Nata Koji 那谷耕司

… Alternative Names

那谷耕司ナタコウジ

NATA Koji 那谷耕司

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Researcher Number	90202233
Other IDs
External Links
Affiliation (Current)	2025: 岩手医科大学, 薬学部, 非常勤講師
Affiliation (based on the past Project Information) *help	2022 – 2023: 岩手医科大学, 薬学部, 教授 2007 – 2010: Iwate Medical University, School of pharmacy, Professor 2006: Tohoku University, Graduate School of Medicine, Research Associate, 大学院医学系研究科, 助手 2005: 東北大学, 大学院・医学系研究科, 助手 1999 – 2002: Graduate School of Medicine, Tohoku University, Research Associate, 大学院・医学系研究科, 助手 1991 – 1998: 東北大学, 医学部, 助手
Review Section/Research Field	Principal Investigator Structural biochemistry / Pathological medical chemistry / General medical chemistry / General medical chemistry / Functional biochemistry / Pathological medical chemistry Except Principal Investigator General medical chemistry / Gastroenterology / Pathological medical chemistry / Basic Section 54040:Metabolism and endocrinology-related / General medical chemistry / Functional biochemistry / Structural biochemistry
Keywords	Principal Investigator Regeneration / Reg / 糖尿病 / cyclic ADP-ribose / Pancreatic islet β-cells / Diabetes mellitus / カルシウムイオン / 細胞内情報伝達物質 / cyclic ADP-ribose hydrolase / CD38 … More / luciferase assay / calcium channel / ryanodine receptor / FK506 binding protein / FK506 / gene family / 遺伝子ファミリー / Regenerating gene / Pancreatic isletβ-cells / 再生遺伝子 / Gene Targeting / 膵β細胞 / クローニング / 染色体座位 / ADP-ribosyl cyclase / genomicクローニング / Reg receptor / the Reg gene family / pancreatic β-cell / knockout mouse / diabetes mellitus / reeenerative medicine / Reg受容体 / Regファミリー / 遺伝子改変マウス / 移植・再生医療 / 再生医学 / chromosomal localization / FISH法 / BAC clone / Cre-lox P system / Cre-lox P システム / Cre-lox Pシステム / BACクローン / Cer-lox Pシステム / South-western blot analysis / gel shift assay / Transcriptional activation / ルシフェラーゼアッセイ / 炎症 / サイトカイン / サウス・ウェスタン法 / ゲルシフトアッセイ / 遺伝子発現誘導 / Reg gene family / Pancreatic islet beta-cells / Regneration / Reg遺伝子ファミリー / Pancreatic oslet β-cells / 遺伝性多発性外骨腫 / 遺伝性多発外骨腫 / EXTファミリー / 膵ランゲルハンス島 / ノックアウトマウス / EXTL3 / 糖転移酵素 / ヘパラン硫酸 / 糖鎖 / ATP / ADP-ribose cyclase / site-directed mutagenesis / cDNAクローニング / 分子進化 / ペプチドホルモン / Pancreatic Polypeptide / Neuropeptidey / Peptide YY … More Except Principal Investigator CD38 / cyclic ADP-ribose / second messenger / トランスジェニックマウス / cyclic ADP-ribose hydrolase / ADP-ribosyl cyclase / insulin secretion / Cyclic ADP-ribose / サイクリックADPリボース / 糖尿病 / Pancreatic islet β-cells / pancreatic islet β-cells / Ca^<2+> mobilization / CICR / FKBP12.6 / knockout mouse / カルシウムイオン / ノックアウトマウス / familial pancreatitis / 遺伝子異常 / 慢性膵炎 / transgenic mouse / Insulin secretion / Second messenger / Vasoactive Intestinal Peptide / セカンドメッセンジャー / 糖負荷試験 / グルコース / インスリン / 膵β細胞 / 遺伝子クローニング / インスリン分泌 / 部位特異的変異法 / 細胞内情報伝達物質 / 創薬 / 2型糖尿病 / Ucp1 / 熱産生 / 褐色脂肪細胞 / 肥満 / Autism / Social recognition / Splicing / Ryanodine receptor / FKBP / 発現制御 / 循環器・高血圧 / シグナル伝達 / 遺伝子 / 自閉症 / 社会認識異常 / スプライシング / リアノジン受容体 / cardiac hypertrophy / cardiomyocytes / intracellular Ca^<2+> / muscle force / 心臓肥大 / 細胞内Ca^<2+>ブール / 心肥大 / 心筋 / 細胞内Ca^<2+> / 筋張力 / Trypsinogen gene mutation / Hereditary pancreatitis / Chronic pancreatitis / 遺伝性膵炎 / トリプシノーゲン遺伝子 / diabetes mellitus / pancreatic beta cell / calcium ion / insulin / 環状ADPリボース / hereditary disease / molecular biology / chronic pancreatitis / 遺伝性慢性膵炎 / 家族性膵炎 / 遺伝性疾患 / 分子生物学 / molecular cloning / 部位特異的点突然変異導入法 / microsome / Quantitative method / Pancreatic islet beta-cells / 抗cyclic ADP-ribose抗体 / サクシニルcyclic ADP-ribose / 測定法 / Ca2+ mobilization / 抗cyclicADP-ribose抗体 / Cs^<2+>mobilization / cyclicADP-ribose / 定量法 / Genetic engineering / Peptidyamidoglycolate lyase / Monooxygenase / Peptidylglycine hydroxylase / Reconstitution / Two-step mechanism / C-terminal alpha-amidation / 分泌 / トランスフェクション / cDNA / 発現ベクタ- / 発現ベクター / ヒスチジン / ペプチドC末端アミド化酵素 / PHM-27 / 水酸化グリシン脱アルキルアミド化酵素 / 再構成系 / 遺伝子組換え法 / ペプチジルアミドグリコレートリアーゼ / モノオキシゲナーゼ / ペプチジルグリシン水酸化酵素 / 2段階反応 / ペプチドC末端アミド化 / Amino acid sequence / Purification / DNA synthesis / 遺伝子組換え / 再生増殖 / インスリン産生細胞 / 染色体座位 / 遺伝子ファミリー / Gene targeting / Transgenic mouse / Regeneration / Reg / Ca2+mobilization / Ca^<2+>mobilization Less

