IWASAKA Hideo 岩坂日出男

… Alternative Names

NISHIMARU Naoko

岩坂日出男イワサカヒデオ

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Researcher Number	90175216
Other IDs
Affiliation (based on the past Project Information) *help	2008 – 2012: 大分大学, 医学部, 准教授 2003 – 2006: Oita University, 医学部, Associate Professor 2002: Oita Medical University, Physiology, Associate Professor 2001 – 2002: 大分医科大学, 医学部, 助教授 1996 – 1998: 大分医科大学, 医学部, 講師 1993: 大分医科大学, 医学部, 助手
Review Section/Research Field	Principal Investigator Emergency medicine / Anesthesiology/Resuscitation studies Except Principal Investigator Anesthesiology/Resuscitation studies / Anesthesiology/Resuscitation studies
Keywords	Principal Investigator UCP-2 / アポトーシス / 手術侵襲 / mitochondria / apoptosis / ethyl pyruvate / Cerebeal ischemic reperfusion injury / HMGB1 / ミトコンドリア / エチルピルビン酸 … More / 脳虚血再灌流障害 / 炭水化物飲料 / 銅 / 亜鉛 / 重症患者 / 心臓手術 / 免疫 / 微量元素 / 栄養学 / 時計遺伝子 / 長寿遺伝子 / カロリー制限 / autophagy / 重症病態 / 帯状疱疹 / NMP / 敗血症 / 敗血症性ショック / コルチゾール / サイトカイン / Fas-Ligand / Bcl-2 / sFas / リンパ球 / 好中球 / 熱ショックプロテイン70 / インターロイキン6 / 肝切除術 … More Except Principal Investigator pulmonary fibrosis / collagen / HSP47 antisense / paraquat / アンチセンス / HSP / 線維化 / 肺線維化 / HSP47 / コラーゲン / 肺線維症 / Hsp47 / パラコート / Lactate / ^<31>P NMR / Ischemic preconditioning / 高炭酸アシドーシス / 乳酸 / 燐核磁気共鳴法 / 脳虚血耐性現象 / 敗血症 / 感染症 Less

重症病態の栄養学的介入による細胞エネルギー代謝調節因子の解明と新栄養療法の開発Principal Investigator
- Principal Investigator
  
  岩坂日出男
- Project Period (FY)
  2010 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Emergency medicine
- Research Institution
  Oita University
Development of new therapeutic strategies for severe sepsis by blood purification therapy targeting at elimination of HMGB1.
- Principal Investigator
  
  HIDAKA Seigo
- Project Period (FY)
  2008 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Anesthesiology/Resuscitation studies
- Research Institution
  Oita University
Molecular biologic approach for brain esucitation at the level of mitochondria in cerebral ischemic reperfusion injuryPrincipal Investigator
- Principal Investigator
  
  IWASAKA Hideo
- Project Period (FY)
  2004 – 2006
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Emergency medicine
- Research Institution
  Oita University
The effect of HSP47 antisense to protect the pulmonary fibrosis caused by paraquat intoxication
- Principal Investigator
  
  YAMAMOTO Hitoshi
- Project Period (FY)
  2002 – 2003
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Anesthesiology/Resuscitation studies
- Research Institution
  Oita University
  大分医科大学
Lactate utilization as an energy substrate in ischemic and thermal preconditoned rat brain slices
- Principal Investigator
  
  KITANO Takashi
- Project Period (FY)
  2001 – 2002
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Anesthesiology/Resuscitation studies
- Research Institution
  Oita Medical University
麻酔・手術侵襲の客観的指標としての細胞アポトーシス測定の有用性の検討Principal Investigator
- Principal Investigator
  
  岩坂日出男
- Project Period (FY)
  1996 – 1998
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Anesthesiology/Resuscitation studies
- Research Institution
  大分医科大学
麻酔および手術侵襲におけるストレス蛋白質の誘導およびその細胞防御機構の解明Principal Investigator
- Principal Investigator
  
