Kawarabayashi Takeshi 瓦林毅

… Alternative Names

Takeshi Kawarabayashi 瓦林毅

KAWARABAYASHI Takeshi 瓦林毅

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Researcher Number	90186156
Affiliation (Current)	2025: 群馬大学, 医学部, 非常勤講師
Affiliation (based on the past Project Information) *help	2019 – 2023: 群馬大学, 医学部, 非常勤講師 2017: 弘前大学, 大学院医学研究科, 准教授 2016 – 2017: 弘前大学, 医学研究科, 准教授 2014 – 2015: 弘前大学, 医学(系)研究科(研究院), 准教授 2006 – 2013: Hirosaki University, University Hospital, Assistant Professor, 医学部附属病院, 講師 … More 2011: 弘前大学, 医学部・附属病院, 講師 2009: 弘前大学, 附属病院, 講師 2008: Hirosaki University, 医学部・附属病院, 講師 2005: 岡山大学, 医学部・歯学部附属病院, 助手 Less
Review Section/Research Field	Principal Investigator Neurology / Basic Section 52020:Neurology-related Except Principal Investigator Neurology
Keywords	Principal Investigator アルツハイマー病 / タウ / アミロイド / Abeta / fyn / NMDA receptor / tau / lipid rafts / シヌクレイン / オリゴマー … More / リピドラフト / Alzheimer's disease / prion / oligomer / Alzheimer / synapse / NMDA受容体 / トランスジェニックマウス / コレステロール / アミロイドβ蛋白 / 神経分子病態学 / Alzheimer病 / transgenic mouse / exosome / apolipoprotein E / neurofilament / phosphryleted tau / 組み換え植物 / 組み替え植物 / 面期療法 / バイオマーカー / ダイズ / 免疫療法 / アミロイドbeta蛋白 / 疾患修飾療法 / 認知症 / 組み替え蛋白 / ワクチン / sinaptosome / 神経毒性 / vaccine / Abeta oligomer / 信号伝達 / レビー小体型認知症 / プリオン / synaptosome / Aβ / シナプス / ｆｙｎ / amyloid / 信号伝達系 / アミロイドss蛋白 / CHO cell / GPIアンカー … More Except Principal Investigator アルツハイマー病 / ELISA / SODG93A transgenic mice / FNK / IGF-1 / Alzheimer's disease / tau / Aβ / 家族性アルツハイマー病 / アミロイド / 病態修飾薬 / Western blot / 病理 / 認知機能 / Abeta / 脳アミロイド / Alzheimer病 / 認知症 / marker / Aβ oligomers / 診断マーカー / Aβオリゴマー / intrathecal infusion / neurotrophic factors / neural precursor cell / ant-apoptotic therapy / ALS / 筋萎縮性側索硬化症(ALS) / 抗アポトーシス治療法 / 髄腔内投与 / 神経栄養因子 / 再生治療 / 抗アポトーシス治療 / 筋萎縮性側索硬化症 / Therapy / Transgenic mouse / Neuronal cell death / As / 治療法 / トランスジェニックマウス / 神経細胞死 / バイオマーカー / 臨床神経学 / 神経科学 / 神経内科学 / 神経分子病態学 / 臨床応用 / 治療 / 診断 / オリゴマー / 神経病態生化学 Less

Analysis of Alzheimer's disease targeting lipid rafts and exosomePrincipal Investigator
- Principal Investigator
  
  瓦林毅
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 52020:Neurology-related
- Research Institution
  Gunma University
Development of prevention of Alzheimer's disease using transgenic soybean expressing amyloid beta proteinPrincipal Investigator
- Principal Investigator
  
  Takeshi Kawarabayashi
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 52020:Neurology-related
- Research Institution
  Gunma University
Identification of neurotoxic Abeta oligomers and development of therapy against themPrincipal Investigator
- Principal Investigator
  
  Kawarabayashi Takeshi
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Neurology
- Research Institution
  Hirosaki University
Development and clinical application of disease modifying drug for Alzheimer's Disease
- Principal Investigator
  
  Shoji Mikio
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Neurology
- Research Institution
  Hirosaki University
Analysis of pathogenesis of neurodegenerative diseases targeting synapsePrincipal Investigator
- Principal Investigator
  
  TAKESHI Kawarabayashi
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Neurology
- Research Institution
  Hirosaki University
Study for novel biomarkers for Alzheimer's disease
- Principal Investigator
  
  SHOJI Mikio
- Project Period (FY)
  2011 – 2012
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Neurology
- Research Institution
  Hirosaki University
Development of therapies targeting pathogenic oligomers in lipid raftsPrincipal Investigator
- Principal Investigator
  
  KAWARABAYASHI Takeshi
- Project Period (FY)
  2009 – 2011
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Neurology
- Research Institution
  Hirosaki University
Development and clinical application of novel methods for diagnosis and therapy of Alzheimer disease by regulation of neurotoxic oligomer
- Principal Investigator
  
  SHOJI Mikio
- Project Period (FY)
  2007 – 2009
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Neurology
- Research Institution
  Hirosaki University
Development of therapy targeting amyloid β protein oligomer in lipid raftsPrincipal Investigator
- Principal Investigator
  
  KAWARABAYASHI Takeshi
- Project Period (FY)
  2007 – 2008
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Neurology
- Research Institution
  Hirosaki University
The predictive or monitoring marker for Alzheimer's disease
- Principal Investigator
  
  MATSUBARA Etsuo
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Neurology
- Research Institution
  National Institute for Longevity Sciences,NCGG
Anti-apoptotic Therapy (Intrathecal Injection of Anti-apoptotic PTD-FNK Protein) in a Mouse Model of Amyotrophic Lateral Sclerosis
- Principal Investigator
  
  TAKEHISA Yasushi
- Project Period (FY)
  2005 – 2006
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Neurology
- Research Institution
  Okayama University
Development of therapy for deposits of AB and tau in Alzheimer disease.
- Principal Investigator
  
  SHOJI Mikio
- Project Period (FY)
  2004 – 2006
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Neurology
- Research Institution
  Hirosaki University
  Okayama University

[Book] 神経内科外来シリーズ／もの忘れ外来2016
- Author(s)
  瓦林毅，東海林幹夫
- Total Pages
  257
- Publisher
  メジカルビュー社
- Data Source
  KAKENHI-PROJECT-15K09305
[Book] アルツハイマー病の診断マーカー2011
- Author(s)
  瓦林毅,東海林幹夫
- Publisher
  よくわかって役に立つ認知症のすべて改訂第3版平井俊策編永井書店
- Data Source
  KAKENHI-PROJECT-21591069
[Book] 認知症学(上)-その解明と治療の最新知見-2011
- Author(s)
  瓦林毅
- Total Pages
  6
- Publisher
  日本臨床社
- Data Source
  KAKENHI-PROJECT-21591069
[Book] 日本臨床増刊号認知症学(上)-その解明と治療の最新知見2011
- Author(s)
  瓦林毅
- Publisher
  認知症研究に用いられる動物・細胞実験モデル遺伝子改変モデルAPP/PS-1
- Data Source
  KAKENHI-PROJECT-21591069
[Book] よくわかって役に立つ認知症のすべて改訂第3版2011
- Author(s)
  瓦林毅, 東海林幹夫
- Total Pages
  14
- Publisher
  永井書店
- Data Source
  KAKENHI-PROJECT-21591069
[Book] アルツハイマー病モデル.疾患モデルマウス・ラット活用ハンドブック完全版.秋山徹,河府和義,奥山隆平編2010
- Author(s)
  瓦林毅
- Publisher
  羊土社,東京
- Data Source
  KAKENHI-PROJECT-21591069
[Book] 新しい診断と治療のABC66認知症2010
- Author(s)
  瓦林毅, 東海林幹夫
- Total Pages
  13
- Publisher
  最新医学社
- Data Source
  KAKENHI-PROJECT-21591069
[Book] 新しい診断と治療のABC66認知症(三村将編集)検査所見2.生化学的マーカ2010
- Author(s)
  瓦林毅,東海林幹夫
- Publisher
  最新医学社大阪
- Data Source
  KAKENHI-PROJECT-21591069
[Book] 疾患モデルマウス・ラット活用ハンドブック完全版2010
- Author(s)
  瓦林毅
- Total Pages
  23
- Publisher
  羊土社
- Data Source
  KAKENHI-PROJECT-21591069
[Book] MCIと認知症-リスクファクター- Annual Review 2009 神経(柳澤信夫, 篠原幸人, 岩田誠, 清水輝夫, 寺本明編)2009
- Author(s)
  瓦林毅, 東海林幹夫
- Publisher
  中外医学社
- Data Source
  KAKENHI-PROJECT-19590976
[Book] MCIと認知症-リスクファクター-Annual Review 2009神経2009
- Author(s)
  瓦林毅, 東海林幹夫
- Publisher
  中外医学社
- Data Source
  KAKENHI-PROJECT-19590976
[Book] 脳卒中はどんな症状ではじまるのか, からだの科学2009
- Author(s)
  東海林幹夫, 清野祐輔, 若佐谷保仁, 瓦林毅
- Publisher
  日本評論社
- Data Source
  KAKENHI-PROJECT-19590976
[Book] MCIと認知症-リスクファクタ-Annual Review 2009神経2009
- Author(s)
  瓦林毅,東海林幹夫
- Publisher
  中外医学社,東京
- Data Source
  KAKENHI-PROJECT-21591069
[Book] 特殊なアルツハイマー病遺伝性脳アミロイドーシス、アイスランドタイプ遺伝性脳出血(HCHWA-I)日本臨床66巻増刊号1(通巻第929号)アルツハイマー病2008
- Author(s)
  瓦林毅
- Publisher
  日本臨床社
- Data Source
  KAKENHI-PROJECT-19590976
[Book] 特殊なアルツハイマー病遺伝性脳アミロイドーシス、ダッチタイプ遺伝性脳出血(HCHWA-D)日本臨床66巻増刊号1(通巻第929号)アルツハイマー病2008
- Author(s)
  瓦林毅
- Publisher
  日本臨床社
- Data Source
  KAKENHI-PROJECT-19590976
[Book] MCIと認知症-リスクファクター, AnnualReview神経20092008
- Author(s)
  瓦林毅, 東海林幹夫
- Publisher
  南江堂
- Data Source
  KAKENHI-PROJECT-19390233
[Book] 軽度認知症障害(MCI):認知症に先手を打つ 5.生物学的マーカー.2007
- Author(s)
  瓦林毅, 東海林幹夫
- Total Pages
  15
- Publisher
  中外医学社
- Data Source
  KAKENHI-PROJECT-19590976
[Book] Alzheimer 病のバイオマーカー(岩坪威編別冊)2007
- Author(s)
  瓦林毅, 東海林幹夫
- Publisher
  医学のあゆみ医歯薬出版株式会社
- Data Source
  KAKENHI-PROJECT-19590976
[Book] 軽度認知障害(pp47-59)2007
- Author(s)
  瓦林毅, 東海林幹夫
- Total Pages
  293
- Publisher
  中外医学社,東京
- Data Source
  KAKENHI-PROJECT-19390233
[Book] 神経難病のすべて〜症状・診断から最先端治療, 福祉の実際まで(pp34-43)2007
- Author(s)
  瓦林毅, 東海林幹夫
- Total Pages
  389
- Publisher
  新興医学,東京
- Data Source
  KAKENHI-PROJECT-19390233
[Book] アルツハイマー病. 神経難病のすべて~症状・診断から最先端治療福祉の実際まで(阿部康二)2007
- Author(s)
  瓦林毅, 東海林幹夫
- Publisher
  新興医学
- Data Source
  KAKENHI-PROJECT-19590976
[Book] 別冊医学のあゆみ Alzheimer病のバイオマーカー2007
- Author(s)
  瓦林毅, 東海林幹夫
- Total Pages
  6
- Publisher
  医歯薬出版株式会社
- Data Source
  KAKENHI-PROJECT-19590976
[Book] 医学のあゆみ, 別冊(pp71-76)2007
- Author(s)
  瓦林毅, 東海林幹夫
- Total Pages
  131
- Publisher
  医歯薬出版株式会社,東京
- Data Source
  KAKENHI-PROJECT-19390233
[Book] 神経難病のすべて〜症状・診断から最先端治療フルツハイマー病.2007
- Author(s)
  瓦林毅, 東海林幹夫
- Total Pages
  10
- Publisher
  新興医学
- Data Source
  KAKENHI-PROJECT-19590976
[Journal Article] Plasma ApoE4 Levels Are Lower than ApoE2 and ApoE3 Levels, and Not Associated with Plasma Aβ 40/42 Ratio as a Biomarker of Amyloid-β Amyloidosis in Alzheimer’s Disease2023
- Author(s)
  Nakamura Takumi、Kawarabayashi Takeshi、Ueda Tetsuya、Shimomura Sachiko、Hoshino Masaki、Itoh Ken、Ihara Kazushige、Nakaji Shigeyuki、Takatama Masamitsu、Ikeda Yoshio、Shoji Mikio
- Journal Title
  
  Journal of Alzheimer's Disease
  
  Volume: Online ahead of print Issue: 1 Pages: 1-16
- DOI
  10.3233/jad-220996
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22K07511
[Journal Article] Annual stability of the plasma A?40/42 ratio and associated factors2023
- Author(s)
  Nakamura Takumi、Kawarabayashi Takeshi、Nakahata Naoko、Itoh Ken、Ihara Kazushige、Nakaji Shigeyuki、Ikeda Yoshio、Takatama Masamitsu、Shoji Mikio
- Journal Title
  
  Annals of Clinical and Translational Neurology
  
  Volume: 10 Issue: 6 Pages: 879-891
- DOI
  10.1002/acn3.51770
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K07511
[Journal Article] Clinical Evaluation of Cerebrospinal Fluid p217tau and Neurofilament Light Chain Levels in Patients with Alzheimer’s Disease or Other Neurological Diseases2023
- Author(s)
  Kawarabayashi Takeshi、Nakamura Takumi、Miyashita Kazuya、Segawa Tatsuya、Fukamachi Isamu、Sugawara Takashi、Oka Hironori、Ishizawa Kunihiko、Amari Masakuni、Kasahara Hiroo、Makioka Kouki、Ikeda Yoshio、Takatama Masamitsu、Shoji Mikio
- Journal Title
  
  Journal of Alzheimer's Disease
  
  Volume: 96 Issue: 4 Pages: 1623-1638
- DOI
  10.3233/jad-230419
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K07511
[Journal Article] リピドラフトはアミロイドbeta蛋白蓄積による神経障害の共通したプラットフォームである2023
- Author(s)
  瓦林毅，東海林幹夫，甘利雅邦，菅原隆，岩崎理，岡大典，高玉真光
- Journal Title
  
  群馬医学
  
  Volume: 118 Pages: 31-37
- Data Source
  KAKENHI-PROJECT-22K07511
[Journal Article] Lipid Rafts Act as a Common Platform for Amyloid-β Oligomer-Induced Alzheimer’s Disease Pathology2022
- Author(s)
  Kawarabayashi Takeshi、Nakamura Takumi、Sato Kaoru、Seino Yusuke、Ichii Sadanobu、Nakahata Naoko、Takatama Masamitsu、Westaway David、George-Hyslop Peter St.、Shoji Mikio
- Journal Title
  
  Journal of Alzheimer's Disease
  
  Volume: 87 Issue: 3 Pages: 1189-1203
- DOI
  10.3233/jad-215662
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K07511
[Journal Article] フレイル対策におけるMCIの予防と治療2021
- Author(s)
  瓦林毅　東海林幹夫
- Journal Title
  
  Bio Clinica
  
  Volume: 36 Pages: 22-26
- Data Source
  KAKENHI-PROJECT-19K07989
[Journal Article] Quantitative Measurement of Cerebrospinal Fluid Amyloid-β Species by Mass Spectrometry2021
- Author(s)
  Seino Yusuke、Nakamura Takumi、Harada Tomoo、Nakahata Naoko、Kawarabayashi Takeshi、Ueda Tetsuya、Takatama Masamitsu、Shoji Mikio
- Journal Title
  
  Journal of Alzheimer's Disease
  
  Volume: 79 Issue: 2 Pages: 573-584
- DOI
  10.3233/jad-200987
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K07989, KAKENHI-PROJECT-18K07385
[Journal Article] Spastic Paraplegia with Paget's Disease of Bone due to a <i>VCP</i> Gene Mutation2021
- Author(s)
  Nakamura Takumi、Kawarabayashi Takeshi、Koh Kishin、Takiyama Yoshihisa、Ikeda Yoshio、Shoji Mikio
- Journal Title
  
  Intern. Med.
  
  Volume: 60 Issue: 1 Pages: 141-144
- DOI
  10.2169/internalmedicine.4617-20
- NAID
  130007965378
- ISSN
  0918-2918, 1349-7235
- Year and Date
  2021-01-01
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K07989, KAKENHI-PROJECT-19K16910
[Journal Article] IgG4-related hypothalamo-hypophysitis2021
- Author(s)
  Urushida Y, Ishikawa D, Yanaizumi M, Nakamura T, Amari M, Kawarabayashi T, Tosaka M, Ikeda Y, Takatama M, Shoji M
- Journal Title
  
  eNeurologicalSci
  
  Volume: 24 Pages: 100362-100362
- DOI
  10.1016/j.ensci.2021.100362
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K07989
[Journal Article] Improved Neuroimaging Findings and Cognitive Function in a Case of High-altitude Cerebral Edema2021
- Author(s)
  Urushida Y, Kikuchi Y, Shimizu C, Amari M, Kawarabayashi T, Nakamura T, Ikeda Y, Takatama M, Shoji M
- Journal Title
  
  Intern. Med.
  
  Volume: 60 Issue: 8 Pages: 1299-1302
- DOI
  10.2169/internalmedicine.5747-20
- NAID
  130008025067
- ISSN
  0918-2918, 1349-7235
- Year and Date
  2021-04-15
- Language
  English
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K07989
[Journal Article] Age-Related Cognitive Decline and Prevalence of Mild Cognitive Impairment in the Iwaki Health Promotion Project2021
- Author(s)
  Nakahata N, Nakamura T, Kawarabayashi T, Seino Y, Ichii S, Ikeda Y, Amari M, Takatama M, Murashita K, Ihara K, Itoh K, Nakaji S, Shoji M
- Journal Title
  
  Journal of Alzheimer's Disease
  
  Volume: 84 Issue: 3 Pages: 1233-1245
- DOI
  10.3233/jad-210699
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K07989
[Journal Article] Successful basilar artery dilatation in pure bilateral cerebral peduncular infarctions using balloon angioplasty2020
- Author(s)
  Kikuchi Yutaro、Miyamoto Naoko、Urushida Yuki、Shimizu Chisato、Amari Masakuni、Kawarabayashi Takeshi、Nakamura Takumi、Takatama Shin、Naito Isao、Ikeda Yoshio、Takatama Masamitsu、Shoji Mikio
- Journal Title
  
  eNeurologicalSci
  
  Volume: 21 Pages: 100282-100282
- DOI
  10.1016/j.ensci.2020.100282
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K07989
[Journal Article] An autopsy case of primary lateral sclerosis with Alzheimer's disease.2020
- Author(s)
  Nakamura T, Kon T, Kawarabayashi T, Wakabayashi K, Ikeda Y, Shoji M.
- Journal Title
  
  J Neurol Sci.
  
  Volume: 412 Pages: 116792-116792
- DOI
  10.1016/j.jns.2020.116792
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K07385, KAKENHI-PROJECT-19K07989, KAKENHI-PROJECT-18H02533
[Journal Article] CogEvo, a cognitive function balancer, is a sensitive and easy psychiatric test battery for age-related cognitive decline.2020
- Author(s)
  Ichii S, Nakamura T, Kawarabayashi T, Takatama M, Ohgami T, Ihara K, Shoji M.
- Journal Title
  
  Geriatr Gerontol Int.
  
  Volume: 20(3) Issue: 3 Pages: 248-255
- DOI
  10.1111/ggi.13847
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K07385, KAKENHI-PROJECT-19K07989
[Journal Article] Novel ELISAs to measure total and phosphorylated tau in cerebrospinal fluid.2020
- Author(s)
  Kawarabayashi T, Nakamura T, Miyashita K, Fukamachi I, Seino Y, Shoji M.
- Journal Title
  
  Neurosci Lett.
  
  Volume: 722 Pages: 134826-134826
- DOI
  10.1016/j.neulet.2020.134826
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K07385, KAKENHI-PROJECT-19K07989
[Journal Article] Cerebrospinal Fluid and Plasma Biomarkers in Neurodegenerative Diseases2019
- Author(s)
  Seino Yusuke、Nakamura Takumi、Kawarabayashi Takeshi、Hirohata Mie、Narita Sakiko、Wakasaya Yasuhito、Kaito Kozue、Ueda Tetsuya、Harigaya Yasuo、Shoji Mikio
- Journal Title
  
  Journal of Alzheimer's Disease
  
  Volume: 68 Issue: 1 Pages: 395-404
- DOI
  10.3233/jad-181152
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K07385, KAKENHI-PROJECT-19K07989
[Journal Article] Perineuritis Successfully Treated with Early Aggressive Immunotherapy2019
- Author(s)
  Nakamura T, Kawarabayashi T, Seino Y, Hirohata M, Wakabayashi K, Shoji M.
- Journal Title
  
  Intern. Med.
  
  Volume: 58 Issue: 19 Pages: 2875-2878
- DOI
  10.2169/internalmedicine.2638-19
- NAID
  130007722424
- ISSN
  0918-2918, 1349-7235
- Year and Date
  2019-10-01
- Language
  English
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K07385, KAKENHI-PROJECT-19K07989, KAKENHI-PROJECT-18H02533
[Journal Article] Oral Immunization with Soybean Storage Protein Containing Amyloid-β 4-10 Prevents Spatial Learning Decline.2019
- Author(s)
  Kawarabayashi T, Terakawa T, Takahashi A, Hasegawa H, Narita S, Sato K, Nakamura T, Seino Y, Hirohata M, Baba N, Ueda T, Harigaya Y, Kametani F, Maruyama N, Ishimoto M, St George-Hyslop P, Shoji M.
- Journal Title
  
  J Alzheimers Dis.
  