肥満症の治療と健康寿命の延伸を目指した褐色脂肪細胞機能活性化の試み
- Principal Investigator
  
  石垣泰
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 54040:Metabolism and endocrinology-related
- Research Institution
  Iwate Medical University
Reduceds β-cell proliferation and impaired glucose tolerance in pancreatics β-cell specific Extl3 knockout mice.Principal Investigator
- Principal Investigator
  
  NATA Koji
- Project Period (FY)
  2008 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Pathological medical chemistry
- Research Institution
  Iwate Medical University
Targeted disruption of the Reg protein receptor gene : The relationship of the Reg-Reg receptor system with pancreatic 13-cell replication.Principal Investigator
- Principal Investigator
  
  NATA Koji
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General medical chemistry
- Research Institution
  Iwate Medical University
  Tohoku University
Regulation of the CD38-cyclic ADP-ribose signal system by tissue-specific slicing of ryanodine receptor
- Principal Investigator
  
  TAKASAWA Shin
- Project Period (FY)
  2005 – 2006
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  General medical chemistry
- Research Institution
  Tohoku University
Physiological and pathological Roles of the CD38/cyclic ADP-ribose signal system in cardiac myocytes
- Principal Investigator
  
  TAKASAWA Shin, 加藤一郎
- Project Period (FY)
  2000 – 2002
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Pathological medical chemistry
- Research Institution
  Tohoku University
Structure and transcriptional regulation of gene encoding human FK506 binding protein 12 and 12.6Principal Investigator
- Principal Investigator
  
  NATA Koji
- Project Period (FY)
  2000 – 2001
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Pathological medical chemistry
- Research Institution
  TOHOKU University
Targeted disruption of all the Reg family genes: A new animal model for regeneration deficient disordersPrincipal Investigator
- Principal Investigator
  
  NATA Koji
- Project Period (FY)
  1999 – 2001
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Pathological medical chemistry
- Research Institution
  Tohoku University
Mechanisms for transcriptional activation of Reg (Regenerating gene)Principal Investigator
- Principal Investigator
  
  NATA Koji
- Project Period (FY)
  1998 – 1999
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General medical chemistry
- Research Institution
  TOHOKU UNIVERSITY
cyclic ADP-ribose合成・分解酵素(CD38)の活性調節機構の解明Principal Investigator
- Principal Investigator
  