  岩坂日出男
- Project Period (FY)
  1993
- Research Category
  
  Grant-in-Aid for Encouragement of Young Scientists (A)
- Research Field
  
  Anesthesiology/Resuscitation studies
- Research Institution
  大分医科大学

All 2012 2011 2010 2007 2006 2005 2004

All Journal Article Presentation

[Journal Article] Alternate day calorie restriction improves systemic inflammation in a mouse model of sepsis induced by cecal ligation and puncture2012
- Author(s)
  Hasegawa A, Iwasaka H, 他4名
- Journal Title
  
  J Surg Res
  
  Volume: 174 Pages: 136-141
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22592018
[Journal Article] Filtration leukocytapheresis therapy ameliorates LPS-induced systemic inflammation in a rat model.2010
- Author(s)
  Satoshi Hagiwara, Hideo Iwasaka, Akira Hasegawa, Seigo Hidaka, Aya Uno, Kaori Ueo, Tomohisa Uchida, Takayuki Noguchi.
- Journal Title
  
  J Surg Res. 8
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591836
[Journal Article] Continuous Hemodiafiltration Therapy Ameliorates LPS-Induced Systemic Inflammation in a Rat Model.2010
- Author(s)
  Satoshi Hagiwara, Hideo Iwasaka, Akira Hasegawa, Seigo Hidaka, Aya Uno, Ueo Kaori, Tomohisa Uchida, Takayuki Noguchi.
- Journal Title
  
  J Surg Res. 29
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591836
[Journal Article] Antisene oligonucleotide inhibition of heat shock protein(HSP)47 improves bleomycin-induced pulmonary fibrosis in rats2007
- Author(s)
  Satoshi Hagiwara, Hideo Iwasaka, Shigekiyo Matsumoto, Takayuki Noguchi
- Journal Title
  
  Respiratory Research 8
  
  Pages: 37-47
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-14571450
[Journal Article] An antisense oligonucleotide to HSP 47 inhibits paraquat-induced pulmonary fibrosis in rats2007
- Author(s)
  Satoshi Hagiwara, Hideo Iwasaka, Shigekiyo Matsumoto, Takayuki Noguchi
- Journal Title
  
  Toxicology 236
  
  Pages: 199-207
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-14571450
[Journal Article] Coexpression of HSP47 gene and type I and type III collagen genes in LPS-induced pulmonary fibrosis in rats2007
- Author(s)
  Satoshi Hagiwara, Hideo Iwasaka, Shigekiyo Matsumoto, Takayuki Noguchi, Hidekatsu Yoshioka
- Journal Title
  
  Lung 185
  
  Pages: 31-37
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14571450
[Journal Article] Coexpression of HSP47 gene and type I and type III collagengenes in LPS-induced pulmonary fibrosis in rats2007
- Author(s)
  Satoshi Hagiwara, Hideo Iwasaka, Shigekiyo Matsumoto, Takayuki Noguchi, Hidekatsu Yoshioka
- Journal Title
  
  Lung 185
  
  Pages: 31-37
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-14571450
[Journal Article] Introduction of antisense oligonucleotides to heat shock protein 47 prevents pulmonary fibrosis in lipopolysaccharide-induced pneumopathy of the rat2007
- Author(s)
  Satoshi Hagiwara, Hideo Iwasaka, Shigekiyo Matsumoto, Takayuki Noguchi
- Journal Title
  
  European Journal of Pharmacology 564
  
  Pages: 174-180
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-14571450
[Journal Article] 侵襲に対する生体防御法の開発2006
- Author(s)
  岩坂日出男、野口隆之
- Journal Title
  
  侵襲と免疫 15
  
  Pages: 41-45
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16591811
[Journal Article] ストレス蛋白研究の現状と展望2006
- Author(s)
  岩坂日出男
- Journal Title
  
  ICUとCCU 30
  
  Pages: 327-335
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16591811
[Journal Article] Stress protein : Currents and Perspectives.(In Japanese)2006
- Author(s)
  Hideo Iwasaka.
- Journal Title
  
  ICU and CCU 30
  
  Pages: 327-335
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16591811
[Journal Article] New therapeutic developments to stress.(In Japaese)2006
- Author(s)
  Hideo Iwasaka, Takayuki Noguchi
- Journal Title
  