  Volume: 70(2) Issue: 2 Pages: 487-503
- DOI
  10.3233/jad-190023
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K07385, KAKENHI-PROJECT-19K07989
[Journal Article] Case of elderly-onset multiple acyl-CoA dehydrogenase deficiency with a novel ETFDH mutation shows progressive muscle weakness and rhabdomyosis2018
- Author(s)
  Seino Y, Nakamura T, Kawarabayashi T, Wakasaya Y, Hayashi YK, Okubo M, Nishino I, Shoji M
- Journal Title
  
  Neurology and Clinical Neuroscience
  
  Volume: 印刷中
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K09305
[Journal Article] Disappearance of MRI imaging signals in a patient with neuronal intranuclear inclusion disease2018
- Author(s)
  Kawarabayashi T, Nakamura T, Seino Y, Hirohata M, Mori F, Wakabayashi K, Ono S, Harigaya Y, Shoji M
- Journal Title
  
  J Neurol Sci
  
  Volume: 388 Pages: 1-3
- DOI
  10.1016/j.jns.2018.02.038
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15K09305, KAKENHI-PROJECT-15K09306, KAKENHI-PROJECT-17K07088
[Journal Article] Case of elderly-onset multiple acyl-CoA dehydrogenase deficiency with a novel ETFDH mutation shows progressive muscle weakness and rhabdomyosis2018
- Author(s)
  Seino Y, Nakamura T, Kawarabayashi T, Wakasaya Y, Hayashi YK, Okubo M, Nishino I, Shoji M
- Journal Title
  
  Neurology and Clinical Neuroscience
  
  Volume: 6 Issue: 2 Pages: 39-41
- DOI
  10.1111/ncn3.12177
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15K09306
[Journal Article] アルツハイマー病治療薬開発　抗アミロイド抗体治療2017
- Author(s)
  瓦林毅　東海林幹夫
- Journal Title
  
  日本臨床
  
  Volume: 2017年12月増刊
- Data Source
  KAKENHI-PROJECT-15K09305
[Journal Article] Alzheimer型認知症治療の現状2017
- Author(s)
  瓦林毅　東海林幹夫
- Journal Title
  
  Geriatric Medicine
  
  Volume: 55
- Data Source
  KAKENHI-PROJECT-15K09305
[Journal Article] A case of hereditary neuropathy with liability to pressure palsies due to push-up exercise2017
- Author(s)
  Nakamura T, Kawarabayashi T, Seino Y, Shoji M
- Journal Title
  
  Rinsho Shinkeigaku
  
  Volume: 57 Issue: 7 Pages: 383-386
- DOI
  10.5692/clinicalneurol.cn-001023
- NAID
  130005873378
- ISSN
  0009-918X, 1882-0654
- Language
  Japanese
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15K09306
[Journal Article] 進行中のアルツハイマー病臨床治験および予防介入試験2017
- Author(s)
  瓦林毅　東海林幹夫
- Journal Title
  
  実験医学
  
  Volume: 35
- Data Source
  KAKENHI-PROJECT-15K09305
[Journal Article] 遺伝が関与する認知症　主な認知症と遺伝子との関連についてレビー小体型認知症2017
- Author(s)
  瓦林毅　東海林幹夫
- Journal Title
  
  認知症の最新治療
  
  Volume: 7 Pages: 74-80
- Data Source
  KAKENHI-PROJECT-15K09305
[Journal Article] Increases in plasma Abeta40 levels and the Abeta 40/42 ratio in patients with diabetes mellitus and dementia2016
- Author(s)
  Ueno Y, Nagaoka M, Nakamura T, Abe N, Nakata T, Wakasaya Y, Matsubara E, Kawarabayashi T, Shoji M
- Journal Title
  
  Hiroski Medical J
  
  Volume: 66 Pages: 110-119
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K09306
[Journal Article] Increases in plasma Abeta40 levels and the Abeta40/42 ratio in patients with diabetes mellitus and dementia．2016
- Author(s)
  Ueno Y, Nagaoka M, Nakamura T, Abe N, Nakata T, Wakasaya Y, Matsubara E, Kawarabayashi T, Shoji M
- Journal Title
  
  Hirosaki Medical J
  
  Volume: 66 Pages: 110-119
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K09305
[Journal Article] 認知症の血液・髄液診断マーカー．2015
- Author(s)
  瓦林毅　東海林幹夫
- Journal Title
  
  Mebio
  
  Volume: ３２ Pages: 36-45
- Data Source
  KAKENHI-PROJECT-15K09305
[Journal Article] 認知症の血液・髄液診断マーカー2015
- Author(s)
  瓦林毅　東海林幹夫
- Journal Title
  
  Mobil
  
  Volume: 32 Pages: 36-45
- Data Source
  KAKENHI-PROJECT-15K09306
[Journal Article] Necklace cytoplasmic bodies in hereditary myopathy with early respiratory failure.2015
- Author(s)
  Uruha A, Hayashi YK, Oya Y, Mori-Yoshimura M, Kanai M, Murata M, Kawamura M, Ogata K, Matsumura T, Suzuki S, Takahashi Y, Kondo T, Kawarabayashi T, Ishii Y, Kokubun N, Yokoi S, Yasuda R, Kira JI, Mitsuhashi S, Noguchi S, Nonaka I, Nishino I
- Journal Title
  
  J Neurol Neurosurg Psychiatry
  
  Volume: 86 Issue: 5 Pages: 483-489
- DOI
  10.1136/jnnp-2014-309009
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24591246
[Journal Article] 認知症の血液・髄液診断マーカー2015
- Author(s)
  瓦林毅，東海林幹夫
- Journal Title
  
  Mebio
  
  Volume: 32
- Data Source
  KAKENHI-PROJECT-24591246
[Journal Article] 神経疾患治療の進歩2013年認知症の治療の進歩2014
- Author(s)
  瓦林毅
- Journal Title
  
  神経治療学
  
  Volume: 31 Pages: 378-381
- Data Source
  KAKENHI-PROJECT-24591246
[Journal Article] Stable accumulation of seed storage proteins containing vaccine peptides in transgenic soybean seeds2014
- Author(s)
  Maruyama N, Fujiwara K, Yokoyama K, Cerrone C, Hasegawa H, Takagi K, Nishizawa K, Uki Y, Kawarabayashi T, Shouji Y, Ishimoto M, Terakawa T
- Journal Title
  
  Journal of Bioscience and Bioengineering
  
  Volume: 未定
- NAID
  110009865428
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24591246
[Journal Article] Lack of Genetic Association Between TREM2 and Late-Onset Alzheimer's Disease in a Japanese Population2014
- Author(s)
  Miyashita A, Wen Y, Kitamura N, Matsubara E, Kawarabayashi T, Shoji M, et al
- Journal Title
  
  J Alzheimers Dis
  
  Volume: 未定
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24591246
[Journal Article] アルツハイマー病診断のバイオマーカー－最近の進歩－　血液・CSF中のアミロイドタンパクとタウタンパクおよびリン酸化タウ2013
- Author(s)
  瓦林毅　東海林幹夫
- Journal Title
  
  老年精神医学雑誌
  
  Volume: 24 Pages: 119-124
- Data Source
  KAKENHI-PROJECT-24591246
[Journal Article] SORL1 Is Genetically Associated with Late-Onset Alzheimer’s Disease in Japanese, Koreans and Caucasians2013
- Author(s)
  Miyashita A, Koike A, Jun G, Kawarabayashi T, Shoji M,Arai H, Asada T, Harigaya Y, Ikeda M, Amari M, Ikeuchi T, St. George-Hyslop P,
- Journal Title
  
  PLoS One
  
  Volume: 8 Issue: 4 Pages: e58618-e58618
- DOI
  10.1371/journal.pone.0058618
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23591231, KAKENHI-PROJECT-23591234, KAKENHI-PROJECT-23591706, KAKENHI-PROJECT-23659450, KAKENHI-PROJECT-24310144, KAKENHI-PROJECT-24500431, KAKENHI-PROJECT-24510275, KAKENHI-PROJECT-24591246, KAKENHI-PROJECT-25670415, KAKENHI-PROJECT-221S0002, KAKENHI-PLANNED-22129004
[Journal Article] 神経疾患治療の進歩2012年認知症の治療の進歩2013
- Author(s)
  瓦林毅
- Journal Title
  
  神経治療学
  
  Volume: 30 Pages: 392-396
- Data Source
  KAKENHI-PROJECT-24591246
[Journal Article] 認知症と臨床検査認知症の病態2012
- Author(s)
  瓦林毅, 東海林幹夫
- Journal Title
  
  臨床検査
  
  Volume: 56 Pages: 22-30
- Data Source
  KAKENHI-PROJECT-21591069
[Journal Article] 認知症と臨床検査認知症の病態2012
- Author(s)
  瓦林毅, 東海林幹夫
- Journal Title
  
  臨床検査
  
  Volume: 56 Pages: 22-30
- Data Source
  KAKENHI-PROJECT-21591069
[Journal Article] 認知症の診断：アルツハイマー病(AD)を中心に AD診断におけるバイオマーカー2012
- Author(s)
  瓦林毅　東海林幹夫
- Journal Title
  
  Progress in Medicine
  
  Volume: 32 Pages: 2557-2562
- Data Source
  KAKENHI-PROJECT-24591246
[Journal Article] Sortilin is required for toxic action of Aβ oligomers (AβOs): Extracellular AβOs trigger apoptosis, and intraneuronal AβOs impair degradation pathways2012
- Author(s)
  Ayumi Takamura
- Journal Title
  
  Life Sciences
  
  Volume: 91 Issue: 23-24 Pages: 1177-1186
- DOI
  10.1016/j.lfs.2012.04.038
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23659449, KAKENHI-PROJECT-23659450, KAKENHI-PROJECT-24591246
[Journal Article] An unusual case of elderly-onset cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy (CADASIL) with multiple cerebrovascular risk factors.2012
- Author(s)
  Watanabe M, Adachi Y, Jackson M, Yamamoto-Watanabe Y, Wakasaya Y, Shirahama I, Takamura A, Matsubara E, Kawarabayashi T, Shoji M
- Journal Title
  
  J Stroke Cerebrovasc Dis
  
  Volume: 21(2) Pages: 143-5
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23659450
[Journal Article] Sortilin is required for toxic action of Aβ oligomers (AβOs) : Extracellular AβOs trigger apoptosis,and intraneuronal AβOs impair degradation pathways2012
- Author(s)
  Takamura A, Sato Y, Watabe D, Okamoto Y, Nakata T, Kawarabayashi T, Oddo S, Laferla FM, Shoji M, Matsubara E
- Journal Title
  
  Life Sci
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591069
[Journal Article] 神経疾患治療の進歩2011年認知症の治療の進歩2012
- Author(s)
  瓦林毅
- Journal Title
  
  神経治療学
  
  Volume: 29 Pages: 375-379
- Data Source
  KAKENHI-PROJECT-24591246
[Journal Article] 認知症と臨床検査　認知症の病態2012
- Author(s)
  瓦林毅　東海林幹夫
- Journal Title
  
  臨床検査
  
  Volume: 56 Pages: 22-30
- Data Source
  KAKENHI-PROJECT-24591246
[Journal Article] Extracellular and intraneuronal HMW-AβOs represent a molecular basis of memory loss in Alzheimer's disease model mouse2011
- Author(s)
  Takamura A, Okamoto Y, Kawarabayashi T, Yokoseki T, Shibata M, Mouri A, Nabeshima T, Sun H, Abe K, Urisu T, Yamamoto N, Shoji M, Yanagisawa K, Michikawa M, Matsubara E
- Journal Title
  
  Mol Neurodegener
  
  Volume: 6 Pages: 20-20
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591069
[Journal Article] Factors responsible for neurofibrillary tangles and neuronal cell losses in tauopathy.2011
- Author(s)
  Wakasaya Y, Kawarabayashi T, Watanabe M, Yamamoto-Watanabe Y, Takamura A, Kurata T, Murakami T, Abe K, Yamada K, Wakabayashi K, Sasaki A, Westaway D, Hyslop PS, Matsubara E, Shoji M
- Journal Title
  
  J Neurosci Res
  
  Volume: 89(4) Issue: 4 Pages: 576-84
- DOI
  10.1002/jnr.22572
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23659450
[Journal Article] Factors responsible for neurofibrillary tangles and neuronal cell losses in tauopathy2011
- Author(s)
  Wakasaya Y, Kawarabayashi T, Watanabe M, Yamamoto-Watanabe Y, Takamura A, Kurata T, Murakami T, Abe K, Yamada K, Wakabayashi K, Sasaki A, Westaway D, St.George-Hyslop P, Matsubara E, Shoji M
- Journal Title
  
  J Neurosci Res
  
  Volume: 89 Pages: 576-584
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591069
[Journal Article] Interferon β-1b皮下注射針の違い.による検討 27ゲージ針と30ゲージ針の比較2011
- Author(s)
  鈴木千恵子, 冨山誠彦, 瓦林毅, 馬場正之, 東海林幹夫
- Journal Title
  
  神経内科
  
  Volume: 74 Pages: 509-511
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591069
[Journal Article] Dissociation of Aβ from lipoprotein in cerebrospinal fluid from Alzheimer's disease accelerates Aβ42 assembly2011
- Author(s)
  Takamura A, Kawarabayashi T, Yokoseki T, Shibata M, Morishima-Kawashima M, Saito Y, Murayama S, Ihara Y, Abe K, Shoji M, Michikawa M, Matsubara E
- Journal Title
  
  J Neurosci Res
  
  Volume: 89 Pages: 815-821
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591069
[Journal Article] Extracellular and intraneuronal HMW-AbetaOs represent a molecular basis of memory loss in Alzheimer's disease model mouse2011
- Author(s)
  Takamura A, Okamoto Y, Kawarabayashi T, Yokoseki T, Shibata M, Mouri A, Nabeshima T, Sun H, Abe K, Urisu T, Yamamoto N, Shoji M, Yanagisawa K, Michikawa M, Matsubara E
- Journal Title
  
  Mol Neurodegener
  
  Volume: 6 Issue: 1 Pages: 20-20
- DOI
  10.1186/1750-1326-6-20
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591069, KAKENHI-PROJECT-22300118, KAKENHI-PROJECT-23659449, KAKENHI-PROJECT-23659450
[Journal Article] 神経疾患治療の進歩2010年認知症の治療の進歩2011
- Author(s)
  瓦林毅, 東海林幹夫
- Journal Title
  
  神経治療学
  
  Volume: 28 Pages: 347-350
- Data Source
  KAKENHI-PROJECT-21591069
[Journal Article] Dissociation of beta-amyloid from lipoprotein in cerebrospinal fluid from Alzheimer' s disease accelerates beta-amyloid-422011
- Author(s)
  Takamura A, Kawarabayashi T, Yokoseki T, Shibata M, Morishima-Kawashima M, Saito Y, Murayama S, Ihara Y, Abe K, Shoji M, Michikawa M, Matsubara E
- Journal Title
  
  assembly. Neurosci Res
  
  Volume: 89 Issue: 6 Pages: 815-821
- DOI
  10.1002/jnr.22615
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21500343, KAKENHI-PROJECT-21591069, KAKENHI-PROJECT-22300118, KAKENHI-PROJECT-23659450
[Journal Article] アルツハイマー病の免疫療法2011
- Author(s)
  瓦林毅, 東海林幹夫
- Journal Title
  
  Mebio
  
  Volume: 28(5) Pages: 114-126
- Data Source
  KAKENHI-PROJECT-21591069
[Journal Article] 認知症研究に用いられる動物・細胞実験モデル遺伝子改変モデルAPPIPS-12011
- Author(s)
  瓦林毅
- Journal Title
  
  日本臨床
  
  Volume: 印刷中
- Data Source
  KAKENHI-PROJECT-21591069
[Journal Article] Aβ amyloid accelerates accumulation of phosphorylated tau in neuronal cytoplasm and processes of double transgenic mice2010
- Author(s)
  Seino Y, Kawarabayashi T, Wakasaya Y, Takamura A, Nakahata N, Watanabe M, Yamamoto-Watanabe Y, Matsubara E, Westaway D, Davis P, St.George-Hyslop P, Shoji M
- Journal Title
  
  J Neurosci Res
  
  Volume: 88 Pages: 3547-3554
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591069
[Journal Article] 神経疾患治療の進歩2009年認知症の治療の進歩2010
- Author(s)
  瓦林毅, 東海林幹夫
- Journal Title
  
  神経治療学
  
  Volume: 27 Pages: 493-498
- Data Source
  KAKENHI-PROJECT-21591069
[Journal Article] An unusual case of elderly-onset CADASIL with multiple cerebrovascular risk factors2010
- Author(s)
  Watanabe M, Adachi Y, Jackson M, Yamamoto-Watanabe Y, Wakasaya Y, Shirahama I, Takamura A, Matsubara E, Kawarabayashi T, Shoji M
- Journal Title
  
  J Stroke Cerebrovasc Dis
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591069
[Journal Article] Prevalence of autosomal dominant cerebellar ataxia in Aomori, the northernmost prefecture of Honshu, Japan2010
- Author(s)
  Yamamoto-Watanabe Y, Watanabe M, Hikichi M, Ikeda Y, Jackson M, Wakasaya Y, Matsubara E, Kawarabayashi T, Kannari K, Shoji M
- Journal Title
  
  Internal Med
  
  Volume: 49 Pages: 2409-2414
- NAID
  130000413368
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591069
[Journal Article]2010
- Author(s)
  瓦林毅, 東海林幹夫
- Journal Title
  
  新しい診断と治療のABC 66認知症(最新医学社)
  
  Pages: 148-160
- Data Source
  KAKENHI-PROJECT-21591069
[Journal Article] PAとPSPの重要な鑑別点.2010
- Author(s)
  倉田智子, 林健, 宮崎一徳, 森本展年, 大田泰之, 竹久康, 永井真貴子, 瓦林毅, 神谷達司, 東海林幹夫, 阿部康二, 高尾芳樹, 大田泰正, 針谷康夫, 真邊康宏
- Journal Title
  
  老年期認知症研究会誌
  
  Volume: 16 Pages: 125-131
- Data Source
  KAKENHI-PROJECT-21591069
[Journal Article] A Japanese ALS6 family with mutation R521C in the FUS/TLS gene : a clinical, pathological and genetic report.2010
- Author(s)
  Yamamoto-Watanabe Y, Watanabe M, Okamoto K, Fujita Y, Jackson M, Ikeda M, Nakazato Y, Ikeda Y, Matsubara E, Kawarabayashi T, Shoji M
- Journal Title
  
  J Neurol Sci.
  
