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Suzuki Takeshi  鈴木 岳之

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… Alternative Names

SUZUKI Takeshi  鈴木 岳之

鈴木 岳之  スズキ タケシ

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Researcher Number 90187740
Other IDs
Affiliation (based on the past Project Information) *help 2020 – 2022: 慶應義塾大学, 薬学部(芝共立), 教授
2011 – 2013: 慶應義塾大学, 薬学部, 准教授
2008: Keio University, 薬学部, 准教授
2007: Kyoritsu University of Pharmacy, 薬学部, 准教授
2006: 共立薬科大学, 薬学部, 助教授 … More
1994 – 1996: 共立薬科大学, 薬学部, 助教授
1992: 共立薬科大学, 薬学部・薬理学, 講師
1992: 共立薬科大学, 薬学部薬理学, 講師
1991: 共立薬科大学, 薬理学教室, 講師
1987 – 1990: 共立薬科大学, 薬学部, 講師 Less
Review Section/Research Field
Principal Investigator
Basic Section 58010:Medical management and medical sociology-related / Biological pharmacy / General pharmacology / Biological pharmacy
Except Principal Investigator
Biological pharmacy
Keywords
Principal Investigator
グルタミン酸 / 神経変性疾患 / 承認申請 / 医薬品売上 / アンメットメディカルニーズ / ライフサイクルマネジメント / 産業経済分析 / 医薬品開発 / 希少疾患 / 適応 … More / 医薬品市場 / 薬価 / 製薬企業 / 新薬 / 医薬品産業 / 脊髄 / パロキセチン / ミクログリア / ATP / 神経炎症 / 興奮毒性 / 情報伝達 / 薬理学 / 神経毒性 / ALS(筋萎縮性側索硬化症) / タモキシフェン / ノックアウトマウス / RNA編集 / ADAR2 / カルシウム / 筋萎縮性側索硬化症 / AMPA受容体 / グルタミン酸受容体 / 中枢・末梢神経 / 神経細胞死 / non-NMDA受容体 / 運動神経 / 中隔野神経 / レチノイン酸 / コリンアセチル転移酵素(ChAT) / アセチルコリン(ACh) / Septal cell / Nerve growth factor / Cyclic AMP / ChAT / Calcium / Acetylcholine … More
Except Principal Investigator
アセチルコリン / radioimmunoassay / acetylcholine / ラジオイムノアッセイ / microdialysis / hippocampus / serotonin(5-HT) / 海馬 / アセチルコリン遊離 / brain slices / AF-DX 116 / pirenzepine / M_1 receptor / ileal longitudinal muscle / 誘導体 / TRH / ラット前脳基底核 / モルモット回腸縦走筋 / シナプス前M, 受容体 / Nーメチルスコポラミン / AFーDX116 / ラジオイム@アッセイ / アトロピン / テレンゼピン / ピレンゼピン / M_1受容体 / 脳スライス / 回腸縦走筋標本 / atropine / isoproterenol / desipramine(DMI) / 5-HT_<1A> receptor / 血液 / 多形核白血球 / 単核白血球 / ニトロプルシド / ニトログリセリン / 細胞障害 / サイクリックGMP / 一酸化窒素 / バッフィ-コ-ト / Fonnum法 / 抗アセチルコリン抗体 / コリンアセチルトランスフェラ-ゼ / 神経細胞死 / NMDA / グルタミン酸 / アセチルコリン産生 / 血球アセチルコリン含量 / バッフィ-・コ-ト / リンパ球アセチルコリン含量 / 血球アセルチルコリン含量 / 血漿アセチルコリン含量 Less
  • Research Projects

    (13 results)
  • Research Products

    (35 results)
  • Co-Researchers

    (11 People)
  •  The pharmaceutical market and drug development prognosis in Japan.Principal Investigator

    • Principal Investigator
      Suzuki Takeshi
    • Project Period (FY)
      2020 – 2022
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 58010:Medical management and medical sociology-related
    • Research Institution
      Keio University
  •  Study on the glutamate-induced spinal neurodysfunction.Principal Investigator

    • Principal Investigator
      SUZUKI Takeshi
    • Project Period (FY)
      2011 – 2013
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Biological pharmacy
    • Research Institution
      Keio University
  •  Study of AMPA receptor dysfunctions in CNS diseasesPrincipal Investigator