  那谷耕司
- Project Period (FY)
  1996
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General medical chemistry
- Research Institution
  Tohoku University
インスリン産生細胞活性化因子の精製とその性質
- Principal Investigator
  
  米倉秀人
- Project Period (FY)
  1996
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Structural biochemistry
- Research Institution
  Kanazawa University
Generation of animal model of diabetes by disrupting the ADP-ribosyl cyclase (CD38) gene
- Principal Investigator
  
  KATO Ichiro
- Project Period (FY)
  1996 – 1998
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  General medical chemistry
- Research Institution
  Tohoku University
Targeted disruption of Reg gene : A new animal model of diabetes and pancreatitis.Principal Investigator
- Principal Investigator
  
  NATA Koji
- Project Period (FY)
  1996 – 1997
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Functional biochemistry
- Research Institution
  TOHOKU University
Study for the molecular pathogenesis of the idiopathic chronic pancreatitis, especially familial pancreatitis
- Principal Investigator
  
  KOIZUMI Masaru
- Project Period (FY)
  1996 – 1997
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Gastroenterology
- Research Institution
  Tohoku University
インスリン産生細胞増殖因子Reg蛋白質を用いた糖尿病治療法の開発
- Principal Investigator
  
  米村豊, 岡本宏
- Project Period (FY)
  1995 – 1997
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  General medical chemistry
- Research Institution
  Kanazawa University
  Tohoku University
トランスジェニックマウスを用いたサイクリックADPリボースの膵β細胞内機能の解明
- Principal Investigator
  
  KATO Ichiro
- Project Period (FY)
  1995
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  General medical chemistry
- Research Institution
  Tohoku University
cyclic ADP-ribose合成・分解酵素の活性発現に必須な一次構造の解明Principal Investigator
- Principal Investigator
  
  那谷耕司
- Project Period (FY)
  1995
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Structural biochemistry
- Research Institution
  Tohoku University
ヒトcyclic ADP-ribose合成酵素(CD38)の遺伝子構造と発現Principal Investigator
- Principal Investigator
  
  那谷耕司
- Project Period (FY)
  1994
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Structural biochemistry
- Research Institution
  Tohoku University
Mechanism of cyclic ADP-ribose hydrolysis in mammalian cells.
- Principal Investigator
  
  TAKASAWA Shin
- Project Period (FY)
  1994 – 1995
- Research Category
  
  Grant-in-Aid for General Scientific Research (B)
- Research Field
  
  General medical chemistry
- Research Institution
  Tohoku University
Clinical study for the pathogenesis of idiopathic chronic pancreatitis.
- Principal Investigator
  
  KOIZUMI Masaru
- Project Period (FY)
  1994 – 1995
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Gastroenterology
- Research Institution
  Tohoku University
ATP依存性に蓄積された膵β細胞小胞体CaのサイクリックADPリボースによる放出
- Principal Investigator
  
  OKAMOTO Hiroshi
- Project Period (FY)
  1993 – 1994
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Tohoku University
新しい細胞内情報伝達物質サイクリックADPリボースの合成酵素と受容体の解明
- Principal Investigator
  
  岡本宏
- Project Period (FY)
  1993 – 1996
- Research Category
  
  Grant-in-Aid for General Scientific Research (A)
- Research Field
  
  General medical chemistry
- Research Institution
  Tohoku University
ヒトPeptide YY遺伝子の構造と染色体座位の決定Principal Investigator
- Principal Investigator
  
  那谷耕司
- Project Period (FY)
  1993
- Research Category
  
  Grant-in-Aid for Encouragement of Young Scientists (A)
- Research Field
  
  Structural biochemistry
- Research Institution
  Tohoku University
Establishment of a quantitative method for determining cyclic ADP-ribose concentration
- Principal Investigator
  
  YONEKURA Hideto
- Project Period (FY)
  1993 – 1995
- Research Category
  
  Grant-in-Aid for Developmental Scientific Research (B)
- Research Field
  
  Functional biochemistry
- Research Institution
  Tohoku University
Production of the two enzymes concerned in peptide C-terminal alpha-amidation by genetic engineering and in vitro reconstitution of peptide C-terminal alpha-amidation reaction
- Principal Investigator
  
