YOSHINO Hiroaki 吉野裕顕

Researcher Number	90182807
External Links
Affiliation (based on the past Project Information) *help	2018: 秋田大学, 医学(系)研究科(研究院), 准教授 2011 – 2013: 秋田大学, 医学(系)研究科(研究院), 准教授 2007: 秋田大学, 医学部, 講師 1999 – 2006: 秋田大学, 医学部, 助手 1994 – 1997: 秋田大学, 医学部, 助手 1987 – 1991: 秋田大学, 医学部, 助手 1990: 秋田, 医学部, 助手
Review Section/Research Field	Principal Investigator Pediatric surgery / 小児外科 / Pediatric surgery Except Principal Investigator Pediatric surgery / 小児外科 / Digestive surgery / Obstetrics and gynecology / Pediatric surgery / General surgery / Basic Section 55010:General surgery and pediatric surgery-related
Keywords	Principal Investigator ECMO / 胎児治療 / 先天性横隔膜ヘルニア / 人工子宮 / 肺低形成 / Congenital diaphragmatic hernia / Lamb / ω3系脂肪酸 / 肝臓星細胞 / ビタミンA … More Except Principal Investigator マイクロダイアリシス / 広範小腸切除 / アルギニン / 吸収能 / microdialysis / 胆道閉鎖症 / 微細形態 / 胆汁 / ヤツメウナギ / 肺低形成 / oligohydramnios / pulmonary hypoplasia / ECMO / 腎線維化 / 消化管運動 / テレメーターシステム / massive small intestinal resection / Arginine / nitric oxide / 肝移植 / 近赤外分光法 / ヤツメナギ / 胆汁酸 / コレステロール / ビタミンA / 星細胞 / 毛細胆管 / 肝臓 / 高速液クロ / コラーゲン / 線維化 / アポトーシス / 肝臓星細胞 / 細胞外マトリックス / レチノイド / TUNEL法 / 羊水過少症 / 横隔膜ヘルニア / 肺サ-ファクタント / Fetus / Pulmonary hypoplasia / Pulmonary surfactant / Oligohydramnios / congenital diaphyragmatic hernia / diaphragmatic hernia / pulmonary surfactant / 先天性横隔膜ヘルニア / 胎児手術 / 人工子宮 / 羊胎仔 / 胎児治療 / 子宮内胎児治療 / 子宮外胎児治療 / Fetal surgery / Congenital diaphragmatic hernia / Hypoplastic lung / Artificial placenta. / Lamb / 成長因子 / 成長ホルモン / 腸管粘膜増殖 / 腸管の成長 / massive small bowel resection / arginine / growth factor / growth hormone / intestinal growth / tubulointerstitial fibrosis / 短小腸 / 一酸化窒素(NO) / アルギニン欠乏 / シトルリン / focal tubulointerstitial fibrosis / short small bowel / renal tubulointerstitial fibrosis / nitric oxide (NO) / arginine deficiency / citrulline / テレメータシステム / intestinal motility / Telemeter system / absorption function / 胃腸運動 / 消化吸収 / gastrointestinal motility / telemeter system / 手術侵襲 / 精神発達 / 侵襲ホルモン / 発達指数 / BendenーGestalt Test / WISCーR Test / 新生児 / 乳児 / 身体発育 / 小児 / 生体反応 / 視床下部 / 下垂体系ホルモン / 交感神経 / 副腎髄質系 / 下垂体 / 副腎皮質系 / 精神身体発達 / Surgical stress / Mental development / Stress hormones / Development quotient / Bender-Gestalt test / WISC-R test / ω３系脂肪酸 / 脂肪肝 / 短腸症候群 / 腸管不全合併肝障害 Less

ω3系脂肪酸の肝庇護作用と脂質プロファイル網羅的解析による肝障害の新規治療戦略Ongoing
- Principal Investigator
  
  森井真也子
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 55010:General surgery and pediatric surgery-related
- Research Institution
  Akita University
The effect of omega-3 fatty acids on hepatic stellate cell activationPrincipal Investigator
- Principal Investigator
  
  YOSHINO Hiroaki
- Project Period (FY)
  2011 – 2013
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Pediatric surgery
- Research Institution
  Akita University
胆道閉鎖症治療への応用を目指した胆汁成分の新しい処理機構の解明
- Principal Investigator
  
