime
- Project Period (FY)
  2002 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Dermatology
- Research Institution
  Asahikawa Medical College
数理的解析モデルによる乾癬組織構築の定量化の研究Principal Investigator
- Principal Investigator
  
  飯塚一
- Project Period (FY)
  1998 – 1999
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Dermatology
- Research Institution
  Asahikawa Medical College
DISORGANIZED REGULATION OF CELL PROLIFERATION AND KERATINIZATION OF PSORIATIC EPIDERMIS : ANALYSIS OF DERANGED SIGNALING SYSTEM.Principal Investigator
- Principal Investigator
  
  IIZUKA Hajime
- Project Period (FY)
  1996 – 1998
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Dermatology
- Research Institution
  ASAHIKAWA MEDICAL COLLEGE
Cornified Cell Envelope Formation of Psoriatic KeratinocytesPrincipal Investigator
- Principal Investigator
  
  IIZUKA Hajime
- Project Period (FY)
  1994 – 1995
- Research Category
  
  Grant-in-Aid for General Scientific Research (B)
- Research Field
  
  Dermatology
- Research Institution
  Asahikawa Medical College
Transmembrane Signalling System in PsoriasisPrincipal Investigator
- Principal Investigator
  
  IIZUKA Hajime
- Project Period (FY)
  1991 – 1993
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Dermatology
- Research Institution
  Asahikawa Medical College
Transmembrane Signaling System in Psoriatic Keratinocytes.Principal Investigator
- Principal Investigator
  
  IIZUKA Hajime
- Project Period (FY)
  1988 – 1990
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Dermatology
- Research Institution
  Asahikawa Medical College

All 2013 2012 2011 2010 2009 2007 2006 2005 2004 2003 Other

All Journal Article Presentation

[Journal Article] Podoplanin expression is inversely correlated with granular layer/filaggrin formation in psoriatic epidermis.2013
- Author(s)
  Honma M, Fujii M, Iinuma S, Minami-Hori M, Takahashi H, Ishida-Yamamoto A., Iizuka H
- Journal Title
  
  J Dermatol
  
  Volume: 40 Pages: 296-7
- Data Source
  KAKENHI-PROJECT-21390323
[Journal Article] Podoplanin expression in wound and hyperproliferative psoriatic epidermis: Regulation by TGF-beta and STAT-3 activating cytokines2012
- Author(s)
  Honma M, Minami-Hori M, Takahashi H, Iizuka H
- Journal Title
  
  J Dermatol Sci
  
  Volume: 65 Pages: 134-140
- Data Source
  KAKENHI-PROJECT-21390323
[Journal Article] Tight junction-related multilayered network structures in mammalian epidermis.2012
- Author(s)
  Ishida-Yamamoto A, Kishibe M, Murakami M, Honma M, Takahashi H, Iizuka H.
- Journal Title
  
  PLoS ONE
  
  Volume: 7 Issue: 2 Pages: 1-7
- DOI
  10.1371/journal.pone.0031641
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23791246, KAKENHI-PROJECT-24591620, KAKENHI-PROJECT-21390323
[Journal Article] Podoplanin expression inwound and hyperproliferative psoriatic epidermis : Eegulation by TGF-β and STAT-3 activating cytokines2012
- Author(s)
  Honma, Minami-Hori, Takahashi, Iizuka
- Journal Title
  
  Journal of Dermatological Science
  
  Volume: 65 Pages: 134-140
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390323
[Journal Article] Lamellar granule secretion starts before the estqablishment of tight junction barrier for paracellular tracers in mammalian epidermis2012
- Author(s)
  Ishida-Yamamoto A, Kishibe M, Murakami M, Honma M, Takahashi H, Iizuka H
- Journal Title
  
  PloS One
  
  Volume: 7 Pages: 1-7
- Data Source
  KAKENHI-PROJECT-21390323
[Journal Article] Kallikrein-Related Peptidase 8.Dependent Skin Wound Healing Is Associated with Upregulation of Kallikrein-Related Peptidase 6 and PAR22012
- Author(s)
  Kishibe M, Bando Y, Tanaka T, Ishida-Yamamoto A, Iizuka H, Yoshida S
- Journal Title
  