  OKAMOTO Hiroshi
- Project Period (FY)
  1991 – 1993
- Research Category
  
  Grant-in-Aid for Developmental Scientific Research (B)
- Research Field
  
  Pathological medical chemistry
- Research Institution
  TOHOKU UNIVERSITY

All 2024 2011 2010 2009 2008 2007 2006 2005

All Journal Article Presentation

[Journal Article] A newly identified compound activating UCP1 inhibits obesity and its related metabolic disorders.2024
- Author(s)
  Onodera K, Hasegawa Y, Yokota N, Tamura S, Kinno H, Takahashi I, Chiba H, Kojima H, Katagiri H, Nata K, Ishigaki Y.
- Journal Title
  
  Obesity
  
  Volume: 32 Issue: 2 Pages: 324-338
- DOI
  10.1002/oby.23948
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22K08676, KAKENHI-PROJECT-21K08582
[Journal Article] All-trans retinoic acid and a novel synthetic retinoid tamibarotene (Am80) differentially regulate CD38 expression in human leukemia HL-60 cells : possible involvement of protein kinase C-δ.2011
- Author(s)
  Uruno A, Noguchi N, Matsuda K, Nata K, Yoshikawa T, Chikamatsu Y, Kagechika H, Harigae H, Ito S, Okamoto H, Sugawara A.
- Journal Title
  
  J Leukoc Biol. in press
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590312
[Journal Article] A novel ryanodine receptor expressed in pancreatic islets by alternative splicing from type 2 ryanodine receptor gene.2010
- Author(s)
  Takasawa S, Kuroki M, Nata K, Noguchi N, Ikeda T, Yamauchi A, Ota H, Itaya-Hironaka A, Sakuramoto-Tsuchida S, Takahashi I, Yoshikawa T, Shimosegawa T, Okamoto H.
- Journal Title
  
  Biochem Biophys Res Commun. Vol.397
  
  Pages: 140-145
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590312
[Journal Article] Thiazolidinediones inhibit REG Iα gene transcription in gastrointestinal cancer cells.2009
- Author(s)
  Yamauchi A, Takahashi I, Takasawa S, Nata K, Noguchi N, Ikeda T, Yoshikawa T, Shervani NJ, Suzuki I, Uruno A, Unno M, Okamoto H, Sugawara A.
- Journal Title
  
  Biochem Biophys Res Commun. vol.379
  
  Pages: 743-748
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590312
[Journal Article] Important role of heparan sulfate in the morphogenesis, s-cell proliferation, and insulin secretion of mouse pancreatic islets.2009
- Author(s)
  Takahashi I, Noguchi N, Nata K, Yamada S, Kaneiwa T, Mizumoto S, Ikeda T, Sugihara K, Asano M, Yoshikawa T, Yamauchi A, Shervani NJ, Uruno A, Kato I, Unno M, Sugahara K, Takasawa S, Okamoto H, Sugawara A.
- Journal Title
  
  Biochem Biophys Res Commun. vol.383
  
  Pages: 113-118
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590312
[Journal Article] FKBP12.6 disruption impairs glucose-induced insulin secretion.2008
- Author(s)
  Noguchi N, Yoshikawa T, Ikeda T, Takahashi I, Shervani NJ, Uruno A, Yamauchi A, Nata K, Takasawa S, Okamoto H, Sugawara A.
- Journal Title
  
  Biochem Biophys Res Commun. vol.371
  
  Pages: 735-740
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590312
[Journal Article] Reg蛋白質受容体欠損マウスの作製とそのβ細胞複製能の低下2007
- Author(s)
  那谷耕司
- Journal Title
  
  糖尿病 50
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18590255
[Journal Article] Reg蛋白質受容体欠損マウスの作製とそのβ細胞複製能の低下2007
- Author(s)
  那谷耕司
- Journal Title
  
  糖尿病 50(In press)
- Data Source
  KAKENHI-PROJECT-17390072
[Journal Article] Reg蛋白質受容体欠損マウスの作製とそのβ細胞複製能の低下2007
- Author(s)
  那谷耕司
- Journal Title
  
  糖尿病 50 Supplement 1 (in press)
- Data Source
  KAKENHI-PROJECT-18590255
[Journal Article] Targeted disruption of mouse Reg protein receptor gene causes impaired pancreatic islet cell replication and embryonic lethality.2006
- Author(s)
  Nata, K.
- Journal Title
  