  妹尾春樹
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Pediatric surgery
- Research Institution
  Akita University
Arginine effect on the gastrointestinal motility in the growing rat after massive small bowel resection
- Principal Investigator
  
  HEBIGUCHI Tatsuzo
- Project Period (FY)
  2005 – 2006
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Pediatric surgery
- Research Institution
  Akita University
胆汁成分の新規処理機構の解明-胆道閉鎖症治療への応用を目指して-
- Principal Investigator
  
  妹尾春樹
- Project Period (FY)
  2003 – 2005
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Pediatric surgery
- Research Institution
  Akita University
Arginine effect on the absorption and motor functions of the residual ileum after massive small intestinal resection
- Principal Investigator
  
  HEBIGUCHI Tatsuzo
- Project Period (FY)
  2003 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Pediatric surgery
- Research Institution
  Akita University
A STUDY OF ARGININE ACTION ON RENAL TUBULOINTERSTITIAL FIBROSIS AFTER MASSIVE SMALL BOWEL RESECTION IN GROWING RATS
- Principal Investigator
  
  HEBIGUCHI Tatsuzo
- Project Period (FY)
  2000 – 2001
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Pediatric surgery
- Research Institution
  Akita University
Experimental Study of Extrauterine Fetal Teatment for Congenital Diaphragmatic HerniaPrincipal Investigator
- Principal Investigator
  
  YOSHINO Hiroaki
- Project Period (FY)
  1999 – 2002
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Pediatric surgery
- Research Institution
  Akita University
Nitric oxide産生抑制による生体部分肝移植後肝不全の予防
- Principal Investigator
  
  浅沼義博
- Project Period (FY)
  1996 – 1997
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Digestive surgery
- Research Institution
  Akita University
The effect of arginine supplementation on intestinal growth and absorption after massive small bowel resection in growing rats
- Principal Investigator
  
  HEBIGUCHI Tatsuzo
- Project Period (FY)
  1996 – 1997
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  小児外科
- Research Institution
  Akita University
Experimental Study for Extrauterine Incubation and Breathing of Fetal LambsPrincipal Investigator
- Principal Investigator
  
  YOSHINO Hiroaki
- Project Period (FY)
  1996 – 1997
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  小児外科
- Research Institution
  Akita University
Extrauterine Fetal Treatment for Congenital Diaphragmatic Hernia
- Principal Investigator
  
  KATO Tetsuo
- Project Period (FY)
  1994 – 1996
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  小児外科
- Research Institution
  Akita University School of Medicine
Pulmonary Hypoplasia and Morphological Characteristics and Surfactant Content Following Oligohydramnios or Diaphragmatic Hernia.
- Principal Investigator
  
  HIGUCHI Motokazu
- Project Period (FY)
  1989 – 1991
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Obstetrics and gynecology
- Research Institution
  Akita University
Effects of Surgical Stress in Children on Mental and Physical Development
- Principal Investigator
  
  KATO Tesuo
- Project Period (FY)
  1987 – 1989
- Research Category
  
  Grant-in-Aid for General Scientific Research (B)
- Research Field
  
  General surgery
- Research Institution
  Akita University

All 2014 2013 2012 2011

All Journal Article Presentation Book

[Book] Cholestasis-How do lampreys avoid cholestasis after bile duct degeneration-(ed. Tripodi V.)2011
- Author(s)
  Morii M., Mezaki Y., Yoshikawa K., Miura M., Imai K., Hebuguchi T., Watanabe R., Asanuma Y., Yoshino H., Senoo H
- Publisher
  INTECH
- Data Source
  KAKENHI-PROJECT-23592623
[Journal Article] The role of retinoic acid receptors in activated hepatic stellate cells.2013
- Author(s)
  Mezaki Y., Morii M., Hebiguchi T., Yoshikawa K., Yamaguchi N, Yoshino H., Senoo H
- Journal Title
  
  Medical Hypotheses
  
  Volume: 81(2) Pages: 222-224
- DOI
  10.1016/j.mehy.2013.04.045
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23592623, KAKENHI-PROJECT-24614003, KAKENHI-PROJECT-25504001
[Journal Article] エタノールロック療法におけるカテーテル内エタノール濃度の検討2013
- Author(s)
  森井真也子,目崎喜弘,蛇口琢,渡部亮,妹尾春樹,吉野裕顕
- Journal Title
  
