KITA Eiji 喜多英二

Researcher Number	90133199
Other IDs
External Links
Affiliation (based on the past Project Information) *help	2011 – 2014: 奈良県立医科大学, 医学部, 教授 2001 – 2007: 奈良県立医科大学, 医学部, 教授 1999: 奈良県立医科大学, 医学部, 教授 1999: Nara Medical University, Bacteriology, Professor, 医学部・細菌学教室, 教授 1998: 奈良県立医科大学, 細菌学教室, 教授 1996: Nara Medical University, Dept.of Bacteriology, Professor, 医学部・細菌学, 教授 1995: 奈良県立医科大学, 医学部, 教授
Review Section/Research Field	Principal Investigator Bacteriology (including Mycology) / 内科学一般 / Public health/Health science / Respiratory organ internal medicine / 膠原病・アレルギー・感染症内科学 Except Principal Investigator Eating habits, studies on eating habits
Keywords	Principal Investigator 腸管出血性大腸菌 / Shiga toxin / ベロ毒素 / Gb3 / postinfection window / 脳症 / サイトカイン / BCG / HUS / apotosis … More / lipid raft / ghrelin / leptin / infection stress / shiga toxin-producing E. coli / 大腸菌 / アポトシス / 資質ラフト / グレリン / レプチン / 感染ストレス / intervention therapy / Encephalopathy / cytokines / PDE inhibitors / EHEC / フォスフォジエステラーゼ阻害剤 / インターベンション治療 / PDE阻害剤 / vascular endothelial damage / encephalopathy / apoptosis / IL-10 / TNF-α / malnutrition / enterohemorrhagic E.coli / 血管内皮傷害 / アポトーシス / 低栄養 / cellular immunity / L forms / intracellular parasite / tuberculosis / 免疫維持機構 / in situ PCR / マクロファージ / 抗酸菌感染症 / 細胞性免疫 / L型菌 / 細胞内寄生菌 / 結核 / リポ蛋白 / 中性糖セラミド / 腸管感染症 / 志賀毒素 / サーファクタント / 肺炎連鎖球菌 / 微生物接着 / ケモカイン / 粘膜炎症 / シンデカン / opsonin activity / cytokine / chemokine / surfactant / 気道感染 / 細菌性肺炎 / S.pneumoniae / MMP-7 / pneumonia / innate immunity / S.penumoniae / syndecan shedding / respiratory infection … More Except Principal Investigator リガンド / ナチュラルリガンド / インバリアントNKT細胞 / 構造 / スフィンゴ糖脂質 / 米糠 / Rice bran / Sphingoglycolipid / Natural ligand / Invariant NKT cell Less

LDL-dependent cytotoxicity of Shiga toxin in the cells devoid of Gb3Principal Investigator
- Principal Investigator
  
  KITA eiji
- Project Period (FY)
  2011 – 2013
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Bacteriology (including Mycology)
- Research Institution
  Nara Medical University
Identification of natural ligand for invariant NKT cells
- Principal Investigator
  
  EMOTO Masashi
- Project Period (FY)
  2010 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Eating habits, studies on eating habits
- Research Institution
  Gunma University
Enhanced activation of Gb3-bound Shiga toxin by leptin induced after infection with STEC O157Principal Investigator
- Principal Investigator
  
  KITA Eiji
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Bacteriology (including Mycology)
- Research Institution
  Nara Medical University
病原体の上皮細胞接着に対する初期応答が感染感受性を規定するPrincipal Investigator
- Principal Investigator
  
  喜多英二
- Project Period (FY)
  2003 – 2005
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  膠原病・アレルギー・感染症内科学
- Research Institution
  Nara Medical University
Intervention therapy for the prevention of hemolytic uremic syndrome (HUS) following STEC infectionPrincipal Investigator
- Principal Investigator
  
  KITA Eiji
- Project Period (FY)
  2001 – 2002
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  内科学一般
- Research Institution
  Nara Medical University
Analysis of the pathogenic mechanism of Shiga toxin-producing Escherichia coli infection for vaccine developmentPrincipal Investigator
- Principal Investigator
  
  KITA Eiji
- Project Period (FY)
  1998 – 1999
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Public health/Health science
- Research Institution
  Nara Medical University
Maintenance of acquired resistance to Mycobacterium tuberculosis by L form mycobacteria macrophagesPrincipal Investigator
- Principal Investigator
  
  KITA Eiji
- Project Period (FY)
  1995 – 1996
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Respiratory organ internal medicine
- Research Institution
  Nara Medical University