    • Principal Investigator
      SUZUKI Takeshi
    • Project Period (FY)
      2006 – 2008
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      General pharmacology
    • Research Institution
      Keio University
      Kyoritsu University of Pharmacy
  •  中枢コリン作動性神経由来細胞株を用いた神経死モデルの確立Principal Investigator

    • Principal Investigator
      鈴木 岳之
    • Project Period (FY)
      1997
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      Kyoritsu University of Pharmacy
  •  抗うつ薬の海馬コリン作動性神経活性に及ぼす作用の検討

    • Principal Investigator
      川島 紘一郎
    • Project Period (FY)
      1995
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      Biological pharmacy
    • Research Institution
      Kyoritsu University of Pharmacy
  •  海馬でのアセチルコリン遊離調節におけるセロトニンの役割

    • Principal Investigator
      川島 紘一郎
    • Project Period (FY)
      1994
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      Biological pharmacy
    • Research Institution
      Kyoritsu University of Pharmacy
  •  神経成長因子によるカルシウムチャンネル発現調節の解析Principal Investigator

    • Principal Investigator
      鈴木 岳之
    • Project Period (FY)
      1994
    • Research Category
      Grant-in-Aid for Encouragement of Young Scientists (A)
    • Research Field
      Biological pharmacy
    • Research Institution
      Kyoritsu University of Pharmacy
  •  細胞機能障害時における中枢コリン作動性神経変性過程の解析

    • Principal Investigator
      川島 紘一郎
    • Project Period (FY)
      1992
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      Kyoritsu University of Pharmacy
  •  ヒト血球細胞中におけるアセチルコリンの局在と生合成能の検討

    • Principal Investigator
      川島 絋一郎
    • Project Period (FY)
      1992
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      Biological pharmacy
    • Research Institution
      Kyoritsu University of Pharmacy
  •  細胞機能障害時における中枢コリン作動性神経変性過程の解析

    • Principal Investigator
      川島 紘一郎
    • Project Period (FY)
      1991
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      Kyoritsu University of Pharmacy
  •  新しい特異的なコリンアセチルトランスフェラ-ゼ活性測定法の開発とその応用

    • Principal Investigator
      川島 紘一郎
    • Project Period (FY)
      1991
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      Biological pharmacy
    • Research Institution
      Kyoritsu University of Pharmacy
  •  血中アセチルコリン(ACh)の測定とその生理的意義の解明

    • Principal Investigator
      KAWASHIMA Koichiro
    • Project Period (FY)
      1989 – 1990
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      Biological pharmacy
    • Research Institution
      Kyoritsu University of Pharmacy
  •  Investigation on regulatory mechanism of acetylcholine release at cholinergic nerve endings.

    • Principal Investigator
      KAWASHIMA Koichiro
    • Project Period (FY)
      1987 – 1988
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      Biological pharmacy
    • Research Institution
      Kyoritsu College of Pharmacy

All 2023 2022 2020 2014 2013 2012 2009 2008 2007 2006 Other

All Journal Article Presentation

  • [Journal Article] An Empirical Analysis of Japan's Drug Development Lag Behind the United States2022

    • Author(s)
      Nakamura Hiroshi、Wakutsu Naohiko、Murayama Satoshi、Suzuki Takeshi
    • Journal Title

      The Journal of Clinical Pharmacology

      Volume: - Issue: 7 Pages: 847-854

    • DOI

      10.1002/jcph.2023

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-16K03700, KAKENHI-PROJECT-20K10328, KAKENHI-PROJECT-21K01526
  • [Journal Article] A study on the description of anticancer drug combination therapy in the package insert in Japan.2020

    • Author(s)
      Shibata S, Matsushita M, Tsukamoto K, Chiba K, Ozaki K, Suzuki T.
    • Journal Title

      BPB Reports

      Volume: 3 Pages: 157-165

    • NAID

      130007944904

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20K10328
  • [Journal Article] Japanese Pharmaceutical Industry: Recent Perspectives and Areas for Further Research2020

    • Author(s)
      Shibata S, Ozaki K, Suzuki T.
    • Journal Title

      J Regulatory Sci

      Volume: 8 Pages: 1-13

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20K10328
  • [Journal Article] L-glutamate released from activated microglia downregulates astrocytic L-glutamate transporter expression in neuroinflammation : the 'collusion' hypothesis for increased extracellular L-glutamate concentration in neuroinflammation2013