  J Invest Dermatol
  
  Volume: 132 Pages: 1717-24
- Data Source
  KAKENHI-PROJECT-21390323
[Journal Article] Kallikrein-related peptidase 8-dependent skin wound healing is associated with upregulation of kallikrein-related peptidase 6 and PAR22012
- Author(s)
  Kishibe M, Bando Y, Tanaka T, Ishida-Yamamoto A, Iizuka H, Yoshida S
- Journal Title
  
  J Invest Dermatol
  
  Volume: (印刷中) Issue: 6 Pages: 1717-1724
- DOI
  10.1038/jid.2012.18
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21500322, KAKENHI-PROJECT-21791054, KAKENHI-PROJECT-24591620, KAKENHI-PROJECT-21390323
[Journal Article] Effects of serine palmitoyltransferase inhibitor ISP-1 on the stratum corneum of intact mouse skin2011
- Author(s)
  Mizukoshi K, Matsumoto K, Hirose R, Fujita T, Ishida-Yamamoto A, Iizuka H
- Journal Title
  
  Biol Pharm Bull
  
  Volume: 34 Pages: 1383-9
- Data Source
  KAKENHI-PROJECT-21390323
[Journal Article] Podoplanin expression in wound and hyperproliferative psoriatic epidermis : regulation by TGF-beta and STAT-3 activating cytokines, IFN-eanma, IL-6, and IL222011
- Author(s)
  Honma, Minami-Hori, Iizuka, et al
- Journal Title
  
  Journal of Investigative Der,atology
  
  Volume: (投稿中)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390323
[Journal Article] Management of patients with psoriasis in Japan2011
- Author(s)
  Iizuka H
- Journal Title
  
  Adv Psorisasis & Inflammatory skin diseases
  
  Pages: 126-132
- Data Source
  KAKENHI-PROJECT-21390323
[Journal Article] Analysis of psoriasis patients registered in Japanese Society for Psoriasis Research from 2002 to 20082011
- Author(s)
  Takahashi H, Nakamura K, Kaneko F, Nakagawa H, Iizuka H
- Journal Title
  
  J Dermatol
  
  Volume: 38 Pages: 1125-9
- Data Source
  KAKENHI-PROJECT-21390323
[Journal Article] Tight junctions in the stratum corneum explain spacial differences in corneodesmosome degradation.2010
- Author(s)
  Igawa, Kisibe, Ishida-Yamamoto, Iizuka, et al
- Journal Title
  
  Experimental Dermatology
  
  Volume: 20 Pages: 53-57
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390323
[Journal Article] Serum cytokines and growth factor levels in Japanese patients with psoriasis2010
- Author(s)
  Takahashi, Iizuka, et al
- Journal Title
  
  Clinical and Experimental Dermatology
  
  Volume: 35 Pages: 645-649
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390323
[Journal Article] Serum cytokines and growth factor levels in Japanese patients with psoriasis2010
- Author(s)
  Takahashi H, Tsuji H, Hashimoto Y, Ishida-Yamamoto A, Iizuka H
- Journal Title
  
  Clin Exp Dermatol
  
  Volume: 35 Pages: 645-9
- Data Source
  KAKENHI-PROJECT-21390323
[Journal Article]2010
- Author(s)
  Hajime Iizuka
- Journal Title
  
  Therapy of Skin Diseases 3.1 Psoriasis(Springer)
  
  Pages: 193-206
- Data Source
  KAKENHI-PROJECT-21390323
[Journal Article] Acrosyringium is the main site of the vesicle/pustule formation in palm oplantar pustulosis.2010
- Author(s)
  Murakami, Ishida-Yamamoto, Iizuka, et al
- Journal Title
  
  Journal of Investigative Dermatology (In press, on line publication)
- NAID
  120004606781
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390323
[Journal Article] Adiponectin and leptin modulate cell proliferation and cytokine secretion of normal human keratinocytes and T lymphocytes2010
- Author(s)
  Takahashi H, Honma M, Ishida-Yamamoto A, Iizuka H
- Journal Title
  
