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MATSUMOTO Yoh  松本 陽

ORCIDConnect your ORCID iD *help
… Alternative Names

松本 陽  マツモト ヨウ

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Researcher Number 90173921
Other IDs
External Links
Affiliation (based on the past Project Information) *help 2014: 公益財団法人東京都医学総合研究所, 運動・感覚システム研究分野, 研究員
2011: 財団法人東京都医学総合研究所, 認知症・高次脳機能研究分野, 研究員
2010: (財)東京都医学研究機構, 東京都神経科学総合研究所, 特任研究員
2009: 財団法人東京都医学研究機構, 東京都神経科学総合研究所, 参事研究員
2005 – 2006: (財)東京都医学研究機構, 東京都神経科学総合研究所, 参事研究員 … More
2003: (財)東京都医学研究機構, 東京都神経科学総合研究所, 参事研究員
2001 – 2002: 財団法人東京都医学研究機構, 東京都神経科学総合研究所, 参事研究員
2001: Tokyo Metropolitan Inst. for Neurosci., 東京都神経科学総合研究所, 参事研究員
2000: Tokyo Metropolitan Inst. for Neurosci., 東京都神経科学総合研究所・神経病理研究部門, 参事研究員
1999: Tokyo Metropolitan Inst. for Neurosci., 東京都神経科学総合研究所, 参事研究員
1999: 財団法人 東京都医学研究機構, 東京都神経科学総合研究所, 参事研究員
1998: 東京都神経科学総合研究所, 神経病理学研究部門, 副参事研究員
1998: Tokyo Metropolitan Institute for Neuroscience, 神経病理研究部門, 副参事研究員
1995 – 1998: (財)東京都神経科学総合研究所, 神経病理研究部門, 副参事研究員
1997: Tokyo Metropolitan Inst.for Neurosci., 神経病理学研究部門, 副参事研究員
1996 – 1997: (財)東京都神経科学総合研究所, 神経病理学研究部門, 副参事研究員
1995: Tokyo Metropolitan Institute for Neuroscience, Department of Neuropathology, Director, 神経病理研究部門, 副参事研究員
1994: (財)東京都神経科学総合研究所, 神経病理学研究部門, 副参事研究員
1992: 新潟大学, 医学部, 講師 Less
Review Section/Research Field
Principal Investigator
Neurology / Nerve anatomy/Neuropathology
Except Principal Investigator
Neurology / Neurology / Nerve anatomy/Neuropathology
Keywords
Principal Investigator
in situ RT-PCR / DNAワクチン / Central nervous system / STAT / Autoimmune encephalomyelitis / サイトカイン / 自己免疫性脳脊髄炎 / T細胞レセプター / 免疫性神経疾患 / DNA avaccine … More / CDR3 spectratyping / T cell receptor / Autoimmune disease / CDR3領域スペクトラタイピング / In situ hybridization / Glia / Cytokine / Competitive PCR / インサイチュウハイブリダイゼーション / グリア細胞 / 競合PCR / 中枢神経 / Quantitative PCR / Cytokines / Neural graft / quantitative PCR / competitive PCR / 神経移植 / DNAワクチン療法 / Aβ / アルツハイマー病 … More
Except Principal Investigator
DNAワクチン / DNA vaccine / T cell receptor / T細胞レセプター / interleukin 10 / EAE / Cytokine / サイトカイン / in situ RT-PCR / Aベータ / アルツハイマー病 / therapy / Alzheimer's disease / 治療 / C-protein / myositogenic antigen / polymositis / C蛋白 / 筋炎惹起抗原 / 自己免疫性筋炎 / Spinal cord / Motor neuron disease / Motoneuron / Gene therapy / GDNF / Facial nerve / Avulsion / Adenovirus / 成熟ラット / 脊髄損傷 / 脊髄運動ニューロン / グリア細胞株由来神経栄養因子(GDNF) / グリア細胞株由来神経栄養因子(GDんF) / 運動ニューロン疾患 / 成体ラット / 運動神経損傷 / 運動ニューロン / 遺伝子治療 / アデノウイルスベクター / 神経栄養因子 / CDR3 spectrayping / myositogenic T cells / polymyositis / スペクトラタイピング / 筋炎惹起性T細胞 / 多発性筋炎 / transforming growth factor beta1 / interferon gamma / tumor necrosis factor alpha / Competitive PCR / サイクロスポリンA / competitivePCR / Interleukin-10 / Transforming growth factor-β1 / interferon-γ / Tumor necrosis factor / transforming growth factor β1 / interferon γ / tumor necrosis factor α / competitive PCR / encephalomyelitis / Experimental autoimmune / 自己免疫性脳脊髄炎 / タウ / アミロイドβ / アルツハイマー病治療 / 胸腺萎縮 / 1L-2R_β / αβT細胞 / 肝類洞 / 胸腺外T細胞 Less
  • Research Projects

