WATAYA Yusuke 綿矢有佑

… Alternative Names

Researcher Number	90127598
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Affiliation (based on the past Project Information) *help	2013: 岡山大学, 医歯(薬)学総合研究科, 教授 2012: 岡山大学, 医歯(薬)学総合研究科, 名誉教授 2012: 岡山大学, 大学院・医歯薬学総合研究科, 名誉教授 2011: 岡山大学, 医歯(薬)学総合研究科, 教授 2010 – 2011: 岡山大学, 大学院・医歯薬学総合研究科, 教授 … More
Review Section/Research Field	Principal Investigator Biological pharmacy / Biological Sciences / Drug development chemistry / Environmental pharmacy / Parasitology (including Sanitary zoology) / Medical pharmacy / 寄生虫学(含医用動物学） / 寄生虫学(含医用動物学) / Chemical pharmacy Except Principal Investigator Biological pharmacy … More
Keywords	Principal Investigator 細胞死 / マラリア / DNA二本鎖切断 / エンドヌクレアーゼ / 化学療法剤 / アポトーシス / PCR / 熱帯熱マラリア / Malaria / 不均衡 … More Except Principal Investigator マラリア / Trp-P-2 / DNA鎖切断 / Malaria / 突然変異 / 活性酸素 / 染色体異常 / ヌクレオシド / 代謝拮抗剤 / アポトーシス / 熱帯熱マラリア / チミジル酸ストレス / 細胞周期 / genotoxicity / DNA組換え / クロロフィル / 温度感受性変異株 / 遺伝子損傷 / 修復酵素 / 生体高分子 / レチノイド / ネオカルチノスタチン / サイクリックADPリボース / クロロフィリン / HITECマウス / Plasmodium / ワクチン / 細胞内DNA / ショウジョウバエ / PCR / malaria / 新型変異株 / LC / NMR-LC / MS / isoquinoline alkaloids / 新規抗マラリア薬 / 環状過酸化化合物 / 薬剤耐性 / ELISA / 温度感受性変異 / H1ヒストン / 蛋白質のリン酸化 / 蛋白質の脱リン酸化 / 染色体凝縮 / Trp-P-2(NHOH) / λファ-ジ / キイロショウジョウバエ / クロロフィリン誘導体 / ユビキチン活性化酵素 / トポイソメラ-ゼ / ヒストンH1キナ-ゼ / リン酸化 / 原虫 / リーシュマニア / ヌクレオシド・アナログ / リポリーム / イノシンアナログ / マクロファージ / 駆虫薬 / SDDS / リ-シュマニア / ヌクレオシドアナログ / リポソ-ム / マクロファ-ジ / ヌクレオチド / シアノ基 / AIDS / HIV / DNAポリメラ-ゼ / 寄生原虫 / オリゴヌクレオチド / 光酸化反応 / ヌクレアーゼ / 逆転写酵素 / 核酸代謝 / ハリコンンドリンB / タキリ-ル / rpsL / 大腸菌 / DNAアダクト / 変異スペクトラム / ハリコンドリンB / タキソ-ル / rpsL遺伝子 / 太陽光 / キトサン / 食品 / 植物成分 / 抗がん剤 / カスパーゼ / p53 / RNA合成阻害剤 / ドラッグデザイン / 血管新生 / エンジイン / 遺伝子 / 抗マラリア薬 / マラリア伝播 / 生態系 / 免疫 / N-OH-Trp-P-2 / N-OH-Glu-P-1 / MeIQx / 青綿 / ヒト排泄物中変異原 / ヘテロサイクリックアミン / DNA切断 / 姉妹染色分体交換 / ヌクレオチドプール不均衡とDNA切断 / O^6-メチルグアニンと突然変異 / DNAトポイソメラーゼ / カンプトテシン / DNA高次構造 / 遺伝子発現制御 / Trp-P-2(NHOH)、クロロフィル / プロファージ誘発 / FM3A細胞 / λファージ / catalase-enriched FM3A細胞 / DNAクロスリンク / 蛍光分析 / ニトロソアミン / 8ーメトキシソラレン / 近紫外光 / 蛍光光度分析 / DNAー本鎖切断 / 光 / 遺伝子損傷阻害物質 / フォスゲン / 螢光分析法 / fluorometry / DNA damage / N-nitrosamines / 8-methoxypsoralen / light / ソロモン諸島 / ハマダラカ / 血液検査 / DNA診断 / 超音波診断 / G6PD欠損 / ソロモン / 血清診断 / G6PD / 酵素欠損 / Solomon Islands / Anopheles acridine orange / DNA diagnosis / ultrasonic diagnosis / mosquito fish / ベトナム / 迅速診断法 / 遺伝子診断法 / ウイルス性下痢症 / ロタウイルス / エンテロウイルス / 小児感染症 / 新型マラリア原虫 / 卵形マラリア / 下痢症ウイルス / Vietnam / Rapid diagnosis / PCR diagnosis / New variant form / Viral diarrhea / Rotavirus / Enterovirus / 遺伝子診断 / アクリジンオレンジ染色 / タイ / インドネシア / 中国 / ミャンマー / 分子疫学 / 四日熱マラリア / リボゾームRNA遺伝子 / Molecular diagnosis / Acridine orange staining / New variant / Thailand / Indonesia / Myanmar / China / 化学療法剤 / 新興・再興感染症 / 宿主・寄生体相互作用 / 熱帯感染症 / 寄生適応 / 新薬開発 / 免疫応答 / 実験動物モデル / ベクター / Tropical infectious diseases / Parasitic adaptation / vaccine / drug developmen / immunoresponse / animal model / vector / 常山 / アルカロイド / フェブリフジン / 抗マラリア作用 / 甘松香 / テルペノイド / Dichroa febrifuga / Alkaloid / Febrifugine / Antimalarial activity / イソキノリンアルカロイド / 生物活性 / 構造活性相関 / 植物組織培養 / 代謝物 / 生物学的変換 / 構造解析 / イソキノリンアルカロイド / 抗酸化活性 / 発がんプロモーション抑制活性 / 構造-活性相関 / 植物組織培養細胞 / 代謝物の構造解析 / antimalarial activity / antitumor activity / antiHIV activity / antimicrobial activity / structure-activity relationships / biological activity / structure-activity relationship / plant tissue cultures / metabolites / biotransformation / structural analysis / 薬剤耐性マラリア / 環状過酸化物 / 薬剤耐性熱帯熱マラリア / シクロアルカン系 / アシクロアルカン系 / Drug-resistant / Endoperoxides / New antimalarials / hemoglobin degradation / protease inhibitor / 耐性機構 / 作用機序解析 / 天然生薬抗マラリア資源 / 薬剤耐性メカニズム / endoperoxides / drug-resistant / antimalarials / johzan alkaloid / mechanism analysis / 試験管内突然変異 / N^4-アミノシチジン / N^4-アミノdCTP / M13ファージ / 塩基置換 / トランジション変異 / 複製 / 【N^4】ーアミノシチジン / 【N^4】ーアミノデオキシシチジン / 変異原性 / 複製エラー / ONAシークエンス / 金属イオン / N^4-Aminocytidine / transition mutation / replication error / M13mp2,FM3A cell / V79 cell / ピリメサミン / 倍養 / 培養 / 電気泳動 / OFAGE / 抗マラリア剤 / Pyrimethamine / Drug resistance Less

経皮吸収型抗マラリア薬開発のための基礎研究Principal Investigator
- Principal Investigator
  
  綿矢有佑
- Project Period (FY)
  2013
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Medical pharmacy
- Research Institution
  Okayama University
Study of novel anti-leishmanial drugPrincipal Investigator
- Principal Investigator
  
  WATAYA Yusuke
- Project Period (FY)
  2011 – 2012
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Parasitology (including Sanitary zoology)
- Research Institution
  Okayama University
Study of new broad spectrum of anti-parasitic agent and basis of molecular base of itPrincipal Investigator
- Principal Investigator
  
  WATAYA Yusuke
- Project Period (FY)
  2010 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Environmental pharmacy
- Research Institution
  Okayama University
広範囲抗寄生虫薬の開発のための標的治療の分子基盤の確立Principal Investigator
- Principal Investigator
  
  綿矢有佑
- Project Period (FY)
  2007 – 2008
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Okayama University
慢性疲労症候群診断法の開発と発症因子の探索Principal Investigator
- Principal Investigator
  
  綿矢有佑
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Drug development chemistry
- Research Institution
  Okayama University
New antiamlarial drug development research against drug-resistant Plasmodium falciparum
- Principal Investigator
  
  KIM Hyesook
- Project Period (FY)
  2004 – 2005
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Drug development chemistry
- Research Institution
  OKAYAMA UNIVERSITY
New antiamlarial drug development research including mechanism analysis of drug-resistant Plasmodium falciparumPrincipal Investigator
- Principal Investigator
  
  WATAYA Yusuke
- Project Period (FY)
  2002 – 2005
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  OKAYAMA UNIVERSITY
RNA合成阻害を作用機序とする新規抗腫瘍薬3'-エチニルシチジンの分子標的の探索Principal Investigator
- Principal Investigator
  
  綿矢有佑
- Project Period (FY)
  2001
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (C)
- Review Section
  
  Biological Sciences
- Research Institution
  Okayama University
新しい抗マラリア薬の開発と抗マラリア薬耐性機構の解析に関する研究Principal Investigator
- Principal Investigator
  
  綿矢有佑
- Project Period (FY)
  2001
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (C)
- Review Section
  
  Biological Sciences
- Research Institution
  Okayama University
Development of new antimalarial endoperoxides and it's antimalarial mechanism
- Principal Investigator
  
  KIM Hye-sook
- Project Period (FY)
  2001 – 2002
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Biological pharmacy
- Research Institution
  OKAYAMA UNIVERSITY
New Antimalarial Drug Research for Multidrug-resistant MalariaPrincipal Investigator
- Principal Investigator
  
  WATAYA Yusuke
- Project Period (FY)
  2000 – 2002
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  寄生虫学(含医用動物学)
- Research Institution
  Okayama University
Development of Novel Antimalarial Drugs Based on Plant Alkaloids
- Principal Investigator
  