  日本小児栄養消化器肝臓学会雑誌
  
  Volume: 27(2) Pages: 133-137
- URL
  http://mol.medicalonline.jp/library/archive/search?jo=dl7pedga&vo=27&nu=2&st=133
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23592623
[Journal Article] Differential Increases in the Expression of Intermediate Filament Proteins and Concomitant Morphological Changes of Transdifferentiating Rat Hepatic Stellate Cells Observed <i>In Vitro</i>2013
- Author(s)
  Mezaki Y., Morii M., Hebiguchi T., Yoshikawa K., Yamaguchi N, Miura M., Imai K., Yoshino H., Senoo H
- Journal Title
  
  ACTA HISTOCHEMICA ET CYTOCHEMICA
  
  Volume: 46(4) Issue: 5 Pages: 137-143
- DOI
  10.1267/ahc.13007
- NAID
  130003381866
- ISSN
  0044-5991, 1347-5800
- Language
  English
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23592623, KAKENHI-PROJECT-24614003, KAKENHI-PROJECT-25504001
[Journal Article] 小児における腸管不全合併肝障害に対するω3系脂肪製剤投与の検討2012
- Author(s)
  森井真也子,吉野裕顕,蛇口琢,渡部亮,目崎喜弘,南條博,妹尾春樹,和田基,仁尾正記,蛇口達造
- Journal Title
  
  外科と代謝・栄養
  
  Volume: 46(6) Pages: 159-167
- URL
  http://mol.medicalonline.jp/library/archive/search?jo=dj5surgi&vo=46&nu=6&st=159
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23592623
[Journal Article] 小児における腸管不全合併肝障害に対するω3系脂肪製剤投与の検討2012
- Author(s)
  森井真也子、吉野裕顕、蛇口琢、渡部亮、目崎喜弘、南條博、妹尾春樹、和田基、　仁尾正記、蛇口達造
- Journal Title
  
  外科と代謝・栄養
  
  Volume: 46 Pages: 159-167
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23592623
[Journal Article] Characterization of a cellular retinol-binding protein from lamprey, Lethenteron japonicum.2012
- Author(s)
  Mezaki Y., Morii M., Yoshikawa K., Yamaguchi N., Miura M., Imai K., Yoshino H., Senoo H
- Journal Title
  
  Comp Biochem Physiol B Biochem Mol Biol
  
  Volume: 161(3) Pages: 233-239
- DOI
  10.1016/j.cbpb.2011.11.011
- NAID
  10031086293
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23592623, KAKENHI-PROJECT-23790269, KAKENHI-PROJECT-23792026
[Journal Article] 腸管不全合併肝障害に対してω-3系脂肪製剤を投与した2症例の検討2011
- Author(s)
  森井真也子, 吉野裕顕, 蛇口琢, 南條博, 野口篤子, 高橋勉, 目崎喜弘, 妹尾春樹, 蛇口達造
- Journal Title
  