All 2014 2013 2012 2011 2008 2007 2006 2005 2004 2003 Other

All Journal Article Presentation Book

[Book] 細菌性腸管感染症の病態解析・診断・治療・疫学・予防に関する研究2007
- Author(s)
  喜多英二, 東伸岳, 岡山明子
- Total Pages
  6
- Publisher
  国際医学協力研究事業
- Data Source
  KAKENHI-PROJECT-18590434
[Book] Antibiotics as Anti-Inflammatories2004
- Author(s)
  Mikasa K., Kasahara K., Kita E.
- Total Pages
  14
- Publisher
  B.K.Rubin & J.Tamaoki
- Data Source
  KAKENHI-PROJECT-15659239
[Book] Syndecan shedding from epithelial cells affects host defense against respiratory infection2003
- Author(s)
  Kita E.
- Total Pages
  5
- Publisher
  Cong.Ser.
- Data Source
  KAKENHI-PROJECT-15659239
[Journal Article] Selective induction of antimicrobial peptides from keratinocytes by staphylococcal bacteria.2013
- Author(s)
  Ommori R, Ouji N, Mizuno F, Kita E, Ikada Y, Asada H.
- Journal Title
  
  Microb Pathog.
  
  Volume: 56 Pages: 35-39
- DOI
  10.1016/j.micpath.2012.11.005
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590515, KAKENHI-PROJECT-23591650
[Journal Article] Identification of a peptide-based neutralizer that potently inhibits both Shiga toxins 1 and 2 by targeting specific receptor- binding regions.2013
- Author(s)
  Watanabe-Takahashi M., Tsustuki K.　(contributed equally to this article)
- Journal Title
  
  Infection and Immunity
  
  Volume: 81 Issue: 6 Pages: 2133-2138
- DOI
  10.1128/iai.01256-12
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22790418, KAKENHI-PROJECT-23590515, KAKENHI-PROJECT-24390035
[Journal Article] Intranasal priming of newborn mice with microbial extracts increases opsonic factors and mature CD11c+ cells in the airway.2012
- Author(s)
  Kasahara K, Matsumura Y, Ui K, Kasahara K, Komatsu Y, Mikasa K, Kita E.
- Journal Title
  
  Am J Physiol Lung Cell Mol Physiol.
  
  Volume: 303 Issue: 9 Pages: L834-L843
- DOI
  10.1152/ajplung.00031.2012
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590515
[Journal Article] Enhanced expression of ABCA1 in non-rafts decreases the sensitivity of vascular endothelial cells to Shiga toxin2008
- Author(s)
  Mizuno F, Sugiura S, Kasahara K, Yasuda K, Kasahara K, Mikasa K, Kita, E
- Journal Title
  
  Infect. Immun (in press)
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590434
[Journal Article] Expression of inducible nitric oxide (NO) synthase but not preventio by its gene ablation of hepatocarcinogenesis with fibrosis caused b a choline-deficient, L-amino acid-defined diet in rats and mice.2007
- Author(s)
  Denda A, Kitayama Kita E, et al.
- Journal Title
  
  Nitric Oxide 16
  
  Pages: 164-176
- Data Source
  KAKENHI-PROJECT-18590434
[Journal Article] Expression of inducible nitric oxide(NO) synthase but not prevention by its gene ablation of hepatocarcinogenesis with fibrosis caused by a choline-deficient, L-amino acid-defined diet in rats and mice2007
- Author(s)
  Denda A, Kitayama, W, Kishida H, Murata N, Kita E, et. al.
- Journal Title
  
  Nitric Oxide 16
  
  Pages: 164-176
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590434
[Journal Article] A multivalent peptide-library approach identifies a novel Shiga toxin-inhibitor that induces aberrant cellular transport of the toxi2006
- Author(s)
  Nishikawa K, Watanabe M, Kita E, et al.
- Journal Title
  
  FASEB J. 20
- Data Source
  KAKENHI-PROJECT-18590434
[Journal Article] A multivalent peptide-library approach identifies a novel Shiga toxin-inhibitor that induces aberrant cellular transport of the toxin.2006
- Author(s)
  Nishikawa K, Watanabe M, Kita E, Igai K, Omata K, Yaffe B. M, Natori Y
- Journal Title
  
  FASEB J 20
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590434
[Journal Article] Favorable modification of macrolide-resistant Streptococcus pneumoniae infection in the lung by a 14-membered ring macrolide2006
- Author(s)
  Yasuki Yasuda, Kei Kasahara, Eiji Kita, et al.
- Journal Title
  
