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HASUO Hiroshi  蓮尾 博

ORCIDConnect your ORCID iD *help
Researcher Number 90172882
Other IDs
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Affiliation (based on the past Project Information) *help 2008 – 2010: Kurume University, 医学部, 准教授
2005 – 2006: 久留米大学, 医学部, 助教授
2002 – 2003: 久留米大学, 医学部, 助教授
1995 – 1998: 久留米大学, 医学部, 助教授
1989 – 1991: 久留米大学, 医学部, 講師
Review Section/Research Field
Principal Investigator
神経・脳内生理学 / Neurophysiology and muscle physiology / Cerebral neurosurgery
Except Principal Investigator
Neurophysiology and muscle physiology / Neurophysiology and muscle physiology / 神経・脳内生理学 / General physiology
Keywords
Principal Investigator
長期増強 / IPSP / 修飾作用 / induction / lateral septum / GABA_B / EPSP / interneuron / GABA receptor / LTP … More / 細胞内電位記録 / 介在ニューロン / GABA_B受容体 / GABA受容体 / 抑制性シナプス後電位 / 外側中隔核 / 脳スライス標本 / Long-term potentiation / Metabotropic glutamate receptor / Modulation / Synaptic transmission / Excitatory amino acid / Patch-clamp / Septal nuclei / Central nervous system / 伝達修飾作用 / 代謝型グルタミン酸受容体 / シナプス伝達 / 興奮性アミノ酸受容体 / スライスパッチ / 中隔核 / 中枢神経系 / 大黄(だいおう) / エモジン / 海馬核 / 脳損傷 / 液体打撃法 / 頭部外傷モデル動物 / 神経科学 / 生理学 / 薬理学 / 脳・神経 / 神経保護薬 / 頭部外傷学 … More
Except Principal Investigator
EPSP / Suprachiasmatic nucleus / 細胞内電極法 / memory disturbance / epilepsy / NO scavengers / diazepam / glutamate neurons / hippocampal CA1 / dentate gyrus / brain injury / ガンマーアミノ酪酸 / グルタミン酸 / 興奮性シナプス伝達 / 頭部外傷モデル / 記憶障害 / てんかん / 抑制性シナプス伝達 / NO除去効果 / グルタミン酸作動性神経 / ジアゼパム / 歯状回及び海馬CA1領域 / 脳外傷後遺症 / excitatory synaptic transmission / whole-cell patch-clamp recordings / long-term potentiation (LTP) / post-traumatic excitation / hippocampal slice preparation / experimental head injury model rat / post-traumatic epilepsy / パッチクランプ法 / 細胞外電極法 / 光学的電位記録法 / 海馬スライス標本 / 実験的脳外傷モデルラット / 外傷後てんかん / presynaptic modulation / GABA / long-lasting hyperpolarization / depolarization / sympathetic ganglia / pelvic ganglia / interleukin-1beta / cytokine / 交感神経節 / 骨盤内神経叢 / インターロイキン / ストレス / 自律神経機能 / 大脳中隔核 / 細胞内シグナル伝達機構 / シナプス伝達 / 骨盤神経叢 / 1L-1β活性フラグメント / インターロイキン-1β / GABA_B受容体 / G-蛋白 / パッチクランプ / γ-アミノ酪酸 / 自律神経節 / シナプス前調節機構 / グアニル酸シクラーゼ / 中隔核 / 過分極電位 / サイトカイン / IL-1β / 副交換神経節 / 交換神経節 / Dorsolateral septal nucleus / Sympathetic neurons / Primary afferent neurons / Ionic currents / Phosporylation / Calmodulin / Cyclic AMP / Adenylate cyclase / 遅延整流 / ハロセン / プロテインカイネ-ス / フォ-スコリン / アデニレ-ト・サイクラ-ゼ / パッチ・クランプ / 脊椎動物 / 背外側中隔核 / 背外側中隔核細胞 / 自律神経節細胞 / M電流 / H電流 / リン酸化 / カルモジュリン / Cキナ-ゼ / アデニレ-トサイクラ-ゼ / IPSP / Low-threshold Ca-current / Inward rectification / Spontaneous activity / Intracellular recordings / Electrophysiology / ソマトスチタン / バゾプレッシン / 脳スライス標本 / 細胞内微小電極法 / 静止・活動電位 / 視交叉上核 / Metabotropic receptors / PIーturn over / Circadian rhythm / Central nervous system / Rat / 抑制性シナプス後電位 / 興奮性シナプス後電位 / カルシウム電流 / Hー電流 / 内向き整流 / 自発性活動電位 / ラット視交叉上核 Less
  • Research Projects