  OSHIMA Yoshiteru
- Project Period (FY)
  2000 – 2001
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Chemical pharmacy
- Research Institution
  Tohoku University
Study on Biological Activity of Isoquinoline-Type Alkaloids
- Principal Investigator
  
  IWASA Kuniko
- Project Period (FY)
  2000 – 2002
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Chemical pharmacy
- Research Institution
  Kobe Pharmaceutical University
ドラッグデザインによる新しい抗がん剤の合成
- Principal Investigator
  
  松田彰
- Project Period (FY)
  1999
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (A)
- Research Institution
  Hokkaido University
マラリア制圧の総合戦略
- Principal Investigator
  
  TANABE Kazuyuki
- Project Period (FY)
  1999
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  寄生虫学(含医用動物学)
- Research Institution
  Osaka Institute of Technology
Development of simple and specific DNA diagnostic method of Malaria in Malaria endemic areasPrincipal Investigator
- Principal Investigator
  
  WATAYA Yusuke
- Project Period (FY)
  1999 – 2001
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Biological pharmacy
- Research Institution
  OKAYAMA UNIVERSITY
トランスジェニックマウスを用いた,発がん物質による遺伝子損傷とその抑制の解析
- Principal Investigator
  
  根岸和雄
- Project Period (FY)
  1997
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Okayama University
トランスジェニックマウスを用いた、発がん物質による遺伝子損傷とその抑制の解析
- Principal Investigator
  
  根岸和雄
- Project Period (FY)
  1996
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Okayama University
生体高分子機能を修飾する抗がん化合物の合成と作用解析
- Principal Investigator
  
  松田彰
- Project Period (FY)
  1996
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Hokkaido University
Molecular approach for malaria control
- Principal Investigator
  
  KITA Kiyoshi, 小島荘明 (小島莊明)
- Project Period (FY)
  1996 – 2000
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (A)
- Research Institution
  The University of Tokyo
Development of Anti-malarial Drug and it's Molecular TargetPrincipal Investigator
- Principal Investigator
  
  WATAYA Yusuke
- Project Period (FY)
  1996 – 1999
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (A)
- Research Institution
  Okayama University
Study of the molecular mechanisms of cell death induced by the dNTP pool imbalance.Principal Investigator
- Principal Investigator
  
  WATAYA Yusuke
- Project Period (FY)
  1996 – 1997
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Biological pharmacy
- Research Institution
  Okayama University
生体高分子機能を修飾する抗がん化合物の合成と作用解析
- Principal Investigator
  
  松田彰
- Project Period (FY)
  1995
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Hokkaido University
細胞死を引き起こすDNA二本鎖切断酵素遺伝子を標的とする化学療法剤の開発Principal Investigator
- Principal Investigator
  
  綿矢有佑
- Project Period (FY)
  1995
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Okayama University
Surveys on new human malaria in South East Asia
- Principal Investigator
  
  KAWAMOTO Fumihiko
- Project Period (FY)
  1995 – 1996
- Research Category
  
  Grant-in-Aid for international Scientific Research
- Research Institution
  Nagoya University School of medicine
Development of a new DNA diagnostic system for the species-specific detection of human malaria parasites using specific nucleotide sequences of the 18S ribosomal RNA gene.Principal Investigator
- Principal Investigator
  
  WATAYA Yusuke
- Project Period (FY)
  1995 – 1997
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Biological pharmacy
- Research Institution
  Okayama University
細胞死を引き起こすDNA二本鎖切断酵素遺伝子を標的とする化学療法剤の開発Principal Investigator
- Principal Investigator
  
  綿矢有佑
- Project Period (FY)
  1994
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Okayama University
Surveys on malaria and enteroviruses in Vietnamese children
- Principal Investigator
  
  ISOMURA Shin
- Project Period (FY)
  1994 – 1995
- Research Category
  
  Grant-in-Aid for international Scientific Research
- Research Institution
  Nagoya University
機能の創生を目指すヌクレオシドの化学合成
- Principal Investigator
  
  松田彰
- Project Period (FY)
  1993
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Hokkaido University
遺伝子損傷と突然変異の分子基盤
- Principal Investigator
  
  早津彦哉
- Project Period (FY)
  1993
- Research Category
  
  Grant-in-Aid for Co-operative Research (B)
- Research Field
  
  Biological pharmacy
- Research Institution
  Okayama University
dNTP Imbalance and DNA Double Strand Breaks in Mouse FM3A Cells and the Mechanism of Cell DeathPrincipal Investigator
- Principal Investigator
  
  WATAYA Yusuke
- Project Period (FY)
  1993 – 1994
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Biological pharmacy
- Research Institution
  Okayama University
遺伝子損傷と突然変異の分子基盤
- Principal Investigator
  
  早津彦哉
- Project Period (FY)
  1992
- Research Category
  
  Grant-in-Aid for Co-operative Research (B)
- Research Field
  
  Biological pharmacy
- Research Institution
  Okayama University
機能の創生を目指すヌクレオシドの化学合成
- Principal Investigator
  
  松田彰
- Project Period (FY)
  1991
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Hokkaido University
Studies on epidemiology and control of malaria in the Solomon Islands
- Principal Investigator
  
  SASA Manabu
- Project Period (FY)
  1991 – 1993
- Research Category
  
  Grant-in-Aid for international Scientific Research
- Research Institution
  Toyama Univ. of International Studies
DNA Diagnosis of Malaria Using PCR Techniques.Principal Investigator
- Principal Investigator
  
  WATAYA Yusuke
- Project Period (FY)
  1991 – 1992
- Research Category
  
  Grant-in-Aid for Developmental Scientific Research (B)
- Research Field
  
  寄生虫学(含医用動物学）
- Research Institution
  Okayama University
dNTP Pool Imbalance Induced Endonuclease : Mechanism of All Death.Principal Investigator
- Principal Investigator
  
  WATAYA Yusuke
- Project Period (FY)
  1991 – 1992
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Biological pharmacy
- Research Institution
  Okayama University
がん細胞における染色体の不安定化と再配列に関与する分子遺伝学的研究
- Principal Investigator
  
  瀬野捍二
- Project Period (FY)
  1990
- Research Category
  
  Grant-in-Aid for Cancer Research
- Research Institution
  National Institute of Genetics
リポリームなどDDSの工夫を加えたヌクレオシド系抗寄生原虫剤の開発研究
- Principal Investigator
  
  ISHII Akira
- Project Period (FY)
  1990 – 1992
- Research Category
  
  Grant-in-Aid for Developmental Scientific Research (B)
- Research Field
  
  寄生虫学(含医用動物学）
- Research Institution
  国立予防衛生研究所
デオキシヌクレオシドミリン酸プ-ルの不均衡が誘導するDNA二本鎖切断酵素の解析Principal Investigator
- Principal Investigator
  
  綿矢有佑
- Project Period (FY)
  1989
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Biological pharmacy
- Research Institution
  Okayama University
発がん性ヘテロサイクリックアミンによる遺伝子損傷とその修飾
- Principal Investigator
  
  早津彦哉
- Project Period (FY)
  1989
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Okayama University
Studies on DNA damages in vivo and in vitro by highly sensitive fluorometric analysis
- Principal Investigator
  
  HAYATSU Hikoya
- Project Period (FY)
  1989 – 1991
- Research Category
  
  Grant-in-Aid for international Scientific Research
- Research Institution
  Okayama University
がん細胞における染色体の不安定化と再配列に関与する因子の分子遺伝学的研究
- Principal Investigator
  
  瀬野悍二
- Project Period (FY)
  1988 – 1990
- Research Category
  
  Grant-in-Aid for Cancer Research
- Research Institution
  National Institute of Genetics
がん細胞における染色体の不安定化と再配列に関与する因子の分子遺伝学的研究
- Principal Investigator
  
  瀬野悍二
- Project Period (FY)
  1988
- Research Category
  
  Grant-in-Aid for Cancer Research
- Research Institution
  National Institute of Genetics
発がん性ヘテロサイクリックアミンによる遺伝子損傷とその修飾
- Principal Investigator
  
  早津彦哉
- Project Period (FY)
  1988
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Okayama University
発がん性ヘテロサイクリックアミンによる遺伝子損傷とその修飾
- Principal Investigator
  
  早津彦哉
- Project Period (FY)
  1987
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Okayama University
抗アラリア剤ピリメサミンの標的酵素遺伝子のクローニングとその薬剤耐性機構の解明
- Principal Investigator
  
  ISHII Akira
- Project Period (FY)
  1987 – 1988
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  寄生虫学(含医用動物学）
- Research Institution
  Okayama University Medical School
Deoxyribonucleoside Triphosphate Imbalance: The Mechanism of Cell Death and DNA-Double Strand Breaks.Principal Investigator
- Principal Investigator
  
  WATAYA Yusuke
- Project Period (FY)
  1987 – 1988
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Biological pharmacy
- Research Institution
  Okayama University, Faculty of Pharmaceutical Sciences
食品の加熱で生ずる発癌物質の遺伝子損傷作用とその促進・抑制に関する研究
- Principal Investigator
  
  早津彦哉
- Project Period (FY)
  1986
- Research Category
  
  Grant-in-Aid for Special Project Research
- Research Institution
  Okayama University
Base changes in the replication of DNA induced by nucleotide analogs and the use for in vitro mutagenesis
- Principal Investigator
  
  HAYATSU Hikoya
- Project Period (FY)
  1986 – 1987
- Research Category
  
  Grant-in-Aid for General Scientific Research (B)
- Research Field
  
  Biological pharmacy
- Research Institution
  Okayama University
Anti-Parasitic Activity of Nucleoside Analogues against Leishmania tropica and Leishmania donovani.Principal Investigator
- Principal Investigator
  
  WATAYA Yusuke
- Project Period (FY)
  1986 – 1987
- Research Category
  
  Grant-in-Aid for Developmental Scientific Research
- Research Field
  
  Chemical pharmacy
- Research Institution
  Okayama University, Faculty of Pharmaceutical Sciences