    • Author(s)
      Takaki J, Fujimori K, Miura M, Suzuki T, Sekino Y, Sato K
    • Journal Title

      Journal of Neuroinflammation

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23590113
  • [Journal Article] L-glutamate released from activated microglia downregulates astrocytic L-glutamate transporter expression in neuroinflammation: the 'collusion' hypothesis for increased extracellular L-glutamate concentration in neuroinflammation.2012

    • Author(s)
      Takaki J
    • Journal Title

      J Neuroinflammation

      Volume: 9 Issue: 1 Pages: 275-275

    • DOI

      10.1186/1742-2094-9-275

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21700422, KAKENHI-PROJECT-23590113
  • [Journal Article] Cell-autonomous enhancement of glutamate-uptake by female astrocytes.2012

    • Author(s)
      Morizawa Y, Sato K, Takaki J, Kawasaki A, Shibata K. Suzuki T, Ohta S, Koizumi S.
    • Journal Title

      Cellular and Molecular Neurobiology

      Volume: 32 Pages: 953-956

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23590113
  • [Journal Article] Cell-autonomous enhancement of glutamate-uptake by female astrocytes.2012

    • Author(s)
      Morizawa, Y
    • Journal Title

      Molecular and Cellular Neurobiology

      Volume: 32 Issue: 6 Pages: 953-956

    • DOI

      10.1007/s10571-012-9829-z

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21240034, KAKENHI-PROJECT-21700422, KAKENHI-PROJECT-23590113, KAKENHI-PROJECT-23790287
  • [Journal Article] RNA editing of the Q/R site of GluA2 in different cultured cell lines that constitutively express different levels of RNA editing enzyme ADAR2.2012

    • Author(s)
      Yamashita T, Tadami C, Nishimoto Y, Hideyama T, Kimura D, Suzuki T, Kwak S.
    • Journal Title

      Neuroscience Research

      Volume: 73 Pages: 42-48

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23590113
  • [Journal Article] Quantitative expression of AMPA receptor subunits in HEK293 cells2007

    • Author(s)
      Suzuki T et al.
    • Journal Title

      The Journal of Kyoritsu University of Pharmacy 2

      Pages: 1-8

    • NAID

      120000801774

    • Data Source
      KAKENHI-PROJECT-18590239
  • [Journal Article] Quantitative expression of AMPA receptor subunits in HEK293 cells2007

    • Author(s)
      Suzuki T, Shimotohno K, Nakamura T, Brorson JR
    • Journal Title

      JKyoritsu Univ Pharm 2

      Pages: 1-8

    • NAID

      120000801774

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18590239
  • [Presentation] 日本における医薬品産業の市場特性分析と、継続的に新薬創出を行うためのプラットフォーム策定に関する検討2023

    • Author(s)
      鈴木岳之
    • Organizer
      日本薬学会第143年会
    • Data Source
      KAKENHI-PROJECT-20K10328
  • [Presentation] 日本における抗programmed cell death protein 1 (ligand 1) 抗体薬の ライフサイクルマネジメントの検討2022

    • Author(s)
      松本大夢、柴田翔洋、河添 仁、鈴木岳之
    • Organizer
      日本薬学会第142 年
    • Data Source
      KAKENHI-PROJECT-20K10328
  • [Presentation] 抗うつ薬とP2X4受容体の相互作用の比較検討2014

    • Author(s)
      笠原由佳, 三浦麻利衣, 最上由香里, 関野祐子, 佐藤薫, 鈴木岳之
    • Organizer
      日本薬学会第134回年会
    • Place of Presentation
      熊本
    • Data Source
      KAKENHI-PROJECT-23590113
  • [Presentation] P2X4 receptor -mediated acceleration of microglial activation is important for the L-glutamate release from activated microglia in the early stage of inflammation2013

    • Author(s)
      Sato K, Fujimori K, Takaki J, Suzuki T, Sekino Y
    • Organizer
      Neuro2013
    • Place of Presentation
      京都
    • Data Source
      KAKENHI-PROJECT-23590113
  • [Presentation] Paroxetine prevented the activation of microglia by suppressing P2X4 receptor activation.2013

    • Author(s)
      Fujimori K, Takaki J, Sato K, Suzuki T.
    • Organizer
      第86回日本薬理学会年会
    • Place of Presentation
      福岡
    • Data Source
      KAKENHI-PROJECT-23590113
  • [Presentation] Paroxetine prevented the activation of microglia by suppressing P2X4 receptor activation2013