    (8 results)
  • Research Products

    (27 results)
  • Co-Researchers

    (4 People)
  •  Exploring a novel neuroprotectant for the treatment of acute traumatic brain injury using experimental model ratsPrincipal Investigator

    • Principal Investigator
      HASUO Hiroshi
    • Project Period (FY)
      2008 – 2010
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Cerebral neurosurgery
    • Research Institution
      Kurume University
  •  Contribution of neuronal regeneration in the hippocampus and dentate gyrus to the memory disturbance after traumatic brain injury

    • Principal Investigator
      AKASU Takashi
    • Project Period (FY)
      2005 – 2006
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Neurophysiology and muscle physiology
    • Research Institution
      Kurume University
  •  Analysis of experimental brain injury on long-term potentiation of hippocampal neurons of the rat

    • Principal Investigator
      AKASU Takashi
    • Project Period (FY)
      2002 – 2003
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      神経・脳内生理学
    • Research Institution
      KURUME UNIVERSITY
  •  Effects of interleukin-1beta on neurons in mammalian parasympathetic ganglia.

    • Principal Investigator
      AKASU Takashi
    • Project Period (FY)
      1996 – 1998
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      General physiology
    • Research Institution
      Kurume University
  •  Long-term potentiation of inhibitory postsynaptic potentials in rat lateral septal nucleus neuronsPrincipal Investigator

    • Principal Investigator
      HASUO Hiroshi
    • Project Period (FY)
      1995 – 1996
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      神経・脳内生理学
    • Research Institution
      Kurume University
  •  Modulation of synaptic transmission in rat septal nucleus neuronsPrincipal Investigator

    • Principal Investigator
      TOKIMASA Takayuki, 蓮尾 博
    • Project Period (FY)
      1991 – 1992
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      Neurophysiology and muscle physiology
    • Research Institution
      Kurume University
  •  Ionic currents of vertebrate nerve cells regulated by adenylate cyclase

    • Principal Investigator
      TOKIMASA Takayuki
    • Project Period (FY)
      1990 – 1991
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      Neurophysiology and muscle physiology
    • Research Institution
      Kurume University
  •  Analysis of electrophysiological properties and transmissions in rat suprachiasmatic nucleus neurons

    • Principal Investigator
      AKASU Takashi
    • Project Period (FY)
      1989 – 1991
    • Research Category
      Grant-in-Aid for General Scientific Research (B)
    • Research Field
      Neurophysiology and muscle physiology
    • Research Institution
      Kurume University

All 2011 2010 2009 2008 2007 2006 2005

All Journal Article Presentation

  • [Journal Article] Edaravone attenuates impairment of synaptic plasticity in granule cell layer of the dentate gyrus following traumatic brain injury.2011

    • Author(s)
      Yamashita S, Hasuo H, Tokutomi T, Shigemori M, Akasu T
    • Journal Title

      Kurume Med J 58(印刷中)

    • NAID

      130002097076

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20591698
  • [Journal Article] Isolated guinea pig seminal vesicle contracts in response to mechanical stimuli without the activities of neurons and Kit-positive interstitial cells.2011

    • Author(s)
      Takeya M,, Hayashi T, Ishimatsu M, Nakamura K, Hasuo H
    • Journal Title

      J Physiol Sci 61

    • Data Source
      KAKENHI-PROJECT-20591698
  • [Journal Article] Emodin, an active compound of Chinese medicine, attenuates the impairment of LTP after moderate traumatic brain injury (TBI) in rats.2010

    • Author(s)
      蓮尾博, 武谷三恵
    • Journal Title

      Neurosci Res 68

    • Data Source
      KAKENHI-PROJECT-20591698
  • [Journal Article] Emodin attenuates the impairment of LTP after traumatic brain injury in rat hippocampus.2009

    • Author(s)
      Takeya M, Hasuo H, Akasu T
    • Journal Title

      Neurosci Res 65

    • Data Source
      KAKENHI-PROJECT-20591698
  • [Journal Article] Impairment of LTP in hippocampal neurons of the traumatic brain injury model rats and its attenuation by neuroprotective drugs.2009