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All Journal Article Presentation Book Patent

[Book] 最新医学「感染症医薬品開発の現状」薬剤耐性マラリアに対する新規治療薬開発の現状2012
- Author(s)
  金惠淑、佐藤聡、森田将之、綿矢有佑
- Publisher
  最新医学社
- Data Source
  KAKENHI-PROJECT-22390024
[Book] 薬剤耐性マラリアに対する新規治療薬開発の現況。最新医学、67 (11)2012
- Author(s)
  金惠淑、佐藤聡、森田将之、綿矢有佑
- Data Source
  KAKENHI-PROJECT-22390024
[Book] 最新医学「感染症医薬品開発の現状」薬剤耐性マラリアに対する新規治療薬開発の現状2012
- Author(s)
  金惠淑、佐藤聡、森田将之、綿矢有佑
- Publisher
  最新医学社
- Data Source
  KAKENHI-PROJECT-23659212
[Book] 核膜の裏打ちタンパク質Lamin-B1。生体の科学, Vol.62 (5)2011
- Author(s)
  佐藤聡、金惠淑、綿矢有佑
- Data Source
  KAKENHI-PROJECT-22390024
[Book] 実験医学2005
- Author(s)
  綿矢有佑, 金惠淑
- Total Pages
  5
- Data Source
  KAKENHI-PROJECT-16390031
[Book] 実験医学2005
- Author(s)
  綿矢有佑, 金惠淑
- Total Pages
  5
- Publisher
  抗マラリヤ薬の開発 : 過去-現在-未来
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16390031
[Book] 実験医学2005
- Author(s)
  綿矢有佑, 金恵淑
- Total Pages
  5
- Publisher
  抗マラリア薬の開発 : 過去-現在-未来
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-14021072
[Book] 実験医学 5.抗マラリア薬の開発:過去-現在-未来2005
- Author(s)
  綿矢有佑, 金惠淑
- Total Pages
  5
- Data Source
  KAKENHI-PROJECT-14021072
[Book] 抗原虫薬2004
- Author(s)
  金恵淑, 綿矢有佑, 木村幹男, 益山新樹, 野島正朋
- Total Pages
  5
- Publisher
  臨床と微生物
- Data Source
  KAKENHI-PROJECT-16390031
[Book] 抗原虫薬2004
- Author(s)
  金惠淑, 綿矢有佑, 木村幹男, 益山新樹, 野島正朋
- Total Pages
  5
- Publisher
  臨床と微生物
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16390031
[Journal Article] Applications of triphenylpyrylium salt-sensitized electron transfer photo-oxygenation reactions to the synthesis of benzo-fused 1,4-diaryl-2,3- dioxabicyclo[2.2.2]octanes as new antimalarial cyclic peroxides.2013
- Author(s)
  Kamata, M., Hagiwara, J., Hokari,T., Suzuki,C., Fujino,R., Kobayashi,S., Kim,H.-S.and Wataya, Y
- Journal Title
  
  Research on Chemical Intermediate
  
  Volume: 39 Pages: 127-137
- URL
  http://link.springer.com/article/10.1007/s11164-012-0637-3
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22390024
[Journal Article] Andirolides HeP from the flower of andiroba (Carapa guianensis, Meliaceae)2012
- Author(s)
  Tanaka Y, Sakamoto A, Inoue T, Yamada T, Kikuchi T, Kajimoto T, Muraoka O, Sato A, Wataya Y, Kim H.-S, and Tanaka R.
- Journal Title
  
  Tetrahedron
  
  Volume: 68 Pages: 3669-77
- URL
  http://www.sciencedirect.com/science/article/pii/S0040402011019727
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23659212
[Journal Article] Andirolides HeP from the flower of andiroba (Carapa guianensis, Meliaceae).2012
- Author(s)
  Tanaka, Y., Sakamoto, A., Inoue, T., Yamada, T., Kikuchi, T., Kajimoto, T., Muraoka, O., Sato, A., Wataya, Y., Kim, H.-S, and Tanaka, R.
- Journal Title
  
  Tetrahedron
  
  Volume: 68 Pages: 3669-3677
- URL
  http://www.sciencedirect.com/science/article/pii/S0040402011019727
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22390024
[Journal Article] Andirolides H-P from the flower of andiroba (Carapa guianensis, Meliaceae).2012
- Author(s)
  Tanaka Y., Sakamoto A., Inoue T., Yamada T., Kikuchi T., Kajimoto T., Muraoka O., Sato A., Wataya Y., Kim H.-S., Tanaka R.
- Journal Title
  
  Tetrahedron
  
  Volume: 68 Pages: 3669-3677
- DOI
  10.1016/j.tet.2011.12.076
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22390024, KAKENHI-PROJECT-23659212
[Journal Article] Plasmodium falciparum endoplasmic reticulum-resident calcium binding protein is a possible target of synthetic antimalarial endoperoxides, N-89 and N-2512012
- Author(s)
  Morita M., Sanai H., Hiramoto A., Sato A., Hiraoka O., Sakura T., Kaneko O., Masuyama A., Nojima M., Wataya Y., Kim H.-S.
- Journal Title
  
  Journal of Proteome Research
  
  Volume: 11 Pages: 5704-5711
- DOI
  10.1021/pr3005315
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22390024, KAKENHI-PROJECT-23659212
[Journal Article] Plasmodium falciparumendoplasmic reticulum-resident calcium binding protein is a possible target of synthetic antimalarial endoperoxides, N-89 and N-251.2012
- Author(s)
  Morita, M., Sanai, H., Hiramoto, A., Sato, A., Hiraoka, O., Sakura, T., Kaneko, O., Masuyama, A., Nojima, M., Wataya, Y. and Kim, H.-S.
- Journal Title
  
  J Proteome Res.
  
  Volume: 11 Pages: 5704-5711
- URL
  http://pubs.acs.org/doi/pdf/10.1021/pr3005315
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22390024
[Journal Article] Plasmodium falciparumendoplasmic reticulum-resident calcium binding protein is a possible target of synthetic antimalarial endoperoxides, N-89 and N-2512012
- Author(s)
  Morita, M., Sanai, H., Hiramoto, A., Sato, A., Hiraoka, O., Sakura, T., Kaneko, O., Masuyama, A., Nojima, M., Wataya, Y. and Kim, H.-S.
- Journal Title
  
  J Proteome Res.
  
  Volume: 11 Pages: 5704-11
- URL
  http://pubs.acs.org/doi/pdf/10.1021/pr3005315
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23659212
[Journal Article] Schistosomicidal and antifecundity effects of oral treatment of synthetic endoperoxide N-89.2011
- Author(s)
  Taniguchi, T., Kumagai, T., Shimogawara, R., Ichinose, S., Hiramoto, A., Sato, A., Morita, M., Nojima, M., Kim, H.-S., Wataya, Y., Ohta, N.
- Journal Title
  
  arasitology International
  
  Volume: 60 Pages: 231-236
- URL
  http://www.sciencedirect.com/science/article/pii/S1383576911000225
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22390024
[Journal Article] Schistosomicidal and antifecundity effects of oral treatment of synthetic endoperoxide N-89.2011
- Author(s)
  Taniguchi T., Kumagai T., Shimogawara R., Ichinose S., Hiramoto A., Sato A., Morita M., Nojima M., Kim H.-S., Wataya Y., Ohta N.
- Journal Title
  
  Parasitology International
  
  Volume: 60 Pages: 231-236
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23659212
[Journal Article] Schistosomicidal and antifecundity effects of oral treatment of synthetic endoperoxide N-89.2011
- Author(s)
  Taniguchi T, Kumagai T, Shimogawara R, Ichinose S, Hiramoto A, Sato A, Morita M, Nojima M, Kim HS, Wataya Y, Ohta N.
- Journal Title
  
  Parasitol Int.
  
  Volume: (in press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22390024
[Journal Article] Antimalarial Activity of 6-(1,2,6,7-Tetraoxaspiro[7.11]nonadec-4-yl) hexan-1-ol (N-251) and Its Carboxylic Acid Derivatives2011
- Author(s)
  Sato A., Kawai S., Hiramoto A., Morita M., Tanigawa N., Nakase Y., Komichi Y., Matsumoto M., Hiraoka O., Hiramoto K., Tokuhara H., Masuyama A., Nojima M., Higaki K., Hayatsu H., Wataya Y., Kim H.-S.
- Journal Title
  
  Parasitology International
  
  Volume: 60 Pages: 488-492
- DOI
  10.1016/j.parint.2011.08.017
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22390024, KAKENHI-PROJECT-22590099
[Journal Article] Antimalarial Activity of Endoperoxide Compound 6-(1,2,6,7- Tetraoxaspiro[7.11] nonadec-4-yl)hexan-1-ol.2011
- Author(s)
  Sato A., Hiramoto A., Morita M., Matsumoto M., Komich Y., Nakase Y., Tanigawa N., Hiraoka O., Hiramoto K., Hayatsu H., Higaki K., Kawai S., Masuyama A., Nojima M., Wataya Y., Kim H.-S.
- Journal Title
  
  Parasitology International
  
  Volume: 60 Pages: 270-3
- URL
  http://dx.doi.org/10.1016/j.parint.2011.04.001
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23659212
[Journal Article] Antimalarial Activity of Endoperoxide Compound 6-(1,2,6,7-Tetraoxaspiro[7.11]nonadec-4-yl)hexan-1-ol.2011
- Author(s)
  Sato A., Hiramoto A., Morita M., Matsumoto M., Komichi Y., Nakase Y., Tanigawa N., Hiraoka O., Hiramoto K., Hayatsu H., Higaki K., Kawai S., Masuyama A., Nojima M., Wataya Y., Kim H.-S.
- Journal Title
  
  Parasitology International
  
  Volume: 60 Pages: 270-273
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23659212
[Journal Article] Antimalarial activity of 6-(1,2,6,7-tetraoxaspiro [7.11]nonadec-4-yl)hexan- 1-ol (N-251) and its carboxylic acid derivatives.2011
- Author(s)
  Sato A, Kawai S, Hiramoto A, Morita M, Tanigawa N, Nakase Y, Komichi Y, Matsumoto M, Hiraoka O, Hiramoto K, Tokuhara H, Masuyama A, Nojima M, Higaki K, Hayatsu H, Wataya Y, Kim HS.
- Journal Title
  
  Parasitol. Int.
  