  J Dermatol Sci
  
  Volume: 59 Pages: 143-145
- NAID
  10027402055
- Data Source
  KAKENHI-PROJECT-21390323
[Journal Article] Tight junctions in the stratum corneum explain spacial differences in corneodesmosome degradation2010
- Author(s)
  Igawa S, Kishibe M, Murakami M Honma M, Takahashi H, Iizuka H, Ishida-Yamamoto A
- Journal Title
  
  Exp Dermatol
  
  Volume: 20 Pages: 53-57
- Data Source
  KAKENHI-PROJECT-21390323
[Journal Article] Prevalence of metabolic syndrome in Japanese psoriasis patients.2010
- Author(s)
  Takahashi, Honma, Iizuka, et al
- Journal Title
  
  Journal of Dermatolical Science 57
  
  Pages: 143-144
- NAID
  10027399756
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390323
[Journal Article] Prevalence of obesityadiposity in Japanese psoriasis patients ; adiposity is correlated with the severity of psoriasis.2009
- Author(s)
  Takahashi, Iizuka, et al
- Journal Title
  
  Journal of Dermatological Science 54
  
  Pages: 61-63
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390323
[Journal Article] Rab11 is associated with epidermal lamellar granules.2007
- Author(s)
  Ishida-Yamamoto. A, Kishibe M, Takahashi H, Iizuka H
- Journal Title
  
  127
  
  Pages: 2166-2170
- NAID
  120006658762
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17390309
[Journal Article] Congenital acantholytic dyskeratotic epidermal naevus followlng Blaschk-o's lines versus segmental Darier's disease.2007
- Author(s)
  Huh WK, Iizuka H, et. al.
- Journal Title
  
  Eur J Dermatol 17
  
  Pages: 130-132
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17390309
[Journal Article] Up-regulation of loricrinexpression by cell adhesion molecule nectin-l th-rough Rap-ERK signaling in keratinocytes.2007
- Author(s)
  Wakamatsu K, Iizuka H, et. al.
- Journal Title
  
  J BioI Chem 282
  
  Pages: 18173-81
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17390309
[Journal Article] Up-regulation of loricrin expression by cell adhesion molecule nectin-1 through Rap1-ERK signaling in keratinocytes.2007
- Author(s)
  Wakamatsu K, Iizuka H, et. al.
- Journal Title
  
  Journal of Biological Chemistry 282
  
  Pages: 18173-18181
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17390309
[Journal Article] Kallikrein 8 is involved in skin desquamation in corporation with other kallikreins.2007
- Author(s)
  Kishibe M, Bando Y, Terayama R, Namikawa K, Takahashi H, Hashimoto Y, Ishida-Yamamoto A, Jiang Y-P, Mitrovic B, Perez D, Iizuka H, Yoshida S
- Journal Title
  
  282
  
  Pages: 5834-5841
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17390309
[Journal Article] Recognition of prostate and melanoma tumor cells by six-transmembrane epithelial antigen of prostate specific helper T-lymphocytes in a human leukocyte antigen class II-restricted manner.2007
- Author(s)
  Kobayashi H, Iizuka H, et. al.
- Journal Title
  
  Cancer Research 67
  
  Pages: 5498-5504
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17390309
[Journal Article] Rabll is associated with epidermal lamellar granules.2007
- Author(s)
  Ishida-Yamamoto A, Iizuka H, et. al.
- Journal Title
  
  J Invest Dermatol 127
  
  Pages: 2166-2170
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17390309
[Journal Article] Kallikrein 8 is involved in skin desquamation in corporation with other kallikreins.2007
- Author(s)
  Kishibe M, Iizuka H, et. al.
- Journal Title
  
  J BioI Chem 282
  
  Pages: 5834-5841
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17390309
[Journal Article] Up-regulation of loricrinexpression by cell adhesion molecule nectin-1 through Rap-ERK signaling in keratinocytes.2007
- Author(s)
  Wakamatsu K, Ogita H, Okabe N, Irie K, Tanaka-Okamoto M, Ishizaki H, Ishida Yamamoto A, Iizuka H, Miyoshi J, Takai Y
- Journal Title
  