  小児外科
  
  Volume: 43 Pages: 380-387
- URL
  http://www.tokyo-igakusha.co.jp/f/b/index/zc01/5/oa_table/b_z_top.html
- Data Source
  KAKENHI-PROJECT-23592623
[Presentation] 短小腸下でのビタミンA吸収・貯蔵メカニズムの解明2014
- Author(s)
  蛇口琢,目崎喜弘,森井真也子,渡部亮,吉川究,今井克幸,三浦光隆,吉野裕顕,妹尾春樹
- Organizer
  第119回日本解剖学会総会・全国学術集会
- Place of Presentation
  下野, 栃木
- Year and Date
  2014-03-27
- Data Source
  KAKENHI-PROJECT-23592623
[Presentation] 短小腸下におけるビタミンA 吸収・貯蔵機構の解明～短小腸ラットモデルを用いた検討～2014
- Author(s)
  蛇口琢、森井真也子、渡部亮、目崎喜弘、妹尾春樹、吉野裕顕
- Organizer
  第51回日本小児外科学会
- Place of Presentation
  大阪
- Data Source
  KAKENHI-PROJECT-23592623
[Presentation] 短小腸下におけるビタミンA吸収・貯蔵機構の解明～短小腸ラットモデルを用いた検討～2014
- Author(s)
  蛇口琢,森井真也子,渡部亮,目崎喜弘,妹尾春樹,吉野裕顕
- Organizer
  第51回日本小児外科学会学術集会
- Place of Presentation
  大阪
- Year and Date
  2014-05-09
- Data Source
  KAKENHI-PROJECT-23592623
[Presentation] 短小腸下でのビタミンA吸収・貯蔵メカニズムの解明2014
- Author(s)
  蛇口琢、目崎喜弘、森井真也子、渡部亮、吉川究、今井克幸、吉野裕顕、妹尾春樹
- Organizer
  第119回日本解剖学会総会・全国学術集会
- Place of Presentation
  栃木
- Data Source
  KAKENHI-PROJECT-23592623
[Presentation] 腸管不全合併肝障害ラットモデルの作製2013
- Author(s)
  Hebiguchi T., Morii M., Watanabe R., Mezaki Y., Senoo H., Yoshino H., Imai K., Miura M., Yoshikawa K., Yamaguchi N
- Organizer
  第118回日本解剖学会総会・全国学術集会
- Place of Presentation
  高松, 香川
- Year and Date
  2013-03-28
- Data Source
  KAKENHI-PROJECT-23592623
[Presentation] ヤツメウナギにおける胆汁排泄機構2013
- Author(s)
  森井真也子,目崎喜弘,吉川究,山口典子,三浦光隆,今井克幸,蛇口琢,渡部亮,妹尾春樹,吉野裕顕
- Organizer
  第118回日本解剖学会総会・全国学術集会
- Place of Presentation
  高松, 香川
- Year and Date
  2013-03-30
- Data Source
  KAKENHI-PROJECT-23592623
[Presentation] 腸管不全合併肝障害ラットモデルの作製2013
- Author(s)
  蛇口琢,　森井真也子, 渡部亮, 吉野裕顕, 目崎喜弘, 山口典子, 吉川究, 今井克幸, 三浦光隆, 妹尾春樹
- Organizer
  第118回解剖学会総会・全国学術集会
- Place of Presentation
  高松
- Data Source
  KAKENHI-PROJECT-23592623
[Presentation] 胆道閉鎖症患児に対するω-3系脂肪製剤投与の経験2012
- Author(s)
  森井真也子,蛇口琢,渡部亮,吉野裕顕,目崎喜弘,山口典子,吉川究,今井克幸,三浦光隆,妹尾春樹
- Organizer
  第49回日本小児外科学会学術集会
- Place of Presentation
  横浜,神奈川
- Year and Date
  2012-05-16
- Data Source
  KAKENHI-PROJECT-23592623
[Presentation] 胆道閉鎖症患児に対するω-3系脂肪製剤投与の経験2012
- Author(s)
  森井真也子, 蛇口琢, 渡部亮, 吉野裕顕, 目崎喜弘, 山口典子, 吉川究, 今井克幸, 三浦光隆, 妹尾春樹
- Organizer
  第49回日本小児外科学会学術集会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-23592623
[Presentation] 在宅中心静脈カテーテル管理におけるエタノールロック療法の検討2012
- Author(s)
  森井真也子,平野尚子,蛇口琢,渡部亮,目崎喜弘,妹尾春樹,三浦昌朋,吉野裕顕
- Organizer
  第39回日本小児栄養消化器肝臓学会
- Place of Presentation
  大阪, 大阪
- Year and Date
  2012-07-15
- Data Source
  KAKENHI-PROJECT-23592623
[Presentation] 腸管不全合併肝障害に対してω3系脂肪製剤を長期投与した1例2012
- Author(s)
  森井真也子,蛇口琢,渡辺亮,目崎喜弘,妹尾春樹,和田基,仁尾正記,吉野裕顕
- Organizer
  第28回日本小児外科学会秋季シンポジウム/第42回日本小児外科代謝研究会/Pediatric Surgery Joint Meeting 2012
- Place of Presentation
  静岡, 静岡
- Year and Date
  2012-11-02
- Data Source
  KAKENHI-PROJECT-23592623
[Presentation] The metabolism of cholesterol after bile duct degeneration in lamprey2012
- Author(s)
  Morii M., Mezaki Y., Yamaguchi N., Yoshikawa K., Imai K., Miura M., Yoshino H., Hebiguchi T., Asanuma Y., Hebiguchi T., Senoo H
- Organizer
  第117回日本解剖学会総会・全国学術集会
- Place of Presentation
  甲府,山梨
- Year and Date
  2012-03-27
- Data Source
  KAKENHI-PROJECT-23592623
[Presentation] ω3系脂肪製剤を使用した,短腸症候群2例の経験2011
- Author(s)
  森井真也子, 吉野裕顕, 蛇口琢, 目崎喜弘, 山口典子, 吉川究, 三浦光隆, 今井克幸, 妹尾春樹, 蛇口達造
- Organizer
  第48回日本小児外科学会学術集会
- Place of Presentation
  東京
- Year and Date
  2011-07-22
- Data Source
  KAKENHI-PROJECT-23592623
[Presentation] 腸管不全合併肝障害にω3系脂肪製剤が著効した短腸症候群の2例2011
- Author(s)
  森井真也子,吉野裕顕,和田基,蛇口琢,目崎喜弘,山口典子,吉川究,三浦光隆,今井克幸,妹尾春樹,仁尾正記,蛇口達造
- Organizer
  日本外科代謝栄養学会第48回学術集会
- Place of Presentation
  名古屋,愛知
- Year and Date
  2011-07-08
- Data Source
  KAKENHI-PROJECT-23592623
[Presentation] Reversibility of periductal fibrosis during biliary atresia in the lamprey2011
- Author(s)
  Morii M., Yoshino H., Hebiguchi T., Mezaki Y., Yamaguchi N., Yoshikawa K., Miura M., Imai K., Senoo H., Hebiguchi T
- Organizer
  16th International Symposium on Cells of Hepatic Sinusoid
- Place of Presentation
  Florence, Italy
- Year and Date
  2011-09-23
- Data Source
  KAKENHI-PROJECT-23592623