  Volume: 296 Pages: 59-63
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591069
[Journal Article] 神経疾患治療の進歩認知症の治療の進歩2010
- Author(s)
  瓦林毅, 東海林幹夫
- Journal Title
  
  神経治療学
  
  Volume: 27 Pages: 493-498
- Data Source
  KAKENHI-PROJECT-21591069
[Journal Article] 脳卒中はどんな症状で始まるのか。2010
- Author(s)
  瓦林毅, 東海林幹夫
- Journal Title
  
  全薬ジャーナル
  
  Volume: 253 Pages: 14-17
- Data Source
  KAKENHI-PROJECT-21591069
[Journal Article] Factors responsible for neurofibrillary tangles and neuronal cell losses in tauopathy.2010
- Author(s)
  Wakasaya Y, Kawarabayashi T, Watanabe M, Yamamoto-Watanabe Y, Takamura A, Kura ta T, Murakami T, Abe K, Y amada K, Wakabayashi K, Sasaki A, Westaway D, St.Geor ge-Hyslop P, Matsubara E, Shoji M
- Journal Title
  
  J Neurosci Res
  
  Volume: Epub ahea d of print
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591069
[Journal Article] Quantification of cystatin C in cerebrospinal fluid from various neurological disorders and correlation with G73A polymorphism in CST3.2010
- Author(s)
  Yamamoto-Watanabe Y, Watanabe M, Jackson M, Akimoto H, Sugimoto K, Yasujima M, Wakasaya Y, Matsubara E, Kawarabayashi T, Harigaya Y, Lyndon AR, Shoji M
- Journal Title
  
  Brain Res
  
  Volume: 1361 Pages: 140-145
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591069
[Journal Article] 神経疾患治療の進歩認知症の治療の進歩 2009.2010
- Author(s)
  瓦林毅, 東海林幹夫
- Journal Title
  
  神経治療学 (in press)
- Data Source
  KAKENHI-PROJECT-21591069
[Journal Article] Quantification of cystatin C in cerebrospinal fluid from various neurological disorders and correlation with G73A polymorphism in CST32010
- Author(s)
  Yamamoto-Watanabe Y, Watanabe M, Jackson M, Akimoto H, Sugimoto K, Yasujima M, Wakasaya Y, Matsubara E, Kawarabayashi T, Harigaya Y, Lyndon AR, Shoji M
- Journal Title
  
  Brain Res
  
  Volume: 1361 Pages: 140-145
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591069
[Journal Article] A Japanese ALS6 family with mutation R521C in the FUS/TLS gene a clinical, pathological and genetic report2010
- Author(s)
  Yamamoto-Watanabe Y, Watanabe M, Okamoto K, Fujita Y, Jackson M, Ikeda M, Nakazato Y, Ikeda Y, Matsubara E, Kawarabayashi T, Shoji M
- Journal Title
  
  J Neurol Sci
  
  Volume: 296 Pages: 59-63
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591069
[Journal Article] Prevalence of autosomal dominant cerebellar ataxia in Aomori, the northernmost prefbcture of Honshu, Japan.2010
- Author(s)
  Yamamoto-Watanabe Y, Watanabe M, Hikichi M, Ikeda Y, Jackson M, Wakasaya Y, Matsubara E, Kawarabayashi T, Kannari K, Shoji M
- Journal Title
  
  Internal Med
  
  Volume: 49 Pages: 2409-2414
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591069
[Journal Article] Aβ amyloid accelerates accumulation of phosphorylated tau in neuronal cytoplasm and processes of double transgenic mice.2010
- Author(s)
  Seino Y, Kawarabayashi T, Wakasaya Y, Takamura A, Nakahata N, Watanabe M, Yamamoto-Watanabe Y, Matsubara E, Westaway D, Davis P, St.George-Hyslon P, Shaji
- Journal Title
  
  J Neurosci Res
  
  Volume: 88 Pages: 3547-3554
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591069
[Journal Article] 血管因子からみた認知症 Up To Date:生活習慣病とアルツハイマー型認知症2010
- Author(s)
  瓦林毅, 東海林幹夫
- Journal Title
  
  分子脳血管病
  
  Volume: 9 Pages: 154-159
- Data Source
  KAKENHI-PROJECT-21591069
[Journal Article] 血管因子からみた認知症Up To Date:生活習慣病とアルツハイマー型認知症。2010
- Author(s)
  瓦林毅, 東海林幹夫
- Journal Title
  
  分子脳血管病
  
  Volume: 9 Pages: 154-159
- Data Source
  KAKENHI-PROJECT-21591069
[Journal Article] An unusual case of chronic relapsing tetanus associated with man dibular osteomyelitis.2009
- Author(s)
  Wakasaya Y, Watanabe M, Tomiyama M, Suzuki C, Jackson M, Fujimuro M, Kimura T, Seino Y, Kawarabayashi T, Yamamoto-Watanabe Y, Matsubara E, Shirahama I, Takamura A, Nakahata N, Shoji M
- Journal Title
  
  Intern Med 48
  
  Pages: 1311-1313
- NAID
  130000121961
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591069
[Journal Article] A chemical chaperone, sodium 4-phenyl butyric acid, attenuates the pathogenic potency in human α-synuclein A30P+A53T transgenicmice. Parkinsonism Relat Disord2009
- Author(s)
  Ono K, Ikemoto M, Kawarabayashi T, Ikeda M, Nishinakagawa T, Hosokawa M, Shoji M, Takahashi M, Nakashima M
- Journal Title
  
  Epubahead of print
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590976
[Journal Article] A chemical chaperone, sodium 4-phenylbutyric acid, attenuate5 the pathogenic potency in human α-synuclein A30P+A53T transgenic mice2009
- Author(s)
  Ono K, Ikemoto M, Kawarabayashi T, Ikeda M, Nishinakagawa T, Hosokawa M, Shoji M, Takahashi M, Nakashima M
- Journal Title
  
  Parkinsonism Relat Disord (Epub ahead of print)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590976
[Journal Article] Motor impairment and aberrant production of neurochemicals in human α-synuclein A30P+A53T transgenic mice with α-synuclein pathology2009
- Author(s)
  Ikeda M, Kawarabayashi T, Harigaya Y, Sasaki A, Yamada S, Matsubara E, Murakami T, Tanaka Y, Kurata T, Wuhua X, Ueda K, Kuribara H, Ikarashi Y, Nakazato Y, Okamoto K, Abe K, Shoji M
- Journal Title
  
  Brain Res
  
  Volume: 1250 Pages: 232-241
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591069
[Journal Article]2009
- Author(s)
  瓦林毅, 東海林幹夫
- Journal Title
  
  Annual Review 2009神経(中外医学社)
  
  Pages: 184-196
- Data Source
  KAKENHI-PROJECT-21591069
[Journal Article] Motor impairment and aberrant production of neurochemicals in human α-synuclein A30P+A53T transgenic mice with α-synuclein pathology2009
- Author(s)
  Ikeda M, Kawarabayashi T, Harigaya Y, Sasaki A, Yamada S, Matsubara E, Murakami T, Tanaka Y, Kurata T, Wuhua X, Ueda K, Kuribara H, Ikarashi Y, Nakazato Y, Okamoto K, Abe K, Shoji M
- Journal Title
  
  Brain Res. 1250
  
  Pages: 232-241
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590976
[Journal Article] Motor impairment and aberrant production of neurochemicals in human alpha-synuclein A30P+A53T transgenic mice with alpha-synuclein pathology2009
- Author(s)
  Ikeda M, Kawarabayashi T, Harigaya Y, Sasaki A, Yamada S, Matsubara E, Murakami T, Tanaka Y, Kurata T, Wuhua X, Ueda K, Kuribara H, Ikarashi Y, Nakazato Y, Okamoto K, Abe K, Shoji M
- Journal Title
  
  Brain Res. 1250
  
  Pages: 232-41
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390233
[Journal Article] Motor impairment and aberrant production of neurochemicals in human a-synuclein A30P+A53T transgenic mice with α-synuclein pathology2009
- Author(s)
  Ikeda M, Kawarabayashi T. Harigaya Y, Sasaki A, Yamada S, Matsubara E, Murakami T, Tanaka Y, Kurata T, Wuhua X, Ueda K, Kuribara H, Ikarashi Y Nakazato Y, Okamoto K, Abe K, Shoji M
- Journal Title
  
  Brain Res 1250
  
  Pages: 232-241
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590976
[Journal Article] 神経疾患治療の進歩認知症の治療の進歩2009
- Author(s)
  瓦林毅, 東海林幹夫
- Journal Title
  
  神経治療学 (in press)
- Data Source
  KAKENHI-PROJECT-19590976
[Journal Article] ダッチタイプおよびアイスランドタイプ遺伝性脳出血.2009
- Author(s)
  瓦林毅
- Journal Title
  
  神経内科 70
  
  Pages: 172-179
- Data Source
  KAKENHI-PROJECT-21591069
[Journal Article] A chemical chaperone, sodium 4-phenylbutyric acid, attenuates the pathogenic potency in human α-synuclein A30P+A53T transgenic mice2009
- Author(s)
  Ono K, Ikemoto M, Kawarabayashi T, Ikeda M, Nishinakagawa T, Hosokawa M, Shoji M, Takahashi M, Nakashima M
- Journal Title
  
  J Neurosci Res
  
  Volume: 15 Pages: 649-654
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591069
[Journal Article] Motor impairment and aberrant production of neurochemicals in human α-synuclein A30P+A53T transgenic mice with α-synuclein pathology.2009
- Author(s)
  Ikeda M, Kawarabayashi T, Harigaya Y, Sasaki A, Yamada S, Matsubara E, Murakami T, Tanaka Y, Kurata T, Wuhua X, Ueda K, Kuribara H, Ikarashi Y, Nakazato Y, Okamoto K, Abe K, Shoji M
- Journal Title
  
  Brain Res 1250
  
  Pages: 232-241
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591069
[Journal Article]2009
- Author(s)
  瓦林毅, 東海林幹夫
- Journal Title
  
  MCIと認知症-リスクファクター-Annual Review 2009神経(柳澤信夫,篠原幸人,岩田誠,清水輝夫,寺本明編)(中外医学社)
  
  Pages: 184-196
- Data Source
  KAKENHI-PROJECT-19390233
[Journal Article] Transthyretin accelerates vascular Aβ deposition in a mouse model of Alzheimer's disease2009
- Author(s)
  Wati H, Kawarabayashi T, Matsubara E, Kasai A, Hirasawa T, Kubota T, Harigaya Y, Shoji M, Maeda S
- Journal Title
  
  Brain Pathol 19
  
  Pages: 48-57
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590976
[Journal Article] Motor impairment and aberrant production of neurochemicals in human alpha-synuclein A30P+A53T transgenic mice with alpha-synuclein pathology2009
- Author(s)
  Ikeda M, Kawarabayashi T, Harigaya Y, Sasaki A, Yamada S, Matsubara E, Murakami T, Tanaka Y, Kurata T, Wuhua X, Ueda K, Kuribara H, Ikarashi Y, Nakazato Y, Okamoto K, Abe K, Shoji M
- Journal Title
  
  Brain Res 1250
  
  Pages: 232-41
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390233
[Journal Article] 生活習慣病とアルツハイマー型認知症.2009
- Author(s)
  瓦林毅, 東海林幹夫
- Journal Title
  
  分子脳血管病 9
  
  Pages: 18-23
- Data Source
  KAKENHI-PROJECT-21591069
[Journal Article] 神経疾患治療の進歩認知症の治療の進歩2009
- Author(s)
  瓦林毅, 東海林幹夫
- Journal Title
  
  神経治療学
  
  Volume: 26 Pages: 445-449
- Data Source
  KAKENHI-PROJECT-21591069
[Journal Article] Transthyretin accelerates vascular Ass deposition in a mouse model of Alzheimer's disease.2009
- Author(s)
  Wati H, Kawarabayashi T, Matsubara E, Kasai A, Hirasawa T, Kubota T, Harigaya Y, Shoji M, Maeda S
- Journal Title
  
  Brain Pathol 19
  
  Pages: 48-57
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591069
[Journal Article] Transthyretiri accelerates vascular Aβ deposition in a mouse model of Alzheimer's disease2009
- Author(s)
  Wati H, Kawarabayashi T, Matsubara E, Kasai A, Hirasawa T, Kubota T, Harigaya Y, Shoji M, Maeda S
- Journal Title
  
  Brain Pathol 19
  
  Pages: 48-57
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590976
[Journal Article] 脳卒中はどんな症状ではじまるのか.2009
- Author(s)
  東海林幹夫, 清野祐輔, 若佐谷保仁, 瓦林毅
- Journal Title
  
  からだの科学 260
  
  Pages: 13-16
- Data Source
  KAKENHI-PROJECT-21591069
[Journal Article] An unusual case of chronic relapsing tetanus associated with mandibular osteomyelitis2009
- Author(s)
  Wakasaya Y, Watanabe M, Tomiyama M, Suzuki C, Jackson M, Fujimuro M, Kimura T, Seino Y, Kawarabayashi T, Yamamoto-Watanabe Y, Matsubara E, Shirahama I, Takamura A, Nakahata N, Shoji M
- Journal Title
  
  Intern Med
  
  Volume: 48 Pages: 1311-1313
- NAID
  130000121961
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591069
[Journal Article] A chemical chaperone, sodium 4-phenylbutyric acid, attenuates the pathogenic potency in human alpha-synuclein A30P+A53T transgenic mice2009
- Author(s)
  Ono K, Ikemoto M, Kawarabayashi T, Ikeda M, Nishinakagawa T, Hosokawa M, Shoji M, Takahashi M, Nakashima M
- Journal Title
  
  Parkinsonism Relat Disord. Apr 1. [Epub ahead of print] PubMed PMID : 19345133
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390233
[Journal Article] 神経疾患治療の進歩認知症の治療の進歩.2009
- Author(s)
  瓦林毅, 東海林幹夫
- Journal Title
  
  神経治療学 26
  
  Pages: 445-449
- Data Source
  KAKENHI-PROJECT-21591069
[Journal Article] Transthyretin accelerates vascular Abeta deposition in a mouse model of Alzheimer's disease2009
- Author(s)
  Wati H, Kawarabayashi T, Matsubara E, Kasai A, Hirasawa T, Kubota T, Harigaya Y, Shoji M, Maeda S
- Journal Title
  
  Brain Pathol 19(1)
  
  Pages: 48-57
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390233
[Journal Article] Transthyretin accelerates vascular Aβ deposition in a mouse model of Alzheimer's disease2009
- Author(s)
  Wati H, Kawarabayashi T, Matsubara E, Kasai A, Hirasawa T, Kubota T, Harigaya Y, Shoji M, Maeda S
- Journal Title
  
  Brain Pathol
  
  Volume: 19 Pages: 48-57
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591069
[Journal Article] An unusual case of chronic relapsing tetanus associated with mandibular osteomyelitis.2009
- Author(s)
  Wakasaya Y, Watanabe M, Tomiyama M, Suzuki C, Jackson M, Fujimuro M, Kimura T, Seino Y, Kawarabayashi T, Yamamoto-Watanabe Y, Matsubara E, Shirahama I, Takamura A, Nakahata N, Shoji M.
- Journal Title
  
  Intern Med. 48
  
  Pages: 1311-3
- NAID
  130000121961
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390233
[Journal Article] ダッチタイプおよびアイスランドタイプ遺伝性脳出血2009
- Author(s)
  瓦林毅
- Journal Title
  
  神経内科 70
  
  Pages: 172-179
- Data Source
  KAKENHI-PROJECT-19590976
[Journal Article] An unusual case of chronic relapsing tetanus associatec with mandibular osteomyelitis2009
- Author(s)
  Wakasaya Y, Watanabe M, Tomiyama M, Suzuki C, Jackson M, Fujimuro M, Kimura T, Seino Y, Kawarabayashi T, Yamamoto-Watanabe Y, Matsubara E, Shirahama I, Takamura A, Nakahata N, Shoji M
- Journal Title
  
  Intern Med (Epub ahead of print)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590976
[Journal Article] A chemical chaperone, sodium 4-phenylbutyric acid, attenuates the pathogenic potency in human alpha-synuclein A30P+A53T transgenic mice.2009
- Author(s)
  Ono K, Ikemoto M, Kawarabayashi T, Ikeda M, Nishinakagawa T, Hosokawa M, Shoji M, Takahashi M, Nakashima M.
- Journal Title
  
  Parkinsonism Relat Disord. 15
  
  Pages: 649-54
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390233
[Journal Article] An unusual case of chronic relapsing tetanus associated with mandibular osteomyelitis2009
- Author(s)
  Wakasaya Y, Watanabe M, Tomiyama M, Suzuki C, Jackson M, Fujimuro M, Kimura T, Seino Y, Kawarabayashi T, Yamamoto-Watanabe Y, Matsubara E, Shirahama I, Takamura A, Nakahata N, Shoji M
- Journal Title
  
  Intern Med, Epubahead of print
- NAID
  130000121961
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590976
[Journal Article] A chemical chaperone, sodium 4-phenylbutyric acid, attenuates the pathogenic potency in human alpha-synuclein A30P+A53T transgenic mice2009
- Author(s)
  Ono K, Ikemoto M, Kawarabayashi T, Ikeda M, Nishinakagawa T, Hosokawa M, Shoji M, Takahashi M, Nakashima M
- Journal Title
  
  Parkinsonism Relat Disord 15(9)
  
  Pages: 649-54
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390233
[Journal Article] 動物モデルからみた神経変性疾患. 前頭側頭型認知症2008
- Author(s)
  瓦林毅, 東海林幹夫
- Journal Title
  
  神経内科 68
  
  Pages: 119-128
- Data Source
  KAKENHI-PROJECT-19590976
[Journal Article] 多系統萎縮症2008
- Author(s)
  渡辺光法, 木村珠喜, 鈴木千恵子, 瓦林毅, 冨山誠彦, 東海林幹夫
- Journal Title
  
  Modern Physician 28
  
  Pages: 629-633
- Data Source
  KAKENHI-PROJECT-19590976
[Journal Article] Microglial activation in brain lesions with tau deposits : Comparison ot human tauopathies and tau transgenic mice TgTau(P301L).2008
- Author(s)
  Sasaki A, Kawarabayashi T, Murakami T, Matsubara E, Ikeda M, Hagiwara H, Westaway D, George-Hyslop PS, Shoji M, Nakazato Y.
- Journal Title
  
  Brain Res. 1214
  
  Pages: 159-68
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590968
[Journal Article] Alzheimer病-分子標的治療への展望2008
- Author(s)
  渡辺光法, 瓦林毅, 冨山誠彦, 東海林幹夫
- Journal Title
  
  神経治療学 25
  
  Pages: 19-23
- Data Source
  KAKENHI-PROJECT-19590976
[Journal Article] Plasma antibodies to Abeta40 and Abeta42 in patients with Alzheimer's disease and normal controls2008
- Author(s)
  Xu W, Kawarabayashi T, Matsubara E, Deguchi K, Murakami T, Harigaya Y, Ikeda M, Amari M, Kuwano R, Abe K, Shoji M
- Journal Title
  
  Brain Res 1219
  
  Pages: 169-79
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390233
[Journal Article] A small trinucleotide expansion in the TBP gene gives rise to a sporadic case of SCA17 with abnormal putaminal findings on MRI2008
- Author(s)
  Watanabe M, Monai N, Jackson M, Yamamoto-Watanabe Y, Ikeda Y, Suzuki C, Tomiyama M, Kawarabayashi T, Kimura T, Seino Y, Wakasaya Y, Miki Y, Matsubara E, Shoji M
- Journal Title
  
  Intern Med 47(24)
  
  Pages: 2179-82
- NAID
  130000079782
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390233
[Journal Article] 研究成果から予防を考える5. 動物実験から予防を考える2008
- Author(s)
  瓦林毅, 東海林幹夫
- Journal Title
  
  Modern Physician 28
  
  Pages: 1477-1484
- Data Source
  KAKENHI-PROJECT-19590976
[Journal Article] Differentiation of PA from early PSP with different patterns of symptoms and CBF reduction Kamiya T, Shoji M, Abe K2008
- Author(s)
  Kurata T, Hayashi T, Murakami T, Miyazaki K, Morimoto N, Ohta Y, Takehisa Y, Nagai M, Kawarabayashi T, Takao Y, Ohta T, Harigaya Y, Manabe Y
- Journal Title
  
  Neurol Res 30(8)
  
  Pages: 860-7
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390233
[Journal Article] Plasma biomarkers of Alzheimer's disease2008
- Author(s)
  Kawarabayashi T, Shoji M
- Journal Title
  
  Curr Opin Psychiatry 21(3)
  
  Pages: 260-7
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390233
[Journal Article] Microglial activation in brain lesions with tau deposits : comparison of human tauopathies and tau transgenic mice TgTauP301L2008
- Author(s)
  Sasaki A, Kawarabayashi T, Murakami T, Matsubara E, Ikeda M, Hagiwara H, Westaway D, St. George-Hyslop P, Shoji M, Nakazato Y
- Journal Title
  
  Brain Res 1214
  
  Pages: 260-267
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590976
[Journal Article] アルツハイマー病の最近め進歩アルツハイマー病の早期診断法2008
- Author(s)
  瓦林毅, 東海林幹夫
- Journal Title
  
  臨床検査 52
  
  Pages: 281-288
- Data Source
  KAKENHI-PROJECT-19590976
[Journal Article] A Novel Mutation in the Arylsulfatase A Gene Associated with Adult-Onset Metachromatic Leukodystrophy without Clinical Evidence of Neuropathy2008
- Author(s)
  Suzuki C, Watanabe M, Tomiyama M,Sugimoto K, Nanba E, Jackson M, KimuraT, Seino Y, Wakasaya Y, KawarabayashiT, Miki Y, Yamamoto-Watanabe Y, Shoji M
- Journal Title
  
  Eur Neurol 60
  
  Pages: 310-311
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590976
[Journal Article] A Novel Mutation in the Arylsulfatase A Gene Associated with Adult-Onset Metachromatic Leukodystrophy without Clinical Evidence of Neuropathy.2008
- Author(s)
  Suzuki C, Watanabe M, Tomiyama M, Sugimoto K, Nanba E, Jackson M, Kimura T, Seino Y, Wakasaya Y, Kawarabayashi T, Miki Y, Yamamoto-Watanabe Y, Shoji M
- Journal Title
  
  Eur Neurol 60
  
  Pages: 310-311
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590976
[Journal Article] A novel mutation in the arylsulfatase A gene associated with adult-onset metachromatic leukodystrophy without clinical evidence of neuropathy2008
- Author(s)
  Suzuki C, Watanabe M, Tomiyama M, Sugimoto K, Nanba E, Jackson M, Kimura T, Seino Y, Wakasaya Y, Kawarabayashi T, Miki Y, Yamamoto-Watanabe Y, Shoji M
- Journal Title
  
  Eur Neurol 60(6)
  
  Pages: 310-1
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390233
[Journal Article] Plasma biomarkers of Alzheimer's disease.2008
- Author(s)
  Kawarabayashi T, Shoji M
- Journal Title
  
  Curr Opin Psychiatry 21
  
  Pages: 260-267
- Data Source
  KAKENHI-PROJECT-19590976
[Journal Article] 脂質管理による認知症の予防2008
- Author(s)
  瓦林毅, 東海林幹夫
- Journal Title
  
  分子脳血管病 7
  
  Pages: 66-71
- Data Source
  KAKENHI-PROJECT-19590976
[Journal Article] Microglial activation in brain lesions with tau deposits : comparison of human tauopathies and tau transgenic mice TgTauP301L2008
- Author(s)
  Sasaki A, Kawarabayashi T, Murakami T, Matsubara E, Ikeda M, Hagiwara H, Westaway D, George-Hyslop PS, Shoji M, Nakazato Y
- Journal Title
  
  Brain Res. 1214
  
  Pages: 159-68
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390233
[Journal Article] アルツハイマー病3診断と治療のためのバイオマーカー2008
- Author(s)
  渡辺光法, 瓦林毅, 冨山誠彦, 東海林幹夫
- Journal Title
  
  治療学 42
  
  Pages: 53-56
- Data Source
  KAKENHI-PROJECT-19590976
[Journal Article] Reuptake of L-DOPA-derived extracellular DA in the striatum of a rodent model of Parkinson's disease via norepinephrine transporter2008
- Author(s)
  Arai A, Tomiyama M, Kannari K, Kimura T, Suzuki C, Watanabe M, Kawarabayashi T, Shen H, Shoji M
- Journal Title
  
  Synapse 62(8)
  
  Pages: 632-5
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390233
[Journal Article] Reuptake of L-DOPA-derived extracellular DA in the striatum of a rodent model of Parkinson's disease via norepinephrine -transporter2008
- Author(s)
  Arai A, Tomiyama M, Kannari K, Kimura T, Suzuki C, Watanabe M, Kawarabayashi T, Shen H, Shoji M
- Journal Title
  
  Synapse 62
  
  Pages: 632-635
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590976
[Journal Article] アルツハイマー病のバイオマーカー2008
- Author(s)
  渡辺光法, 瓦林毅, 冨山誠彦, 東海林幹夫
- Journal Title
  