  282
  
  Pages: 18173-81
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17390309
[Journal Article] Kallikrein 8 is involved in skin desquamation in corporation with other kallikreins.2007
- Author(s)
  Kishibe, Yoshida, Bando, Takahashi, Iizuka, et al.
- Journal Title
  
  Journal of Biological Chemistry 282
  
  Pages: 5834-5841
- Data Source
  KAKENHI-PROJECT-17390309
[Journal Article] Cystatin A suppresses ultraviolet B-induced apoptosis of keratinocytes.2007
- Author(s)
  Takahashi H, Komatsu S, Ibe M, Ishida Yamamoto A, Hashimoto Y, Iizuka H
- Journal Title
  
  46
  
  Pages: 179-187
- NAID
  10024116292
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17390309
[Journal Article] Cystatin A suppresses ultraviolet Binduced apoptosis of keratino-cytes2007
- Author(s)
  Takahashi H, Iizuka H, et. al.
- Journal Title
  
  J Dermatol Sci 46
  
  Pages: 179-187
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17390309
[Journal Article] Comprehensive analysis of expression and function of 51 sarco (endo) plasmic reticulum Ca++ATPase mutants associated with Darier disease.2006
- Author(s)
  Miyauchi Y, Daiho T, Yamasaki K, Takahashi H, Ishida-Yamamoto A, Suzuki H, Iizuka H
- Journal Title
  
  281
  
  Pages: 22882-95
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17390309
[Journal Article] ATP2Cl is specifically localized in the basal layer of normal epidermis and its depletion triggers keratinocyte differ entiation2006
- Author(s)
  Yoshida M, Iizuka H, et. al.
- Journal Title
  
  J Dermatol Sci 43
  
  Pages: 21-33
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17390309
[Journal Article] Richner-Hanhart syndrome : report of a case with a novel mutation of tyrosine aminotransferase2006
- Author(s)
  Minami-Hori, Ishida-Yamamoto, Takahashi, Iizuka
- Journal Title
  
  Journal of Dermatological Science 41
  
  Pages: 82-84
- Data Source
  KAKENHI-PROJECT-17390309
[Journal Article] Richner - Hanhart syndrome : report of a case with a novel mutation of tyrosine aminotransferase2006
- Author(s)
  Minami-Hori, Ishida-Yamamoto, Takahashi H, Iizuka H
- Journal Title
  
  J Dermatol Science 41
  
  Pages: 82-84
- Data Source
  KAKENHI-PROJECT-17390309
[Journal Article] Comprehensive analysis of expression and function of 51 sarco (endo) plas-mic reticulum Ca++ATPase mutants associated with Darier disease.2006
- Author(s)
  Miyauchi Y, Iizuka H, et. al.
- Journal Title
  
  J BioI Chem 281
  
  Pages: 22882-95
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17390309
[Journal Article] LEKTI is localized in lamellar granules, separated from KLK5 and KLK7, and is secreted in the extracellular spaces of the superficial stratum granulosum.2005
- Author(s)
  Ishida-Yamamoto A, Deraison C, Bonnart C, Bitoun E, Robinson R, O'Brien TJ, Wakamatsu K, Ohtsubo S, Takahashi H, Hashinoto Y, Dopping-Hepenstal PJ, McGrath JA, Iizuka H, Richard G, Hovnanian A.
- Journal Title
  
  J Invest Dermatol 124
  
  Pages: 360-366
- NAID
  120003161707
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14370256
[Journal Article] LEKTI is localized in lamellar granules2005
- Author(s)
  Ishida-Yamamoto A, Iizuka H, et al.
- Journal Title
  
  Journal of Investigative Dermatology 124
  
  Pages: 360-366
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-14370256
[Journal Article] Prediction of a coding sequence for a novel type II keratin2005
- Author(s)
  Senshu T, Iizuka H, et al.
- Journal Title
  
  Journal of Dermatological Science 37
  
  Pages: 41-48
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-14370256
[Journal Article] Prediction of a coding sequence for a novel type II keratin from N-terminal sequences of mouse epidermal proteins site-specifically deminated in embryonic development2005
- Author(s)
  Senshu T, Iizuka H, et al.
- Journal Title
  