  Volume: 60(4) Pages: 488-92
- URL
  http://www.sciencedirect.com/science/article/pii/S138357691100136X
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23659212
[Journal Article] Schistosomicidal and antifecundity effects of oral treatment of synthetic endo-peroxide N-892011
- Author(s)
  Taniguchi T., Kumagai T., Shimogawara R., Ichinose S., Hiramoto A., Sato A., Morita M., Nojima M., Kim H.-S., Wataya Y., Ohta N.
- Journal Title
  
  Parasitology International
  
  Volume: 60 Pages: 231-6
- URL
  http://dx.doi.org/10.1016/j.parint.2011.02.007
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23659212
[Journal Article] Antimalarial Activity of Endoperoxide Compound 6-(1,2,6,7- Tetraoxaspiro[7.11]nonadec-4-yl)hexan-1-ol.2011
- Author(s)
  Sato, A., Hiramoto, A., Morita, M., Matsumoto, M., Komich, Y., Nakase, Y., Tanigawa, N., Hiraoka, O., Hiramoto, K., Hayatsu, H., Higaki, K., Kawai, S., Masuyama, A., Nojima, M., Wataya,Y., Kim, H.-S.
- Journal Title
  
  Parasitol. Int.
  
  Volume: 60 Pages: 270-273
- URL
  http://www.sciencedirect.com/science/article/pii/S1383576911000444
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22390024
[Journal Article] Antimalarial activity of endoperoxide compound 6-(1,2,6,7-tetraoxaspiro [7.11]nonadec-4-yl)hexan-1-ol.2011
- Author(s)
  Sato, A., Hiramoto, A., Morita, M., Matsumoto M., Komichi Y., Nakase, Y., Tanigawa N., Hiraoka, O., Hiramoto, K., Hayatsu, H., Higaki, K., Kawai, A., Masuyama, A., Nojima, M., Wataya, Y., Kim, H.-S.
- Journal Title
  
  Parasitol Int.
  
  Volume: (in press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22390024
[Journal Article] tetraoxaspiro [7.11]nonadec-4-yl)hexan- 1-ol (N-251) and its carboxylic acid derivatives2011
- Author(s)
  Sato, A, Kawai, S., Hiramoto, A., Morita, M., Tanigawa, N., Nakase, Y., Komichi, Y., Matsumoto, M., Hiraoka, O., Hiramoto, K., Tokuhara, H., Masuyama, A., Nojima, M., Higaki, K., Hayatsu, H., Wataya,Y., Kim, H.-S.
- Journal Title
  
  Parasitol. Int
  
  Volume: 60 (4) Pages: 488-492
- URL
  http://www.sciencedirect.com/science/article/pii/S138357691100136X
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22390024
[Journal Article] Antimalarial Activity of Endoperoxide Compound 6-(1,2,6,7-Tetraoxaspiro[7.11]nonadec-4-yl)hexan-1-ol2011
- Author(s)
  Sato A., Hiramoto A., Morita M., Matsumoto M., Komichi Y., Nakase Y., Tanigawa N., Hiraoka O., Hiramoto K., Hayatsu H., Higaki K., Kawai S., Masuyama A., Nojima M., Wataya Y., Kim H.-S.
- Journal Title
  
  Parasitology International
  
  Volume: 60 Pages: 270-273
- DOI
  10.1016/j.parint.2011.04.001
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22390024, KAKENHI-PROJECT-22590099
[Journal Article] Schistosomicidal and antifecundity effects of oral treatment of synthetic endoperoxide N-892011
- Author(s)
  Taniguchi T, Kumagai T, Shimogawara R, Ichinose S, Hiramoto A, Sato A, Morita M, Nojima M, Kim HS, Wataya Y, Ohta N
- Journal Title
  
  Parasitol Int
  
  Volume: 60 Pages: 231-236
- DOI
  10.1016/j.parint.2011.02.007
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21406008, KAKENHI-PROJECT-22390024, KAKENHI-PROJECT-22790393
[Journal Article] Geranyl derivatices of isoquinoline alkaloids show increased biological activities.2010
- Author(s)
  Nishiyama, Y., Iwasa, K., Okada, S., Takeuchi, S., Moriyasu, M., Kamigauchi, M., Koyama, J., Takeuchi, A., Tokuda, H., Kim, H.-S., Wataya, Y., Takeda, K., Liu, Y., Wu, P., Bastow, K., Akiyama, T. and Lee, K
- Journal Title
  
  Heterocycles
  
  Volume: 81 Pages: 1193-1229
- URL
  http://www.heterocycles.jp/newlibrary/downloads/PDF/21203/81/5
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22390024
[Journal Article] Selective accumulation of rhodacyanine in plasmodial mitochondria is related to the growth inhibition of malaria parasites2010
- Author(s)
  Morisaki, D., Kim, H.-S., Inoue, H., Terauchi, H., Kuge, S., Naganuma, A., Wataya, Y., Tokuyama, H., Ihara, M. and Takasu, K
- Journal Title
  
  Chemical Science
  
  Volume: 1 Pages: 206-209
- URL
  http://pubs.rsc.org/en/content/articlepdf/2010/sc/c0sc00125b
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22390024
[Journal Article] Protein expression profiles of necrosis and apoptosis induced by 5-Fluoro-2´-deoxyuridine in mouse cancer cells.2010
- Author(s)
  Sato, A., Hiramoto, A., Wataya, Y. and Kim, H.-S.
- Journal Title
  
  Journal of Proteome Research
  
  Volume: 9 Pages: 1329-2338
- URL
  http://pubs.acs.org/doi/abs/10.1021/pr9010537
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22390024
[Journal Article] Toxoplasma gondii : A simple high throughput assay for drug screening in vitro2009
- Author(s)
  Jin C., Kaewintajuk K., Jiang J., Jeong W., Kamata M., Kim H.-S., Wataya Y. and Park H.
- Journal Title
  
  Exp. Parasitol. 121
  
  Pages: 132-136
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19041049
[Journal Article] 抗マラリア薬2008
- Author(s)
  綿矢有佑
- Journal Title
  
  ファルマシア 44
  
  Pages: 32-36
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19041049
[Journal Article] Detection of malaria parasites in mosquitoes from a malaria endemic area Chakaria, Bangladesh2008
- Author(s)
  Tangin A., komichi Y., Wagatsuma Y., Rashidul H., Wataya Y. and Kim H.-S.
- Journal Title
  
  Biol. Pharm. Bull. 31
  
  Pages: 703-708
- NAID
  110006680510
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19041049
[Journal Article] Antimalarial Effect of Bis-pyridinium Salts, N, N'-Hexamethylenebis(4-carbamoyl-1- alkvlpyridinium bromide).2006
- Author(s)
  Fujimoto, K., Morisaki, D., Yoshlda, M., Namba, T, Kim, T.-S., Wataya, Y., Kourai, H., Kakuta, H., Sasaki,K
- Journal Title
  
  Bioorg. Med. Chem. Lett. 16
  
  Pages: 2758-2760
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16390031
[Journal Article] Antimalarial Effect of Bis-pyridinium Salts, N,N'-Hexamethylenebis (4-carbamoy1-1- alkylpyridinium bromide).2006
- Author(s)
  Fujimoto, K., Morisaki, D., Yoshida, M., Namba, T., Kim, H.-S., Wataya, Y., Kourai, H., Kakuta, H., Sasaki, K.
- Journal Title
  
  Bioorg. Med. Chem. Lett. 16
  
  Pages: 2758-2760
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14021072
[Journal Article] Antimalarial Effect of Bis-pyridinium Salts, N, N'-Nexamethylenebis (4-carbamoyl-1-alkylpyridinium bromide).2006
- Author(s)
  Fujimoto, K., Morisaki, D., Yoshida, M., Namba, T., Kim, H.-S., Wataya, Y., Kourai, H., Kakuta, H., Sasaki, K.
- Journal Title
  
  Bioorg. Med. Chem. Lett. (In press)
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-14021072
[Journal Article] An apoptotic pathway of 3'-Ethynylcytidine(ECyd) involving the inhibition of RNA synthesis mediated by RNase L.2006
- Author(s)
  Naito T, Yokogawa T, Kim HS, Matsuda A, Sasaki T, Fukushima M, Kitade Y, Wataya Y
- Journal Title
  
  Nucleic Acids Symp Ser. 50
  
  Pages: 103-104
- Data Source
  KAKENHI-PROJECT-18659029
[Journal Article] Antimalarial Effect of Bis-pyridinium Salts, N, N'-Hexamethylenebis (4-carbamoyl-1-alkylpyridinium bromide).2006
- Author(s)
  Fujimoto, K., Morisaki, D., Yoshida, M., Namba, T., Kim, H.-S., Wataya, Y., Kourai, H., Kakuta, H., Sasaki, K.
- Journal Title
  
  Bioorg.Med.Chem.Lett., (In press)
- Data Source
  KAKENHI-PROJECT-14021072
[Journal Article] Antimalarial Effect of Bis-pyridinium Salts, N,N'-Hexamethylenebis (4-carbamoyl-1-alkylpyridinium bromide).2006
- Author(s)
  Fujimoto, K., Morisaki, D., Yoshida, M., Namba, T., Kim, H.-S., Wataya, Y., Kourai, H., Kakuta, H., Sasaki, K.
- Journal Title
  
  Bioorg.Med.Chem.Lett. 16
  
  Pages: 2758-2760
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16390031
[Journal Article] Antimalarial Effect of Bis-pyridinium Salts, N,N'-Hexamethylenebis(4-carbamoyl-1-alkylpyridinium bromide).2006
- Author(s)
  Fujimoto, K., Morisaki, D., Yoshida, M., Namba, T., Kim, H.-S., Wataya, Y, Kourai, H., Kakuta, H., Sasaki, K.
- Journal Title
  