  カレントテラピー 26
  
  Pages: 45-49
- Data Source
  KAKENHI-PROJECT-19590976
[Journal Article] Plasma antibodies to Abeta40 and Abeta42 in patients with Alzheimer's disease and normal controls2008
- Author(s)
  Xu W, Kawarabayashi T, Matsubara E, Deguchi K, Murakami T, Harigaya Y, Ikeda M, Amari M, Kuwano R, Abe K, Shoji M
- Journal Title
  
  Brain Res. 1219
  
  Pages: 169-79
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390233
[Journal Article] A small trinucleotide expansion in the TBP gene gives rise to a sporadic case of SCA17 with abnormal putaminal findings on MRI2008
- Author(s)
  Watanabe M, Monai N, Jackson M, Yamamoto-Watanabe Y, Ikeda Y, Suzuki C, Tomiyama M, Kawarabayashi T, Kimura T, Seino Y, Wakasaya Y, Miki Y, Matsubara E, Shoji M
- Journal Title
  
  Intern Med 47
  
  Pages: 2179-2182
- NAID
  130000079782
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590976
[Journal Article] Plasma antibodies to AB40 and AB42 in patients with Alzheimer's disease and normal controls2008
- Author(s)
  Xu W, Kawarabayashi T, Matsubara E, Deguchi K, Murakami T, Harigaya Y, Ikeda M, Amari M, Kuwano R, Abe K, Shoji M
- Journal Title
  
  Brain Res 1219
  
  Pages: 169-179
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590976
[Journal Article] Plasma biomarkers of Alzheimer's disease2008
- Author(s)
  Kawarabayashi T, Shoji M
- Journal Title
  
  Curr Opin Psychiatry 21
  
  Pages: 260-267
- Data Source
  KAKENHI-PROJECT-19590976
[Journal Article] Differentiation of PA from early PSP with different patterns of symptoms and CBF reduction2008
- Author(s)
  Kurata T, Hayashi T, Murakami T, Miyazaki K, Morimoto N, Ohta Y, Takehisa Y, Nagai M, Kawarabayashi T, Takao Y, Ohta T, Harigaya Y, Manabe Y, Kamiya T, Shoji M, Abe K
- Journal Title
  
  Neurol Res 30
  
  Pages: 860-867
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590976
[Journal Article] Differentiation of PA from early PSP with different patterns of symptoms and CBF reduction2008
- Author(s)
  Kurata T, Hayashi T, Murakami T, Miyazaki K, Morimoto N, Ohta Y, Takehisa Y, Nagai M, Kawarabayashi T, Takao Y, Ohta T, Harigaya Y, Manabe Y, Kamiya T, Shoji M, Abe K.
- Journal Title
  
  Neurol Res 30
  
  Pages: 860-867
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590976
[Journal Article] Plasma antibodies to Abeta40 and Abeta42 in patients with Alzheimer's disease and normal controls.2008
- Author(s)
  Xu W, Kawarabayashi T, Matsubara E, Deguchi K, Murakami T, Harigaya Y, Ikeda M, Amari M, Kuwano R, Abe K, Shoji M.
- Journal Title
  
  Brain Res (Epub ahead of print)
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590968
[Journal Article] Exacerbation of chronic pancreatitis induced by anticholinesterase medications in myasthenia gravis.2008
- Author(s)
  Murakami T, Moriwaki Y, Kawarabayashi T, Nagai M, Ohta Y, Deguchi K, Kurata T, Takehisa Y, Matsubara E, Ikeda M, Harigaya Y, Shoji M, Takahashi R, Abe K
- Journal Title
  
  Eur J Neurol 15
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590976
[Journal Article] Microglial activation in brain lesions with tau deposits : comparison of human tauopathies and tau transgenic mice TgTauP301L2008
- Author(s)
  Sasaki A, Kawarabayashi T, Murakami T, Matsubara E, Ikeda M, Hagiwara H, Westaway D, George-HyslOp PS, Shoji M, Nakazato Y
- Journal Title
  
  Brain Res 1214
  
  Pages: 159-68
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390233
[Journal Article] アルツハイマー病の新規バイオマーカーの開発2008
- Author(s)
  渡辺光法, 瓦林毅, 冨山誠彦, 東海林幹夫
- Journal Title
  
  BIO Clinica 23
  
  Pages: 47-51
- Data Source
  KAKENHI-PROJECT-19590976
[Journal Article] 認知症のバイオマーカー2008
- Author(s)
  渡辺光法, 瓦林毅, 冨山誠彦, 東海林幹夫
- Journal Title
  
  臨床と研究 85
  
  Pages: 489-492
- Data Source
  KAKENHI-PROJECT-19590976
[Journal Article] Differentiation of PA from early PSP with different patterns of symptoms and CBF reduction2008
- Author(s)
  Kurata T, Hayashi T, Murakami T, Miyazaki K, Morimoto N, Ohta Y, Takehisa Y, Nagai M, Kawarabayashi T, Takao Y, Ohta T, Harigaya Y, Manabe Y, Kamiya T, Shoji M, Abe K
- Journal Title
  
  Neurol Res. 30(8)
  
  Pages: 860-7
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390233
[Journal Article] Transthyretin Accelerates Vascular Abeta Deposition in a Mouse Model ol Alzheimer's Disease.2008
- Author(s)
  Wati H, Kawarabayashi T, Matsubara E, Kasai A, Hirasawa T, Kubota T, Harigaya Y, Shoji M, Maeda S.
- Journal Title
  
  Brain Pathol 2008 Apr 22 (Epub ahead of print)
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590968
[Journal Article] Exacerbation of chronic pancreatitis induced by anticholinesterase medications in myasthenia gravis2008
- Author(s)
  Tomiyama M, Arai A, Kimura T, Suzuki C, Watanabe M, Kawarabayashi T, Shoji M
- Journal Title
  
  Eur J Neurol 15
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590976
[Journal Article] A small trinucleotide expansion in the TBP gene gives rise to asporadic case of SCA17 with abnormal putaminal findings on MRI2008
- Author(s)
  Watanabe M, Monai N, Jackson M, Yamamoto-Watanabe Y, Ikeda Y, Suzuki C, Tomiyama M, Kawarabayashi T, Kimura T, Seino Y, Wakasaya Y, Miki Y, Matsubara E, Shoji M
- Journal Title
  
  Intern Med 47
  
  Pages: 2179-2182
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590976
[Journal Article] Reuptake of L-DOPA-derived extracellular DA in the striatum of a rodent model of Parkinson's disease via norepinephrine transporter2008
- Author(s)
  Arai A, Tomiyama M, Kannari K, Kimura T, Suzuki C, Watanabe M, Kawarabayashi T, Shen H, Shoji M
- Journal Title
  
  Synapse 62
  
  Pages: 632-635
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590976
[Journal Article] Plasma antibodies to Abeta40 and Abeta42 in patients with Alzheimer's disease and normal controls2008
- Author(s)
  Xu W, Kawarabayashi T, Matsubara E, Deguchi K, Murakami T, Harigaya Y, Ikeda M, Amari M, Kuwano R, Abe K, Shoji M
- Journal Title
  
  Brain Res 121
  
  Pages: 169-179
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590976
[Journal Article] Enhanced accumulation of phosphorylated alpha-synuclein in double transgenic mice expressing mutant beta-amyloid precursor protein and presenilin-12007
- Author(s)
  Kurata T, Kawarabayashi T, Murakami T, Miyazaki K, Morimoto N, Ohta Y, Takehisa Y, Nagai M, Ikeda M, Matsubara E, Westaway D, Hyslop PS, Harigaya Y, Kamiya T, Shoji M, Abe K
- Journal Title
  
  J Neurosci Res. 85(10)
  
  Pages: 2246-52
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390233
[Journal Article] PINK1, a gene product of PARK6, accumulates in □-synucleinopathy brains.2007
- Author(s)
  Murakami T, Moriwaki Y, Kawarabayashi T, Nagai M, Ohta Y, Deguchi K, Kurata T, Takehisa Y, Matsubara E, Ikeda M, Harigaya Y, Shoji M, Takahashi R, Abe
- Journal Title
  
  J Neurol Neurosurg Psychiatry. 8
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17590879
[Journal Article] Enhanced accumulation of phosphorylated alpha-synuclein double transgenic mice expressing mutant beta-amyloid precursor protein and presenilin-1.2007
- Author(s)
  Kurata T, Kawarabayashi T, Murakami T, Miyazaki K, Morimoto N, Ohta Y, Takehisa Y, Nagai M, Ikeda M, Matsubara E, Westaway D, Hyslop PS, Harigaya Y, Kamiya T, Shoji M, Abe K.
- Journal Title
  
  J Neurosci Res. 85(10)
  
  Pages: 2246-52
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590968
[Journal Article] PINK1, a gene product of PARK6, accumulates in α-synucleinopathy brains2007
- Author(s)
  Murakami T, Moriwaki Y, Kawarabayashi T, Nagai M, Ohta Y, Deguchi K, Kurata T, Takehisa Y, Matsubara E, Ikeda M, Harigaya Y, Shoji M, Takahashi R, Abe K
- Journal Title
  
  J Neurol Neurosurg Psychiatry 78(6)
  
  Pages: 653-4
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390233
[Journal Article] Enhanced accumulation of phosphorylated alpha-synuclein in double transgenic mice expressing mutant beta-amyloid precursor protein and presenilin-12007
- Author(s)
  Kurata T, Kawarabayashi T, Murakami T, Miyazaki K, Morimoto N, Ohta Y, Takehisa Y, Nagai M, Ikeda M, Matsubara E, Westaway D, Hyslop PS, Harigaya Y, Kamiya T, Shoji M, Abe K
- Journal Title
  
  J Neurosci Res 85
  
  Pages: 22462252-22462252
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390233
[Journal Article] PINK1, a gene product of PARK6, accumulates in {alpha}-synucleinopathy brains.2007
- Author(s)
  Murakami T, Moriwaki Y, Kawarabayashi T, Nagai M, Ohta Y, Deguchi K, Kurata T, Takehisa Y, Matsubara E, Ikeda M, Harigaya Y, Shoji M, Takahashi R, Abe K.
- Journal Title
  
  J Neurol Neurosurg Psychiatry. 78(6)
  
  Pages: 653-4
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590968
[Journal Article] PINK1, a gene product of PARK6, accumulates in □-synucleinopathy brains.2007
- Author(s)
  Murakami T, Moriwaki Y, Kawarabayashi T, Nagai M, Ohta Y, Deguchi K, Kurata T, Takehisa Y, Matsubara E, Ikeda M, Harigaya Y, Shoji M, Takahashi R, Abe
- Journal Title
  
  J Neurol Neurosurg Psychiatry. 8 (Epub ahead of prin)
- Data Source
  KAKENHI-PROJECT-17590879
[Journal Article] a gene product of PARK6, accumulates in α-synucleinopathy brains2007
- Author(s)
  Murakami T, Moriwaki Y, Kawarabayashi T, Nagai M, Ohta Y, Deguchi K, KurataT, Takehisa Y, Matsubara E, Ikeda M, Harigaya Y, Shoji M, Takahashi R, Abe K, PINK1
- Journal Title
  
  J Neurol Neurosurg Psychiatry 78
  
  Pages: 653-654
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590976
[Journal Article] PINK1, a gene product of PARK6, accumulates in α-synucleinopathy brains.2007
- Author(s)
  Murakami T, Moriwaki Y, Kawarabayashi T, Nagai M, Ohta Y, Deguchi K, Kurata T, Takehisa Y, Matsubara E, Ikeda M, Harigaya Y, Shoji M, Takahashi R, Abe K
- Journal Title
  
  J Neurol Neurosurg Psychiatry 78
  
  Pages: 653-654
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590976
[Journal Article] PINK1, a gene product of PARK6, accumulates in □-synucleinopathy brains.2007
- Author(s)
  Murakami T, Moriwaki Y, Kawarabayashi T, Nagai M, Ohta, Y, Deguchi K, Kurata T, Takehisa Y, Matsubara E, Ikeda M, Harigaya Y, Shoji M, Takahashi R, Abe
- Journal Title
  
  J Neurol Neurosurg Psychiatry. 8(Epub ahead of prin)
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17590879
[Journal Article] Enhanced accumulation of phosphorylated α-synuclein in double transgenic mice expressing mutant βAPP and presenilin-1.2007
- Author(s)
  Kurata T, Kawarabayashi T, Murakami T, Miyazaki K, Morimoto N, Ohta Y, Takehisa Y, Nagai M, Ikeda M, Matsubara E, Westaway D, St. George-Hyslop P, Harigaya Y, Kamiya T, Shoji M, Abe K
- Journal Title
  
  J Neurosci Res 85
  
  Pages: 2246-2252
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590976
[Journal Article] PINK1, a gene product of PARK6, accumulates in {alpha}-synucleinopathy brains2007
- Author(s)
  Murakami T, Moriwaki Y, Kawarabayashi T, Nagai M, Ohta Y, Deguchi K, Kurata T, Takehisa Y, Matsubara E, Ikeda M, Harigaya Y, Shoji M, Takahashi R, Abe K
- Journal Title
  
  J Neurol Neurosurg Psychiatry 78
  
  Pages: 653-654
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390233
[Journal Article] トランスジェニックマウスを用いたアルツハイマー病発症機序の解析2007
- Author(s)
  瓦林毅, 針谷康夫, 池田将樹, 岡本幸市, 東海林幹夫, 松原悦朗.
- Journal Title
  
  老年期痴呆研究会誌 14
  
  Pages: 9-11
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590968
[Journal Article] Enhanced accumulation of phosphorylated α-synuclein in double transgenic mice expressing mutant βAPP and presenilin-12007
- Author(s)
  Kurata T, Kawarabayashi T, Murakami T, Miyazaki K, Morimoto N, Ohta Y, Takehisa Y, Nagai M, Ikeda M, Matsubara E, Westaway D, St.George-Hyslop P, Harigaya Y, Kamiya T, Shoji M, Abe K
- Journal Title
  
  J Neurosci Res 85
  
  Pages: 2246-2252
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590976
[Journal Article] Enhanced accumulation of tau in double transgenic mice expressing mutant beta APP and presenilin-1.2006
- Author(s)
  Samura E, Shoji M, Kawarabayashi T, Sasaki A, Matsubara E, Murakami T, Wuhua X, Tamura S, Ikeda M, Ishiguro K, Saido TC, Westaway D, St George Hyslop P, Harigaya Y, Abe K
- Journal Title
  
  Brain Res 1094(1)
  
  Pages: 192-199
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590968
[Journal Article] Type-specific evolution of amyloid plaque and angiopathy in APPsw mice.2006
- Author(s)
  Harigaya Y, Tomidokoro Y, Ikeda M, Sasaki A, Kawarabayashi T, Matsubara E, Kanai M, Saido TC, Younkin SG, Shoji M.
- Journal Title
  
  Neurosci Lett 395(1)
  
  Pages: 37-41
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590968
[Journal Article] Cortical neuronal and glial pathology in TgTauP301L transgenic mice : neuronal degeneration, memory disturbance, and phenotypic variation.2006
- Author(s)
  Murakami T, Paitel E, Kawarabayashi T, Ikeda M, Chishti MA, Janus C, Matsubara E, Sasaki A, Kawarai T, Phinney AL, Harigaya Y, Home P, Egashira N, Mishima K, Hanna A, Yang J, Iwasaki K, Takahashi M, Fujiwara M, Ishiguro K, Bergeron C, Carlson GA, Abe K, Westaway D, St George-Hyslop P, Shoji M
- Journal Title
  
  Am J Pathol 169(4)
  
  Pages: 1365-1375
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590968
[Journal Article] Dimeric Aβ Rapidly Accumulates in Lipid Rafts Followed by ApoE and Phosphorylated Tau as Memory is Impaired in the Tg2576 Mouse Model of Alzheimer's Disease.2004
- Author(s)
  Kawarabayashi T, Shoji M, et al.
- Journal Title
  
  J Neurosci 24
  
  Pages: 3801-3809
- Data Source
  KAKENHI-PROJECT-16390251
[Journal Article] Microglial activation in brain lesions with tau deposits: comparison of human tauopathies and tau transgenic mice TgTauP301L.
- Author(s)
  Sasaki A, Kawarabayashi T, Murakami T, Matsubara E, Ikeda M, Hagiwara H, Westaway D, St. George-Hyslop P, Shoji M, Nakazato Y
- Journal Title
  
  Brain Res in press
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590976
[Journal Article] Transthyretin accelerates vascular Aβ deposition in a mouse model of Alzheimer's disease.
- Author(s)
  Wati H, Kawarabayashi T, Matsubara E, Kasai A, Hirasawa T, Kubota T, Harigaya Y, Shoji M, Maeda S
- Journal Title
  