  J.Infect.Dis. (in press)
- Data Source
  KAKENHI-PROJECT-15659239
[Journal Article] Macrolide resistance of Streptococcus pneumoniae isolated during long term macrolide therapy : A difference between erythromycin and clarithromycin2005
- Author(s)
  Kasahara K, Kita K, et al.
- Journal Title
  
  J.Infect.Chemother In press
- NAID
  10015526209
- Data Source
  KAKENHI-PROJECT-15659239
[Journal Article] Clonal dissemination of macrolide resistant penicillin susceptible serotype 3 and penicillin resistant Taiwan 19F-14 and 23F-15 Streptococcus pneumoniae in Japan.2005
- Author(s)
  Kasahara K., Mikasa K., Konishi M., Maeda K., Kita E.et al.
- Journal Title
  
  J.Clin.Microbiol. 43
  
  Pages: 1640-1645
- Data Source
  KAKENHI-PROJECT-15659239
[Journal Article] Macrolide resistance of Streptococcus pneumoniae isolated during long term macrolide therapy : A difference between erythromycin and clarithromycin2005
- Author(s)
  Kasahara K, Kita E, Maeda K, et al.
- Journal Title
  
  J.Infect.Chemother. 11
  
  Pages: 112-114
- NAID
  10015526209
- Data Source
  KAKENHI-PROJECT-15659239
[Journal Article] Clonal dissemination of macrolide resistant penicillin susceptible serotype 3 and penicillin resistant Taiwan 19F-14 and 23F-15 Streptococcus pneumoniae in Japan2005
- Author(s)
  Kasahara K, Kita E, et al.
- Journal Title
  
  J.Clin.Microbiol. In press
- Data Source
  KAKENHI-PROJECT-15659239
[Journal Article] Subcutaneous vaccination of Mycobacterium bovis Bacillus Calmette-Guerin (BCG) attenuates allergic inflammation in a murine model of asthma2005
- Author(s)
  Ito T, Hamada K, Suzaki Y, Matsui N, Kita E, Kimura H.
- Journal Title
  
  Allergy International 54
  
  Pages: 601-609
- Data Source
  KAKENHI-PROJECT-15659239
[Journal Article] Long-term azithromycin therapy for three patients with chronic lower respiratory tract infections.2004
- Author(s)
  Kasahara K., Mikasa K., Konishi M., Maeda K., Kita E.et al.
- Journal Title
  
  J.Infect.Chemother. 10
  
  Pages: 42-45
- NAID
  10016521124
- Data Source
  KAKENHI-PROJECT-15659239
[Journal Article] Long-term azithromycin therapy for three patients with chronic lower respiratory tract infections2004
- Author(s)
  Kasahara K., Kita E.et al.
- Journal Title
  
  J.Infect.Chemother 10
  
  Pages: 42-45
- NAID
  10016521124
- Data Source
  KAKENHI-PROJECT-15659239
[Journal Article] Syndecan shedding from epithelial cells affects host defense against respiratory infection.2003
- Author(s)
  Kita E.
- Journal Title
  