    (14 results)
  • Research Products

    (16 results)
  • Co-Researchers

    (18 People)
  •  Generation of new DNA vaccine plasmid for the therapy of Alzheimer's disease

    • Principal Investigator
      KOHYAMA Kuniko
    • Project Period (FY)
      2012 – 2014
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Neurology
    • Research Institution
      Tokyo Metropolitan Institute of Medical Science
  •  Development of a new and effective DNA vaccine for Alzheimer's disease

    • Principal Investigator
      OKURA Yosio
    • Project Period (FY)
      2009 – 2011
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Neurology
    • Research Institution
      財団法人東京都医学総合研究所
      Tokyo Metropolitan Organization for Medical Research
  •  Development of non-viral A beta DNA vaccines against Alzheimer's disease

    • Principal Investigator
      OKURA Yoshio
    • Project Period (FY)
      2005 – 2006
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Neurology
    • Research Institution
      Tokyo Metropolitan Organization for Medical Research
  •  アルツハイマー病モデルの治療に有効なAβ・DNAワクチンの創製Principal Investigator

    • Principal Investigator
      松本 陽
    • Project Period (FY)
      2002 – 2003
    • Research Category
      Grant-in-Aid for Exploratory Research
    • Research Field
      Neurology
    • Research Institution
      Tokyo Metropolitan Organization for Medical Research
  •  Analysis on pathogenesis of experimetnal autoimmune polymyositis and development of gene thrapy

    • Principal Investigator
      KOHYAMA Kuniko
    • Project Period (FY)
      2000 – 2001
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Neurology
    • Research Institution
      Tokyo Metropolitan Institute for Neuroscience
  •  免疫性神経疾患の予防・治療に有効な遺伝子ワクチンの創製Principal Investigator

    • Principal Investigator
      松本 陽
    • Project Period (FY)
      1998 – 2000
    • Research Category
      Grant-in-Aid for Exploratory Research
    • Research Field
      Neurology
    • Research Institution
      Tokyo Metropolitan Organization for Medical Research
  •  Characterization of T cell receptor (TCR) of neurological autoimmune disease-inducing T cells and TCR-based immunotherapy with DNA vaccinesPrincipal Investigator

    • Principal Investigator
      MATSUMOTO Yoh
    • Project Period (FY)
      1998 – 2000
    • Research Category
      Grant-in-Aid for Scientific Research (A).
    • Research Field
      Neurology
    • Research Institution
      Tokyo metropolitan Institute for Neuroscience
      Tokyo Metropolitan Institute for Neuroscience
  •  Adenoviral GDNF gene therapy against motoneuron death

    • Principal Investigator
      WATABE Kazuhiko
    • Project Period (FY)
      1998 – 1999
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Neurology
    • Research Institution
      TOKYO METROPOLITAN ORGANIZATION FOR MEDICAL RESEARCH
      Tokyo Metropolitan Institute for Neuroscience
  •  Role of cytokines in the lesion repair in the central nervous systemPrincipal Investigator

    • Principal Investigator
      MATSUMOTO Yoh
    • Project Period (FY)
      1997 – 1999
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Nerve anatomy/Neuropathology
    • Research Institution
      Tokyo Metropolitan Institute for Neuroscience
  •  Analysis of experimental autoimmune myositis and its immunotherapy

    • Principal Investigator
      KOJIMA Takashi
    • Project Period (FY)
      1997 – 1998
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Neurology
    • Research Institution
      Tokyo Metropolitan Institute for Neuroscience
  •  Quantitative analysis of cytokine mRNA in neuroimmunological disorders.