  Brain Pathol in press
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590976
[Patent] ワクチンを蓄積する形質転換ダイズ植物およびその利用2008
- Inventor(s)
  寺川輝彦, 長谷川久和, 石本政男, 内海成, 東海林幹夫, 瓦林毅
- Industrial Property Rights Holder
  北興化学工業株式会社, 独立行政法人農業・食品産業技術総合研究機構, 国立大学法人京都大学, 国立大学法人弘前大学
- Industrial Property Number
  2008-304006
- Filing Date
  2008-11-28
- Data Source
  KAKENHI-PROJECT-19590976
[Patent] ワクチンを蓄積する形質転換ダイズ植物およびその利用2008
- Inventor(s)
  東海林幹夫, 瓦林毅
- Industrial Property Rights Holder
  弘前大学, 京都大学, 北興化学
- Industrial Property Number
  2008-301006
- Filing Date
  2008-11-28
- Data Source
  KAKENHI-PROJECT-19390233
[Presentation] Age-related cognitive decline and prevalence of MCI in the Iwaki Health Promotion Project2023
- Author(s)
  Takeshi Kawarabayashi, Naoko Nakahata, Takumi Nakamura, Masamitsu Takatama, Mikio Shoji
- Organizer
  AAIC2023 ALZHEIMER’S ASSOCIATION INTERNATIONAL CONFERENCE
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K07511
[Presentation] 血漿中ApoE4は，ApoE2およびApoE3より低値である2023
- Author(s)
  中村琢洋，瓦林毅，柴田真，笠原浩生，牧岡幸樹，池田佳生，東海林幹夫
- Organizer
  第64回日本神経学会学術集会
- Data Source
  KAKENHI-PROJECT-22K07511
[Presentation] リピドラフトはアミロイドβ蛋白蓄積による神経障害の共通したプラットフォームである2022
- Author(s)
  瓦林毅，東海林幹夫、甘利雅邦、菅原隆、岩崎理、岡大典，高玉真光
- Organizer
  令和4年度秋季群馬県医学会
- Data Source
  KAKENHI-PROJECT-22K07511
[Presentation] バイオマーカーとしての脳脊髄液血液神経細線維軽鎖の意議2022
- Author(s)
  東海林幹夫，瓦林毅，甘利雅邦，菅原隆，岡大典，石澤邦彦，高玉真光
- Organizer
  令和4年度秋季群馬県医学会
- Data Source
  KAKENHI-PROJECT-22K07511
[Presentation] Lipid rafts act as a common platform for Aβ oligomer-induced Alzheimer’s pathology2022
- Author(s)
  Takeshi Kawarabayashi, Takumi Nakamura, Masamitsu Takatama, Mikio Shoji
- Organizer
  AAIC2022 ALZHEIMER’S ASSOCIATION INTERNATIONAL CONFERENCE
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K07511
[Presentation] Alzheimer病の病態カスケードはlipid raftを共通のプラットフォームとして進行する2022
- Author(s)
  瓦林毅、中村琢洋、高玉真光、東海林幹夫
- Organizer
  第41回日本認知症学会学術集会
- Data Source
  KAKENHI-PROJECT-22K07511
[Presentation] Lipid rafts act as a common platform for Aβ oligomer-induced Alzheimer’s pathology2022
- Author(s)
  Takeshi Kawarabayashi, Takumi Nakamura, Kaoru Sato, Yusuke Seino, Sadanobu Ichii, Naoko Nakahata, Masamitsu Takatama, Mikio Shoj
- Organizer
  第63回日本神経学会学術集会
- Data Source
  KAKENHI-PROJECT-22K07511
[Presentation] Quantitative measurement of CSF Abeta species by mass spectrometr2021
- Author(s)
  Takeshi Kawarabayashi， Yusuke Seino， Takumi Nakamura， Tomoo Harada， Naoko Nakahata，Tetsuya Ueda，Masamitsu Takatama， Mikio Shoji
- Organizer
  Alzheimer’s Association International Conference (AAIC) 2021
- Data Source
  KAKENHI-PROJECT-19K07989
[Presentation] 質量分析法によるアミロイドbeta蛋白定量法の開発2021
- Author(s)
  瓦林毅，東海林幹夫、甘利雅邦、菅原隆、岩崎理、岡大典，高玉真光
- Organizer
  令和3年秋季群馬県医学会
- Data Source
  KAKENHI-PROJECT-19K07989
[Presentation] Quantitative measurement of CSF Abeta species by mass spectrometry2021
- Author(s)
  Takeshi Kawarabayashi， Yusuke Seino， Takumi Nakamura， Tomoo Harada， Naoko Nakahata，Tetsuya Ueda，Masamitsu Takatama， Mikio Shoji
- Organizer
  第62回日本神経学会学術集会
- Data Source
  KAKENHI-PROJECT-19K07989
[Presentation] Mass spectrometryによるAbetaの定量2021
- Author(s)
  瓦林毅，清野祐輔，中村琢洋, 原田朋夫，中畑直子，上田哲也，高玉真光，東海林幹夫
- Organizer
  第41回日本認知症学会学術集
- Data Source
  KAKENHI-PROJECT-19K07989
[Presentation] Cerebrospinal fluid and plasma biomarkers in neurodegenerative diseases.2020
- Author(s)
  Kawarabayashi T， Seino Y， Nakamura T， Takatama M， Shoji M
- Organizer
  61st annual meeting of Japanese society of Neurology
- Data Source
  KAKENHI-PROJECT-19K07989
[Presentation] Oral immunization with soybean storage protein containing amyloid β4-10 prevents spatial learning decline2020
- Author(s)
  Kawarabayashi T, Nakamura T, Takatama M, Shoji M
- Organizer
  Alzheimer’s Association International Conference (AAIC) 2020
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K07989
[Presentation] 神経変性疾患の脳脊髄液および血液バイオマーカーの検討．2020
- Author(s)
  瓦林毅，高玉真光，東海林幹夫
- Organizer
  令和2年度秋季群馬県医学会
- Data Source
  KAKENHI-PROJECT-19K07989
[Presentation] 神経変性疾患の血漿・脳脊髄液バイオマーカー解析と新規タウELISAの開発．2020
- Author(s)
  瓦林毅，高玉真光，東海林幹夫
- Organizer
  第39回日本認知症学会学術集会
- Data Source
  KAKENHI-PROJECT-19K07989
[Presentation] 血漿Abeta値は腎機能により強い影響を受け，MMSEと相関する：岩木プロジェクト2019
- Author(s)
  中村琢洋、瓦林毅，清野祐輔，笠原浩生，池田将樹，池田佳生，東海林幹夫
- Organizer
  第10回日本脳血管・認知症学会総会
- Data Source
  KAKENHI-PROJECT-19K07989
[Presentation] Oral immunization with soybean storage protein containing Abeta4-102019
- Author(s)
  Kawarabayashi T, Amari M, Takatama M, Shoji M
- Organizer
  Neuroscience 2019, the Society for Neuroscience, 49th Annual Meeting
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K07989
[Presentation] Oral immunization with soybean storage protein containing Abeta4-10 in Alzheimer's model mice2019
- Author(s)
  Takeshi Kawarabayashi， Takumi Nakamura， Yusuke Seino， Mie Hirohata， Mikio Shoji
- Organizer
  第60回日本神経学会学術大会
- Data Source
  KAKENHI-PROJECT-19K07989
[Presentation] 組み換えダイズ蛋白によるアルツハイマー病発症予防療法の開発2019
- Author(s)
  瓦林毅, 中村巧洋, 甘利雅邦, 高玉真光, 東海林幹夫
- Organizer
  第10回日本脳血管・認知症学会総会
- Data Source
  KAKENHI-PROJECT-19K07989
[Presentation] 組み替え大豆蛋白によるアルツハイマー病経口免疫の作用機序の検討2019
- Author(s)
  瓦林毅，中村琢洋，清野祐輔，亀谷富由樹、池田佳生、高玉真光、東海林幹夫
- Organizer
  第38回日本認知症学会学術集会
- Data Source
  KAKENHI-PROJECT-19K07989
[Presentation] Abeta oligomers in synaptic lipid rafts induce phosphorylated tau and impair signal transduction.2017
- Author(s)
  Takeshi Kawarabayashi, Sakiko Narita, Kaoru Sato, Takumi, Nakamura, Mie Hirohata, Naoko Nakahata, and Mikio Shoji
- Organizer
  Neuroscience 2017, the Society for Neuroscience, 47th Annual Meeting
- Data Source
  KAKENHI-PROJECT-15K09305
[Presentation] Cerebrospinal fluid and blood biomarkers in neurological diseases2017
- Author(s)
  Yusuke Seino, Sakiko Narita, Takumi Nakamura, Mie Hirohata, Takeshi Kawarabayashi, Mikio Shoji
- Organizer
  DIAN Family Conference
- Data Source
  KAKENHI-PROJECT-15K09305
[Presentation] Abeta oligomerはシナプスのlipid raftsでtauを誘発する2017
- Author(s)
  瓦林毅，成田早希子，佐藤薫，中村琢洋，廣畑美枝，清野祐輔，中畑直子，東海林幹夫
- Organizer
  第36回日本認知症学会学術集会
- Data Source
  KAKENHI-PROJECT-15K09305
[Presentation] Abeta oligomers in synaptic lipid rafts induce phosphorylated tau and impair signal transduction2017
- Author(s)
  Takeshi Kawarabayashi, Sakiko Narita, Kaoru Sato, Takumi, Nakamura, Mie Hirohata, Naoko Nakahata, and Mikio Shoji
- Organizer
  Neuroscience 2017, the Society for Neuroscience, 47th Annual Meeting, Washington D.C, Nov 11-15
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K09306
[Presentation] Induction of Phosphorylated Tau and Fyn-NMDA Receptor Transduction Pathway by Aß Oligomers in Synapse2017
- Author(s)
  Takeshi Kawarabayashi, Takumi Nakamura, Mie Hirohata, Yusuke Seino, and Mikio Shoji
- Organizer
  XXIII World Congress of Neurology
- Data Source
  KAKENHI-PROJECT-15K09305
[Presentation] Cerebrospinal fluid and blood biomarkers in neurological diseases.2017
- Author(s)
  Yusuke Seino, Takumi Nakamura, Mie Hirohata, Takeshi Kawarabayashi, Mikio Shoji
- Organizer
  XXIII World Congress of Neurology
- Data Source
  KAKENHI-PROJECT-15K09305
[Presentation] Cerebrospinal fluid and blood biomarkers in neurological diseases2017
- Author(s)
  Yusuke Seino, Takumi Nakamura, Mie Hirohata, Takeshi Kawarabayashi, Mikio Shoji
- Organizer
  ⅩⅩⅢ World Congress of Neurology, Kyoto, Sep 16-21
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K09306
[Presentation] DIAN-Japan HUGSM 710 site, Hirosaki, Japan,2017
- Author(s)
  Mikio Shoji, Naoko Nakahata, Tomoyo Shirato, Sakiko Narita, Takumi Nakamura, Seino Yusuke, Mie Hirohata, Takeshi Kawarabayashi
- Organizer
  2017 DIAD Family Conference, London, July 15
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K09306
[Presentation] Induction of Phosphorylated Tau and Fyn-NMDA Receptor Transduction Pathway by Abuta Oligomers in Synapse2017
- Author(s)
  Takeshi Kawarabayashi, Takumi Nakamura, Mie Hirohata, Yusuke Seino, and Mikio Shoji
- Organizer
  XXIII World Congress of Neurology, Kyoto, Sep 16-21
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K09306
[Presentation] 血漿アミロイドbetaの影響因子の解析．2016
- Author(s)
  中村琢洋，瓦林毅，若佐谷保仁，中畑直子，東海林幹夫，高橋一平，中路重之
- Organizer
  第35回日本認知症学会学術集会
- Place of Presentation
  東京国際フォーラム（東京都・千代田区）
- Year and Date
  2016-12-01
- Data Source
  KAKENHI-PROJECT-15K09305
[Presentation] Plasma amyloid beta levels are correlated with cognitive and motor functions.2016
- Author(s)
  Takumi Nakamura, Takeshi Kawarabayashi, Yasuhito Wakasaya, Mikio Shoji
- Organizer
  第57回日本神経学会学術大会
- Place of Presentation
  神戸国際会議場（兵庫県・神戸市）
- Year and Date
  2016-05-18
- Data Source
  KAKENHI-PROJECT-15K09305
[Presentation] Plasma Aβ levels are correlated with cognitive and motor functions in Iwaki Health Promotion Project2016
- Author(s)
  Takumi Nakamura, Takeshi Kawarabayashi, Yasuhito Wakasaya, Naoko Nakahata, Sakiko Narita, Mikio Shoji, Ippei Takahashi, Shigeyuki Nakaji
- Organizer
  68th Annual Meeting of American Academy of Neurology
- Place of Presentation
  バンクーバー（カナダ）
- Year and Date
  2016-04-15
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K09306
[Presentation] Induction of phosphorylated tau in synapse by accumulation of Abeta oligomers.2016
- Author(s)
  Takeshi Kawarabayashi, Takumi Nakamura, Yasuhito Wakasaya, Mikio Shoji
- Organizer
  第57回日本神経学会学術大会
- Place of Presentation
  神戸国際会議場（兵庫県・神戸市）
- Year and Date
  2016-05-18
- Data Source
  KAKENHI-PROJECT-15K09305
[Presentation] Abeta oligomerによるシナプス障害の解析．2016
- Author(s)
  瓦林毅，成田早希子，中村琢洋，若佐谷保仁，中畑直子，東海林幹夫
- Organizer
  第35回日本認知症学会学術集会
- Place of Presentation
  東京国際フォーラム（東京都・千代田区）
- Year and Date
  2016-12-01
- Data Source
  KAKENHI-PROJECT-15K09305
[Presentation] Early induction of phosphorylated tau in synapse from APP transgenic mice.2016
- Author(s)
  Takeshi Kawarabayashi, Sakiko Narita, Takumi Nakamura, Yasuhito Wakasaya, Naoko Nakahata, Mikio Shoji
- Organizer
  Neuroscience 2016, the Society for Neuroscience, 46th Annual Meeting
- Place of Presentation
  San Diego　（アメリカ合衆国）
- Year and Date
  2016-06-12
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K09305
[Presentation] 地域におけるMCI診断の試みアンケート結果の検討2016
- Author(s)
  中畑直子,成田早希子,中村琢洋,若佐谷保仁, 瓦林毅, 東海林幹夫，高橋一平,中路重之
- Organizer
  第35回日本認知症学会学術集会
- Place of Presentation
  東京国際フォーラム（東京都・千代田区）
- Year and Date
  2016-12-01
- Data Source
  KAKENHI-PROJECT-15K09305
[Presentation] CSF and plasma biomarkers for diagnosing dementia in outpatient clinic.2016
- Author(s)
  Masayuki Orikasa, Takeshi Kawarabayashi, Yasuhito Wakasaya, Takumi Nakamura, Naoko Nakahata, Mikio Shoji
- Organizer
  Alzheimer’s Association International Conference, AAIC 2016
- Place of Presentation
  Tronto（カナダ）
- Year and Date
  2016-07-24
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K09305
[Presentation] 脳アミロイドアンギオパチーのマウスモデルを用いた検討．2016
- Author(s)
  成田早希子，瓦林毅，中村琢洋，若佐谷保仁，中畑直子，東海林幹夫
- Organizer
  第35回日本認知症学会学術集会
- Place of Presentation
  東京国際フォーラム（東京都・千代田区）
- Year and Date
  2016-12-01
- Data Source
  KAKENHI-PROJECT-15K09305
[Presentation] Plasma Abeta levels are correlated with cognitive and motor functions in Iwaki Health Promotion Project.2016
- Author(s)
  Takumi Nakamura, Takeshi Kawarabayashi, Yasuhito Wakasaya, Naoko Nakahata, Sakiko Narita, Mikio Shoji, Ippei Takahashi, Shigeyuki Nakaji
- Organizer
  68th Annual Meeting of American Academy of Neurology
- Place of Presentation
  Vancouver（カナダ）
- Year and Date
  2016-04-15
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K09305
[Presentation] Induction of phosphorylated tau in synapse from AD model mice.2015
- Author(s)
  Takeshi Kawarabayashi, Yasuhito Wakasaya, Takumi Nakamura, Naoko Nakahata, Mikio Shoji
- Organizer
  Neuroscience 2015, the Society for Neuroscience, 45th Annual Meeting
- Place of Presentation
  United States of America, Chicago
- Year and Date
  2015-11-17
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K09305
[Presentation] Abeta oligomers: appearance, accumulation, memory disturbance and therapy2015
- Author(s)
  Takeshi Kawarabayashi
- Organizer
  第56回日本神経学会学術大会
- Place of Presentation
  朱鷺メッセ新潟（新潟県・新潟市）
- Year and Date
  2015-05-20
- Invited
- Data Source
  KAKENHI-PROJECT-15K09305
[Presentation] マウスモデルを用いたAbeta oligomer毒性の検討．2015
- Author(s)
  瓦林毅
- Organizer
  第34回日本認知症学会学術集会
- Place of Presentation
  リンクステーションホール青森（青森県・青森市）
- Year and Date
  2015-10-02
- Invited
- Data Source
  KAKENHI-PROJECT-15K09305
[Presentation] Abeta oligomerの神経毒性の検討．2015
- Author(s)
  瓦林毅，中村琢洋，仲田崇，若佐谷保仁，中畑直子，東海林幹夫
- Organizer
  第34回日本認知症学会学術集会
- Place of Presentation
  リンクステーションホール青森（青森県・青森市）
- Year and Date
  2015-10-02
- Data Source
  KAKENHI-PROJECT-15K09305
[Presentation] 吃逆にて発症したNMO spectrum disorderの3例。2014
- Author(s)
  若佐谷保仁，仲田祟，瓦林毅，東海林幹夫、高橋利幸、松原悦朗
- Organizer
  第93回日本神経学会東北地方会
- Place of Presentation
  フォレスト仙台
- Data Source
  KAKENHI-PROJECT-24591246
[Presentation] 経口Aβワクチン療法によるアルツハイマー病治療法の開発．2014
- Author(s)
  瓦林毅
- Organizer
  本神経学会九州地方会
- Place of Presentation
  大分大学
- Year and Date
  2014-09-20
- Invited
- Data Source
  KAKENHI-PROJECT-24591246
[Presentation] 経口Aβワクチンによるアルツハイマー病治療法の開発2013
- Author(s)
  瓦林毅，仲田祟，若佐谷保仁，大野英人，中畑直子，松原悦朗，東海林幹夫
- Organizer
  VSA-COG Japan 2013　第4回日本血管性認知障害研究会
- Place of Presentation
  東京コンファレンスセンター
- Data Source
  KAKENHI-PROJECT-24591246
[Presentation] Accumulation of Aβ oligomers and prion and impaied signal transduction in lipid rafts.2013
- Author(s)
  Kawarabayashi T, Nakata T, Wakasaya Y, Nakahata N, Oono H, Matsubara E, Shoji M
- Organizer
  Neuroscience 2013, the Society for Neuroscience, 43th Annual Meeting
- Place of Presentation
  San Diego Convention Center (USA)
- Data Source
  KAKENHI-PROJECT-24591246
[Presentation] もの忘れ外来における認知症リハビリテーションの現状と効果2013
- Author(s)
  仲田崇, 瓦林毅, 若佐谷保仁, 中畑直子, 松原悦朗, 東海林幹夫
- Organizer
  第54回日本神経学会学術大会
- Place of Presentation
  東京国際会議場
- Data Source
  KAKENHI-PROJECT-24591246
[Presentation] Aß重合体はタウの上流で作用する2013
- Author(s)
  松原悦朗，仲田祟，若佐谷保仁，瓦林毅，東海林幹夫
- Organizer
  第54回日本神経学会学術大会
- Place of Presentation
  東京国際会議場
- Data Source
  KAKENHI-PROJECT-24591246
[Presentation] アルツハイマー病モデルマウスにおけるアミロイドアンギオパチーの検討2013
- Author(s)
  瓦林毅，仲田祟，若佐谷保仁，大野英人，中畑直子，松原悦朗，東海林幹夫
- Organizer
  VSA-COG Japan 2013　第4回日本血管性認知障害研究会
- Place of Presentation
  東京コンファレンスセンター
- Data Source
  KAKENHI-PROJECT-24591246
[Presentation] 飢餓状態により横紋筋融解症を繰り返した新規遺伝子以上を有するグルタル酸尿症II型の治療例2013
- Author(s)
  仲田祟，若佐谷保仁，瓦林毅，松原悦朗，東海林幹夫，西野一三
- Organizer
  第92回日本神経学会東北地方会
- Place of Presentation
  ラ・プラス青い森（青森）
- Data Source
  KAKENHI-PROJECT-24591246
[Presentation] アミロイドアンギオパチーの検討2013
- Author(s)
  東海林幹夫，仲田崇，若佐谷保仁，中畑直子，瓦林毅
- Organizer
  脳心血管抗加齢研究会2013
- Place of Presentation
  梅田スカイビル（大阪）
- Data Source
  KAKENHI-PROJECT-24591246
[Presentation] 経口AbetaワクチンはADモデルマウスの行動障害を改善する．2013
- Author(s)
  瓦林毅，仲田祟，若佐谷保仁，松原悦朗，東海林幹夫
- Organizer
  第54回日本神経学会学術大会
- Place of Presentation
  東京国際フォーラム
- Data Source
  KAKENHI-PROJECT-24591246
[Presentation] 弘前大学神経内科ものわすれ外来における認知症リハビリテーション2013
- Author(s)
  中畑直子，仲田祟，若佐谷保仁，大野英人，瓦林毅，松原悦朗，東海林幹夫
- Organizer
  VSA-COG Japan 2013　第4回日本血管性認知障害研究会
- Place of Presentation
  東京コンファレンスセンター
- Data Source
  KAKENHI-PROJECT-24591246
[Presentation] Aβ重合体カスケード仮説の検証2013
- Author(s)
  松原悦朗，仲田祟，若佐谷保仁，大野英人，中畑直子，瓦林毅，東海林幹夫
- Organizer
  VSA-COG Japan 2013　第4回日本血管性認知障害研究会
- Place of Presentation
  東京コンファレンスセンター
- Data Source
  KAKENHI-PROJECT-24591246
[Presentation] 経口AbetaワクチンはADモデルマウスの行動障害を改善する2013
- Author(s)
  瓦林毅，仲田祟，若佐谷保仁，松原悦朗，東海林幹夫
- Organizer
  第54回日本神経学会学術大会
- Place of Presentation
  東京国際会議場
- Data Source
  KAKENHI-PROJECT-24591246
[Presentation] AsOligomerはlipidraftの信号伝達系を障害する2012
- Author(s)
  瓦林毅,仲田祟,若佐谷保仁,松原悦朗,東海林幹夫
- Organizer
  第53回日本神経学会学術大会
- Place of Presentation
  東京国際フォーラム
- Year and Date
  2012-05-25
- Data Source
  KAKENHI-PROJECT-23659450
[Presentation] Abeta oligomerはlipid raftsの信号伝達系を障害する．2012
- Author(s)
  瓦林毅，仲田祟，若佐谷保仁，松原悦朗，東海林幹夫
- Organizer
  第53回日本神経学会学術大会
- Place of Presentation
  東京国際フォーラム
- Data Source
  KAKENHI-PROJECT-24591246
[Presentation] 動物モデルを用いた脳アミロイドs蛋白の伝播性の検討2012
- Author(s)
  仲田崇,瓦林毅,若佐谷保仁,松原悦朗,東海林幹夫
- Organizer
  第53回日本神経学会学術大会
- Place of Presentation
  東京国際フォーラム
- Year and Date
  2012-05-25
- Data Source
  KAKENHI-PROJECT-23659450
[Presentation] Abeta重合化がアルツハイマー病の脳脊髄液中で亢進している．2012
- Author(s)
  松原悦朗，仲田崇, 中畑直子, 若佐谷保仁, 瓦林毅，東海林幹夫
- Organizer
  第29回日本老年医学会東北地方会
- Place of Presentation
  弘前
- Data Source
  KAKENHI-PROJECT-24591246
[Presentation] リポ蛋白がAs重合化の制御因子である2012
- Author(s)
  松原悦朗,仲田崇,中畑直子,若佐谷保仁,瓦林毅,東海林幹夫
- Organizer
  第53回日本神経学会学術大会
- Place of Presentation
  東京国際フォーラム
- Year and Date
  2012-05-23
- Data Source
  KAKENHI-PROJECT-23659450
[Presentation] As oligomers in lipid rafts impair signal transduction pathways in transgenic mouse model of Alzheimer's disease2012
- Author(s)
  Kawarabayashi T, Nakata T, Wakasaya Y, Matsubara E, Shoji M
- Organizer
  Neuroscience 2012, the Society for Neuroscience, 42th Annual Meeting
- Place of Presentation
  New Orleans, USA, Oct 13-17
- Data Source
  KAKENHI-PROJECT-23659450
[Presentation] sortilinがAbeta;重合体の神経毒性発現を制御している．2012
- Author(s)
  松原悦朗，瓦林毅，仲田崇，若佐谷保仁，東海林幹夫
- Organizer
  第31回日本認知症学会学術集会
- Place of Presentation
  つくば国際会議場　（茨城県）
- Data Source
  KAKENHI-PROJECT-24591246
[Presentation] Abeta oligomers in lipid rafts impair signal transduction pathways in transgenic mouse model of Alzheimer’s disease2012
- Author(s)
  Takeshi Kawarabayashi
- Organizer
  the Society for Neuroscience, 42th Annual Meeting
- Place of Presentation
  New Orleans
- Data Source
  KAKENHI-PROJECT-23659450
[Presentation] Abeta oligomers in lipid rafts impair signal transduction pathways in transgenic mouse model of Alzheimer’s disease.2012
- Author(s)
  Kawarabayashi T, Nakata T, Wakasaya Y, Matsubara E, Shoji M
- Organizer
  Neuroscience 2012, the Society for Neuroscience, 42th Annual Meeting
- Place of Presentation
  New Orleans　(アメリカ）
- Data Source
  KAKENHI-PROJECT-24591246
[Presentation] アルツハイマー病患者の脳脊髄液中ではAss重合化が亢進している2011
- Author(s)
  高村歩美, 仲田崇, 若佐谷保仁, 瓦林毅, 東海林幹夫, 松原悦朗
- Organizer
  第30回日本認知症学会学術集会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-21591069
[Presentation] Lipid raftsにおけるAβ oligomerによるtau蓄積の促進2011
- Author(s)
  瓦林毅,若佐谷保仁,仲田祟,高村歩美,中畑直子,松原悦朗,東海林幹夫
- Organizer
  第30回日本認知症学会学術集会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-21591069
[Presentation] Alzheimer病モデルマウスTg2576における脳amyloid angiopathyの検討2011
- Author(s)
  仲田崇, 瓦林毅, 若佐谷保仁、松原悦朗、東海林幹夫
- Organizer
  Vas-Cog Japan
- Place of Presentation
  東京
- Year and Date
  2011-08-20
- Data Source
  KAKENHI-PROJECT-21591069
[Presentation] DNAmicroarrayによる神経原線維変化の形成および神経細胞死に関与する因子の解析2011
- Author(s)
  若佐谷保仁,瓦林毅,松原悦朗,東海林幹夫
- Organizer
  第52回日本神経学会学術大会
- Place of Presentation
  名古屋
- Year and Date
  2011-05-19
- Data Source
  KAKENHI-PROJECT-23659450
[Presentation] Aβ oligomerはlipid raftsでtau蓄積を促進する2011
- Author(s)
  瓦林毅,若佐谷保仁,松原悦朗,東海林幹夫
- Organizer
  第52回日本神経学会学術大会
- Place of Presentation
  名古屋
- Data Source
  KAKENHI-PROJECT-21591069
[Presentation] 認知症診療の最前線2011
- Author(s)
  瓦林毅
- Organizer
  第22回老年医学会東北地方会
- Place of Presentation
  弘前
- Year and Date
  2011-10-29
- Data Source
  KAKENHI-PROJECT-21591069
[Presentation] ものわすれ外来における脳脊髄液バイオマーカー測定の有用性について2011
- Author(s)
  瓦林毅,松原悦朗,東海林幹夫
- Organizer
  第53回老年医学会学術集会
- Place of Presentation
  新宿
- Data Source
  KAKENHI-PROJECT-21591069
[Presentation] アルツハイマー病と軽度認知障害の発症予測スクリーニングマーカーの検証2011
- Author(s)
  松原悦朗,高村歩美,若佐谷保仁,瓦林毅,東海林幹夫
- Organizer
  第52回日本神経学会学術大会
- Place of Presentation
  名古屋
- Year and Date
  2011-05-20
- Data Source
  KAKENHI-PROJECT-23659450
[Presentation] Ass oligomerはlipid raftsでtau蓄積を促進する2011
- Author(s)
  瓦林毅, 若佐谷保仁, 松原悦朗, 東海林幹夫
- Organizer
  第52回日本神経学会学術大会
- Place of Presentation
  名古屋
- Year and Date