    • Author(s)
      Fujimori K, Takaki J, Sato K, Suzuki T
    • Organizer
      第86回日本薬理学会年会
    • Place of Presentation
      福岡
    • Data Source
      KAKENHI-PROJECT-23590113
  • [Presentation] Effect of antidepressants on the functional impairment of L-glu transporters under the inflammatory condition2012

    • Author(s)
      Fujimori K, Takaki J, Sato K, Suzuki T
    • Organizer
      第85回日本薬理学会年会
    • Place of Presentation
      京都
    • Data Source
      KAKENHI-PROJECT-23590113
  • [Presentation] Paroxetine prevents the functional impairment of L-glutamate transporters in inflammation by modulating microglial glutamate release2012

    • Author(s)
      Fujimori K, Takaki J, Sato K, Suzuki T
    • Organizer
      第35回日本神経科学大会
    • Place of Presentation
      名古屋
    • Data Source
      KAKENHI-PROJECT-23590113
  • [Presentation] Paroxetine prevents the functional impairment of L-glutamate transporters in inflammation by modulating microglial glutamate release.2012

    • Author(s)
      Fujimori K, Takaki J, Sato K, Suzuki T.
    • Organizer
      第35回日本神経科学大会
    • Place of Presentation
      名古屋
    • Data Source
      KAKENHI-PROJECT-23590113
  • [Presentation] Effect of antidepressants on the functional impairment of L-glu transporters under the inflammatory condition.2012

    • Author(s)
      藤森康希, 高木淳平, 佐藤薫, 鈴木岳之
    • Organizer
      第85回日本薬理学会年会
    • Place of Presentation
      京都
    • Data Source
      KAKENHI-PROJECT-23590113
  • [Presentation] タモキシフェン誘導性ADAR2ノックアウトマウスを用いた孤発性ALS神経細胞死の検討2009

    • Author(s)
      木村大輔、日出山拓人、鈴木岳之、郭伸
    • Organizer
      第82回日本薬理学会年会
    • Place of Presentation
      横浜
    • Data Source
      KAKENHI-PROJECT-18590239
  • [Presentation] 孤発性筋萎縮性側索硬化症におけるRNA編集酵素異常2009

    • Author(s)
      日出山拓人、山下雄也、鈴木岳之、木村大輔、辻省次、樋口美代子、シーバーグ・ペーター、高橋良輔、三澤日出巳、郭伸
    • Organizer
      第82回日本薬理学会年会
    • Place of Presentation
      横浜
    • Data Source
      KAKENHI-PROJECT-18590239
  • [Presentation] タモキシフェン誘導性ノックアウトマウスを用いた孤発性ALSの神経細胞死の検討2008

    • Author(s)
      木村大輔、日出山拓人、鈴木岳之、郭伸
    • Organizer
      第81回日本薬理学会年会
    • Place of Presentation
      横浜
    • Data Source
      KAKENHI-PROJECT-18590239
  • [Presentation] Slow neuronal death of motor neurons in sporadic ALS mouse model by RNA editing enzyme ADAR2 knockout2008

    • Author(s)
      Hideyama T, Yamashita T, Tsuji S, Misawa H, Takahashi R, Suzuki T, KwakS
    • Organizer
      The 38th annual meetng of the society for neuroscience
    • Place of Presentation
      Washington D.C., USA
    • Data Source
      KAKENHI-PROJECT-18590239
  • [Presentation] Spontaneous synaptic activities observed in co-cultured conditions of rat sptal and hippocampal neurons2007

    • Author(s)
      Suzuki T, Iijima S, Nakamura T
    • Organizer
      Neuroscience 2007
    • Place of Presentation
      San Diego, USA
    • Data Source
      KAKENHI-PROJECT-18590239
  • [Presentation] Establishment of a novel Hela cell line atably expressing the half-edited GluR2 transcript2007

    • Author(s)
      Yamashita T, Tadami C, Nishimoto Y, Kimura D, Suzuki T, Kwak S
    • Organizer
      Neuroscience 2007
    • Place of Presentation
      San Diego, USA
    • Data Source
      KAKENHI-PROJECT-18590239
  • [Presentation] RNA編集異常による孤発性ALSモデルマウスの開発2007