  Int.Cong.Ser. 1257
  
  Pages: 21-26
- Data Source
  KAKENHI-PROJECT-15659239
[Presentation] 神経細胞でのABCA1発現低下と志賀毒素活性の変化2014
- Author(s)
  東伸岳、松村羊子、水野文子、喜多英二
- Organizer
  奈良県感染症研究会
- Place of Presentation
  奈良
- Year and Date
  2014-01-12
- Data Source
  KAKENHI-PROJECT-23590515
[Presentation] LDL受容体を介する志賀毒素の取り込み2013
- Author(s)
  喜多英二、東伸岳、水野文子
- Organizer
  近畿感染症研究会
- Place of Presentation
  大阪
- Year and Date
  2013-06-17
- Data Source
  KAKENHI-PROJECT-23590515
[Presentation] 志賀毒素と特異受容体Gb3及びLDLの関連解析2011
- Author(s)
  笠原一規、東伸岳、下嶋典子、喜多英二
- Organizer
  日本細菌学会関西支部総会
- Place of Presentation
  大阪
- Year and Date
  2011-11-17
- Data Source
  KAKENHI-PROJECT-23590515
[Presentation] 「志賀毒素の受容体Gb3非発現細胞での毒性機序」2011
- Author(s)
  喜多英二　他
- Organizer
  畿腸管感染症研究会
- Place of Presentation
  大阪
- Data Source
  KAKENHI-PROJECT-23590515
[Presentation] ABCA1発現低下と志賀毒素による血管内皮障害機構2011
- Author(s)
  東伸岳、松村羊子、喜多英二
- Organizer
  日本細菌学会関西支部総会
- Place of Presentation
  大阪
- Year and Date
  2011-11-19
- Data Source
  KAKENHI-PROJECT-23590515
[Presentation] 志賀毒素の受容体Gb3非発現細胞での毒性機序2011
- Author(s)
  喜多英二、松村羊子、東伸岳、水野文子
- Organizer
  近畿腸管感染症研究会
- Place of Presentation
  大阪
- Year and Date
  2011-06-18
- Data Source
  KAKENHI-PROJECT-23590515
[Presentation] Enhancement of STEC-related encephalopathy by increased NO production2007
- Author(s)
  Higashi N, Nishikawa F, Ouji N, Katsui N, Kita, E
- Organizer
  Jp. Soc. For Bacteriology
- Place of Presentation
  Annual Meeting
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590434
[Presentation] Phosphodiesterase IV inhibitors redued sensitivity to Shiga toxin of vascular endothelial cells2007
- Author(s)
  Ohji N, Okayama A, Higashi N, Yasuda Y, Kita, E
- Organizer
  Jp. Soc. For Bacteriology, Kansai Local Meeting
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590434
[Presentation] 志賀毒素による脳症発症機構2006
- Author(s)
  喜多英二
- Organizer
  日米コレラ日本総会
- Place of Presentation
  東京
- Year and Date
  2006-08-18
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18590434
[Presentation] Cellular factors involved in vascular damage by Shiga toxin2006
- Author(s)
  Okayama A, Higashi N, Mizuno F, Kita, E
- Organizer
  EHEC Symposium
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590434
[Presentation] Mechanism of acute encephalopathy by Shiga toxin2006
- Author(s)
  Kita, E
- Organizer
  U.S.-Japan Joint Conference of Cholera
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590434
[Presentation] LDL受容体を介する志賀毒素の取り込み
- Author(s)
  喜多英二　他
- Organizer
  近畿腸管感染研究会
- Place of Presentation
  大阪
- Data Source
  KAKENHI-PROJECT-23590515

1. MIZUNO Fumiko (70271202)

# of Collaborated Projects: 4 results

# of Collaborated Products: 6 results
2. EMOTO Masashi (70232981)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
3. NAIKI Yoshikazu (10434622)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
4. FUJIMURA Takao (50209087)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
5. FUKUDA Toshio (00173352)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. SAGESHIMA Noriko (30398432)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. 三笠桂一 (80209725)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. 前田光一 (30295795)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. EMOTO Yoshiko

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. WATANABE Kazuki

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. KOYAMA Yu-ichi

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. NYU Kiyosato

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
13. KIYAMA Takajyu

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
14. NISHIO Kazumasa

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
15. HURWITZ Robert

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
16. KAUFMANN Stefan H.E.

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
17. MOLLENKOPF Hans

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
18. TAKAHASHI Miho

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
19. 王寺典子

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results

KITA Eiji 喜多 英二

Research Projects

Research Products

Co-Researchers

LDL-dependent cytotoxicity of Shiga toxin in the cells devoid of Gb3Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Identification of natural ligand for invariant NKT cells

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Enhanced activation of Gb3-bound Shiga toxin by leptin induced after infection with STEC O157Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

病原体の上皮細胞接着に対する初期応答が感染感受性を規定するPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Intervention therapy for the prevention of hemolytic uremic syndrome (HUS) following STEC infectionPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Analysis of the pathogenic mechanism of Shiga toxin-producing Escherichia coli infection for vaccine developmentPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Maintenance of acquired resistance to Mycobacterium tuberculosis by L form mycobacteria macrophagesPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Book] 細菌性腸管感染症の病態解析・診断・治療・疫学・予防に関する研究2007

Author(s)

Total Pages

Publisher

Data Source

[Book] Antibiotics as Anti-Inflammatories2004

Author(s)

Total Pages

Publisher

Data Source

[Book] Syndecan shedding from epithelial cells affects host defense against respiratory infection2003

Author(s)

Total Pages

Publisher

Data Source

[Journal Article] Selective induction of antimicrobial peptides from keratinocytes by staphylococcal bacteria.2013

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Identification of a peptide-based neutralizer that potently inhibits both Shiga toxins 1 and 2 by targeting specific receptor- binding regions.2013

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Intranasal priming of newborn mice with microbial extracts increases opsonic factors and mature CD11c+ cells in the airway.2012

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Enhanced expression of ABCA1 in non-rafts decreases the sensitivity of vascular endothelial cells to Shiga toxin2008

Author(s)

Journal Title

Description

KITA Eiji 喜多英二