  20^<th> IUBMB Congress Abstract
  
  Pages: 565-565
- Data Source
  KAKENHI-PROJECT-17390072
[Journal Article] Targeted disruption of mouse Reg protein receptor gene causes impaired pancreatic islet cell replication and embryonic lethality.2006
- Author(s)
  Nata K.
- Journal Title
  
  20^<th> IUBMB International Congress of Biochemistry and Molecular Biology and 11^<th> FAOBMB Congress
  
  Pages: 565-565
- Data Source
  KAKENHI-PROJECT-18590255
[Journal Article] Embryonic lethality caused by targeted disruption of the mouse Reg protein receptor gene.2005
- Author(s)
  Nata, K.
- Journal Title
  
  生化学 77
  
  Pages: 1031-1031
- Data Source
  KAKENHI-PROJECT-17390072
[Journal Article] Molecular cloning, expression and chromosomal localization of a novel human REG family gene, REG III.2005
- Author(s)
  Nata, K.
- Journal Title
  
  Diabetes 54
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17390072
[Journal Article] 新規ヒトREGファミリー遺伝子(REGIII)の単離:ヒトREGファミリーは5つの遺伝子によって構成されている2005
- Author(s)
  那谷耕司
- Journal Title
  
  糖尿病 48
- Data Source
  KAKENHI-PROJECT-17390072
[Presentation] Structural characterization of heparan sulfate in the Extl3 knockout mice and the pancreatic β-cell specific Extl3 knockout mice.2010
- Author(s)
  Kaneiwa T, Yamada S, Sugahara K, Takahashi I, Noguchi N, Nata K, Okamoto H, Sugawara A
- Organizer
  25th International Carbohydrate Symposium.
- Place of Presentation
  Tokyo
- Year and Date
  2010-08-02
- Data Source
  KAKENHI-PROJECT-20590312
[Presentation] Contribution of heparan sulfate fine structure to Insulin secretion.2010
- Author(s)
  Takahashi I, Ohashi K, Shervani NJ, Nata K.
- Organizer
  第33回日本分子生物学会年会・第83回日本生化学会大会合同大会
- Place of Presentation
  神戸
- Year and Date
  2010-12-09
- Data Source
  KAKENHI-PROJECT-20590312
[Presentation]2010
- Author(s)
  Shervani NJ, Takahashi I, Ohashi K, Noguchi N, Okamoto H, Takasawa S, Sugawara A, Nata K.
- Organizer
  第53回日本糖尿病学会年次学術集会
- Place of Presentation
  岡山
- Year and Date
  2010-05-29
- Data Source
  KAKENHI-PROJECT-20590312
[Presentation] Autoantibodies to REG family proteins in Japanese diabetes patients.2009
- Author(s)
  Shervani NJ, Noguchi N, Ikeda T, Takahashi I, Yoshikawa T, Uruno A, Nata K, Takasawa S, Okamoto H, Sugawara A
- Organizer
  45th Annual Meeting of the European Association for the Study of Diabetes.
- Place of Presentation
  Vienna
- Data Source
  KAKENHI-PROJECT-20590312
[Presentation] Structural characterization of heparan sulfate in conventional and conditional Extl3-deficient mice.2009
- Author(s)
  Kaneiwa T, Yamada S, Sugahara K, Takahashi I, Noguchi N, Nata K, Okamoto H, Sugawara A
- Organizer
  Hokkaido University-Mahidol University Joint Symposium.
- Place of Presentation
  Sapporo
- Year and Date
  2009-05-12
- Data Source
  KAKENHI-PROJECT-20590312
[Presentation] Autoimmunity against REG family antigens in Japanese diabetes patients.2009
- Author(s)
  Shervani NJ, Nata K, Noguchi N, Takahashi I, Ikeda T, Yamauchi A, Yoshikawa T, Uruno A, Takasawa S, Okamoto H, Sugawara A
- Organizer
  The 20th World Diabetes Congress.
- Place of Presentation
  Montreal
- Data Source
  KAKENHI-PROJECT-20590312
[Presentation] 2型リアノジン受容体遺伝子にはGG-AG配列で切断されるイントロンが存在する2009
- Author(s)
  池田崇之, 野口直哉, 吉川雄朗, 宇留野晃, 那谷耕司, 高澤伸, 岡本宏, 米倉秀人, 菅原明
- Organizer
  第82回日本生化学会大会
- Place of Presentation
  神戸
- Year and Date
  2009-10-23
- Data Source
  KAKENHI-PROJECT-20590312
[Presentation] Extl3ノックアウトマウスにおけるヘパラン硫酸の分析2009
- Author(s)
  金岩知之, 山田修平, 菅原一幸, 高橋巌, 野口直哉, 那谷耕司, 岡本宏, 菅原明
- Organizer
  日本薬学会第129年会
- Place of Presentation
  京都
- Year and Date
  2009-03-26
- Data Source
  KAKENHI-PROJECT-20590312
[Presentation] All-trans retinoic acid and a novel synthetic retinoid tamibarotene (Am80) differentially regulate CD38 expression in human leukemia HL-60 cells : possible involvement of protein kinase C-δ.2009