    • Author(s)
      Hasuo H, Takeya M, Ooba S, Yamashita S, Akasu T
    • Journal Title

      J Physiol Sci 59

      Pages: 366-366

    • Data Source
      KAKENHI-PROJECT-20591698
  • [Journal Article] ラット海馬CA1ニューロンにおける脳外傷後過興奮とジアゼパムの効果.2009

    • Author(s)
      大場さとみ,山下伸,蓮尾博,徳富孝志,赤須崇,重森稔
    • Journal Title

      神経外傷 32

      Pages: 61-67

    • NAID

      10027501396

    • Data Source
      KAKENHI-PROJECT-20591698
  • [Journal Article] 中隔核における5-HT_<1B>受容体の役割2009

    • Author(s)
      蓮尾博
    • Journal Title

      生体の科学 60

      Pages: 430-431

    • Data Source
      KAKENHI-PROJECT-20591698
  • [Journal Article] 医学生が階層的に活用できる腸管運動の動画教材の作成.2009

    • Author(s)
      武谷三恵,林篤正,石松秀,蓮尾博,赤須崇
    • Journal Title

      医教育 40

      Pages: 89-89

    • Data Source
      KAKENHI-PROJECT-20591698
  • [Journal Article] 中隔核における5-HT1B受容体の役割.2009

    • Author(s)
      蓮尾博,赤須崇
    • Journal Title

      生体の科学 60

      Pages: 430-431

    • Data Source
      KAKENHI-PROJECT-20591698
  • [Journal Article] Mild hypothermia prevents post-traumatic hyperactivity of excitatory synapses in rat hippocampal CA1 pyramidal neurons.2009

    • Author(s)
      Ooba S, Hasuo H, Shigemori M, Yamashita S, Akasu T
    • Journal Title

      Kurume Med J 56

      Pages: 49-59

    • NAID

      130000259041

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20591698
  • [Journal Article] The radical scavenger edaravone suppresses the exogenous nitric oxide [NO]-induced potentiation of perforant path synapse of the dentate gyrus in vitro.2008

    • Author(s)
      Hasuo H, Yamashita S, Shigemori M, Akasu T
    • Journal Title

      Neurosci Res 61

    • Data Source
      KAKENHI-PROJECT-20591698
  • [Journal Article] Diazepam attenuates the post-traumatic hyperactivity of excitatory synapses in rat hippocampal CA1 neurons.2008

    • Author(s)
      Ooba S, Hasuo H, Shigemori M, Akasu T
    • Journal Title

      Neurosci Res 62

      Pages: 195-205

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20591698
  • [Journal Article] Dopamine induced long-lasting enhancement of the EPSP in rat dorsolateral septal nucleus neurons2007

    • Author(s)
      Hasuo H
    • Journal Title

      J Physiol Sci 57(Suppl)

    • NAID

      130007038587

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-17500279
  • [Journal Article] Dopamine induced long-lasting enhancement of the EPSP in rat dorsolateral septal nucleus neurons2007

    • Author(s)
      Hasuo H
    • Journal Title

      J Physiol Sci 57-Suppl

    • NAID

      130007038587

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17500279
  • [Journal Article] Facilitation of glutamatergic excitatory synaptic transmission in hippocampal CA1 regions of traumatic brain injury model rats2006

    • Author(s)
      Hasuo H
    • Journal Title

      J Physiol Sci 56-Suppl

    • NAID

      130005448421

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17500279
  • [Journal Article] Facilitation of glutamatergic excitatory synaptic transmission in hippocampal CA1 regions of traumatic brain injury model rats2006

    • Author(s)
      Hasuo H
    • Journal Title

      J Physiol Sci 56(Suppl)

    • NAID

      130005448421

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-17500279
  • [Journal Article] Activation of adenosine Ai receptors contributes to the depression of EPSPs induced by emodin in rat hippocampal CA1 pyramidal neurons in vitro2005

    • Author(s)
      Hasuo H
    • Journal Title

      Neurosci Res 52-Suppl

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17500279
  • [Journal Article] Contribution of endogenous adenosine to the effect of emodin on the excitatory synaptic transmission in rat hippocampal CA1 pyramidal neurons in vitro2005

    • Author(s)
      Hasuo H
    • Journal Title

      The Fifth Japan-Korea Joint Symposium of Brain Sciences, and Cardiac and Smooth Muscles Program & Abstracts