  Journal of Dermatological Science 37
  
  Pages: 41-48
- Data Source
  KAKENHI-PROJECT-14370256
[Journal Article] Prediction of a coding sequence for a novel type II keratin from N-terminal sequences of mouse epidermal proteins site-specifically deiminated in embryonic development.2005
- Author(s)
  Senshu T, Ishida-Yamamoto A, Takahashi H, Iizuka H.
- Journal Title
  
  J Dermatol Sci 37(1)
  
  Pages: 41-48
- NAID
  10018030387
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14370256
[Journal Article] Epidermal lamellar granules transport different cargoes2005
- Author(s)
  Ishida-Yamamoto A, Iizuka H, et al.
- Journal Title
  
  Journal of Investigative Dermatology 122
  
  Pages: 1137-1144
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-14370256
[Journal Article] LEKTI is localized in lamellar granules, separated from KLK5 and KLK7 and is secreted in the...2005
- Author(s)
  Ishida-Yamamoto A., Iizuka H et al.
- Journal Title
  
  J Invest Dermatol 124
  
  Pages: 360-366
- Data Source
  KAKENHI-PROJECT-17390309
[Journal Article] Prediction of a coding sequence of a novel typeII keratin from N-terminal sequence of mouse...2005
- Author(s)
  Senshu T, Ishida-Yamamoto, Takahashi H, Iizuka H
- Journal Title
  
  J Dermatol Science 37
  
  Pages: 41-48
- Data Source
  KAKENHI-PROJECT-17390309
[Journal Article] Photodynamic therapy using a novel photosensitizer, ATX-S10(Na)2005
- Author(s)
  Takahashi H, Ishida-Yamamoto, Iizuka H et al.
- Journal Title
  
  Arch Dermatol Research 296
  
  Pages: 496-502
- Data Source
  KAKENHI-PROJECT-17390309
[Journal Article] Plectin deficient epidermolysis bullosa simplex with 27-year-history of muscular dystrophy2005
- Author(s)
  Takahashi Y, Iizuka H, Ishida-Yamamoto et al.
- Journal Title
  
  J Dermatol Science 37
  
  Pages: 87-93
- NAID
  10017146892
- Data Source
  KAKENHI-PROJECT-17390309
[Journal Article] Roxithromycin suppresses involucrin expression by modulation of activator protein 1 and NFκB2005
- Author(s)
  Takahashi, Iizuka et al.
- Journal Title
  
  J Dermatol Science 39
  
  Pages: 175-182
- Data Source
  KAKENHI-PROJECT-17390309
[Journal Article] LEKTI Is Localized in Lamellar Granules, Separated from KLK5 and KLK7, and Is Secreted in the Extracellular Spaces of the Superficial Stratum Granulosum2005
- Author(s)
  Ishida-Yamamoto A, Deraison C, Iizuka H, et al.
- Journal Title
  
  Journal of Investigative Dermatology 124
  
  Pages: 360-366
- NAID
  120003161707
- Data Source
  KAKENHI-PROJECT-14370256
[Journal Article] Epidermal lamellar granules transport different cargoes as distinct aggregates.2004
- Author(s)
  Ishida-Yamamoto A, Simon M, Kishibe M, Miyauchi Y, Takahashi H, Yoshida S, O'Brien TJ, Serre G, Iizuka H.
- Journal Title
  
  J Invest Dermatol 122
  
  Pages: 1137-1144
- NAID
  120003161704
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14370256
[Journal Article] Effects of bepotastine, cetirizine, fexofenadine, and olopatadine on histamine-induced wheal-and flare-response, sedation, and psychomotor performance.2004
- Author(s)
  Takahashi H, Ishida-Yamamoto A, Iizuka H.
- Journal Title
  
  Clin Exp Dermatol 29
  
  Pages: 526-532
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14370256
[Journal Article] Unique keratinization process in psoriasis : late differentiation markers are abolished because of the premature cell death.2004
- Author(s)
  Iizuka H, Takahashi H, Honma M, Ishida-Yamamoto A.
- Journal Title
  