- Author(s)
  Uruno A, Noguchi N, Nata K, Yoshikawa T, Takahashi I, Shervani NJ, Chikamatsu Y, Kagechika H, Harigae H, Ito S, Okamoto H, Sugawara A
- Organizer
  The Endocrine Society 91st Annual Meeting.
- Place of Presentation
  Washington, DC
- Data Source
  KAKENHI-PROJECT-20590312
[Presentation] Sera from Japanese diabetes patients show autoimmunity to REG family antigens.2009
- Author(s)
  Shervani NJ, Nata K, Noguchi N, Takahashi I, Ikeda T, Ohashi K, Yoshikawa T, Uruno A, Takasawa S, Okamoto H, Sugawara A
- Organizer
  第82回日本生化学会大会
- Place of Presentation
  神戸
- Year and Date
  2009-10-23
- Data Source
  KAKENHI-PROJECT-20590312
[Presentation] ヘパラン硫酸はマウス膵ランゲルハンス島の形態形成やβ細胞増殖,インスリン分泌機能に重要な役割を果たしている2008
- Author(s)
  高橋巌, 野口直哉, 那谷耕司, 山田修平, 金岩知之, 水本秀二, 池田崇之, 杉原一司, 浅野雅秀, 吉川雄朗, Nausheen J. Shervani, 宇留野晃, 海野倫明, 菅原一幸, 高澤伸, 岡本宏, 菅原明
- Organizer
  第31回日本分子生物学会年会・第81回日本生化学会大会
- Place of Presentation
  神戸
- Year and Date
  2008-12-09
- Data Source
  KAKENHI-PROJECT-20590312
[Presentation] Impaired glucose-induced insulin secretion in FK506-binding protein 12.6-deficient mice.2008
- Author(s)
  Yoshikawa T, Noguchi N, Ikeda T, Takahashi I, Shervani NJ, Uruno A, Yamauchi A, Nata K, Takasawa S, Okamoto H, Sugawara A
- Organizer
  The American Diabetes Association 68th Scientific Sessions.
- Place of Presentation
  San Francisco
- Year and Date
  2008-06-08
- Data Source
  KAKENHI-PROJECT-20590312
[Presentation] マウス膵ランゲルハンス島の形態形成やβ細胞増殖,インスリン分泌機能におけるヘパラン硫酸の重要性2008
- Author(s)
  高橋巌, 野口直哉, 那谷耕司, 山田修平, 金岩知之, 水本秀二, 池田崇之, 杉原一司, 浅野雅秀, 吉川雄朗, Nausheen J. Shervani, 宇留野晃, 海野倫明, 菅原一幸, 高澤伸, 岡本宏, 菅原明
- Organizer
  第20回分子糖尿病学シンポジウム
- Place of Presentation
  東京
- Year and Date
  2008-12-13
- Data Source
  KAKENHI-PROJECT-20590312
[Presentation] FK506結合蛋白質12.6ノックアウトマウスにおけるグルコース刺激インスリン分泌の低下2008
- Author(s)
  吉川雄朗, 野口直哉, 池田崇之, 高橋巌, Nausheen J. Shervani, 宇留野晃, 山内晶世, 那谷耕司, 高澤伸, 岡本宏, 菅原明
- Organizer
  第51回日本糖尿病学会年次学術集会
- Place of Presentation
  東京
- Year and Date
  2008-05-23
- Data Source
  KAKENHI-PROJECT-20590312
[Presentation] Reduced β-cell proliferation and impaired glucose tolerance in β-cell specific Extl3 knockout mice.2008
- Author(s)
  Takahashi I, Nata K, Noguchi N, Ikeda T, Sugihara K, Asano M, Yoshikawa T, Yamauchi A, Shervani NJ, Uruno A, Unno M, Takasawa S, Okamoto H, Sugawara A
- Organizer
  44th Annual Meeting of the European Association for the Study of Diabetes.
- Place of Presentation
  Rome
- Data Source
  KAKENHI-PROJECT-20590312
[Presentation] 膵β細胞特異的糖転移酵素Extl3欠損マウスはβ細胞増殖能低下と耐糖能異常を生じる2008
- Author(s)
  高橋巌, 那谷耕司, 野口直哉, 池田崇之, 吉川雄朗, 山内晶世, Nausheen J. Shervani, 宇留野晃, 杉原一司, 浅野雅秀, 海野倫明, 高澤伸, 岡本宏, 菅原明
- Organizer
  第51回日本糖尿病学会年次学術集会
- Place of Presentation
  東京
- Year and Date
  2008-05-24
- Data Source
  KAKENHI-PROJECT-20590312
[Presentation] Reg蛋白質受容体欠損マウスの作製とそのβ細胞複製能の低下2007
- Author(s)
  那谷耕司
- Organizer
  第50回日本糖尿病学会
- Place of Presentation
  仙台
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18590255
[Presentation] Targeted disruption of mouse Reg protein receptor gene causes impaired pancreatic islet cell replication and embryonic lethality2006
- Author(s)
  Nata K.
- Organizer
  20th IUBMB International Congress of Biochemistry and Molecular Biology and 11th FAOBMB Congress
- Place of Presentation
  Kyoto,Japan
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18590255
[Presentation] Targeted disruption of mouse Reg protein receptor gene causes impaired pancreatic islet cell replication and embryonic lethality2006
- Author(s)
  Nata, K
- Organizer
  20th IUBMB International Congress of Biochemistry and Molecular Biology and ll`h FAOBMB Congress
- Place of Presentation
  Kyoto, Japan
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590255