  Bioorg.Med.Chem.Lett., (In press)
- Data Source
  KAKENHI-PROJECT-16390031
[Journal Article] Proteome and transcriptome analysis of 5-fluoro-2'-deoxyuridine-induced cell death mechanisms.2006
- Author(s)
  Sato A, Miyazaki E, SatakeA, Hiramoto A, Hiraoka O, Miyake T, Kim HS, Wataya Y
- Journal Title
  
  Nucleic Acids Symp Ser. 50
  
  Pages: 101-102
- Data Source
  KAKENHI-PROJECT-18659029
[Journal Article] Synthesis and evaluation of b-carbolinium cations as new antimalarial agents based on pi-delocalized lipophilic cation (DLC) hypothesis.2005
- Author(s)
  Takasu, K, Shimogama, T, Saiin, C, Kim, H.-S, Wataya, Y, Brun, R, Ihara, M.
- Journal Title
  
  Chem.Pharm.Bull., 53(6)
  
  Pages: 653-661
- Data Source
  KAKENHI-PROJECT-14021072
[Journal Article] Synthesis of novel siRNAs having thymidine dimers consisting of a carbamate or an urea linkage at their 3' overhang regions and their ability to suppress human RNase L protein expression.2005
- Author(s)
  Ueno, Y., Naito, T., Kawada, K., Shibata, A., Kim., H.-S., Wataya, Y., Kitade, Y.
- Journal Title
  
  Biol.Biophy.Res.Comm., 20,330(4)
  
  Pages: 1168-1175
- Data Source
  KAKENHI-PROJECT-16390031
[Journal Article] Inhibitory Mechanisms of 1-(3-C-ethynyl-b- D-ribo-pentofuranosyl)uracil (EUrd) on RNA Synthesis..2005
- Author(s)
  Yokogawa, T., Kanda, H., Takatori, S., Takenaka, K., Naito, T., Sasaki, T., Matsuda, A., Fukushima, M., Kim, H.-S., Wataya, Y.I
- Journal Title
  
  Nucleosides Nucleotides Nucleic Acids, 24(3)
  
  Pages: 227-232
- Data Source
  KAKENHI-PROJECT-16390031
[Journal Article] 1,2,4,5-Tetraoxan cycloalkanes : Synthesis and Antimalarial Activity.2005
- Author(s)
  Masuyama, A., Wu, J-M., Nojima, M., Kim, H.-S., Wataya, Y.
- Journal Title
  
  Mini-Reviews Med. chem. 5
  
  Pages: 1035-1043
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-14021072
[Journal Article] Synthesis of 5'-methylenearisteromycin and its 2-fluoro congener with potent antimalarial activity due to the parasite S-adenosyl homocysteine hydrolase Inhibition.2005
- Author(s)
  Takagi, T., Sukeda, M., Kim, H.-S., Wataya, Y., Kitade, Y., Matsuda, A., Shuto, S.
- Journal Title
  
  Org.Biomol.Chem. 3
  
  Pages: 1245-1251
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16390031
[Journal Article] Sequence analysis of the 5'-flanking regions of human dihydropyrimidine dehydrogenase gene : Identification of a new polymorphism related with effects of 5-fluorouracil.2005
- Author(s)
  Hasegawa, T., Kim, H-S., Fukushima, M.,, Wataya, Y.
- Journal Title
  
  Nucleosides Nucleotides Nucleic Acids, 24(4)
  
  Pages: 233-242
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16390031
[Journal Article] Inhibitory Mechanisms of 1-(3-C-ethynyl-b-D-ribo-pentofuranosyl) uracil ( EUrd ) on RNA Synthesis.2005
- Author(s)
  Yokogawa, T., Kanda, H., Takatori, S., Takenaka, K., Naito, T., Sasaki, T., Matsuda, A., Fukushima, M., Kim, H-S., Wataya,Y.
- Journal Title
  
  Nucleosides Nucleotides Nucleic Acids, 24(3)
  
  Pages: 227-232
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16390031
[Journal Article] Synthesis of 5'-methylenearisteromycin and its 2-fluoro congener with potent antimalarial activity due to the parasite S-adenosyl homocysteine hydrolase Inhibition.2005
- Author(s)
  Takagi, T., Sukeda, M., Kim.H.-S., Wataya, Y., Kitada, Y., Matsuda, A., Shuto, S.
- Journal Title
  
  Org.Bjomol. Chem., 3
  
  Pages: 1245-1251
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16390031
[Journal Article] Sequence analysis of the 5'flanking regions of human dihydropyrimidine dehydrogenase gene : Identification of a new polymorphism related with effects of 5-fluorouracil.2005
- Author(s)
  Hasegawa, T., Kim, H.-S., Fukushima, M., Wataya, Y.
- Journal Title
  
  Nucleosides Nucleotides Nucleic Acids 24.4
  
  Pages: 233-242
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-14021072
[Journal Article] Co-catalyzed autoxidation of alkene in the presence of silane. The effect of the structure of silanes on the efficiency of the reaction and on the product distribution.2005
- Author(s)
  Wu, J.-M., Kunikawa, S., Tokuyasu, T., Masuyama, A., Nojima, M., Kim, H.-S., Wataya, Y.
- Journal Title
  
  Tetrahedron 61
  
  Pages: 9961-9968
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16390031
[Journal Article] Inhibitory Mechanisms of 1-(3-C-ethynyl-b- D-ribo-pentofuranosyl)uracil (EUrd) on RNA Synthesis..2005
- Author(s)
  Yokogawa, T., Kanda, H., Takatori, S., Takenaka, K., Naito, T., Sasaki, T., Matsuda, A., Fukushima, M., Kim, H.-S., Wataya, Y.I
- Journal Title
  
  Nucleosides Nucleotides Nucleic Acids, 24(3)
  
  Pages: 227-232
- Data Source
  KAKENHI-PROJECT-14021072
[Journal Article] Synthesis and biological activity of fatty acid conjugate of quinine.2005
- Author(s)
  Kumura, N., Izumi, M.Nakajima, S., Shimizu, S., Kim, H.-S., Wataya, Y., Baba, N.
- Journal Title
  
  Biosci.Biotech.Biochem. 69(11)
  
  Pages: 2250-2253
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16390031
[Journal Article] Synthesis and in vitro antimalarial activity of some simple peroxyplakoric acid analogues.2005
- Author(s)
  Liu, H., Jin, H., Zhang, Q., Wu, Y., Kim, H.-S., Wataya, Y.
- Journal Title
  
  Chinese J.Chem. 23
  
  Pages: 1469-1473
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16390031
[Journal Article] Synthesis of novel siRNAs having thymidine dimers consisting of a carbamate or an urea linkage at their 3' overhang regions and their ability to suppress human RNase L protein expression.2005
- Author(s)
  Ueno, Y., Naito, T., Kawada, K., Shibata, A., Kim, H.-S., Wataya, Y, Kitade, Y.
- Journal Title
  
  Biol.Biophy.Res.Comm., 20,330(4)
  
  Pages: 1168-1175
- Data Source
  KAKENHI-PROJECT-14021072
[Journal Article] Synthesis and biological activity of fatty acid conjugate of quinine.2005
- Author(s)
  Kumura, N., Izumi, M., Nakajima, S., Shimizu, S., Kim, H.-S., Wataya, Y., Baba, N.
- Journal Title
  
  Biosci.Biotech.Biochem., 69(11)
  
  Pages: 2250-2253
- Data Source
  KAKENHI-PROJECT-14021072
[Journal Article] Synthesis and evaluation of □-carbolinium cations as new antimalarial agents based on pi-delocalized lipophilic cation (DLC) hypothesis.2005
- Author(s)
  Takasu, K, Shimogama, T, Saiin, C, Kim, H.-S, Wataya, Y, Brun, R, Ihara, M.
- Journal Title
  
  Chem. Pharm. Bull. 53.6
  
  Pages: 653-661
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-14021072
[Journal Article] Synthesis of 5'-methylenearisteromycin and its 2-fluoro congener with potent antimalarial activity due to the parasite S-adenosyl homocysteine hydrolase Inhibition.2005
- Author(s)
  Takagi, T., Sukeda, M., Kim, H.-S., Wataya, Y, Kitade, Y., Matsuda, A., Shuto.S.
- Journal Title
  
  Org. Biomol. Chem. 3
  
  Pages: 1245-1251
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-14021072
[Journal Article] Synthesis and evaluation of □-carbolinium cations as new antimalarial agents based on pi-delocalized lipophilic cation (DLC) hypothesis.2005
- Author(s)
  Takasu, K, Shimogama, T, Saiin, C, Kim, H.-S, Wataya, Y, Brun, R, Ihara, M.
- Journal Title
  
  Chem. Pharm. Bull. 53 (6)
  
  Pages: 653-61
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14021072
[Journal Article] Sequence analysis of the 5'-flanking regions of human dihydropyrimidine dehydrogenase gene : Identification of a new polymorphism related with effects of 5-fluorouracil.2005
- Author(s)
  Hasegawa, T., Kim, H.-S., Fukushima, M., Wataya, T.
- Journal Title
  
  Nucleosides Nucleotides Nucleic Acids 24(4)
  
  Pages: 233-242
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16390031
[Journal Article] Synthesis of 5'-methylenearisteromycin and its 2-fluoro congener with potent antimalarial activity due to the parasite S-adenosyl homocysteine hydrolase Inhibition.2005
- Author(s)
  Takagi, T., Sukeda, M., Kim, H.-S., Wataya, Y., Kitade, Y., Matsuda, A., Shuto.S.
- Journal Title
  
  Org. Biomol. Chem. 3
  
  Pages: 1245-1251
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14021072
[Journal Article] Co-catalyzed autoxidation of alkene in the presence of silane. The effect of the structure of silanes on the efficiency of the reaction and on the product distribution.2005
- Author(s)
  Wu, J.-M., Kunikawa, S., Tokuyasu, T., Masuyama, A., Nojima, M., Kim, H.-S., Wataya, Y.
- Journal Title
  