  J Dermatol 31
  
  Pages: 271-276
- NAID
  10016129386
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14370256
[Journal Article] Psoriatic architecture constructed by epidermal remodeling.2004
- Author(s)
  Iizuka H, Takahashi H, Ishida-Yamamoto A.
- Journal Title
  
  J Dermatol Sci 35
  
  Pages: 93-99
- NAID
  10016184480
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14370256
[Journal Article] Distinct types of abnormality in kinetic properties of three Darier disease2004
- Author(s)
  Sato K, Yamasaki K, Iizuka H, et al.
- Journal Title
  
  Journal of Biological Chemistry 279
  
  Pages: 35595-35603
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-14370256
[Journal Article] Psoriatic architecture constructed by epidermal remodeling2004
- Author(s)
  Iizuka H, Takahashi H, Ishida-Yamamoto A
- Journal Title
  
  Journal of Dermatological Science 35
  
  Pages: 93-99
- NAID
  10016184480
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-14370256
[Journal Article] Unique fertilization process in psoriasis2004
- Author(s)
  Iizuka H, Takahashi H, Honma N, Ishida-Yamamoto A
- Journal Title
  
  Journal of Dermatology 31
  
  Pages: 271-276
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-14370256
[Journal Article] Cyclic AMP differentially regulates cell proliferation of normal human keratinocytes through ERK activation depending on the expression pattern of B-Raf.2004
- Author(s)
  Takahashi H, Honma M, Miyauchi Y, Nakamura S, Ishida-Yamamoto A, Iizuka H.
- Journal Title
  
  Arch Dermatol Res 296
  
  Pages: 74-82
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14370256
[Journal Article] Unique keratinization process in psoriasts : late differentiation markers are abolished2004
- Author(s)
  Iizuka H, Takahashi H, Honma M, Ishida-Yamamoto A
- Journal Title
  
  Journal of Dermatology 31
  
  Pages: 271-276
- Data Source
  KAKENHI-PROJECT-14370256
[Journal Article] Distinct types of abnormality in kinetic properties of three Darier disease-causing sarco(endo)plasmic reticulum Ca2+-ATPase mutants that exhibit normal expression and high Ca2+ transport activity.2004
- Author(s)
  Sato K, Yamasaki K, Daiho T, Miyauchi Y, Takahashi H, Ishida-Yamamoto A, Nakamura S, Iizuka H, Suzuki H.
- Journal Title
  
  J Biol Chem 279
  
  Pages: 35595-35603
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14370256
[Journal Article] Distinct types of abnormality in kinetic properties of three Darier disease-causing Sarco(endo)plasmic Reticulum Ca^<2+>-ATPase Mutants That Exhibit Normal Expression and High Ca^<2+> Transport Activity2004
- Author(s)
  Sato K, Yamasaki K, Iizuka H, et al.
- Journal Title
  
  Journal of Biological Chemistry 279
  
  Pages: 35595-35603
- Data Source
  KAKENHI-PROJECT-14370256
[Journal Article] 1,25-dihydroxyvitamin D(3) increases human cystatin A expression by inhibiting the Raf-1/MEK1/ERK signaling pathway of keratinocytes.2003
- Author(s)
  Takahashi H, Ibe M, Honma M, Ishida-Yamamoto A, Hashinoto Y, Iizuka H.
- Journal Title
  
  Arch Dermatol Res 295
  
  Pages: 80-87
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14370256
[Journal Article] Activation of two caspase cascades, caspase 8/3/6 and caspase 9/3/6, during photodynamic therapy using a novel photosensitizer, ATX-S10(Na), in normal human keratinocytes.2003
- Author(s)
  Takahashi H, Itoh Y, Miyauchi Y, Nakajima S, Sakata I, Ishida-Yamamoto A, Iizuka H.
- Journal Title
  
  Arch Dermatol Res 295
  
  Pages: 242-248
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14370256
[Journal Article] SLURP-2, a novel member of the human Ly-6 superfamily that is uregulated in psoriasis vulgaris.2003
- Author(s)
  Tsuji h, Okamoto K, Matsuzaka Y, Iizuka H, Tamiya G, Inoko H
- Journal Title
  