    • Principal Investigator
      TANUMA Naoyuki
    • Project Period (FY)
      1996 – 1997
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Nerve anatomy/Neuropathology
    • Research Institution
      Tokyo Metropolitan Institute for Neuroscience
  •  Semiquantification and localization of brain cytokine by in situ RT-PCR

    • Principal Investigator
      KAWAZOE Yoko, 石原 好弘
    • Project Period (FY)
      1995 – 1996
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Nerve anatomy/Neuropathology
    • Research Institution
      Tokyo Metropolitan Institute for Neuroscience
  •  The role of cytokines in autoimmune encephalomyelitis and rejection processes of neural graftsPrincipal Investigator

    • Principal Investigator
      MATSUMOTO Yoh
    • Project Period (FY)
      1994 – 1995
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      Nerve anatomy/Neuropathology
    • Research Institution
      Tokyo Metropolitan Institute for Neuroscience
  •  肝類洞で起こる胸腺外T細胞分化経路の抗腫瘍免疫で果たす役割

    • Principal Investigator
      安保 徹
    • Project Period (FY)
      1992
    • Research Category
      Grant-in-Aid for Cancer Research
    • Research Institution
      Niigata University

All 2015 2011 2010 2009 2006 2005

All Journal Article Presentation Patent

  • [Journal Article] Alzheimer’s disease and immunotherapy: what is wrong with clinical trials?2015

    • Author(s)
      Kohyama K, Matsumoto Y
    • Journal Title

      ImmunoTargets and Therapy

      Volume: 4 Pages: 27-27

    • DOI

      10.2147/itt.s49923

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-24591283
  • [Journal Article] Assessment of non-viral AβDNA vaccines on Aβreduction and safety in rhesus monkeys2010

    • Author(s)
      Tokita Y, Kaji K, Lu J, Okura Y, Kohyama K, Matsumoto Y
    • Journal Title

      J Alzheimer Dis

      Volume: 22 Pages: 1351-1361

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21591103
  • [Journal Article] Assessment of non-viral Aβ DNA vaccines on Aβ reduction and safety in rhesus monkeys2010

    • Author(s)
      Tokita Y, Kaji K, Lu J, Okura Y, Kohyama K, Matsumoto Y.
    • Journal Title

      J Alz Dis

      Volume: 22 Pages: 1351-1361

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21591103
  • [Journal Article] アルツハイマー病に対するワクチン療法2009

    • Author(s)
      大倉良夫、松本陽
    • Journal Title

      バイオ医薬の開発技術とシーズ

      Pages: 31-364

    • Data Source
      KAKENHI-PROJECT-21591103
  • [Journal Article] Alzheimer病のワクチン療法の現状2009

    • Author(s)
      大倉良夫、松本陽
    • Journal Title

      医学の歩み

      Volume: 229 Pages: 220-221

    • Data Source
      KAKENHI-PROJECT-21591103
  • [Journal Article] Recent advance in immunotherapies for Alzheimer's disease, with special reference to DNA vaccination2009

    • Author(s)
      Okura, Y., Matsumoto, Y
    • Journal Title

      Human Vaccine

      Volume: 5 Pages: 3-10

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21591103
  • [Journal Article] Matrix metalloproteinase(MMP)-9, but not MMP-2, is involved in the development and progression of C-protein-induced myocarditis and subsequent dilated cardiomyopathy2009

    • Author(s)
      Matsumoto, Y, Park, I., Kohyama, K.
    • Journal Title

      J Immunol 183

      Pages: 4773-4781

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21591103
  • [Journal Article] Non-viral A beta DNA vaccine therapy against Alzheimer's disease : Long term-effects and safety2006

    • Author(s)
      Okura, Y., Miyakoshi, A., Kohyama, K., Staufenbiel, M., Matsumoto, Y
    • Journal Title

      Proc. Natl. Acad. Sci. USA 103

      Pages: 9619-9624

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-17590909
  • [Journal Article] Non-viral A beta DNA vaccine therapy against Alzheimer's disease : Long term-effects and safety2006