  2011-05-19
- Data Source
  KAKENHI-PROJECT-21591069
[Presentation] Alzheimer病モデルマウスTg2576における脳amyloid angiopathyの検討2011
- Author(s)
  仲田崇, 瓦林毅, 若佐谷保仁、松原悦朗、東海林幹夫
- Organizer
  第22回老年医学会東北地方会
- Place of Presentation
  弘前
- Year and Date
  2011-10-29
- Data Source
  KAKENHI-PROJECT-21591069
[Presentation] DNA microarray解析による神経原線維変化の形成および神経細胞死に関与する因子の解析2011
- Author(s)
  若佐谷保仁, 瓦林毅, 中畑直子, 高村歩美, 松原悦朗, 東海林幹夫
- Organizer
  第52回日本神経学会学術大会
- Place of Presentation
  名古屋
- Year and Date
  2011-05-19
- Data Source
  KAKENHI-PROJECT-21591069
[Presentation] Asoligomerはlipidraftsでtau蓄積を促進する2011
- Author(s)
  瓦林毅,若佐谷保仁,松原悦朗,東海林幹夫
- Organizer
  第52回日本神経学会学術大会
- Place of Presentation
  名古屋
- Year and Date
  2011-05-20
- Data Source
  KAKENHI-PROJECT-23659450
[Presentation] 脳脊髄液tau上昇を認めたprogressive non-fluent aphasiaの一例2011
- Author(s)
  瓦林毅, 若佐谷保仁、中畑直子、仲田崇, 松原悦朗、東海林幹夫
- Organizer
  第22回老年医学会東北地方会
- Place of Presentation
  弘前
- Year and Date
  2011-10-29
- Data Source
  KAKENHI-PROJECT-21591069
[Presentation] Lipid raftsにおけるAss oligomerによるtau蓄積の促進2011
- Author(s)
  瓦林毅, 若佐谷保仁, 仲田崇, 高村歩美, 中畑直子, 松原悦朗, 東海林幹夫
- Organizer
  第30回日本認知症学会学術集会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-21591069
[Presentation] アルツハイマー病と軽度認知障害の発症予測スクリーニングマーカーの検証2011
- Author(s)
  松原悦朗,高村歩美,若佐谷保仁,瓦林毅,東海林幹夫
- Organizer
  第52回日本神経学会学術大会
- Place of Presentation
  名古屋
- Data Source
  KAKENHI-PROJECT-21591069
[Presentation] Aβ重合体制御よるタウオパチー発症予防の検証.2010
- Author(s)
  高村歩美, 瓦林毅, 東海林幹夫, 松原悦朗
- Organizer
  第29回日本認知症学会学術集会
- Place of Presentation
  ウインクあいち(名古屋)
- Data Source
  KAKENHI-PROJECT-21591069
[Presentation] Aβ重合体制御よるタウオパチー発症予防の検証2010
- Author(s)
  高村歩美,瓦林毅,東海林幹夫,松原悦朗
- Organizer
  第29回日本認知症学会学術集会
- Place of Presentation
  名古屋
- Data Source
  KAKENHI-PROJECT-21591069
[Presentation] DNA microarray解析による神経原線維変化の形成および神経細胞死に関与する因子の解析.2010
- Author(s)
  瓦林毅, 若佐谷保仁, 高村歩美, 中畑直子, 渡辺有希子, 渡辺光法, 松原悦朗, 東海林幹夫
- Organizer
  第29回日本認知症学会学術集会
- Place of Presentation
  ウインクあいち(名古屋)
- Data Source
  KAKENHI-PROJECT-21591069
[Presentation] Factors responsible for neurofibrillary tangle formation and neuronal cell losses in tauopathy brains2010
- Author(s)
  Kawarabayashi T, Wakasaya Y, Watanabe M, Yamamoto-Watanabe Y, Takamura A, Nakahata N, Matsubara E, Shoji M
- Organizer
  12th Meeting of Hirosaki International Forum of Medical Science
- Place of Presentation
  Hirosaki
- Year and Date
  2010-10-29
- Data Source
  KAKENHI-PROJECT-21591069
[Presentation] Critical illness polyneuropathyを併発した行MuSk抗体陽性重症筋無力症の1剖検例.2010
- Author(s)
  渡辺有希子, 渡辺光法, 若佐谷保仁, 瓦林毅, 松原悦朗, 東海林幹夫, 若林孝一, 佐藤冬樹, 鬼島宏, 元村政勝
- Organizer
  第86回日本神経学会東北地方会
- Place of Presentation
  フォレスト仙台(仙台)
- Year and Date
  2010-03-06
- Data Source
  KAKENHI-PROJECT-21591069
[Presentation] 第52回日本老年医学会学術集2010
- Author(s)
  瓦林毅, 中畑直子, 松原悦朗, 東海林幹夫
- Organizer
  もの忘れ外来の軽度認知障害診断における日本版Wechsler memory scale revisedの有用性(第二報).
- Place of Presentation
  神戸国際会議場(神戸)
- Data Source
  KAKENHI-PROJECT-21591069
[Presentation] Aβオリゴマー特異的受動免疫予防法の開発2010
- Author(s)
  松原悦朗,高村歩美,若佐谷保仁,渡辺有希子,中畑直子,渡辺光法,瓦林毅,東海林幹夫
- Organizer
  第51回日本神経学会総会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-21591069
[Presentation] Factors responsible for neurofibrillary tangle formation and neuronal cell loss in tauopathy brains.2010
- Author(s)
  Kawarabayashi T, Wakasaya Y, Watanabe M, Yamamoto-Watanabe Y, Takamura A, Ma tsubara E, Shoji M
- Organizer
  Neuroscience 2010, the Society for Neuroscience, 40＾<th> Annual Meeting
- Place of Presentation
  San Diego Convention Center(San Diego)
- Data Source
  KAKENHI-PROJECT-21591069
[Presentation] DNA microarray解析による神経原線維変化の形成および神経細胞死に関与する因子の解析2010
- Author(s)
  瓦林毅,若佐谷保仁,高村歩美,中畑直子,渡辺有希子,渡辺光法,松原悦朗,東海林幹夫
- Organizer
  第29回日本認知症学会学術集会
- Place of Presentation
  名古屋
- Data Source
  KAKENHI-PROJECT-21591069
[Presentation] Posterior cortical atrophy の1例2010
- Author(s)
  若佐谷保仁,中畑直子,渡辺有希子,渡辺光法,瓦林毅,松原悦朗,東海林幹夫
- Organizer
  第87回日本神経学会東北地方会
- Place of Presentation
  山形
- Year and Date
  2010-09-11
- Data Source
  KAKENHI-PROJECT-21591069
[Presentation] Posterior cortical atrophyの1例.2010
- Author(s)
  若佐谷保仁, 中畑直子, 渡辺有希子, 渡辺光法, 瓦林毅, 松原悦朗, 東海林幹夫
- Organizer
  第87回日本神経学会東北地方会
- Place of Presentation
  大手門パルズ(山形)
- Year and Date
  2010-09-11
- Data Source
  KAKENHI-PROJECT-21591069
[Presentation] 弘前大学病院もの忘れ外来における脳血管性認知症の検討.2010
- Author(s)
  東海林幹夫, 瓦林毅, 中畑直子, 若佐谷保仁, 渡辺有希子, 渡辺光法, 松原悦朗
- Organizer
  第1回日本脳血管性認知障害研究会
- Place of Presentation
  東京コンファランスセンター品川(東京)
- Year and Date
  2010-08-28
- Data Source
  KAKENHI-PROJECT-21591069
[Presentation] 複数の脳血管障害のリスクファクターを有し2010
- Author(s)
  渡辺光法,足立芳樹,渡辺有希子,白濱育美,高村歩美,中畑直子,若佐谷保仁,瓦林毅,松原悦朗,東海林幹夫
- Organizer
  第35回脳卒中学会総会
- Place of Presentation
  岩手
- Data Source
  KAKENHI-PROJECT-21591069
[Presentation] もの忘れ外来の軽度認知障害診断における日本版Wechsler memory scale revisedの有用性(第二報)2010
- Author(s)
  瓦林毅,中畑直子,若佐谷保仁,渡辺有希子,渡辺光法,高村歩美,松原悦朗,東海林幹夫
- Organizer
  日本老年医学会東北地方会
- Place of Presentation
  福島
- Year and Date
  2010-10-30
- Data Source
  KAKENHI-PROJECT-21591069
[Presentation] Critical illness polyneuropathyを併発した行Musk抗体陽性重症筋無力症の1剖検例2010
- Author(s)
  渡辺有希子,渡辺光法,若佐谷保仁,瓦林毅,松原悦朗,東海林幹夫,若林孝一,佐藤冬樹,鬼島宏,元村政勝
- Organizer
  第86回日本神経学会東北地方会
- Place of Presentation
  仙台
- Year and Date
  2010-03-06
- Data Source
  KAKENHI-PROJECT-21591069
[Presentation] 弘前大学病院もの忘れ外来における脳血管性認知症の検討2010
- Author(s)
  東海林幹夫,瓦林毅,中畑直子,若佐谷保仁,渡辺有希子,渡辺光法,松原悦朗
- Organizer
  第1回日本脳血管性認知障害研究会
- Place of Presentation
  東京コンファランスセンター品川
- Year and Date
  2010-08-28
- Data Source
  KAKENHI-PROJECT-21591069
[Presentation] もの忘れ外来の軽度認知障害診断における日本版Wechslermemoryscalerevisedの有用性(第二報)2010
- Author(s)
  瓦林毅, 中畑直子, 若佐谷保仁, 渡辺有希子, 渡辺光法, 高村歩美, 松原悦朗, 東海林幹夫
- Organizer
  日本老年医学会東北地方会
- Place of Presentation
  コラッセふくしま(福島)
- Year and Date
  2010-10-30
- Data Source
  KAKENHI-PROJECT-21591069
[Presentation] Alzheimer neuronal degeneration : extracellular vs. intracellular Aβ oligomers2010
- Author(s)
  Takamura A, Kawarabayashi T, Matsubara T, Shoji M, Matsubara E
- Organizer
  Alzheimer's Association 2010 International Conference on Alzheimer's disease (ICAD)
- Place of Presentation
  Honolulu
- Data Source
  KAKENHI-PROJECT-21591069
[Presentation] 第51回日本神経学会総会2010
- Author(s)
  瓦林毅, 若佐谷保仁, 渡辺有希子, 渡辺光法, 松原悦朗, 東海林幹夫
- Organizer
  lipid raftsは神経変性疾患の共通した蛋白凝集開始部位である.
- Place of Presentation
  東京国際フォーラム(東京)
- Data Source
  KAKENHI-PROJECT-21591069
[Presentation] もの忘れ外来の軽度認知障害診断における日本版Wechsler memory scale revisedの有用性(第二報)2010
- Author(s)
  瓦林毅,中畑直子,松原悦朗,東海林幹夫
- Organizer
  第52回日本老年医学会学術集会
- Place of Presentation
  神戸
- Data Source
  KAKENHI-PROJECT-21591069
[Presentation] ALS6の臨床遺伝および病理学的検討2010
- Author(s)
  渡辺光法,渡辺有希子,岡本幸市,藤田行雄,池田将樹,中里洋一,白濱育美,高村歩美,瓦林毅,松原悦朗,池田佳生,若佐谷保仁,東海林幹夫
- Organizer
  第51回日本神経学会総会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-21591069
[Presentation] Neuroscience 20102010
- Author(s)
  Kawarabayashi T, Wakasaya Y, Watanabe M, Yamamoto-Watanabe Y, Takamura A, Matsubara E, Shoji M, Factors responsible for neurofibrillary tangle formation and neuronal cell loss in tauopathy brains
- Organizer
  the Society for Neuroscience, 40^<th> Annual Meeting
- Place of Presentation
  San Diego
- Data Source
  KAKENHI-PROJECT-21591069
[Presentation] 第51回日本神経学会総会2010
- Author(s)
  松原悦朗, 高村歩美, 若佐谷保仁, 渡辺有希子, 中畑直子, 渡辺光法, 瓦林毅, 東海林幹夫
- Organizer
  ABオリゴマー特異的受動免疫予防法の開発.
- Place of Presentation
  東京国際フォーラム(東京)
- Data Source
  KAKENHI-PROJECT-21591069
[Presentation] 第51回日本神経学会総会2010
- Author(s)
  渡辺光法, 渡辺有希子, 岡本幸市, 藤田行雄, 池田将樹, 中里洋一, 白濱育美, 高村歩美, 瓦林毅, 松原悦朗, 池田佳生, 若佐谷保仁, 東海林幹夫
- Organizer
  ALS6の臨床遺伝および病理学的検討
- Place of Presentation
  東京国際フォーラム(東京)
- Data Source
  KAKENHI-PROJECT-21591069
[Presentation] Factors responsible for neurofibrillary tangle formation and neuronal cell death in tauopathy brains2010
- Author(s)
  Shoji M, Kawarabayashi T, Wakasaya Y, Takamura A, Watanabe Y, Watanabe M, Matsubara E
- Organizer
  Alzheimer's Association 2010 International Conference on Alzheimer's disease (ICAD)
- Place of Presentation
  Honolulu
- Data Source
  KAKENHI-PROJECT-21591069
[Presentation] 複数の脳血管障害のリスクファクターを有し,高齢で発症したCADASILの1例.2010
- Author(s)
  渡辺光法, 足立芳樹, 渡辺有希子, 白濱育美, 高村歩美, 中畑直子, 若佐谷保仁, 瓦林毅, 松原悦朗, 東海林幹夫
- Organizer
  第35回脳卒中学会総会
- Place of Presentation
  岩手県民会館(盛岡)
- Data Source
  KAKENHI-PROJECT-21591069
[Presentation] lipid raftsは神経変性疾患の共通した蛋白凝集開始部位である2010
- Author(s)
  瓦林毅,若佐谷保仁,渡辺有希子,渡辺光法,松原悦朗,東海林幹夫
- Organizer
  第51回日本神経学会総会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-21591069
[Presentation] PAとPSPの重要な画像上の鑑別点.2009
- Author(s)
  倉田智子, 林健, 村上哲郎, 宮崎一徳, 森本展年, 太田康之, 池田雅美, 武久康, 永井真貴子, 池田佳生, 瓦林毅, 高尾芳樹, 大田泰正, 針谷康夫, 真邊泰宏, 神谷達司, 東海林幹夫, 阿部康二
- Organizer
  第50回日本神経学会総会
- Place of Presentation
  仙台
- Data Source
  KAKENHI-PROJECT-21591069
[Presentation] The clinical characterization of the Japanese pedigree of FAD with PS1 H163R mutation.2009
- Author(s)
  Miyagawa T, Iwata A, Kowa H, Kawarabayashi T, Shoji M, Tsuji S, Momose T, Kojima Y
- Organizer
  Alzheimer's Association 2009 International Conference on Alzheimer's disease(ICAD)
- Place of Presentation
  Vienna
- Data Source
  KAKENHI-PROJECT-21591069
[Presentation] Tauopathyによる神経細胞死を誘導する因子の解析.2009
- Author(s)
  若佐谷保仁, 瓦林毅, 清野祐輔, 渡辺有希子, 渡辺光法, 松原悦朗, 東海林幹夫
- Organizer
  第50回日本神経学会総会
- Place of Presentation
  仙台
- Data Source
  KAKENHI-PROJECT-21591069
[Presentation] Niemann-Pick type C1遺伝子のloss of functionはlipid raftsでtau蓄積を起こす.2009
- Author(s)
  瓦林毅, 清野祐輔, 若佐谷保仁, 渡辺有希子, 渡辺光法, 松原悦朗, 東海林幹夫
- Organizer
  第50回日本神経学会総会
- Place of Presentation
  仙台
- Data Source
  KAKENHI-PROJECT-21591069
[Presentation] Niemann-Pick type C1遺伝子のloss of functionはlipid raftsでtau蓄積を促進する.2009
- Author(s)
  瓦林毅, 若佐谷保仁, 渡辺有希子, 中畑直子, 高村歩美, 渡辺光法, 松原悦朗, 東海林幹夫
- Organizer
  第28回日本認知症学会学術集会
- Place of Presentation
  仙台
- Data Source
  KAKENHI-PROJECT-21591069
[Presentation] Measurement of cystatin C in cerebrospinal fluid of neurological disorders and analyses of +73 G/A polymorphism2009
- Author(s)
  Watanabe T, Yamamoto-Watanabe Y, Akimoto H, Sugimoto K, Yasujima M, Kawarabayashi T, Takamura A, Nakahata N, Shirahama I, Wakasaya Y, Matsubara E, Shoji M
- Organizer
  第32回日本分子生物学会年会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-21591069
[Presentation] The clinical characterization of the Japanese pedigree of FAD with PS1 H163R mutation2009
- Author(s)
  Miyagawa T, Iwata A, Kowa H, Kawarabayashi T, Shoji M, Tsuji S, Momose T, Kojima Y
- Organizer
  Alzheimer's Association 2009 International Conference on Alzheimer's disease (ICAD)
- Place of Presentation
  Vienna
- Data Source
  KAKENHI-PROJECT-21591069
[Presentation] Aβ amyloid accelerates accumulation of phosphorylated tau neuronal cytoplasm and processes of double transgenic mice2009
- Author(s)
  Seino Y, Kawarabayashi T, Wakasaya Y, Takamura A, Nakahata N, Watanabe Y, Watanabe M, Matsubara E, Shoji M
- Organizer
  11th Meeting of Hirosaki International Forum of Medical Science
- Place of Presentation
  Hirosaki
- Year and Date
  2009-03-27
- Data Source
  KAKENHI-PROJECT-19590976
[Presentation] Accumulation of protein in lipid rafts in mouse models of neurodegenerative diseases.2009
- Author(s)
  Kawarabayashi T, Wakasaya Y, Seino Y, Takamura A, Nakahata N, Watanabe Y, Watanabe M, Matsubara E, Shoj M
- Organizer
  Neuroscience 2009, the Society for Neuroscience, 39^<th> Annual Meeting
- Place of Presentation
  Chicago
- Data Source
  KAKENHI-PROJECT-21591069
[Presentation] Aβアミロイドによるタウ蓄積促進の検討.2009
- Author(s)
  清野祐輔, 瓦林毅, 若佐谷保仁, 渡辺有希子, 高村歩美, 中畑直子, 渡辺光法, 松原悦朗, 東海林幹夫
- Organizer
  第50回日本神経学会総会
- Place of Presentation
  仙台
- Data Source
  KAKENHI-PROJECT-21591069
[Presentation] Four-and-a-half LIM domain 1 (FHL1)遺伝子に異常を認めたreducing body myopathyの1例2009
- Author(s)
  瓦林毅,清野祐輔,若佐谷保仁,渡辺有希子,渡辺光法,松原悦朗,東海林幹夫,林由起子,西野一三
- Organizer
  第85回日本神経学会東北地方会
- Place of Presentation
  福島
- Year and Date
  2009-09-12
- Data Source
  KAKENHI-PROJECT-21591069
[Presentation] もの忘れ外来の軽度認知障害診断における日本版ウエクスラー記憶検査法(WMS-R)の有効性.2009
- Author(s)
  東海林幹夫, 中畑直子, 瓦林毅, 松原悦朗
- Organizer
  第51回日本老年医学会学術集会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-21591069
[Presentation] ApoE-Aβ複合体がアルツハイマー病患者脳脊髄液中で増加している.2009
- Author(s)
  松原悦朗, 高村歩美, 清野祐輔, 若佐谷保仁, 渡辺有希子, 渡辺光法, 瓦林毅, 東海林幹夫
- Organizer
  第50回日本神経学会総会
- Place of Presentation
  仙台
- Data Source
  KAKENHI-PROJECT-21591069
[Presentation] もの忘れ外来の軽度認知障害診断における日本版Wechsler memory scale revisedの有用性(第二報)2009
- Author(s)
  中畑直子,若佐谷保仁,高村歩美,渡辺有希子,渡辺光法,瓦林毅,松原悦朗,東海林幹夫
- Organizer
  第28回日本認知症学会学術集会
- Place of Presentation
  仙台
- Data Source
  KAKENHI-PROJECT-21591069
[Presentation] Aβオリゴマー特異的モノクローナル抗体の作用機序とAβオリゴマー毒性発現機序の解明2009
- Author(s)
  高村歩美,岡本康秀,中畑直子,若佐谷保仁,渡辺有希子,渡辺光法,瓦林毅,東海林幹夫,松原悦朗
- Organizer
  第28回日本認知症学会学術集会
- Place of Presentation
  仙台
- Data Source
  KAKENHI-PROJECT-21591069
[Presentation] 軽度認知障害診断にWechsler memory scale revisedは有用である.2009
- Author(s)
  瓦林毅, 中畑直子, 渡辺光法, 渡辺有希子, 若佐谷保仁, 松原悦朗, 東海林幹夫
- Organizer
  第20回日本老年医学会東北地方会
- Place of Presentation
  盛岡
- Year and Date
  2009-10-31
- Data Source
  KAKENHI-PROJECT-21591069
[Presentation] Tauopathyによる神経細胞死を誘導する因子の解析2009
- Author(s)
  若佐谷保仁,瓦林毅,清野祐輔,渡辺有希子,渡辺光法,松原悦朗,東海林幹夫
- Organizer
  第50回日本神経学会総会
- Place of Presentation
  仙台
- Data Source
  KAKENHI-PROJECT-21591069
[Presentation] 神経変性疾患における脳脊髄液シスタチンCの測定.2009
- Author(s)
  渡辺光法, 渡辺有希子, 秋元広之, 杉本一博, 保嶋実, 瓦林毅, 高村歩美, 中畑直子, 白濱育美, 若佐谷保仁, 清野祐輔, 松原悦朗, 東海林幹夫
- Organizer
  第50回日本神経学会総会
- Place of Presentation
  仙台
- Data Source
  KAKENHI-PROJECT-21591069
[Presentation] Analysis of factors that induCe neuronal death in tau transgenic mice2009
- Author(s)
  Wakasaya Y, Kawarabayashi T, Seino Y, Takamura A, Nakahata N, Watanabe Y, Watanabe M, Matsubara E, Shoji M
- Organizer
  11th Meeting of Hirosaki International Forum of Medical Science
- Place of Presentation
  Hirosaki
- Year and Date
  2009-03-27
- Data Source
  KAKENHI-PROJECT-19590976
[Presentation] Four-and-a-half LIM domain 1(FHL1)遺伝子に異常を認めたreducing body myopathyの1例.2009
- Author(s)
  瓦林毅, 清野祐輔, 若佐谷保仁, 渡辺有希子, 渡辺光法, 松原悦朗, 東海林幹夫, 林由起子, 西野一三
- Organizer
  第85回日本神経学会東北地方会
- Place of Presentation
  福島
- Year and Date
  2009-09-12
- Data Source
  KAKENHI-PROJECT-21591069
[Presentation] Niemann-Pick type C1遺伝子のloss of functionはlipid raftsでtau蓄積を促進する2009
- Author(s)
  瓦林毅, 若佐谷保仁, 渡辺有希子, 中畑直子, 高村歩美, 渡辺光法, 松原悦朗, 東海林幹夫
- Organizer
  第28回日本認知症学会学術集会
- Place of Presentation
  仙台
- Data Source
  KAKENHI-PROJECT-19390233
[Presentation] Measurement of cystatin C in cerebrospinal fluid of neurological disorders and analyses of +73 G/A polymorphism.2009
- Author(s)
  Watanabe T, Yamamoto-Watanabe Y, Akimoto H, Sugimoto K, Yasujima M, Kawarabayashi T, Takamura A, Nakahata N, Shirahama I, Wakasaya Y, Matsubara E, Shoji M
- Organizer
  第32回日本分子生物学会年会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-21591069
[Presentation] 神経変性疾患における脳脊髄液シスタチンC測定の意義2009
- Author(s)
  渡辺光法,渡辺有希子,秋元広之,杉本一博,保嶋実,瓦林毅,高村歩美,中畑直子,白濱育美,若佐谷保仁,清野祐輔,松原悦朗,東海林幹夫
- Organizer
  50回日本神経学会総会
- Place of Presentation
  仙台
- Data Source
  KAKENHI-PROJECT-21591069
[Presentation] Accumulation of protein in lipid rafts in mouse models of neurodegenerative diseases2009
- Author(s)
  Kawarabayashi T, Seino Y, Wakasaya Y, Takamura A, Nakahata N, Watanabe Y, Watanabe M, Matsubara E, Shoji M
- Organizer
  11th Meeting of Hirosaki International Forum of Medical Science
- Place of Presentation
  Hirosaki
- Year and Date
  2009-05-29
- Data Source
  KAKENHI-PROJECT-19590976
[Presentation] Enhanced accumulation of phosphorylated α-synuclein in doubly transgenic mice expressing mutant βAPP and PS-12009
- Author(s)
  Kurata T, Kawarabayashi T Ikeda Y, Murakami T, Miyazaki K, Morimoto N, Ota Y, Takehisa Y, Nagai M, Ikeda M, Matsubara E, Westaway D, St. George Hyslop P, Harigaya Y, Shoji M, Abe K
- Organizer
  11th Meeting of Hirosaki International Forum of Medical Science
- Place of Presentation
  Hirosaki
- Year and Date
  2009-03-27
- Data Source
  KAKENHI-PROJECT-19590976
[Presentation] もの忘れ外来の軽度認知障害診断における日本版Wechsler memory scale revised の有用性2009
- Author(s)
  中畑直子,清野祐輔,若佐谷保仁,高村歩美,渡辺有希子,渡辺光法,瓦林毅,松原悦朗,東海林幹夫
- Organizer
  第11回日本早期認知症学会
- Place of Presentation
  八戸
- Data Source
  KAKENHI-PROJECT-21591069
[Presentation] Accumulation of protein in lipid rafts in mouse models of neurodegenerative diseases.2009
- Author(s)
  Kawarabayashi T, Wakasaya Y, Seino Y, Takamura A, Nakahata N, Watanabe Y, Watanabe M, Matsubara E, Shoji M
- Organizer
  Neuroscience 2009, the Society for Neuroscience, 39^<th> Annual Meeting
- Place of Presentation
  Chicago
- Data Source
  KAKENHI-PROJECT-19390233
[Presentation] Tauopathyによる神経細胞死を誘導する因子の解析2009
- Author(s)
  若佐谷保仁, 瓦林毅, 清野祐輔, 渡辺有希子, 渡辺光法, 松原悦朗, 東海林幹夫
- Organizer
  第50回日本神経学会総会
- Place of Presentation
  仙台
- Data Source
  KAKENHI-PROJECT-19390233
[Presentation] Niemann-Pick type C1遺伝子のloss of functionはlipid raftsでtau蓄積を起こす2009
- Author(s)
  瓦林毅,清野祐輔,若佐谷保仁,渡辺有希子,渡辺光法,松原悦朗,東海林幹夫
- Organizer
  第50回日本神経学会総会
- Place of Presentation
  仙台
- Data Source
  KAKENHI-PROJECT-21591069
[Presentation] ApoE-Aβ複合体がアルツハイマー病患者脳脊髄液中で増加している2009
- Author(s)
  松原悦朗,高村歩美,清野祐輔,若佐谷保仁,渡辺有希子,渡辺光法,瓦林毅,東海林幹夫
- Organizer
  第50回日本神経学会総会
- Place of Presentation
  仙台
- Data Source
  KAKENHI-PROJECT-21591069
[Presentation] The clinical characterization of the Japanese pedigree of FAD with PS1 H163R mutation.2009
- Author(s)
  Miyagawa T, Iwata A, Kowa H, Kawarabayashi T, Shoji M, Tsuji S, Momose T, Kojima Y
- Organizer
  Alzheimer's Association 2009 International Conference on Alzheimer's disease(ICAD)
- Place of Presentation
  Vienna
- Data Source
  KAKENHI-PROJECT-19390233
[Presentation] Niemann-Pick type C1遺伝子のloss of functionはlipid raftsでtau蓄積を促進する2009
- Author(s)
  瓦林毅,若佐谷保仁,渡辺有希子,中畑直子,高村歩美,渡辺光法,松原悦朗,東海林幹夫
- Organizer
  第28回日本認知症学会学術集会
- Place of Presentation
  仙台
- Data Source
  KAKENHI-PROJECT-21591069
[Presentation] Assオリゴマー特異的モノクローナル抗体の作用機序とAssオリゴマー毒性発現機序の解明2009
- Author(s)
  高村歩美, 岡本康秀, 中畑直子, 若佐谷保仁, 渡辺有希子, 渡辺光法, 瓦林毅, 東海林幹夫, 松原悦朗
- Organizer
  第28回日本認知症学会学術集会
- Place of Presentation
  仙台
- Data Source
  KAKENHI-PROJECT-21591069
[Presentation] Clinical and molecular genetic study of ataxia-ocular apraxia 2 andfunctional analyses of senataxin.2009
- Author(s)
  Watanabe M, Fujimuro M, Jackson M, Yamamoto-Watanabe Y, Kawarabayashi T, Takamura A, Nakahata N,. Shirahama I, Wakasaya Y, Seino Y, Matsubara E, Shoji M
- Organizer
  11th Meeting of Hirosaki International Forum of Medical Science
- Place of Presentation
  Hirosaki
- Year and Date
  2009-03-27
- Data Source
  KAKENHI-PROJECT-19590976
[Presentation] Aβアミロイドによるタウ蓄積促進の検討2009
- Author(s)
  清野祐輔,瓦林毅,若佐谷保仁,渡辺有希子,高村歩美,中畑直子,渡辺光法,松原悦朗,東海林幹夫
- Organizer
  第50回日本神経学会総会
- Place of Presentation
  仙台
- Data Source
  KAKENHI-PROJECT-21591069
[Presentation] 軽度認知障害診断にWechsler memory scale revised は有用である2009
- Author(s)
  瓦林毅,中畑直子,渡辺光法,渡辺有希子,若佐谷保仁,松原悦朗,東海林幹夫
- Organizer
  第20回日本老年医学会東北地方会
- Place of Presentation
  盛岡
- Year and Date
  2009-10-31
- Data Source
  KAKENHI-PROJECT-21591069
[Presentation] PAとPSPの重要な画像上の鑑別点2009
- Author(s)
  倉田智子,林健,村上哲郎,宮崎一徳,森本展年,太田康之,池田雅美,武久康,永井真貴子,池田佳生,瓦林毅,高尾芳樹,大田泰正,針谷康夫,真邊泰宏,神谷達司,東海林幹夫,阿部康二
- Organizer
  第50回日本神経学会総会
- Place of Presentation
  仙台
- Data Source
  KAKENHI-PROJECT-21591069
[Presentation] Accumulation of protein in lipid rafts in mouse models of neurodegenerative diseases. Neuroscience 20092009
- Author(s)
  Kawarabayashi T, Wakasaya Y, Seino Y, Takamura A, Nakahata N, Watanabe Y, Watanabe M, Matsubara E, Shoj M
- Organizer
  the Society for Neuroscience,39^<th> Annual Meeting
- Place of Presentation
  Chicago
- Data Source
  KAKENHI-PROJECT-21591069
[Presentation] もの忘れ外来の軽度認知障害診断における日本版ウエクスラー記憶検査法(WMS-R)の有効性2009
- Author(s)
  東海林幹夫,中畑直子,瓦林毅,松原悦朗
- Organizer