  Surgical Trauma and Immunological Responses 15
  
  Pages: 41-45
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16591811
[Journal Article] Stress(Heat shock)response : to anesthesia and surgical stress.(In Japanese)2005
- Author(s)
  Hideo Iwasaka
- Journal Title
  
  Therapeutic Research 26
  
  Pages: 1617-1624
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16591811
[Journal Article] 麻酔・手術侵襲とストレス応答2005
- Author(s)
  岩坂日出男
- Journal Title
  
  Therapeutic Research 26
  
  Pages: 1617-1624
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16591811
[Journal Article] New mediator HMGB1 in sepsis and its therapeutic managements.(In Japanese)2004
- Author(s)
  Hideo Iwasaka
- Journal Title
  
  Surgery Frontier 11
  
  Pages: 119-124
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16591811
[Journal Article] 敗血症の新規メディエータHMGB1とその制御2004
- Author(s)
  岩坂日出男
- Journal Title
  
  Surgery Frontier 11
  
  Pages: 119-124
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16591811
[Presentation] The changes serum zinc and copper balance after cardiac surgery2011
- Author(s)
  Hideo Iwasaka
- Organizer
  第33回ヨーロッパ静脈経腸栄養学会
- Place of Presentation
  イエテボリ
- Year and Date
  2011-09-05
- Data Source
  KAKENHI-PROJECT-22592018
[Presentation] Effects of nutritional intervention on sepsis induced autophagy in mice septic model2011
- Author(s)
  Hideo Iwasaka
- Organizer
  第10回世界炎症学会
- Place of Presentation
  パリ
- Year and Date
  2011-06-27
- Data Source
  KAKENHI-PROJECT-22592018

1. KITANO Takashi (20211196)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
2. HIDAKA Seigo (00404385)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
3. YAMAMOTO Hitoshi (80295188)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
4. UNOSHIMA Masako (90336256)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
5. 伊東浩司 (30253793)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. 山田直子(西丸直子) (60101086)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results

IWASAKA Hideo 岩坂 日出男

NISHIMARU Naoko

岩坂 日出男 イワサカ ヒデオ

Research Projects

Research Products

Co-Researchers

重症病態の栄養学的介入による細胞エネルギー代謝調節因子の解明と新栄養療法の開発Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Development of new therapeutic strategies for severe sepsis by blood purification therapy targeting at elimination of HMGB1.

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Molecular biologic approach for brain esucitation at the level of mitochondria in cerebral ischemic reperfusion injuryPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

The effect of HSP47 antisense to protect the pulmonary fibrosis caused by paraquat intoxication

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Lactate utilization as an energy substrate in ischemic and thermal preconditoned rat brain slices

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

麻酔・手術侵襲の客観的指標としての細胞アポトーシス測定の有用性の検討Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

麻酔および手術侵襲におけるストレス蛋白質の誘導およびその細胞防御機構の解明Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Alternate day calorie restriction improves systemic inflammation in a mouse model of sepsis induced by cecal ligation and puncture2012

Author(s)

Journal Title

Data Source

[Journal Article] Filtration leukocytapheresis therapy ameliorates LPS-induced systemic inflammation in a rat model.2010

Author(s)

Journal Title

Data Source

[Journal Article] Continuous Hemodiafiltration Therapy Ameliorates LPS-Induced Systemic Inflammation in a Rat Model.2010

Author(s)

Journal Title

Data Source

[Journal Article] Antisene oligonucleotide inhibition of heat shock protein(HSP)47 improves bleomycin-induced pulmonary fibrosis in rats2007

Author(s)

Journal Title

Description

Data Source

[Journal Article] An antisense oligonucleotide to HSP 47 inhibits paraquat-induced pulmonary fibrosis in rats2007

Author(s)

Journal Title

Description

Data Source

[Journal Article] Coexpression of HSP47 gene and type I and type III collagen genes in LPS-induced pulmonary fibrosis in rats2007

Author(s)

Journal Title

Description

Data Source

[Journal Article] Coexpression of HSP47 gene and type I and type III collagengenes in LPS-induced pulmonary fibrosis in rats2007

Author(s)

Journal Title

Description

Data Source

IWASAKA Hideo 岩坂日出男

岩坂日出男イワサカヒデオ