OHTSUKI Mamitaro 大槻マミ太郎

… Alternative Names

大槻マミ太郎オオツキマミタロウ

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Researcher Number	90185330
External Links
Affiliation (Current)	2025: 自治医科大学, 医学部, 教授
Affiliation (based on the past Project Information) *help	2013: 自治医科大学, 医学部, 教授 2005 – 2007: 自治医科大学, 医学部, 教授 2002 – 2003: 自治医科大学, 医学部, 助教授 1994 – 1995: 東京大学, 医学部(病), 講師
Review Section/Research Field	Principal Investigator Dermatology Except Principal Investigator Dermatology
Keywords	Principal Investigator 尋常性乾癬 / HLAタイピング / HLA-C / STAT / 転写因子 / シグナル伝達 / IFN-γ / ケラチン / adhesion molecule / eosinoprie / patch test / mite allergen / atopic dermatitis … More Except Principal Investigator … More メラノーマ / Interferon-lambda / Adontive immune cell transfer / Histone deacetylase inhibitor / vaccine / Tumor immunology / Melanoma / interferon-λ / ヒストン脱アセチル化阻害剤 / インターフェロン-λ / 養子リンパ球移入 / ヒストン脱アセチル阻害剤 / ワクチン / 腫瘍免疫 / 薬剤反応性 / エピジェネティック修飾 / 生体内イメージング / 治療感受性 / 発現制御 / シグナル伝達 / がん Less

Understanding between the histone-chromatin modification and the possible augmentation of therapeutic sensitivity for malignant melanoma
- Principal Investigator
  
  MURAKAMI Takashi
- Project Period (FY)
  2011 – 2013
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Dermatology
- Research Institution
  Takasaki University of Health and Welfare
The study for inhibition of the melanoma-derived factors and for efficient elicitation of the host immunity
- Principal Investigator
  
  MURAKAMI Takashi
- Project Period (FY)
  2005 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Dermatology
- Research Institution
  Jichi Medical University
乾癬患者におけるナイーブCD4陽性T細胞特異的Krupple型転写因子群の機能Principal Investigator
- Principal Investigator
  
  大槻マミ太郎
- Project Period (FY)
  2002 – 2003
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Dermatology
- Research Institution
  Jichi Medical University
ケラチン遺伝子発現制御に関与する転写因子の精製・クローニングPrincipal Investigator
- Principal Investigator
  
  大槻マミ太郎
- Project Period (FY)
  1995
- Research Category
  
  Grant-in-Aid for Encouragement of Young Scientists (A)
- Research Field
  
  Dermatology
- Research Institution
  The University of Tokyo
ケラチン遺伝子調節領域DNAに結合する転写因子に関する研究Principal Investigator
- Principal Investigator
  
  大槻マミ太郎
- Project Period (FY)
  1994
- Research Category
  
  Grant-in-Aid for Encouragement of Young Scientists (A)
- Research Field
  
  Dermatology
- Research Institution
  The University of Tokyo

All 2007 2006 2005

All Journal Article Presentation

[Journal Article] Histone deacetylase inhibitior depsipeptide(FK228) suppresses the Ras-MAP kinase signaling pathway by up-regulation Rapt and induces apoptosis in malignant melanoma2006
- Author(s)
  Kobayashi Y, Ohtsuki M, Murakami T, Kobayashi T, Sutheesophon K, Kitayama H, Kano Y, Kusano E, NakaQawa H, Furukawa Y.
- Journal Title
  
  Oncogene 25(4)
  
  Pages: 512-524
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17591181
[Journal Article] Antitumor activity of interferon(IFN)-lambda in murine tumor models2006
- Author(s)
  Sato A, Ohtsuki M, Hata M, Kobayashi E, Murakami T.
- Journal Title
  
  Journal of Immunology 176(12)
  
  Pages: 7686-7694
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17591181
[Journal Article] Histone deacetylase inhibitor depsipeptide (FK228) suppresses the Ras-MAP kinase signaling pathway by up-regulation Rap1 and induces apoptosis in malignant melanoma2006
- Author(s)
  Kobayashi Y, Ohtsuki M, Murakami T, et al.
- Journal Title
  
  Oncogene 25(4)
  
  Pages: 512-524
- Data Source
  KAKENHI-PROJECT-17591181
[Journal Article] Antitumor activity of interferon(IFN)-lambda in murine tumor models2006
- Author(s)
  Sato A, Ohtsuki M, Hata M, Kobayashi E, Murakami, T
- Journal Title
  
  J Immunol 176(12)
  