    • Author(s)
      郭 伸、日出山 拓人、西本 祥仁、山下 雄也、辻 省次、高橋 良輔、三澤 日出巳、鈴木 岳之
    • Organizer
      第30回日本神経科学学会
    • Place of Presentation
      横浜
    • Year and Date
      2007-09-10
    • Data Source
      KAKENHI-PROJECT-18590239
  • [Presentation] Spontaneous synaptic activities observed in co-culturedconditions of rat sptal and hippocampal neurons.2007

    • Author(s)
      T Suzuki, S Iijima, T Nakamura
    • Organizer
      Neuroscience 2007
    • Place of Presentation
      San Diego, USA
    • Year and Date
      2007-11-04
    • Data Source
      KAKENHI-PROJECT-18590239
  • [Presentation] Establishment of a novel Hela cell line atably expressing the half-edited GluR2 transcript.2007

    • Author(s)
      T Yamashita, C Tadami, Y Nishimoto, D Kimura, T Suzuki, S Kwak
    • Organizer
      Neuroscience 2007
    • Place of Presentation
      San Diego, USA
    • Year and Date
      2007-11-06
    • Data Source
      KAKENHI-PROJECT-18590239
  • [Presentation] Tet-Onシステムを利用したRNA編集活性測定株の確立2007

    • Author(s)
      山下雄也、只見智恵子、西本祥仁、木村大輔、鈴木岳之、郭伸
    • Organizer
      第30回日本神経科学学会
    • Place of Presentation
      横浜
    • Data Source
      KAKENHI-PROJECT-18590239
  • [Presentation] RNA 編集異常による孤発性ALSモデルマウスの開発2007

    • Author(s)
      郭伸、日出山拓人、西本祥仁、山下雄也、辻省次、高橋良輔、三澤日出巳、鈴木岳之
    • Organizer
      第30 回日本神経科学学会
    • Place of Presentation
      横浜
    • Data Source
      KAKENHI-PROJECT-18590239
  • [Presentation] Type 2 (Ca^<2+> permeable) AMPA receptor : Its phenotype expression roles in neuronal vulnerability in neurodegeneration diseases2006

    • Author(s)
      Suzuki T, Brorson JR, Kwak S
    • Organizer
      10th International Conference on Alzheimer's Disease and Related Disorders
    • Place of Presentation
      Madrid, Spain
    • Data Source
      KAKENHI-PROJECT-18590239
  • [Presentation] 抗うつ薬とP2X4受容体の相互作用の比較検討.

    • Author(s)
      笠原由佳, 三浦麻利衣, 最上由香里, 関野祐子, 佐藤薫, 鈴木岳之.
    • Organizer
      日本薬学会第134回年会
    • Place of Presentation
      熊本
    • Data Source
      KAKENHI-PROJECT-23590113
  • [Presentation] Neural differentiation potentials in human embryonic stem cell lines.

    • Author(s)
      福本大悟, 松本拓也, 岡田洋平, 末盛博文, 中辻憲夫, 鈴木岳之, 赤松和土, 岡野栄之.
    • Organizer
      第87回日本薬理学会年会
    • Place of Presentation
      仙台
    • Data Source
      KAKENHI-PROJECT-23590113
  • [Presentation] P2X4 receptor-mediated acceleration of microglial activation is important for the L-glutamate release from activated microglia in the early stage of inflammation.

    • Author(s)
      Sato K, Fujimori K, Takaki J, Suzuki T, Sekino Y.
    • Organizer
      Neuro2013
    • Place of Presentation
      京都
    • Data Source
      KAKENHI-PROJECT-23590113
  • 1.  KAWASHIMA Koichiro (70095008)
    # of Collaborated Projects: 8 results
    # of Collaborated Products: 0 results
  • 2.  FUJIMOTO Kazuko (50229043)
    # of Collaborated Projects: 8 results
    # of Collaborated Products: 0 results
  • 3.  KWAK Shin (40160981)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 11 results
  • 4.  藤井 健志 (80255380)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 5.  OOHATA Hisayo
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 6.  MASHINO Tadahiko (90165697)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 7.  IIJIMA Shiro (30222798)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 2 results
  • 8.  SATO Kaoru (10311391)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 12 results
  • 9.  中村 洋 (60286656)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 10.  山田 直司
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 11.  和久津 尚彦
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results

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