    • Author(s)
      Okura, Y., Miyakoshi, A., Kohyama, K., Staufenbiel, M., Matsumoto, Y
    • Journal Title

      Proc.Natl.Acad.Sci.USA 103

      Pages: 9619-9624

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17590909
  • [Journal Article] アルツハイマー病に対する非ウイルス性Aβ-DNAワクチン療法の開発2005

    • Author(s)
      大倉良夫, 宮越陽, 神山邦子, Matthias Staufenbiel, 松本陽
    • Journal Title

      Dementia Japan 13

      Pages: 36-36

    • Data Source
      KAKENHI-PROJECT-17590909
  • [Journal Article] Characterization of relapsing autoimmune encephalomyelitis and its treatment with decoy chemokine receptor gene2005

    • Author(s)
      Matsumoto, Y., Sakuma, H., Miyakoshi, A., Tsukada, Y., Kohyama, K., Park, I., Naoyuki, T.
    • Journal Title

      J.Neuroimmunol. 170

      Pages: 49-61

    • Data Source
      KAKENHI-PROJECT-17590909
  • [Patent] アルツハイマー病に対するDNAワクチン2010

    • Inventor(s)
      松本陽
    • Industrial Property Rights Holder
      財団法人東京都医学研究機構
    • Industrial Property Number
      2009-075823
    • Filing Date
      2010-03-26
    • Data Source
      KAKENHI-PROJECT-21591103
  • [Presentation] アルツハイマー病に対する非ウイルス性DNAワクチン療法の開発-新型ワクチンの開発2011

    • Author(s)
      松本陽
    • Organizer
      セミナー「アルツハイマー病に関する薬品開発動向」
    • Place of Presentation
      東京・大井町きゅりあん(招待講演)
    • Year and Date
      2011-04-28
    • Data Source
      KAKENHI-PROJECT-21591103
  • [Presentation] Aベータ亜種、及びアミロイド原性脳内蛋白に対応する非ウイルス性DNAワクチンの開発2010

    • Author(s)
      松本陽、神山邦子、加地健太郎
    • Organizer
      日本神経病理学会
    • Place of Presentation
      東京
    • Year and Date
      2010-04-24
    • Data Source
      KAKENHI-PROJECT-21591103
  • [Presentation] 老齢アカゲザルを用いたアルツハイマー病に対する非ウイルス性DNAワクチンの薬効と安全性試験2009

    • Author(s)
      松本陽、時田偉子、神山邦子、大倉良夫
    • Organizer
      第21回日本神経免疫学会学術集会
    • Place of Presentation
      大阪
    • Year and Date
      2009-03-15
    • Data Source
      KAKENHI-PROJECT-21591103
  • [Presentation] Non-viral Abeta DNA vaccine therapy against Alzheimer's disease2009

    • Author(s)
      Matsumoto, Y.
    • Organizer
      Second German-Japanese Neuroimmunology Symposium
    • Place of Presentation
      Zugspitze, Germany
    • Year and Date
      2009-07-20
    • Data Source
      KAKENHI-PROJECT-21591103
  • 1.  KOHYAMA Kuniko (80301795)
    # of Collaborated Projects: 8 results
    # of Collaborated Products: 15 results
  • 2.  TANUMA Naoyuki (00281676)
    # of Collaborated Projects: 6 results
    # of Collaborated Products: 0 results
  • 3.  KAWAZOE Yoko (60281705)
    # of Collaborated Projects: 5 results
    # of Collaborated Products: 0 results
  • 4.  MATSUBARA Shiro (00143884)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 0 results
  • 5.  KOJIMA Takashi (30225429)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 0 results
  • 6.  OKURA Yosio (10392367)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 9 results
  • 7.  ISHIHARA Yoshihiro (50079711)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 8.  NIIMI Naoko (90405043)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 9.  ABE Satoshi (90202663)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 10.  WATABE Kazuhiko (30240477)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 11.  OYANAGI Kiyomitsu (00134958)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 12.  安保 徹 (30005079)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 13.  渡部 久実 (50143756)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 14.  佐久間 啓
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 15.  尹 元基
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 16.  申 台均
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 17.  池 映欣
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 18.  JEE Youngheun
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results

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