  Pages: 7686-7694
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17591181
[Journal Article] Histone deacetylase inhibitor depsipeptide(FK228) suppresses the Ras-MAP kinase signaling pathway by up-regulation Rap1 and induces anontosis in malienant melanoma2006
- Author(s)
  Kobayashi Y, Ohtsuki M, Murakami T, et. al.
- Journal Title
  
  Oncogene 25
  
  Pages: 512-524
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17591181
[Journal Article] Antitumor activity of interferon (IFN)-lambda in murine tumor models2006
- Author(s)
  Sato A, Ohtsuki M, Hata M, Kobayashi E, Murakami T.
- Journal Title
  
  Journal of Immunology 176(12)
  
  Pages: 7686-9764
- Data Source
  KAKENHI-PROJECT-17591181
[Presentation] Differential antitumor activity between IFN-lambda and IL-212007
- Author(s)
  A Sato, M Ohtsuki, E Kobayashi, T Murakami
- Organizer
  The 94th Annual meeting of the American Society of Immunologists
- Place of Presentation
  Miami Beach,FL
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17591181
[Presentation] The antitumor activity of interferon-λ against murine tumors2006
- Author(s)
  A Sato, M Ohtsuki, E Kobayashi, T Murakami
- Organizer
  The 67th Society for Investigative Dermatology
- Place of Presentation
  Philadelphia,PA
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17591181
[Presentation] The antitumor activity of interferon-1 against murine tumors2006
- Author(s)
  A, Sato M, Ohtsuki E, Kobayashi T, Murakami
- Organizer
  The 67th Society for Investigative Dermatology
- Place of Presentation
  Philadelphia. PA
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17591181
[Presentation] ヒストン脱アセチル化阻害剤FK228はRap1/Krev-1を介して悪性黒色腫にアポトーシスを誘導する2005
- Author(s)
  小林由起子、大槻マミ太郎、村上孝、小林高久, ほか
- Organizer
  第64回日本癌学会学術総会
- Place of Presentation
  札幌
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17591181

1. MURAKAMI Takashi (00326852)

# of Collaborated Projects: 3 results

# of Collaborated Products: 10 results
2. SATO Atsuko (50382916)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
3. SAITO Katsuyo (90455288)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
4. KOBAYASHI Eiji (00245044)

# of Collaborated Projects: 1 results

# of Collaborated Products: 10 results
5. 藤本美津夫 (80326850)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results

OHTSUKI Mamitaro 大槻 マミ太郎

大槻 マミ太郎 オオツキ マミタロウ

Research Projects

Research Products

Co-Researchers

Understanding between the histone-chromatin modification and the possible augmentation of therapeutic sensitivity for malignant melanoma

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

The study for inhibition of the melanoma-derived factors and for efficient elicitation of the host immunity

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

乾癬患者におけるナイーブCD4陽性T細胞特異的Krupple型転写因子群の機能Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

ケラチン遺伝子発現制御に関与する転写因子の精製・クローニングPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

ケラチン遺伝子調節領域DNAに結合する転写因子に関する研究Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Histone deacetylase inhibitior depsipeptide(FK228) suppresses the Ras-MAP kinase signaling pathway by up-regulation Rapt and induces apoptosis in malignant melanoma2006

Author(s)

Journal Title

Description

Data Source

[Journal Article] Antitumor activity of interferon(IFN)-lambda in murine tumor models2006

Author(s)

Journal Title

Description

Data Source

[Journal Article] Histone deacetylase inhibitor depsipeptide (FK228) suppresses the Ras-MAP kinase signaling pathway by up-regulation Rap1 and induces apoptosis in malignant melanoma2006

Author(s)

Journal Title

Data Source

[Journal Article] Antitumor activity of interferon(IFN)-lambda in murine tumor models2006

Author(s)

Journal Title

Description

Data Source

[Journal Article] Histone deacetylase inhibitor depsipeptide(FK228) suppresses the Ras-MAP kinase signaling pathway by up-regulation Rap1 and induces anontosis in malienant melanoma2006

Author(s)

Journal Title

Description

Data Source

[Journal Article] Antitumor activity of interferon (IFN)-lambda in murine tumor models2006

Author(s)

Journal Title

Data Source

[Presentation] Differential antitumor activity between IFN-lambda and IL-212007

Author(s)

Organizer

Place of Presentation

Description

Data Source

[Presentation] The antitumor activity of interferon-λ against murine tumors2006

Author(s)

Organizer

Place of Presentation

Description

Data Source

[Presentation] The antitumor activity of interferon-1 against murine tumors2006

Author(s)

Organizer

Place of Presentation

Description

OHTSUKI Mamitaro 大槻マミ太郎

大槻マミ太郎オオツキマミタロウ