1. TAKASAWA Shin (50187944)

# of Collaborated Projects: 13 results

# of Collaborated Products: 0 results
2. YONEKURA Hideto (80240373)

# of Collaborated Projects: 7 results

# of Collaborated Products: 0 results
3. KATO Ichiro (50250741)

# of Collaborated Projects: 7 results

# of Collaborated Products: 0 results
4. OKAMOTO Hiroshi (60025632)

# of Collaborated Projects: 6 results

# of Collaborated Products: 0 results
5. KOIZUMI Masaru (40111281)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
6. SHIMOSEGAWA Tooru (90226275)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
7. NOGUCHI Naoya (20333792)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
8. 米村豊 (20167042)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
9. SUGAWARA Akira (90270834)

# of Collaborated Projects: 1 results

# of Collaborated Products: 19 results
10. SATO Kenichi (10282055)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. TOHGO Akira (40282123)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. KAGAYA Yutaka (90250779)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
13. 山岸昌一 (40281026)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
14. 石垣泰 (50375002)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
15. 長谷川豊 (90451559)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
16. MORIIZUMI S

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
17. 納谷耕司

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
18. NAYA K

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results

Nata Koji 那谷 耕司

那谷 耕司 ナタ コウジ

NATA Koji 那谷 耕司

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Reduceds β-cell proliferation and impaired glucose tolerance in pancreatics β-cell specific Extl3 knockout mice.Principal Investigator

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Targeted disruption of the Reg protein receptor gene : The relationship of the Reg-Reg receptor system with pancreatic 13-cell replication.Principal Investigator

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Structure and transcriptional regulation of gene encoding human FK506 binding protein 12 and 12.6Principal Investigator

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Targeted disruption of all the Reg family genes: A new animal model for regeneration deficient disordersPrincipal Investigator

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Mechanisms for transcriptional activation of Reg (Regenerating gene)Principal Investigator

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cyclic ADP-ribose合成・分解酵素(CD38)の活性調節機構の解明Principal Investigator

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Targeted disruption of Reg gene : A new animal model of diabetes and pancreatitis.Principal Investigator

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Nata Koji 那谷耕司

那谷耕司ナタコウジ

NATA Koji 那谷耕司