  Tetrahedron 61
  
  Pages: 9961-9968
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-14021072
[Journal Article] Synthesis and biological activity of fatty acid conjugate of quinine.2005
- Author(s)
  Kumura, N., Izumi, M., Nakajima, S., Shimizu, S., Kim, H.-S., Wataya, Y., Baba, N.
- Journal Title
  
  Biosci. Biotech. Biochem. 69(11)
  
  Pages: 2250-2253
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14021072
[Journal Article] 1,2,4,5-Tetraoxan cycloalkanes : Synthesis and Antimalarial Activity.2005
- Author(s)
  Masuyama, A., Wu, J-M., Nojima, M., Kim, H.-S., Wataya, Y.
- Journal Title
  
  Mini-Reviews Med. Chem. 5
  
  Pages: 1035-1043
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14021072
[Journal Article] 1,2,4,5-Tetraoxan cycloalkanes : Synthesis and Antimalarial Activity.2005
- Author(s)
  Masuyama, A., Wu, J-M., Nojima, M., Kim, H.-S., Wataya, Y.
- Journal Title
  
  Mini-Reviews Med.Chem. 5
  
  Pages: 1035-1043
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16390031
[Journal Article] Synthesis of 5'-methylenearisteromycin and its 2-fluoro congener with potent antimalarial activity due to the parasite S-adenosyl homocysteine hydrolase Inhibition2005
- Author(s)
  Takagi, T., Sukeda, M., Kim, H.-S., Wataya, Y., Kitade, Y, Matsuda, A., Shuto.S.
- Journal Title
  
  Org.Biomol.Chem., 3
  
  Pages: 1245-1251
- Data Source
  KAKENHI-PROJECT-16390031
[Journal Article] Synthesis and biological activity of fatty acid conjugate of quinine.2005
- Author(s)
  Fumura, N., lzumi, M., Nakajima, S., Shimizu, S., Kim, H, -S., Wataya, Y., Baba,N.
- Journal Title
  
  Biosci. Biotech. Biochem. 69(11)
  
  Pages: 2250-2253
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16390031
[Journal Article] Synthesis and evaluation of b-carbolinium cations as new antimalarial agents based on pi-delocalized lipophilic cation (DLC) hypothesis.2005
- Author(s)
  Takasu, K, Shimogama, T, Saiin, C, Kim.H.-S., Wataya, Y., Brun, R, Ihara,M
- Journal Title
  
  Chem. Pharm. Bull., 53(6)
  
  Pages: 653-661
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16390031
[Journal Article] Sequence analysis of the 5--flanking regions of human dihydropyrimidine dehydrogenase gene : Identification of a new polymorphism related with effects of 5-fluorouracil.2005
- Author(s)
  Hasegawa, T., Kim, H.-S., Fukushima, M., Wataya,Y.
- Journal Title
  
  Nucleosides Nucleotides Nucleic Acids 24 (4)
  
  Pages: 233-242
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14021072
[Journal Article] Synthesis and biological activity of fatty acid conjugate of quinine.2005
- Author(s)
  Kumura, N., Izumi, M., Nakajima, S., Shimizu, S., Kim, H.-S., Wataya, Y., Baba, N.
- Journal Title
  
  Biosci.Biotech.Biochem., 69(11)
  
  Pages: 2250-2253
- Data Source
  KAKENHI-PROJECT-16390031
[Journal Article] Synthesis of novel siRNAs having thymidine dimers consisting of a carbamate or an urea linkage at their 3' overhang regions and their ability to suppress human RNase L protein expression.2005
- Author(s)
  Ueno, Y., Naito, T., Kawada, K., Shibata, A., Kim, H.-S., Wataya, Y., Kitade, Y.
- Journal Title
  
  Biol. Biophy. Res. Comm. 20, 330(4)
  
  Pages: 1168-1175
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14021072
[Journal Article] Synthesis of novel siRNAs having thymidine dimers consisting of a carbamate or an urea linkage at their 3' overhang regions and their ability to suppress human RNase L protein expression.2005
- Author(s)
  Ueno, Y., Naito, T., Kawada, K., Shibata, A., Kim, H.-S., Wataya, Y, Kitade, Y.
- Journal Title
  
  Biol. Biophy. Res. Comm. 20, 330.4
  
  Pages: 1168-1175
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-14021072
[Journal Article] Inhibitory Mechanisms of 1-(3-C-ethynyl-^-D-ribo-pentofuranosyl)uracil (EUrd) on RNA Synthesis.2005
- Author(s)
  Yokogawa, T., Kanda, H., Takatori, S., Takenaka, K., Naito, T., Sasaki, T., Matsuda, A., Fukushima, M., Kim, H.-S., Wataya, Y.
- Journal Title
  
  Nucleosides Nucleotides Nucleic Acids 24 (3)
  
  Pages: 227-232
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14021072
[Journal Article] Synthesis of 5'-methylenearisteromycin and its 2-fluoro congener with potent antimalarial activity due to the parasite S-adenosyl homocysteine hydrolase Inhibition.2005
- Author(s)
  Takagi, T., Sukeda, M., Kim, H.-S., Wataya, Y., Kitade, Y., Matsuda, A., Shuto, S.
- Journal Title
  
  Org.Biomol.Chem., 3
  
  Pages: 1245-1251
- Data Source
  KAKENHI-PROJECT-14021072
[Journal Article] Inhibitory Mechanisms of 1-(3-Cethynyl-□-D-ribo-pentofuranosyl)uracil(EUrd)on RNAsynthesis.2005
- Author(s)
  Yokogawa, T, Kanda, H., Takatori, S, Takenaka, K, Naito, T., Sasaki, T, Matsuda, A., Fukushima, M., Kim, H.-S, Wataya, Y.I
- Journal Title
  
  Nucleosides Nucleotides Nucleic Acids 24.3
  
  Pages: 227-232
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-14021072
[Journal Article] Sequence analysis of the 5'-flanking regions of human dihydropyrimidine dehydrogenase gene : Identification of a new polymorphism related with effects of 5-fluorouracil.2005
- Author(s)
  Hasegawa, T., Kim, H.-S., Fukushima, M., Wataya, Y.
- Journal Title
  
  Nucleosides Nucleotides Nucleic Acids, 24(4)
  
  Pages: 233-242
- Data Source
  KAKENHI-PROJECT-16390031
[Journal Article] Synthesis and evaluation of b-carbolinium cations as new antimalarial agents based on pi-delocalized lipophilic cation (DLC) hypothesis.2005
- Author(s)
  Takasu, K, Shimogama, T, Saiin, C, Kim, H.-S, Wataya, Y, Brun, R, Ihara, M.
- Journal Title
  
  Chem.Pharm.Bull., 53(6)
  
  Pages: 653-661
- Data Source
  KAKENHI-PROJECT-16390031
[Journal Article] 1, 2, 4, 5 - Tetraoxan cycloalkanes : Synthesis and Antimalarial Activity.2005
- Author(s)
  Masuyama, A., Wu, J-M., Nojima, M., Kim, H-S., Wataya,Y.
- Journal Title
  
  Mlnl-Reviews Med. chem. 5
  
  Pages: 1035-1043
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16390031
[Journal Article] Inhibitory Mechanisms of 1-(3-C-ethynyl-b-D-ribo-pentofuranosyl)uracil (EUrd) on RNA Synthesis.2005
- Author(s)
  Yokogawa, T., Kanda, H., Takatori, S., Takenaka, K., Naito, T., Sasaki, T., Matsuda, A., Fukushima, M., Kim, H.-S., Wataya, Y.
- Journal Title
  
  Nucleosides Nucleotides Nucleic Acids 24(3)
  
  Pages: 227-232
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16390031
[Journal Article] Sequence analysis of the 5'-flanking regions of human dihydropyrimidine dehydrogenase gene : Identification of a new polymorphism related with effects of 5-fluorouracil.2005
- Author(s)
  Hasegawa, T., Kim, H.-S., Fukushima, M., Wataya, Y.
- Journal Title
  
  Nucleosides Nucleotides Nucleic Acids, 24(4)
  
  Pages: 233-242
- Data Source
  KAKENHI-PROJECT-14021072
[Journal Article] Synthesis of novel siRNAs having thymidine dimers consisting of a carbamate or an urea linkage at their 3 ' overhang regions and their ability to suppress human RNase L protein expression.2005
- Author(s)
  Ueno, Y., Naito, T., Kawada, K., Shibata, A., Kim.H.-S., Wataya, Y., Kitada,Y.
- Journal Title
  
  Biol.Biophy.Res.Comm. 20,330(4)
  
  Pages: 1168-1175
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16390031
[Journal Article] Synthesis of novel siRNAs having thymidine dimers consisting of a carbamate or an urea linkage at their 3' overhang regions and their ability to suppress human RNase L protein expression.2005
- Author(s)
  Ueno, Y., Naito, T., Kawada, K., Sibata, A., Kim, H.-S., Wataya, Y., Kitabe, Y.
- Journal Title
  
  Biol.Biophy.Res.Comm. 20,330(4)
  
  Pages: 1168-1175
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16390031
[Journal Article] 1,2,4,5-Tetraoxan cycloalkanes : Synthesis and Antimalarial Activity.2005
- Author(s)
  Masuyama, A., Wu, J-M., Nojima, M., Kim, H.-S., Wataya, Y.
- Journal Title
  
  Mini-Reviews Med.chem. 5
  
  Pages: 1035-1043
- Data Source
  KAKENHI-PROJECT-14021072
[Journal Article] 1,2,4,5-Tetraoxan cycloalkanes : Synthesis and Antimalarial Activity.2005
- Author(s)
  Masuyama, A., Wu, J-M., Nojima, M., Kim, H.-S., Wataya, Y.
- Journal Title
  