  第51回日本老年医学会学術集会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-21591069
[Presentation] もの忘れ外来の軽度認知障害診断における日本版Wechsler memory scale revisedの有用性2009
- Author(s)
  中畑直子, 清野祐輔, 若佐谷保仁, 高村歩美, 渡辺有希子, 渡辺光法, 瓦林毅, 松原悦朗, 東海林幹夫
- Organizer
  第11回日本早期認知症学会
- Place of Presentation
  八戸
- Data Source
  KAKENHI-PROJECT-21591069
[Presentation] CSF tau correlates with brain tau in tau transgenic mice2008
- Author(s)
  Kawarabayshi T, Wakasaya Y, Seino Y, Watanabe M, Kimura T, Suzuki C, Tomiy ama M, Matsubara E, Ishiguro K, Westaway D, St. Geo rge-Hyslop P, Shoji M
- Organizer
  International Conference on Alzheimer's Di sease
- Place of Presentation
  Chicago
- Year and Date
  2008-07-27
- Data Source
  KAKENHI-PROJECT-19390233
[Presentation] プランペキソール内服患者における下肢浮腫について2008
- Author(s)
  冨山誠彦, 木村珠喜, 新井陽, 鈴木千恵子, 瓦林毅, 東海林幹夫
- Organizer
  第49回日本神経学会総会
- Place of Presentation
  横浜
- Year and Date
  2008-05-17
- Data Source
  KAKENHI-PROJECT-19590976
[Presentation] Tauopahtyによる神経細胞死を誘導する因子の解析2008
- Author(s)
  若佐谷保仁, 清野祐輔, 瓦林毅, 中畑直子, 渡辺光法, 東海林幹夫
- Organizer
  日本認知症学会
- Place of Presentation
  前橋
- Year and Date
  2008-10-10
- Data Source
  KAKENHI-PROJECT-19390233
[Presentation] もの忘れ外来の軽度認知障害診断における日本版ウエクスラー記憶検査法(WMS-R)の有用性2008
- Author(s)
  中畑直子, 瓦林毅, 1若佐谷保仁, 渡辺光法, 東海林幹夫
- Organizer
  第27回日本認知症学会学術集会
- Place of Presentation
  前橋
- Year and Date
  2008-10-10
- Data Source
  KAKENHI-PROJECT-19590976
[Presentation] 低酸素脳症の体性感覚誘発電位-中潜時成分と予後についての検討2008
- Author(s)
  鈴木千恵子, 尾崎勇, 冨山誠彦, 瓦林毅, 東海林幹夫
- Organizer
  第49回日本神経学会総会
- Place of Presentation
  横浜
- Year and Date
  2008-05-16
- Data Source
  KAKENHI-PROJECT-19590976
[Presentation] 神経原線維変化と神経細胞死を再現するタウマウスモデルの作成2008
- Author(s)
  瓦林毅, 清野祐輔, 若佐谷保仁, 渡辺光則, 木村珠喜, 鈴木千恵子, 審山誠彦, 東海林幹夫, 松原悦朗, 池田将樹, 針谷康夫
- Organizer
  第50回日本老年医学会学術集会
- Place of Presentation
  千葉
- Year and Date
  2008-06-20
- Data Source
  KAKENHI-PROJECT-19590976
[Presentation] 神経原線維変化, 神経細胞死を再現するタウマウスモデルの検討2008
- Author(s)
  瓦林毅, 渡辺光法, 東海林幹夫
- Organizer
  第6回神経科学研究会
- Place of Presentation
  東京
- Year and Date
  2008-09-20
- Data Source
  KAKENHI-PROJECT-19590976
[Presentation] L-Dopaによるパーキンソン病モデルラット線条体でのスパイン形態の変化2008
- Author(s)
  木村珠喜, 冨山誠彦, 新井陽, 鈴木千恵子, 渡辺光法, 瓦林毅, 東海林幹夫
- Organizer
  第49回日本神経学会総会
- Place of Presentation
  横浜
- Year and Date
  2008-05-17
- Data Source
  KAKENHI-PROJECT-19590976
[Presentation] Ataxia-ocular apraxia2(AOA2)の臨床遺伝字的検討とsenataxinの機能解析2008
- Author(s)
  渡辺光法, 藤室雅弘, 冨山誠彦, 瓦林毅, 鈴木千恵子, 木村珠喜, 三木康生, 若佐谷保仁, 清野祐輔, 東海林幹夫
- Organizer
  第49回日本神経学会総会
- Place of Presentation
  横浜
- Year and Date
  2008-05-15
- Data Source
  KAKENHI-PROJECT-19590976
[Presentation] 抗アミロイド蛋白40特異抗体を用いたアミロイドアンギオパチーの免疫療法2008
- Author(s)
  瓦林毅, 東海林幹夫
- Organizer
  第92回弘前医学会総会
- Place of Presentation
  弘前
- Year and Date
  2008-06-15
- Data Source
  KAKENHI-PROJECT-19590976
[Presentation] もの忘れ外来の軽度認知障害診断における日本語版ウエクスラー記憶検査法(WMS-R)の有用性2008
- Author(s)
  中畑直子, 瓦林毅, 清野祐輔, 若佐谷保仁, 渡辺光法, 東海林幹夫
- Organizer
  日本認知症学会
- Place of Presentation
  前橋
- Year and Date
  2008-10-10
- Data Source
  KAKENHI-PROJECT-19390233
[Presentation] L-Dopa誘発性ジスキネジアは淡蒼球内節GABAA受容体刺激により生じる2008
- Author(s)
  新井陽, 冨山誠彦, 木村珠喜, 鈴木千恵子, 瓦林毅, 東海林幹夫
- Organizer
  第49回日本神経学会総会
- Place of Presentation
  横浜
- Year and Date
  2008-05-15
- Data Source
  KAKENHI-PROJECT-19590976
[Presentation] 脳脊髄液タウは脳タウ蓄積と相関する2008
- Author(s)
  瓦林毅, 清野祐輔, 若佐谷保仁, 渡辺光法, 木村珠喜, 鈴木千恵子, 冨山誠彦, 東海林幹夫, 松原悦朗, 石黒幸一
- Organizer
  日本神経学会
- Place of Presentation
  横浜
- Year and Date
  2008-05-17
- Data Source
  KAKENHI-PROJECT-19390233
[Presentation] 脳脊髄液タウは脳タウ蓄積と相関する2008
- Author(s)
  瓦林毅, 清野祐輔, 若佐谷保仁, 渡辺光法, 木村珠喜, 鈴木千恵子, 冨山誠彦, 松原悦朗, 石黒幸一, 東海林幹夫
- Organizer
  第49回日本神経学会総会
- Place of Presentation
  横浜
- Year and Date
  2008-05-17
- Data Source
  KAKENHI-PROJECT-19590976
[Presentation] Aβアミロイドはタウ蓄積を促進する2008
- Author(s)
  清野祐輔, 瓦林毅, 若佐谷保仁, 渡辺光法, 木村珠喜, 鈴木千恵子, 冨山誠彦, 東海林幹夫, 松原悦朗
- Organizer
  日本神経学会
- Place of Presentation
  横浜
- Year and Date
  2008-05-16
- Data Source
  KAKENHI-PROJECT-19390233
[Presentation] 脳内AB蓄積予測マーカーの開発2008
- Author(s)
  高村歩美, 瓦林毅, 道川誠, 東海林幹夫, 松原悦朗
- Organizer
  第27回日本認知症学会学術集会
- Place of Presentation
  前橋
- Year and Date
  2008-10-10
- Data Source
  KAKENHI-PROJECT-19590976
[Presentation] CSF tau correlates with brain tau in tau transgenic mice2008
- Author(s)
  Kawarabayashi T, Seino1Y, Wakasaya1Y, Watanabe M, Kimura1T, Suzuki C, Tomiyama M, Matsubara E, Ishiguro K, Westaway D, St.George-Hyslop P, Shoji M
- Organizer
  ICAD2008
- Place of Presentation
  Chicago
- Year and Date
  2008-07-28
- Data Source
  KAKENHI-PROJECT-19590976
[Presentation] アルツハイマー病の超早期バイオマーカー開発2008
- Author(s)
  松原悦朗, 瓦林毅, 東海林幹夫
- Organizer
  第49回日本神経学会総会
- Place of Presentation
  横浜
- Year and Date
  2008-05-17
- Data Source
  KAKENHI-PROJECT-19590976
[Presentation] Clinical and molecular genetic study of ataxia-ocular apraxia 2 and functional analysis of senataxin2008
- Author(s)
  Watanabe M, Jackson M, Fujimuro M, Kawarabayashi T, Seino Y, Wakasaya Y, Yamamoto-Watanabe Y, Matsubara E
- Organizer
  Society for neuroscience
- Place of Presentation
  washington
- Year and Date
  2008-11-18
- Data Source
  KAKENHI-PROJECT-19390233
[Presentation] Ataxia-ocularapr axia2(AOA2)の臨床遺伝学的検討とsenataxinの機能解析2008
- Author(s)
  渡辺光法, 藤室雅弘, 冨山誠彦, 瓦林毅, 鈴木千恵子, 木村珠喜, 三木康生, 若佐谷保仁, 清野祐輔, 東海林幹夫
- Organizer
  日本神経学会
- Place of Presentation
  横浜
- Year and Date
  2008-05-16
- Data Source
  KAKENHI-PROJECT-19390233
[Presentation] 当科におけるもの忘れ外来と脳脊髄液診断の現状2008
- Author(s)
  若佐谷保仁, 瓦林毅, 中畑直子, 清野祐輔, 渡辺光法, 木村珠喜, 鈴木千恵子, 冨山誠彦, 東海林幹夫, 松原悦朗, 桑野良三
- Organizer
  日本神経学会
- Place of Presentation
  横浜
- Year and Date
  2008-05-16
- Data Source
  KAKENHI-PROJECT-19390233
[Presentation] Aβアミロイドはタウ蓄積を促進する2008
- Author(s)
  清野祐輔, 瓦林毅, 若佐省保仁, 渡辺光法, 木村珠喜, 鈴木千恵子, 冨山誠彦, 松原悦朗, 東海林幹夫
- Organizer
  第49回日本神経学会総会
- Place of Presentation
  横浜
- Year and Date
  2008-05-17
- Data Source
  KAKENHI-PROJECT-19590976
[Presentation] Tauopathyによる神経細胞死を誘導する因子の解析2008
- Author(s)
  若佐谷保仁, 清野祐輔, 瓦林毅, 中畑直子, 渡辺光法, 東海林幹夫
- Organizer
  第27回日本認知症学会学術集会
- Place of Presentation
  前橋
- Year and Date
  2008-10-10
- Data Source
  KAKENHI-PROJECT-19590976
[Presentation] Clinical and molecular genetic study of ataxia-ocular apraxia 2 and functional analysis of senataxin.2008
- Author(s)
  Watanabe M, Jackson M, Fujimuro M. Kawarabayashi T, Seino Y, Wakasaya Y, Yamamoto-Watanabe Y, Matsubara E, Shoii MClinical and molecular genetic study of ataxia-ocular apraxia 2 and functional analysis of senataxin
- Organizer
  the Society for Neuroscience, 38^h Annual Meeting
- Place of Presentation
  Washington D.C.
- Data Source
  KAKENHI-PROJECT-19590976
[Presentation] CSF Tau correlates with Brain Tau In Tau Transgenic Mice2008
- Author(s)
  Takeshi Kawarabayashi, Yusuke Seino, Yasuhito Wakasaya, Mitsunori Watanabe, Tamaki Kimura, Chieko Suzuki, Masahiko Tomiyama, Etsuro Matsubara, Koichi Ishiguro, David Westaway, Peter St. George-Hyslop, Mikio Shoji
- Organizer
  ICAD2008
- Place of Presentation
  Chicago
- Data Source
  KAKENHI-PROJECT-19390233
[Presentation] 神経原線維変化と神経細胞死を再現するタウマウスモテルの作成2008
- Author(s)
  瓦林毅, 清野祐輔, 若佐谷保仁, 渡辺光法, 木村珠喜, 鈴木千恵子, 冨山誠彦, 東海林幹夫, 松原悦朗, 池田将樹, 針谷康夫
- Organizer
  日本老年医学会
- Place of Presentation
  千葉
- Year and Date
  2008-06-20
- Data Source
  KAKENHI-PROJECT-19390233
[Presentation] 当科におけるもの忘れ外来と脳脊髄液診断の現状2008
- Author(s)
  君佐谷保仁, 瓦林毅, 中畑直子, 清野祐輔, 渡辺光法, 木村珠喜, 鈴木千恵子, 冨山誠彦, 東海林幹夫
- Organizer
  第49回日本神経学会総会
- Place of Presentation
  横浜
- Year and Date
  2008-05-17
- Data Source
  KAKENHI-PROJECT-19590976
[Presentation] Aβ oligomerは脳アミロイド蓄積を促進する2007
- Author(s)
  針谷康夫, 松原悦朗, 池田将樹、瓦林毅, 東海林幹夫
- Organizer
  第48回日本神経学会総会
- Place of Presentation
  名古屋
- Year and Date
  2007-05-16
- Data Source
  KAKENHI-PROJECT-19390233
[Presentation] Cortical neuronal and glial pathology in TgTauP301L transgenic mice the Society for Neuroscience2007
- Author(s)
  Kawarabayashi T, Seino Y, Wakasaya Y, Watanabe M, Suzuki C, Tomiyama M, Matsubara E, Egashira N, Takahashi M, Fujiwara M, Carlson GA, Westaway D, St.George-Hyslop P, Shoji M
- Organizer
  37^<th> Annual Meeting
- Place of Presentation
  San Diego
- Data Source
  KAKENHI-PROJECT-19590976
[Presentation] Cortical neuronal and glial pathology in TgTauP301L transgenic mice2007
- Author(s)
  T. Kawarabayashi, Y. Seino, Y. Wakasaya, M. Watanabe, C. Suzuki, M. Tomiyama, E. Matsubara, N. Egashira, M. Takahashi, M. Fujiwara, G. A. Carlson, D. Westaway, P. S. George-Hyslop, M. Shoji
- Organizer
  XVII WFN World Congress on Parkinson's Disease and Related Disorders
- Place of Presentation
  Amsterdam
- Data Source
  KAKENHI-PROJECT-19390233
[Presentation] Characterization of therapeutic antibody against Aβ oligomers for Alzheimer's disease2007
- Author(s)
  H. Sun, Y. Okamoto, T. Kawarabayashi, T. Yokoseki, M. Shibata, M. Morishima, Y. Saito, S. Murayama, Y. Ihara, M. Shoji, M. Michikawa, E. Matsubara
- Organizer
  Neuroscience 2007, the Society for Neuroscience
- Place of Presentation
  San Diego
- Data Source
  KAKENHI-PROJECT-19390233
[Presentation] Aβアミロイド蓄積は神経突起およびグリア細胞へのtau蓄積を促進する2007
- Author(s)
  清野祐輔, 瓦林毅, 若佐谷保仁, 新井陽, 木村珠喜, 鈴木千恵子, 冨山誠彦, 村上哲郎, 倉田智子, 松原悦朗, 東海林幹夫
- Organizer
  第48回日本神経学会総会
- Place of Presentation
  名古屋
- Year and Date
  2007-05-17
- Data Source
  KAKENHI-PROJECT-19390233
[Presentation] Aβアミロイド蓄積は神経突起およびグリア細胞へのtau蓄積を促進する.2007
- Author(s)
  清野祐輔, 瓦林毅, 若佐谷保仁, 新井陽, 木村珠喜, 鈴木千恵子, 冨山誠彦, 村上哲郎, 倉田智子, 松原悦朗, 東海林幹夫
- Organizer
  第48回日本神経学会総会
- Place of Presentation
  名古屋
- Year and Date
  2007-05-17
- Data Source
  KAKENHI-PROJECT-19590976
[Presentation] Analysis of amyloid angiopathy in Tg2576 Transgenic mouse model of Alzheimer's disease2007
- Author(s)
  Kawarabayashi T, Seino Y, Wakasaya Y, Kimura T, Suzuki C, Tomiyama M, Matsubara E, Shoji M
- Organizer
  The 23^<rd> International Synmpsium on Cerebralk Blood Flow, Metabolism & Function
- Place of Presentation
  Osaka
- Data Source
  KAKENHI-PROJECT-19590976
[Presentation] Enhanced GABA release in the medial globus pallidus of a rat model of L-DOPA-induced dyskinesia2007
- Author(s)
  Tomiyama M, Arai A, Kimura T, Watanabe M, Kawarabayashi T, Shoji M
- Organizer
  XVII WFN World Congress on Parkinson's Disease and Related Disorders
- Place of Presentation
  Amsterdam
- Data Source
  KAKENHI-PROJECT-19390233
[Presentation] Characterization of therapeutic antibody against Aβ oligomers for Alzheimer's disease.2007
- Author(s)
  Sun H, Okamoto Y, Kawarabayashi T, Yokoseki T, Shibata M, Morishima M, Saito Y, Murayama S, Ihara Y, Shoji M, Michikawa M, Matsubara E
- Organizer
  the Society for Neuroscience, 37th Annual Meeting
- Place of Presentation
  San Diego
- Year and Date
  2007-11-05
- Data Source
  KAKENHI-PROJECT-19590976
[Presentation] Analysis of amyloid angiopathy in Tg2576 Transgenic mouse model of Alzheimer's disease2007
- Author(s)
  T. Kawarabayashi, Y. Seino, Y. Wakasaya, T. Kimura, C. Suzuki, M. Tomiyama, E. Matsubara, M. Shoji
- Organizer
  Brain'07 and Brain PET'07
- Place of Presentation
  Osaka
- Data Source
  KAKENHI-PROJECT-19390233
[Presentation] Aβ accumulation causes potstsynaptic damage in Tg2576 mice.2007
- Author(s)
  Wakasaya Y, Seino Y, Kawarabayashi T, Watanabe M, Suzuki C, Tomiyama M, Matsubara E, Shoji M
- Organizer
  第26回日本認知症学会学術集会
- Place of Presentation
  大阪
- Data Source
  KAKENHI-PROJECT-19590976
[Presentation] Analysis of transgenic mice overexpressing mutant tau and GSK-3β2007
- Author(s)
  Ikeda M, Goris I, Sasaki A, Kawarabayashi T, Ishiguro K, Shoji M, Harigaya Y, Dieder M, Okamoto K.
- Organizer
  IPA 2007 Osaka Siver Congress
- Place of Presentation
  Osaka
- Data Source
  KAKENHI-PROJECT-19390233
[Presentation] Niemann-Pick type C1遺伝子のloss of functionはtauopathyを促進する2007
- Author(s)
  東海林幹夫, 瓦林毅, 清野祐輔, 若佐谷保仁, 新井陽, 木村珠喜, 鈴木千恵子, 冨山誠彦, 村上哲郎, 倉田智子, 松原悦朗, 東海林幹夫
- Organizer
  第48回日本神経学会総会
- Place of Presentation
  名古屋
- Year and Date
  2007-05-17
- Data Source
  KAKENHI-PROJECT-19390233
[Presentation] Analysis of phosphorylation of tau in transgenic mice overexpressing GSK-3β. the Society for Neuroscience2007
- Author(s)
  Ikeda M, Goris I, Sasaki A, Kawarabayashi T, Harigaya Y, Shoji M, Moechars D, Okamoto K
- Organizer
  37th Annual Meeting
- Place of Presentation
  San Diego
- Data Source
  KAKENHI-PROJECT-19590976
[Presentation] XVII WFN World Congress on Parkinson's Disease and Related Disorders2007
- Author(s)
  T Kimura, M Tomiyama, A Arai, C Suzuki, T Kawarabayashi, M Shoji. Onset age or treatment age: Whichis a more important risk factor for L-DOPA-induced dyskinesia in Park inson's disease?
- Organizer
  XVII WFN World Congress on Parkinson's Disease and Related Disorders
- Place of Presentation
  Amsterdam
- Data Source
  KAKENHI-PROJECT-19390233
[Presentation] Enhanced accumulation of phosphorylated α-synuclein in transgenic mice expressing APP and PS-12007
- Author(s)
  Kurata T, Kawarabayashi T, Murakami T, Nagai M, Takehisa Y, Hayashi T, Kamiya T, Shoji M, Abe K
- Organizer
  日本認知症学会
- Place of Presentation
  大阪
- Data Source
  KAKENHI-PROJECT-19390233
[Presentation] Niemann-Pick type C1遺伝子のloss of functionはtauopathyを促進する.2007
- Author(s)
  瓦林毅, 清野祐輔, 若佐谷保仁, 新井陽, 木村珠喜, 鈴木千恵子, 冨山誠彦, 村上哲郎, 倉田智子, 松原悦朗, 東海林幹夫
- Organizer
  第48回日本神経学会総会
- Place of Presentation
  名古屋
- Year and Date
  2007-05-17
- Data Source
  KAKENHI-PROJECT-19590976
[Presentation] 超高齢者集団認知症検診におけるMini-Mental State Examination(MMSE)の妥当性の検討2007
- Author(s)
  若佐谷保仁、清野祐輔、瓦林毅、三木康生、木村珠喜、鈴木千恵子、渡辺光法、冨山誠彦、桑野良三、東海林幹夫
- Organizer
  第48回日本神経学会総会
- Place of Presentation
  名古屋
- Year and Date
  2007-05-17
- Data Source
  KAKENHI-PROJECT-19390233
[Presentation] Aβ amyloid accelerates accumulation of tau in neuronal processes2007
- Author(s)
  Y. Seino, Y. Wakasaya, T. Kawarabayashi, M. Watanabe, C. Suzuki, M. Tomiyama, E. Matsubara, M. Shoji
- Organizer
  日本認知症学会
- Place of Presentation
  大阪
- Data Source
  KAKENHI-PROJECT-19390233
[Presentation] Cortical neuronal and glial pathology in TgTauP301L transgenic mice.2007
- Author(s)
  Kawarabayashi T, Seino Y, Wakasaya Y, Watanabe M, Suzuki C, Tomiyama M, Matsubara E, Egashira N, Takahashi M, Fujiwara M, Carlson GA, Westaway D, St. George-Hyslop P, Shoji M
- Organizer
  the Society for Neuroscience, 37th Annual Meeting
- Place of Presentation
  San Diego
- Year and Date
  2007-11-04
- Data Source
  KAKENHI-PROJECT-19590976
[Presentation] Characterization of therapeutic antibody against Aβ oligomers for Alzheimer's disease. the Society for Neuroscience2007
- Author(s)
  Sun H, Okamoto Y, Kawarabayashi T, Yokoseki T, Shibata M, Morishima M, Saito Y, Murayama S, Ihara Y, Shoji M, Michikawa M, Matsubara E
- Organizer
  37^<th> Annual Meeting
- Place of Presentation
  San Diego
- Data Source
  KAKENHI-PROJECT-19590976
[Presentation] Aβ amyloid accelerates accumulation of tau in neuronal processes.2007
- Author(s)
  Seino Y, Wakasaya Y, Kawarabayashi T, Watanabe M, Suzuki C, Tomiyama M, Matsubara E, Shoji M
- Organizer
  第26回日本認知症学会学術集会
- Place of Presentation
  大阪
- Data Source
  KAKENHI-PROJECT-19590976
[Presentation] Analysis of phosphorylation of tau in transgenic mice overexpressing GSK-3β.2007
- Author(s)
  Ikeda M, Goris I, Sasaki A, Kawarabayashi T, Harigaya Y, Shoji M, Moechars D, Okamoto K
- Organizer
  the Society for Neuroscience, 37th Annual Meeting
- Place of Presentation
  San Diego
- Year and Date
  2007-11-05
- Data Source
  KAKENHI-PROJECT-19590976
[Presentation] Analysis of phosphorylation of tau in transgenic mice overexpressing GSK-3β2007
- Author(s)
  Masaki Ikeda, Ilse Goris, Atsushi Sasaki, Takeshi Kawarabayashi, Yasuo Harigaya, Mikio Shoji, Dieder Moechars, Koichi Okamoto
- Organizer
  Neuroscience 2007, the Society for Neuroscience
- Place of Presentation
  San Diego
- Data Source
  KAKENHI-PROJECT-19390233
[Presentation] Multiple Sclerosis with chronic sialadenitis2007
- Author(s)
  Suzuki C, Tomiyama M, Kawarabayashi T, Shoji M, Baba M
- Organizer
  17th meeting of the European Neurological Society
- Place of Presentation
  Rhodes Greece
- Data Source
  KAKENHI-PROJECT-19590976
[Presentation] Analysis of transgenic mice overexpressing mutant tau and GSK-3β2007
- Author(s)
  Ikeda M, Goris I, Sasaki A, Kawarabayashi T, Ishiguro K, Shoji M, Harigaya Y, Westaway D, St George-Hyslop P, Moechars D, Okamoto K
- Organizer
  IPA 2007 Osaka Silver Congress of the International Psychiatrics Association
- Place of Presentation
  Osaka
- Data Source
  KAKENHI-PROJECT-19590976
[Presentation] Aβ accumulation causes postsynaptic damage in Tg2576 mice2007
- Author(s)
  Y. Wakasaya, Y. Seino, T. Kawarabayashi, M. Watanabe, C. Suzuki, M. Tomiyama, E. Matsubara, M. Shoji,
- Organizer
  日本認知症学会
- Place of Presentation
  大阪
- Data Source
  KAKENHI-PROJECT-19390233
[Presentation] Tg2576トランスジェニックマウスにおけるミクログリア活性化状態について2007
- Author(s)
  佐々木惇、東海林幹夫、瓦林毅、針谷康夫、池田将樹、中里洋一
- Organizer
  第49回日本神経病理学会総会学術研究会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-19390233
[Presentation] 超高齢者集団認知症検診におけるMini-Mental State Examination(MMSE)の妥当性の検討.2007
- Author(s)
  若佐谷保仁、清野祐輔、瓦林毅、三木康生、木村珠喜、鈴木千恵子、渡辺光法、冨山誠彦、桑野良三、東海林幹夫
- Organizer
  第48回日本神経学会総会
- Place of Presentation
  名古屋
- Year and Date
  2007-05-17
- Data Source
  KAKENHI-PROJECT-19590976
[Presentation] Analysis of amyloid angiopathy in Tg2576 Transgenic mouse model of Alzheimer's disease.2007
- Author(s)
  Kawarabayashi T, Seino Y, Wakasaya Y, Kimura T, Suzuki C, Tomiyama M, Matsubara E, Shoji M
- Organizer
  Brain'07 and Brain PET'07
- Place of Presentation
  Osaka
- Data Source
  KAKENHI-PROJECT-19590976
[Presentation] Enhanced accumulation of phosphorylated a-synuclein in double transgenic mice expressing mutant bAPP and presenilin-12007
- Author(s)
  Kurata T, Kawarabayashi T, Murakami T, Miyazaki K, Morimoto N, Ohta Y, Takehisa Y, Nagai M, Ikeda M, Matsubara E, Westaway D, yslop PS, Harigaya Y, Kamiya T, Shoji M, Abe K
- Organizer
  IPA 2007 Osaka Siver Congress
- Place of Presentation
  Osaka
- Data Source
  KAKENHI-PROJECT-19390233
[Presentation] Binding of Aβ oligomers and prion in lipid rafts of Alzheimer model mice.
- Author(s)
  Kawarabayashi T, Nakata T, Wakasaya Y, Matsubara E, Shoji M
- Organizer
  第55回日本神経学会学術大会
- Place of Presentation
  福岡国際会議場
- Year and Date
  2014-05-21 – 2014-05-24
- Data Source
  KAKENHI-PROJECT-24591246
[Presentation] Aβ oligomerはlipid raftsでprionと結合して信号伝達系を障害する．
- Author(s)
  瓦林毅，中村琢洋，仲田崇，若佐谷保仁，中畑直子，東海林幹夫
- Organizer
  第33回日本認知症学会学術集会
- Place of Presentation
  パシフィコ横浜
- Year and Date
  2014-11-29 – 2014-12-01
- Data Source
  KAKENHI-PROJECT-24591246
[Presentation] DNA microarray解析による神経原線維変化の形成および神経細胞死に関する因子の解析
- Author(s)
  若佐谷保仁，瓦林毅，松原悦朗，東海林幹夫
- Organizer
  第52回日本神経学会学術大会
- Place of Presentation
  名古屋
- Data Source
  KAKENHI-PROJECT-23659450
[Presentation] アルツハイマー病発症にlipid raftsが関与する．
- Author(s)
  瓦林毅
- Organizer
  第26回日本脳循環代謝学会総会
- Place of Presentation
  岡山コンベンションセンター
- Year and Date
  2014-11-21 – 2014-11-22
- Data Source
  KAKENHI-PROJECT-24591246
[Presentation] Aβ oligomers and prion in lipid rafts.
- Author(s)
  Kawarabayashi T, Nakata T, Wakasaya Y, Nakamura T, Nakahata N, Shoji M
- Organizer
  Alzheimer’s Association International Conference 2014
- Place of Presentation
  Copenhagen, Denmark
- Year and Date
  2014-07-12 – 2014-07-17
- Data Source
  KAKENHI-PROJECT-24591246
[Presentation] Abeta oligomerはlipid raftsでtau蓄積を促進する
- Author(s)
  瓦林毅，若佐谷保仁，松原悦朗，東海林幹夫
- Organizer
  第52回日本神経学会学術大会
- Place of Presentation
  名古屋
- Data Source
  KAKENHI-PROJECT-23659450
[Presentation] アルツハイマー病と軽度認知障害の発症予測スクリーニングマーカーの検証
- Author(s)
  松原悦朗，高村歩美，若佐谷保仁，瓦林毅，東海林幹夫
- Organizer
  第52回日本神経学会学術大会
- Place of Presentation
  名古屋
- Data Source
  KAKENHI-PROJECT-23659450