1. KATO Tetsuo (20004963)

# of Collaborated Projects: 11 results

# of Collaborated Products: 0 results
2. HEBIGUCHI Tatsuzou (00124644)

# of Collaborated Projects: 7 results

# of Collaborated Products: 0 results
3. SAGESHIMA Naoto (10153967)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
4. 芳川究 (90400481)

# of Collaborated Projects: 2 results

# of Collaborated Products: 2 results
5. MORII Mayako (10375280)

# of Collaborated Projects: 2 results

# of Collaborated Products: 23 results
6. HEBIGUCHI Taku (20375281)

# of Collaborated Projects: 2 results

# of Collaborated Products: 21 results
7. HIGUCHI Motokazu (20006779)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
8. 妹尾春樹 (90171355)

# of Collaborated Projects: 2 results

# of Collaborated Products: 2 results
9. 萱場広之 (70224706)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
10. SAITO Masahiro (70162229)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. HIRANO Hideto (80156687)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. TAMURA Masamiti (10270844)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
13. HARADA Kenji (20221509)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
14. 浅沼義博 (20142937)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
15. 佐藤勤 (90235367)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
16. 入江俊明 (90231167)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
17. 伊藤正毅 (40126389)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
18. 佐藤充 (60226008)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
19. 東伸好 (60361218)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
20. 佐藤岳哉 (10312696)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
21. 山口典子 (90251553)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
22. 目崎喜弘 (40431621)

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
23. 渡部亮 (80638255)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results

YOSHINO Hiroaki 吉野 裕顕

Research Projects

Research Products

Co-Researchers

ω3系脂肪酸の肝庇護作用と脂質プロファイル網羅的解析による肝障害の新規治療戦略Ongoing

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

The effect of omega-3 fatty acids on hepatic stellate cell activationPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Experimental Study of Extrauterine Fetal Teatment for Congenital Diaphragmatic HerniaPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Experimental Study for Extrauterine Incubation and Breathing of Fetal LambsPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Book] Cholestasis-How do lampreys avoid cholestasis after bile duct degeneration-(ed. Tripodi V.)2011

Author(s)

YOSHINO Hiroaki 吉野裕顕