  Mini-Reviews Med.chem. 5
  
  Pages: 1035-1043
- Data Source
  KAKENHI-PROJECT-16390031
[Journal Article] Synthesis and in vitro antimalarial activity of some simple peroxyplakoric acid analogues.2005
- Author(s)
  Liu, H., Jin, H.Zhang, Q., Wu, Y., Kim, H, -S, Wataya,Y.
- Journal Title
  
  Chinese J.Chem. 23
  
  Pages: 1469-1473
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16390031
[Journal Article] Co-catalyzed autoxidation of alkene in the presence of silane. The effect of the structure of silanes on the efficiency of the reaction and on the product distribution.2005
- Author(s)
  Wu, J.-M., Kunikawa, S., Tokuyasu, T., Masuyama, A., Nojima, M., Kim, H.-S., Wataya, Y.
- Journal Title
  
  Tetrahedron, 61
  
  Pages: 9961-9968
- Data Source
  KAKENHI-PROJECT-14021072
[Journal Article] Co-catalyzed autoxidation of alkene in the presence of silane. The effect of the structure of silanes on the efficiency of the reaction and on the product distribution.2005
- Author(s)
  Wu, J.-M., Kunikawa, S., Tokuyasu, T., Masuyama, A., Nojima, M., Kim, H.-S., Wataya, Y
- Journal Title
  
  Tetrahedron, 61
  
  Pages: 9961-9968
- Data Source
  KAKENHI-PROJECT-16390031
[Journal Article] Synthesis and biological activity of fatty acid conjugate of quinine.2005
- Author(s)
  Kumura, N., Izumi, M., Nakajima, S., Shimizu, S., Kim, H.-S., Wataya, Y, Baba, N.
- Journal Title
  
  Biosci. Biotech. Biochem. 69.11
  
  Pages: 2250-2253
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-14021072
[Journal Article] Synthesis and evaluation of b-carbolinium cations as new antimalarial agents based on pi-delocalized lipophilic cation (DLC) hypothesis.2005
- Author(s)
  Takasu, K, Shimogama, T, Saiin, C, Kim, H.-S, Wataya, Y, Brun, R, Ihara, M.
- Journal Title
  
  Chem.Pharm.Bull. 53(6)
  
  Pages: 653-661
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16390031
[Journal Article] Duffy antigen is important for lethality of the lethal strain P.yoelii 17XL,2004
- Author(s)
  Akimitsu, N., Kim, H.-S., Ono, K., Wataya, Y., Torii, M., Sekimizu, K.
- Journal Title
  
  Parasitolgy Res. 93
  
  Pages: 499-530
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16390031
[Journal Article] p Delocalized b-carbolinium cations as potential antiamlarials.2004
- Author(s)
  Takasu, K., Shimogama, T., Saiin, C., Kim, H.-S., Wataya, Y., Ihara, M.
- Journal Title
  
  Bioorg.Med.Chem.Lett. 14
  
  Pages: 1689-1692
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16390031
[Journal Article] Antimalarial Activity of Lavandulyl Flavanones Isolated from the Roots of Sophora flavescens.2004
- Author(s)
  Kim, Y.-C, Kim, H.-S., Wataya, Y., Sohn, D.-H., Kang, T, -H., Kim, M.-S., Kim, Y.-M., Lee, K.-M., Chang, J.-D., Park,H.
- Journal Title
  
  Biol.Pharm.Bull. 25
  
  Pages: 748-750
- NAID
  110003608846
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16390031
[Journal Article] Duffy antigen is important for lethality of the lethal strain P. yoelii 17XL2004
- Author(s)
  Akimitsu, N., Kim, H-S., Ono, K., Wataya, Y., Torii, M.Sekimizu,K.
- Journal Title
  
  Parasltolgy Res. 93
  
  Pages: 499-503
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16390031
[Journal Article] 抗原虫薬2004
- Author(s)
  金惠淑, 綿矢有佑, 木村幹男, 益山新樹, 野島正朋
- Journal Title
  
  臨床と微生物
  
  Pages: 5-5
- NAID
  10015599985
- Data Source
  KAKENHI-PROJECT-14021072
[Journal Article] Duffy antigen is important for lethality of the lethal strain P.yoelii 17XL2004
- Author(s)
  Akimitsu, N., Kim, H.-S., Ono, K., Wataya, Y., Torii, M., Sekimizu, K.
- Journal Title
  
  Parasitolgy Res. 93
  
  Pages: 499-530
- Data Source
  KAKENHI-PROJECT-16390031
[Journal Article] Antimalarial Activity of Lavandulyl Flavanones Isolated from the Roots of Sophora flavescens.2004
- Author(s)
  Kim, Y.-C., Kim, H.-S., Wataya, Y., Sohn, D.-H., Kang, T.-H., Kim, M.-S., Kim, Y.-M., Lee, K.-M., Chang, J.-D., Park, H.
- Journal Title
  
  Biol.Pharm.Bull. 25
  
  Pages: 748-750
- NAID
  110003608846
- Data Source
  KAKENHI-PROJECT-16390031
[Journal Article] Duffy antigen is important for lethality of the lethal strain P.yoelii 17XL2004
- Author(s)
  Akimitsu, N., Kim, H.-S., Ono, K., Wataya, Y., Torii, M., Sekimizu, K.
- Journal Title
  
  Parasitolgy Res. 93
  
  Pages: 499-530
- Data Source
  KAKENHI-PROJECT-14021072
[Journal Article] Antimalarial Activity of Lavandulyl Flavanones Isolated from the Roots of Sophora flavescens.2004
- Author(s)
  Kim, Y.-C., Kim, H.-S., Wataya, Y., Sohn, D.-H., Kang, T.-H., Kim, M.-S., Kim, Y.-M., Lee, K.-M., Chang, J.-D., Rark, H.
- Journal Title
  
  Biol.Pharm.Bull. 27(5)
  
  Pages: 748-750
- NAID
  110003608846
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16390031
[Journal Article] Antimalarial Activity of Lavandulyl Flavanones Isolated from the Roots of Sophora flavescens.2004
- Author(s)
  Kim, Y.-C., Kim, H.-S., Wataya, Y., Sohn, D.-H., Kang, T.-H., Kim, M.-S., Kim, Y.-M., Lee, K.-M., Chang, J.-D., Park, H.
- Journal Title
  
  Biol.Pharm.Bull. 25
  
  Pages: 748-750
- NAID
  110003608846
- Data Source
  KAKENHI-PROJECT-14021072
[Journal Article] Synthesis of 5'-methylenearisteromycin and its 2-fluoro congener with potent antimalarial activity due to the parasite S-adenosyl homocysteine hydrolase Inhibition.
- Author(s)
  Takagi, T., Sukeda, M., Kim, H.-S., Wataya, Y., Kitade, Y., Matsuda, A., Shuto, S.
- Journal Title
  
  SBO (In press)
- Data Source
  KAKENHI-PROJECT-14021072
[Journal Article] Synthesis of 5'-methylenearisteromycin and its 2-fluoro congener with potent antimalarial activity due to the parasite S-adenosyl homocysteine hydrolase Inhibition.
- Author(s)
  Takagi, T., Sukeda, M., Kim, H.-S., Wataya, Y., Kitade, Y., Matsuda, A., Shuto, S.
- Journal Title
  
  SBO (In press)
- Data Source
  KAKENHI-PROJECT-16390031
[Journal Article] 1,2,4,5-Tetraoxan cycloalkanes : Synthesis and Antimalarial Activity.
- Author(s)
  Masuyama, A., Wu, J-M., Nojima, M., Kim, H.-S., Wataya, Y.
- Journal Title
  
  MRMC (In press)
- Data Source
  KAKENHI-PROJECT-14021072
[Journal Article] Sequence analysis of the 5'-flanking regions of human dihydropyrimidine dehydrogenase gene : Identification of a new polymorphism related with effects of 5-fluorouracil.
- Author(s)
  Hasegawa, T., Kim, H.-S., Fukushima, M., Wataya, Y.
- Journal Title
  
  Nucleosides Nucleotides Nucleic Acids (In press)
- Data Source
  KAKENHI-PROJECT-14021072
[Journal Article] Sequence analysis of the 5'-flanking regions of human dihydropyrimidine dehydrogenase gene : Identification of a new polymorphism related with effects of 5-fluorouracil.
- Author(s)
  Hasegawa, T., Kim, H.-S., Fukushima, M., Wataya, Y.
- Journal Title
  
  Nucleosides Nucleotides Nucleic Acids (In press)
- Data Source
  KAKENHI-PROJECT-16390031
[Journal Article] 1,2,4,5-Tetraoxan cycloalkanes : Synthesis and Antimalarial Activity.
- Author(s)
  Masuyama, A., Wu, J-M., Nojima, M., Kim, H.-S., Wataya, Y.
- Journal Title
  