1. SHOJI Mikio (60171021)

# of Collaborated Projects: 8 results

# of Collaborated Products: 310 results
2. MATSBARA Etsuro (70219468)

# of Collaborated Projects: 6 results

# of Collaborated Products: 93 results
3. WATANABE Mitsunori (90251107)

# of Collaborated Projects: 3 results

# of Collaborated Products: 117 results
4. NAKAMURA Takumi (80744193)

# of Collaborated Projects: 3 results

# of Collaborated Products: 35 results
5. TOMIYAMA Masahiko (40311542)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
6. ABE Koji (20212540)

# of Collaborated Projects: 2 results

# of Collaborated Products: 3 results
7. WAKASAYA Yasuhito (10598725)

# of Collaborated Projects: 1 results

# of Collaborated Products: 12 results
8. IKEDA Masaki (50222899)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
9. TAKEHISA Yasushi (00379752)

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
10. NAGAI Makiko (80420488)

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
11. HAYASHI Takeshi (40314679)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. MURAKAMI Tetsuro (70403475)

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
13. ITO Nobuo (10362344)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
14. 鈴木千恵子 (50396404)

# of Collaborated Projects: 1 results

# of Collaborated Products: 22 results
15. 富山誠彦

# of Collaborated Projects: 0 results

# of Collaborated Products: 19 results
16. 森島真帆

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Kawarabayashi Takeshi 瓦林 毅

Takeshi Kawarabayashi 瓦林 毅

KAWARABAYASHI Takeshi 瓦林 毅

Research Projects

Research Products

Co-Researchers

Analysis of Alzheimer's disease targeting lipid rafts and exosomePrincipal Investigator

Principal Investigator

Project Period (FY)

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Development of prevention of Alzheimer's disease using transgenic soybean expressing amyloid beta proteinPrincipal Investigator

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Identification of neurotoxic Abeta oligomers and development of therapy against themPrincipal Investigator

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Development and clinical application of disease modifying drug for Alzheimer's Disease

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Analysis of pathogenesis of neurodegenerative diseases targeting synapsePrincipal Investigator

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Study for novel biomarkers for Alzheimer's disease

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Development of therapies targeting pathogenic oligomers in lipid raftsPrincipal Investigator

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Development and clinical application of novel methods for diagnosis and therapy of Alzheimer disease by regulation of neurotoxic oligomer

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Development of therapy targeting amyloid β protein oligomer in lipid raftsPrincipal Investigator

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The predictive or monitoring marker for Alzheimer's disease

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Anti-apoptotic Therapy (Intrathecal Injection of Anti-apoptotic PTD-FNK Protein) in a Mouse Model of Amyotrophic Lateral Sclerosis

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Development of therapy for deposits of AB and tau in Alzheimer disease.

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[Book] 神経内科外来シリーズ／もの忘れ外来2016

Author(s)

Kawarabayashi Takeshi 瓦林毅

Takeshi Kawarabayashi 瓦林毅

KAWARABAYASHI Takeshi 瓦林毅

[Book] よくわかって役に立つ認知症のすべて改訂第3版2011