  Genomics 81
  
  Pages: 26-33
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14370256
[Journal Article] Discoid lupus erythematosus exacerbated by radiation therapy.
- Author(s)
  Ishida-Yamamoto A, Kanno K, Sato E, Takahashi H, Iizuka H.
- Journal Title
  
  J Dermatol (in press)
- NAID
  10020272881
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14370256
[Presentation] A desquamation paradox of atopic dermatitis: markedly remaining corneodesmosomes despite the increased serine protease activity in vitro2012
- Author(s)
  Igawa S, Iimuma S, Kishibe M, Minami-Hori M, Honma M, Murakami M, Ishida-Yamamoto A, Iizuka H
- Organizer
  The 37^<th> annual meeting of the Japanese Society for Investigative Dermatology
- Data Source
  KAKENHI-PROJECT-21390323
[Presentation] Cell density-dependent induction of podoplanin through EGFR-STAT3 signaling pathway contributes to increased cell invasion of SCC cells2012
- Author(s)
  Fujii M, Honma M, Takahashi H, Ishida-Yamamoto A, Iizuka H
- Organizer
  The 37^<th> annual meeting of the Japanese Society for Investigative Dermatology
- Data Source
  KAKENHI-PROJECT-21390323
[Presentation] 乾癬の治療：生物学製剤の時代におけるピラミッド計画2012
- Author(s)
  飯塚　一
- Organizer
  第２７回日本乾癬学会学術大会
- Place of Presentation
  新潟市　朱鷺メッセ
- Invited
- Data Source
  KAKENHI-PROJECT-21390323
[Presentation] Podoplanin alters beta1-integrin-mediated cell adhesion and initiates terminal differentiation in human epidermal keratinocytes2012
- Author(s)
  Honma M, Fujii M, Takahashi H, Iizuka H
- Organizer
  The 37^<th> annual meetiThe 37th annual meeting of the Japanese Society for Investigative Dermatology
- Data Source
  KAKENHI-PROJECT-21390323
[Presentation] Epidermal lamellar granule secretion starts before establishment of paracellular permeability barrier2011
- Author(s)
  Ishida-Yamamoto A, Kishibe M, Murakami M, Iizuka H
- Organizer
  The 36^<th> annual meeting of the Japanese Society for Investigative Dermatology
- Data Source
  KAKENHI-PROJECT-21390323
[Presentation] Podoplanin induces upregulated cell mortility through activation of coffilin and matrix metalloproteinase-9 in HaCat cells2011
- Author(s)
  Fujii M, Honma M, Takahashi H, Ishida-Yamamoto A, Iizuka H
- Organizer
  The 36^<th> annual meeting of the Japanese Society for Investigative Dermatology
- Data Source
  KAKENHI-PROJECT-21390323
[Presentation] Kallikrein-related peptidase 8 is involved in skin wound healing the rough upregulation of KLK6 and protease activated receptor 22011
- Author(s)
  Kishibe M, Igawa S, Ishida-Yamamoto A, Iizuka H
- Organizer
  The 36^<th> annual meeting of the Japanese Society for Investigative Dermatology
- Data Source
  KAKENHI-PROJECT-21390323
[Presentation] 乾癬表皮における組織構築の変動と角化異常の再評価2011
- Author(s)
  飯塚一
- Organizer
  第26回日本乾癬学会学術大会
- Place of Presentation
  大阪国際会議場(特別(招待)講演)
- Year and Date
  2011-09-09
- Data Source
  KAKENHI-PROJECT-21390323
[Presentation] Podoplanin upregulates cell mortility through the activation of cofilin and matrix metalloproteinase in immortalized epidermal keratinocytes2010
- Author(s)
  Honma M, Fujii M, Iizuka H
- Organizer
  The 35^<th> annual meeting of the Japanese Society for Investigative Dermatology
- Data Source
  KAKENHI-PROJECT-21390323
[Presentation] Adiponectin and leptin modulte cell proliferation and cytokine expressions of normal human keratinocytes and T lymphocytes2010
- Author(s)
  Takahashi H, Tsuji H, Iizuka H
- Organizer
  The 35^<th> annual meeting of the Japanese Society for Investigative Dermatology
- Data Source
  KAKENHI-PROJECT-21390323
[Presentation] Tight junctions in the stratum crneum explain special differences in corneodesmosome degradation2010
- Author(s)
  Ishida-Yamamoto A, Igawa S, Kishibe M, Murakami M, Honma M, Iizuka H
- Organizer
  The 35th annual meeting of the Japanese Society for Investigative Dermatology
- Data Source
  KAKENHI-PROJECT-21390323
[Presentation] A new era of the pathophysiology of psoriasis: anti-TNF-alfa agents as a smart bomb with multiple targets2010
- Author(s)
  Iizuka H
- Organizer
  The 35^<th> annual meeting of the Japanese Society for Investigative Dermatology
- Data Source
  KAKENHI-PROJECT-21390323
[Presentation] TIP-DC-Th17細胞学説からみた乾癬の病態と治療2009
- Author(s)
  飯塚一
- Organizer
  第60回日本皮膚科学会中部支部学術大会:特別講演
- Place of Presentation
  国立京都国際会館
- Year and Date
  2009-10-10
- Data Source
  KAKENHI-PROJECT-21390323