  MRMC (In press)
- Data Source
  KAKENHI-PROJECT-16390031
[Patent] 特許新規抗住血吸虫剤2008
- Inventor(s)
  綿矢有佑, 金恵淑, 平本晃子, 佐藤聡, 太田伸生, 熊谷貴, 下河原理江子, 谷口斎恵
- Industrial Property Rights Holder
  岡山大学
- Filing Date
  2008-07-01
- Data Source
  KAKENHI-PROJECT-19041049
[Patent] ヘムへの配位能を有する抗マラリア活性化合物2006
- Inventor(s)
  樋口恒彦, 大宮弘久, 梅澤直樹, 金惠淑, 綿矢有佑
- Industrial Property Rights Holder
  樋口恒彦
- Industrial Property Number
  2006-049678
- Filing Date
  2006-02-28
- Data Source
  KAKENHI-PROJECT-14021072
[Patent] ヘムへの配置能を有する抗マラリア活性化合物2006
- Inventor(s)
  樋口恒彦, 大宮弘久, 梅澤直樹, 金惠子淑, 綿矢有佑
- Industrial Property Rights Holder
  樋口恒彦
- Industrial Property Number
  2006-049678
- Filing Date
  2006-02-28
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16390031
[Patent] ヘムへの配位能を有する抗マラリア活性化合物2006
- Inventor(s)
  樋口恒彦, 大宮弘久, 梅澤直樹, 金恵淑, 綿矢有佑
- Industrial Property Rights Holder
  樋口恒彦
- Industrial Property Number
  2006-049678
- Filing Date
  2006-02-28
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-14021072
[Patent] ヘムへの配位能を有する抗マラリア活性化合物2006
- Inventor(s)
  樋口恒彦, 大宮弘久, 梅澤直樹, 金惠淑, 綿矢有佑
- Industrial Property Rights Holder
  樋口恒彦
- Industrial Property Number
  2006-049678
- Filing Date
  2006-02-28
- Data Source
  KAKENHI-PROJECT-16390031
[Presentation] 経皮吸収型抗マラリア薬の開発研究2013
- Author(s)
  中村由香、片本茜、佐藤聡、檜垣和孝、綿矢有佑、金惠淑
- Organizer
  日本薬学会第133年会
- Place of Presentation
  横浜、神奈川
- Data Source
  KAKENHI-PROJECT-22390024
[Presentation] 経皮吸収型抗マラリア薬の開発研究2013
- Author(s)
  中村由香、片本茜、佐藤聡、檜垣和孝、綿矢有佑、金惠淑
- Organizer
  日本薬学会第133年会
- Place of Presentation
  横浜、神奈川
- Data Source
  KAKENHI-PROJECT-23659212
[Presentation] 難治性感染症治療薬の開発研究2013
- Author(s)
  金惠淑、佐藤聡、森田将之、綿矢有佑、熊谷貴、下河原理江子、太田伸生
- Organizer
  日本薬学会第133年会
- Place of Presentation
  横浜、神奈川
- Data Source
  KAKENHI-PROJECT-23659212
[Presentation] 難治性感染症治療薬の開発研究2013
- Author(s)
  金惠淑、佐藤聡、森田将之、綿矢有佑、熊谷貴、下河原理江子、太田伸生
- Organizer
  日本薬学会第133年会
- Place of Presentation
  横浜、神奈川
- Data Source
  KAKENHI-PROJECT-22390024
[Presentation] Drug development research for antimalarial endoperoxide N-2512012
- Author(s)
  Masayuki Morita, Akiko Hiramoto, Kazuaki Okada, Tatsuya Wakimoto, Akane Katamoto, Hiroki Watanabe, Takuma Takahashi, Chikako Imada, Akira Sato, Kazutaka Higaki, Yusuke Wataya, Hye-Sook Kim
- Organizer
  Forum Cheju 15; The 15th Japan-Korea Parasitologists’ Seminar
- Place of Presentation
  Miyazaki, Japan
- Data Source
  KAKENHI-PROJECT-22390024
[Presentation] 新規抗マラリア薬・環状過酸化化合物の開発研究2012
- Author(s)
  森田将之、平本晃子、佐藤聡、岡田和朗、鎌井一気、脇本達也、林孝輔、片本茜、渡部裕紀、高橋拓真、今田智加子、平岡修、野島正朋、檜垣和孝、綿矢有佑,金惠淑
- Organizer
  日本薬学会第132 年会
- Place of Presentation
  札幌
- Data Source
  KAKENHI-PROJECT-23659212
[Presentation] 新規抗マラリア薬・環状過酸化化合物の開発研究2012
- Author(s)
  森田将之、平本晃子、佐藤聡、岡田和朗、鎌井一気、脇本達也、林孝輔、片本茜、渡部裕紀、高橋拓真、今田智加子、平岡修、野島正朋、檜垣和孝、綿矢有佑,金惠淑
- Organizer
  日本薬学会第132 年会
- Place of Presentation
  札幌
- Data Source
  KAKENHI-PROJECT-22390024
[Presentation] 環状過酸化化合物N-251の生物学的利用能向上を目的とする開発研究2012
- Author(s)
  片本茜、脇本達也、渡部裕紀、森田将之、林孝輔、佐藤聡、綿矢有佑、高橋拓真、今田智加子、檜垣和孝、金惠淑
- Organizer
  第72回日本寄生虫学会東日本支部会, 第10回分子寄生虫・マラリアフォーラム
- Place of Presentation
  前橋、群馬
- Data Source
  KAKENHI-PROJECT-23659212
[Presentation] Drug development research for antimalarial endoperoxide N-2512012
- Author(s)
  Masayuki Morita, Akiko Hiramoto, Kazuaki Okada, Tatsuya Wakimoto, Akane Katamoto, Hiroki Watanabe, Takuma Takahashi, Chikako Imada, Akira Sato, Kazutaka Higaki, Yusuke Wataya, Hye-Sook Kim
- Organizer
  Forum Cheju 15; The 15th Japan-Korea Parasitologists’ Seminar
- Place of Presentation
  Miyazaki, Japan
- Data Source
  KAKENHI-PROJECT-23659212
[Presentation] 環状過酸化化合物N-251 の生物学的利用能向上を目的とする開発研究2012
- Author(s)
  片本茜、脇本達也、渡部裕紀、森田将之、林孝輔、佐藤聡、綿矢有佑、高橋拓真、今田智加子、檜垣和孝、金惠淑
- Organizer
  第72回日本寄生虫学会東日本支部会, 第10回分子寄生虫・マラリアフォーラム
- Place of Presentation
  前橋、群馬
- Data Source
  KAKENHI-PROJECT-22390024
[Presentation] 環状過酸化化合物N-251の生物学的利用能向上を目的とする開発研究2012
- Author(s)
  片本茜、脇本達也、渡部裕紀、森田将之、林孝輔、佐藤聡、綿矢有佑、高橋拓真、今田智加子、檜垣和孝、金惠淑
- Organizer
  第72回日本寄生虫学会東日本支部会, 第10回分子寄生虫・マラリアフォーラム
- Place of Presentation
  前橋、群馬
- Data Source
  KAKENHI-PROJECT-22390024
[Presentation] 合成環状過酸化化合物N-89投与によるマンソン住血吸虫体内のヘモゾイン蓄積量に与える影響2011
- Author(s)
  谷口斎恵、熊谷貴、下河原理江子、平本晃子、佐藤聡、金惠淑、綿矢有佑、太田伸生
- Organizer
  第80回日本寄生虫学会大会
- Place of Presentation
  東京
- Year and Date
  2011-07-18
- Data Source
  KAKENHI-PROJECT-23659212
[Presentation] 合成環状過酸化化合物N-89投与によるマンソン住血吸虫体内のヘモゾイン蓄積量に与える影響2011
- Author(s)
  谷口斎恵、熊谷貴、下河原理江子、平本晃子、佐藤聡、金惠淑、綿矢有佑、太田伸生
- Organizer
  第80回日本寄生虫学会大会
- Place of Presentation
  東京
- Year and Date
  2011-07-18
- Data Source
  KAKENHI-PROJECT-22390024
[Presentation] 新規抗住血吸虫薬の開発研究2010
- Author(s)
  金惠淑、平本晃子、佐藤聡、森田将之、熊谷貴、下河原理江子、谷口斎恵、奈良武司、太田伸生、綿矢有佑
- Organizer
  第33回日本分子生物学会年会第83回日本生化学会大会合同大会
- Place of Presentation
  神戸
- Year and Date
  2010-12-08
- Data Source
  KAKENHI-PROJECT-22390024
[Presentation] 合成環状過酸化化合物N-89投与によるマンソン住血吸虫のヘモグロビン代謝への影響2010
- Author(s)
  谷口斎恵、熊谷貴、下河原理江子、平本晃子、佐藤聡、金惠淑、綿矢有佑、太田伸生
- Organizer
  第79回日本寄生虫学会大会
- Place of Presentation
  旭川
- Year and Date
  2010-05-21
- Data Source
  KAKENHI-PROJECT-22390024
[Presentation] 新規抗住血吸虫薬の開発研究2010
- Author(s)
  金惠淑、平本晃子、佐藤聡、森田将之、熊谷貴、下河原理江子、谷口斎恵、奈良武司、太田伸生、綿矢有佑
- Organizer
  第33回日本分子生物学会年会、第83回日本生化学会大会合同大会
- Place of Presentation
  神戸
- Year and Date
  2010-12-08
- Data Source
  KAKENHI-PROJECT-22390024
[Presentation] 環状過酸化化合物N-89投与時のマンソン住血吸虫プロテオーム解析2010
- Author(s)
  平本晃子、佐藤聡、森田将之、綿矢有佑、熊谷貴、下河原理江子、谷口斎恵、太田伸生、金惠淑
- Organizer
  第79回日本寄生虫学会大会
- Place of Presentation
  旭川
- Year and Date
  2010-05-21
- Data Source
  KAKENHI-PROJECT-22390024
[Presentation] Proteome, analysis of schistosoma mansoni in the treatment of the infected animals with a new antischistosomal endoperoxide, N-892008
- Author(s)
  綿矢有佑
- Organizer
  8 th Awaji International Forum on Infection and Immunity
- Place of Presentation
  淡路
- Year and Date
  2008-09-09
- Data Source
  KAKENHI-PROJECT-19041049

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WATAYA Yusuke 綿矢 有佑

綿矢 祐佑 ワタヤ ユウスケ

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経皮吸収型抗マラリア薬開発のための基礎研究Principal Investigator

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Study of novel anti-leishmanial drugPrincipal Investigator

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Study of new broad spectrum of anti-parasitic agent and basis of molecular base of itPrincipal Investigator

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広範囲抗寄生虫薬の開発のための標的治療の分子基盤の確立Principal Investigator

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慢性疲労症候群診断法の開発と発症因子の探索Principal Investigator

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New antiamlarial drug development research including mechanism analysis of drug-resistant Plasmodium falciparumPrincipal Investigator

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RNA合成阻害を作用機序とする新規抗腫瘍薬3'-エチニルシチジンの分子標的の探索Principal Investigator

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新しい抗マラリア薬の開発と抗マラリア薬耐性機構の解析に関する研究Principal Investigator

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New Antimalarial Drug Research for Multidrug-resistant MalariaPrincipal Investigator

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WATAYA Yusuke 綿矢有佑

綿矢祐佑ワタヤユウスケ