      Pages: 37-37

    • Data Source
      KAKENHI-PROJECT-17500279
  • [Journal Article] Contribution of endogenous adenosine to the effect of emodin on the excitatory synaptic transmission in rat hippocampal CA1 pyramidal neurons in vitro2005

    • Author(s)
      Hasuo H
    • Journal Title

      The Fifth Japan-Korea Joint Symposium of Brain Sciences, and Cardiac and Smooth Muscles Program & Abstracts

      Pages: 37-37

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-17500279
  • [Journal Article] Activation of adenosine A_1 receptors contributes to the depression of EPSPs induced by emodin in rat hippocampal CA1 pyramidal neurons in vitro2005

    • Author(s)
      Hasuo H
    • Journal Title

      Neurosci Res 52(Suppl)

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-17500279
  • [Presentation] Emodin, an active compound of Chinese medicine, attenuates the impairment of LTP after moderate traumatic brain injury (TBI) in rats.2010

    • Author(s)
      蓮尾博
    • Organizer
      The 33rd Annual Meeting of the Japan Neuroscience Society (Neuro 2010)
    • Place of Presentation
      神戸
    • Year and Date
      2010-09-04
    • Data Source
      KAKENHI-PROJECT-20591698
  • [Presentation] Impairment of LTP in hippocampal neurons of the traumatic brain injury model rats and its attenuation by neuroprotective drugs2009

    • Author(s)
      Hasuo H
    • Organizer
      The XXXVI IUPS2009・The 86th Annual Meeting of the Physiological Society of Japan
    • Place of Presentation
      京都
    • Year and Date
      2009-07-30
    • Data Source
      KAKENHI-PROJECT-20591698
  • [Presentation] Impairment of LTP in hippocampal neurons of the traumatic brain injury model rats and its attenuation by neuroprotective drugs. The XXXVI International Congress of Physiological Sciences (IUPS2009)2009

    • Author(s)
      蓮尾博
    • Organizer
      The 86th Annual Meeting of the Physiological Society of Japan
    • Place of Presentation
      京都
    • Year and Date
      2009-07-30
    • Data Source
      KAKENHI-PROJECT-20591698
  • [Presentation] 頭部外傷後のシナプス可塑性障害に対するエダラボンの効果.2008

    • Author(s)
      蓮尾博
    • Organizer
      生理学研究所研究会「新たなコンセプトでシナプス伝達機構を考える」
    • Place of Presentation
      岡崎
    • Year and Date
      2008-09-20
    • Data Source
      KAKENHI-PROJECT-20591698
  • [Presentation] The radical scavenger edaravone suppresses the exogenous nitric oxide [NO]-induced potentiation of perforant path synapse of the dentate gyrus in vitro.2008

    • Author(s)
      蓮尾博
    • Organizer
      The 31st Annual Meeting of the Japan Neuroscience Society (Neuro2008)
    • Place of Presentation
      東京
    • Year and Date
      2008-07-11
    • Data Source
      KAKENHI-PROJECT-20591698
  • [Presentation] The radical scavenger edaravone suppresses the exogenous nitric oxide[NO]-induced potentiation of perforant path synapse of the dentate gyrus in vitro.2008

    • Author(s)
      Hasuo H
    • Organizer
      The 31st Annual Meeting of the Japan Neuroscience Society
    • Place of Presentation
      東京
    • Year and Date
      2008-07-11
    • Data Source
      KAKENHI-PROJECT-20591698
  • [Presentation] 頭部外傷後のシナプス可塑性障害に対するエダラボンの効果2008

    • Author(s)
      蓮尾博
    • Organizer
      平成20年度生理学研究所研究会『新たなコンセプトでシナプス伝達機構を考える』
    • Place of Presentation
      岡崎
    • Year and Date
      2008-09-20
    • Data Source
      KAKENHI-PROJECT-20591698
  • 1.  AKASU Takashi (60113213)
    # of Collaborated Projects: 4 results
    # of Collaborated Products: 0 results
  • 2.  TOKIMASA Takayuki (50155511)
    # of Collaborated Projects: 4 results
    # of Collaborated Products: 0 results
  • 3.  TAKEYA Mitsue (30289433)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 5 results
  • 4.  TSURUSAKI Masashi (60207454)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results

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