1. TAKAHASHI Hiswtoshi (00216748)

# of Collaborated Projects: 7 results

# of Collaborated Products: 41 results
2. YAMAMOTO Akemi (30241441)

# of Collaborated Projects: 6 results

# of Collaborated Products: 44 results
3. TSUTSUI Masato (10172032)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
4. HONMA Masaru (50344578)

# of Collaborated Projects: 1 results

# of Collaborated Products: 15 results
5. HASHIMOTO Yoshio (70172880)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. NAKAMURA Satoshi (20292112)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
7. 梶田哲 (20152647)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. 板東良雄

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
9. 吉田成孝

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

IIZUKA Hajime 飯塚 一

Research Projects

Research Products

Co-Researchers

Cellular signaling system in Psoriatic epidermisPrincipal Investigator

Principal Investigator

Project Period (FY)

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Research Institution

Analysis of Mutated SERCA2b transgenic mousePrincipal Investigator

Principal Investigator

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Kinetic propertie of three Darier disease SERCA26 mutants.Principal Investigator

Principal Investigator

Project Period (FY)

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Research Institution

数理的解析モデルによる乾癬組織構築の定量化の研究Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

DISORGANIZED REGULATION OF CELL PROLIFERATION AND KERATINIZATION OF PSORIATIC EPIDERMIS : ANALYSIS OF DERANGED SIGNALING SYSTEM.Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Cornified Cell Envelope Formation of Psoriatic KeratinocytesPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

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Research Institution

Transmembrane Signalling System in PsoriasisPrincipal Investigator

Principal Investigator

Project Period (FY)

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Research Field

Research Institution

Transmembrane Signaling System in Psoriatic Keratinocytes.Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Podoplanin expression is inversely correlated with granular layer/filaggrin formation in psoriatic epidermis.2013

Author(s)

Journal Title

Data Source

[Journal Article] Podoplanin expression in wound and hyperproliferative psoriatic epidermis: Regulation by TGF-beta and STAT-3 activating cytokines2012

Author(s)

Journal Title

Data Source

[Journal Article] Tight junction-related multilayered network structures in mammalian epidermis.2012

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Podoplanin expression inwound and hyperproliferative psoriatic epidermis : Eegulation by TGF-β and STAT-3 activating cytokines2012

Author(s)

Journal Title

Data Source

[Journal Article] Lamellar granule secretion starts before the estqablishment of tight junction barrier for paracellular tracers in mammalian epidermis2012

Author(s)

Journal Title

Data Source

[Journal Article] Kallikrein-Related Peptidase 8.Dependent Skin Wound Healing Is Associated with Upregulation of Kallikrein-Related Peptidase 6 and PAR22012

Author(s)

Journal Title

Data Source

[Journal Article] Kallikrein-related peptidase 8-dependent skin wound healing is associated with upregulation of kallikrein-related peptidase 6 and PAR22012

Author(s)

Journal Title

IIZUKA Hajime 飯塚一